ID V5FYS0_PAEV5 Unreviewed; 378 AA.
AC V5FYS0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 10-JUN-2026, entry version 30.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:GAD93772.1};
GN ORFNames=PVAR5_2387 {ECO:0000313|EMBL:GAD93772.1};
OS Paecilomyces variotii (strain NBRC 109023 / No. 5) (Byssochlamys
OS spectabilis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=1356009 {ECO:0000313|EMBL:GAD93772.1, ECO:0000313|Proteomes:UP000018001};
RN [1] {ECO:0000313|Proteomes:UP000018001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 5 / NBRC 109023 {ECO:0000313|Proteomes:UP000018001};
RX PubMed=24407650; DOI=10.1128/genomea.01162-13;
RA Oka T., Ekino K., Fukuda K., Nomura Y.;
RT "Draft genome sequence of the formaldehyde-resistant fungus Byssochlamys
RT spectabilis No. 5 (anamorph Paecilomyces variotii No. 5) (NBRC109023).";
RL Genome Announc. 2:E0116213-E0116213(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD93772.1}.
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DR EMBL; BAUL01000066; GAD93772.1; -; Genomic_DNA.
DR AlphaFoldDB; V5FYS0; -.
DR FunCoup; V5FYS0; 230.
DR eggNOG; KOG2380; Eukaryota.
DR HOGENOM; CLU_031403_0_0_1; -.
DR InParanoid; V5FYS0; -.
DR OrthoDB; 5399569at2759; -.
DR Proteomes; UP000018001; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:TreeGrafter.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:EnsemblFungi.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:L-tyrosine biosynthetic process; IEA:EnsemblFungi.
DR FunFam; 1.10.3660.10:FF:000002; Prephenate dehydrogenase [NADP(+)]; 1.
DR FunFam; 1.10.3660.10:FF:000004; Prephenate dehydrogenase [NADP(+)]; 1.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR050812; Preph/Arog_dehydrog.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF27505; 6PGD_Tyr1_C; 1.
DR Pfam; PF20463; PDH_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018001}.
FT DOMAIN 1..235
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 378 AA; 42641 MW; F04573B4A0C959AA CRC64;
MNSLDPKYVD RHCFSVGNSF VEAGAIDKIV AEYGPSTKVG AIVGGQTSCK APELAAFDKH
LPPDVEILSC HSLHGPNVNP KGQPLVLIQH RATDKSLRFV EQVFESFESK YVYLTGEMHD
RITADTQAVT HAAFLSMGTA WAANNQFPWE INRWVGGIEN VKINITLRIY ANKWHVYAGL
AILNPSAKKQ IRQYAESVTD LYKLMIGGHR EELKRRVKAA GAAVFRVGTE GQDLLLRDEV
LDRFSLSKVS REKAPPNNHL SLLAIVDCWS KLGIVPYDHM ICSTPLFRLW LGVTEYLFRN
PDLLDEVLDI AIDDNTFRSD DLEFTFAARA WSDCVSFGDF ESYRDRFERI QGYFAPRFPE
AVRVGNEMLK TILEKTAH
//
