GenomeNet

Database: UniProt
Entry: W0DP94
LinkDB: W0DP94
Original site: W0DP94 
ID   W0DP94_9GAMM            Unreviewed;       548 AA.
AC   W0DP94;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   02-JUN-2021, entry version 40.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AHE99077.1};
GN   ORFNames=THITH_13335 {ECO:0000313|EMBL:AHE99077.1};
OS   Thioalkalivibrio paradoxus ARh 1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Thioalkalivibrio.
OX   NCBI_TaxID=713585 {ECO:0000313|EMBL:AHE99077.1, ECO:0000313|Proteomes:UP000005289};
RN   [1] {ECO:0000313|EMBL:AHE99077.1, ECO:0000313|Proteomes:UP000005289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARh 1 {ECO:0000313|EMBL:AHE99077.1,
RC   ECO:0000313|Proteomes:UP000005289};
RG   DOE Joint Genome Institute;
RA   Muyzer G., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA   Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA   Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0007829|PDB:5F75}
RP   X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS) IN COMPLEX WITH COPPER.
RA   Tsallagov S.I., Polyakov K.M., Tikhonova T.V., Trofimov A.A.,
RA   Shabalin I.G., Popov A.N., Popov V.O.;
RT   "Thiocyanate dehydrogenase from Thioalkalivibrio paradoxus.";
RL   Submitted (DEC-2015) to the PDB data bank.
RN   [3] {ECO:0007829|PDB:5OEX}
RP   X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 82-548.
RA   Tikhonova T.V., Sorokin D.I., Tsallagov S.I., Polyakov K.M., Trofimov A.A.,
RA   Shabalin I.G., Khrenova M.G., Muyser G., Rakitina T.V., Popov V.O.;
RT   "Discovery and characterization of a novel copper containing enzyme
RT   - THIOCYANATE DEHYDROGENASE.";
RL   Submitted (JUL-2017) to the PDB data bank.
RN   [4] {ECO:0007829|PDB:6G5M}
RP   X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).
RA   Polyakov K.M., Tsallagov S.I., Tikhkonova T.V., Popov V.O.;
RT   "The structure of thiocyanate dehydrogenase from Thioalkalivibrio paradoxus
RT   complex with CU(I) ions.";
RL   Submitted (MAR-2018) to the PDB data bank.
RN   [5] {ECO:0007829|PDB:6G50, ECO:0007829|PDB:6I3Q}
RP   X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 82-548.
RX   PubMed=32094184; DOI=10.1073/pnas.1922133117;
RA   Tikhonova T.V., Sorokin D.Y., Hagen W.R., Khrenova M.G., Muyzer G.,
RA   Rakitina T.V., Shabalin I.G., Trofimov A.A., Tsallagov S.I., Popov V.O.;
RT   "Trinuclear copper biocatalytic center forms an active site of thiocyanate
RT   dehydrogenase.";
RL   Proc. Natl. Acad. Sci. U.S.A. 117:5280-5290(2020).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP007029; AHE99077.1; -; Genomic_DNA.
DR   RefSeq; WP_006748988.1; NZ_CP007029.1.
DR   PDB; 5F75; X-ray; 2.00 A; A/B/C/D=1-548.
DR   PDB; 5OEX; X-ray; 2.00 A; A/B/C/D=82-548.
DR   PDB; 6G50; X-ray; 1.65 A; A/B/C/D=82-548.
DR   PDB; 6G5M; X-ray; 2.31 A; A/B/C/D=82-548.
DR   PDB; 6I3Q; X-ray; 1.45 A; A/B/C/D=1-548.
DR   PDB; 6SJI; X-ray; 1.80 A; A/B/J/K=82-548.
DR   PDB; 6UWE; X-ray; 1.60 A; A/B/C/D=82-548.
DR   PDBsum; 5F75; -.
DR   PDBsum; 5OEX; -.
DR   PDBsum; 6G50; -.
DR   PDBsum; 6G5M; -.
DR   PDBsum; 6I3Q; -.
DR   PDBsum; 6SJI; -.
DR   PDBsum; 6UWE; -.
DR   SMR; W0DP94; -.
DR   EnsemblBacteria; AHE99077; AHE99077; THITH_13335.
DR   KEGG; tti:THITH_13335; -.
DR   HOGENOM; CLU_542826_0_0_6; -.
DR   OrthoDB; 214892at2; -.
DR   Proteomes; UP000005289; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR011048; Haem_d1_sf.
DR   InterPro; IPR006311; TAT_signal.
DR   InterPro; IPR019546; TAT_signal_bac_arc.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   SUPFAM; SSF51004; SSF51004; 1.
DR   TIGRFAMs; TIGR01409; TAT_signal_seq; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:5F75, ECO:0007829|PDB:5OEX};
KW   Copper {ECO:0000256|ARBA:ARBA00023008, ECO:0007829|PDB:5F75};
KW   Metal-binding {ECO:0007829|PDB:5F75};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   METAL           103
FT                   /note="Copper 1"
FT                   /evidence="ECO:0007829|PDB:5F75"
FT   METAL           135
FT                   /note="Copper 1; via tele nitrogen"
FT                   /evidence="ECO:0007829|PDB:5F75"
FT   METAL           206
FT                   /note="Copper 2; via tele nitrogen"
FT                   /evidence="ECO:0007829|PDB:5F75"
FT   METAL           314
FT                   /note="Copper 2"
FT                   /evidence="ECO:0007829|PDB:5F75"
FT   METAL           381
FT                   /note="Copper 2; via tele nitrogen"
FT                   /evidence="ECO:0007829|PDB:5F75"
FT   METAL           528
FT                   /note="Copper 1; via pros nitrogen"
FT                   /evidence="ECO:0007829|PDB:5F75"
SQ   SEQUENCE   548 AA;  59929 MW;  D29437D1DA295F58 CRC64;
     MSNSDHIDGK DLSEPNIAAE TAEGSVEDTG ASESRRKFLK TVGIGTGAAF AATAAAPFMP
     ESVRGLVTQD AQAQIFGRSG SKYVKVQDFY DQLGKYVLVA PGKFSGTVAA TDLSTGWTMA
     WLAAWNYGDT CPIMHHMAAF PSPDPYKEFE FVVNTQGGKN LFIYGVPVTV EDPGEGMKIY
     RIKYDGTRMN LQRDAAEVSG LGLGVHVTIT PEADGYAVGD GQKDICAEFD RETDMVRYAW
     AFDWDPNVKD LKRAWLDGGT MTIKRLKPTL PGGRYDLQGS KGNKIDWELV PGGELAIEDG
     KVSGDRPLHS VANDALVFDP RGKWAVASMR LPGVCVVFDR ENQVPVAVLA GPKGTPSQFQ
     LVKVDDDTWT VDIPEVISAG HQAGFSPDGQ SFLFMNSLRQ NNIMVWDSSN HDDPTTWEKK
     AVVESPDWRG AYPNTFHMVF TPDAKKIYVT MWWPSPTPNG IAVIDAVNWE VLKEVDLGPD
     MHTLAITYDG KFVVGTLSGY QNTASAIVVM ETETDEVLGF LPSPMGHHDN VIVPRTLEDL
     RISRSTTT
//
DBGET integrated database retrieval system