ID RL24_DICDI Reviewed; 127 AA.
AC Q54VN6;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 10-JUN-2026, entry version 107.
DE RecName: Full=Large ribosomal subunit protein eL24 {ECO:0000305};
DE AltName: Full=60S ribosomal protein L24;
GN Name=rpl24; ORFNames=DDB_G0280229;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL24 family.
CC {ECO:0000305}.
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DR EMBL; AAFI02000035; EAL67341.1; -; Genomic_DNA.
DR RefSeq; XP_641319.1; XM_636227.1.
DR PDB; 5AN9; EM; 3.30 A; G=1-69.
DR PDB; 5ANB; EM; 4.10 A; G=1-69.
DR PDB; 5ANC; EM; 4.20 A; G=1-69.
DR PDB; 6QKL; EM; 3.30 A; G=1-69.
DR PDBsum; 5AN9; -.
DR PDBsum; 5ANB; -.
DR PDBsum; 5ANC; -.
DR PDBsum; 6QKL; -.
DR AlphaFoldDB; Q54VN6; -.
DR SMR; Q54VN6; -.
DR FunCoup; Q54VN6; 593.
DR STRING; 44689.Q54VN6; -.
DR PaxDb; 44689-Q54VN6; -.
DR GeneID; 8622451; -.
DR KEGG; ddi:DDB_G0280229; -.
DR dictyBase; DDB_G0280229; rpl24.
DR VEuPathDB; AmoebaDB:DDB_G0280229; -.
DR eggNOG; KOG1722; Eukaryota.
DR HOGENOM; CLU_106411_2_0_1; -.
DR InParanoid; Q54VN6; -.
DR OMA; PGHGKKM; -.
DR PhylomeDB; Q54VN6; -.
DR Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR Reactome; R-DDI-9954709; Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide.
DR Reactome; R-DDI-9954714; PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA.
DR Reactome; R-DDI-9954716; ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA.
DR EvolutionaryTrace; Q54VN6; -.
DR PRO; PR:Q54VN6; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR CDD; cd00472; Ribosomal_L24e_L24; 1.
DR Gene3D; 6.10.250.1270; -; 1.
DR Gene3D; 2.30.170.20; Ribosomal protein L24e; 1.
DR InterPro; IPR038630; L24e/L24_sf.
DR InterPro; IPR056366; Ribosomal_eL24.
DR InterPro; IPR000988; Ribosomal_eL24-rel_N.
DR InterPro; IPR023442; Ribosomal_eL24_CS.
DR PANTHER; PTHR10792; 60S RIBOSOMAL PROTEIN L24; 1.
DR PANTHER; PTHR10792:SF1; RIBOSOMAL PROTEIN L24; 1.
DR Pfam; PF01246; Ribosomal_L24e; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS01073; RIBOSOMAL_L24E; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..127
FT /note="Large ribosomal subunit protein eL24"
FT /id="PRO_0000323428"
FT REGION 93..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..127
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 7..9
FT /evidence="ECO:0007829|PDB:5AN9"
FT STRAND 20..22
FT /evidence="ECO:0007829|PDB:5AN9"
FT STRAND 28..33
FT /evidence="ECO:0007829|PDB:6QKL"
FT HELIX 34..42
FT /evidence="ECO:0007829|PDB:5AN9"
FT TURN 46..48
FT /evidence="ECO:0007829|PDB:5AN9"
FT HELIX 53..58
FT /evidence="ECO:0007829|PDB:5AN9"
FT TURN 64..67
FT /evidence="ECO:0007829|PDB:5AN9"
SQ SEQUENCE 127 AA; 14793 MW; A8284E2A21908F69 CRC64;
MKTSLCNYSE FKIYPARGMK FVRGDSKVFH FINTKVESLF FRKINPRDIR WSMVYRRIYK
NTTTDVSAKK KARKTKKVER NIVGASLEVI QQKRAQKPEV KQAAAEQAKR EIKEKKKAAA
KKAAPKK
//
