ID V8C9B4_9HELI Unreviewed; 534 AA.
AC V8C9B4;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 28-JAN-2026, entry version 38.
DE SubName: Full=Apolipoprotein N-acyltransferase {ECO:0000313|EMBL:ETD23346.1};
GN ORFNames=HMPREF2086_01148 {ECO:0000313|EMBL:ETD23346.1};
OS Helicobacter macacae MIT 99-5501.
OC Bacteria; Pseudomonadati; Campylobacterota; Epsilonproteobacteria;
OC Campylobacterales; Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1357400 {ECO:0000313|EMBL:ETD23346.1, ECO:0000313|Proteomes:UP000018731};
RN [1] {ECO:0000313|EMBL:ETD23346.1, ECO:0000313|Proteomes:UP000018731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 99-5501 {ECO:0000313|EMBL:ETD23346.1,
RC ECO:0000313|Proteomes:UP000018731};
RX PubMed=25212613;
RA Shen Z., Sheh A., Young S.K., Abouelliel A., Ward D.V., Earl A.M.,
RA Fox J.G.;
RT "Draft genome sequences of six enterohepatic helicobacter species isolated
RT from humans and one from rhesus macaques.";
RL Genome Announc. 2:e00857-e00814(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the CN hydrolase family. Apolipoprotein N-
CC acyltransferase subfamily. {ECO:0000256|ARBA:ARBA00010065}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETD23346.1}.
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DR EMBL; AZJI01000005; ETD23346.1; -; Genomic_DNA.
DR RefSeq; WP_023927871.1; NZ_KI669454.1.
DR AlphaFoldDB; V8C9B4; -.
DR STRING; 1357400.HMPREF2086_01148; -.
DR PATRIC; fig|1357400.3.peg.1559; -.
DR eggNOG; COG0815; Bacteria.
DR HOGENOM; CLU_050649_0_0_7; -.
DR OrthoDB; 9804277at2; -.
DR Proteomes; UP000018731; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016410; F:N-acyltransferase activity; IEA:InterPro.
DR GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR004563; Apolipo_AcylTrfase.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR059109; Lnt_membrane_dom.
DR PANTHER; PTHR38686; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR38686:SF1; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR Pfam; PF26365; ApoNAT_membrane; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:ETD23346.1};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipoprotein {ECO:0000313|EMBL:ETD23346.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018731};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ETD23346.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 311..534
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
SQ SEQUENCE 534 AA; 60254 MW; B06B284D05D8D3F4 CRC64;
MKKNPQKNNS SKKSPTSYLH FYKILKNMID FFRAKLDFIA NIPKLSLPSL VRFDKSQWQN
FALLNYYGLI FGILFSAWLY AFVGIVEVCG GFSDNVSMWL NMFGVIALSA LGIVSIACYL
LAPVRIRFYF GFFAGILLLY WIALSFRYTP FPFLIPLVWL GIGLIIGAIF WVLLFFKHII
FRIFTLMILG SIHPFGFDWL VPQSFFAYSA FGVSEWDFFF VVVGVALLVV ALLRSDINFP
KKSKKSHSSS LRPSVRIYIG FFGVISLALA LDIDGLGGKH TQTSTDSSTQ LIAKSSTDSS
DLFLRGNFAL AQTYFKQDFK WSKSALDEIK ETTFSTIEQA KINGKKAIIL PETILPIVLD
SQIATLEELQ SISDDIAIIL GAFSKPNFNS TYIIHKGEVQ ILNKVILAPF GEKMPLPDFL
AKPLLKLFFG IDEGLDSASA PQDFVLFERV FRNAICYEGT SKELYADSPN LVVMISNNGW
FYPSIEPYLQ RTLMKYYARK AKSTILHSAN LSPSFILSSK VLDDNFDTVI HIKD
//
