KEGG   Xenopus tropicalis (tropical clawed frog): 100487267
Entry
100487267         CDS       T01011                                 
Symbol
plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
xtr  Xenopus tropicalis (tropical clawed frog)
Pathway
xtr00562  Inositol phosphate metabolism
xtr01100  Metabolic pathways
xtr04020  Calcium signaling pathway
xtr04070  Phosphatidylinositol signaling system
xtr04081  Hormone signaling
xtr04082  Neuroactive ligand signaling
xtr04261  Adrenergic signaling in cardiomyocytes
xtr04270  Vascular smooth muscle contraction
xtr04310  Wnt signaling pathway
xtr04371  Apelin signaling pathway
xtr04540  Gap junction
xtr04621  NOD-like receptor signaling pathway
xtr04912  GnRH signaling pathway
xtr04916  Melanogenesis
Module
xtr_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:xtr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100487267 (plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    100487267 (plcb3)
   04371 Apelin signaling pathway
    100487267 (plcb3)
   04020 Calcium signaling pathway
    100487267 (plcb3)
   04070 Phosphatidylinositol signaling system
    100487267 (plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100487267 (plcb3)
   04081 Hormone signaling
    100487267 (plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100487267 (plcb3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    100487267 (plcb3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100487267 (plcb3)
   04916 Melanogenesis
    100487267 (plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100487267 (plcb3)
   04270 Vascular smooth muscle contraction
    100487267 (plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xtr04131]
    100487267 (plcb3)
Enzymes [BR:xtr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100487267 (plcb3)
Membrane trafficking [BR:xtr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100487267 (plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100487267 (plcb3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 100487267
NCBI-ProteinID: XP_002940270
Xenbase: XB-GENE-1008413
UniProt: A0A6I8R459
Position
4:complement(35339010..35419591)
AA seq 1210 aa
MAGARPGVHSLQLEPVKVPETLIKGSKFIKWDEEPSSKSLVTLRVDAMGFYLYWTCPNME
VDILDISLIRDTRIGKYAKIPKDMKMREILGFTAPEHRPEDKLFTVVHGTDIVNISFLNF
MAVQEDTAKVWTEELFKLAHNILAQNSSRNTFLQKSYTKLKLQVNQDGRIPVKNILKMFA
ADKKRVETALESCGLNFNRGDSIKPEEFTLDIFERFLNKLCLRPDIDKILLELGAKGKPY
LTLEQLMDFLNQKQRDPRLNEILFPPLKRDQVRQLIEKYEPNRQFLERDQMSMEGFSRFL
GGDENSIVPPEILDLSDDMNQPLSSYFINSSHNTYLTAGQLTGNSSVETYRQVLLTGCRC
IELDCWKGRPQDEEPFITHGFTMTTEIPFKEVIEAIAESAFKTSPFPVILSFENHVDSSK
QQAKMAEYCRNIFGDALLIDPLEKYPLQAGVQLPSPQELMGKILVKNKKRHKVAAKGPEG
SVKRRVSEQTSNTYSDSSSVCESSATGILPSESADVTLTLSNGDEKVEEKPPRYTEPRKS
IDHDAYSEEEEEEEPSDPKKSDEGTASSEVNATEEMSTLVNYVEPVKFKSFDVAKKRNKY
YEMSSFVETKALEQLTKSPMEFVEYNKKQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVAL
NFQTLDLPMQLNVGIFEYNRRSGFLLKPEFMRRTDKHFDPFTENIVDGIVANTVKIKIIS
GQFLSEKRVGIYVEVDMFGLPVDTKRKFRTKTSQGNSFNPVWDEEPFIFPKVVLPTLASL
RIAVFEEGGKFVGHRILPVSAIRPGYHYICLRNELNQPVCLPALLVYTEVNDYIPDDHQG
YANALTNPIKHINLMDQRAKQLIALMGENEQLFNKDKSDWDPKSKPQIRSPDDTPEKNKI
PIIPVPSPPAQRDDHIASVLTDIQAPSMEELKSQKSFEKLICRQYRELRQLRRKHLRKVS
SLCKEQSTWVTQLQSIRRRKPFGRSHRAVSGADQDAEQKFMDMQLDQQKRLLELREIQHE
QERKLKHSHLLQAVQKLQEVAISCHSTQLKKLKEINEKEKKELQKILDRKRHNSITEAKS
RERQKKDVELTEINRRHINESVSSIRRLEEAQKRRQEKLQAAHQETLQRIKDEEPKLQAQ
LDESCQAEFRQLPQEVRRYLQEDGWVGSGSGPPSSSHSSPPSISRSWGSESGEKDSLHSP
GDSSDEATRL
NT seq 3633 nt   +upstreamnt  +downstreamnt
atggcgggggcacggccaggggttcactctcttcagctggaaccagtcaaagtgccggag
actcttataaaagggagcaagttcatcaagtgggatgaggagcccagcagcaaatccctg
gttactctgcgtgtggatgcaatggggttttatctttactggacctgtccaaatatggag
gttgatattttggatatcagcttgataagggacacccggataggaaaatatgctaaaatt
ccaaaggatatgaaaatgagggagattctgggattcacagccccagagcaccgccctgag
gataaacttttcacagtagtacatggcaccgatattgtgaatataagctttctcaacttc
atggctgtgcaagaggatactgcaaaggtttggacagaagaactttttaaattggcacat
aatattctggcacagaactcatctcggaacacctttctgcagaaatcatacaccaaacta
aagctgcaagtgaatcaagatggacgaattccagtgaagaatatcctaaagatgtttgca
gctgataagaaaagagtggaaacggcgctggaatcttgtggcttgaactttaacagggga
gattctattaaaccggaggaatttactcttgatatttttgaacgcttcctgaacaagctg
tgcctgcgtccggatatcgataagatccttttagaacttggagccaaagggaagccgtat
ctgactctagagcaactaatggactttctaaatcagaaacaaagggacccccgactcaac
gagattctttttcctccacttaaaagagaccaagtgcggcagcttattgagaagtatgag
cccaacaggcagttcctggaaagagaccagatgtccatggaaggtttcagccgcttctta
ggtggagatgagaacagcattgttccgccagagatcctggatctaagtgatgatatgaac
cagccgctcagcagctactttattaactcttcccataacacctacctcacagctggccag
ctaactggaaactcatcagtggagacgtacaggcaagtgctattaactggctgccgctgt
attgagctagactgctggaagggacgcccccaggatgaagaaccgttcataacccatgga
ttcactatgaccactgaaattccttttaaggaagtaattgaagcaatagcagaaagtgcc
tttaaaacatcaccttttcctgtcattttgtcatttgaaaatcacgttgactcttcaaag
cagcaagcaaagatggccgagtactgcaggaacatctttggagatgcattgttaatagat
ccattggagaagtatcctctccaggctggagttcaacttcctagtccccaggaactaatg
ggtaagatcctagtgaagaataaaaaaaggcacaaagtggcagcaaaaggcccagaaggc
agcgtaaaaagaagggtcagcgaacagacctctaatacttacagtgactcatccagtgtg
tgcgagtcttctgctacaggtatcctaccttctgaatcagctgatgttacactgacactt
tccaatggggatgaaaaagtagaggagaaaccccctagatatacagagccacggaaatca
attgatcatgatgcttatagtgaggaggaagaagaagaagagccatcggatcccaagaaa
tctgatgagggtacagcaagcagtgaggtgaatgccacagaggagatgtccacacttgta
aattatgtagaacctgttaagttcaagtcatttgatgtggccaaaaaaagaaataagtat
tatgagatgtcctcatttgttgaaactaaggcattggagcagctcactaaatccccaatg
gaatttgtggaatataacaagaagcagctcagccgcatatacccaaaaggaactcgggta
gattcctcaaattacatgccccagctcttctggaatgcaggatgtcaaatggtggctttg
aactttcaaacgttggatcttccaatgcagctgaatgtgggaatttttgagtataatcga
cgcagtggtttccttctaaaaccagaatttatgcgaaggacagacaagcattttgatcct
tttactgaaaacattgttgatggaattgttgcaaatacggttaaaatcaagattatatca
gggcagtttctatctgaaaagcgagtgggcatatatgtggaggtcgatatgtttggcctg
ccagttgacactaagaggaaatttcgcacaaaaacttcccaaggaaactcatttaatcct
gtctgggacgaagagccttttatttttcctaaggttgtactccccacacttgcctctctc
cgtattgctgtctttgaagaaggtggaaagtttgtaggtcacagaatactgcctgtctct
gctatccgaccaggatatcattacatttgcctaagaaacgagctaaatcagcctgtctgt
ttgccagctctgcttgtttacactgaagtcaatgattatattcctgatgaccaccagggc
tatgccaatgccttaactaaccctatcaagcacatcaacctcatggatcaaagggcaaag
caacttatagctctgatgggagagaatgagcaactattcaacaaagacaagtctgattgg
gatccaaaatcaaagccccagataagatccccagatgataccccagagaagaataagata
ccaattattcctgtgccttccccaccagcgcaacgagatgaccacatagccagtgttctg
acagacatacaagccccctctatggaagagctcaaatcccaaaagagctttgaaaagctg
atctgccgccagtacagagaactgcgtcaactccgtcgcaagcacttgcgcaaggtgtca
tctctgtgcaaggagcagagcacttgggtgacacagctgcagagtatccgcaggaggaag
ccatttggaagaagccatagagcagtttctggtgcagatcaggatgctgagcaaaagttt
atggatatgcagctggaccaacagaagcgacttctggaactgcgagaaattcaacatgag
caggaacgtaaactaaaacacagccacttactgcaggctgttcagaagctccaggaagtg
gccatttcctgccattctactcaactcaagaagttaaaggaaatcaatgaaaaggagaag
aaagagctacagaagatcctggacagaaaacgacataatagcatcacagaggccaagtca
cgggaacgtcagaaaaaggacgtggaactgacagaaattaatagacgtcacattaatgag
tccgtaagctccatacgaaggctggaagaggcccagaaaaggcgacaagagaagctgcag
gcggctcaccaggaaacactgcaaaggataaaagatgaggagccaaagctgcaggcacag
ttagatgagtcttgccaagctgagttccgccagctgccccaggaggtccgacgttacttg
caggaggatggctgggttggcagtggttcaggtcctccctcttcttcacacagcagcccg
ccctcaataagccggagctgggggtcggagtctggcgaaaaagattctcttcattcccct
ggagactcaagtgatgaagccaccaggctctga

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (16)   

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