ID U1NQP0_9EURY Unreviewed; 628 AA.
AC U1NQP0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 05-FEB-2025, entry version 38.
DE SubName: Full=Deoxycytidine triphosphate deaminase {ECO:0000313|EMBL:ERG99498.1};
GN ORFNames=J07HQX50_00645 {ECO:0000313|EMBL:ERG99498.1};
OS Haloquadratum sp. J07HQX50.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Halobacteria; Halobacteriales; Haloferacaceae; Haloquadratum.
OX NCBI_TaxID=1238426 {ECO:0000313|EMBL:ERG99498.1, ECO:0000313|Proteomes:UP000030642};
RN [1] {ECO:0000313|EMBL:ERG99498.1, ECO:0000313|Proteomes:UP000030642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J07HQX50 {ECO:0000313|Proteomes:UP000030642};
RX PubMed=23637883;
RA Podell S., Ugalde J.A., Narasingarao P., Banfield J.F., Heidelberg K.B.,
RA Allen E.E.;
RT "Assembly-driven community genomics of a hypersaline microbial ecosystem.";
RL PLoS ONE 8:E61692-E61692(2013).
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DR EMBL; KE356562; ERG99498.1; -; Genomic_DNA.
DR AlphaFoldDB; U1NQP0; -.
DR STRING; 1238426.J07HQX50_00645; -.
DR HOGENOM; CLU_423691_0_0_2; -.
DR Proteomes; UP000030642; Unassembled WGS sequence.
DR GO; GO:0008829; F:dCTP deaminase activity; IEA:InterPro.
DR GO; GO:0006229; P:dUTP biosynthetic process; IEA:InterPro.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR GO; GO:0015949; P:nucleobase-containing small molecule interconversion; IEA:TreeGrafter.
DR CDD; cd00081; Hint; 1.
DR CDD; cd07557; trimeric_dUTPase; 2.
DR Gene3D; 2.70.40.10; -; 2.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 2.
DR InterPro; IPR011962; dCTP_deaminase.
DR InterPro; IPR036157; dUTPase-like_sf.
DR InterPro; IPR033704; dUTPase_trimeric.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR006141; Intein_N.
DR NCBIfam; TIGR02274; dCTP_deam; 1.
DR NCBIfam; TIGR01445; intein_Nterm; 1.
DR PANTHER; PTHR42680; DCTP DEAMINASE; 1.
DR PANTHER; PTHR42680:SF3; DCTP DEAMINASE; 1.
DR Pfam; PF22769; DCD; 2.
DR Pfam; PF14890; Intein_splicing; 1.
DR SMART; SM00305; HintC; 1.
DR SUPFAM; SSF51283; dUTPase-like; 2.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide metabolism {ECO:0000256|ARBA:ARBA00023080}.
FT DOMAIN 498..550
FT /note="Hint"
FT /evidence="ECO:0000259|SMART:SM00305"
FT REGION 588..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..628
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 68813 MW; 5CD5CE3390BD73F5 CRC64;
MILSDEDILA RLESGELVVT PIDDIDMQVQ PASIDLRLGE EFLEFQRTNI SCIHPNRESE
VSEYVTERHV PEGEEFILHP SDFVLGTTKE RVEIPADLLA TVEGRSSLGR LAVVIHASLP
ADEEVFVWTP QSGFGFHPIG DIVDNEDPAH AVSFHPQTLT VRTHRISNYI KNPTRRIFKI
TLASGRSVHV TRDHNLFSLD ASGKIDRVRS ENTQNRLVAV PGSMPAPHNA ESSLDLRSVF
AGSTRTAPVA TDGAASESES KSTAAVLLNR GDEWLPSQLT LTPAFGRLVG VWIRNQIADQ
HTIPQVGTPL EHVGHGCERP VIAETVTGID IRSPLVDELL QQLCRGETGP QMPSCVWNWD
DAVIQGVLQG LLASRSLTGT VMTKTKQLAS KICYLATRLG RYGSIDDSET VSRGYCVRVH
PAPPEKRIPT PGHLLAEYRH QAGLDRHSIT ERADLPESSL KAIETMKRPE ITQSTLKTLQ
EVYQDAGIDT DRLDRIVSSD IQFDRVVSVR DTERIEPTYD LEVQPNGRVI ENFLGGTGGV
FLSNTAGIVD PGYEGQITLE LSNLGTAPVA LTPGMRVSQL VFTELKSESN RPYGAARGSK
YQGQRGPQAS RIGSDPEFDN NGDNGDGE
//
