ID W6QFY3_PENRF Unreviewed; 645 AA.
AC W6QFY3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 18-JUN-2025, entry version 40.
DE SubName: Full=BRCT domain {ECO:0000313|EMBL:CDM35305.1};
GN ORFNames=PROQFM164_S04g000186 {ECO:0000313|EMBL:CDM35305.1};
OS Penicillium roqueforti (strain FM164).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM35305.1, ECO:0000313|Proteomes:UP000030686};
RN [1] {ECO:0000313|EMBL:CDM35305.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FM164 {ECO:0000313|EMBL:CDM35305.1};
RX PubMed=24407037; DOI=10.1038/ncomms3876;
RA Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT "Multiple recent horizontal transfers of a large genomic region in cheese
RT making fungi.";
RL Nat. Commun. 5:2876-2876(2014).
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DR EMBL; HG792018; CDM35305.1; -; Genomic_DNA.
DR AlphaFoldDB; W6QFY3; -.
DR STRING; 1365484.W6QFY3; -.
DR OMA; GMKIWAI; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000030686; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030686};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 587..636
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 347..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 522..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..386
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..556
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 72669 MW; 07562FB651BC2F36 CRC64;
MATVFVPPSP RNSMAMATRR PLANVPNATN SPHRAGLLPV KRARSTQTEI PYGQPPPKKQ
LIESMQYESR SATCQTTNTD SKLFARRSNN SNPSAFEKRL VAAREKERQP QVKHMRVEKA
PADTMDSIRQ WQRHYRKAFP QFVFYFDSIP EDVRRRFSRQ VTALGAREEK FFSRLVTHVV
TSRAIPPESA TPAEPESTVD ARNRDSNVLT VNPSLIERNG DNHLHASLKT ETRRDQGTMD
ILQRARQMGM KIWALEKLQR MITTINDSDI AAQYEQAARN KAAGGNAANA DLSRVLRQEL
LNGPSDRDPL ASLEMIMFKG PFVYIHDMNE KTKPVMVREY PRVARRQDGS WPQFRSAPLG
KCPFIDEPPS RKEYDRHRLR QIHKEKKAAS HAADGTRHAK PKAAAPVQAP ESVTTTEMAH
SQPSAKQEER VPPPIQNETQ KPLDETHERK SSESFVPPHF PRTGPFYAGC EPAASGIQPS
NMTSAIRSQM ISSTAAAPGA KAGLSKEVHG LKRKVLEKGT GGFTAGSMAA PQRRGDGFTT
VTTKNNTNPP GKPNVVINEN EAKQSEVAGS KRQREDKDEQ KKSERRRDPK PGYCENCRDK
FDDFEEHTLT RKHRRFAANS TNWAELDALL SEIQRPLKDE YEYDE
//
