| D00136 |
Haloperidol (JP18/USP/INN); Haldol (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(P) CYP induction: CYP3A4 |
| D00292 |
Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) Enzyme: CYP3A4 |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00420 |
Mitotane (JAN/USP/INN); Lysodren (TN) |
(P) unclassified |
| D00426 |
Risperidone (JP18/USP/INN); Risperdal (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) unclassified |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) unclassified |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(P) Enzyme: CYP3A4 |
| D00603 |
Timolol maleate (JP18/USP); Blocadren (TN); Istalol (TN); Timoptic (TN) |
(P) CYP inhibition: CYP2D6 |
| D00636 |
Amiodarone hydrochloride (JP18/USP); Ancaron (TN); Cordarone (TN); Nexterone (TN) |
(P) Enzyme: CYP3A4 |
| D00661 |
Cevimeline hydrochloride (USAN); Cevimeline hydrochloride hydrate (JAN); Evoxac (TN); Saligren (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) unclassified |
| D00809 |
Amitriptyline hydrochloride (JP18/USP); Elavil (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00811 |
Clomipramine hydrochloride (JP18/USP); Anafranil (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00815 |
Imipramine hydrochloride (JP18/USP); Tofranil (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00831 |
Mefloquine hydrochloride (JP18/USP); Lariam (TN) |
(P) unclassified |
| D00848 |
Dextromethorphan hydrobromide (USP); Dextromethorphan hydrobromide hydrate (JP18); Benylin DM (TN) |
(P) CYP inhibition: CYP2D6 |
| D00941 |
Pamidronate disodium (USP); Pamidronate disodium hydrate (JAN); Pamidronate disodium pentahydrate; Aredia (TN) |
(P) unclassified |
| D00961 |
Bicalutamide (JP18/USP/INN); Casodex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00973 |
Cortisone acetate (JP18/USP); Cortone acetate (TN) |
(P) unclassified |
| D00977 |
Hydrocortisone sodium phosphate (JP18/USP); Hydrocortone phosphate (TN) |
(P) unclassified |
| D01164 |
Aripiprazole (JAN/USP/INN); Abilify (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) Enzyme: CYP3A4 |
| D01898 |
Haloperidol decanoate (JAN/USP); Halomonth (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D01968 |
Zoledronic acid (USAN); Zoledronic acid hydrate (JAN); Zometa (TN); Reclast (TN) |
(P) unclassified |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) unclassified |
| D02372 |
Perospirone hydrochloride hydrate (JAN); Lullan (TN) |
(P) unclassified |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) unclassified |
| D02574 |
Atomoxetine hydrochloride (JAN/USP); Tomoxetine hydrochloride; Strattera (TN) |
(P) CYP inhibition: CYP2D6 |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) unclassified |
| D02732 |
Pranlukast hydrate (JP18); Onon (TN) |
(P) Enzyme: CYP3A4 |
| D02968 |
Aprepitant (JAN/USP/INN); Aponvie (TN); Emend (TN); Cinvanti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) unclassified |
| D03658 |
Dasatinib (JAN/INN) |
(P) Enzyme: CYP3A4 |
| D03669 |
Deferasirox (JAN/USAN/INN); Exjade (TN); Jadenu (TN) |
(P) CYP induction: CYP3A4 |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Enzyme: CYP3A4 |
| D04148 |
Fenfluramine hydrochloride (JAN/USAN); Fintepla (TN); Pondimin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D04340 |
Dextromethorphan hydrobromide and potassium cresolsulfonate; Medicon (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D04666 |
Lanreotide acetate (JAN/USAN); Somatuline (TN) |
(P) unclassified |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D06413 |
Nilotinib hydrochloride hydrate (JAN); Nilotinib monohydrochloride monohydrate; Tasigna (TN) |
(P) Enzyme: CYP3A4 |
| D06414 |
Dasatinib (USAN); Dasatinib hydrate (JAN); Sprycel (TN) |
(P) Enzyme: CYP3A4 |
| D06597 |
Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN); Proemend (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D07505 |
Latanoprost and timolol maleate; Xalacom (TN) |
(P) unclassified |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) unclassified |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) CYP induction: CYP3A4 |
| D08493 |
Dorzolamide hydrochloride and timolol maleate (JP18); Cosopt (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D08575 |
Tetrabenazine (JAN/INN); Nitoman (TN); Xenazine (TN) |
(P) CYP inhibition: CYP2D6 |
| D08923 |
Fesoterodine fumarate (JAN/USAN); Toviaz (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(P) Enzyme: CYP3A4 |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) Enzyme: CYP3A4 |
| D09799 |
Carotegrast methyl (JAN); Carogra (TN) |
(P) CYP inhibition: CYP3A4 |
| D09815 |
Travoprost and timolol maleate; Duotrav (TN) |
(P) unclassified |
| D09894 |
Eliglustat tartrate (JAN/USAN); Eliglustat hemitartrate; Cerdelga (TN) |
(CI,P) CYP inhibition: CYP2D6 |
| D09996 |
Vemurafenib (JAN/USAN/INN); Zelboraf (TN) |
(P) CYP induction: CYP3A4 |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) CYP induction: CYP3A4 |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10161 |
Sarilumab (USAN); Sarilumab (genetical receombination) (JAN); Kevzara (TN) |
(P) unclassified |
| D10185 |
Vortioxetine hydrobromide (JAN/USAN); Brintellix (TN); Trintellix (TN) |
(P) CYP inhibition: CYP2D6 |
| D10218 |
Enzalutamide (JAN/USAN); Xtandi (TN) |
(P) unclassified |
| D10298 |
Brimonidine tartrate and timolol maleate; Combigan (TN); Aibeta (TN) |
(P) unclassified |
| D10309 |
Brexpiprazole (JAN/USAN/INN); Rexulti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10466 |
Vonoprazan fumarate (JAN/USAN); Takecab (TN); Voquezna (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10512 |
Brinzolamide and timolol maleate; Azorga (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10516 |
Aripiprazole hydrate (JAN); Aripiprazole monohydrate; Abilify maintena (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) unclassified |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) unclassified |
| D10566 |
Pasireotide pamoate (JAN); Signifor lar (TN) |
(P) unclassified |
| D10569 |
Tafluprost and timolol maleate; Tapcom (TN) |
(P) unclassified |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(P) unclassified |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) unclassified |
| D10774 |
Vonoprazan, amoxicillin and metronidazole; Vonopion (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10775 |
Vonoprazan, amoxicillin and clarithromycin; Vonosap (TN); Voquenza (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 CYP3A4 |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) unclassified |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) Enzyme: CYP3A4 |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D10999 |
Valbenazine tosylate (USAN); Valbenazine tosilate (JAN); Valbenazine ditosylate; Ingrezza (TN); Dysval (TN) |
(P) Enzyme: CYP3A4 |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) unclassified |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) unclassified |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) unclassified |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) CYP inhibition: CYP3A4 |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) Enzyme: CYP3A4 |
| D11804 |
Aspirin and vonoprazan; Cabpirin (TN) |
(P) unclassified |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) unclassified |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) unclassified |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) unclassified |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(P) unclassified |
