KEGG   Xiphophorus hellerii (green swordtail): 116733615
Entry
116733615         CDS       T07363                                 
Symbol
plcb4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
xhe  Xiphophorus hellerii (green swordtail)
Pathway
xhe00562  Inositol phosphate metabolism
xhe01100  Metabolic pathways
xhe04020  Calcium signaling pathway
xhe04070  Phosphatidylinositol signaling system
xhe04081  Hormone signaling
xhe04082  Neuroactive ligand signaling
xhe04261  Adrenergic signaling in cardiomyocytes
xhe04270  Vascular smooth muscle contraction
xhe04310  Wnt signaling pathway
xhe04371  Apelin signaling pathway
xhe04540  Gap junction
xhe04621  NOD-like receptor signaling pathway
xhe04912  GnRH signaling pathway
xhe04916  Melanogenesis
Module
xhe_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:xhe00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    116733615 (plcb4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    116733615 (plcb4)
   04371 Apelin signaling pathway
    116733615 (plcb4)
   04020 Calcium signaling pathway
    116733615 (plcb4)
   04070 Phosphatidylinositol signaling system
    116733615 (plcb4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    116733615 (plcb4)
   04081 Hormone signaling
    116733615 (plcb4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    116733615 (plcb4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    116733615 (plcb4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    116733615 (plcb4)
   04916 Melanogenesis
    116733615 (plcb4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    116733615 (plcb4)
   04270 Vascular smooth muscle contraction
    116733615 (plcb4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xhe04131]
    116733615 (plcb4)
Enzymes [BR:xhe01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     116733615 (plcb4)
Membrane trafficking [BR:xhe04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    116733615 (plcb4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    116733615 (plcb4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 116733615
NCBI-ProteinID: XP_032440273
Position
15:complement(17861200..17927729)
AA seq 1228 aa
MTKSYEFNWQKHLPEFMQEGASFDRFDEDPYLFEPNCQMKVDEYGFFITWKSEGKEGQVL
ECSLINSIRVGAVPKDPKILSSFEAIGKTEADLEGCIICICSGTDLVNLSFMFMVAESPD
TARKWIEGLRSVIHNFKANNVCPMTCLKKHWMRMCFLTNVNGKIPVRGITRTFASGKTEK
GIFQALKDLGLPSGKNDEIEPSDFTFDIFYALTQKICPRTDIEELFKKINGNKTDYLTVD
QLVSFLNENQRDPRLNEILFPFYDPKRAMQIIEKYERDEELKKKGRMSSDGFCRYLMSDE
NAPVFLDRLELYQDMDQPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSDYPVILSFENHCSKIQQYKM
AKYCEELFGDLLLRQPLENYPMDPGHPLPSPNDLKRKILIKNKRLKPEVEQRQLEALKKH
MEAGETNTPAIIMGEENEDDAENGEKEAEDKDLNSEAPSILSEVTSDKETNSVSQSNAIS
SGKEEERSNSIKKVPDDEVTEISEATDATDISEASDQDNKKGGDVAEDSEEALIAQYKYE
SATTNIHPYLSAMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTNAIEFVNYN
KRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGCCGYLL
KPDFMRRSDRTFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGLPTDTIR
KEFRTRMVMNNGLNPAYNEEPFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAG
YRHISLRNEGNNPLSLPTVFCQIILKTYVPDGFGAIVDALSDPKKFLTIAEKRADQMKAL
GIDTNDIADVPNGSSKNDKKGKGKGDTGKASVTQQASSDMAQTSNSIQNNTNENKKDTAL
VPNVSIDDLKQMKSYLKLIKKQQKELNTLKKKHSKDQNAMQKAHCTQVDKMVSLHEKEKT
NLEKLLEKAIKKRGENNCQELKKETEDKIQTLTTDHKAKVKDITAQHTKEWSELISSHSN
EEREMKDSHVTQQCEHLKKLLSSVQDQQTLQLKVIHERQSKEMRANQAKMSMENSKAISQ
DKSIKNKAERERRVRELNSSNTKKFLDERKRLAMKHQKEMEQLEKNQREQLDKLEKHNEQ
LLKSHHANKQVQGQGHPADGEVGGGDGP
NT seq 3687 nt   +upstreamnt  +downstreamnt
atgacaaagtcctatgagttcaactggcagaagcacctgcctgagttcatgcaagaaggt
gcctccttcgacaggtttgatgaggacccatacctctttgagcccaactgtcagatgaag
gtggatgaatatggcttctttatcacatggaagagtgagggaaaggagggccaggttctc
gaatgttctcttatcaacagtatccgtgtcggtgccgtccctaaggacccaaagatcctg
tcctcattcgaggccataggaaagacagaggccgacctggagggatgcatcatctgcatc
tgcagtggcactgacctggtcaacctgagcttcatgttcatggtggcagagagccccgac
acagccaggaaatggattgagggtttgaggtcggtgatccacaactttaaggccaacaac
gtgtgtccaatgacatgcctcaagaaacattggatgaggatgtgtttcttgaccaatgtc
aacgggaagatccctgttagaggtatcacaagaacctttgcatcagggaagacagagaaa
gggatctttcaggctctgaaggatctaggtcttcccagtggaaagaatgacgagattgaa
ccctcagacttcacctttgacattttctacgcgctgacacagaagatctgccctcgcaca
gatatagaggagctcttcaagaaaatcaatgggaacaaaacagattatttaactgtagac
cagttagtcagctttctgaatgaaaaccaacgtgacccgaggttaaatgagattctgttt
ccattttacgaccccaaaagagccatgcagatcattgagaaatatgaaagggacgaagag
ctgaagaaaaaaggccgcatgtcgagtgacgggttctgtcgctacctaatgtcagacgaa
aatgctccggtgttcctggacagactagagctgtaccaagacatggatcagcctttggct
cattattttatcagctcctcccacaatacatacctgacaggaagacagtttggagggaag
tcatcagtggagatgtaccgccaggtccttctgtctggatgcagatgtgtggagctagac
tgctgggatggcaaaggggaggaccaggaacccatcattactcatggcaaggccatgtgc
acagacatcctgttcaaggatgtgatccaagcaatcaaggagacggcatttgtcacatct
gattatcctgttattttatcctttgaaaatcattgcagtaaaatacagcagtataagatg
gccaagtactgtgaggagctctttggcgaccttcttctcaggcagcctctggagaactac
ccaatggatcctgggcatcccttaccttcaccaaatgacctgaagagaaaaatcctaata
aagaataagcggttaaaacctgaagtggagcagaggcaacttgaagctttaaagaagcac
atggaggccggtgagaccaacactcctgctatcattatgggagaagagaatgaagacgat
gcagagaacggggaaaaagaagctgaagataaagatttgaattcagaggctcccagcatt
ctgtcagaagtcaccagtgacaaagagacgaacagcgtttcccagagtaacgccatcagc
tctggaaaagaggaagagcgcagcaacagcatcaaaaaggtacctgatgacgaggtcaca
gagatttctgaagcaacagacgccacagatatctctgaggcatctgatcaagacaacaag
aagggcggagatgtggcagaggactctgaggaggctctaatagcgcaatataaatatgag
tcagccaccacaaatatccacccgtatctctcagccatggtcaactatgcacagccggtg
aagttccagggttttgatgttgcagaagagaggaatatccaccacaacatgtcatccttt
aatgagtcagtgggcctgggctatctgaagaccaacgccatcgagtttgtcaactacaac
aagcgtcagatgagccgtatctaccccaaaggaggcagggtggactccagtaattacatg
cctcagatcttctggaacgcaggctgccagatggtctccctcaacttccagaccccagat
ctggccatgcagctgaaccaaggaaagtttgagtacaacggctgttgtgggtacctgctg
aagccagacttcatgcgtcggtcagacaggacgtttgaccctttctctgagacgccggtg
gatggcgtcattgcagcaacctgcagcgtccaggtgttctcaggacagtttctgtctgac
aaaaaaattggcacatacgttgaagtagatatgtacggcttgcccacggatacaattcgg
aaagagttccgcacacgcatggtgatgaacaatggactcaatccagcctacaacgaagag
ccctttgttttcagaaaggtaatcttaccagatctggcggtgctgcgcatcgcagtgtac
gacgacaacaacaagctgattggccaacgcatcctgcctctggacggcctgcaggctggc
taccgtcacatctccctgaggaacgaaggcaacaaccctctgtcgttgccgacagtcttc
tgccaaatcatcctcaagacctacgtgcccgacggcttcggagctattgtggatgctcta
tcagatccaaagaagtttttgaccatagcggagaagagagccgaccagatgaaggccctg
gggatcgacacgaatgacatagcagatgttcccaatggaagctcaaagaatgacaagaag
ggaaagggaaaaggagacacagggaaagccagtgtgacacaacaagccagctcagatatg
gcccagacctccaattctatccaaaacaacacaaacgagaacaagaaggatactgcgctt
gtgcctaatgtgagcattgatgacttaaagcaaatgaagagctacctaaagctgattaaa
aagcagcagaaggagctcaacactttaaagaagaaacactcaaaggatcaaaatgcaatg
cagaaagcccattgcactcaggtggataagatggtgtccctccatgaaaaggaaaagact
aatctggagaaactgttggagaaagccatcaagaaacgaggggagaacaactgtcaagag
ctgaagaaggagacagaagataagatccaaactctcaccacagatcataaagcaaaggtg
aaagacatcacagcacaacacactaaggagtggtcggagctgatcagtagtcacagcaac
gaagagcgcgagatgaaggacagtcatgttacccagcagtgtgagcatctcaagaagctc
ctttctagtgtccaggatcagcagaccctgcagctcaaagtcattcatgaaaggcaaagc
aaagagatgcgtgccaaccaggccaagatgtccatggaaaacagtaaagcaatcagccaa
gacaaaagtatcaaaaacaaggcagagcgagagaggagagtgcgggagttaaacagcagc
aacaccaagaagtttttggatgagaggaagaggttggctatgaaacatcagaaggagatg
gagcagctggagaaaaatcagagggagcagttggataaactggagaagcacaacgagcag
cttttgaaatcacaccatgcaaacaaacaggttcaaggccaaggacatccagcagatggt
gaagttggaggaggagatggaccgtag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (9)   
   Pfam (9)   
All databases (21)   

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