ID T1G3J0_HELRO Unreviewed; 208 AA.
AC T1G3J0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 08-OCT-2025, entry version 51.
DE RecName: Full=CYTH domain-containing protein {ECO:0000259|PROSITE:PS51707};
GN Name=20215638 {ECO:0000313|EnsemblMetazoa:HelroP79038};
GN ORFNames=HELRODRAFT_79038 {ECO:0000313|EMBL:ESO04805.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP79038, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO04805.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP79038}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMQM01004234; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096457; ESO04805.1; -; Genomic_DNA.
DR RefSeq; XP_009017384.1; XM_009019136.1.
DR AlphaFoldDB; T1G3J0; -.
DR STRING; 6412.T1G3J0; -.
DR EnsemblMetazoa; HelroT79038; HelroP79038; HelroG79038.
DR GeneID; 20215638; -.
DR KEGG; hro:HELRODRAFT_79038; -.
DR CTD; 20215638; -.
DR eggNOG; ENOG502S5G9; Eukaryota.
DR HOGENOM; CLU_105907_0_0_1; -.
DR InParanoid; T1G3J0; -.
DR OMA; HWLRHRE; -.
DR OrthoDB; 442176at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IBA:GO_Central.
DR GO; GO:0050333; F:thiamine triphosphate phosphatase activity; IEA:InterPro.
DR GO; GO:0042357; P:thiamine diphosphate metabolic process; IBA:GO_Central.
DR FunFam; 2.40.320.10:FF:000015; Predicted protein; 1.
DR Gene3D; 2.40.320.10; Hypothetical Protein Pfu-838710-001; 1.
DR InterPro; IPR033469; CYTH-like_dom_sf.
DR InterPro; IPR023577; CYTH_domain.
DR InterPro; IPR039582; THTPA.
DR PANTHER; PTHR14586; THIAMINE-TRIPHOSPHATASE; 1.
DR PANTHER; PTHR14586:SF1; THIAMINE-TRIPHOSPHATASE; 1.
DR Pfam; PF01928; CYTH; 1.
DR SMART; SM01118; CYTH; 1.
DR SUPFAM; SSF55154; CYTH-like phosphatases; 1.
DR PROSITE; PS51707; CYTH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 1..192
FT /note="CYTH"
FT /evidence="ECO:0000259|PROSITE:PS51707"
SQ SEQUENCE 208 AA; 24168 MW; DD36766B892051CB CRC64;
MIEIEKKFVV NDEILNKMLS LGAKLIKRES FTDVYYDTEC HCLTTKNFWL RQRDEVWQLK
SPTGHRTFEE GLFNSSYKET EKEDEIVNLI EPVLNQKYSQ NQKCGLAEFL KLCNCQPFCK
MTTHRQSYKL QDKFKIDLDV TDSGYAVGEI EMMINSETDI AEATNKIEDL SKKLELPITQ
AVSGKVSSFL KSNDPEHYKK LFNLKIIA
//
