ID V6JI85_STRRC Unreviewed; 621 AA.
AC V6JI85;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 28-JAN-2026, entry version 46.
DE SubName: Full=Translation elongation factor {ECO:0000313|EMBL:EST19607.1};
GN ORFNames=M878_41800 {ECO:0000313|EMBL:EST19607.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST19607.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST19607.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST19607.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST19607.1}.
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DR EMBL; AWQX01000375; EST19607.1; -; Genomic_DNA.
DR AlphaFoldDB; V6JI85; -.
DR STRING; 1352936.M878_41800; -.
DR PATRIC; fig|1352936.5.peg.8656; -.
DR HOGENOM; CLU_023030_1_1_11; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EST19607.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000313|EMBL:EST19607.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984}.
FT DOMAIN 1..171
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 584..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..621
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 621 AA; 66359 MW; 69D70ED47ED594B1 CRC64;
MRVLATAGHV DHGKSALVRA LTGMEPDRHL EERRRGLTLD LGFVWTRLGP DGDHLAFVDV
PGHERFVPTM LAGVGPVPAV LFVVAADQGW QPQSEEHLAV LDALGVRHAV LAVTRSDLAD
PEPVRADAVE RLARTSLGKV PAVAVSALTG AGLDALRREL ELLAGELADP DPDADVRLWL
DRAFTVRGHG TVVTGTLGAG TLRAGDRLVT GDGPRVLRVR GLQTLHEERT AVGGVARVAV
NLHGQGADDL RRGQVLLTPD CWSRSDVLDV RVTGEPVARL PRSVTLHIGT AAVPVTVRPL
GDDTARLTLA RGLPLRVGDR AVLREPGGGR TPCGATVLDV RPPRLTRRGA GRARAAELAA
LTGRPDGAGE LRRRRLIRRA DLLAMGVLAP AEPVAGDWLV DDAHWIALRD RLAAEVQRHA
KEDPLEPGLP TEAARRLLGL PDRALVDALA GTMPRLRTRQ GRLYTADSIG PDLPRPVRAA
VDAVRQDLAR APFRAPEAGR LVQLGLNRRA LAAAVTAGAL LRIADGIVLL PGADAEAAAE
LRALPQPFTL SAARRALDTT RRVAVPLLEF LDARGYTERV DDQRRRCRTG EGSPCTDAVN
GVDGDGRESN PPARDPRTPR F
//
