ID V4CQH9_LOTGI Unreviewed; 1561 AA.
AC V4CQH9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 02-APR-2025, entry version 52.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=LOTGIDRAFT_170557 {ECO:0000313|EMBL:ESP04720.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP04720.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP04720.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB199652; ESP04720.1; -; Genomic_DNA.
DR RefSeq; XP_009044619.1; XM_009046371.1.
DR STRING; 225164.V4CQH9; -.
DR EnsemblMetazoa; LotgiT170557; LotgiP170557; LotgiG170557.
DR GeneID; 20241453; -.
DR KEGG; lgi:LOTGIDRAFT_170557; -.
DR CTD; 20241453; -.
DR HOGENOM; CLU_001832_9_1_1; -.
DR OMA; ESWITEC; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:TreeGrafter.
DR GO; GO:0003723; F:RNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR056245; KH_DEAH11/12.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF81; ATP-DEPENDENT RNA HELICASE DEAH11, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF24471; KH_DEAH11; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00847; HA2; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 1540..1560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1253..1302
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..10
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1561 AA; 179355 MW; 8A9EB7CBE1EE07A2 CRC64;
MYSYHQSESA TELKVKRKHH SFKDPYENRQ YEGPDIPPYG GTDAESSTNE VTSHMLTYSG
PLSSRPVNCE RKPSALAFNG NDCLRQPGES GDTKNVEENH LSNSNRGKLA QHTKFFTRQE
ENDDSKQSKK NETPNLDQSN DSSANVDLIE TNRLKSYVHL KSETNQKVSH HSIPSLQPED
NDSFYQVQSK GNSQRNRSRR RKSNNHEATK NNQKAFHHVI SKTSSHQQAI CHSKTERNES
SCQDQSKSNS LNPDRNLTYP KGTKINPPII QDKSIPSKVH LPNHFQKIVT CPKSKPSRNF
YVLLLRGELS ISFVALLDII LGPDSKHNLL SIDVEPILDL ESTTINFSDV QKAEQALKQL
REFNCQNLLC TWTPVDKRIE ILKTYFNDFE LHSSDILKTH DEKIQAIRKQ LESCAFDEKE
ALKMRKEELI LQLRELTSFS ETVRESLRRS ILLEDEQSPP DAAIQTAIET LEELGSIKDD
RITDIGKWLV KIPLEPRFGC MIKKGFEMGF AYETIVFTAL CSSSGSIFYR GGNDQQKKRS
DLKKLTFCDT KGDAFTYLKI YKEWEQVTEK RKNKWCFDNA LNSKTLRGAR ELVNEICSIF
KHNWSILVKK TFSTKVELEE ALQNIILFAF YENIAHSLGH NRMGYYIPNL RQRVFVHPSS
ALNSLNDSSQ WLVFINILKT SRDYITVVTP VEESWIRKIT SLKTKQFDID EAKKKSVCSV
RNQFFGSTTY SFFVGPAYTK LKAYGDLLYE SVQVPVVLEA DRKTGEVKFI CAFNATIPDD
LIDDWVTEAK SHVIQRTAEY KVGPNNQAGG VRIVLGLGGE GQLILMPDEY RNIHIKSSGK
ETSKETVVDK FKRFGQIVDC WEDKRSYYRW GRVTFSTPEA AAEAAMSVKS LREVRILGKS
CSISLGKKQH RPVLFHKVPK TVTEQDIRNC LPNDSQRRAI TKISIIREKT FTNPNEIPYF
QQQIHDQFQE FDHDMKFVVD VMKPYDSNNN FRAFIKFNDA SQGTMACDAL RGRLIINGQK
ANLTPKLSSS LSVPEQVYQL LEDEIEDFTA ELRENGTEFK LDSKKLNNER RVFNISASNS
HDLVQIRYGL AAIVQGEVME YWSNENNRYL FLKSGREFLR SLEKRTITIL QVDNTLLSLR
VFGLEDNILM AQNAIDQYLG NMVEGDGRRE IKLDGESQPK GLMKTLVIRY DLELEGFVQA
SGLQSALLNH HNQTLKISGD SASIEKATGL IESLATELRN KITKTKSVEL PDCCSCLCPV
QSMDYIYRLE ACGHAYCLDC IKRQITVAVQ SKELPVLCVN CQDPLVWSDF EFCFKRLQIN
PLDLVRTAVS VYMIRNKDGY RHCLTPDCAM VYRITKKSDV FNCNECGLRI CTSCHVEYHD
GLTCAMLKSS SDVDSDMEKY LRENATRFEL TILNMFELTI LKMFELTILD MFELTILNMF
ELTILDLFEL TILNMFELTI LKMFELTILN MFELTILDMF ELTILNMFEL TILDLFELTI
LNMFELTILN MFELTILNMF ELTILNMFKL TILNMFELTI LNMFELTIMN MFELTILNMF
K
//
