ID X0CYU5_FUSOX Unreviewed; 682 AA.
AC X0CYU5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 02-APR-2025, entry version 47.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=FOQG_08975 {ECO:0000313|EMBL:EXK87637.1};
OS Fusarium oxysporum f. sp. raphani 54005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089458 {ECO:0000313|EMBL:EXK87637.1, ECO:0000313|Proteomes:UP000030663};
RN [1] {ECO:0000313|EMBL:EXK87637.1, ECO:0000313|Proteomes:UP000030663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=54005 {ECO:0000313|EMBL:EXK87637.1,
RC ECO:0000313|Proteomes:UP000030663};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum PHW815.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH658382; EXK87637.1; -; Genomic_DNA.
DR AlphaFoldDB; X0CYU5; -.
DR HOGENOM; CLU_442142_0_0_1; -.
DR OrthoDB; 111588at110618; -.
DR Proteomes; UP000030663; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20335; BRcat_RBR; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030663};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 416..661
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT COILED 62..131
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 682 AA; 77750 MW; F27E3AD4AD5ED114 CRC64;
MSSFQKIQSD IHASQSQLPH PIHAIAKHIP RLSELSWFGC NDELSEPSIS AECITDILAN
NFNQMHQQIE DLQGTINDLL DENKALKVKM STKIEESISL LQKICKMNID IQTNLNEKRA
MADEVDKLRA QIAGRPLGML ETTQRGIIIS KLLSRSQSIY ENYNAIQEEG LPNSKIENAA
SDLKSPLDSI LSADEARRLF HSFQDWFDEQ DLDSISLRRC SVCHKMRFEQ ATPNISYPLV
DEFSTSLQRP ITCRTSVCLV CYLESVLKSI QGLPETWWEM SGSTVLIPCP CGACSADIAI
QDHGTLQRLL RLTKVQDADE KLRIYDTAQH LVSVLDSLDP QPTIEARQVA KRLHQHLTSN
GIMKPLLDLT ISELHTLEEG VPHDVNSSLV QLLELDGTDQ VLRVPIFTQL LQREQSPVEC
SICTEPVYDL IGEALNKWDT ICGDYDGDWK WKVLPFPRKL EQRCSHTVDF CTECLENYIE
AQLDQHGRAG CHLLTCPSSD CGRRLEYDEV KLYARQEAFS KYDKYLTLEA LSNLPSFRWC
LAKNCSYGQI HDLIESNHVS CEECGCEMCF EHQTKWHNDL TCEEFDSMEE NGDPRFHETR
DWVNANTKQC PSCGINTQKG PGCFHMTCTL CRHEFCWECL ASWSDIMPRS GQHNQSAHRD
DCYFRSSNRQ PTQVTGEHIP IR
//
