| D00125 |
Etoposide (JP18/USP/INN); Vepesid (TN) |
(P) unclassified |
| D00136 |
Haloperidol (JP18/USP/INN); Haldol (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00168 |
Cytarabine (JP18/USP/INN); ARA-C; Depocyt (TN) |
(P) unclassified |
| D00208 |
Mitomycin (USP/INN); Mitomycin C (JP18); MMC; Jelmyto (TN); Mitomycin (TN); Muamycin (TN) |
(P) unclassified |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(CI,P) CYP induction: CYP3A4 |
| D00214 |
Dactinomycin (USP); Actinomycin D (JP18); Cosmegen (TN) |
(P) unclassified |
| D00252 |
Carbamazepine (JP18/USP/INN); Equetro (TN); Tegretol (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00275 |
Cisplatin (JP18/USP/INN); Platinol (TN) |
(P) unclassified |
| D00287 |
Cyclophosphamide (USP); Cyclophosphamide hydrate (JP18); Cytoxan (TN); Neosar (TN) |
(P) Enzyme: CYP3A4 |
| D00288 |
Dacarbazine (JAN/USP/INN); DTIC-Dome (TN) |
(P) unclassified |
| D00292 |
Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) Enzyme: CYP3A4 |
| D00323 |
Flucytosine (JP18/USP/INN); Ancobon (TN) |
(P) unclassified |
| D00341 |
Hydroxyurea (USP); Hydroxycarbamide (JAN/INN); Droxia (TN); Hydrea (TN); Siklos (TN) |
(P) unclassified |
| D00343 |
Ifosfamide (JAN/USP/INN); Ifex (TN) |
(P) Enzyme: CYP3A4 |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00420 |
Mitotane (JAN/USP/INN); Lysodren (TN) |
(P) unclassified |
| D00426 |
Risperidone (JP18/USP/INN); Risperdal (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00491 |
Paclitaxel (JAN/USP/INN); Abraxane (TN); Taxol (TN) |
(P) Enzyme: CYP3A4 |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) unclassified |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) unclassified |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(P) Enzyme: CYP3A4 |
| D00584 |
Fluorouracil (JP18/USP/INN); 5-FU (TN); Adrucil (TN); Carac (TN); Fluoroplex (TN) |
(P) unclassified |
| D00603 |
Timolol maleate (JP18/USP); Blocadren (TN); Istalol (TN); Timoptic (TN) |
(P) CYP inhibition: CYP2D6 |
| D00636 |
Amiodarone hydrochloride (JP18/USP); Ancaron (TN); Cordarone (TN); Nexterone (TN) |
(P) Enzyme: CYP3A4 |
| D00661 |
Cevimeline hydrochloride (USAN); Cevimeline hydrochloride hydrate (JAN); Evoxac (TN); Saligren (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) unclassified |
| D00809 |
Amitriptyline hydrochloride (JP18/USP); Elavil (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D00831 |
Mefloquine hydrochloride (JP18/USP); Lariam (TN) |
(P) unclassified |
| D00848 |
Dextromethorphan hydrobromide (USP); Dextromethorphan hydrobromide hydrate (JP18); Benylin DM (TN) |
(P) CYP inhibition: CYP2D6 |
| D00961 |
Bicalutamide (JP18/USP/INN); Casodex (TN) |
(P) CYP inhibition: CYP3A4 |
| D01059 |
Nimustine hydrochloride (JAN); Nidran (TN) |
(P) unclassified |
| D01061 |
Irinotecan hydrochloride (USP); Irinotecan hydrochloride hydrate (JP18); Irinotecan hydrochloride trihydrate; CPT 11; CPT-11; Campto (TN); Camptosar (TN); Onivyde (TN) |
(P) unclassified |
| D01068 |
Vinblastine sulfate (JP18/USP); Exal (TN); Velban (TN) |
(P) Enzyme: CYP3A4 |
| D01155 |
Gemcitabine hydrochloride (JAN/USP); Gemzar (TN) |
(P) unclassified |
| D01164 |
Aripiprazole (JAN/USP/INN); Abilify (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D01211 |
Leucovorin calcium (USP); Calcium folinate (JP18); Uzel (TN); Wellcovorin (TN) |
(P) unclassified |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) Enzyme: CYP3A4 |
| D01264 |
Daunorubicin hydrochloride (JP18/USP); Cerubidine (TN) |
(P) unclassified |
| D01275 |
Doxorubicin hydrochloride (JP18/USP); Adriacin (TN); Adriamycin (TN); Doxil (TN); Rubex (TN) |
(P) unclassified |
| D01280 |
Warfarin potassium (JP18); Athrombin-K (TN) |
(P) unclassified |
| D01309 |
Doxifluridine (JP18/INN); Furtulon (TN) |
(P) unclassified |
| D01363 |
Carboplatin (JP18/USP/INN); Paraplatin (TN) |
(P) unclassified |
| D01404 |
Sobuzoxane (JAN); Perazolin (TN) |
(P) unclassified |
| D01416 |
Nedaplatin (JAN/INN); Aqupla (TN) |
(P) unclassified |
| D01633 |
Enocitabine (JAN/INN); Sunrabin (TN) |
(P) unclassified |
| D01747 |
Idarubicin hydrochloride (JP18/USP); Idamycin (TN) |
(P) unclassified |
| D01760 |
Ranimustine (JAN/INN); Cymerin (TN) |
(P) unclassified |
| D01769 |
Vindesine sulfate (JAN/USAN); Fildesin (TN) |
(P) unclassified |
| D01790 |
Oxaliplatin (JAN/USP/INN); Eloxatin (TN) |
(P) unclassified |
| D01898 |
Haloperidol decanoate (JAN/USP); Halomonth (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D01907 |
Fludarabine phosphate (JAN/USP); Fludara (TN) |
(P) unclassified |
| D01911 |
Aclarubicin hydrochloride (JP18); Aclacinon (TN) |
(P) unclassified |
| D01935 |
Vinorelbine tartrate (USP); Vinorelbine ditartrate (JAN); KW 2307; Navelbine (TN) |
(P) Enzyme: CYP3A4 |
| D02063 |
Peplomycin sulfate (JP18/USAN); Pepleo (TN) |
(P) unclassified |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) unclassified |
| D02126 |
Primaquine phosphate (JAN/USP); Primaquine (TN) |
(P) unclassified |
| D02131 |
Tegafur and uracil; Uftoral (TN) |
(P) unclassified |
| D02165 |
Docetaxel (USP); Docetaxel hydrate (JP18); Docetaxel trihydrate; Taxotere (TN) |
(P) Enzyme: CYP3A4 |
| D02166 |
Mitoxantrone hydrochloride (JAN/USP); Novantron (TN) |
(P) unclassified |
| D02168 |
Topotecan hydrochloride (USAN); Nogitecan hydrochloride (JAN); Hycamtin (TN); Potactasol (TN) |
(P) unclassified |
| D02177 |
Bleomycin sulfate (JP18/USP); Blenoxane (TN) |
(P) unclassified |
| D02197 |
Vincristine sulfate (JP18/USP); VCR; Marqibo (TN); Oncovin (TN); Vincasar (TN); Vincrex (TN) |
(P) unclassified |
| D02214 |
Epirubicin hydrochloride (JP18/USP); EPI; Ellence (TN) |
(P) unclassified |
| D02372 |
Perospirone hydrochloride hydrate (JAN); Lullan (TN) |
(P) unclassified |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) unclassified |
| D02574 |
Atomoxetine hydrochloride (JAN/USP); Tomoxetine hydrochloride; Strattera (TN) |
(P) CYP inhibition: CYP2D6 |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) unclassified |
| D02732 |
Pranlukast hydrate (JP18); Onon (TN) |
(P) Enzyme: CYP3A4 |
| D02968 |
Aprepitant (JAN/USP/INN); Aponvie (TN); Emend (TN); Cinvanti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D03046 |
Cytarabine ocfosfate hydrate (JAN); Cytarabine ocfosphate hydrate; Fosteabine sodium monohydrate; Starasid (TN) |
(P) unclassified |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) unclassified |
| D03229 |
Bleomycin hydrochloride (JP18); BLM; Bleo (TN) |
(P) unclassified |
| D03230 |
Insulin human (USP/INN); Insulin human (genetical recombination) (JP18); Insulin human (biosynthesis) (JAN); Insulin human (synthesis) (JAN); Humulin (TN) |
(P) unclassified |
| D03250 |
Insulin glargine (USAN/INN); Insulin glargine (genetical recombination) (JP18); Insulin glargine (genetical recombination) [Insulin glargin biosimilar 1] (JAN); Insulin glargine (genetical recombination) [Insulin glargin biosimilar 2] (JAN); Lantus (TN) |
(P) unclassified |
| D03658 |
Dasatinib (JAN/INN) |
(P) Enzyme: CYP3A4 |
| D03669 |
Deferasirox (JAN/USAN/INN); Exjade (TN); Jadenu (TN) |
(P) CYP induction: CYP3A4 |
| D03846 |
Dimethyl fumarate (JAN/USAN); Tecfidera (TN) |
(P) unclassified |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Enzyme: CYP3A4 |
| D04148 |
Fenfluramine hydrochloride (JAN/USAN); Fintepla (TN); Pondimin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D04187 |
Fingolimod hydrochloride (JAN/USAN); Gilenya (TN) |
(P) unclassified |
| D04340 |
Dextromethorphan hydrobromide and potassium cresolsulfonate; Medicon (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D04475 |
Insulin aspart (USP/INN); Insulin aspart (genetical recombination) (JP18); Insulin aspart (genetical recombination) [Insulin aspart biosimilar 1] (JAN); Insulin X 14; NovoRapid (TN); Novolog (TN) |
(P) unclassified |
| D04477 |
Insulin lispro (USP/INN); Insulin lispro (genetical recombination) (JAN); Insulin lispro (genetical recombination) [Insulin lispro Biosimilar 1] (JAN); Insulin lispro-aabc; Humalog (TN); Lyumjev (TN) |
(P) unclassified |
| D04539 |
Insulin detemir (USAN/INN); Insulin detemir (genetical recombination) (JAN); Levemir (TN) |
(P) unclassified |
| D04540 |
Insulin glulisine (USAN/INN); Insulin glulisine (genetical recombination) (JAN); Apidra (TN) |
(P) unclassified |
| D04547 |
Insulin, isophane (USP); Isophane insulin human (genetical recombination) injectable aqueous suspension (JP18); Isophane insulin (aqueous suspension) (JAN); Humalog PEN (TN) |
(P) unclassified |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D04666 |
Lanreotide acetate (JAN/USAN); Somatuline (TN) |
(P) unclassified |
| D04768 |
Lonafarnib (JAN/USAN/INN); Zokinvy (TN) |
(P) unclassified |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D05932 |
Streptozocin (JAN/USAN/INN); Streptozotocin; Zanosar (TN) |
(P) unclassified |
| D06399 |
Tegafur, gimeracil and oteracil potassium; Ts-1 (TN); Teysuno (TN) |
(P) unclassified |
| D06413 |
Nilotinib hydrochloride hydrate (JAN); Nilotinib monohydrochloride monohydrate; Tasigna (TN) |
(P) Enzyme: CYP3A4 |
| D06414 |
Dasatinib (USAN); Dasatinib hydrate (JAN); Sprycel (TN) |
(P) Enzyme: CYP3A4 |
| D06503 |
Pemetrexed sodium hydrate (JAN); Pemetrexed disodium heptahydrate; Alimta (TN) |
(P) unclassified |
| D06597 |
Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN); Proemend (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D07085 |
Bendamustine hydrochloride (JAN/USAN); Treanda (TN); Ribomustin (TN) |
(P) unclassified |
| D07100 |
Amrubicin hydrochloride (JAN/USAN); Calsed (TN) |
(P) unclassified |
| D07505 |
Latanoprost and timolol maleate; Xalacom (TN) |
(P) unclassified |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) unclassified |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) CYP induction: CYP3A4 |
| D07866 |
Docetaxel (JAN/INN); Docetaxel (TN); Taxotere (TN) |
(P) Enzyme: CYP3A4 |
| D08080 |
Insulin injection, biphasic isophane (BAN); Biphasic isophane insuline human (genetical recombination) injectable aqueous suspension (JP18); Insulin Humacart (TN) |
(P) unclassified |
| D08386 |
Pirarubicin hydrochloride; Pinorubin (TN); Therarubicin (TN) |
(P) unclassified |
| D08493 |
Dorzolamide hydrochloride and timolol maleate (JP18); Cosopt (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D08575 |
Tetrabenazine (JAN/INN); Nitoman (TN); Xenazine (TN) |
(P) CYP inhibition: CYP2D6 |
| D08914 |
Eribulin mesylate (USAN); Eribulin mesilate (JAN); Halaven (TN) |
(P) Enzyme: CYP3A4 |
| D08923 |
Fesoterodine fumarate (JAN/USAN); Toviaz (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D09197 |
Valsartan and hydrochlorothiazide (JP18); Co-dio (TN) |
(P) unclassified |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(P) Enzyme: CYP3A4 |
| D09727 |
Insulin degludec (USAN/INN); Insulin degludec (genetical recombination) (JAN); Tresiba (TN) |
(P) unclassified |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) Enzyme: CYP3A4 |
| D09799 |
Carotegrast methyl (JAN); Carogra (TN) |
(P) CYP inhibition: CYP3A4 |
| D09815 |
Travoprost and timolol maleate; Duotrav (TN) |
(P) unclassified |
| D09894 |
Eliglustat tartrate (JAN/USAN); Eliglustat hemitartrate; Cerdelga (TN) |
(CI,P) CYP inhibition: CYP2D6 |
| D09996 |
Vemurafenib (JAN/USAN/INN); Zelboraf (TN) |
(P) CYP induction: CYP3A4 |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) CYP induction: CYP3A4 |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10161 |
Sarilumab (USAN); Sarilumab (genetical receombination) (JAN); Kevzara (TN) |
(P) unclassified |
| D10185 |
Vortioxetine hydrobromide (JAN/USAN); Brintellix (TN); Trintellix (TN) |
(P) CYP inhibition: CYP2D6 |
| D10218 |
Enzalutamide (JAN/USAN); Xtandi (TN) |
(P) unclassified |
| D10298 |
Brimonidine tartrate and timolol maleate; Combigan (TN); Aibeta (TN) |
(P) unclassified |
| D10309 |
Brexpiprazole (JAN/USAN/INN); Rexulti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10466 |
Vonoprazan fumarate (JAN/USAN); Takecab (TN); Voquezna (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10512 |
Brinzolamide and timolol maleate; Azorga (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10516 |
Aripiprazole hydrate (JAN); Aripiprazole monohydrate; Abilify maintena (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10526 |
Trifluridine and tipiracil hydrochloride; Lonsurf (TN) |
(P) unclassified |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) unclassified |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) unclassified |
| D10566 |
Pasireotide pamoate (JAN); Signifor lar (TN) |
(P) unclassified |
| D10569 |
Tafluprost and timolol maleate; Tapcom (TN) |
(P) unclassified |
| D10570 |
Insulin degludec (genetical recombination) and insulin aspart (genetical recombination); Ryzodeg (TN) |
(P) unclassified |
| D10596 |
Pemetrexed sodium hemipentahydrate (JAN); Pemetrexed disodium hemipentahydrate; Pemetrexed accord (TN) |
(P) unclassified |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(P) unclassified |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) unclassified |
| D10774 |
Vonoprazan, amoxicillin and metronidazole; Vonopion (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 |
| D10775 |
Vonoprazan, amoxicillin and clarithromycin; Vonosap (TN); Voquenza (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP2D6 CYP3A4 |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) unclassified |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) Enzyme: CYP3A4 |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D10999 |
Valbenazine tosylate (USAN); Valbenazine tosilate (JAN); Valbenazine ditosylate; Ingrezza (TN); Dysval (TN) |
(P) Enzyme: CYP3A4 |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) unclassified |
| D11034 |
Insulin glargine and lixisenatide; Insulin glargine (genetical recombination) and lixisenatide; Soliqua (TN) |
(P) unclassified |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11072 |
Siponimod fumarate (USAN); Siponimod fumaric acid (JAN); Mayzent (TN) |
(P) unclassified |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) unclassified |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11390 |
Daunorubicin and cytarabine; Vyxeos (TN) |
(P) unclassified |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) unclassified |
| D11567 |
Insulin degludec and liraglutide; Xultophy (TN) |
(P) unclassified |
| D11661 |
Bendamustine hydrochloride hydrate (JAN); Bendamustine hydrochloride monohydrate; Treakisym (TN) |
(P) unclassified |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) CYP inhibition: CYP3A4 |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) Enzyme: CYP3A4 |
| D11804 |
Aspirin and vonoprazan; Cabpirin (TN) |
(P) unclassified |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) unclassified |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) unclassified |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) unclassified |
| D12353 |
Ensitrelvir fumarate (USAN); Ensitrelvir fumaric acid (JAN); Xocova (TN) |
(P) unclassified |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(P) unclassified |
