KEGG   Vulpes lagopus (Arctic fox): 121489860
Entry
121489860         CDS       T07435                                 
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
vlg  Vulpes lagopus (Arctic fox)
Pathway
vlg04310  Wnt signaling pathway
vlg04390  Hippo signaling pathway
vlg04519  Cadherin signaling
vlg04550  Signaling pathways regulating pluripotency of stem cells
vlg04810  Regulation of actin cytoskeleton
vlg04934  Cushing syndrome
vlg05010  Alzheimer disease
vlg05022  Pathways of neurodegeneration - multiple diseases
vlg05165  Human papillomavirus infection
vlg05200  Pathways in cancer
vlg05206  MicroRNAs in cancer
vlg05210  Colorectal cancer
vlg05213  Endometrial cancer
vlg05217  Basal cell carcinoma
vlg05224  Breast cancer
vlg05225  Hepatocellular carcinoma
vlg05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:vlg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    121489860 (APC)
   04390 Hippo signaling pathway
    121489860 (APC)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    121489860 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    121489860 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    121489860 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121489860 (APC)
   05206 MicroRNAs in cancer
    121489860 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    121489860 (APC)
   05225 Hepatocellular carcinoma
    121489860 (APC)
   05226 Gastric cancer
    121489860 (APC)
   05217 Basal cell carcinoma
    121489860 (APC)
   05213 Endometrial cancer
    121489860 (APC)
   05224 Breast cancer
    121489860 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    121489860 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121489860 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    121489860 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    121489860 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:vlg01009]
    121489860 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:vlg03036]
    121489860 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:vlg04812]
    121489860 (APC)
Protein phosphatases and associated proteins [BR:vlg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     121489860 (APC)
Chromosome and associated proteins [BR:vlg03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    121489860 (APC)
Cytoskeleton proteins [BR:vlg04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     121489860 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u15 APC_u9 SAMP APC_N_CC Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS
Other DBs
NCBI-GeneID: 121489860
NCBI-ProteinID: XP_041609196
Position
4:complement(59984650..60106659)
AA seq 2862 aa
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
RGFVNGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRVTRIQQIEKDILRIRQLLQSQAT
EAERSSQSKHEAGSHEAERQNEGQGVGEINMATSGSAQGSAARMDHETASVLSSSSTHSA
PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
WEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGRKATRGISSQ
ELGQGLSGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSM
KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE
STLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNV
SSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMG
AVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEA
ELDAQHLSETFDNIDNLSPKASHRNKQRHKPNLYGDYVFDTNRHDDNRSDNFNAGNMTVL
SPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGISLGNYHPATENPGTSSKRGLQIST
TAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCGTDERNTLRRSSTAHTHANTYSFTKSEN
SNRTCPVPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPA
DLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQ
SEQRQSRSQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGASGSEMNRVGSNHGIN
QNVNQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKHHVDQPIDYSLK
YATDIPSSQKPPFSFSKNSSGQSAKTEHLSASSENTSTPSSSAKRQTQHHPSSAQSRNGQ
TPKANSCKVPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCDPAPQEAESANTL
QRAEIKENSGTRTTEDAVSEVPAASPHIRTKSSRLQASGLSAESTRHKAVEFSSGAKSPS
KSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSD
LPDSPGQTMPPSRSKTPPPPPQTVQTKREVPKNKASAAEKRESGPKQAAVNAAVQRVQVL
PDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQP
EEANENQEKEPEKPTDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTAPKLP
PPVARKPSQLPVYKLLPSQNRLQAQKHVSFTPGEDMPRVYCVEGTPINFSTATSLSDLTI
ESPPNELAAGEGVRAGAQPSEFEKRDTIPTEGRSTDEAQRGKAPAVTIPELDDSKTEEGD
ILAECINSAMPKGKSHKPFRVKKIMDQVQQASVSSSGTNKNQLDGKKKKPTSPVKPIPQS
AEYRTRVRKHTDSKNNVNAERTFSDNKDSKKQNLKNNSKDFNDKLPNNEDRVRGSFTFDS
PHHYTPIEGTPYCFSRNDSLSSLDFEDDDVDLSREKAELRKGKENKDSEAKVPSHTEPTS
NQQSANKTQAVTKHPINRGQSKPVLQKQPTFPQSSKDLPDRGAATDEKLQNFAIENTPVC
FSRNSSLSSLSDIDQENNNNKENEPLKEAEPPDSQGEPSKPQASGYAPKSFHVEDTPVCF
SRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDTEKHSPRNMSGILAEDLTLDLK
DIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSG
ISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESENKGIKGGKKVYKSLITG
KIRSNSEVLSQMKQPLQANMPSLSRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSP
SEGQTATTSPRGTKPSVKSELSPVTRPAPQPAGANKGPSRSGSRDSTPSRPAQQPLSRPM
QSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLSKQ
TGLSKNGSSIPRSESASKGLNQMSNSNGSNKKVELSRMSSTKSSGSESDRSERPVLVRQS
TFIKEAPSPTLRRKLEESASFESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLSAHPSIQS
GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRV
STWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQMKENQVSTKGTWRKIKENDIS
PTNSTSQTTSSGAANGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNMPP
VIDTVLEKGNPNAKDAKDNQGKPSVGNGSGPVRAVGLENRLNSFIQVEAPDQKGTEAKPG
PSNPVPAPEANESCAAERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADGTSAR
PSQIPTPVATATKKRDSKTDGAESGGTQSPKRHSGSYLVTSV
NT seq 8589 nt   +upstreamnt  +downstreamnt
atggctgcagcttcatatgatcagttgttaaagcaagttgaggcactgaagatggagaac
tcaaatcttcgacaagagctagaagataattccaatcatcttacaaaactggaaactgag
gcatctaatatgaaggaagtacttaaacaactacaaggaagtattgaagatgaagctatg
gcttcttctggacagattgacttattagagcgtctcaaagaacttaacttagatagcagt
aatttccctggagtgaaactacggtcaaaaatgtccctccgttcttatggaagccgcgaa
ggatctgtatctagtcgttcgggagagtgcagtcctgttcctatgggttcatttccaaga
agagggtttgtaaacggaagcagagagaatactggttatttagaggaacttgagaaagag
agatcattacttcttgctgatcttgacaaagaagaaaaggaaaaagattggtattatgct
caacttcagaatctcactaaaagaatagatagtctccctttaactgaaaatttttcctta
caaacagatatgaccagaagacaattagaatatgaagcaaggcaaatcagagttgcaatg
gaagaacaactaggtacttgccaggatatggaaaaaagagcgcagcgaagagtaaccaga
attcaacaaatagagaaggacatacttcgtatacgacagcttttacagtcccaagcaaca
gaagcagagagatcatctcagagcaagcatgaagccggctcacatgaagctgagcggcag
aatgaaggtcaaggagtgggagaaatcaacatggcaacttctggtagtgctcagggttca
gctgcacgaatggatcatgaaacagcaagcgttttgagttctagtagcacacactctgct
cctcgaaggttgacaagtcatctgggcaccaaggtggaaatggtgtattcattgttgtca
atgcttggtactcatgataaggatgatatgtcgcgaactttgctagctatgtctagctcc
caagacagctgtatatccatgcgacagtctggatgtcttcctctcctcatccagctttta
catggcaatgacaaagactctgtgttgttgggaaattcccggggcagtaaagaggctcgg
gccagggccagtgcagcacttcacaacatcattcactcacagcctgatgacaagagaggc
aggcgtgaaatccgagtccttcatcttttggaacagatacgagcttactgtgaaacctgt
tgggagtggcaggaagcccatgaacaaggcatggaccaggacaaaaatccaatgccagct
cctgttgaacatcagatctgtcctgctgtgtgtgttctaatgaaactttcatttgatgaa
gagcatagacatgcaatgaatgaacttggtaggaaggctacccggggcatttcatcacag
gagctagggcaggggctttcagggggactacaggccattgcagaattattgcaagtggac
tgtgaaatgtatgggctaactaatgaccactacagtattacattaagacgatatgctgga
atggctctgacaaacttgacttttggagatgtagccaacaaggctacactctgctctatg
aaaggctgcatgagagcacttgtggcccaactaaaatctgaaagtgaggacttacagcag
gttattgcaagtgttttgaggaatttgtcttggcgagcagatgtaaatagtaaaaagaca
ttgcgtgaagttggaagtgtgaaagcattgatggaatgtgctttggaagttaaaaaggaa
tcaaccctcaaaagcgtattgagtgccttatggaatttgtcagcacactgcactgagaat
aaagctgatatatgtgctgtggatggtgcacttgcgttcctggttggcactctcacttac
cgaagccagacaaatactttagccattatcgaaagtggaggtgggatattacggaatgtg
tccagcttgatagctacaaacgaggaccacaggcaaatcctaagagagaacaactgcctg
caaaccttattgcaacacttgaaatctcacagtttgacaatagttagtaatgcatgtgga
accttgtggaatctctcagcaagaaatccaaaagaccaagaagcattatgggacatgggg
gcagtcagcatgctcaagaacctcattcattcaaagcacaaaatgattgctatgggaagt
gccgcagctttaaggaatctcatggctaatagacctgcaaagtataaggatgccaatatt
atgtctcctggttcaagcttgccatctcttcatgtcaggaaacaaaaagccctagaagca
gaattagatgctcagcatttatcagaaacttttgacaatattgacaatttaagtcccaag
gcatctcatcgtaacaagcaacgacacaagccaaatctgtatggtgactatgtttttgac
accaatcgacatgatgataataggtcagacaattttaatgctggaaatatgactgtcctt
tcaccgtatttaaatactacagtgttgcccagctcttcttcatcaagaggaagtttagac
agttctcgttctgaaaaagatagaagtttggagagagaacgaggaattagcttaggcaac
taccacccagcaacggaaaatccaggcacgtcttcaaagcgaggtttgcagatttccacc
acggccgcccagattgccaaagtcatggaagaagtatcagccattcacacctcccaggaa
gacagaagttctgggtctaccactgagttacactgtgggacagatgagaggaacacacta
agaagaagctcgactgcccacacacatgcaaacacatacagcttcacgaagtcagaaaat
tcaaacaggacgtgtcctgtgccttatgctaaattggaatacaagagatcttcaaatgat
agtttaaacagtgtcagtagtagtgatggttatggcaaaagaggtcagatgaagccttcc
attgaatcctattctgaagatgacgaaagtaaattttgcagctatggtcaatacccagct
gacctagcccataaaatacatagtgcaaatcatatggatgacaacgatggagagctagat
acacccataaattatagtcttaagtattcagacgagcagttgaactctggaaggcaaagc
ccctcacagaatgaaagatgggcaagacccaagcatataatagaagacgaaataaaacaa
agtgagcaaagacaatcaagaagtcaaagcacaacttaccccgtatacactgagagcact
gatgataaacacctcaagttccagccacattttggacagcaggaatgtgtttccccatat
aggtcaagaggagccagtggttcagaaatgaatcgagtaggttctaatcatggaattaat
caaaacgtaaaccagtctttgtgtcaggaagatgactatgaagacgataagccaaccaac
tatagtgaacgttactctgaggaagagcaacacgaggaagaagaaagaccaacaaattat
agcataaagtacaatgaagaaaaacatcacgtggatcagcctattgattatagtttaaaa
tatgccacagacattccttcctcacagaaaccaccattttcattctcaaagaattcctct
gggcaaagcgctaaaactgaacacctctctgcaagcagtgagaatacatccacgccttca
tccagtgccaagaggcagactcagcaccatcccagctcagcacaaagtagaaatggccag
accccaaaagccaactcctgcaaagttccctctatcaaccaggaaacgatacagacatac
tgtgtagaggacaccccgatttgtttctcgcgttgcagttcactatcctctctgtcctca
gctgaagatgagatcggatgtgacccagcaccgcaggaggcagagtcagctaatacccta
caaagagcagaaatcaaagaaaacagtgggacaaggacaacagaagatgctgtgagtgag
gttccagcagcgtcaccgcacatcagaaccaaatccagcagacttcaggcttctggttta
tcggcagagtcaaccaggcacaaagctgttgaattttcttcaggggccaaatctccatca
aaaagtggtgctcagactcctaaaagtccaccagagcactatgttcaggagactccgctc
atgtttagcaggtgtacgtcagtcagttcgctcgacagttttgagagtcgttcaattgcc
agctctgttcagagcgaaccctgcagtggcatggtgagtggcattataagccccagtgac
cttccagatagcccaggacaaaccatgccgccaagcaggagtaaaacccctcctcctccc
cctcagacagttcagactaagcgagaggtccctaaaaacaaagcctctgctgccgagaag
agagagagcggccctaagcaagctgctgtgaatgctgcagttcagagagtccaggttctt
ccagatgctgacaccctattgcattttgccacagaaagtactccggatggattttcttgt
tcatccagcctgagtgctctgagccttgatgagccatttatacagaaagacgtggaatta
agaataatgcctccagttcaggaaaacgacaatgggaatgaaactgagtctgagcagcct
gaagaagcaaatgagaaccaggaaaaagagcccgaaaagcctactgattctgaaaaagac
ctgttagacgactcagatgatgatgatattgaaatacttgaagagtgtattatttctgcc
atgccaacaaaatcttcacgcaaagccaaaaaaccagcccagactgctccaaaattacct
ccccctgtggcaaggaagccaagtcaactccccgtctacaaactccttccctcgcaaaac
aggttacaggcgcaaaagcatgttagcttcaccccaggagaggatatgccacgggtgtac
tgtgtcgaagggacgcctatcaacttctccacagctacgtctctaagcgatctgacaata
gaatctcctccaaatgagttagctgctggagaaggggttagagccggggcacagccaagt
gaatttgagaaacgagataccattcctacagaaggcagaagtacagacgaggctcaaaga
ggaaaagccccggcagtgactatacctgagctggatgacagtaaaacagaagagggggat
attcttgcagagtgcattaattctgctatgcccaaaggaaaaagtcacaagcctttccgt
gtgaagaagataatggaccaggtccagcaggcgtctgtgtcttcatctggaactaacaaa
aatcagttagatggcaagaaaaagaaacctacttcaccagtaaaacctataccacagagc
gccgaatacaggacacgtgtaagaaaacacacagactcgaaaaataatgtaaatgctgaa
agaactttctcagacaataaagattcaaagaaacagaacttgaaaaataattccaaggac
ttcaatgataagctaccaaataacgaagatcgagtcagaggaagttttactttcgattca
cctcatcactacacgcccattgaaggaactccgtactgtttttcacgaaatgattctttg
agttctctagattttgaggatgatgatgttgacctttccagggaaaaggctgaattaaga
aaagggaaagaaaataaagactcagaagctaaagtccccagccacacagaaccaacctct
aaccaacaatctgctaataaaacccaggctgttacaaaacaccccataaatcgaggtcag
tctaaacccgtgctgcagaagcagcccacgtttccacagtcctctaaagacctaccagac
agaggggcagcaactgatgagaaattgcagaattttgctatcgaaaatactccagtgtgc
ttttctcggaactcctctctaagttctcttagtgacattgaccaagaaaacaacaataac
aaagaaaatgaacctcttaaagaggccgagccccctgactcccagggagaacccagtaaa
cctcaggcatcgggttacgcacctaaatcctttcacgttgaagacactcctgtttgtttc
tcgagaaacagttctctcagttctctaagcattgattctgaagacgacctgttgcaggag
tgtataagttctgcaatgccaaaaaagaaaaagccttcaagactcaagggtgatactgaa
aagcatagtcccagaaacatgagcggcatattagcagaagacttgacacttgatttgaaa
gatatacagagaccagattcagaacatggtttatccccagattcagaaaattttgattgg
aaagctattcaggaaggtgcaaattccatagtaagtagtttacatcaagctgccgctgct
gcctgtttgtctagacaagcttcatccgactcagattccatcctttcactgaaatcggga
atcagtctggggtcaccatttcatcttacacccgaccaagaggaaaaaccctttacaagt
aataagggcccacgaattctaaaacccggggagaagagtacattggaaactaaaaagata
gaatctgaaaataaaggaatcaaaggaggcaaaaaagtttataaaagtttaataactgga
aaaattcgatctaattcggaggttttaagccaaatgaaacagccccttcaagcaaacatg
ccttcgctctctcgaggcaggaccatgattcatattccaggagttcgaaacagctcttca
agtacaagtccggtttctaaaaaaggtccaccccttaagactccagcctccaaaagtccc
agtgagggtcagacagccaccacttctcctagaggaaccaaaccatccgtgaagtcagaa
ttaagccctgtgaccaggccggccccccagccagctggggcaaataaagggccatctaga
tcaggatcgagagattccactccttcgagacctgcccaacagccattaagtagacccatg
cagtctccagggcggaactccatttctcctggtaggaatggaataagtcctcctaacaaa
ttatctcagttgccaaggacttcatcccctagtactgcatcgaccaagtcctccgggtct
gggaagatgtcctatacgtctccaggcagacagatgagtcagcagaaccttagcaaacaa
acgggtttatccaagaatggcagtagtatcccaagaagtgagtctgcctccaaaggactg
aatcagatgagtaatagcaatggatccaacaaaaaggtggagctttctagaatgtcttca
actaaatcgagtggaagtgaatccgataggtcagagagacctgtattagtacgccagtca
actttcatcaaagaagctccaagcccaaccctaaggagaaaattggaggaatctgcttca
tttgaatctctctctccatcttctagaccagattctcccactaggtcccaggcacagact
ccagttttaagcccttcccttcctgatatgtctctgtccgcacatccatccattcagtct
ggtgggtggcgcaaactcccacctaatctcagtcctaccatagagtacaatgacggaaga
ccagcaaagcgccatgatattgcacgctcccattctgaaagtccttcgagacttccaatt
aataggtcaggaacctggaaacgggagcacagcaagcattcgtcatcccttcctcgagta
agcacttggagaagaactggaagttcatcctccattctttctgcttcatcggaatccagt
gaaaaagcaaaaagtgaggatgaaaaacacgtgaactcgatttcaggaaccaaacaaatg
aaggaaaaccaagtatccacaaaaggaacatggagaaaaataaaagaaaatgatatttct
cccacaaatagtacctctcagaccacttcctcaggtgctgcaaatggtgctgaatcaaag
actctaatttatcaaatggcacctgctgtttctaaaacagaggatgtttgggtgagaatt
gaggactgtcccattaacaaccctcgatccgggagatccccaacaggaaacatgccccct
gtgattgacactgttttggaaaaggggaacccaaacgctaaagatgcaaaagataatcag
ggaaaaccaagtgtgggtaatggcagtggccccgtacgcgccgtgggtttggaaaaccgc
ctgaactcctttatccaggtagaggcccctgaccagaagggaacggaggcaaaaccggga
ccgagtaaccctgtccctgcaccagaggcgaacgagagttgtgcagccgagcgcaccccg
ttcagctccagcagctcaagcaagcacagttcccccagcgggaccgtcgctgccagagtg
accccctttaattacaacccgagccctcggaagagcagcgcggacggcacgtcagcccgg
ccgtcccagatccccacgccggtggccaccgccacgaagaaacgggattccaagactgac
ggcgccgagtccggcggaacccagagccctaagcgccattccgggtcttacctcgtgacg
tccgtgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (18)   
   Pfam (18)   
All databases (34)   

Download RDF
DBGET integrated database retrieval system