+E Transcription factors KO
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Transcription Factors - Apis mellifera (honey bee)
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
D 408853 X-box-binding protein 1 isoform X1 K09027 XBP1; X box-binding protein 1
D 726289 transcription factor AP-1 K04448 JUN; transcription factor AP-1
C AP-1(-like) components, Fos
D 724169 transcription factor kayak isoform X1 K09031 FOSLN; fos-like antigen, invertebrate
D 408981 activating transcription factor 3 isoform X2 K21406 ATF3; activating transcription factor 3
C AP-1(-like) components, Maf
D 724861 transcription factor Maf isoform X2 K09035 CMAF; transcription factor Maf
D 726492 transcription factor MafG K09037 MAFF_G_K; transcription factor MAFF/G/K
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
D 100576527 cyclic AMP-dependent transcription factor ATF-2 isoform X1 K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
D 410226 activating transcription factor of chaperone isoform X2 K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
C CREB
D 409401 cyclic AMP-responsive element-binding protein 1 isoform X1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 100576912 cyclic AMP response element-binding protein A K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 726184 uncharacterized protein LOC726184 K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 412432 uncharacterized protein LOC412432 isoform X1 K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
C C/EBP-like factors
D 726550 CCAAT/enhancer-binding protein gamma K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
D 411207 CCAAT/enhancer-binding protein K10052 CEBPN; CCAAT/enhancer binding protein (C/EBP), invertebrate
C bZIP/PAR
D 726528 nuclear factor interleukin-3-regulated protein K09056 DBP; albumin D box-binding protein
D 408449 thyrotroph embryonic factor isoform X4 K09057 HLF; hepatic leukemia factor
C Plant bZIP factors
C ZIP only
D 410253 ataxin-2 homolog isoform X2 K12114 VRI; vrille
D 725191 protein giant isoform X1 K09062 GT; protein giant
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
D 410553 POU domain, class 4, transcription factor 1 K15603 TCF4_12; transcription factor 4/12
C Myogenic transcription factors
D 724636 uncharacterized protein LOC724636 isoform X1 K18484 MYF5; myogenic factor 5
C Achaete-Scute
D 724458 achaete-scute complex protein T3 K09067 ASCL; achaete-scute complex protein
D 100578780 helix-loop-helix protein delilah K09067 ASCL; achaete-scute complex protein
C Tal/Twist/Atonal/Hen, Lymphoid factors
D 725127 uncharacterized protein LOC725127 isoform X2 K09068 TAL; T-cell acute lymphocytic leukemia protein
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
D 413254 Twi; twist K09069 TWIST; twist
D 113219217 transcription factor 15-like K09070 TCF15; transcription factor 15
D 100576222 heart- and neural crest derivatives-expressed protein 1 K18486 HAND2; heart-and neural crest derivatives-expressed protein 2
D 100576215 pancreas transcription factor 1 subunit alpha isoform X3 K09073 PTF1A; pancreas-specific transcription factor 1a
D 107965534 protein Fer3-like isoform X1 K22400 FERD3L; Fer3-like protein
C Tal/Twist/Atonal/Hen, HEN
D 102653654 helix-loop-helix protein 1-like K09075 NHLH; nescient helix-loop-helix protein
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
D 725085 basic helix-loop-helix neural transcription factor TAP K09081 NEUROG1; neurogenin 1
D 102656766 uncharacterized protein LOC102656766 K09083 ATOH1_7; atonal protein 1/7
D 100576434 protein atonal K09083 ATOH1_7; atonal protein 1/7
D 102656170 protein atonal K09083 ATOH1_7; atonal protein 1/7
D 100577795 probable serine/threonine-protein kinase DDB_G0282963 K09084 ATOH8; atonal protein 8
D 100576700 class A basic helix-loop-helix protein 15 isoform X1 K08040 BHLHB8; class B basic helix-loop-helix protein 8
D 107964774 class A basic helix-loop-helix protein 15 K08040 BHLHB8; class B basic helix-loop-helix protein 8
C Tal/Twist/Atonal/Hen, Pancreatic factors
D 726594 class E basic helix-loop-helix protein 23 K09086 BHLHB4_5; class B basic helix-loop-helix protein 4/5
C Hairy, Hairy/E(SPL)
D 409822 enhancer of split m7 protein K09090 HESN; hairy and enhancer of split, invertebrate
D 410468 protein hairy K09090 HESN; hairy and enhancer of split, invertebrate
D 724914 protein hairy K09090 HESN; hairy and enhancer of split, invertebrate
D 100578067 enhancer of split mgamma protein K09090 HESN; hairy and enhancer of split, invertebrate
D 724465 enhancer of split mbeta protein K09090 HESN; hairy and enhancer of split, invertebrate
D 100577069 hairy/enhancer-of-split related with YRPW motif protein K09091 HEY; hairy and enhancer of split related with YRPW motif
D 726204 transcription factor cwo isoform X3 K27237 CWO; transcription factor CWO
C Hairy, Fungal regulators
C Factors with PAS domain
D 411264 aryl hydrocarbon receptor protein 1 isoform X1 K09093 AHR; aryl hydrocarbon receptor
D 408852 uncharacterized protein LOC408852 isoform X1 K08268 HIF1A; hypoxia-inducible factor 1 alpha
D 411234 aryl hydrocarbon receptor nuclear translocator homolog isoform X1 K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
D 552367 neuronal PAS domain-containing protein 4 isoform X1 K26457 NPAS4; neuronal PAS domain-containing protein 4
D 410757 circadian locomoter output cycles protein kaput isoform X1 K02223 CLOCK; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
D 725614 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1 K02296 ARNTL; aryl hydrocarbon receptor nuclear translocator-like protein 1
D 410669 single-minded homolog 2 isoform X2 K09100 SIM; single-minded
C Yabby
C INO
C HLH domain only
D 100216325 Emc; extra macrochaetae K17696 EMC; DNA-binding protein inhibitor ID, other
D 410694 transcription factor collier isoform X1 K09103 EBF; early B-cell factor
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
D 410802 microphthalmia-associated transcription factor isoform X1 K09455 MITF; microphthalmia-associated transcription factor
D 551264 upstream stimulatory factor 1 isoform X2 K09106 USF; upstream stimulatory factor
D 551590 upstream stimulatory factor 1 K09106 USF; upstream stimulatory factor
D 726729 helix-loop-helix protein 11 K09108 TFAP4; transcription factor AP-4
C Cell cycle controlling factors, Myc
D 100576392 transcriptional regulator Myc-B isoform X2 K04377 MYC; Myc proto-oncogene protein
C Cell cycle controlling factors, Mad/Max
D 551131 protein max isoform X2 K04453 MAX; Max protein
D 410953 MLX-interacting protein isoform X2 K09113 MLX; MAX-like protein X
D 412452 max-like protein X K09113 MLX; MAX-like protein X
D 724047 Mad; MAX dimerization protein K09114 MXD; MAX dimerization protein
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
D 410259 nuclear factor 1 X-type isoform X2 K09172 NFIN; nuclear factor I, invertebrate
C RF-X
D 411674 DNA-binding protein RFX2 isoform X1 K09173 RFX1_2_3; regulatory factor X 1/2/3
D 724622 DNA-binding protein RFX7 K09175 RFX7; DNA-binding protein RFX7
C AP-2 (bHSH)
D 410893 transcription factor AP-2-epsilon isoform X1 K09180 TFAP2N; transcription factor AP-2, invertebrate
B Zinc finger
C Cys4 thyroid hormone receptor-like
D 413076 ecdysone-induced protein 78C isoform X2 K08701 NR1D3; nuclear receptor subfamily 1 group D member 3
D 408586 probable nuclear hormone receptor HR3 isoform X1 K14033 NR1F4; nuclear receptor subfamily 1 group F member 4
D 406084 Ecr; ecdysone receptor isoform A K14034 NR1H1; ecdysone receptor
D 551825 nuclear hormone receptor HR96 isoform X2 K14035 NR1IN; nuclear receptor subfamily 1 group I
C Cys4 hepatocyte nuclear factor 4-like
D 102655120 hepatocyte nuclear factor 4-gamma isoform X1 K08704 NR2A4; hepatocyte nuclear factor 4
D 102654580 nuclear receptor subfamily 2 group E member 1-like isoform X1 K07295 NR2AN; nuclear receptor subfamily 2 group A
D 725327 nuclear receptor subfamily 2 group E member 1 K08545 NR2E1; nuclear receptor subfamily 2 group E member 1
D 413558 photoreceptor-specific nuclear receptor K08546 NR2E3; nuclear receptor subfamily 2 group E member 3
D 551649 nuclear receptor subfamily 2 group F member 6 K08546 NR2E3; nuclear receptor subfamily 2 group E member 3
D 408872 COUP transcription factor 2 K14032 NR2F3; nuclear receptor subfamily 2 group F member 3
C Cys4 estrogen receptor-like
D 408855 Err; estrogen-related receptor K08703 NR3BN; estrogen-related receptor ERR
C Cys4 nerve growth factor IB-like
D 551232 probable nuclear hormone receptor HR38 K08558 NR4A2; nuclear receptor subfamily 4 group A member 2
C Cys4 Fushi tarazu-F1-like
D 413474 nuclear hormone receptor FTZ-F1 beta K08705 NR5A3; nuclear receptor subfamily 5 group A member 3
D 726450 nuclear hormone receptor FTZ-F1 K08705 NR5A3; nuclear receptor subfamily 5 group A member 3
C Cys4 germ cell nuclear factor
D 410925 hormone receptor 4 isoform X1 K09185 NR6AN; nuclear receptor subfamily 6 group A
C Cys4 Knirps/DAX1-like
D 724640 nuclear receptor subfamily 1 group D member 2 isoform X1 K08706 NR0AN; nuclear receptor subfamily 0 group A
D 412475 knirps-related protein K08706 NR0AN; nuclear receptor subfamily 0 group A
D 724765 protein embryonic gonad isoform X2 K08706 NR0AN; nuclear receptor subfamily 0 group A
C Cys4 GATA-factors
D 100577332 GATA-binding factor C isoform X1 K17894 GATA2; GATA-binding protein 2
D 725350 GATA-binding factor A K09183 GATA4; GATA-binding protein 4
D 410102 GATA zinc finger domain-containing protein 1 K23407 GATAD1; GATA zinc finger domain-containing protein 1
D 552094 transcriptional repressor p66-beta isoform X1 K23194 GATAD2; transcriptional repressor p66
D 409084 arginine-glutamic acid dipeptide repeats protein isoform X2 K05628 RERE; arginine-glutamic acid dipeptide repeats protein
D 413318 metastasis-associated protein MTA3 isoform X1 K11660 MTA; metastasis-associated protein MTA
D 410798 Dnmt3; DNA methyltransferase 3 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 724593 transcriptional regulator ATRX homolog isoform X1 K10779 ATRX; transcriptional regulator ATRX
C Cys2His2 SP/KLF family and related proteins
D 724156 transcription factor Sp8-like K09195 SP5; transcription factor Sp5
D 551928 transcription factor Sp4 K09200 SP-N; transcription factor Sp, invertebrate
D 725885 Krueppel-like factor 7 K09207 KLF6_7; krueppel-like factor 6/7
D 552397 Krueppel-like factor 6 isoform X3 K09205 KLF8_12; krueppel-like factor 8/12
D 100576307 oocyte zinc finger protein XlCOF8.4 isoform X2 K09210 KLF15; krueppel-like factor 15
D 726302 alpha-protein kinase 1 isoform X1 K09203 EGR1; early growth response protein 1
D 100578561 early growth response protein 1 K12379 HKB; huckebein
C Cys2His2 GLI-like
D 100576110 zinc finger protein GLI4 isoform X1 K09232 GLIS1_3; zinc finger protein GLIS1/3
D 100578226 zinc finger protein GLI1 K09233 GLIS2; zinc finger protein GLIS2
D 100578824 zinc finger protein ZIC 4 K09227 ZICN; zinc finger protein ZIC, invertebrate
D 551746 transcriptional activator cubitus interruptus isoform X2 K16799 CI; transcriptional activator cubitus interruptus
C Cys2His2 Snail
D 410464 escargot/snail protein homolog K05706 SNAI2; snail 2
D 100576293 zinc finger protein 182 K09219 SCRT; scratch
D 725965 insulinoma-associated protein 1-like K25795 INSM; insulinoma-associated protein
C Cys2His2 BTB-ZF factors
D 551360 transcription factor Ken isoform X2 K10516 ZBTB45; zinc finger and BTB domain-containing protein 45
D 410918 protein tramtrack, alpha isoform isoform X1 K09237 TTK; tramtrack
D 552255 Br-c; broad-complex K02174 BR-C; broad-complex core protein
D 102654975 protein bric-a-brac 1-like isoform X1 K27896 K27896; TTK-type BTB protein
D 411126 protein bric-a-brac 2 isoform X1 K27896 K27896; TTK-type BTB protein
D 724893 zinc finger and BTB domain-containing protein 44 isoform X1 K27896 K27896; TTK-type BTB protein
D 406123 Psq; pipsqueak K27896 K27896; TTK-type BTB protein
D 410107 broad-complex core protein isoforms 1/2/3/4/5 isoform X2 K27896 K27896; TTK-type BTB protein
D 551432 zinc finger and BTB domain-containing protein 20 isoform X2 K27896 K27896; TTK-type BTB protein
D 725336 longitudinals lacking protein, isoforms A/B/D/L isoform X1 K27896 K27896; TTK-type BTB protein
D 552090 transcription factor GAGA isoform X1 K27896 K27896; TTK-type BTB protein
D 726547 protein abrupt isoform X1 K27896 K27896; TTK-type BTB protein
D 725311 longitudinals lacking protein-like K27896 K27896; TTK-type BTB protein
D 551086 zinc finger protein chinmo isoform X1 K27896 K27896; TTK-type BTB protein
D 725189 protein bric-a-brac 2 isoform X1 K27896 K27896; TTK-type BTB protein
D 727269 zinc finger protein 271 isoform X2 K27896 K27896; TTK-type BTB protein
D 409022 LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 34 K27896 K27896; TTK-type BTB protein
D 113219102 sex determination protein fruitless-like K27896 K27896; TTK-type BTB protein
D 412161 broad-complex core protein isoforms 1/2/3/4/5 isoform X3 K27896 K27896; TTK-type BTB protein
D 724810 probable serine/threonine-protein kinase dyrk2 K27896 K27896; TTK-type BTB protein
C Cys2His2 BED
D 727528 zinc finger BED domain-containing protein 1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C Cys2His2 PRDM
D 408295 probable serine/threonine-protein kinase DDB_G0282963 isoform X1 K24501 PRDM1; PR domain zinc finger protein 1 [EC:2.1.1.-]
D 725792 transcription factor hamlet-like isoform X1 K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
D 724908 Krueppel-like factor 11 K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
D 412574 PR domain zinc finger protein 10 isoform X1 K24643 PRDM10; PR domain zinc finger protein 10 [EC:2.1.1.-]
D 102656356 zinc finger protein SNAI2 K24645 PRDM13; PR domain zinc finger protein 13 [EC:2.1.1.-]
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
D 410399 protein bowel K09215 OSR; odd-skipped
D 725053 protein odd-skipped K09215 OSR; odd-skipped
D 725003 protein sister of odd and bowel K09215 OSR; odd-skipped
D 113218532 protein bowel-like K09215 OSR; odd-skipped
D 113219211 protein sister of odd and bowel-like K09215 OSR; odd-skipped
D 552100 transcriptional regulator ovo isoform X1 K09216 OVOL; ovo
D 410222 zinc finger protein 853 isoform X1 K09221 MZF1; myeloid zinc finger protein 1
D 100577543 fez family zinc finger protein 1 K09223 GFI1; growth factor independent 1
D 102655131 zinc finger protein 300-like K09223 GFI1; growth factor independent 1
D 552030 uncharacterized protein LOC552030 K09239 HIVEP; human immunodeficiency virus type I enhancer-binding protein
D 408661 uncharacterized protein LOC408661 isoform X1 K17452 AEBP2; zinc finger protein AEBP2
D 100577174 ras-responsive element-binding protein 1 isoform X1 K20210 RREB1; ras-responsive element-binding protein 1
D 724150 B-cell lymphoma/leukemia 11B isoform X2 K22045 BCL11A; B-cell lymphoma/leukemia 11A
D 100576586 transcriptional repressor CTCFL-like isoform X1 K23195 CTCF; transcriptional repressor CTCF
D 100577672 probable serine/threonine-protein kinase DDB_G0283337 isoform X2 K23317 MTF1; metal regulatory transcription factor 1
D 102656661 uncharacterized protein LOC102656661 isoform X2 K24146 BNC; zinc finger protein basonuclin
D 725301 zinc finger protein 888 K09191 GTF3A; general transcription factor IIIA
D 100578927 transcriptional repressor protein YY1 isoform X2 K09201 YY; transcription factor YY
D 725934 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
D 410328 zinc finger protein 341 K24852 ZNF341; zinc finger protein 341
D 408455 zinc finger protein rotund isoform X1 K23480 ZNF362_384; zinc finger protein 362/384
D 413466 zinc finger protein 423 isoform X1 K22870 ZNF423; zinc finger protein 423
D 724604 LOW QUALITY PROTEIN: uncharacterized protein LOC724604 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100578559 zinc finger protein 724-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 102655124 zinc finger protein 135 K09228 KRAB; KRAB domain-containing zinc finger protein
D 409573 zinc finger protein 260 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 411780 zinc finger protein 578 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100577756 zinc finger protein 678 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100576600 zinc finger protein 345 K09228 KRAB; KRAB domain-containing zinc finger protein
D 102654736 zinc finger protein 239 K09228 KRAB; KRAB domain-containing zinc finger protein
D 409470 zinc finger protein 665 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100578482 zinc finger protein 629-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 100578924 zinc finger protein 271 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100576817 zinc finger and BTB domain-containing protein 41 K09228 KRAB; KRAB domain-containing zinc finger protein
D 724513 zinc finger protein 816 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100578529 zinc finger protein 701 K09228 KRAB; KRAB domain-containing zinc finger protein
D 102656501 zinc finger protein 2 K09228 KRAB; KRAB domain-containing zinc finger protein
D 413766 zinc finger protein 2 homolog isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100578355 zinc finger protein 484 K09228 KRAB; KRAB domain-containing zinc finger protein
D 102654395 zinc finger protein 184 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100578743 zinc finger protein 135 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 726368 zinc finger protein 883 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100578694 zinc finger protein 3 K09228 KRAB; KRAB domain-containing zinc finger protein
D 113218554 zinc finger protein 708-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 411930 uncharacterized protein LOC411930 K09228 KRAB; KRAB domain-containing zinc finger protein
D 113218788 zinc finger protein 567-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 724739 zinc finger protein 571-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 409153 zinc finger protein 423-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 100576131 zinc finger protein 267 K09228 KRAB; KRAB domain-containing zinc finger protein
D 102653601 zinc finger protein 85 K09228 KRAB; KRAB domain-containing zinc finger protein
D 411960 zinc finger protein 184 isoform X2 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100577250 zinc finger protein 845 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100576261 zinc finger protein 569 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100577696 fez family zinc finger protein erm-like K24502 FEZF; Fez family zinc finger protein
D 725754 uncharacterized protein LOC725754 isoform X2 K25209 CASZ1; zinc finger protein castor
D 725303 histone H4 transcription factor isoform X1 K25794 HINFP; histone H4 transcription factor
D 551803 homeotic protein spalt-major isoform X1 K19871 SALL; sal-like protein
D 100577561 uncharacterized protein LOC100577561 K27895 ATMIN; ATM interactor
D 411166 Kr; protein krueppel K09231 KR; krueppel
D 410326 Krueppel-like factor 10 K13943 CBT; cabut
D 410209 Hb; protein hunchback K09213 HB; hunchback
D 100578523 protein glass K09214 GL; glass
D 724961 protein drumstick isoform X2 K22535 DRM; drumstick
C Cys2HisCys zinc factors
D 100577801 zinc finger protein ush isoform X5 K17441 ZFPM1; zinc finger protein ZFPM1
D 552696 histone acetyltransferase KAT8 isoform X2 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D 408793 histone acetyltransferase KAT7 isoform X1 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
D 724159 histone acetyltransferase KAT6B isoform X1 K11306 MYST4; histone acetyltransferase MYST4 [EC:2.3.1.48]
D 413101 histone acetyltransferase Tip60 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D 408319 lethal(3)malignant brain tumor-like protein 3 isoform X1 K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
D 551406 cell growth-regulating nucleolar protein K15263 LYER; cell growth-regulating nucleolar protein
C Cys3His zinc factors
D 552497 uncharacterized protein LOC552497 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 409200 uncharacterized protein DDB_G0289975 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
C Cys2CysHis zinc factors
D 102655420 uncharacterized protein LOC102655420 K23203 THAP1_3; THAP domain-containing protein 1/3
C CXXC CpG-binding proteins
D 408716 histone-lysine N-methyltransferase trithorax isoform X1 K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
D 411265 CXXC-type zinc finger protein 1 K14960 CXXC1; COMPASS component SPP1
D 412878 DNA N6-methyl adenine demethylase isoform X1 K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
D 726540 DNA (cytosine-5)-methyltransferase PliMCI K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 100328599 Dnmt1a; DNA methyltransferase 1a K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 410848 jmjC domain-containing histone demethylation protein 1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
D 413288 polycomb protein Pcl isoform X1 K11485 MTF2; metal regulatory transcription factor 2
D 412455 protein shuttle craft K12236 NFX1; transcriptional repressor NF-X1
D 725076 CCHC-type zinc finger protein CG3800 K09250 CNBP; cellular nucleic acid-binding protein
D 412302 zinc finger C4H2 domain-containing protein isoform X1 K24369 ZC4H2; zinc finger C4H2 domain-contaning protein
D 409876 interferon regulatory factor 2-binding protein-like B K22383 IRF2BP; interferon regulatory factor 2-binding protein
B Helix-turn-helix
C Homeo domain ANTP: HOXL
D 724422 homeobox protein Hox-B1a isoform X2 K09301 HOX_1; homeobox protein HoxA/B/D1
D 410648 homeotic protein proboscipedia K09302 HOX_2; homeobox protein HoxA/B2
D 724252 homeotic protein deformed K09304 HOX_4; homeobox protein HoxA/B/C/D4
D 551506 homeobox protein H55 K09305 HOX_5; homeobox protein HoxA/B/C5
D 410643 homeobox protein abdominal-A homolog isoform X1 K09307 HOX_7; homeobox protein HoxA/B7
D 551594 Ubx; ultrabithorax K09307 HOX_7; homeobox protein HoxA/B7
D 406077 Antp; homeobox protein H90 K09307 HOX_7; homeobox protein HoxA/B7
D 725058 GS homeobox 1 K09310 GSH; homeobox protein GSH
D 726676 cad; homeotic protein caudal K09312 CDX1_4; homeobox protein CDX1/4
D 724845 eve; segmentation protein even-skipped K09320 EVX; homeobox even-skipped homolog protein
D 725495 homeobox protein GBX-2 K09321 GBX; homeobox protein GBX
D 725407 homeobox protein Hox-C6a isoform X1 K09322 MEOX; homeobox protein MOX
D 410642 homeobox protein abdominal-B isoform X1 K09300 ABDB; homeobox protein abdominal-B and related proteins
C Homeo domain ANTP: NKL
D 725504 homeobox protein ARX K09309 NKX1; homeobox protein Nkx-1
D 411104 homeobox protein Nkx-2.4 K09342 NKX2-1; homeobox protein Nkx-2.1
D 725671 homeobox protein Nkx-2.8 isoform X1 K08029 NKX2-2; homeobox protein Nkx-2.2
D 100577942 homeobox protein Nkx-2.5-like K09995 NKX3-2; homeobox protein Nkx-3.2
D 102656029 homeobox protein Hmx K09349 NKX5; homeobox protein Nkx-5
D 725220 homeobox protein Nkx-6.1 K08030 NKX6-1; homeobox protein Nkx-6.1
D 726710 Dll; distal-less K18488 DLX2; homeobox protein DLX2
D 724148 homeobox protein MSX-2 K15607 TLX3; T-cell leukemia homeobox protein 3
D 725302 H2.0-like homeobox protein K09339 HLX1; homeobox protein HLX1
D 552099 homeotic protein empty spiracles K09317 EMX; homeobox protein EMX
D 725151 homeobox protein E30 K09319 EN; homeobox protein engrailed
D 100577365 homeobox protein invected isoform X2 K09319 EN; homeobox protein engrailed
D 724412 muscle segmentation homeobox K09341 MSX; homeobox protein MSX
D 724456 Msx; homeobox protein H17 K09341 MSX; homeobox protein MSX
D 107965480 homeobox protein engrailed-2-B K09341 MSX; homeobox protein MSX
D 725590 homeobox protein B-H2-like K09360 BARHL; BarH-like
D 724801 brain-specific homeobox protein homolog K24874 BSX; brain-specific homeobox protein
D 102655824 uncharacterized protein LOC102655824 K24875 DBX; homeobox protein DBX
C Homeo domain Paired-related
D 552251 homeobox protein aristaless K09452 ARX; homeobox protein aristaless-related
D 725502 homeobox protein ARX K09452 ARX; homeobox protein aristaless-related
D 726162 homeobox protein goosecoid K09324 GSC; homeobox protein goosecoid
D 410684 homeobox protein OTX1 A isoform X1 K09326 OTX1; homeobox protein OTX1
D 551357 otd2; uncharacterized protein LOC551357 K18490 OTX2; homeobox protein OTX2
D 726538 homeobox protein prophet of Pit-1 K09327 PROP1; homeobox protein prophet of Pit-1
D 408443 uncharacterized protein LOC408443 K09328 UNC4; homeobox protein Unc-4
D 724301 paired mesoderm homeobox protein 2-like isoform X2 K09329 PRRX; paired mesoderm homeobox protein
D 724934 paired mesoderm homeobox protein 2A K09330 PHOX2; paired mesoderm homeobox protein 2
D 724307 paired mesoderm homeobox protein 2-like K09331 SHOX; short stature homeobox protein
D 724196 retinal homeobox protein Rx1 K09332 RAX; retina and anterior neural fold homeobox protein
D 411315 visual system homeobox 2 isoform X1 K09336 VSX2; visual system homeobox protein 2
D 724120 paired mesoderm homeobox protein 2B K24895 DRGX; dorsal root ganglia homeobox protein
D 726978 homeodomain-only protein K24897 HOPX; homeodomain-only protein
D 724282 homeobox protein orthopedia K24901 OTP; homeobox protein orthopedia
D 726200 paired box protein Pax-1 isoform X1 K09382 PAX1_9; paired box protein 1/9
D 726761 insulin receptor substrate 4 isoform X1 K15608 PAX2; paired box protein 2
D 727035 paired box pox-neuro protein K15608 PAX2; paired box protein 2
D 411374 protein gooseberry-neuro-like K09381 PAX3_7; paired box protein 3/7
D 411373 protein gooseberry isoform X1 K09381 PAX3_7; paired box protein 3/7
D 410499 protein gooseberry K09381 PAX3_7; paired box protein 3/7
D 724238 paired box protein Pax-6 isoform X2 K08031 PAX6; paired box protein 6
D 102654776 paired box protein Pax-6 isoform X1 K08031 PAX6; paired box protein 6
D 410818 Eyg; eyegone K08031 PAX6; paired box protein 6
C Homeo domain LIM
D 100577472 insulin gene enhancer protein ISL-1 isoform X1 K09370 ISL1; insulin gene enhancer protein ISL-1
D 724778 LIM homeobox transcription factor 1-beta isoform X1 K09371 LMX1; LIM homeobox transcription factor 1
D 100577751 LIM/homeobox protein Lhx5 isoform X1 K09372 LHX1; LIM homeobox protein 1
D 409095 LIM domain-containing protein A isoform X1 K09373 LHX2_9; LIM homeobox protein 2/9
D 726415 LIM/homeobox protein Lhx9 K09373 LHX2_9; LIM homeobox protein 2/9
D 410658 LIM/homeobox protein Lhx3 isoform X2 K09374 LHX3_4; LIM homeobox protein 3/4
D 411285 muscle LIM protein Mlp84B isoform X1 K09377 CSRP; cysteine and glycine-rich protein
C Homeo domain POU
D 727092 POU domain, class 2, transcription factor 1 isoform X1 K09364 POU2F; POU domain transcription factor, class 2
D 100577603 POU domain protein CF1A K09365 POU3F; POU domain transcription factor, class 3
D 410657 inhibitory POU protein isoform X1 K09366 POU4F; POU domain transcription factor, class 4
D 408435 POU domain, class 6, transcription factor 1 isoform X1 K09368 POU6F; POU domain transcription factor, class 6
C Homeo domain SINE
D 413366 homeobox protein SIX2 isoform X1 K15614 SIX1; homeobox protein SIX1
D 551364 homeobox protein SIX3 K19473 SIX3_6; homeobox protein SIX3/6
D 724796 homeobox protein SIX6 K15615 SIX4; homeobox protein SIX4
C Homeo domain ZF
D 410304 zinc finger homeobox protein 4 isoform X2 K09378 ZFHX3; zinc finger homeobox protein 3
D 100576993 zinc finger protein 1 isoform X1 K23560 ZEB2; zinc finger homeobox protein 2
C Homeo domain CUT
D 551460 homeobox protein cut isoform X9 K09313 CUTL; homeobox protein cut-like
D 552619 homeobox protein onecut K08026 ONECUT1; one cut domain, family member 1 (hepatocyte nuclear factor 6)
C Homeo domain PROS
D 406073 homeobox protein prospero isoform X1 K20211 PROX1; prospero homeobox 1
C Homeo domain TALE
D 408763 homeobox protein extradenticle isoform X1 K09355 PBX1; pre-B-cell leukemia transcription factor 1
D 726999 iroquois-class homeodomain protein IRX-6 isoform X2 K19383 TGIF1; homeobox protein TGIF1
D 412840 homeobox protein caupolican isoform X2 K24889 IRX; iroquois-class homeodomain protein IRX
D 412839 iroquois-class homeodomain protein IRX-6 isoform X1 K24889 IRX; iroquois-class homeodomain protein IRX
D 724727 homeobox protein PKNOX2 isoform X1 K24891 PKNOX; homeobox protein PKNOX
D 552079 homeobox protein homothorax isoform X1 K16672 HTH; homeobox protein homothorax
C Homeo domain other
D 100578718 protein distal antenna K22536 DAN; distal antenna
D 100576220 homeobox protein rough-like K09362 K09362; homeo domain only family, other
C Fork head/winged helix developmental regulators
D 411296 silk gland factor 1 K08035 FOXA2; forkhead box protein A2, hepatocyte nuclear factor 3-beta
D 725966 fork head domain-containing protein crocodile K09396 FOXC; forkhead box protein C
D 724740 fork head domain transcription factor slp2 K09385 FOXG; forkhead box protein G
D 552820 forkhead box protein N3 K09407 FOXN; forkhead box protein N
D 411276 hybrid signal transduction histidine kinase D isoform X1 K09407 FOXN; forkhead box protein N
C Fork head/winged helix tissue-specific regulators
D 100576194 forkhead box protein J1 K09402 FOXJ1; forkhead box protein J1
C Fork head/winged helix cell cycle-controlling factors, E2F
D 412770 transcription factor E2F2 K09389 E2F2; transcription factor E2F2
D 551896 transcription factor E2F4 K04682 E2F4_5; transcription factor E2F4/5
C Fork head/winged helix cell cycle-controlling factors, DP
D 409887 transcription factor Dp-1 K04683 TFDP1; transcription factor Dp-1
C Fork head/winged helix other regulators
D 724315 forkhead box protein D3 K09397 FOXD; forkhead box protein D
D 726050 forkhead box protein K2 K09399 FOXF; forkhead box protein F
D 551340 forkhead box protein K1 isoform X1 K09404 FOXK; forkhead box protein K
D 726165 fork head domain transcription factor slp1 isoform X1 K09405 FOXL; forkhead box protein L
D 727091 forkhead box protein O isoform X2 K09408 FOXO3; forkhead box protein O3
D 408423 Foxp; FoxP protein K09409 FOXP2_4; forkhead box protein P2/4
D 726400 forkhead box protein I1-ema K09411 FOXX; forkhead box protein, other
D 724979 forkhead box protein A2-A-like K09411 FOXX; forkhead box protein, other
C Heat shock factors
D 411854 heat shock factor protein isoform X4 K09414 HSF1; heat shock transcription factor 1
C Tryptophan clusters Myb, Myb-factors
D 409733 myb protein isoform X2 K09420 MYB; transcriptional activator Myb
C Tryptophan clusters Myb, Myb-like factors
C Tryptophan clusters Ets-type
D 408758 E74; ecdysteroid-regulated gene E74 K09428 ELF1_2_4; E74-like factor 1/2/4
D 552797 ETS-related transcription factor Elf-5 K17102 EHF; ETS homologous factor
D 726458 ETS-like protein pointed K15593 ETV5; ets translocation variant 5
D 100576369 ets DNA-binding protein pokkuri isoform X1 K03211 ETV6_7; ETS translocation variant 6/7
D 412916 ETS-like protein pointed isoform X1 K02678 ETS1; C-ets-1
D 551804 DNA-binding protein D-ETS-3 isoform X1 K09436 FLI1; friend leukemia integration 1 transcription factor
D 100578252 Ets97D-like; DNA-binding protein Ets97D homolog K09441 GABPA; GA-binding protein transcription factor, alpha
D 413060 DNA-binding protein D-ETS-4 isoform X2 K09442 SPDEF; SAM pointed domain-containing ETS transcription factor
D 725629 DNA-binding protein D-ETS-6-like K09443 K09443; ETS-type family, other
C Tryptophan clusters interferon-regulating factors
C TEA domain
D 408616 transcriptional enhancer factor TEF-1 isoform X2 K09448 TEAD; transcriptional enhancer factor
C ARID
D 412046 trithorax group protein osa isoform X1 K11653 ARID1; AT-rich interactive domain-containing protein 1
D 724311 AT-rich interactive domain-containing protein 2 isoform X1 K11765 ARID2; AT-rich interactive domain-containing protein 2
D 725697 protein dead ringer isoform X1 K25856 ARID3; AT-rich interactive domain-containing protein 3
D 409456 AT-rich interactive domain-containing protein 4B isoform X1 K19195 ARID4B; AT-rich interactive domain-containing protein 4B
D 100576405 protein split ends isoform X1 K25857 ARID5; AT-rich interactive domain-containing protein 5
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
D 552247 nuclear factor NF-kappa-B p100 subunit isoform X1 K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
D 411712 embryonic polarity protein dorsal isoform X2 K09254 REL; c-Rel proto-oncogene protein
D 406086 Dl; dorsal protein isoform A K09254 REL; c-Rel proto-oncogene protein
C RHR (Rel homology region) Ankyrin only
D 411012 NF-kappa-B inhibitor cactus K04734 NFKBIA; NF-kappa-B inhibitor alpha
D 725124 cact1; NF-kappa-B inhibitor cactus 1 K04734 NFKBIA; NF-kappa-B inhibitor alpha
D 724663 tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
D 412357 GA-binding protein subunit beta-1 isoform X1 K09454 GABPB; GA-binding protein transcription factor, beta
C RHR (Rel homology region) NF-AT
D 408354 nuclear factor of activated T-cells 5 isoform X4 K17335 NFAT5; nuclear factor of activated T-cells 5
C STAT
D 413742 signal transducer and activator of transcription 5B K11224 STAT5B; signal transducer and activator of transcription 5B
C p53
C MADS-box regulators of differentiation, MEF-2
D 413946 myocyte-specific enhancer factor 2 isoform X1 K09260 MEF2A; MADS-box transcription enhancer factor 2A
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
D 724322 serum response factor homolog isoform X1 K04378 SRF; serum response factor
C SAND domain-containing proteins
D 412296 deformed epidermal autoregulatory factor 1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
C TATA-binding proteins
D 410753 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 550692 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 412919 TATA box-binding protein-like protein 1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
C HMG SOX
D 726150 transcription factor Sox-21-B K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 102653993 transcription factor Sox-21-B-like K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 726180 transcription factor Sox-19b-like isoform X3 K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 408411 transcription factor Sox-2 isoform X1 K16796 SOX2; transcription factor SOX2 (SOX group B)
D 726914 probable serine/threonine-protein kinase DDB_G0272282 K23581 SOX4; transcription factor SOX4 (SOX group C)
D 408884 transcription factor SOX-5 isoform X2 K09269 SOX5_6_13; transcription factor SOX5/6/13 (SOX group D)
D 727287 transcription factor Sox-7 K09270 SOX7S; transcription factor SOX7/8/10/18 (SOX group E/F)
D 726298 putative transcription factor SOX-15 isoform X1 K09270 SOX7S; transcription factor SOX7/8/10/18 (SOX group E/F)
D 727284 transcription factor Sox-10 isoform X2 K18435 SOX9; transcription factor SOX9 (SOX group E)
D 100578885 putative transcription factor capicua isoform X1 K20225 CIC; capicua transcriptional repressor
D 551787 HMG box transcription factor BBX isoform X1 K21643 BBX; HMG box transcription factor BBX
C HMG TCF-1
D 726671 uncharacterized protein LOC726671 isoform X1 K04491 TCF7L2; transcription factor 7-like 2
C HMG2-related
D 726058 FACT complex subunit Ssrp1 K09272 SSRP1; FACT complex subunit SSRP1/POB3
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
D 725757 nuclear transcription factor Y subunit alpha isoform X1 K08064 NFYA; nuclear transcription factor Y, alpha
D 411193 nuclear transcription factor Y subunit B-1 isoform X2 K08065 NFYB; nuclear transcription Y subunit beta
D 408615 nuclear transcription factor Y subunit gamma K08066 NFYC; nuclear transcription factor Y, gamma
C Grainyhead
D 725290 transcription factor CP2-like protein 1 isoform X1 K09275 TFCP2; transcription factor CP2 and related proteins
D 411079 protein grainyhead isoform X1 K09275 TFCP2; transcription factor CP2 and related proteins
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
D 409854 Y-box factor homolog isoform X2 K09276 YBX1; Y-box-binding protein 1
C Cold-shock domain factors, FRG Y2-like
C Runt
D 726124 segmentation protein Runt K20213 RUN; RUNX transcription factor Runt
D 410537 protein lozenge K20214 LZ; RUNX transcription factor Lozenge
D 410534 uncharacterized protein LOC410534 K09280 RUNXA_B; runt-related transcription factor
D 410535 runt-related transcription factor 1 isoform X1 K09280 RUNXA_B; runt-related transcription factor
C MYRF
D 410166 myelin regulatory factor-like protein isoform X3 K24768 MYRF; myelin regulatory factor [EC:3.4.-.-]
B Other transcription factors
C HMGI(Y)
D 100577909 high mobility group protein I K09282 HMGA1; high mobility group AT-hook protein 1
C NUPR
D 726175 nuclear protein 1 K15626 NUPR1; nuclear protein 1
E Line #4
C Pocket domain Rb
D 411627 retinoblastoma-like protein 1 isoform X2 K04681 RBL1; retinoblastoma-like protein 1
C Pocket domain CBP
D 726280 histone acetyltransferase p300-like isoform X3 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C T-box
D 412976 brachyury protein K10172 BRA; brachyury protein
D 552311 T-box transcription factor TBX10 isoform X1 K10175 TBX1; T-box protein 1
D 726842 optomotor-blind protein isoform X1 K10176 TBX2; T-box protein 2
D 410885 T-box protein 2 K10180 TBX6; T-box protein 6
D 726654 T-box protein H15 isoform X1 K10185 TBX20; T-box protein 20
D 411133 T-box transcription factor TBX20 isoform X1 K10185 TBX20; T-box protein 20
C DMRT
D 100577410 uncharacterized protein LOC100577410 K19489 DMRT2; doublesex- and mab-3-related transcription factor 2
D 726743 doublesex- and mab-3-related transcription factor A2 K19491 DMRT4_5; doublesex- and mab-3-related transcription factor 4/5
C LRRFIP
D 413006 leucine-rich repeat flightless-interacting protein 2 isoform X1 K26434 LRRFIP; leucine-rich repeat flightless-interacting protein
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
D 724592 calmodulin-binding transcription activator 2 isoform X1 K21596 CAMTA; calmodulin-binding transcription activator
D 410334 uncharacterized protein LOC410334 isoform X2 K21598 GCM; chorion-specific transcription factor GCM
D 552460 transmembrane protein 18 K22145 TMEM18; transmembrane protein 18
D 408308 coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2
D 413870 suppressor of hairless protein K06053 RBPSUH; recombining binding protein suppressor of hairless
D 552185 GON-4-like protein K23804 GON4L; GON-4-like protein
D 726399 transcriptional activator protein Pur-beta isoform X1 K21772 PURA; transcriptional activator protein Pur-alpha
D 411969 heterogeneous nuclear ribonucleoprotein M isoform X1 K24992 MYEF2; myelin expression factor 2
D 725859 cell division cycle-associated protein 7 K23408 CDCA7; cell division cycle-associated protein 7
D 411861 NF-kappa-B-repressing factor K26458 NKRF; NF-kappa-B-repressing factor
#
AProkaryotic type
B Helix-turn-helix
C AraC family
C LysR family
C DeoR family
C LacI family
C GntR family
C TetR/AcrR family
C Lrp/AsnC family
C LuxR family
C MarR family
C MerR family
C Fur family
C IclR family
C CRP/FNR family
C Rrf2 family
C ArsR family
C XRE family
C PadR family
C Other families
B Ribbon-helix-helix
C CopG family
C Other families
B Other transcription factors
C BglG family
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 7, 2024
#
Classification taken and modified from TRANSFAC 7.0