+D GENES KO
#
KEGG Orthology (KO) - Aeropyrum pernix
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:ape00010]
D APE_2091.1 ATP-dependent glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D APE_0768.1 bifunctional phosphoglucose / phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D APE_0011.1 fba; fructose-bisphosphate aldolase class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APE_1109.1 fbpA; fructose-1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D APE_1538.1 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D APE_0171.1 glyceraldehyde 3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D APE_0173.1 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D APE_1616.1 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D APE_2458 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APE_0489 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D APE_0650.1 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D APE_1677.1 pdhA; pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APE_1674 pdhB; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APE_1671 pdhC; pyruvate dehydrogenase complex, E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_1473.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_2126.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_1472 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_2128 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_1346.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604a.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_1786.1 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90]
D APE_0033.1 pckA; phosphoenolpyruvate carboxykinase [ATP] K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C 00020 Citrate cycle (TCA cycle) [PATH:ape00020]
D APE_1713 gltA; citrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D APE_1618.1 citB; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D APE_0689.1 isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_1473.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_2126.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_1472 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_2128 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_1072.1 sucD; succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D APE_1065.1 sucC; succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APE_0950.1 sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APE_0946 sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APE_0948.1 sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APE_0947 sdhD; putative succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D APE_1816.1 fumC; fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D APE_0672.1 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APE_0033.1 pckA; phosphoenolpyruvate carboxykinase [ATP] K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D APE_1677.1 pdhA; pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APE_1674 pdhB; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APE_1671 pdhC; pyruvate dehydrogenase complex, E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:ape00030]
D APE_0768.1 bifunctional phosphoglucose / phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D APE_0583 putative transketolase C-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APE_0586.1 putative transketolase N-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APE_0665 rpiA; ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D APE_0952.1 hxlA; hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D APE_1940.1 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D APE_2437.1 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D APE_2106.1 ATP-dependent 6-phosphofructokinase K00852 rbsK; ribokinase [EC:2.7.1.15]
D APE_2433.1 phospho-sugar mutase K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_0012 ATP-dependent 6-phosphofructokinase K26208 E2.7.1.239; alpha-D-ribose-1-phosphate 5-kinase (ATP) [EC:2.7.1.239]
D APE_1834.1 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D APE_1786.1 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90]
D APE_0266.1 aor; tungsten-containing aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D APE_0996.1 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D APE_0011.1 fba; fructose-bisphosphate aldolase class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APE_1109.1 fbpA; fructose-1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
C 00040 Pentose and glucuronate interconversions [PATH:ape00040]
D APE_0017.1 carbohydrate kinase, FGGY family K00854 xylB; xylulokinase [EC:2.7.1.17]
D APE_1657.1 aldolase class II protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
C 00051 Fructose and mannose metabolism [PATH:ape00051]
D APE_0768.1 bifunctional phosphoglucose / phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_0255.1 putative sugar-phosphate nucleotidyl transferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D APE_1657.1 aldolase class II protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
D APE_0889.1 mpgs; mannosyl-3-phosphoglycerate synthase K05947 E2.4.1.217; mannosyl-3-phosphoglycerate synthase [EC:2.4.1.217]
D APE_0887.1 mannosyl-3-phosphoglycerate phosphatase K07026 E3.1.3.70; mannosyl-3-phosphoglycerate phosphatase [EC:3.1.3.70]
D APE_0011.1 fba; fructose-bisphosphate aldolase class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APE_1109.1 fbpA; fructose-1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D APE_1538.1 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:ape00052]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_2091.1 ATP-dependent glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism [PATH:ape00500]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_2091.1 ATP-dependent glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D APE_0768.1 bifunctional phosphoglucose / phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:ape00520]
D APE_1205.1 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D APE_1202.1 putative nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D APE_2091.1 ATP-dependent glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_0768.1 bifunctional phosphoglucose / phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D APE_0255.1 putative sugar-phosphate nucleotidyl transferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
C 00541 Biosynthesis of various nucleotide sugars [PATH:ape00541]
D APE_1181 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1208.1 putative nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_2291 putative sugar-phosphate nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1180 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D APE_1178 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D APE_1179.1 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00620 Pyruvate metabolism [PATH:ape00620]
D APE_1346.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604a.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_1473.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_2126.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_1472 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_2128 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_1677.1 pdhA; pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APE_1674 pdhB; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APE_1671 pdhC; pyruvate dehydrogenase complex, E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0489 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D APE_1591.1 putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D APE_2468.1 putative propionate CoA-transferase K01026 pct; propionate CoA-transferase [EC:2.8.3.1]
D APE_0392 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D APE_0672.1 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APE_1816.1 fumC; fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D APE_0033.1 pckA; phosphoenolpyruvate carboxykinase [ATP] K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D APE_0650.1 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:ape00630]
D APE_1346.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604a.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_0672.1 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APE_1713 gltA; citrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D APE_1618.1 citB; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_1686.1 coenzyme B12-dependent mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D APE_1687 coenzyme B12-dependent mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D APE_0487 loxD; D-lactate dehydrogenase K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D APE_1831.1 gyaR; glyoxylate reductase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26]
D APE_0766 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D APE_2142.1 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APE_1962.1 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APE_2124.1 gcvPA; glycine cleavage system P-protein subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D APE_2121.1 gcvPB; glycine cleavage system P-protein subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D APE_1695.1 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0951.1 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D APE_0996.1 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D APE_0528 acetamidase/formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
C 00640 Propanoate metabolism [PATH:ape00640]
D APE_1346.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604a.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2468.1 putative propionate CoA-transferase K01026 pct; propionate CoA-transferase [EC:2.8.3.1]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0457 class-III aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D APE_1686.1 coenzyme B12-dependent mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D APE_1687 coenzyme B12-dependent mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D APE_1065.1 sucC; succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APE_1072.1 sucD; succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D APE_1713 gltA; citrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D APE_2147.1 prpD; 2-methylcitrate dehydratase K01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79]
D APE_1618.1 citB; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D APE_0222.1 putative carboxyvinyl-carboxyphosphonate phosphorylmutase K03417 prpB; methylisocitrate lyase [EC:4.1.3.30]
C 00650 Butanoate metabolism [PATH:ape00650]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2520.1 maiA; maleate cis-trans isomerase K01799 nicE; maleate isomerase [EC:5.2.1.1]
D APE_0950.1 sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APE_0946 sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APE_0948.1 sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APE_0947 sdhD; putative succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D APE_0457 class-III aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D APE_1473.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_2126.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_1472 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_2128 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_1873.1 putative hydroxymethylglutaryl-coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D APE_2239.1 adh; NAD-dependent alcohol dehydrogenase K18382 adh1; NAD+-dependent secondary alcohol dehydrogenase Adh1 [EC:1.1.1.-]
D APE_2509 putative acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:ape00660]
D APE_2509 putative acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D APE_1065.1 sucC; succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APE_1072.1 sucD; succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00562 Inositol phosphate metabolism [PATH:ape00562]
D APE_1798.1 fbpA; fructose-1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D APE_1517 ino1; inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D APE_1514.1 hypothetical protein K07281 ipct; 1L-myo-inositol 1-phosphate cytidylyltransferase [EC:2.7.7.74]
D APE_1516.1 putative CDP-alcohol phosphatidyltransferase K07291 dipps; CDP-L-myo-inositol myo-inositolphosphotransferase [EC:2.7.8.34]
D APE_1538.1 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:ape00190]
D APE_1430.1 NuoA homolog K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D APE_1428.1 NuoB homolog K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D APE_1426 NuoC homolog K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D APE_1422 NuoD homolog K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D APE_1421.1 NuoH homolog K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D APE_1419.1 NuoI homolog K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D APE_1418.1 NuoJ homolog K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D APE_1417.1 NuoK homolog K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D APE_1411.1 NuoL homolog K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D APE_1415 NuoM homolog K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D APE_1410.1 NuoN homolog K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D APE_0950.1 sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APE_0946 sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APE_0948.1 sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APE_0947 sdhD; putative succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D APE_1878 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D APE_0795.1 aoxC; cytochrome c oxidase (aa3-type) subunit IV K02277 coxD; cytochrome c oxidase subunit IV [EC:7.1.1.9]
D APE_1623 cytochrome c oxidase (ba3-type) subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D APE_0793.1 aoxB; cytochrome c oxidase (aa3-type) subunit I+III K15408 coxAC; cytochrome c oxidase subunit I+III [EC:7.1.1.9]
D APE_0792.1 aoxA; cytochrome c oxidase (aa3-type) subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D APE_1720 cytochrome c oxidase (ba3-type) subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D APE_1694.1 cytochrome AA3 controlling protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D APE_0405.1 atpA; V-type ATP synthase subunits A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D APE_0404.1 aptB; V-type ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D APE_0402.1 atpD; V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D APE_0409.1 atpE; V-type ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D APE_0410.1 atpF; putative V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D APE_0673.1 atpI; V-type ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D APE_2326.1 atpP; V-type ATP synthase subunit L K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D APE_1692.1 inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:ape00710]
D APE_0173.1 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D APE_0171.1 glyceraldehyde 3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D APE_0011.1 fba; fructose-bisphosphate aldolase class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APE_0583 putative transketolase C-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APE_0586.1 putative transketolase N-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APE_0665 rpiA; ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D APE_1538.1 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D APE_0033.1 pckA; phosphoenolpyruvate carboxykinase [ATP] K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D APE_0672.1 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:ape00720]
D APE_0650.1 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D APE_0672.1 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APE_1816.1 fumC; fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D APE_0950.1 sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APE_0946 sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APE_0948.1 sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APE_0947 sdhD; putative succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D APE_1072.1 sucD; succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D APE_1065.1 sucC; succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APE_1484.1 3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA dehydratase K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_1473.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_2126.1 2-oxoacid:ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D APE_1472 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_2128 2-oxoacid:ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D APE_0689.1 isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D APE_1618.1 citB; aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D APE_1687 coenzyme B12-dependent mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D APE_1686.1 coenzyme B12-dependent mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D APE_1346.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604a.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:ape00680]
D APE_1962.1 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APE_0996.1 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D APE_2458 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APE_0672.1 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APE_0011.1 fba; fructose-bisphosphate aldolase class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APE_1109.1 fbpA; fructose-1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D APE_1940.1 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D APE_0952.1 hxlA; hexulose-6-phosphate synthase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D APE_1346.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604a.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_0650.1 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D APE_1616.1 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D APE_0683 phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D APE_0412 hypothetical protein K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00910 Nitrogen metabolism [PATH:ape00910]
D APE_0528 acetamidase/formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
D APE_1288.1 narG; nitrate reductase, alpha subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D APE_1294.1 narH; nitrate reductase, beta subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D APE_1386.1 NADP-dependent glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D APE_2142.1 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APE_0935 hypothetical protein K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D APE_1968 carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00920 Sulfur metabolism [PATH:ape00920]
D APE_1197.1 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D APE_1195.1 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]
D APE_0595.1 putative dehydrogenase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D APE_1043.1 putative dehydrogenase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D APE_2595.1 thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D APE_1586 cysK; cysteine synthase K10150 cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
D APE_2068 metB; cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:ape00061]
D APE_0912 putative dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APE_2503.1 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APE_1307 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_1310 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_2284.1 fadD; long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:ape00071]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_1872.1 putative 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D APE_1307 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_1310 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_2284.1 fadD; long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:ape00561]
D APE_0996.1 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D APE_0306.1 putative carbohydrate kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
C 00564 Glycerophospholipid metabolism [PATH:ape00564]
D APE_0309.1 putative oxidoreductase K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D APE_0262 hypothetical protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D APE_0519.1 glycerol-1-phosphate dehydrogenase [NAD(P)] K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D APE_0433 conserved hypothetical protein K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
C 00565 Ether lipid metabolism
D APE_0308.1 eapA; alkyldihydroxyacetonephosphate synthase K00803 AGPS; alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]
C 00600 Sphingolipid metabolism [PATH:ape00600]
D APE_0020.1 putative pyridoxal-dependent decarboxylase K01634 SGPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
D APE_2267.1 putative pyridoxal-dependent decarboxylase K01634 SGPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism [PATH:ape00592]
D APE_1872.1 putative 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:ape00230]
D APE_1481.1 nudF; ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D APE_2080.1 nudF; ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D APE_2433.1 phospho-sugar mutase K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_1834.1 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D APE_0801.1 surE; 5'(3')-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D APE_1507.1 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D APE_2377 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D APE_0788.1 conserved hypothetical protein K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73]
D APE_1138.1 ntpA; nucleoside-triphosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D APE_2452 guaA; GMP synthase [glutamine-hydrolyzing] K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D APE_2062.1 ribonucleotide reductase, B12-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APE_1761.1 conserved hypothetical protein K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D APE_0981.1 adkA; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D APE_2094.1 conserved hypothetical protein K18532 AK6; adenylate kinase [EC:2.7.4.3]
D APE_0781.1 conserved hypothetical protein K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
D APE_0122.1 conserved hypothetical protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D APE_1195.1 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]
D APE_1197.1 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D APE_1968 carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00240 Pyrimidine metabolism [PATH:ape00240]
D APE_1663.1 pyrB; aspartate carbamoyltransferase, catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D APE_1662.1 pyrI; aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D APE_0261.1 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D APE_0260.1 pyrD; probable dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
D APE_2349.1 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D APE_2348 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D APE_0401.1 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D APE_2377 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D APE_1604 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D APE_0978.1 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D APE_0801.1 surE; 5'(3')-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D APE_2105.1 udp; uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3]
D APE_0545.1 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D APE_1038.1 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D APE_0333.1 dut; dUTP diphosphatase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D APE_2062.1 ribonucleotide reductase, B12-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APE_2090 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D APE_0069.1 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D APE_2064.1 thyX; thymidylate synthase ThyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:ape00250]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2041.1 putative asparagine synthetase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D APE_1663.1 pyrB; aspartate carbamoyltransferase, catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D APE_1662.1 pyrI; aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D APE_0457 class-III aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D APE_0935 hypothetical protein K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D APE_1386.1 NADP-dependent glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D APE_0807.1 delta-1-pyrroline-5-carboxylate dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D APE_2142.1 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APE_1205.1 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C 00260 Glycine, serine and threonine metabolism [PATH:ape00260]
D APE_1140.1 lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D APE_1143 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D APE_1144.1 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D APE_2067.1 thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D APE_1488.1 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D APE_2286 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D APE_1962.1 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APE_0996.1 glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D APE_1616.1 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D APE_0683 phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D APE_2124.1 gcvPA; glycine cleavage system P-protein subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D APE_2121.1 gcvPB; glycine cleavage system P-protein subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D APE_1695.1 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0951.1 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D APE_1223.1 cystathionine beta-synthase K01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]
D APE_1586 cysK; cysteine synthase K10150 cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
D APE_1226 metC; cystathionine gamma-lyase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D APE_1498.1 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D APE_2550 trpA; tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D APE_2548 trpB; tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D APE_2316 trpB; tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:ape00270]
D APE_1586 cysK; cysteine synthase K10150 cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
D APE_1226 metC; cystathionine gamma-lyase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D APE_1223.1 cystathionine beta-synthase K01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]
D APE_2048 metE; methylcobalamin:homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D APE_2050.1 putative methylcobalamin:homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D APE_1596 mat; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D APE_0079 speH; S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D APE_0639.1 speH; S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D APE_0767.1 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D APE_0993.1 mtaP; S-methyl-5-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
D APE_1885 5'-methylthioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
D APE_0686 mtnA; putative methylthioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D APE_0872.1 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_2002 cytosine-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_0624.1 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D APE_1140.1 lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D APE_1143 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D APE_1144.1 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D APE_2067.1 thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D APE_2068 metB; cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2595.1 thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D APE_0672.1 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00280 Valine, leucine and isoleucine degradation [PATH:ape00280]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_1872.1 putative 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D APE_1686.1 coenzyme B12-dependent mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D APE_1687 coenzyme B12-dependent mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D APE_0756.1 putative dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_1873.1 putative hydroxymethylglutaryl-coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:ape00290]
D APE_1498.1 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D APE_2509 putative acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D APE_0013.1 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
C 00300 Lysine biosynthesis [PATH:ape00300]
D APE_1144.1 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D APE_1140.1 lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D APE_1143 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D APE_1023.1 dapA; putative dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D APE_0632.1 conserved hypothetical protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D APE_1917 hypothetical protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D APE_0169.1 agt; alanine glyoxylate transaminase K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]
D APE_1462a lysW; lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D APE_1463 lysX; lysine biosynthesis protein LysX/ribosomal protein S6 modification protein RimK K05827 lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
D APE_1461.1 lysZ; acetylaminoadipate kinase/acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D APE_1462 lysY; N-acetyl-gamma-aminoadipyl-phosphate reductase/N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D APE_1464 lysJ; acetyl-lysine aminotransferase/acetylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D APE_1467.1 lysK; acetyl-lysine deacetylase/acetylornithine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00310 Lysine degradation [PATH:ape00310]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00220 Arginine biosynthesis [PATH:ape00220]
D APE_1992.1 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D APE_2142.1 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APE_1968 carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
D APE_1386.1 NADP-dependent glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_1462a lysW; lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D APE_1461.1 lysZ; acetylaminoadipate kinase/acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D APE_1462 lysY; N-acetyl-gamma-aminoadipyl-phosphate reductase/N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D APE_1464 lysJ; acetyl-lysine aminotransferase/acetylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D APE_1467.1 lysK; acetyl-lysine deacetylase/acetylornithine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00330 Arginine and proline metabolism [PATH:ape00330]
D APE_0954 conserved hypothetical protein K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D APE_1328.1 hyuA; hydantoin utilization protein A K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D APE_2528.1 hyuA; hydantoin utilization protein A K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D APE_1331 hyuB; hydantoin utilization protein B K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D APE_2530.1 hyuB; hydantoin utilization protein B K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D APE_0316.1 hypothetical protein K01480 speB; agmatinase [EC:3.5.3.11]
D APE_1637.1 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D APE_0767.1 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D APE_0079 speH; S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D APE_0639.1 speH; S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D APE_0146.1 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D APE_0807.1 delta-1-pyrroline-5-carboxylate dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism
D APE_2035.1 cobD; threonine-phosphate decarboxylase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00350 Tyrosine metabolism [PATH:ape00350]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2035.1 cobD; threonine-phosphate decarboxylase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D APE_0412 hypothetical protein K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00360 Phenylalanine metabolism [PATH:ape00360]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2035.1 cobD; threonine-phosphate decarboxylase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00380 Tryptophan metabolism [PATH:ape00380]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_1275 tnaA; tryptophanase K01667 tnaA; tryptophanase [EC:4.1.99.1]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:ape00400]
D APE_0581.1 aroG; phospho-2-dehydro-3-deoxyheptonate aldolase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D APE_0579 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D APE_0577 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D APE_0572 aroK; shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D APE_0569 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D APE_1404.1 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D APE_0564 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D APE_2553.1 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D APE_2555 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D APE_2551 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D APE_2547 trpF; N-(5'-phosphoribosyl) anthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D APE_2546 trpC; indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D APE_2550 trpA; tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D APE_2548 trpB; tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D APE_2316 trpB; tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D APE_0562.1 putative prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2035.1 cobD; threonine-phosphate decarboxylase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:ape00410]
D APE_0412 hypothetical protein K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D APE_0457 class-III aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D APE_1937.1 conserved hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
C 00430 Taurine and hypotaurine metabolism
D APE_0137 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:ape00450]
D APE_2068 metB; cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D APE_2048 metE; methylcobalamin:homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D APE_2050.1 putative methylcobalamin:homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D APE_1226 metC; cystathionine gamma-lyase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D APE_2023 csd; cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D APE_1061.1 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D APE_1197.1 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D APE_1129 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:ape00460]
D APE_0137 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D APE_1962.1 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APE_0528 acetamidase/formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
C 00470 D-Amino acid metabolism
C 00480 Glutathione metabolism [PATH:ape00480]
D APE_0137 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D APE_2450.1 pepA; leucine aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D APE_0689.1 isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D APE_0767.1 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:ape00730]
D APE_2400.1 thiDN; trifunctional ThiDN protein K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D APE_0465.1 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D APE_2149.1 thiazole biosynthetic enzyme Thi4 K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D APE_0235.1 thiL; putative thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D APE_0781.1 conserved hypothetical protein K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
D APE_0981.1 adkA; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D APE_0669.1 tenA; transcriptional activator TenA homolog K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
C 00740 Riboflavin metabolism [PATH:ape00740]
D APE_1365.1 GTP cyclohydrolase III K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D APE_1279.1 pyrimidine nucleotide reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D APE_0986.1 ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D APE_1366.1 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D APE_0988 ribC; riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D APE_2112.1 conserved hypothetical protein K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D APE_2281.1 putative cytidylyltransferase K14656 ribL; FAD synthetase [EC:2.7.7.2]
D APE_1481.1 nudF; ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D APE_2080.1 nudF; ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D APE_1647 probable aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:ape00750]
D APE_1488.1 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D APE_2286 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D APE_0246.1 pdxS; pyridoxal 5'-phosphate biosynthesis protein K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D APE_0244.1 pdxT; pyridoxal 5'-phosphate biosynthesis protein K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:ape00760]
D APE_1273.1 conserved hypothetical protein K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D APE_0801.1 surE; 5'(3')-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D APE_0513.1 nadM; nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D APE_1986.1 nadM; nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D APE_1958.1 nadE; NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D APE_1782.1 npdA; NAD-dependent deacetylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D APE_1104.1 ppnK; inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D APE_2520.1 maiA; maleate cis-trans isomerase K01799 nicE; maleate isomerase [EC:5.2.1.1]
C 00770 Pantothenate and CoA biosynthesis [PATH:ape00770]
D APE_2509 putative acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D APE_0013.1 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D APE_0676 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D APE_0677.1 panE; 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D APE_1939.1 conserved hypothetical protein K06982 pok; pantoate kinase [EC:2.7.1.169]
D APE_1937.1 conserved hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D APE_1959.1 dfp; coenzyme A biosynthesis bifunctional protein CoaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D APE_0256 conserved hypothetical protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D APE_0412 hypothetical protein K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00780 Biotin metabolism [PATH:ape00780]
D APE_0912 putative dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APE_2503.1 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00785 Lipoic acid metabolism [PATH:ape00785]
D APE_2344.1 lipA; lipoic acid synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D APE_2341 lipB; lipoate-protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D APE_2342.1 lipB; lipoate-protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_1677.1 pdhA; pyruvate dehydrogenase E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APE_1674 pdhB; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APE_1671 pdhC; pyruvate dehydrogenase complex, E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D APE_2124.1 gcvPA; glycine cleavage system P-protein subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D APE_2121.1 gcvPB; glycine cleavage system P-protein subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D APE_1695.1 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D APE_0951.1 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:ape00790]
D APE_1470.1 conserved hypothetical protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D APE_2308 conserved hypothetical protein K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D APE_2323 conserved hypothetical protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D APE_1512 conserved hypothetical protein K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D APE_2425 conserved hypothetical protein K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D APE_0478.1 moaA; molybdenum cofactor biosynthesis protein MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D APE_1350.1 moaC; molybdenum cofactor biosynthesis protein MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D APE_0603 molybdopterin converting factor K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12]
D APE_0077 mogA; molybdopterin biosynthesis protein MogA K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D APE_0450 moeA; molybdopterin biosynthesis protein MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D APE_2223 PucB homolog K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
C 00670 One carbon pool by folate [PATH:ape00670]
D APE_1962.1 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APE_1695.1 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D APE_2064.1 thyX; thymidylate synthase ThyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D APE_0157 conserved hypothetical protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
D APE_1596 mat; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D APE_0624.1 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D APE_2124.1 gcvPA; glycine cleavage system P-protein subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D APE_2121.1 gcvPB; glycine cleavage system P-protein subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0951.1 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D APE_1223.1 cystathionine beta-synthase K01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]
D APE_1586 cysK; cysteine synthase K10150 cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
D APE_1226 metC; cystathionine gamma-lyase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:ape00860]
D APE_2317.1 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APE_2296 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D APE_2130.1 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D APE_2299.1 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D APE_2300.1 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D APE_2298.1 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D APE_1493 hemD; putative uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D APE_0236.1 cobA; uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D APE_1491.1 sirC; precorrin-2 dehydrogenase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D APE_1652 PqqE homolog K22226 ahbC; Fe-coproporphyrin III synthase
D APE_1655 PqqE homolog K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D APE_1878 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D APE_1694.1 cytochrome AA3 controlling protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D APE_0166.1 ATP:cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D APE_2039.1 cbiB; cobalamin biosynthesis protein CbiB K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D APE_2034.1 cobY; nucleoside triphosphate:adenosylcobinamide-phosphate guanylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D APE_2037.1 cobS; cobalamin synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D APE_1457 conserved hypothetical protein K03594 bfr; bacterioferritin [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:ape00130]
D APE_1570 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D APE_1571.1 ubiD; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D APE_1647 probable aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D APE_0712.1 menC; O-succinylbenzoate synthase K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D APE_0252 conserved hypothetical protein K18285 mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]
D APE_0249.1 conserved hypothetical protein K11784 mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]
D APE_0248.1 conserved hypothetical protein K11785 mqnD; 5,8-dihydroxy-2-naphthoate synthase [EC:4.1.99.29]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:ape00900]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_1873.1 putative hydroxymethylglutaryl-coenzyme A synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D APE_1869 hmgA; 3-hydroxy-3-methylglutaryl-coenzyme A reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D APE_2439 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D APE_1768.1 isopentenyl phosphate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D APE_2087.1 putative aconitase, subunit K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182]
D APE_2089 putative aconitase, subunit K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182]
D APE_2078 conserved hypothetical protein K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]
D APE_1647 probable aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D APE_1765.1 fni; isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D APE_1764.1 fgs; farnesylgeranyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D APE_1385 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation [PATH:ape00907]
D APE_1872.1 putative 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D APE_0583 putative transketolase C-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APE_0586.1 putative transketolase N-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:ape00523]
D APE_1181 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1208.1 putative nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_2291 putative sugar-phosphate nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1202.1 putative nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D APE_1180 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D APE_1178 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D APE_1179.1 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D APE_1180 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
D APE_0336.1 penicillin acylase II precursor K01434 pac; penicillin G amidase [EC:3.5.1.11]
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:ape00261]
D APE_1197.1 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D APE_1140.1 lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D APE_1143 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D APE_1023.1 dapA; putative dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:ape00521]
D APE_2091.1 ATP-dependent glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D APE_0317.1 phospho-sugar mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D APE_1517 ino1; inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D APE_1798.1 fbpA; fructose-1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D APE_1181 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1208.1 putative nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_2291 putative sugar-phosphate nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1202.1 putative nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D APE_1180 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D APE_1178 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D APE_1179.1 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D APE_2091.1 ATP-dependent glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis [PATH:ape00525]
D APE_1181 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1208.1 putative nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_2291 putative sugar-phosphate nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D APE_1202.1 putative nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D APE_1180 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:ape00401]
D APE_0562.1 putative prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2035.1 cobD; threonine-phosphate decarboxylase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D APE_2553.1 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D APE_2555 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D APE_0912 putative dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APE_2503.1 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites
D APE_1596 mat; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:ape00362]
D APE_1872.1 putative 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D APE_2519.1 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:ape00627]
D APE_1591.1 putative acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D APE_1647 probable aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
D APE_2519.1 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
C 00623 Toluene degradation
C 00622 Xylene degradation [PATH:ape00622]
D APE_2519.1 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
D APE_1872.1 putative 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 00643 Styrene degradation [PATH:ape00643]
D APE_2519.1 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
D APE_2468.1 putative propionate CoA-transferase K01026 pct; propionate CoA-transferase [EC:2.8.3.1]
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:ape03020]
D APE_1856 rpoB; DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
D APE_1853.1 rpoA1; DNA-directed RNA polymerase subunit A K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D APE_1852.1 rpoA2; DNA-directed RNA polymerase subunit A K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D APE_1744.1 rpoD; DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D APE_0443.1 rpoL; DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D APE_0257 rpoE1; DNA-directed RNA polymerase subunit E K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D APE_0549.1 rpoF; DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D APE_2015.1 hypothetical protein K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
D APE_1856a rpoH; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D APE_0914 rpoK; DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D APE_1749a rpoN; DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D APE_1629a.1 hypothetical protein K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:ape03022]
D APE_0787.1 tfb; putative transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D APE_2443.1 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D APE_1862.1 tbp; TATA-box binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D APE_2004.1 transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D APE_0322.1 putative DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:ape03010]
D APE_1750 rps2p; 30S ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2
D APE_0363 rps3p; 30S ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3
D APE_1739.1 rps4p; 30S ribosomal protein S4P K02986 RP-S4; small subunit ribosomal protein S4
D APE_0346 rps5p; 30S ribosomal protein S5P K02988 RP-S5; small subunit ribosomal protein S5
D APE_1846.1 rps7p; 30S ribosomal protein S7P K02992 RP-S7; small subunit ribosomal protein S7
D APE_0352.1 rps8p; 30S ribosomal protein S8P K02994 RP-S8; small subunit ribosomal protein S8
D APE_1749 rps9p; 30S ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9
D APE_1842 rps10p; 30S ribosomal protein S10P K02946 RP-S10; small subunit ribosomal protein S10
D APE_1742.1 rps11p; 30S ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11
D APE_1849 rps12p; 30S ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12
D APE_1737.1 rps13p; 30S ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13
D APE_0352a rps14p; 30S ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14
D APE_1139 rps15p; 30S ribosomal protein S15P/S13e K02956 RP-S15; small subunit ribosomal protein S15
D APE_0360.1 rps17p; 30S ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17
D APE_0367.1 rps19p; 30S ribosomal protein S19P K02965 RP-S19; small subunit ribosomal protein S19
D APE_1154.1 rps3ae; 30S ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D APE_0356.1 rps4e; 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D APE_2371.1 rps6e; 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D APE_0789 rps8e; 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D APE_2071a rps17e; 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D APE_1090 rps19e; 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D APE_1132.1 rps24e; 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D APE_2470 rps25e; 30S ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e
D APE_2328a rps26e; 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e
D APE_0436a rps27e; 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D APE_1132a rps27ae; 30S ribosomal protein S27Ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D APE_2379b.1 rps28e; 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D APE_2199a rps30e; 30S ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
D APE_2173.1 rpl1p; 50S ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1
D APE_0218 rpl2p; 50S ribosomal protein L2P K02886 RP-L2; large subunit ribosomal protein L2
D APE_0227 rpl3p; 50S ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3
D APE_0354.1 rpl5p; 50S ribosomal protein L5P K02931 RP-L5; large subunit ribosomal protein L5
D APE_0350 rpl6p; 50S ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6
D APE_2171.1 rplP0; 50S ribosomal protein P0 K02864 RP-L10; large subunit ribosomal protein L10
D APE_2174 rpl11p; 50S ribosomal protein L11P K02867 RP-L11; large subunit ribosomal protein L11
D APE_2170 rpl12p; 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12
D APE_1747 rpl13p; 50S ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13
D APE_0359 rpl14p; 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14
D APE_0343 rpl15p; 50S ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15
D APE_0347 rpl18p; 50S ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18
D APE_0365 rpl22p; 50S ribosomal protein L22P K02890 RP-L22; large subunit ribosomal protein L22
D APE_0228a.1 rpl23p; 50S ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23
D APE_0358 rpl24p; 50S ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24
D APE_0362a rpl29p; 50S ribosomal protein L29P K02904 RP-L29; large subunit ribosomal protein L29
D APE_0345.1 rpl30p; 50S ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30
D APE_0228.1 rpl4p; 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e
D APE_1818 rpl7ae; 50S ribosomal protein L7Ae/small nucleolar RNP protein Snu13p/Nhp2P K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D APE_0449 rpl10e; 50S ribosomal protein L10e K02866 RP-L10e; large subunit ribosomal protein L10e
D APE_0537a rpl13e; 50S ribosomal protein L13e K02873 RP-L13e; large subunit ribosomal protein L13e
D APE_0976.1 rpl14e; 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e
D APE_1452 rpl15e; 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D APE_1746 rpl18e; 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D APE_0348 rpl19e; 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D APE_0546a rpl21e; 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D APE_2379a rpl24e; 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D APE_1851.1 rpl30e; 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e
D APE_1087.1 rpl31e; 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D APE_0349 rpl32e; 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D APE_0978a rpl34e; 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e
D APE_2324.1 rpl35ae; 50S ribosomal protein L35Ae K02917 RP-L35Ae; large subunit ribosomal protein L35Ae
D APE_0525b rpl37e; 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D APE_1443a rpl37ae; 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D APE_0179a rpl38e; 50S ribosomal protein L38e K02923 RP-L38e; large subunit ribosomal protein L38e
D APE_1087a rpl39e; 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D APE_0113a rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D APE_0436b.1 rpl44e; 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D APE_1084a rplX; 50S ribosomal protein LX K02944 RP-LX; large subunit ribosomal protein LX
D APE_rRNA05 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D APE_rRNA03 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D APE_rRNA01 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:ape00970]
D APE_tRNA09 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APE_tRNA18 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APE_tRNA37 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APE_tRNA04 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA22 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA30 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA38 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA47 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA14 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D APE_tRNA13 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D APE_tRNA42 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D APE_tRNA27 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D APE_tRNA45 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D APE_tRNA32 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D APE_tRNA41 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D APE_tRNA19 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APE_tRNA28 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APE_tRNA46 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APE_tRNA43 tRNA-His K14226 tRNA-His; tRNA His
D APE_tRNA23 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D APE_tRNA12 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA17 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA20 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA36 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA40 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA05 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APE_tRNA35 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APE_tRNA07 tRNA-Met K14230 tRNA-Met; tRNA Met
D APE_tRNA16 tRNA-Met K14230 tRNA-Met; tRNA Met
D APE_tRNA31 tRNA-Met K14230 tRNA-Met; tRNA Met
D APE_tRNA25 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D APE_tRNA02 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APE_tRNA10 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APE_tRNA33 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APE_tRNA03 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA11 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA24 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA34 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA01 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA06 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA26 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA29 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA15 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D APE_tRNA44 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D APE_tRNA08 tRNA-Val K14237 tRNA-Val; tRNA Val
D APE_tRNA21 tRNA-Val K14237 tRNA-Val; tRNA Val
D APE_tRNA39 tRNA-Val K14237 tRNA-Val; tRNA Val
D APE_2317.1 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APE_1717.1 gatA; glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D APE_1718 gatB; glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D APE_1716 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D APE_2200 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D APE_2202 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D APE_2166 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D APE_2192.1 aspS; aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D APE_1639 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D APE_0809.1 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D APE_1976.1 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D APE_1592.1 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D APE_1129 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D APE_1805.1 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D APE_1015 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APE_0374 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D APE_0161.1 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D APE_1756 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APE_2328 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D APE_0662.1 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D APE_2302.1 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D APE_2305 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D APE_2074.1 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APE_2461.1 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport [PATH:ape03013]
D APE_1844 tuf; elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D APE_0748.1 conserved hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3
D APE_2334.1 conserved hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3
C 03015 mRNA surveillance pathway [PATH:ape03015]
D APE_1988.1 prf1; peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
D APE_1800.1 pelA; pelota homolog K06965 PELO; protein pelota
C 03008 Ribosome biogenesis in eukaryotes [PATH:ape03008]
D APE_1443.1 conserved hypothetical protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D APE_2199.1 snoRNA binding protein K14564 NOP56; nucleolar protein 56
D APE_0433a small nucleolar RNP protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D APE_0502 ribosome biogenesis protein NEP1 K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
D APE_0362 rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D APE_1161.1 rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D APE_1450.1 rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D APE_0510.1 putative GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein
D APE_0748.1 conserved hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3
D APE_2334.1 conserved hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3
D APE_1085 translation initiation factor 6 K03264 EIF6; translation initiation factor 6
D APE_1167.1 conserved hypothetical protein K14574 SDO1; ribosome maturation protein SDO1
D APE_2094.1 conserved hypothetical protein K18532 AK6; adenylate kinase [EC:2.7.4.3]
D APE_0751 conserved hypothetical protein K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D APE_1602.1 putative kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:ape03060]
D APE_0983.1 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D APE_1735 signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D APE_srpRNA01 RNA component of signal recognition particle K01983 ffs; SRP RNA
D APE_1081.1 probable signal recognition particle protein K03110 ftsY; fused signal recognition particle receptor
D APE_2176a secE; preprotein translocase SecE subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D APE_0772 signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19
D APE_2165 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D APE_2139a twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APE_2154a twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APE_2154.1 twin-arginine translocation protein, TatC K03118 tatC; sec-independent protein translocase protein TatC
D APE_1796.1 signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum [PATH:ape04141]
D APE_2176a secE; preprotein translocase SecE subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D APE_1367 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_2474.1 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_1950.1 small heat shock protein K13993 HSP20; HSP20 family protein
D APE_0436.1 aif2a; translation initiation factor 2 alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
D APE_0113a rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D APE_1132a rps27ae; 30S ribosomal protein S27Ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 04122 Sulfur relay system [PATH:ape04122]
D APE_2595.1 thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D APE_0478.1 moaA; molybdenum cofactor biosynthesis protein MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D APE_0603 molybdopterin converting factor K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12]
D APE_1594 putative ATP-dependent adenyltransferase K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D APE_1350.1 moaC; molybdenum cofactor biosynthesis protein MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D APE_0077 mogA; molybdopterin biosynthesis protein MogA K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D APE_0465.1 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D APE_2086a hypothetical protein K03154 thiS; sulfur carrier protein
C 03050 Proteasome [PATH:ape03050]
D APE_2012 pan; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D APE_1449 psmA; proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D APE_0507.1 psmB; proteasome beta subunit precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D APE_0521.1 psmB; proteasome beta subunit precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:ape03018]
D APE_0445 exosome complex RNA-binding protein Cs14 homologue K07573 CSL4; exosome complex component CSL4
D APE_1448 exosome complex RNA-binding protein Rrp4 homologue K03679 RRP4; exosome complex component RRP4
D APE_1445 exosome complex exonuclease Rrp42 homologue K12589 RRP42; exosome complex component RRP42
D APE_1447 exosome complex exonuclease Rrp41 homologue K11600 RRP41; exosome complex component RRP41
D APE_2458 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APE_1353.1 ATP-dependent helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:ape03030]
D APE_2096.1 exosome complex RNA helicase DnaG homologue K02316 dnaG; DNA primase [EC:2.7.7.101]
D APE_0496.1 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D APE_0099 family B DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D APE_2098.1 family B DNA polymerase II K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D APE_2229.1 DNA polymerase II K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D APE_0188.1 minichromosome maintenance protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D APE_0438.1 priA; DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D APE_0667 priB; putative DNA primase large subunit K18882 priL; DNA primase large subunit
D APE_0162 DNA polymerase sliding clamp A K04802 PCNA; proliferating cell nuclear antigen
D APE_0441.1 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen
D APE_2182 DNA polymerase sliding clamp B1 K04802 PCNA; proliferating cell nuclear antigen
D APE_1522.1 rfcS; replication factor C small subunit K04801 rfcS; replication factor C small subunit
D APE_1524.1 rfcL; replication factor C large subunit K04800 rfcL; replication factor C large subunit
D APE_0115.1 fen; flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D APE_1094.1 ADP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:ape03410]
D APE_0150.1 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D APE_0875.1 U/G and T/G mismatch-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D APE_2247 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D APE_0162 DNA polymerase sliding clamp A K04802 PCNA; proliferating cell nuclear antigen
D APE_0441.1 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen
D APE_2182 DNA polymerase sliding clamp B1 K04802 PCNA; proliferating cell nuclear antigen
D APE_0115.1 fen; flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D APE_1094.1 ADP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D APE_0275.1 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D APE_0427.1 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D APE_2104.1 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
C 03420 Nucleotide excision repair [PATH:ape03420]
D APE_0322.1 putative DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D APE_1436.1 repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D APE_0162 DNA polymerase sliding clamp A K04802 PCNA; proliferating cell nuclear antigen
D APE_0441.1 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen
D APE_2182 DNA polymerase sliding clamp B1 K04802 PCNA; proliferating cell nuclear antigen
D APE_1094.1 ADP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:ape03430]
D APE_0162 DNA polymerase sliding clamp A K04802 PCNA; proliferating cell nuclear antigen
D APE_0441.1 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen
D APE_2182 DNA polymerase sliding clamp B1 K04802 PCNA; proliferating cell nuclear antigen
D APE_1094.1 ADP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination
C 03450 Non-homologous end-joining
D APE_0115.1 fen; flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
D APE_1436.1 repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
D APE_0256a.1 rpoE2; DNA-directed RNA polymerase subunit E K15171 SUPT4H1; transcription elongation factor SPT4
D APE_2176.1 putative transcription antitermination protein NusG K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus and Alphavirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03273 Virion - Lassa virus and SFTS virus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:ape02010]
D APE_0272.1 modA; molybdate ABC transporter, molybdate-binding protein ModA precursor K02020 modA; molybdate transport system substrate-binding protein
D APE_0270.1 modB; molybdate ABC transporter, permease protein ModB K02018 modB; molybdate transport system permease protein
D APE_1728 ABC transporter, substrate binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D APE_1730.1 ABC transporter, permease protein K02011 afuB; iron(III) transport system permease protein
D APE_1732 ABC transporter, ATP binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D APE_0945.1 spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein precursor K11069 potD; spermidine/putrescine transport system substrate-binding protein
D APE_0941 spermidine/putrescine ABC transporter, permease protein K11070 potC; spermidine/putrescine transport system permease protein
D APE_0943 spermidine/putrescine ABC transporter, permease protein K11071 potB; spermidine/putrescine transport system permease protein
D APE_0944.1 spermidine/putrescine ABC transporter, ATP binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D APE_0043.1 ABC transporter, ATP binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D APE_1635.1 ABC transporter, ATP binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D APE_0061.1 conserved hypothetical protein K07335 bmpA; basic membrane protein A and related proteins
D APE_2592.1 membrane lipoprotein family protein K07335 bmpA; basic membrane protein A and related proteins
D APE_0065 ABC transporter, permease protein K23535 nupB; general nucleoside transport system permease protein
D APE_2587.1 ABC transporter, permease protein K23535 nupB; general nucleoside transport system permease protein
D APE_0067.1 ABC transporter, permease protein K23536 nupC; general nucleoside transport system permease protein
D APE_2586.1 ABC transporter, permease protein K23536 nupC; general nucleoside transport system permease protein
D APE_0063 ABC transporter, ATP binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D APE_2588 ABC transporter, ATP binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D APE_2254.1 probable ABC transporter, substrate binding protein K17237 inoE; inositol-phosphate transport system substrate-binding protein
D APE_2253.1 probable ABC transporter, permease protein K17238 inoF; inositol-phosphate transport system permease protein
D APE_2252.1 probable ABC transporter, permease protein K17239 inoG; inositol-phosphate transport system permease protein
D APE_2060.1 ABC transporter, ATP binding protein K17240 inoK; inositol-phosphate transport system ATP-binding protein
D APE_0045 pstS; phosphate ABC transporter, phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D APE_0047.1 pstC; phosphate ABC transporter, permease protein K02037 pstC; phosphate transport system permease protein
D APE_0048 pstA; phosphate ABC transporter, permease protein K02038 pstA; phosphate transport system permease protein
D APE_0050 pstB; phosphate ABC transporter, ATP binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D APE_0917 livK; branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein precursor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_1303.1 ABC transporter, substrate binding protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_2521.1 livK; branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein precursor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_0922 livH; branched-chain amino acid ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_1305 ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_2522.1 livH; branched-chain amino acid ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_0924.1 livM; branched-chain amino acid ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_1304.1 ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_2523.1 livM; branched-chain amino acid ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_0919 livG; branched-chain amino acid ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_1308 ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_2524.1 livG; branched-chain amino acid ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_0921 livF; branched-chain amino acid ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_1301.1 ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_2526 livF; branched-chain amino acid ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_2155.1 conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein
D APE_2403.1 hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:ape03070]
D APE_0983.1 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D APE_1081.1 probable signal recognition particle protein K03110 ftsY; fused signal recognition particle receptor
D APE_1735 signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D APE_2139a twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APE_2154a twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APE_2154.1 twin-arginine translocation protein, TatC K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:ape02020]
D APE_0045 pstS; phosphate ABC transporter, phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D APE_1694.1 cytochrome AA3 controlling protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D APE_0311 mcl; malyl-CoA lyase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D APE_1715.1 citG; 2-(5'-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D APE_0392 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D APE_1288.1 narG; nitrate reductase, alpha subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D APE_1294.1 narH; nitrate reductase, beta subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D APE_1300.1 narJ; nitrate reductase delta subunit K00373 narJ; nitrate reductase molybdenum cofactor assembly chaperone NarJ/NarW
D APE_2142.1 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APE_2380.1 hypothetical protein K02106 atoE; short-chain fatty acids transporter
D APE_2381.1 hypothetical protein K02106 atoE; short-chain fatty acids transporter
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04081 Hormone signaling
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
D APE_2176a secE; preprotein translocase SecE subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C 04142 Lysosome
C 04146 Peroxisome [PATH:ape04146]
D APE_1307 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_1310 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_2284.1 fadD; long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_0308.1 eapA; alkyldihydroxyacetonephosphate synthase K00803 AGPS; alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]
D APE_2439 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D APE_0689.1 isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D APE_0741 superoxide dismutase [Mn/Fe] K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:ape02024]
D APE_2553.1 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D APE_2555 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D APE_0917 livK; branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein precursor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_1303.1 ABC transporter, substrate binding protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_2521.1 livK; branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein precursor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_0922 livH; branched-chain amino acid ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_1305 ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_2522.1 livH; branched-chain amino acid ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_0924.1 livM; branched-chain amino acid ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_1304.1 ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_2523.1 livM; branched-chain amino acid ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_0919 livG; branched-chain amino acid ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_1308 ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_2524.1 livG; branched-chain amino acid ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_0921 livF; branched-chain amino acid ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_1301.1 ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_2526 livF; branched-chain amino acid ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_1307 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_1310 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_2284.1 fadD; long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_0304.1 ABC transporter, substrate-binding protein precursor K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_1390.1 ABC transporter, substrate-binding protein precursor K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_1583.1 oppA; oligopeptide ABC transporter, oligopeptide binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_2257 dppA; dipeptide ABC transporter, dipeptide-binding protein DppA K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_0303 ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_1395.1 ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_1582 oligopeptide ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_2258 dppB; dipeptide ABC transporter, permease protein DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_0302.1 ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_1396 ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_1581.1 oligopeptide ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_2260 dppC; dipeptide ABC transporter, permease protein DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_0301.1 ABC transporter, ATP binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_1399 ABC transporter, ATP binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_1578 oligopeptide ABC transporter, ATP binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_2261.1 dppD; dipeptide ABC transporter, ATP-binding protein DppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_0300.1 ABC transporter, ATP binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_1402.1 ABC transporter, ATP binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_1576 oligopeptide ABC transporter, ATP binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_2263.1 dppF; dipeptide ABC transporter, ATP-binding protein DppF K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_0983.1 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D APE_1081.1 probable signal recognition particle protein K03110 ftsY; fused signal recognition particle receptor
D APE_1735 signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D APE_2458 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04981 Folate transport and metabolism [PATH:ape04981]
D APE_0157 conserved hypothetical protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
D APE_1962.1 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 04980 Cobalamin transport and metabolism [PATH:ape04980]
D APE_0166.1 ATP:cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D APE_1683.1 transport system kinase K07588 MMAA; GTPase [EC:3.6.5.-]
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:ape01000]
C 01001 Protein kinases [BR:ape01001]
D APE_1136.1 putative protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D APE_0751 conserved hypothetical protein K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D APE_1602.1 putative kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 01009 Protein phosphatases and associated proteins [BR:ape01009]
D APE_1533.1 aif2b; translation initiation factor 2 beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2
D APE_0624.1 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D APE_0683 phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:ape01002]
D APE_2452 guaA; GMP synthase [glutamine-hydrolyzing] K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D APE_1205.1 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D APE_2041.1 putative asparagine synthetase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D APE_0319 protease I K26818 pfpI; archaeal arginyl aminopeptidase [EC:3.4.11.27]
D APE_0004 hypothetical protein K07052 K07052; CAAX protease family protein
D APE_2450.1 pepA; leucine aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D APE_0337.1 dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D APE_0632.1 conserved hypothetical protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D APE_1917 hypothetical protein K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D APE_1114.1 methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D APE_2081.1 aminopeptidase K19689 ampS; aminopeptidase [EC:3.4.11.-]
D APE_1775.1 carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D APE_1045.1 htpX; zinc metalloprotease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D APE_0147.1 conserved hypothetical protein K06974 amzA; archaemetzincin [EC:3.4.-.-]
D APE_0314.1 D-aminopeptidase DppA K16203 dppA1; D-amino peptidase [EC:3.4.11.-]
D APE_1547.1 acylamino-acid-releasing enzyme K01303 APEH; acylaminoacyl-peptidase [EC:3.4.19.1]
D APE_1796.1 signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D APE_0336.1 penicillin acylase II precursor K01434 pac; penicillin G amidase [EC:3.5.1.11]
D APE_1877.1 putative subfamily S26B peptidase K07059 K07059; rhomboid family protein
D APE_1449 psmA; proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D APE_0507.1 psmB; proteasome beta subunit precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D APE_0521.1 psmB; proteasome beta subunit precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D APE_0137 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D APE_0091 probable peptidase K03592 pmbA; PmbA protein
D APE_0089.1 probable peptidase K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:ape01003]
D APE_0426.1 dolichol-phosphate mannosyltransferase K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]
D APE_0889.1 mpgs; mannosyl-3-phosphoglycerate synthase K05947 E2.4.1.217; mannosyl-3-phosphoglycerate synthase [EC:2.4.1.217]
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins
C 01004 Lipid biosynthesis proteins [BR:ape01004]
D APE_0912 putative dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APE_2503.1 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APE_1346.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_2604a.1 acsA; acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D APE_1307 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_1310 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_2284.1 fadD; long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:ape01006]
D APE_1764.1 fgs; farnesylgeranyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D APE_1385 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D APE_1570 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D APE_1878 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:ape01007]
D APE_0161.1 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D APE_2317.1 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APE_2074.1 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APE_2461.1 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D APE_1592.1 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D APE_1756 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APE_1129 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D APE_0374 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D APE_1805.1 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D APE_1015 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APE_2192.1 aspS; aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D APE_0662.1 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D APE_1639 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D APE_1976.1 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D APE_2328 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D APE_0809.1 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D APE_2166 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D APE_2302.1 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D APE_2305 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D APE_0674.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2248.1 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APE_2035.1 cobD; threonine-phosphate decarboxylase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D APE_1464 lysJ; acetyl-lysine aminotransferase/acetylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D APE_0457 class-III aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D APE_2130.1 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D APE_2299.1 hemL; glutamate-1-semialdehyde aminotransferase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:ape03000]
D APE_0872.1 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_2002 cytosine-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_1862.1 tbp; TATA-box binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D APE_1458a lysM; HTH-type transcriptional regulator LysM K06154 lysM; Lrp/AsnC family transcriptional regulator, involved in the regulation of lysine biosynthesis
D APE_2021.1 putative transcriptional regulator, Fur family K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D APE_0142 putative transcriptional regulator, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D APE_0025.1 putative transcriptional regulator, TrmB family K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D APE_0153.1 putative transcriptional regulator, TrmB family K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D APE_1237.1 putative CRISPR-associated DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D APE_0778 putative HTH-type transcriptional regulator K07728 K07728; putative transcriptional regulator
D APE_0197.1 putative HTH-type transcriptional regulator K07731 K07731; putative transcriptional regulator
D APE_0535 hypothetical protein K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D APE_2570.1 nikR; nickel responsive regulator K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D APE_0669.1 tenA; transcriptional activator TenA homolog K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
C 03021 Transcription machinery [BR:ape03021]
D APE_0787.1 tfb; putative transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D APE_2443.1 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D APE_1862.1 tbp; TATA-box binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D APE_2004.1 transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D APE_0322.1 putative DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D APE_0256a.1 rpoE2; DNA-directed RNA polymerase subunit E K15171 SUPT4H1; transcription elongation factor SPT4
D APE_2176.1 putative transcription antitermination protein NusG K15172 SUPT5H; transcription elongation factor SPT5
D APE_0791.1 putative ATP/GTP-binding protein K24104 GPN; GPN-loop GTPase
D APE_1850 NusA protein homolog K02600 nusA; transcription termination/antitermination protein NusA
D APE_1853.1 rpoA1; DNA-directed RNA polymerase subunit A K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D APE_1852.1 rpoA2; DNA-directed RNA polymerase subunit A K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D APE_1856 rpoB; DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
D APE_1744.1 rpoD; DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D APE_0257 rpoE1; DNA-directed RNA polymerase subunit E K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D APE_0549.1 rpoF; DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D APE_2015.1 hypothetical protein K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
D APE_1856a rpoH; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D APE_0914 rpoK; DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D APE_0443.1 rpoL; DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D APE_1749a rpoN; DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D APE_1629a.1 hypothetical protein K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D APE_0442.1 tfs; archaeal transcription factor S K03057 tfs; transcription factor S
D APE_1007a hypothetical protein K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:ape03019]
D APE_0256a.1 rpoE2; DNA-directed RNA polymerase subunit E K15171 SUPT4H1; transcription elongation factor SPT4
D APE_2176.1 putative transcription antitermination protein NusG K15172 SUPT5H; transcription elongation factor SPT5
D APE_1367 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_2474.1 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_1800.1 pelA; pelota homolog K06965 PELO; protein pelota
D APE_1988.1 prf1; peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
D APE_1844 tuf; elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D APE_0445 exosome complex RNA-binding protein Cs14 homologue K07573 CSL4; exosome complex component CSL4
D APE_1448 exosome complex RNA-binding protein Rrp4 homologue K03679 RRP4; exosome complex component RRP4
D APE_1447 exosome complex exonuclease Rrp41 homologue K11600 RRP41; exosome complex component RRP41
D APE_1445 exosome complex exonuclease Rrp42 homologue K12589 RRP42; exosome complex component RRP42
D APE_1353.1 ATP-dependent helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D APE_2458 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 03041 Spliceosome [BR:ape03041]
D APE_1949.1 zinc-finger protein ZPR1 homolog K06874 ZPR1; zinc finger protein ZPR1
C 03011 Ribosome [BR:ape03011]
D APE_1154.1 rps3ae; 30S ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D APE_0356.1 rps4e; 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D APE_2371.1 rps6e; 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D APE_0789 rps8e; 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D APE_2071a rps17e; 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D APE_1090 rps19e; 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D APE_1132.1 rps24e; 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D APE_2470 rps25e; 30S ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e
D APE_2328a rps26e; 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e
D APE_0436a rps27e; 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D APE_1132a rps27ae; 30S ribosomal protein S27Ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D APE_2379b.1 rps28e; 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D APE_2199a rps30e; 30S ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
D APE_0228.1 rpl4p; 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e
D APE_1818 rpl7ae; 50S ribosomal protein L7Ae/small nucleolar RNP protein Snu13p/Nhp2P K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D APE_0449 rpl10e; 50S ribosomal protein L10e K02866 RP-L10e; large subunit ribosomal protein L10e
D APE_0537a rpl13e; 50S ribosomal protein L13e K02873 RP-L13e; large subunit ribosomal protein L13e
D APE_0976.1 rpl14e; 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e
D APE_1452 rpl15e; 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D APE_1746 rpl18e; 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D APE_0348 rpl19e; 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D APE_0546a rpl21e; 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D APE_2379a rpl24e; 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D APE_1851.1 rpl30e; 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e
D APE_1087.1 rpl31e; 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D APE_0349 rpl32e; 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D APE_0978a rpl34e; 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e
D APE_2324.1 rpl35ae; 50S ribosomal protein L35Ae K02917 RP-L35Ae; large subunit ribosomal protein L35Ae
D APE_0525b rpl37e; 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D APE_1443a rpl37ae; 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D APE_0179a rpl38e; 50S ribosomal protein L38e K02923 RP-L38e; large subunit ribosomal protein L38e
D APE_1087a rpl39e; 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D APE_0113a rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D APE_0436b.1 rpl44e; 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D APE_1750 rps2p; 30S ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2
D APE_0363 rps3p; 30S ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3
D APE_1739.1 rps4p; 30S ribosomal protein S4P K02986 RP-S4; small subunit ribosomal protein S4
D APE_0346 rps5p; 30S ribosomal protein S5P K02988 RP-S5; small subunit ribosomal protein S5
D APE_1846.1 rps7p; 30S ribosomal protein S7P K02992 RP-S7; small subunit ribosomal protein S7
D APE_0352.1 rps8p; 30S ribosomal protein S8P K02994 RP-S8; small subunit ribosomal protein S8
D APE_1749 rps9p; 30S ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9
D APE_1842 rps10p; 30S ribosomal protein S10P K02946 RP-S10; small subunit ribosomal protein S10
D APE_1742.1 rps11p; 30S ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11
D APE_1849 rps12p; 30S ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12
D APE_1737.1 rps13p; 30S ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13
D APE_0352a rps14p; 30S ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14
D APE_1139 rps15p; 30S ribosomal protein S15P/S13e K02956 RP-S15; small subunit ribosomal protein S15
D APE_0360.1 rps17p; 30S ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17
D APE_0367.1 rps19p; 30S ribosomal protein S19P K02965 RP-S19; small subunit ribosomal protein S19
D APE_2173.1 rpl1p; 50S ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1
D APE_0218 rpl2p; 50S ribosomal protein L2P K02886 RP-L2; large subunit ribosomal protein L2
D APE_0227 rpl3p; 50S ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3
D APE_0354.1 rpl5p; 50S ribosomal protein L5P K02931 RP-L5; large subunit ribosomal protein L5
D APE_0350 rpl6p; 50S ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6
D APE_2171.1 rplP0; 50S ribosomal protein P0 K02864 RP-L10; large subunit ribosomal protein L10
D APE_2174 rpl11p; 50S ribosomal protein L11P K02867 RP-L11; large subunit ribosomal protein L11
D APE_1747 rpl13p; 50S ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13
D APE_0359 rpl14p; 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14
D APE_0343 rpl15p; 50S ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15
D APE_0347 rpl18p; 50S ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18
D APE_0365 rpl22p; 50S ribosomal protein L22P K02890 RP-L22; large subunit ribosomal protein L22
D APE_0228a.1 rpl23p; 50S ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23
D APE_0358 rpl24p; 50S ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24
D APE_0362a rpl29p; 50S ribosomal protein L29P K02904 RP-L29; large subunit ribosomal protein L29
D APE_0345.1 rpl30p; 50S ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30
D APE_2170 rpl12p; 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12
D APE_1084a rplX; 50S ribosomal protein LX K02944 RP-LX; large subunit ribosomal protein LX
D APE_rRNA01 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D APE_rRNA05 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D APE_rRNA03 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:ape03009]
D APE_2199.1 snoRNA binding protein K14564 NOP56; nucleolar protein 56
D APE_0433a small nucleolar RNP protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D APE_1443.1 conserved hypothetical protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D APE_0502 ribosome biogenesis protein NEP1 K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
D APE_0754.1 conserved hypothetical protein K06961 KRR1; ribosomal RNA assembly protein
D APE_0751 conserved hypothetical protein K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D APE_1602.1 putative kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D APE_2094.1 conserved hypothetical protein K18532 AK6; adenylate kinase [EC:2.7.4.3]
D APE_1119.1 ABCE1 homolog K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D APE_0510.1 putative GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein
D APE_0362 rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D APE_1161.1 rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D APE_1450.1 rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D APE_0540.1 conserved hypothetical protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-]
D APE_1649.1 conserved hypothetical protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-]
D APE_1085 translation initiation factor 6 K03264 EIF6; translation initiation factor 6
D APE_0748.1 conserved hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3
D APE_2334.1 conserved hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3
D APE_1167.1 conserved hypothetical protein K14574 SDO1; ribosome maturation protein SDO1
D APE_1367 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_2474.1 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_0516.1 hypothetical protein K07565 NIP7; 60S ribosome subunit biogenesis protein NIP7
D APE_2196 snoRNA binding protein K04795 flpA; fibrillarin-like pre-rRNA processing protein
D APE_1818 rpl7ae; 50S ribosomal protein L7Ae/small nucleolar RNP protein Snu13p/Nhp2P K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D APE_1850 NusA protein homolog K02600 nusA; transcription termination/antitermination protein NusA
D APE_0553 ksgA; S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D APE_0141.1 conserved hypothetical protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D APE_1954 N-terminal acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D APE_2336.1 RNA-loop binding protein FAU-1 K22469 fau-1; ribonuclease FAU-1 [EC:3.1.26.-]
D APE_2007 hflX; putative GTP-binding protein HflX K03665 hflX; GTPase
D APE_2397 putative translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D APE_1091 conserved hypothetical protein K07574 yhbY; RNA-binding protein
D APE_1164 conserved hypothetical protein K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:ape03016]
D APE_0362 rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D APE_1161.1 rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D APE_1450.1 rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D APE_1092.1 rnp4; ribonuclease P protein component 4 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D APE_0636 putative metal dependent hydrolase K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D APE_1836.1 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D APE_1758.1 conserved hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D APE_0148.1 conserved hypothetical protein K24956 ZBTB8OS; protein archease
D APE_1844 tuf; elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D APE_2317.1 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APE_2328 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D APE_0374 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D APE_1015 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APE_1129 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D APE_1756 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APE_2166 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D APE_1639 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D APE_0809.1 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D APE_1976.1 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D APE_1592.1 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D APE_1805.1 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D APE_0662.1 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D APE_2302.1 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D APE_2305 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D APE_2074.1 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APE_2461.1 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D APE_1483.1 hypothetical protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D APE_0903.1 misacylated tRNAala hydrolase AlaX K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D APE_2495.1 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D APE_1530.1 MiaB homolog K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D APE_0782.1 trm1; N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D APE_0815.1 conserved hypothetical protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D APE_1106.1 conserved hypothetical protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D APE_2486.1 tRNA (m1A) methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D APE_1059 conserved hypothetical protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D APE_0816 conserved hypothetical protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D APE_0989.1 small nucleolar RNP protein Cbf5 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D APE_1819 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D APE_0546.1 putative pseudouridine synthase PsuX K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D APE_1136.1 putative protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D APE_1135 O-sialoglycoprotein endopeptidase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D APE_2397 putative translation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D APE_1156.1 conserved hypothetical protein K06963 TAN1; tRNA acetyltransferase TAN1
D APE_rnpRNA01 ribonuclease P RNA component K01978 rnpB; M1 RNA
D APE_1564.1 conserved hypothetical protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
D APE_1791.1 cca; tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D APE_0685 hypothetical protein K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D APE_1646.1 endA; tRNA-splicing endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D APE_1792 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D APE_0204.1 kptA; RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
D APE_0161.1 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D APE_2192.1 aspS; aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D APE_0797 conserved hypothetical protein K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D APE_0514 RNA (cytosine-C(5)-)-methyltransferase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D APE_0498 conserved hypothetical protein K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221]
D APE_0557 putative methyltransferase K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256]
D APE_1835 putative methyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D APE_2006.1 tRNA ribose 2'-O-methylase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D APE_2086 conserved hypothetical protein K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
D APE_1440a hypothetical protein K09741 pcc1; KEOPS complex subunit Pcc1
D APE_1470.1 conserved hypothetical protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D APE_2017 probable archaeosine tRNA-guanine transglycosylase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D APE_0465.1 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D APE_0656.1 conserved hypothetical protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D APE_1543 conserved hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D APE_2392.1 conserved hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
C 03012 Translation factors [BR:ape03012]
D APE_0748a translation initiation factor 1A K03236 EIF1A; translation initiation factor 1A
D APE_1629 protein translation factor SUI1 homolog K03113 EIF1; translation initiation factor 1
D APE_0436.1 aif2a; translation initiation factor 2 alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
D APE_1533.1 aif2b; translation initiation factor 2 beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2
D APE_2366.1 aif2g; translation initiation factor 2 gamma subunit K03242 EIF2S3; translation initiation factor 2 subunit 3
D APE_1047.1 putative translation initiation factor eIF-2B subunit K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
D APE_2085.1 translation initiation factor 5A K03263 EIF5A; translation initiation factor 5A
D APE_2374 infB; translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B
D APE_1085 translation initiation factor 6 K03264 EIF6; translation initiation factor 6
D APE_1844 tuf; elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D APE_2480.1 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta
D APE_1432 fusA; elongation factor 2 K03234 EEF2; elongation factor 2
D APE_0447.1 conserved hypothetical protein K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D APE_0421 conserved hypothetical protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D APE_1988.1 prf1; peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
D APE_0554.1 putative methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D APE_1661 pth; peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:ape03110]
D APE_0907.1 thermosome alpha subunit K22447 cct; archaeal chaperonin
D APE_2072.1 thermosome beta subunit K22447 cct; archaeal chaperonin
D APE_1950.1 small heat shock protein K13993 HSP20; HSP20 family protein
D APE_1084.1 pfdA; prefoldin alpha subunit K04797 pfdA; prefoldin alpha subunit
D APE_1440 pfdB; prefoldin beta subunit K04798 pfdB; prefoldin beta subunit
D APE_0517 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D APE_2430.1 thioredoxin K03671 TXN; thioredoxin
D APE_2496.1 trxA; thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:ape04131]
D APE_2377 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D APE_1367 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_2474.1 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_2165 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D APE_2176a secE; preprotein translocase SecE subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D APE_0489 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D APE_1844 tuf; elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:ape04121]
D APE_0113a rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D APE_1132a rps27ae; 30S ribosomal protein S27Ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D APE_2199a rps30e; 30S ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
C 03051 Proteasome [BR:ape03051]
D APE_1449 psmA; proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D APE_0507.1 psmB; proteasome beta subunit precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D APE_0521.1 psmB; proteasome beta subunit precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D APE_2012 pan; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:ape03032]
D APE_0162 DNA polymerase sliding clamp A K04802 PCNA; proliferating cell nuclear antigen
D APE_0441.1 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen
D APE_2182 DNA polymerase sliding clamp B1 K04802 PCNA; proliferating cell nuclear antigen
D APE_0115.1 fen; flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D APE_1094.1 ADP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D APE_0872.1 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_2002 cytosine-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_0433a small nucleolar RNP protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D APE_1436.1 repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D APE_2096.1 exosome complex RNA helicase DnaG homologue K02316 dnaG; DNA primase [EC:2.7.7.101]
D APE_0152.1 origin recognition complex subunit 2 Orc2 K10725 cdc6A; archaeal cell division control protein 6
D APE_0475.1 origin recognition complex subunit 1 Orc1 K10725 cdc6A; archaeal cell division control protein 6
D APE_0188.1 minichromosome maintenance protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D APE_0438.1 priA; DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D APE_0667 priB; putative DNA primase large subunit K18882 priL; DNA primase large subunit
D APE_0187 hypothetical protein K09723 ginS; DNA replication factor GINS
D APE_0496.1 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D APE_0099 family B DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D APE_2098.1 family B DNA polymerase II K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D APE_2229.1 DNA polymerase II K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D APE_1524.1 rfcL; replication factor C large subunit K04800 rfcL; replication factor C large subunit
D APE_1522.1 rfcS; replication factor C small subunit K04801 rfcS; replication factor C small subunit
D APE_0703.1 top6A; type II DNA topoisomerase VI subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D APE_0706.1 top6B; type II DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D APE_1794 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D APE_1340.1 rgy; reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-]
D APE_1376.1 rgy; reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-]
C 03036 Chromosome and associated proteins [BR:ape03036]
D APE_0872.1 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_2002 cytosine-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_0226.1 conserved hypothetical protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D APE_0322.1 putative DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D APE_0805 tyrosine recombinase XerC/XerD K04763 xerD; integrase/recombinase XerD
D APE_0230.1 MRP/NBP35 family protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
C 03400 DNA repair and recombination proteins [BR:ape03400]
D APE_0959 ogt; methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D APE_2247 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D APE_0875.1 U/G and T/G mismatch-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D APE_0150.1 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D APE_0162 DNA polymerase sliding clamp A K04802 PCNA; proliferating cell nuclear antigen
D APE_0441.1 DNA polymerase sliding clamp B2 K04802 PCNA; proliferating cell nuclear antigen
D APE_2182 DNA polymerase sliding clamp B1 K04802 PCNA; proliferating cell nuclear antigen
D APE_0115.1 fen; flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D APE_1094.1 ADP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D APE_0322.1 putative DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D APE_1436.1 repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D APE_2056.1 putative NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D APE_0069.1 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D APE_0427.1 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D APE_0275.1 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D APE_2104.1 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D APE_0506 nfi; endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D APE_0113 double-strand break repair protein MRE11 K03547 sbcD; DNA repair protein SbcD/Mre11
D APE_1240.1 cas1; putative CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D APE_0119 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D APE_0461 holliday junction resolvase K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D APE_0107 herA; bipolar DNA helicase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
D APE_0109.1 5' to 3' nuclease repair protein NurA K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
D APE_0191.1 hjm; holliday junction migration helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D APE_1794 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D APE_1353.1 ATP-dependent helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D APE_2144.1 putative ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D APE_2188.1 putative ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D APE_2062.1 ribonucleotide reductase, B12-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APE_1998 conserved hypothetical protein K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:ape03029]
D APE_0362 rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D APE_1161.1 rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D APE_1450.1 rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D APE_2074.1 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APE_1015 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APE_1639 glyS; glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D APE_1756 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APE_1717.1 gatA; glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D APE_1718 gatB; glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D APE_1716 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D APE_0230.1 MRP/NBP35 family protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D APE_1878 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D APE_1694.1 cytochrome AA3 controlling protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D APE_0796.1 putative SCO1 protein K07152 SCO1; protein SCO1
D APE_1721 putative SCO1 protein K07152 SCO1; protein SCO1
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:ape02000]
D APE_0272.1 modA; molybdate ABC transporter, molybdate-binding protein ModA precursor K02020 modA; molybdate transport system substrate-binding protein
D APE_0270.1 modB; molybdate ABC transporter, permease protein ModB K02018 modB; molybdate transport system permease protein
D APE_1728 ABC transporter, substrate binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D APE_1730.1 ABC transporter, permease protein K02011 afuB; iron(III) transport system permease protein
D APE_1732 ABC transporter, ATP binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D APE_0945.1 spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein precursor K11069 potD; spermidine/putrescine transport system substrate-binding protein
D APE_0941 spermidine/putrescine ABC transporter, permease protein K11070 potC; spermidine/putrescine transport system permease protein
D APE_0943 spermidine/putrescine ABC transporter, permease protein K11071 potB; spermidine/putrescine transport system permease protein
D APE_0944.1 spermidine/putrescine ABC transporter, ATP binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D APE_0043.1 ABC transporter, ATP binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D APE_1635.1 ABC transporter, ATP binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D APE_2254.1 probable ABC transporter, substrate binding protein K17237 inoE; inositol-phosphate transport system substrate-binding protein
D APE_2253.1 probable ABC transporter, permease protein K17238 inoF; inositol-phosphate transport system permease protein
D APE_2252.1 probable ABC transporter, permease protein K17239 inoG; inositol-phosphate transport system permease protein
D APE_2060.1 ABC transporter, ATP binding protein K17240 inoK; inositol-phosphate transport system ATP-binding protein
D APE_0061.1 conserved hypothetical protein K07335 bmpA; basic membrane protein A and related proteins
D APE_2592.1 membrane lipoprotein family protein K07335 bmpA; basic membrane protein A and related proteins
D APE_0065 ABC transporter, permease protein K23535 nupB; general nucleoside transport system permease protein
D APE_2587.1 ABC transporter, permease protein K23535 nupB; general nucleoside transport system permease protein
D APE_0067.1 ABC transporter, permease protein K23536 nupC; general nucleoside transport system permease protein
D APE_2586.1 ABC transporter, permease protein K23536 nupC; general nucleoside transport system permease protein
D APE_0063 ABC transporter, ATP binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D APE_2588 ABC transporter, ATP binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D APE_0035.1 ABC transporter, substrate binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D APE_1630.1 ABC transporter, substrate binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D APE_0038.1 ABC transporter, permease protein K02025 ABC.MS.P; multiple sugar transport system permease protein
D APE_1632 ABC transporter, permease protein K02025 ABC.MS.P; multiple sugar transport system permease protein
D APE_0040.1 ABC transporter, permease protein K02026 ABC.MS.P1; multiple sugar transport system permease protein
D APE_1633 ABC transporter, permease protein K02026 ABC.MS.P1; multiple sugar transport system permease protein
D APE_0045 pstS; phosphate ABC transporter, phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D APE_0047.1 pstC; phosphate ABC transporter, permease protein K02037 pstC; phosphate transport system permease protein
D APE_0048 pstA; phosphate ABC transporter, permease protein K02038 pstA; phosphate transport system permease protein
D APE_0050 pstB; phosphate ABC transporter, ATP binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D APE_0917 livK; branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein precursor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_1303.1 ABC transporter, substrate binding protein K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_2521.1 livK; branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein precursor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D APE_0922 livH; branched-chain amino acid ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_1305 ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_2522.1 livH; branched-chain amino acid ABC transporter, permease protein K01997 livH; branched-chain amino acid transport system permease protein
D APE_0924.1 livM; branched-chain amino acid ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_1304.1 ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_2523.1 livM; branched-chain amino acid ABC transporter, permease protein K01998 livM; branched-chain amino acid transport system permease protein
D APE_0919 livG; branched-chain amino acid ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_1308 ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_2524.1 livG; branched-chain amino acid ABC transporter, ATP binding protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D APE_0921 livF; branched-chain amino acid ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_1301.1 ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_2526 livF; branched-chain amino acid ABC transporter, ATP binding protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D APE_1893.1 ABC transporter, substrate binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D APE_1892 ABC transporter, permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D APE_1891.1 ABC transporter, ATP binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
D APE_0304.1 ABC transporter, substrate-binding protein precursor K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_1390.1 ABC transporter, substrate-binding protein precursor K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_1583.1 oppA; oligopeptide ABC transporter, oligopeptide binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_2257 dppA; dipeptide ABC transporter, dipeptide-binding protein DppA K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D APE_0303 ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_1395.1 ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_1582 oligopeptide ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_2258 dppB; dipeptide ABC transporter, permease protein DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D APE_0302.1 ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_1396 ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_1581.1 oligopeptide ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_2260 dppC; dipeptide ABC transporter, permease protein DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D APE_0301.1 ABC transporter, ATP binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_1399 ABC transporter, ATP binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_1578 oligopeptide ABC transporter, ATP binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_2261.1 dppD; dipeptide ABC transporter, ATP-binding protein DppD K02031 ddpD; peptide/nickel transport system ATP-binding protein
D APE_0300.1 ABC transporter, ATP binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_1402.1 ABC transporter, ATP binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_1576 oligopeptide ABC transporter, ATP binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_2263.1 dppF; dipeptide ABC transporter, ATP-binding protein DppF K02032 ddpF; peptide/nickel transport system ATP-binding protein
D APE_1049.1 putative ABC transporter, substrate binding protein K25034 btuF; cobalamin transport system substrate-binding protein
D APE_1053.1 putative ABC transporter, permease protein K25027 btuC; cobalamin transport system permease protein
D APE_1055.1 putative ABC transporter, ATP binding protein K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8]
D APE_2155.1 conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein
D APE_2403.1 hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein
D APE_0531.1 ABC transporter, substrate binding protein K02077 ABC.ZM.S; zinc/manganese transport system substrate-binding protein
D APE_0534.1 ABC transporter, permease protein K02075 ABC.ZM.P; zinc/manganese transport system permease protein
D APE_0532.1 ABC transporter, ATP binding protein K02074 ABC.ZM.A; zinc/manganese transport system ATP-binding protein
D APE_0470.1 hypothetical protein K25147 berB; beta-exotoxin I transport system permease protein
D APE_0471.1 ABC transporter, ATP binding protein K25148 berA; beta-exotoxin I transport system ATP-binding protein
D APE_1257 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_1550.1 ABC transporter, permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_1827.1 conserved hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_1828.1 conserved hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_1909.1 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_1932.1 ABC transporter, permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_2512 ABC transporter, permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_2514 ABC transporter, permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_2578 ABC transporter, permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D APE_1255.1 conserved hypothetical protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_1380.1 conserved hypothetical protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_1548.1 ABC transporter, ATP binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_1829 putative ABC transporter, ATP binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_1911.1 conserved hypothetical protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_1934.1 ABC transporter, ATP binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_2516 ABC transporter, ATP binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_2579.1 ABC transporter, ATP binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D APE_1253 conserved hypothetical protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D APE_1702 sufC; ATPase involved in Fe-S cluster formation SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D APE_1773.1 MatE efflux family protein K26939 norM; MATE family, multidrug efflux pump
D APE_2414.1 MatE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D APE_0955 voltage-gated potassium channel K10716 kch; voltage-gated potassium channel
D APE_0605.1 hypothetical protein K07114 yfbK; Ca-activated chloride channel homolog
D APE_0156.1 hypothetical protein K07244 K07244; mgtE-like transporter
D APE_0203.1 conserved hypothetical protein K07238 TC.ZIP; zinc transporter, ZIP family
D APE_1691 probable zinc transporter ZupT K07238 TC.ZIP; zinc transporter, ZIP family
D APE_0715.1 trkH; Trk system potassium uptake protein TrkH K03498 trkH; trk/ktr system potassium uptake protein
D APE_2456.1 trkA; Trk system potassium uptake protein TrkA K03499 trkA; trk/ktr system potassium uptake protein
D APE_1552 truncated ClcA homolog K03281 clcA; chloride channel protein, CIC family
D APE_2165 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D APE_2110 conserved hypothetical protein K09125 yhhQ; queuosine precursor transporter
D APE_2497 snatA; small neutral amino acid transporter K05595 marC; multiple antibiotic resistance protein
D APE_2490.1 FTR1 family protein K07243 FTR; high-affinity iron transporter
D APE_2162.1 cstA; carbon starvation protein A K06200 cstA; carbon starvation protein
D APE_1288.1 narG; nitrate reductase, alpha subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D APE_1294.1 narH; nitrate reductase, beta subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D APE_2563 probable arsenite oxidase small subunit precursor K08355 aoxA; arsenite oxidase small subunit [EC:1.20.2.1 1.20.9.1]
D APE_2556.1 probable arsenite oxidase large subunit K08356 aoxB; arsenite oxidase large subunit [EC:1.20.2.1 1.20.9.1]
D APE_0219 hypothetical protein K25503 cedB; DNA import protein CedB
D APE_0220 hypothetical protein K25504 cedA; DNA import protein CedA
D APE_0220a hypothetical protein K25505 cedA1; DNA import protein CedA1
D APE_2274 putative cytochrome C-type biogenesis protein K02198 ccmF; cytochrome c-type biogenesis protein CcmF
C 02044 Secretion system [BR:ape02044]
D APE_1905 flagellin homolog K07325 flaB; archaeal flagellin FlaB
D APE_1907 flagellin homolog K07325 flaB; archaeal flagellin FlaB
D APE_1899 hypothetical protein K07329 flaF; archaeal flagellar protein FlaF
D APE_1901 hypothetical protein K07330 flaG; archaeal flagellar protein FlaG
D APE_1898 archaeal flagellar protein H homolog K07331 flaH; archaeal flagellar protein FlaH
D APE_1896.1 archaeal flagellar protein I homolog K07332 flaI; archaeal flagellar protein FlaI
D APE_2208.1 protein kinase K07332 flaI; archaeal flagellar protein FlaI
D APE_1895.1 archaeal flagellar protein J homolog K07333 flaJ; archaeal flagellar protein FlaJ
D APE_2207.1 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ
D APE_0983.1 secY; preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D APE_1735 signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D APE_1081.1 probable signal recognition particle protein K03110 ftsY; fused signal recognition particle receptor
D APE_2176a secE; preprotein translocase SecE subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D APE_0772 signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19
D APE_2139a twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APE_2154a twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APE_2154.1 twin-arginine translocation protein, TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins
C 02022 Two-component system
C 02035 Bacterial motility proteins [BR:ape02035]
D APE_1905 flagellin homolog K07325 flaB; archaeal flagellin FlaB
D APE_1907 flagellin homolog K07325 flaB; archaeal flagellin FlaB
D APE_1899 hypothetical protein K07329 flaF; archaeal flagellar protein FlaF
D APE_1901 hypothetical protein K07330 flaG; archaeal flagellar protein FlaG
D APE_1898 archaeal flagellar protein H homolog K07331 flaH; archaeal flagellar protein FlaH
D APE_1896.1 archaeal flagellar protein I homolog K07332 flaI; archaeal flagellar protein FlaI
D APE_2208.1 protein kinase K07332 flaI; archaeal flagellar protein FlaI
D APE_1895.1 archaeal flagellar protein J homolog K07333 flaJ; archaeal flagellar protein FlaJ
D APE_2207.1 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:ape04812]
D APE_1771 conserved hypothetical protein K06990 MEMO1; MEMO1 family protein
C 04147 Exosome [BR:ape04147]
D APE_2458 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APE_0173.1 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D APE_0489 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D APE_0337.1 dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D APE_2278 thioredoxin peroxidase K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D APE_1844 tuf; elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D APE_1432 fusA; elongation factor 2 K03234 EEF2; elongation factor 2
D APE_0115.1 fen; flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D APE_1507.1 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D APE_1132a rps27ae; 30S ribosomal protein S27Ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D APE_1367 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_2474.1 cell division control protein 48, AAA family K13525 VCP; transitional endoplasmic reticulum ATPase
D APE_2495.1 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D APE_1307 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_1310 putative fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_2284.1 fadD; long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D APE_0929.1 putative 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2382.1 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_2384 conserved hypothetical protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D APE_0624.1 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D APE_0981.1 adkA; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D APE_1226 metC; cystathionine gamma-lyase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D APE_2601.1 NG,NG-dimethylarginine dimethylaminohydrolase K01482 DDAH; dimethylargininase [EC:3.5.3.18]
D APE_0306.1 putative carbohydrate kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D APE_2142.1 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APE_2300.1 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D APE_1669.1 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APE_0135 etfA; electron transfer flavoprotein alpha-subunit K03522 fixB; electron transfer flavoprotein alpha subunit
D APE_2419 etfA; electron transfer flavoprotein alpha-subunit K03522 fixB; electron transfer flavoprotein alpha subunit
D APE_1386.1 NADP-dependent glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D APE_1538.1 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:ape02048]
D APE_1240.1 cas1; putative CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D APE_1239a cas2; CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2
D APE_1232 cas3; CRISPR-associated helicase Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D APE_1231 CRISPR-associated protein K07475 cas3; CRISPR-associated endonuclease Cas3-HD [EC:3.1.-.-]
D APE_1241.1 putative CRISPR-associated protein K19085 csa1; CRISPR-associated protein Csa1
D APE_1237.1 putative CRISPR-associated DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D APE_1230 CRISPR-associated protein K19086 csa4; CRISPR-associated protein Csa4
D APE_1236.1 putative CRISPR-associated protein K19087 csa5; CRISPR-associated protein Csa5
D APE_1235 CRISPR-associated negative autoregulator K19075 cst2; CRISPR-associated protein Cst2
D APE_0373 hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D APE_1239.1 cas4; putative CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D APE_1234.1 CRISPR-associated protein K19089 cas5a_b_c; CRISPR-associated protein Cas5a/b/c
D APE_0872.1 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_2002 cytosine-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D APE_1495a conserved hypothetical protein K07746 parD1_3_4; antitoxin ParD1/3/4
D APE_2317.1 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APE_1102 conserved hypothetical protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:ape04090]
C 01504 Antimicrobial resistance genes
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ape00537]
D APE_0337.1 dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:ape03100]
D APE_tRNA09 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APE_tRNA18 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APE_tRNA37 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APE_tRNA04 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA22 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA30 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA38 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA47 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APE_tRNA14 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D APE_tRNA13 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D APE_tRNA42 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D APE_tRNA27 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D APE_tRNA45 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D APE_tRNA32 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D APE_tRNA41 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D APE_tRNA19 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APE_tRNA28 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APE_tRNA46 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APE_tRNA43 tRNA-His K14226 tRNA-His; tRNA His
D APE_tRNA23 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D APE_tRNA12 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA17 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA20 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA36 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA40 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APE_tRNA05 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APE_tRNA35 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APE_tRNA07 tRNA-Met K14230 tRNA-Met; tRNA Met
D APE_tRNA16 tRNA-Met K14230 tRNA-Met; tRNA Met
D APE_tRNA31 tRNA-Met K14230 tRNA-Met; tRNA Met
D APE_tRNA25 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D APE_tRNA02 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APE_tRNA10 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APE_tRNA33 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APE_tRNA03 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA11 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA24 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA34 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APE_tRNA01 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA06 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA26 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA29 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APE_tRNA15 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D APE_tRNA44 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D APE_tRNA08 tRNA-Val K14237 tRNA-Val; tRNA Val
D APE_tRNA21 tRNA-Val K14237 tRNA-Val; tRNA Val
D APE_tRNA39 tRNA-Val K14237 tRNA-Val; tRNA Val
D APE_rRNA05 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D APE_rRNA03 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D APE_rRNA01 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D APE_srpRNA01 RNA component of signal recognition particle K01983 ffs; SRP RNA
D APE_rnpRNA01 ribonuclease P RNA component K01978 rnpB; M1 RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D APE_2213 aldehyde dehydrogenase, small subunit K03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3]
D APE_2219 aldehyde dehydrogenase, middle subunit K03519 coxM; aerobic carbon-monoxide dehydrogenase medium subunit [EC:1.2.5.3]
D APE_2216.1 aldehyde dehydrogenase, large subunit K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3]
D APE_2421 FixC protein K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D APE_0086 thiol peroxidase K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D APE_2125.1 bcp; thiol peroxidase K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D APE_1458 mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1]
D APE_2598 conserved hypothetical protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D APE_1865.1 PflA homolog K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D APE_1535.1 PflX homolog K04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D APE_1011.1 pcm; protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D APE_0931 dphB; probable diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D APE_0698.1 dys; deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D APE_0621.1 probable farnesylgeranylglyceryl phosphate synthase K25920 E2.5.1.155; phosphoglycerol geranylfarnesyltransferase [EC:2.5.1.155]
D APE_0159 probable (S)-2,3-Di-O-farnesylgeranylglyceryl synthase K25921 E2.5.1.156; geranylfarnesylglycerol-phosphate geranylfarnesyltransferase [EC:2.5.1.156]
D APE_1526.1 putative CDP-alcohol phosphatidyltransferase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D APE_0026 hypothetical protein K22579 rph; rifampicin phosphotransferase [EC:2.7.9.6]
D APE_0028 hypothetical protein K22579 rph; rifampicin phosphotransferase [EC:2.7.9.6]
D APE_0680.1 conserved hypothetical protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D APE_2484.1 sixA; phosphohistidine phosphatase SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]
D APE_0423.1 putative deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D APE_0957 conserved hypothetical protein K07503 nucS; endonuclease [EC:3.1.-.-]
D APE_1501.1 ribonuclease UK114 K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D APE_0127 conserved hypothetical protein MoxR K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D APE_1035.1 conserved hypothetical protein K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D APE_1317 conserved hypothetical protein MoxR K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D APE_2338 conserved hypothetical protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D APE_0103.1 small heat shock protein K13933 mdcE; malonate decarboxylase gamma subunit [EC:4.1.1.87]
D APE_2362.1 conserved hypothetical protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D APE_0710.1 conserved hypothetical protein K01741 E4.2.99.18; DNA-(apurinic or apyrimidinic site) lyase [EC:4.2.99.18]
D APE_0511.1 rtcA; RNA 3'-terminal phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4]
D APE_1567.1 conserved hypothetical protein K07468 K07468; DNA/RNA ligase [EC:6.5.1.-]
C 99981 Carbohydrate metabolism
D APE_0454 conserved hypothetical protein K06206 sfsA; sugar fermentation stimulation protein A
D APE_0258.1 hypothetical protein K00782 lldG; L-lactate dehydrogenase complex protein LldG
C 99982 Energy metabolism
D APE_0104a.1 fdxA; ferredoxin K05337 fer; ferredoxin
D APE_0320.1 ferredoxin K05337 fer; ferredoxin
D APE_0134.1 etfB; electron transfer flavoprotein beta-subunit K03521 fixA; electron transfer flavoprotein beta subunit
D APE_2418.1 etfB; electron transfer flavoprotein beta-subunit K03521 fixA; electron transfer flavoprotein beta subunit
D APE_2460.1 FixX protein K03855 fixX; ferredoxin like protein
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
D APE_0178.1 mobB; molybdopterin-guanine dinucleotide biosynthesis protein MobB K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C 99988 Secondary metabolism
D APE_1871.1 conserved hypothetical protein AcaC K07068 DUF35; scaffold protein (connect acetoacetyl-CoA thiolase and HMG-CoA synthase)
C 99999 Others
D APE_0688 hypothetical protein K15975 K15975; glyoxalase family protein
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D APE_2011.1 putative HTH-type transcriptional regulator K03627 MBF1; putative transcription factor
D APE_1823 albA; DNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein
D APE_1832a.1 albA; DNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein
D APE_0525a small nucleolar RNP protein Sm K04796 RUXX; small nuclear ribonucleoprotein
D APE_0957a putative small nucleolar RNP protein Sm K04796 RUXX; small nuclear ribonucleoprotein
D APE_0974.1 conserved hypothetical protein K07744 K07744; transcriptional regulator
D APE_0469.1 conserved hypothetical protein K07745 K07745; transcriptional regulator
C 99974 Translation
D APE_0550 conserved hypothetical protein K07572 K07572; putative nucleotide binding protein
D APE_0181 putative exonuclease K07577 K07577; putative mRNA 3-end processing factor
D APE_2295.1 conserved hypothetical protein K07577 K07577; putative mRNA 3-end processing factor
D APE_0446 conserved hypothetical protein K07579 K07579; putative methylase
D APE_2480a conserved hypothetical protein K07580 K07580; Zn-ribbon RNA-binding protein
D APE_1451.1 conserved hypothetical protein K07581 K07581; RNA-binding protein
C 99975 Protein processing
D APE_2044.1 hypE; putative hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE
D APE_2020 conserved hypothetical protein K07398 K07398; conserved protein with predicted RNA binding PUA domain
D APE_2227 CoxF homolog K07402 xdhC; xanthine dehydrogenase accessory factor
D APE_2151.1 serine protease K07403 nfeD; membrane-bound serine protease (ClpP class)
C 99976 Replication and repair
D APE_0416.1 conserved hypothetical protein K07445 K07445; putative DNA methylase
D APE_0326.1 TATA box-binding protein-interacting protein TIP49 K07472 TIP49; TBP-interacting protein
D APE_2424 conserved hypothetical protein K07477 K07477; translin
C 99979 Viral proteins
C 99998 Others
D APE_1558 hypothetical protein K07504 K07504; predicted type IV restriction endonuclease
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D APE_0972.1 sodium/solute symporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D APE_1382 transporter, NCS1 nucleoside transporter family K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
C 99978 Cell growth
D APE_2485.1 conserved hypothetical protein K06384 spoIIM; stage II sporulation protein M
C 99993 Cell motility
C 99995 Signaling proteins
D APE_1790.1 conserved hypothetical protein K07176 K07176; putative serine/threonine protein kinase
D APE_1087b DNA-binding protein K06875 PDCD5; programmed cell death protein 5
C 99992 Structural proteins
C 99994 Others
D APE_0051 phosphate transport system protein PhoU K02039 phoU; phosphate transport system protein
D APE_1668 CutA homolog K03926 cutA; periplasmic divalent cation tolerance protein
B
B 09194 Poorly characterized
C 99996 General function prediction only
D APE_0462 conserved hypothetical protein K06865 K06865; ATPase
D APE_0675.1 tRNA-binding protein K06878 K06878; tRNA-binding protein
D APE_2500.1 hypothetical protein K06994 K06994; putative drug exporter of the RND superfamily
D APE_1703 sufB; FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D APE_1808 hypothetical protein K07038 K07038; inner membrane protein
D APE_1014.1 conserved hypothetical protein K07049 K07049; TatD-related deoxyribonuclease
D APE_0207 conserved hypothetical protein K07143 K07143; UPF0148 protein
D APE_0771.1 conserved hypothetical protein K08975 K08975; putative membrane protein
C 99997 Function unknown
D APE_0104.1 conserved hypothetical protein K06869 K06869; uncharacterized protein
D APE_2018.1 conserved hypothetical protein K06869 K06869; uncharacterized protein
D APE_0428.1 hypothetical protein K06870 K06870; uncharacterized protein
D APE_2279.1 conserved hypothetical protein K06870 K06870; uncharacterized protein
D APE_1281 hypothetical protein K06885 K06885; uncharacterized protein
D APE_2533.1 conserved hypothetical protein K06888 K06888; uncharacterized protein
D APE_1244.1 hypothetical protein K06889 K06889; uncharacterized protein
D APE_0415 conserved hypothetical protein K06922 K06922; uncharacterized protein
D APE_1660.1 conserved hypothetical protein K06929 K06929; uncharacterized protein
D APE_1509.1 conserved hypothetical protein K06934 K06934; uncharacterized protein
D APE_1874.1 conserved hypothetical protein K06935 K06935; uncharacterized protein
D APE_1861.1 conserved hypothetical protein K06953 K06953; uncharacterized protein
D APE_2448 BtpA homolog K06971 K06971; uncharacterized protein
D APE_0900.1 conserved hypothetical protein K06975 K06975; uncharacterized protein
D APE_0964.1 conserved hypothetical protein K06983 K06983; uncharacterized protein
D APE_0500.1 conserved hypothetical protein K07022 K07022; uncharacterized protein
D APE_1706 sufD; FeS assembly protein SufD K07033 K07033; uncharacterized protein
D APE_0522.1 putative exonuclease K07041 K07041; uncharacterized protein
D APE_2240 putative amidohydrolase K07045 K07045; uncharacterized protein
D APE_2502.1 conserved hypothetical protein K07045 K07045; uncharacterized protein
D APE_1209b conserved hypothetical protein K07064 K07064; uncharacterized protein
D APE_0213.1 conserved hypothetical protein K07073 K07073; uncharacterized protein
D APE_2136.1 TRAP transporter, solute-binding component K07080 K07080; uncharacterized protein
D APE_2545.1 TRAP transporter, solute-binding component K07080 K07080; uncharacterized protein
D APE_0183.1 conserved hypothetical protein K07090 K07090; uncharacterized protein
D APE_1196.1 conserved hypothetical protein K07090 K07090; uncharacterized protein
D APE_0682.1 conserved hypothetical protein K07095 K07095; uncharacterized protein
D APE_2283.1 conserved hypothetical protein K07096 K07096; uncharacterized protein
D APE_0124 conserved hypothetical protein K07097 K07097; uncharacterized protein
D APE_0490.1 purine phosphoribosyltransferase K07101 K07101; uncharacterized protein
D APE_2071.1 purine phosphoribosyltransferase K07101 K07101; uncharacterized protein
D APE_0776 conserved hypothetical protein K07108 K07108; uncharacterized protein
D APE_2272.1 conserved hypothetical protein K07128 K07128; uncharacterized protein
D APE_0644.1 conserved hypothetical protein K07129 K07129; uncharacterized protein
D APE_2365.1 hypothetical protein K07158 K07158; uncharacterized protein
D APE_2221.1 CoxE homolog K07161 K07161; uncharacterized protein
D APE_1824 conserved hypothetical protein K09003 K09003; uncharacterized protein
D APE_0476.1 conserved hypothetical protein K09120 K09120; uncharacterized protein
D APE_2177.1 conserved hypothetical protein K09122 K09122; uncharacterized protein
D APE_2289.1 conserved hypothetical protein K09129 K09129; uncharacterized protein
D APE_0182.1 conserved hypothetical protein K09131 K09131; uncharacterized protein
D APE_1056.1 conserved hypothetical protein K09141 K09141; uncharacterized protein
D APE_0097.1 hypothetical protein K09147 K09147; uncharacterized protein
D APE_0132.1 conserved hypothetical protein K09148 K09148; uncharacterized protein
D APE_1868.1 conserved hypothetical protein K09149 K09149; uncharacterized protein
D APE_1599.1 conserved hypothetical protein K09150 K09150; uncharacterized protein
D APE_2446 conserved hypothetical protein K09157 K09157; uncharacterized protein
D APE_1666 conserved hypothetical protein K09163 K09163; uncharacterized protein
D APE_2225.1 CoxG homolog K09386 K09386; uncharacterized protein
D APE_0939 hypothetical protein K09715 K09715; uncharacterized protein
D APE_1943.1 hypothetical protein K09717 K09717; uncharacterized protein
D APE_2336a conserved hypothetical protein K09721 K09721; uncharacterized protein
D APE_0680a.1 conserved hypothetical protein K09732 K09732; uncharacterized protein
D APE_1751 conserved hypothetical protein K09736 K09736; uncharacterized protein
D APE_2195 hypothetical protein K09737 K09737; uncharacterized protein
D APE_1009.1 conserved hypothetical protein K09738 K09738; uncharacterized protein
D APE_0444.1 conserved hypothetical protein K09742 K09742; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: January 20, 2025