ID S6BP36_METRE Unreviewed; 637 AA.
AC S6BP36;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 28-JAN-2026, entry version 61.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:BAN50799.1};
GN ORFNames=PCA10_50670 {ECO:0000313|EMBL:BAN50799.1};
OS Metapseudomonas resinovorans NBRC 106553.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Pseudomonadales; Pseudomonadaceae; Metapseudomonas.
OX NCBI_TaxID=1245471 {ECO:0000313|EMBL:BAN50799.1, ECO:0000313|Proteomes:UP000015503};
RN [1] {ECO:0000313|EMBL:BAN50799.1, ECO:0000313|Proteomes:UP000015503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 106553 {ECO:0000313|EMBL:BAN50799.1,
RC ECO:0000313|Proteomes:UP000015503};
RX PubMed=23887915; DOI=10.1128/genomeA.00488-13;
RA Shintani M., Hosoyama A., Ohji S., Tsuchikane K., Takarada H., Yamazoe A.,
RA Fujita N., Nojiri H.;
RT "Complete Genome Sequence of the Carbazole Degrader Pseudomonas
RT resinovorans Strain CA10 (NBRC 106553).";
RL Genome Announc. 1:e00488-13(2013).
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AP013068; BAN50799.1; -; Genomic_DNA.
DR RefSeq; WP_016494926.1; NC_021499.1.
DR AlphaFoldDB; S6BP36; -.
DR STRING; 1245471.PCA10_50670; -.
DR KEGG; pre:PCA10_50670; -.
DR PATRIC; fig|1245471.3.peg.5138; -.
DR eggNOG; COG3276; Bacteria.
DR HOGENOM; CLU_023030_2_0_6; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000015503; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:BAN50799.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000015503}.
FT DOMAIN 1..169
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 637 AA; 69751 MW; 08B5B995155429E9 CRC64;
MIVGTAGHID HGKTALLKAL TGQEGDRRPA ERERGITIDL GYLHADLGDG QPTAFIDVPG
HERFVHNMLA GACGIDLLLL VVAADDGVMP QTREHLAIAE LLGIRRALVA LTKIGRVEAR
RVERARSEVQ ALLAPGPLAG AEFFPVDSLS GTGIDALRQA LLAEAALVKG RGSDGHFRLP
IDRAFSVSGA GLVVTGTAFA GRVRVGDELV LAPSGRVVRV RGLHARNQQV ADAEAGQRVA
LNISGERLAL EQIHRGDWLL APALLAPTTR LDIDLHLLPG ERHDLAHWTS VHVHLGAQDV
TGRVALLEAG SLAPGHHAVA QLLLNAPVHA VHGDRLVLRD QSAQRTLGGG RVLDPFAPAR
NRRTPARLAQ LEALRGDGLE TALPTLLGAA HNGLDPQRLE RQFNRPRDGW ALPAGVVEVS
TRLGPRLFAE DRWHALEQQL LDGLARFHGE LPDELGPDRD RLRRYALPEL ERSVFIAQLE
RQLASGAVQA SGPWLHLPDH RVQLNEAEEA LRQRIWPLLD AGQFDPPWVR DLSKELNVEE
SAMRLLQRKL ARLGLLHQVV KDLFYPDATI RQLATLARQL QDEHGSIKAA HWRDRLAIGR
KRSIQLLEYL DRIGFTRRIG DLRKIREDSA LAQAPTP
//
