ID V8NQ86_OPHHA Unreviewed; 453 AA.
AC V8NQ86;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 18-JUN-2025, entry version 32.
DE RecName: Full=Platelet-derived growth factor receptor-like protein {ECO:0000256|ARBA:ARBA00019671};
DE Flags: Fragment;
GN Name=KIT {ECO:0000313|EMBL:ETE64111.1};
GN ORFNames=L345_10121 {ECO:0000313|EMBL:ETE64111.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE64111.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE64111.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE64111.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBUNIT: Forms a complex composed of PDGFRL, TNK2 and GRB2.
CC {ECO:0000256|ARBA:ARBA00011360}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE64111.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZIM01002391; ETE64111.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NQ86; -.
DR SMR; V8NQ86; -.
DR OrthoDB; 6077854at2759; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR FunFam; 2.60.40.10:FF:000422; Mast/stem cell growth factor receptor; 1.
DR FunFam; 2.60.40.10:FF:000469; Mast/stem cell growth factor receptor; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR042495; PDGFRL.
DR PANTHER; PTHR15360; PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE; 1.
DR PANTHER; PTHR15360:SF4; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF25305; Ig_PDGFR_d4; 1.
DR PIRSF; PIRSF000615; TyrPK_CSF1-R; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Receptor {ECO:0000313|EMBL:ETE64111.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 95..186
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 293..386
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE64111.1"
SQ SEQUENCE 453 AA; 50537 MW; 8B1FCF4337B5610B CRC64;
MRHAIPTSFG REDSDALIIC PVTDPDVSNF TLKRCRSKPL PENMTLVPDP QKGIIIKHVQ
RSFLGCYRCV AQQDGVEKSS KDITLVVRPV HKSLPSITLS KTNQLLKEGE EFEVTCTIRD
IDSFLQTNWI FQGNANLSSK SKNVRDYEYE QKLRLSIRSV GVNDSGAFTC QATNAFGTSN
VTVTLNVIGK GYVSLSTSTN TTLYVNDGEN LGLVVMYEAY PKPEEEMWLY MNETLQNSSD
HYVRVTNIDK NSYSSELHLT RLKEIEGGLY TFFVSNSDAN SSITFNVYVN TKPEIVTSER
LSNGMLLCVA TGYPAPTISW YVCPATEQRC PDSPNVSPVN VKTKYKDSTF SSFGKIIVES
TIDTSMFKSN STITCEASNT IDRRSAFFNF AIKGNFVSYF GNRIHDATNE YMDMKPGVSQ
VVHAKTTKRL GNLEKKGGNF CSEIVDICLH MAS
//
