+D GENES KO
#
KEGG Orthology (KO) - Anaplasma centrale
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:acn00010]
D ACIS_00374 glpX; fructose 1,6-bisphosphatase 2 K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D ACIS_00202 fbaB; fructose-bisphosphate aldolase, class 1 K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D ACIS_00750 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D ACIS_00119 gap; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACIS_00081 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D ACIS_00539 gpmI; phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D ACIS_00715 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D ACIS_01086 ppdK; pyruvate phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D ACIS_01167 pdhA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D ACIS_01197 pdhB; pyruvate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D ACIS_00204 pdhC; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00020 Citrate cycle (TCA cycle) [PATH:acn00020]
D ACIS_00209 gltA; citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D ACIS_00321 acnA; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D ACIS_00241 icd; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D ACIS_00895 sucA; alpha-ketoglutarate decarboxylase K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D ACIS_00275 putative dihydrolipoamide acetyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01062 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D ACIS_01060 sucC; succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D ACIS_01108 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D ACIS_01107 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D ACIS_01005 sdhC; succinate dehydrogenase cytochrome B-556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D ACIS_01004 sdhD; putative succinate dehydrogenase SdhD K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D ACIS_00402 fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D ACIS_00745 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D ACIS_01167 pdhA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D ACIS_01197 pdhB; pyruvate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D ACIS_00204 pdhC; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:acn00030]
D ACIS_00187 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D ACIS_00488 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D ACIS_00641 putative transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D ACIS_00742 rpiB; ribose 5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D ACIS_00323 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D ACIS_00202 fbaB; fructose-bisphosphate aldolase, class 1 K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D ACIS_00374 glpX; fructose 1,6-bisphosphatase 2 K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
C 00040 Pentose and glucuronate interconversions
D ACIS_00187 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:acn00051]
D ACIS_00374 glpX; fructose 1,6-bisphosphatase 2 K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D ACIS_00202 fbaB; fructose-bisphosphate aldolase, class 1 K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D ACIS_00750 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D ACIS_00742 rpiB; ribose 5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
C 00052 Galactose metabolism
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:acn00520]
D ACIS_00337 glmS; D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D ACIS_00398 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D ACIS_00037 glmU; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D ACIS_01131 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D ACIS_00619 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
C 00620 Pyruvate metabolism [PATH:acn00620]
D ACIS_01167 pdhA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D ACIS_01197 pdhB; pyruvate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D ACIS_00204 pdhC; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_00022 maeB; malic enzyme K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D ACIS_00745 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D ACIS_00402 fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D ACIS_01086 ppdK; pyruvate phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:acn00630]
D ACIS_00745 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D ACIS_00209 gltA; citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D ACIS_00321 acnA; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D ACIS_00511 pccA; propionyl-CoA carboxylase alpha chain K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D ACIS_00562 pccB; propionyl-CoA carboxylase, beta subunit K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
D ACIS_01083 putative phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D ACIS_00194 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01066 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01111 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:acn00640]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_00872 mcd; malonyl-CoA decarboxylase K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
D ACIS_00511 pccA; propionyl-CoA carboxylase alpha chain K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D ACIS_00562 pccB; propionyl-CoA carboxylase, beta subunit K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
D ACIS_01060 sucC; succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D ACIS_01062 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D ACIS_00321 acnA; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
C 00650 Butanoate metabolism
D ACIS_01108 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D ACIS_01107 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D ACIS_01005 sdhC; succinate dehydrogenase cytochrome B-556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D ACIS_01004 sdhD; putative succinate dehydrogenase SdhD K00242 sdhD; succinate dehydrogenase membrane anchor subunit
C 00660 C5-Branched dibasic acid metabolism
D ACIS_01060 sucC; succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D ACIS_01062 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00562 Inositol phosphate metabolism [PATH:acn00562]
D ACIS_00829 inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D ACIS_00750 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:acn00190]
D ACIS_00846 nuoA; NADH dehydrogenase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D ACIS_00847 nuoB; NADH dehydrogenase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D ACIS_00848 nuoC; NADH dehydrogenase subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D ACIS_00692 nuoD; NADH dehydrogenase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D ACIS_00691 nuoE; NADH dehydrogenase subunit E K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D ACIS_00577 nuoF; NADH dehydrogenase subunit F K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D ACIS_00664 nuoG; NADH dehydrogenase subunit G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D ACIS_00665 nuoH; NADH dehydrogenase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D ACIS_00615 nuoI; NADH dehydrogenase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D ACIS_00578 nuoJ; NADH dehydrogenase subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D ACIS_00579 nuoK; NADH dehydrogenase subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D ACIS_00580 nuoL; NADH dehydrogenase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D ACIS_00582 nuoM; NADH dehydrogenase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D ACIS_00583 nuoN; NADH dehydrogenase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D ACIS_01108 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D ACIS_01107 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D ACIS_01005 sdhC; succinate dehydrogenase cytochrome B-556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D ACIS_01004 sdhD; putative succinate dehydrogenase SdhD K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D ACIS_00553 petA; ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D ACIS_00554 petB; cytochrome B K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D ACIS_00555 petC; ubiquinol-cytochrome c reductase, cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D ACIS_00343 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D ACIS_00104 coxC; cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D ACIS_00344 coxA; cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D ACIS_00345 cytochrome c oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D ACIS_00290 ctaG; cytochrome C oxidase assembly protein K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D ACIS_01134 coxW; cytochrome C oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D ACIS_01090 cycM; cytochrome c K08738 CYC; cytochrome c
D ACIS_00219 atpA; F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D ACIS_00639 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D ACIS_00694 atpG; F0F1 ATP synthase subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D ACIS_00217 atpH; ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D ACIS_00640 atpC; F0F1-type ATP synthase, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D ACIS_00258 atpA; ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D ACIS_00255 hypothetical protein K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D ACIS_00254 hypothetical protein K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D ACIS_00256 atpE; ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D ACIS_00330 ppa; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:acn00710]
D ACIS_00081 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D ACIS_00119 gap; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACIS_00202 fbaB; fructose-bisphosphate aldolase, class 1 K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D ACIS_00374 glpX; fructose 1,6-bisphosphatase 2 K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D ACIS_00488 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D ACIS_00742 rpiB; ribose 5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D ACIS_00750 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D ACIS_00187 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D ACIS_00641 putative transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D ACIS_01086 ppdK; pyruvate phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D ACIS_00022 maeB; malic enzyme K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D ACIS_00745 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:acn00720]
D ACIS_01086 ppdK; pyruvate phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D ACIS_00745 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D ACIS_00402 fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D ACIS_01108 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D ACIS_01107 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D ACIS_01005 sdhC; succinate dehydrogenase cytochrome B-556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D ACIS_01004 sdhD; putative succinate dehydrogenase SdhD K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D ACIS_01062 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D ACIS_01060 sucC; succinyl-CoA synthetase beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D ACIS_00241 icd; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D ACIS_00321 acnA; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D ACIS_01098 folD; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
C 00680 Methane metabolism [PATH:acn00680]
D ACIS_01111 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D ACIS_00715 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D ACIS_00745 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D ACIS_00202 fbaB; fructose-bisphosphate aldolase, class 1 K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D ACIS_00374 glpX; fructose 1,6-bisphosphatase 2 K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D ACIS_00539 gpmI; phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
C 00910 Nitrogen metabolism [PATH:acn00910]
D ACIS_00825 gdh; NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D ACIS_00194 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01066 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:acn00061]
D ACIS_00958 acpP; acyl carrier protein AcpP K02078 acpP; acyl carrier protein
D ACIS_01160 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D ACIS_00474 fabH; 3-oxoacyl-[acyl carrier protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D ACIS_00959 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D ACIS_00728 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D ACIS_00266 fabZ; (3R)-hydroxymyristoyl-ACP dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D ACIS_00870 fabI; enoyl-[acyl-carrier-protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D ACIS_01056 2-nitropropane dioxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis [PATH:acn00074]
D ACIS_00799 acpS; holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D ACIS_00958 acpP; acyl carrier protein AcpP K02078 acpP; acyl carrier protein
D ACIS_01160 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:acn00561]
D ACIS_00473 plsX; glycerol-3-phosphate acyltransferase/fatty acid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D ACIS_00106 hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D ACIS_00166 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 00564 Glycerophospholipid metabolism [PATH:acn00564]
D ACIS_00355 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D ACIS_00106 hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D ACIS_00166 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D ACIS_01142 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D ACIS_00840 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D ACIS_00839 psd; phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D ACIS_00994 pgpA; phosphatidylglycerophosphatase A K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
D ACIS_00264 pgsA; CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
D ACIS_00259 putative glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:acn00230]
D ACIS_00323 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D ACIS_00073 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D ACIS_00340 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D ACIS_00384 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D ACIS_00378 purQ; phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D ACIS_00367 purL; phosphoribosylformylglycinamidine synthase K23270 purSL; phosphoribosylformylglycinamidine synthase subunit PurSL [EC:6.3.5.3]
D ACIS_00357 phosphoribosylaminoimidazole synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D ACIS_00318 purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D ACIS_00003 purE; phosphoribosylaminoimidazole carboxylase catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D ACIS_01137 purC; phosphoribosoylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D ACIS_00917 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D ACIS_00265 purH; bifunctional phosphoribosylaminoimidazole carboxamide formyltransferase-IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D ACIS_00849 surE; stationary-phase survival protein K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D ACIS_01164 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D ACIS_00236 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D ACIS_00208 guaA; bifunctional GMP synthase/glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D ACIS_01101 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D ACIS_00482 nrdA; ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D ACIS_00820 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D ACIS_00485 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D ACIS_00450 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00240 Pyrimidine metabolism [PATH:acn00240]
D ACIS_00404 carB; carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D ACIS_00537 carA; carbamoyl phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D ACIS_00644 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D ACIS_00399 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D ACIS_01019 pyrD; dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D ACIS_01185 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D ACIS_00851 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D ACIS_01145 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D ACIS_00236 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D ACIS_00546 maf; Maf-like protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D ACIS_00016 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D ACIS_00425 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D ACIS_00849 surE; stationary-phase survival protein K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D ACIS_01129 dcd; deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D ACIS_00482 nrdA; ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D ACIS_00820 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D ACIS_01159 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D ACIS_00534 dut; deoxyuridine 5'triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D ACIS_01106 thyX; FAD-dependent thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:acn00250]
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D ACIS_00485 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D ACIS_00917 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D ACIS_00644 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D ACIS_00825 gdh; NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D ACIS_00730 putA; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D ACIS_00194 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01066 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_00404 carB; carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D ACIS_00537 carA; carbamoyl phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D ACIS_00378 purQ; phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D ACIS_00337 glmS; D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D ACIS_00073 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:acn00260]
D ACIS_00346 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D ACIS_00124 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D ACIS_01111 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D ACIS_00539 gpmI; phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D ACIS_00197 hemA; 5-aminolevulinate synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_00840 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
C 00270 Cysteine and methionine metabolism [PATH:acn00270]
D ACIS_01011 metC; cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D ACIS_00113 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D ACIS_00346 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D ACIS_00124 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D ACIS_00210 gshA; glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D ACIS_01080 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D ACIS_00745 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00280 Valine, leucine and isoleucine degradation [PATH:acn00280]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_00511 pccA; propionyl-CoA carboxylase alpha chain K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D ACIS_00562 pccB; propionyl-CoA carboxylase, beta subunit K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:acn00290]
D ACIS_00096 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
C 00300 Lysine biosynthesis [PATH:acn00300]
D ACIS_00346 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D ACIS_00124 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D ACIS_00892 dapA; dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D ACIS_00468 dapB; dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D ACIS_00078 dapD; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D ACIS_00974 argD; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D ACIS_01192 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D ACIS_00084 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D ACIS_01012 murE; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D ACIS_00533 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:acn00310]
D ACIS_00275 putative dihydrolipoamide acetyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00220 Arginine biosynthesis [PATH:acn00220]
D ACIS_00181 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D ACIS_00378 purQ; phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D ACIS_00194 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01066 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_00404 carB; carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D ACIS_00537 carA; carbamoyl phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D ACIS_00825 gdh; NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D ACIS_00566 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D ACIS_00974 argD; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:acn00330]
D ACIS_00730 putA; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism
C 00350 Tyrosine metabolism
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00360 Phenylalanine metabolism
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00380 Tryptophan metabolism
D ACIS_00275 putative dihydrolipoamide acetyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:acn00400]
D ACIS_01006 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:acn00410]
D ACIS_00273 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D ACIS_00872 mcd; malonyl-CoA decarboxylase K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
C 00430 Taurine and hypotaurine metabolism
D ACIS_00825 gdh; NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
C 00440 Phosphonate and phosphinate metabolism
D ACIS_01067 putative hydrolase K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:acn00450]
D ACIS_01011 metC; cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D ACIS_00794 trxB; thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D ACIS_00697 trxB; thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D ACIS_00347 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D ACIS_01111 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:acn00470]
D ACIS_01079 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D ACIS_00378 purQ; phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D ACIS_01050 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D ACIS_00084 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
C 00480 Glutathione metabolism [PATH:acn00480]
D ACIS_00210 gshA; glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D ACIS_01080 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D ACIS_00385 pepA; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D ACIS_00910 gst; glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D ACIS_00241 icd; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
D ACIS_00037 glmU; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
C 00550 Peptidoglycan biosynthesis [PATH:acn00550]
D ACIS_01131 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D ACIS_00619 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D ACIS_00011 murC; UDP-N-acetylmuramate-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D ACIS_01050 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D ACIS_01012 murE; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D ACIS_01079 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D ACIS_00533 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D ACIS_01143 uppS; undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D ACIS_00193 mraY; phospho-n-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D ACIS_00831 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D ACIS_00201 putative cell division protein FtsI/penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D ACIS_00879 pbpA; penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D ACIS_00272 dacA; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:acn00730]
D ACIS_00860 thiC; thiamine biosynthesis protein K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D ACIS_01001 thiD; phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D ACIS_00650 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00651 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00479 putative oxidoreductase K03153 thiO; glycine oxidase [EC:1.4.3.19]
D ACIS_00056 thiG; thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10]
D ACIS_00985 thiE; thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D ACIS_00756 thiL; thiamin-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D ACIS_00450 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:acn00740]
D ACIS_00089 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D ACIS_00015 ribD; riboflavin biosynthesis protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D ACIS_00221 ribA; 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D ACIS_00842 ribH; riboflavin synthase subunit beta K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D ACIS_01151 ribE; riboflavin synthase subunit alpha K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D ACIS_00281 ribF; riboflavin biosynthesis protein K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D ACIS_00660 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxyl-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:acn00750]
D ACIS_01013 pdhX; pyridoxamine 5-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]
D ACIS_00866 pdxJ; pyridoxal phosphate biosynthetic protein K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]
C 00760 Nicotinate and nicotinamide metabolism [PATH:acn00760]
D ACIS_00098 nadA; quinolinate synthetase K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D ACIS_00107 nadC; nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D ACIS_00849 surE; stationary-phase survival protein K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D ACIS_00867 putative adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D ACIS_00881 nadE; NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D ACIS_00129 cinA; competence/damage inducible protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D ACIS_01163 ppnK; inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:acn00770]
D ACIS_00096 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D ACIS_01133 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D ACIS_00273 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D ACIS_01021 panK; pantothenate kinase K03525 coaX; type III pantothenate kinase [EC:2.7.1.33]
D ACIS_00401 dfp; DNA/pantothenate metabolism flavoprotein K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
D ACIS_00795 coaD; phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D ACIS_00861 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D ACIS_00799 acpS; holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
C 00780 Biotin metabolism [PATH:acn00780]
D ACIS_00099 putative methylase K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197]
D ACIS_00959 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D ACIS_00728 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D ACIS_00266 fabZ; (3R)-hydroxymyristoyl-ACP dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D ACIS_00870 fabI; enoyl-[acyl-carrier-protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D ACIS_01024 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D ACIS_00753 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D ACIS_00244 bioD; dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D ACIS_00369 biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6]
D ACIS_00911 birA; biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:acn00785]
D ACIS_00397 lipB; lipoyltransferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D ACIS_00515 lipA; lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01167 pdhA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D ACIS_01197 pdhB; pyruvate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D ACIS_00204 pdhC; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D ACIS_00895 sucA; alpha-ketoglutarate decarboxylase K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D ACIS_00275 putative dihydrolipoamide acetyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
C 00790 Folate biosynthesis [PATH:acn00790]
D ACIS_00695 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D ACIS_00746 folB; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D ACIS_00365 putative pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D ACIS_00406 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D ACIS_00621 folC; folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D ACIS_00089 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
C 00670 One carbon pool by folate [PATH:acn00670]
D ACIS_01098 folD; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D ACIS_01111 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D ACIS_00384 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D ACIS_00265 purH; bifunctional phosphoribosylaminoimidazole carboxamide formyltransferase-IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D ACIS_00988 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D ACIS_01106 thyX; FAD-dependent thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D ACIS_00710 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:acn00860]
D ACIS_00197 hemA; 5-aminolevulinate synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D ACIS_00054 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00560 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00880 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D ACIS_00620 hemC; porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D ACIS_00505 hemD; uroporphyrinogen 3 synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D ACIS_00103 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D ACIS_00567 hemF; coproporphyrinogen 3 oxidase K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]
D ACIS_01196 hypothetical protein K08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-]
D ACIS_00418 ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D ACIS_00343 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D ACIS_01134 coxW; cytochrome C oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:acn00130]
D ACIS_00466 ubiA; prenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D ACIS_00141 ubiD; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D ACIS_00660 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxyl-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D ACIS_00740 ubiG; 3-demethylubiquinone-9 3-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64]
D ACIS_00112 ubiH; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]
D ACIS_00348 ubiE; ubiquinone/menaquinone biosynthesis methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D ACIS_00950 coq7; ubiquinone biosynthesis protein Coq7 K06134 COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:acn00900]
D ACIS_00584 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D ACIS_01202 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]
D ACIS_00811 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D ACIS_01201 ispF; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthetase (MECDP synthetase) K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]
D ACIS_00588 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D ACIS_00535 ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D ACIS_00660 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxyl-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D ACIS_00481 ispA; geranyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D ACIS_00192 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D ACIS_01143 uppS; undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D ACIS_00488 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:acn00261]
D ACIS_00346 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D ACIS_00124 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D ACIS_00892 dapA; dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D ACIS_00468 dapB; dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis
D ACIS_00829 inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
C 00333 Prodigiosin biosynthesis
D ACIS_01160 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D ACIS_00728 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D ACIS_00870 fabI; enoyl-[acyl-carrier-protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D ACIS_00958 acpP; acyl carrier protein AcpP K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites
D ACIS_00113 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
C 00627 Aminobenzoate degradation
D ACIS_00660 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxyl-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:acn03020]
D ACIS_01032 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D ACIS_01030 rpoC; DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D ACIS_00454 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D ACIS_00858 rpoZ; DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:acn03010]
D ACIS_00424 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D ACIS_00547 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D ACIS_00436 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D ACIS_00997 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D ACIS_00447 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D ACIS_01115 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D ACIS_01044 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D ACIS_00444 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D ACIS_00329 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D ACIS_00428 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D ACIS_00452 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D ACIS_01045 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D ACIS_00451 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D ACIS_00443 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D ACIS_00780 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D ACIS_00035 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D ACIS_00439 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D ACIS_01114 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D ACIS_00434 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D ACIS_00167 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D ACIS_01059 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D ACIS_01035 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D ACIS_00433 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D ACIS_00430 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D ACIS_00431 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D ACIS_00442 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D ACIS_00445 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D ACIS_01033 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D ACIS_01113 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D ACIS_01034 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D ACIS_01036 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D ACIS_00328 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D ACIS_00440 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D ACIS_00448 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D ACIS_00437 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D ACIS_00455 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D ACIS_00446 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D ACIS_00130 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D ACIS_00041 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D ACIS_00716 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D ACIS_00435 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D ACIS_00432 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D ACIS_00441 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D ACIS_00071 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D ACIS_00718 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D ACIS_00508 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D ACIS_00438 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D ACIS_01161 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D ACIS_00472 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D ACIS_00956 rpmG; 50 S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D ACIS_00461 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D ACIS_00042 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D ACIS_00721 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D ACIS_01352 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D ACIS_01353 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D ACIS_01351 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:acn00970]
D ACIS_01336 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D ACIS_01315 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01318 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01310 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01335 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01317 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D ACIS_01329 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D ACIS_01334 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D ACIS_01304 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D ACIS_01309 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D ACIS_01328 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D ACIS_01327 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D ACIS_01308 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D ACIS_01337 tRNA-His K14226 tRNA-His; tRNA His
D ACIS_01313 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D ACIS_01323 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01320 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01311 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01303 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01325 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01305 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D ACIS_01324 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D ACIS_01314 tRNA-Met K14230 tRNA-Met; tRNA Met
D ACIS_01326 tRNA-Met K14230 tRNA-Met; tRNA Met
D ACIS_01319 tRNA-Met K14230 tRNA-Met; tRNA Met
D ACIS_01316 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D ACIS_01312 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D ACIS_01301 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D ACIS_01302 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D ACIS_01330 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D ACIS_01333 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D ACIS_01331 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D ACIS_01332 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D ACIS_01322 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D ACIS_01307 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D ACIS_01321 tRNA-Val K14237 tRNA-Val; tRNA Val
D ACIS_01306 tRNA-Val K14237 tRNA-Val; tRNA Val
D ACIS_00054 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00560 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00622 gatA; glutamyl-tRNA amidotransferase chain A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D ACIS_00871 gatB; aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D ACIS_00322 putative tRNA amidotransferase K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D ACIS_01064 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D ACIS_01082 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D ACIS_00110 glyQ; glycyl-tRNA synthetase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D ACIS_00109 glyS; glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D ACIS_00128 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D ACIS_00569 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D ACIS_00821 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D ACIS_00347 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D ACIS_00988 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D ACIS_00223 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D ACIS_00854 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D ACIS_00630 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D ACIS_00647 lysK; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D ACIS_00636 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D ACIS_00798 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D ACIS_01136 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D ACIS_00040 pheS; phenylalanyl tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D ACIS_00456 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D ACIS_00196 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D ACIS_00012 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:acn03060]
D ACIS_00449 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D ACIS_01039 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D ACIS_00017 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D ACIS_00154 secD; preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D ACIS_00200 secF; preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D ACIS_00338 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D ACIS_00841 yidC; inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D ACIS_00249 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D ACIS_01156 secB; preprotein translocase subunit SecB K03071 secB; preprotein translocase subunit SecB
D ACIS_00499 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D ACIS_00243 ftsY; cell division protein (FtsY) K03110 ftsY; fused signal recognition particle receptor
D ACIS_00826 hypothetical protein K03117 tatB; sec-independent protein translocase protein TatB
D ACIS_00589 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
D ACIS_00614 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D ACIS_00282 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:acn04122]
D ACIS_00650 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00651 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00961 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D ACIS_00058 thiS; thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein
C 03050 Proteasome
C 03018 RNA degradation [PATH:acn03018]
D ACIS_00494 rne; ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D ACIS_00715 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D ACIS_00779 pnp; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D ACIS_00045 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D ACIS_00352 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D ACIS_01048 putative ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D ACIS_00495 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D ACIS_00394 groEL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D ACIS_00237 pcnB; poly (A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:acn03030]
D ACIS_00690 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D ACIS_01007 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D ACIS_00121 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D ACIS_00863 putative DNA polymerase III, subunit unknown K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D ACIS_00211 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D ACIS_00336 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D ACIS_00478 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D ACIS_00815 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D ACIS_00873 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ACIS_01147 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D ACIS_01029 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D ACIS_01124 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:acn03410]
D ACIS_00924 nth; endonuclease 3 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D ACIS_00676 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D ACIS_00164 putative DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D ACIS_00724 xth; exodeoxyribonuclease 3 K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D ACIS_00240 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D ACIS_01124 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:acn03420]
D ACIS_01148 mfd; transcription repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D ACIS_00844 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
D ACIS_00155 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
D ACIS_00916 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D ACIS_00935 uvrD; DNA helicase 2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D ACIS_01124 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:acn03430]
D ACIS_00887 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D ACIS_00966 mutL; DNA mismatch repair protein (MutL) K03572 mutL; DNA mismatch repair protein MutL
D ACIS_00935 uvrD; DNA helicase 2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D ACIS_00080 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D ACIS_01170 putative exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D ACIS_00240 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D ACIS_00873 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ACIS_01007 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D ACIS_00336 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D ACIS_00121 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D ACIS_00211 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D ACIS_00863 putative DNA polymerase III, subunit unknown K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D ACIS_00690 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D ACIS_01124 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:acn03440]
D ACIS_00240 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D ACIS_00873 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ACIS_00180 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
D ACIS_00635 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D ACIS_00907 recR; recombination protein RecR K06187 recR; recombination protein RecR
D ACIS_01184 recA; recombinase A K03553 recA; recombination protein RecA
D ACIS_01103 ruvA; holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
D ACIS_01104 ruvB; Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D ACIS_00105 ruvC; Holliday (crossover) junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D ACIS_00075 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D ACIS_01007 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D ACIS_00336 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D ACIS_00121 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D ACIS_00211 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D ACIS_00863 putative DNA polymerase III, subunit unknown K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D ACIS_00690 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D ACIS_00507 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:acn02010]
D ACIS_00061 putative ABC-type Fe3+ transport system protein K02012 afuA; iron(III) transport system substrate-binding protein
D ACIS_01053 putative transport protein K02011 afuB; iron(III) transport system permease protein
D ACIS_00908 ABC transporter, ATP-binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D ACIS_00248 putative ABC transporter K07323 mlaC; phospholipid transport system substrate-binding protein
D ACIS_00067 putative ABC transporter K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D ACIS_00188 putative ABC transporter K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D ACIS_00189 ribonucleotide transport ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D ACIS_01058 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D ACIS_01065 pstC; phosphate ABC transporter, permease protein K02037 pstC; phosphate transport system permease protein
D ACIS_00518 pstA; phosphate ABC transporter permease K02038 pstA; phosphate transport system permease protein
D ACIS_00469 pstB; phosphate ABC transporter K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D ACIS_00905 putative Zinc binding protein ZnuA K09815 znuA; zinc transport system substrate-binding protein
D ACIS_00550 putative zinc transporter protein ZnuB K09816 znuB; zinc transport system permease protein
D ACIS_00904 putative zinc transporter ATPase, ZnuC K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D ACIS_00212 lolE; lipoprotein releasing system, transmembrane protein K09808 lolC_E; lipoprotein-releasing system permease protein
D ACIS_00020 ABC transporter, ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D ACIS_01102 putative ABC-type transport system protein K02195 ccmC; heme exporter protein C
D ACIS_00246 ccmB; cytochrome c-type biogenesis protein/heme exporter protein K02194 ccmB; heme exporter protein B
D ACIS_01132 ccmA; cytochrome c biogenesis protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D ACIS_00408 putative ABC-type protease ArpD K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:acn03070]
D ACIS_00327 tolC; outer membrane protein TolC K12340 tolC; outer membrane protein
D ACIS_00154 secD; preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D ACIS_00200 secF; preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D ACIS_01039 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D ACIS_00017 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D ACIS_00449 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D ACIS_00338 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D ACIS_00841 yidC; inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D ACIS_00249 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D ACIS_00243 ftsY; cell division protein (FtsY) K03110 ftsY; fused signal recognition particle receptor
D ACIS_01156 secB; preprotein translocase subunit SecB K03071 secB; preprotein translocase subunit SecB
D ACIS_00499 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D ACIS_00826 hypothetical protein K03117 tatB; sec-independent protein translocase protein TatB
D ACIS_00589 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
D ACIS_00521 virB3; type IV secretion system protein VirB3 K03198 virB3; type IV secretion system protein VirB3
D ACIS_00091 virB9; type IV secretion system protein VirB9 K03204 virB9; type IV secretion system protein VirB9
D ACIS_01168 trbG; putative conjugal transfer protein TrbG K03204 virB9; type IV secretion system protein VirB9
D ACIS_00523 virB6; type IV secretion system protein VirB6 K03201 virB6; type IV secretion system protein VirB6
D ACIS_00524 putative type IV secretion system protein K03201 virB6; type IV secretion system protein VirB6
D ACIS_00526 putative plasmid conjugal transfer protein K03201 virB6; type IV secretion system protein VirB6
D ACIS_00530 putative conjugal transfer protein K03201 virB6; type IV secretion system protein VirB6
D ACIS_00090 virB8; type IV secretion system protein VirB8 K03203 virB8; type IV secretion system protein VirB8
D ACIS_00571 putative type IV secretion system protein VirB8 K03203 virB8; type IV secretion system protein VirB8
D ACIS_00092 virB10; type IV secretion system protein VirB10 K03195 virB10; type IV secretion system protein VirB10
D ACIS_00522 virB4; type IV secretion system protein VirB4 K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D ACIS_00304 type IV secretion system protein VirB4 K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D ACIS_00093 virB11; type IV secretion system protein VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D ACIS_00094 virD4; type IV secretion system protein VirD4 K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:acn02020]
D ACIS_01058 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D ACIS_00293 putative serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D ACIS_01134 coxW; cytochrome C oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D ACIS_00869 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein
D ACIS_00194 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01066 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01126 ntrY; nitrogen regulation protein NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D ACIS_01077 ntrX; nitrogen assimilation regulatory protein K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D ACIS_00973 barA; sensor histidine kinase K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
D ACIS_00827 pleD; response regulator K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
D ACIS_00333 putative response regulator K13584 ctrA; two-component system, cell cycle response regulator CtrA
D ACIS_00553 petA; ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D ACIS_00554 petB; cytochrome B K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D ACIS_00555 petC; ubiquinol-cytochrome c reductase, cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D ACIS_01090 cycM; cytochrome c K08738 CYC; cytochrome c
D ACIS_00327 tolC; outer membrane protein TolC K12340 tolC; outer membrane protein
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D ACIS_00553 petA; ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:acn02024]
D ACIS_00089 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D ACIS_00015 ribD; riboflavin biosynthesis protein K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D ACIS_00841 yidC; inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D ACIS_01039 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D ACIS_00017 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D ACIS_00449 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D ACIS_00338 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D ACIS_00249 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D ACIS_00243 ftsY; cell division protein (FtsY) K03110 ftsY; fused signal recognition particle receptor
D ACIS_01156 secB; preprotein translocase subunit SecB K03071 secB; preprotein translocase subunit SecB
D ACIS_00499 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
D ACIS_00814 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D ACIS_00715 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:acn01501]
D ACIS_00327 tolC; outer membrane protein TolC K12340 tolC; outer membrane protein
D ACIS_00201 putative cell division protein FtsI/penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D ACIS_00879 pbpA; penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:acn01502]
D ACIS_01079 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D ACIS_00533 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D ACIS_00193 mraY; phospho-n-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D ACIS_00831 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:acn01503]
D ACIS_00293 putative serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D ACIS_00327 tolC; outer membrane protein TolC K12340 tolC; outer membrane protein
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:acn01000]
C 01001 Protein kinases [BR:acn01001]
D ACIS_01126 ntrY; nitrogen regulation protein NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D ACIS_00973 barA; sensor histidine kinase K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:acn01009]
D ACIS_00922 htpG; heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
C 01002 Peptidases and inhibitors [BR:acn01002]
D ACIS_00282 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D ACIS_00208 guaA; bifunctional GMP synthase/glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D ACIS_00073 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D ACIS_00337 glmS; D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D ACIS_00283 putative peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
D ACIS_00284 putative peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
D ACIS_00385 pepA; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D ACIS_01192 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D ACIS_00276 map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D ACIS_00504 putative aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D ACIS_00487 putative metallocarboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D ACIS_00250 putative protease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D ACIS_00269 putative protease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D ACIS_00293 putative serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D ACIS_00272 dacA; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D ACIS_00991 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D ACIS_00989 lon; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D ACIS_00614 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D ACIS_00423 putative serine protease K04773 sppA; protease IV [EC:3.4.21.-]
D ACIS_00101 putative phage prohead protease K06904 GP4; Escherichia/Staphylococcus phage prohead protease
D ACIS_00351 hslV; ATP-dependent protease peptidase subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
D ACIS_00696 pmbA; peptidase pmbA K03592 pmbA; PmbA protein
D ACIS_01199 tldD; putative DNA gyrase control protein TldD K03568 tldD; TldD protein
D ACIS_00294 hflC; HflC protein K04087 hflC; modulator of FtsH protease HflC
D ACIS_00296 hflK; hflK protein K04088 hflK; modulator of FtsH protease HflK
C 01003 Glycosyltransferases
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:acn01011]
D ACIS_01131 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D ACIS_00619 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D ACIS_00011 murC; UDP-N-acetylmuramate-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D ACIS_01050 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D ACIS_01012 murE; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D ACIS_01079 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D ACIS_00193 mraY; phospho-n-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D ACIS_00831 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D ACIS_00170 mviN; uncharacterized membrane protein, putative virulence factor K03980 murJ; putative peptidoglycan lipid II flippase
D ACIS_00201 putative cell division protein FtsI/penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D ACIS_00879 pbpA; penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D ACIS_00272 dacA; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D ACIS_00262 slt; soluble lytic murein transglycosylase precursor K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D ACIS_00725 rlpA; rare lipoprotein A K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
C 01004 Lipid biosynthesis proteins [BR:acn01004]
D ACIS_01160 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D ACIS_00474 fabH; 3-oxoacyl-[acyl carrier protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D ACIS_00959 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D ACIS_00728 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D ACIS_00266 fabZ; (3R)-hydroxymyristoyl-ACP dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D ACIS_00870 fabI; enoyl-[acyl-carrier-protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D ACIS_01056 2-nitropropane dioxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D ACIS_00473 plsX; glycerol-3-phosphate acyltransferase/fatty acid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D ACIS_00106 hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D ACIS_00166 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:acn01006]
D ACIS_00481 ispA; geranyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D ACIS_00192 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D ACIS_01143 uppS; undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D ACIS_00573 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D ACIS_00466 ubiA; prenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D ACIS_00343 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:acn01007]
D ACIS_00647 lysK; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D ACIS_00054 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00560 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00196 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D ACIS_00012 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D ACIS_00821 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D ACIS_00636 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D ACIS_00347 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D ACIS_00630 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D ACIS_00223 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D ACIS_00854 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D ACIS_01082 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D ACIS_01136 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D ACIS_00110 glyQ; glycyl-tRNA synthetase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D ACIS_00109 glyS; glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D ACIS_00569 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D ACIS_00798 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D ACIS_00128 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D ACIS_01064 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D ACIS_00040 pheS; phenylalanyl tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D ACIS_00456 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D ACIS_00791 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D ACIS_00197 hemA; 5-aminolevulinate synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D ACIS_01024 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D ACIS_00974 argD; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D ACIS_00753 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:acn00194]
D ACIS_00640 atpC; F0F1-type ATP synthase, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D ACIS_00639 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D ACIS_00694 atpG; F0F1 ATP synthase subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D ACIS_00219 atpA; F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D ACIS_00217 atpH; ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D ACIS_00255 hypothetical protein K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D ACIS_00254 hypothetical protein K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D ACIS_00256 atpE; ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D ACIS_00258 atpA; ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:acn03000]
D ACIS_00911 birA; biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D ACIS_00730 putA; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D ACIS_01010 bolA; BolA-like protein K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D ACIS_00133 parB; chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D ACIS_00245 dksA; dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D ACIS_00066 nrdR; transcriptional regulator NrdR K07738 nrdR; transcriptional repressor NrdR
C 03021 Transcription machinery [BR:acn03021]
D ACIS_00454 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D ACIS_01032 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D ACIS_01030 rpoC; DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D ACIS_00858 rpoZ; DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D ACIS_00814 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
D ACIS_00671 rpoH; RNA polymerase sigma-32 factor K03089 rpoH; RNA polymerase sigma-32 factor
D ACIS_00592 nusA; transcription elongation factor K02600 nusA; transcription termination/antitermination protein NusA
D ACIS_00843 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D ACIS_01038 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG
D ACIS_00245 dksA; dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D ACIS_00220 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D ACIS_00045 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D ACIS_00352 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:acn03019]
D ACIS_00494 rne; ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D ACIS_00291 rnc; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D ACIS_01048 putative ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-]
D ACIS_00715 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D ACIS_00779 pnp; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D ACIS_00045 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D ACIS_00352 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D ACIS_00495 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D ACIS_00394 groEL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D ACIS_00237 pcnB; poly (A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
C 03041 Spliceosome
C 03011 Ribosome [BR:acn03011]
D ACIS_00424 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D ACIS_00547 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D ACIS_00436 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D ACIS_00997 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D ACIS_00447 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D ACIS_01115 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D ACIS_01044 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D ACIS_00444 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D ACIS_00329 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D ACIS_00428 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D ACIS_00452 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D ACIS_01045 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D ACIS_00451 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D ACIS_00443 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D ACIS_00780 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D ACIS_00035 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D ACIS_00439 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D ACIS_01114 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D ACIS_00434 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D ACIS_00167 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D ACIS_01059 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D ACIS_01035 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D ACIS_00433 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D ACIS_00430 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D ACIS_00431 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D ACIS_00442 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D ACIS_00445 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D ACIS_01113 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D ACIS_01034 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D ACIS_01036 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D ACIS_01033 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D ACIS_00328 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D ACIS_00440 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D ACIS_00448 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D ACIS_00437 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D ACIS_00455 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D ACIS_00446 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D ACIS_00130 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D ACIS_00041 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D ACIS_00716 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D ACIS_00435 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D ACIS_00432 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D ACIS_00441 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D ACIS_00718 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D ACIS_00508 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D ACIS_00438 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D ACIS_01161 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D ACIS_00472 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D ACIS_00956 rpmG; 50 S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D ACIS_00461 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D ACIS_00042 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D ACIS_00721 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D ACIS_00071 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D ACIS_01351 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D ACIS_01352 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D ACIS_01353 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:acn03009]
D ACIS_00291 rnc; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D ACIS_00500 era; GTP-binding protein Era K03595 era; GTPase
D ACIS_00714 obgE; GTPase ObgE K03979 obgE; GTPase [EC:3.6.5.-]
D ACIS_00245 dksA; dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D ACIS_00592 nusA; transcription elongation factor K02600 nusA; transcription termination/antitermination protein NusA
D ACIS_00843 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D ACIS_01038 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG
D ACIS_00751 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D ACIS_00052 putative methylase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D ACIS_00628 putative methyltransferase K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D ACIS_00712 mraW; S-adenosyl-methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D ACIS_00426 RNA methyltransferase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D ACIS_00681 ribosomal RNA methyltransferase RrmJ/FtsJ K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D ACIS_00828 rluC; ribosomal large subunit pseudouridine synthase C K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D ACIS_00509 putative pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D ACIS_00132 rimM; 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM
D ACIS_00494 rne; ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D ACIS_00483 putative Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D ACIS_00540 GTP-binding protein EngA K03977 engA; GTPase
D ACIS_00862 putative translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D ACIS_00595 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D ACIS_00362 hypothetical protein K09710 ybeB; ribosome-associated protein
D ACIS_00135 hypothetical protein K07042 ybeY; probable rRNA maturation factor
D ACIS_00670 putative ribosome-associated inhibitor A K05808 hpf; ribosome hibernation promoting factor
D ACIS_01200 ychF; translation-associated GTPase YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:acn03016]
D ACIS_00054 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00560 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00798 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D ACIS_00630 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D ACIS_00854 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D ACIS_00347 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D ACIS_00636 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D ACIS_01082 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D ACIS_01064 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D ACIS_00128 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D ACIS_00569 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D ACIS_00821 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D ACIS_00223 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D ACIS_01136 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D ACIS_00040 pheS; phenylalanyl tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D ACIS_00456 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D ACIS_00196 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D ACIS_00012 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D ACIS_00890 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D ACIS_00645 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D ACIS_00781 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D ACIS_00650 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00651 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00862 putative translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D ACIS_00573 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D ACIS_00077 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D ACIS_00376 tRNA uridine 5-carboxymethylaminomethyl modification enzyme K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D ACIS_00460 hypothetical protein K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D ACIS_00335 3'-5' exonuclease K03684 rnd; ribonuclease D [EC:3.1.13.5]
D ACIS_01125 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D ACIS_00647 lysK; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D ACIS_00110 glyQ; glycyl-tRNA synthetase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D ACIS_00109 glyS; glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D ACIS_00475 putative cytosine/adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D ACIS_00813 dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D ACIS_00900 putative 2-methylthioadenine synthetase K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D ACIS_00131 trmD; tRNA (guanine-1-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D ACIS_00961 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D ACIS_00653 putative Fe-S cluster assembly scaffold protein K13628 iscA; iron-sulfur cluster assembly protein
D ACIS_00225 aminomethyl transferase family protein K06980 ygfZ; tRNA-modifying protein YgfZ
D ACIS_00471 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D ACIS_00251 putative ATPase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D ACIS_00788 hypothetical protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D ACIS_00748 putative endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D ACIS_00126 putative uncharacterized P-loop hydrolase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D ACIS_00779 pnp; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:acn03012]
D ACIS_00594 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D ACIS_00095 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D ACIS_00127 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D ACIS_00548 tsf; elongation factor Ts K02357 tsf; elongation factor Ts
D ACIS_00427 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D ACIS_01040 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D ACIS_01042 fusA; translation elongation factor G K02355 fusA; elongation factor G
D ACIS_00563 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D ACIS_01144 frr; ribosome recycling factor K02838 frr; ribosome recycling factor
D ACIS_00279 putative HemK family modification methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D ACIS_00072 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D ACIS_00545 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D ACIS_00830 efp; translation elongation factor P K02356 efp; elongation factor P
D ACIS_00625 prfB; peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:acn03110]
D ACIS_00599 clpA; ATP-dependent clp protease ATP-binding subunit K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA
D ACIS_00390 ATP-dependent Clp protease ATP-binding subunit K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D ACIS_00990 clpX; ATP-dependent protease ATP-binding subunit K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D ACIS_00350 hslU; ATP-dependent protease ATP-binding subunit K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
D ACIS_00922 htpG; heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
D ACIS_00495 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D ACIS_00655 hscA; chaperone protein HscA K04044 hscA; molecular chaperone HscA
D ACIS_00394 groEL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D ACIS_00108 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D ACIS_00654 hscB; co-chaperone protein HscB K04082 hscB; molecular chaperone HscB
D ACIS_00013 grpE; putative GrpE protein K03687 GRPE; molecular chaperone GrpE
D ACIS_00395 groES; co-chaperonin GroES K04078 groES; chaperonin GroES
D ACIS_00293 putative serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D ACIS_00250 putative protease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D ACIS_00258 atpA; ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D ACIS_01156 secB; preprotein translocase subunit SecB K03071 secB; preprotein translocase subunit SecB
D ACIS_00790 putative peptidyl-prolyl cis-trans isomerase K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]
D ACIS_00053 hypothetical protein K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]
D ACIS_01169 trxA; thioredoxin K03671 TXN; thioredoxin
D ACIS_00280 grxC; glutaredoxin 3 K03676 grxC; glutaredoxin 3
D ACIS_01122 glutaredoxin-like protein GRLA K07390 grxD; monothiol glutaredoxin
D ACIS_01120 putative reductase K02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE
C 04131 Membrane trafficking [BR:acn04131]
D ACIS_00236 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D ACIS_00119 gap; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACIS_00922 htpG; heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
C 04121 Ubiquitin system [BR:acn04121]
C 03051 Proteasome [BR:acn03051]
D ACIS_00922 htpG; heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
C 03032 DNA replication proteins [BR:acn03032]
D ACIS_01147 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D ACIS_00864 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D ACIS_00007 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D ACIS_00422 putative integration host factor K05788 ihfB; integration host factor subunit beta
D ACIS_00869 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein
D ACIS_00478 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D ACIS_00815 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D ACIS_00873 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ACIS_01007 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D ACIS_00336 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D ACIS_00211 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D ACIS_00863 putative DNA polymerase III, subunit unknown K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D ACIS_00690 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D ACIS_00121 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D ACIS_01029 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D ACIS_01124 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D ACIS_00926 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D ACIS_00662 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D ACIS_00802 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:acn03036]
D ACIS_00291 rnc; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D ACIS_00864 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D ACIS_00007 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D ACIS_00422 putative integration host factor K05788 ihfB; integration host factor subunit beta
D ACIS_00869 dnaA; chromosomal replication initiation protein K02313 dnaA; chromosomal replication initiator protein
D ACIS_00253 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D ACIS_00879 pbpA; penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D ACIS_00980 cell divisionFtsK/SpoIIIE protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D ACIS_00713 hypothetical protein K03586 ftsL; cell division protein FtsL
D ACIS_01078 ftsQ; cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ
D ACIS_00114 ftsW; cell division protein FtsW K03588 ftsW; cell division protein FtsW
D ACIS_00137 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D ACIS_00420 hypothetical protein K09888 zapA; cell division protein ZapA
D ACIS_00417 putative ATPase K06916 zapE; cell division protein ZapE
D ACIS_00782 mreB; rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D ACIS_00783 mreC; rod shape-determining protein, MreC K03570 mreC; rod shape-determining protein MreC
D ACIS_00006 rodA; rod shape determining protein K05837 rodA; rod shape determining protein RodA
D ACIS_00134 soj; sporulation initiation inhibitor protein K03496 parA; chromosome partitioning protein
D ACIS_00133 parB; chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D ACIS_00376 tRNA uridine 5-carboxymethylaminomethyl modification enzyme K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D ACIS_00356 xerC; site-specific tyrosine recombinase K03733 xerC; integrase/recombinase XerC
D ACIS_00019 xerD; tyrosine recombinase K04763 xerD; integrase/recombinase XerD
D ACIS_00324 putative MRP-like protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D ACIS_00565 engB; GTPase EngB K03978 engB; GTP-binding protein
C 03400 DNA repair and recombination proteins [BR:acn03400]
D ACIS_00924 nth; endonuclease 3 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D ACIS_00534 dut; deoxyuridine 5'triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D ACIS_00164 putative DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D ACIS_00676 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D ACIS_00724 xth; exodeoxyribonuclease 3 K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D ACIS_00240 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D ACIS_01124 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D ACIS_00844 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
D ACIS_00155 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
D ACIS_00916 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D ACIS_00935 uvrD; DNA helicase 2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D ACIS_01032 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D ACIS_01030 rpoC; DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D ACIS_00454 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D ACIS_00858 rpoZ; DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D ACIS_01148 mfd; transcription repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D ACIS_00887 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D ACIS_00966 mutL; DNA mismatch repair protein (MutL) K03572 mutL; DNA mismatch repair protein MutL
D ACIS_00080 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D ACIS_01170 putative exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D ACIS_01007 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D ACIS_00336 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D ACIS_00211 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D ACIS_00863 putative DNA polymerase III, subunit unknown K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D ACIS_00690 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D ACIS_00121 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D ACIS_00873 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ACIS_01184 recA; recombinase A K03553 recA; recombination protein RecA
D ACIS_01103 ruvA; holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
D ACIS_01104 ruvB; Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D ACIS_00105 ruvC; Holliday (crossover) junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D ACIS_00507 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D ACIS_00617 msp3; major surface protein 3 K03546 sbcC; DNA repair protein SbcC/Rad50
D ACIS_01119 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
D ACIS_00180 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
D ACIS_00075 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D ACIS_00635 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D ACIS_00907 recR; recombination protein RecR K06187 recR; recombination protein RecR
D ACIS_00412 recB; putative exodeoxyribonuclease V K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D ACIS_00878 hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D ACIS_00926 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D ACIS_00662 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D ACIS_00802 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D ACIS_00864 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D ACIS_00007 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D ACIS_00422 putative integration host factor K05788 ihfB; integration host factor subunit beta
D ACIS_00482 nrdA; ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D ACIS_00820 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:acn03029]
D ACIS_00554 petB; cytochrome B K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D ACIS_00594 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D ACIS_00095 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D ACIS_00127 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D ACIS_00548 tsf; elongation factor Ts K02357 tsf; elongation factor Ts
D ACIS_00427 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D ACIS_01040 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D ACIS_01042 fusA; translation elongation factor G K02355 fusA; elongation factor G
D ACIS_00500 era; GTP-binding protein Era K03595 era; GTPase
D ACIS_00196 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D ACIS_00854 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D ACIS_01082 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D ACIS_00636 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D ACIS_00622 gatA; glutamyl-tRNA amidotransferase chain A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D ACIS_00871 gatB; aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D ACIS_00322 putative tRNA amidotransferase K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D ACIS_00873 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ACIS_00268 oma87; Outer membrane protein/protective antigen OMA87 K07277 SAM50; outer membrane protein insertion porin family
D ACIS_00495 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D ACIS_00013 grpE; putative GrpE protein K03687 GRPE; molecular chaperone GrpE
D ACIS_00394 groEL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D ACIS_00395 groES; co-chaperonin GroES K04078 groES; chaperonin GroES
D ACIS_00108 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D ACIS_00650 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00651 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00656 fdx; ferredoxin K22071 FDX2; ferredoxin-2, mitochondrial
D ACIS_00654 hscB; co-chaperone protein HscB K04082 hscB; molecular chaperone HscB
D ACIS_01122 glutaredoxin-like protein GRLA K07390 grxD; monothiol glutaredoxin
D ACIS_00777 putative methyltransferase K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D ACIS_00324 putative MRP-like protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D ACIS_00343 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D ACIS_00290 ctaG; cytochrome C oxidase assembly protein K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D ACIS_01134 coxW; cytochrome C oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D ACIS_00841 yidC; inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D ACIS_00261 surf1; surfeit locus protein 1 K14998 SURF1; surfeit locus 1 family protein
D ACIS_01057 msp5; major surface protein 5 K07152 SCO1; protein SCO1
D ACIS_00922 htpG; heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:acn02000]
D ACIS_01109 ABC transporter K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D ACIS_00408 putative ABC-type protease ArpD K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
D ACIS_00061 putative ABC-type Fe3+ transport system protein K02012 afuA; iron(III) transport system substrate-binding protein
D ACIS_01053 putative transport protein K02011 afuB; iron(III) transport system permease protein
D ACIS_00908 ABC transporter, ATP-binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D ACIS_00067 putative ABC transporter K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D ACIS_00188 putative ABC transporter K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D ACIS_00189 ribonucleotide transport ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D ACIS_00248 putative ABC transporter K07323 mlaC; phospholipid transport system substrate-binding protein
D ACIS_01058 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D ACIS_01065 pstC; phosphate ABC transporter, permease protein K02037 pstC; phosphate transport system permease protein
D ACIS_00518 pstA; phosphate ABC transporter permease K02038 pstA; phosphate transport system permease protein
D ACIS_00469 pstB; phosphate ABC transporter K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D ACIS_00905 putative Zinc binding protein ZnuA K09815 znuA; zinc transport system substrate-binding protein
D ACIS_00550 putative zinc transporter protein ZnuB K09816 znuB; zinc transport system permease protein
D ACIS_00904 putative zinc transporter ATPase, ZnuC K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D ACIS_00212 lolE; lipoprotein releasing system, transmembrane protein K09808 lolC_E; lipoprotein-releasing system permease protein
D ACIS_00020 ABC transporter, ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D ACIS_01102 putative ABC-type transport system protein K02195 ccmC; heme exporter protein C
D ACIS_00246 ccmB; cytochrome c-type biogenesis protein/heme exporter protein K02194 ccmB; heme exporter protein B
D ACIS_01132 ccmA; cytochrome c biogenesis protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D ACIS_00034 putative transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D ACIS_00884 putative transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D ACIS_00875 putative transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D ACIS_00877 putative transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D ACIS_00883 putative transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D ACIS_01105 bcr; bicyclomycin resistance protein K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein
D ACIS_00910 gst; glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D ACIS_00685 mgtE; magnesium transporter K06213 mgtE; magnesium transporter
D ACIS_00969 tolQ; TolQ protein K03562 tolQ; biopolymer transport protein TolQ
D ACIS_00970 tolR; TolR protein K03560 tolR; biopolymer transport protein TolR
D ACIS_00984 putative transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
D ACIS_00327 tolC; outer membrane protein TolC K12340 tolC; outer membrane protein
D ACIS_00268 oma87; Outer membrane protein/protective antigen OMA87 K07277 SAM50; outer membrane protein insertion porin family
D ACIS_00541 hypothetical protein K17713 bamB; outer membrane protein assembly factor BamB
D ACIS_00341 putative DNA uptake lipoprotein ComL K05807 bamD; outer membrane protein assembly factor BamD
D ACIS_00247 czcD; putative Co/Zn/Cd efflux system component CzcD K16264 czcD; cobalt-zinc-cadmium efflux system protein
D ACIS_00590 AcrB/AcrD/AcrF family cation efflux protein K18989 vexF; multidrug efflux pump
D ACIS_01194 kefB; glutathione-regulated potassium-efflux system protein K03455 KEA1_2_3; K+:H+ antiporter
D ACIS_00252 trkH; potassium uptake protein K03498 trkH; trk/ktr system potassium uptake protein
D ACIS_00491 putative monovalent cation/H+ antiporter subunit B K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D ACIS_00492 putative monovalent cation/H+ antiporter K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D ACIS_00493 putative monovalent cation/H+ antiporter K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D ACIS_00027 putative monovalent cation/H+ antiporter subunit D K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D ACIS_00498 putative monovalent cation/H+ antiporter subunit D K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D ACIS_01088 nuoL; NADH dehydrogenase I chain L K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D ACIS_01022 putative monovalent cation/H+ antiporter K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D ACIS_00489 putative monovalent cation/H+ antiporter subunit F K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D ACIS_00490 putative monovalent cation/H+ antiporter subunit G K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D ACIS_00170 mviN; uncharacterized membrane protein, putative virulence factor K03980 murJ; putative peptidoglycan lipid II flippase
D ACIS_01172 putative permease K24180 mleP; malate permease and related proteins
D ACIS_00114 ftsW; cell division protein FtsW K03588 ftsW; cell division protein FtsW
D ACIS_00486 putative outer membrane protein OmpA K03640 pal; peptidoglycan-associated lipoprotein
D ACIS_01049 tolB; translocation protein K03641 tolB; TolB protein
D ACIS_01052 putative secretion protein K12537 hasE; membrane fusion protein, type I secretion system
D ACIS_00544 putative membrane-fusion protein K18990 vexE; membrane fusion protein, multidrug efflux system
D ACIS_00224 ccmF; cytochrome c-type biogenesis protein K02198 ccmF; cytochrome c-type biogenesis protein CcmF
C 02044 Secretion system [BR:acn02044]
D ACIS_00327 tolC; outer membrane protein TolC K12340 tolC; outer membrane protein
D ACIS_00408 putative ABC-type protease ArpD K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
D ACIS_01052 putative secretion protein K12537 hasE; membrane fusion protein, type I secretion system
D ACIS_00960 putative twitching motility protein K02669 pilT; twitching motility protein PilT
D ACIS_00982 YGGT family protein K02221 yggT; YggT family protein
D ACIS_00457 putative competence protein K02238 comEC; competence protein ComEC
D ACIS_00521 virB3; type IV secretion system protein VirB3 K03198 virB3; type IV secretion system protein VirB3
D ACIS_00522 virB4; type IV secretion system protein VirB4 K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D ACIS_00304 type IV secretion system protein VirB4 K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D ACIS_00523 virB6; type IV secretion system protein VirB6 K03201 virB6; type IV secretion system protein VirB6
D ACIS_00524 putative type IV secretion system protein K03201 virB6; type IV secretion system protein VirB6
D ACIS_00526 putative plasmid conjugal transfer protein K03201 virB6; type IV secretion system protein VirB6
D ACIS_00530 putative conjugal transfer protein K03201 virB6; type IV secretion system protein VirB6
D ACIS_00090 virB8; type IV secretion system protein VirB8 K03203 virB8; type IV secretion system protein VirB8
D ACIS_00571 putative type IV secretion system protein VirB8 K03203 virB8; type IV secretion system protein VirB8
D ACIS_00091 virB9; type IV secretion system protein VirB9 K03204 virB9; type IV secretion system protein VirB9
D ACIS_01168 trbG; putative conjugal transfer protein TrbG K03204 virB9; type IV secretion system protein VirB9
D ACIS_00092 virB10; type IV secretion system protein VirB10 K03195 virB10; type IV secretion system protein VirB10
D ACIS_00093 virB11; type IV secretion system protein VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D ACIS_00094 virD4; type IV secretion system protein VirD4 K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
D ACIS_00249 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D ACIS_01156 secB; preprotein translocase subunit SecB K03071 secB; preprotein translocase subunit SecB
D ACIS_00154 secD; preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D ACIS_01039 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D ACIS_00200 secF; preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D ACIS_00017 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D ACIS_00449 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D ACIS_00499 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D ACIS_00243 ftsY; cell division protein (FtsY) K03110 ftsY; fused signal recognition particle receptor
D ACIS_00338 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D ACIS_00841 yidC; inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D ACIS_00826 hypothetical protein K03117 tatB; sec-independent protein translocase protein TatB
D ACIS_00589 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:acn02042]
D ACIS_00984 putative transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:acn02022]
D ACIS_01126 ntrY; nitrogen regulation protein NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D ACIS_01077 ntrX; nitrogen assimilation regulatory protein K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D ACIS_00973 barA; sensor histidine kinase K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
D ACIS_00827 pleD; response regulator K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
D ACIS_00333 putative response regulator K13584 ctrA; two-component system, cell cycle response regulator CtrA
C 02035 Bacterial motility proteins [BR:acn02035]
D ACIS_00960 putative twitching motility protein K02669 pilT; twitching motility protein PilT
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:acn04812]
D ACIS_00782 mreB; rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D ACIS_00137 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D ACIS_00253 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D ACIS_00134 soj; sporulation initiation inhibitor protein K03496 parA; chromosome partitioning protein
D ACIS_00133 parB; chromosome partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:acn04147]
D ACIS_00922 htpG; heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
D ACIS_00715 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D ACIS_00119 gap; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D ACIS_00081 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D ACIS_00793 peroxiredoxin (PRX) family protein K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D ACIS_00394 groEL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D ACIS_00495 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D ACIS_01164 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D ACIS_00427 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D ACIS_01040 tuf; translation elongation factor Tu K02358 tuf; elongation factor Tu
D ACIS_00890 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D ACIS_00450 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D ACIS_00194 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_01066 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D ACIS_00880 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D ACIS_00265 purH; bifunctional phosphoribosylaminoimidazole carboxamide formyltransferase-IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D ACIS_00543 lpdA; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_01074 pdhD; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D ACIS_00750 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:acn02048]
D ACIS_00137 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D ACIS_00782 mreB; rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D ACIS_00054 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00560 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ACIS_00270 hypothetical protein K09159 cptB; antitoxin CptB
D ACIS_00650 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ACIS_00651 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:acn01504]
D ACIS_00327 tolC; outer membrane protein TolC K12340 tolC; outer membrane protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:acn03100]
D ACIS_01336 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D ACIS_01315 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01318 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01310 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01335 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D ACIS_01317 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D ACIS_01329 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D ACIS_01334 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D ACIS_01304 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D ACIS_01309 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D ACIS_01328 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D ACIS_01327 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D ACIS_01308 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D ACIS_01337 tRNA-His K14226 tRNA-His; tRNA His
D ACIS_01313 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D ACIS_01323 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01320 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01311 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01303 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01325 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D ACIS_01305 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D ACIS_01324 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D ACIS_01314 tRNA-Met K14230 tRNA-Met; tRNA Met
D ACIS_01326 tRNA-Met K14230 tRNA-Met; tRNA Met
D ACIS_01319 tRNA-Met K14230 tRNA-Met; tRNA Met
D ACIS_01316 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D ACIS_01312 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D ACIS_01301 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D ACIS_01302 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D ACIS_01330 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D ACIS_01333 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D ACIS_01331 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D ACIS_01332 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D ACIS_01322 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D ACIS_01307 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D ACIS_01321 tRNA-Val K14237 tRNA-Val; tRNA Val
D ACIS_01306 tRNA-Val K14237 tRNA-Val; tRNA Val
D ACIS_01352 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D ACIS_01353 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D ACIS_01351 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
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A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D ACIS_00411 qor; quinone oxidoreductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D ACIS_00629 putative peroxiredoxin K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D ACIS_00169 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D ACIS_00986 hypothetical protein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]
D ACIS_00852 putative DNase, TatD K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D ACIS_00165 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D ACIS_01017 putative polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D ACIS_01100 putative deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D ACIS_00803 putative sugar kinase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D ACIS_00274 putative hexapeptide transferase family protein K01726 GAMMACA; gamma-carbonic anhydrase [EC:4.2.1.-]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D ACIS_00097 fdxA; ferredoxin K05524 fdxA; ferredoxin
D ACIS_00652 nifU; scaffold protein K04488 iscU; nitrogen fixation protein NifU and related proteins
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
D ACIS_00902 putative kinase K03688 ubiB; ubiquinone biosynthesis protein
D ACIS_01051 COQ9 domain containing protein K18587 COQ9; ubiquinone biosynthesis protein COQ9
D ACIS_00496 putative oligoketide cyclase/lipid transport protein K18588 COQ10; coenzyme Q-binding protein COQ10
C 99988 Secondary metabolism
C 99999 Others
D ACIS_01016 putative esterase K06999 K06999; phospholipase/carboxylesterase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D ACIS_01127 putative cold-shock protein K03704 cspA; cold shock protein
C 99974 Translation
C 99975 Protein processing
D ACIS_00992 tig; trigger factor K03545 tig; trigger factor
D ACIS_00222 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D ACIS_00689 putative ATPase K07391 comM; magnesium chelatase family protein
C 99976 Replication and repair
D ACIS_00396 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC
D ACIS_00570 putative DNA recombination protein RmuC K09760 rmuC; DNA recombination protein RmuC
D ACIS_00199 hypothetical protein K07460 yraN; putative endonuclease
D ACIS_00963 putativeDNA recombination-mediator protein A K04096 smf; DNA processing protein
D ACIS_00501 putative 3'-5' exonuclease K07501 K07501; 3'-5' exonuclease
C 99979 Viral proteins
C 99998 Others
D ACIS_00123 hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D ACIS_00459 sodium:alanine symporter family protein K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family
C 99978 Cell growth
C 99993 Cell motility
C 99995 Signaling proteins
D ACIS_00600 typA; GTP-binding protein TypA K06207 typA; GTP-binding protein
C 99992 Structural proteins
D ACIS_00373 putative peptidase K06194 nlpD; lipoprotein NlpD
D ACIS_00850 ccmE; cytochrome c-type biogenesis protein K02197 ccmE; cytochrome c-type biogenesis protein CcmE
D ACIS_00658 hypothetical protein K02200 ccmH; cytochrome c-type biogenesis protein CcmH
C 99994 Others
D ACIS_00808 cutA; periplasmic divalent cation tolerance protein K03926 cutA; periplasmic divalent cation tolerance protein
D ACIS_00319 apaG; putative ApaG protein K06195 apaG; ApaG protein
D ACIS_01110 frataxin domain containing protein K06202 cyaY; iron-sulfur cluster assembly protein CyaY
B
B 09194 Poorly characterized
C 99996 General function prediction only
D ACIS_01116 putative membrane protein K03558 cvpA; membrane protein required for colicin V production
D ACIS_00613 putative Fe-S protein K15724 erpA; iron-sulfur cluster insertion protein
D ACIS_00754 putative ribonuclease K07058 K07058; membrane protein
D ACIS_00987 rhodanese domain-containing protein K07146 K07146; UPF0176 protein
C 99997 Function unknown
D ACIS_00414 ankyrin repeat domain containing protein K06867 K06867; uncharacterized protein
D ACIS_00125 putative BAX inhibitor (BI)-1 like protein K06890 K06890; uncharacterized protein
D ACIS_00649 putative hydrolase K07018 K07018; uncharacterized protein
D ACIS_00749 putative transport protein K07080 K07080; uncharacterized protein
D ACIS_00801 hypothetical protein K09985 K09985; uncharacterized protein
D ACIS_00044 hypothetical protein K09987 K09987; uncharacterized protein
D ACIS_00326 hypothetical protein K09991 K09991; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: October 3, 2024