ID W9Y4J0_9EURO Unreviewed; 544 AA.
AC W9Y4J0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 28-JAN-2026, entry version 37.
DE SubName: Full=Sphingosine kinase {ECO:0000313|EMBL:EXJ77354.1};
GN ORFNames=A1O3_09580 {ECO:0000313|EMBL:EXJ77354.1};
OS Capronia epimyces CBS 606.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182542 {ECO:0000313|EMBL:EXJ77354.1, ECO:0000313|Proteomes:UP000019478};
RN [1] {ECO:0000313|EMBL:EXJ77354.1, ECO:0000313|Proteomes:UP000019478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 606.96 {ECO:0000313|EMBL:EXJ77354.1,
RC ECO:0000313|Proteomes:UP000019478};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia epimyces CBS 606.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ77354.1}.
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DR EMBL; AMGY01000010; EXJ77354.1; -; Genomic_DNA.
DR RefSeq; XP_007737864.1; XM_007739674.1.
DR AlphaFoldDB; W9Y4J0; -.
DR STRING; 1182542.W9Y4J0; -.
DR GeneID; 19173664; -.
DR eggNOG; KOG1116; Eukaryota.
DR HOGENOM; CLU_013399_0_1_1; -.
DR OrthoDB; 3853857at2759; -.
DR Proteomes; UP000019478; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0001727; F:lipid kinase activity; IEA:UniProtKB-ARBA.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EXJ77354.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019478};
KW Transferase {ECO:0000313|EMBL:EXJ77354.1}.
FT DOMAIN 140..279
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 544 AA; 59832 MW; 4F3E220174355FDB CRC64;
MAASRPHDLD PFSDHAAVQD EREAIAESTL AVGRNATLTL GTDTVIVLDE GLRKATGFNC
FGLWPQRTTS TRSIPYFNVL WAEIVKDDLT IRYAKPESKS ADSPVHVAYI NYTLDSSAYT
QERASRWVHR LLDRAYGQSR RNKRIKLLIN PFGGAGKASK LYTREIEPIF AAARCEVDVE
HTTHAGHAVE ICERLDINAY DVVASASGDG LPHECINGLA KKPNAAEALR KVAIVQLPCG
SGNAMSWNLN GTGECSTAAL CIVKGVRTPL DLVSVTQGDK RTISFLSQSL GIVAESDLGT
ENLRWMGGTR FTFGFLVRLL GKTVYPCEIA MKTAIDDKQE IRRHYARQMV RREQENPLLQ
SELDGPLDTS TNLGLPPLQY GTINDPLPTD AGWTPLTPYP TLGNFYCGNM TMMAADMPFF
PASLPSDGLL DLVTIDGDIG RMKSIGLLLS VPKGTFFDKD CVNTYKVQAV RVIPRYGPGV
EDAQHLQHKK KTGYFSVDGE KMPFEPFQLE VHRGLGTVLS RHVGRYEAIG PKGWQDIEVG
RANS
//
