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Mitochondrial Biogenesis - Caenorhabditis elegans (nematode)
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
D KEF34_p10 ND1; NADH dehydrogenase subunit 1 K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
D KEF34_p08 ND2; NADH dehydrogenase subunit 2 K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
D KEF34_p02 ND3; NADH dehydrogenase subunit 3 K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
D KEF34_p05 ND4; NADH dehydrogenase subunit 4 K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
D KEF34_p11 ND4L; NADH dehydrogenase subunit 4L K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
D KEF34_p01 ND5; NADH dehydrogenase subunit 5 K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
D KEF34_p12 ND6; NADH dehydrogenase subunit 6 K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
C Mitochondrial respiratory chain complex III
D KEF34_p07 CYTB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
C Cytochrome c oxidase
D KEF34_p04 COX1; cytochrome c oxidase subunit I K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
D KEF34_p03 COX2; cytochrome c oxidase subunit II K02261 COX2; cytochrome c oxidase subunit 2
D KEF34_p06 COX3; cytochrome c oxidase subunit III K02262 COX3; cytochrome c oxidase subunit 3
C F-type ATPase
D KEF34_p09 ATP6; ATP synthase F0 subunit 6 K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D CELE_Y105E8A.23 rpom-1; DNA-directed RNA polymerase K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
D CELE_F45E4.9 hmg-5; HMG box-containing protein 5 K11830 TFAM; transcription factor A, mitochondrial
D CELE_T03F1.7 tfbm-1; Dimethyladenosine transferase 1, mitochondrial K15266 TFB1M; dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-]
C Mitochondrial translation factors
D CELE_F46B6.6 F46B6.6; Tr-type G domain-containing protein K02519 infB; translation initiation factor IF-2
D CELE_F55C5.5 tsfm-1; Elongation factor Ts, mitochondrial K02357 tsf; elongation factor Ts
D CELE_C43E11.4 tufm-2; Tr-type G domain-containing protein K02358 tuf; elongation factor Tu
D CELE_Y71H2AM.23 tufm-1; Elongation factor Tu, mitochondrial K02358 tuf; elongation factor Tu
D CELE_F29C12.4 gfm-1; Elongation factor G, mitochondrial K02355 fusA; elongation factor G
D CELE_Y119D3B.14 Y119D3B.14; Tr-type G domain-containing protein K02355 fusA; elongation factor G
D CELE_C50F4.12 C50F4.12; Transcription termination factor 3, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D CELE_K11D2.5 mter-4; Mitochondrial transcription termination factor family protein K15031 MTERF; mitochondrial transcription termination factor family protein
D CELE_ZK1236.1 ZK1236.1; Translation factor GUF1 homolog, mitochondrial K21594 GUF1; translation factor GUF1, mitochondrial [EC:3.6.5.-]
C RNase MRP
D CELE_C05D11.9 popl-1; Ribonucleases P/MRP protein subunit popl-1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D CELE_C15C6.4 popl-4; Ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D CELE_Y66A7A.2 popl-5; Ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D CELE_H35B03.2 H35B03.2; Ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D CELE_Y62E10A.24 Y62E10A.24; Ribonuclease P protein subunit p20 K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D CELE_ZK632.14 ZK632.14; DNA/RNA-binding protein Alba-like domain-containing protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
D CELE_F46F11.10 trmt-10C.1; RNA (guanine-9-)-methyltransferase domain-containing protein 1 K17654 TRMT10C; mitochondrial ribonuclease P protein 1 [EC:2.1.1.-]
D CELE_F01G4.2 ard-1; 3-hydroxyacyl-CoA dehydrogenase K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
C Other mitochondrial DNA transcription and translation factors
D CELE_Y110A7A.19 let-630; Small ribosomal subunit protein mS39 K17659 PTCD3; pentatricopeptide repeat domain-containing protein 3
D CELE_C35D10.5 C35D10.5; Ubiquinol-cytochrome c chaperone domain-containing protein K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D CELE_C30F12.2 C30F12.2; ATPase N2B K18798 AFG1; peroxisome-assembly ATPase [EC:3.6.4.7]
D CELE_C08F8.2 C08F8.2; ATP-dependent RNA helicase SUV3 homolog, mitochondrial K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D CELE_Y53F4B.39 Y53F4B.39; Beta-lactamase-like protein 2 homolog K16639 LACTB2; endoribonuclease LACTB2 [EC:3.1.27.-]
D CELE_K01H12.2 ant-1.3; ADP/ATP translocase K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D CELE_T01B11.4 ant-1.4; ADP/ATP translocase K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D CELE_F25B4.7 F25B4.7; ADP/ATP translocase K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D CELE_W02D3.6 ant-1.2; ADP/ATP translocase K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D CELE_T27E9.1 ant-1.1; ADP/ATP translocase K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D CELE_C47E12.2 C47E12.2; ADP/ATP translocase K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D CELE_R07E3.4 R07E3.4; ADP/ATP translocase K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D CELE_W02B12.9 mfn-1; Mitoferrin K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D CELE_E02H1.2 eral-1; GTPase Era, mitochondrial K03595 era; GTPase
D CELE_Y105E8A.19 yars-1; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CELE_K08F11.4 yars-2; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CELE_R74.1 lars-1; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CELE_ZK524.3 lars-2; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CELE_F10C2.6 dars-2; Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D CELE_T10F2.1 gars-1; Glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D CELE_C29H12.1 rars-2; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CELE_F26F4.10 rars-1; putative arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CELE_Y41D4A.6 Y41D4A.6; Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D CELE_Y66D12A.7 Y66D12A.7; Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D CELE_R17.2 pde-12; Endonuclease/exonuclease/phosphatase domain-containing protein K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
D CELE_Y67D2.4 mtg-1; CP-type G domain-containing protein K19828 MTG1; mitochondrial GTPase 1
D CELE_Y48E1B.2 noa-1; G domain-containing protein K19832 NOA1; nitric oxide-associated protein 1
D CELE_Y39G10AR.21 nsun-4; 5-methylcytosine rRNA methyltransferase nsun-4 K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]
D CELE_W09G3.7 W09G3.7; Williams-Beuren syndrome chromosomal region 16 protein K23495 RCC1L; RCC1-like G exchanging factor-like protein
D CELE_Y43B11AR.3 Y43B11AR.3; TruB_N domain-containing protein K23497 TRUB2; mitochondrial mRNA pseudouridine synthase TRUB2 [EC:5.4.99.-]
D CELE_ZK1010.2 ZK1010.2; DUF155 domain-containing protein K23499 RMND1; required for meiotic nuclear division protein 1
D CELE_C27H6.8 C27H6.8; MYG1 protein C27H6.8 K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D CELE_Y57A10A.15 polg-1; Mitochondrial DNA polymerase catalytic subunit K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
C Mitochondrial DNA maintenance factors
D CELE_C41D11.8 cps-6; Endonuclease G, mitochondrial K01173 ENDOG; endonuclease G, mitochondrial
D CELE_C27H6.9 C27H6.9; Mitochondrial genome maintenance exonuclease 1 K19465 MGME1; mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]
D CELE_F46G11.1 twnk-1; SF4 helicase domain-containing protein K17680 PEO1; twinkle protein [EC:5.6.2.3]
D CELE_Y18H1A.6 pif-1; ATP-dependent DNA helicase K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
C Other Mitochondrial DNA replication factors
D CELE_F54B3.3 atad-3; ATPase family AAA domain-containing protein 3 K17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A/B
D CELE_Y48A5A.3 Y48A5A.3; Ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D CELE_T05C3.5 dnj-19; DNaJ domain (prokaryotic heat shock protein) K09503 DNAJA2; DnaJ homolog subfamily A member 2
D CELE_K08F11.5 miro-1; Mitochondrial Rho GTPase 1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D CELE_F26D10.3 hsp-1; Heat shock protein hsp-1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CELE_F44E5.4 F44E5.4; Heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CELE_C12C8.1 hsp-70; Heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CELE_F44E5.5 F44E5.5; Heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CELE_F11F1.1 F11F1.1; DUF148 domain-containing protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D CELE_C56C10.10 aipr-1; TPR_REGION domain-containing protein K17767 AIP; AH receptor-interacting protein
B Outer membrane
C Transporter outer membrane (TOM) complex
D CELE_C18E9.6 tomm-40; Mitochondrial import receptor subunit TOM40 homolog K11518 TOM40; mitochondrial import receptor subunit TOM40
D CELE_W10D9.5 tomm-22; Mitochondrial import receptor subunit TOM22 homolog K17769 TOM22; mitochondrial import receptor subunit TOM22
D CELE_F23H12.2 tomm-20; Mitochondrial import receptor subunit TOM20 homolog K17770 TOM20; mitochondrial import receptor subunit TOM20
D CELE_ZK652.2 tomm-7; Mitochondrial import receptor subunit TOM7 homolog K17771 TOM7; mitochondrial import receptor subunit TOM7
C TOB/SAM complex
D CELE_C34E10.1 gop-3; SAM50-like protein gop-3 K07277 SAM50; outer membrane protein insertion porin family
C Porin
D CELE_R05G6.7 vdac-1; putative voltage-dependent anion-selective channel K15040 VDAC2; voltage-dependent anion channel protein 2
C ERMES complex
C Other outer membrane factor
D CELE_F39B2.11 mtx-1; Metaxin-1 homolog K17776 MTX; metaxin
D CELE_ZC97.1 mtx-2; Metaxin-2 homolog K17776 MTX; metaxin
D CELE_F56A11.5 F56A11.5; MOSC domain-containing protein K27318 MTARC; mitochondrial amidoxime-reducing component [EC:1.7.-.-]
D CELE_F53E10.1 F53E10.1; MOSC domain-containing protein K27318 MTARC; mitochondrial amidoxime-reducing component [EC:1.7.-.-]
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D CELE_C06G3.11 tin-9.1; Mitochondrial import inner membrane translocase subunit Tim9 K17777 TIM9; mitochondrial import inner membrane translocase subunit TIM9
D CELE_Y66D12A.22 tin-10; Mitochondrial import inner membrane translocase subunit Tim10 K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
C TIM8/13 complex
D CELE_Y39A3CR.4 ddp-1; Mitochondrial import inner membrane translocase subunit Tim8 K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D CELE_DY3.1 tin-13; Mitochondrial import inner membrane translocase subunit tim-13 K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D CELE_ZK616.3 ZK616.3; CHCH domain-containing protein K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D CELE_F11C1.1 F11C1.1; CHCH domain-containing protein K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D CELE_F42H10.2 F42H10.2; Uncharacterized protein K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D CELE_F56C11.3 F56C11.3; Sulfhydryl oxidase K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
D CELE_F54A3.5 F54A3.5; MICOS complex subunit Mic10 K17784 MICOS10; MICOS complex subunit MIC10
D CELE_T14G11.3 immt-1; MICOS complex subunit MIC60-1 K17785 IMMT; MICOS complex subunit MIC60
D CELE_W06H3.1 immt-2; MICOS complex subunit MIC60-2 K17785 IMMT; MICOS complex subunit MIC60
D CELE_W04C9.2 W04C9.2; MICOS complex subunit MIC13 K24624 MICOS13; MICOS complex subunit MIC13
D CELE_K02F3.10 moma-1; MICOS complex subunit MIC27 K24626 APOOL; MICOS complex subunit MIC27
C MICOS complex (yeast)
D CELE_F54A3.5 F54A3.5; MICOS complex subunit Mic10 K17784 MICOS10; MICOS complex subunit MIC10
D CELE_T14G11.3 immt-1; MICOS complex subunit MIC60-1 K17785 IMMT; MICOS complex subunit MIC60
D CELE_W06H3.1 immt-2; MICOS complex subunit MIC60-2 K17785 IMMT; MICOS complex subunit MIC60
C TIM22 complex
D CELE_C47G2.3 C47G2.3; Mitochondrial import inner membrane translocase subunit tim-22 K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
C TIM23 complex
D CELE_F15D3.7 timm-23; Mitochondrial import inner membrane translocase subunit TIM23 K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
D CELE_E04A4.5 timm-17B.1; putative mitochondrial import inner membrane translocase subunit tim-17B.1 K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D CELE_F56B3.11 F56B3.11; Mitochondrial import inner membrane translocase subunit Tim21 K17796 TIM21; mitochondrial import inner membrane translocase subunit TIM21
D CELE_T21C9.12 scpl-4; Mitochondrial import inner membrane translocase subunit TIM50 K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
D CELE_K02B2.3 mcu-1; Calcium uniporter protein, mitochondrial K20858 MCU; calcium uniporter protein, mitochondrial
D CELE_Y67H2A.4 micu-1; Calcium uptake protein 1 homolog, mitochondrial K22827 MICU1; calcium uptake protein 1, mitochondrial
D CELE_F20D1.10 emre-1; Essential MCU regulator, mitochondrial K22830 SMDT1; essential MCU regulator, mitochondrial
C Other inner membrane factors
D CELE_F58G11.1 letm-1; Mitochondrial proton/calcium exchanger protein K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D CELE_C24H11.6 immp-1; Peptidase S26 domain-containing protein K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
D CELE_Y55F3AM.8 immp-2; Peptidase S26 domain-containing protein K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
D CELE_R07E5.13 mpc-1; putative mitochondrial pyruvate carrier 1 K22138 MPC1; mitochondrial pyruvate carrier 1
D CELE_F53F10.3 mpc-2; putative mitochondrial pyruvate carrier 2 K22139 MPC2; mitochondrial pyruvate carrier 2
B Matrix
C MMC/PAM proteins
D CELE_T09B4.9 tin-44; putative mitochondrial import inner membrane translocase subunit tin-44 K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D CELE_C37H5.8 hsp-6; Heat shock protein hsp-6 K04043 dnaK; molecular chaperone DnaK
D CELE_C34C12.8 C34C12.8; GrpE protein homolog, mitochondrial K03687 GRPE; molecular chaperone GrpE
D CELE_T19B4.4 dnj-21; Mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
D CELE_F45G2.8 F45G2.8; Mitochondrial import inner membrane translocase subunit tim-16 K17805 PAM16; mitochondrial import inner membrane translocase subunit TIM16
C Other matrix factors
D CELE_Y71G12B.24 mppa-1; Mitochondrial-processing peptidase subunit alpha K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D CELE_ZC410.2 mppb-1; Mitochondrial-processing peptidase subunit beta K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D CELE_F56D2.1 ucr-1; Cytochrome b-c1 complex subunit 1, mitochondrial K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D CELE_Y67H2A.7 Y67H2A.7; Peptidase M3A/M3B catalytic domain-containing protein K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D CELE_Y22D7AL.5 hsp-60; Chaperonin homolog Hsp-60, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D CELE_Y22D7AL.10 Y22D7AL.10; 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
D CELE_F22B7.5 dnj-10; DnaJ homolog dnj-10 K09504 DNAJA3; DnaJ homolog subfamily A member 3
D CELE_Y71F9B.2 Y71F9B.2; Phosphatidate cytidylyltransferase, mitochondrial K17807 TAM41; mitochondrial translocator assembly and maintenance protein 41
D CELE_F53A3.7 F53A3.7; DNL-type domain-containing protein K17808 ZIM17; mitochondrial protein import protein ZIM17
D CELE_C33A12.7 ethe-1; Metallo-beta-lactamase domain-containing protein K17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]
D CELE_ZK652.10 tag-307; ApaG domain-containing protein K17809 POLDIP2; polymerase delta-interacting protein 2
#
AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D CELE_Y41C4A.4 crh-1; CREB homolog crh-1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D CELE_F29C12.4 gfm-1; Elongation factor G, mitochondrial K02355 fusA; elongation factor G
D CELE_Y119D3B.14 Y119D3B.14; Tr-type G domain-containing protein K02355 fusA; elongation factor G
D CELE_F45E4.9 hmg-5; HMG box-containing protein 5 K11830 TFAM; transcription factor A, mitochondrial
C Nuclear respiratory factors
D CELE_T19E7.2 skn-1; Protein skinhead-1 K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
D CELE_K11G9.6 mtl-1; Metallothionein-1 K14739 MT1_2; metallothionein 1/2
C Coactivators
D CELE_R10E11.1 cbp-1; Protein cbp-1 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C Proteins involved in Fe-S cluster biogenesis
D CELE_B0205.6 nfs-1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D CELE_Y45F10D.4 iscu-1; NIF system FeS cluster assembly NifU N-terminal domain-containing protein K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D CELE_F59G1.7 frh-1; Frataxin, mitochondrial K19054 FXN; frataxin [EC:1.16.3.1]
D CELE_Y73F8A.27 fdx-2; 2Fe-2S ferredoxin-type domain-containing protein K22071 FDX2; ferredoxin-2, mitochondrial
D CELE_Y62E10A.6 Y62E10A.6; NADPH:adrenodoxin oxidoreductase, mitochondrial K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D CELE_C37H5.8 hsp-6; Heat shock protein hsp-6 K04043 dnaK; molecular chaperone DnaK
D CELE_K08D10.2 dnj-15; J domain-containing protein K04082 hscB; molecular chaperone HscB
D CELE_Y49E10.2 glrx-5; Glutaredoxin domain-containing protein K07390 grxD; monothiol glutaredoxin
D CELE_Y39B6A.3 Y39B6A.3; Iron-sulfur cluster assembly 1 homolog, mitochondrial K22063 ISCA1; iron-sulfur cluster assembly 1
D CELE_Y54G11A.9 Y54G11A.9; FeS cluster biogenesis domain-containing protein K22072 ISCA2; iron-sulfur cluster assembly 2
D CELE_F39H2.3 F39H2.3; Aminomethyltransferase folate-binding domain-containing protein K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D CELE_R10H10.1 nfu-1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D CELE_K11H12.1 K11H12.1; Putative bolA-like protein K11H12.1 K22066 BOLA1; BolA-like protein 1
D CELE_Y105E8A.11 Y105E8A.11; BolA-like protein 3 K22075 BOLA3; BolA-like protein 3
D CELE_AH6.2 sfxn-1.1; Sideroflexin-1.1 K23500 SFXN1_3; sideroflexin-1/3
D CELE_C47D12.3 sfxn-1.4; Sidoreflexin K23500 SFXN1_3; sideroflexin-1/3
D CELE_F37H8.4 sfxn-1.2; Sidoreflexin K23500 SFXN1_3; sideroflexin-1/3
D CELE_T04F8.1 sfxn-1.5; Sidoreflexin K23500 SFXN1_3; sideroflexin-1/3
D CELE_Y6E2A.9 sfxn-1.3; Sidoreflexin K23500 SFXN1_3; sideroflexin-1/3
D CELE_C14F5.4 sfxn-2; Sidoreflexin K23501 SFXN2; sideroflexin-2
D CELE_C41C4.10 sfxn-5; Sideroflexin-5 K23503 SFXN5; sideroflexin-5
C Other regulator of mitochondrial biogenesis
D CELE_Y46G5A.17 cpt-1; carnitine O-palmitoyltransferase K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D CELE_W03F9.4 W03F9.4; Choline/carnitine acyltransferase domain-containing protein K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D CELE_ZK836.2 ogdh-2; putative 2-oxoadipate dehydrogenase complex component E1 homolog K15791 DHKTD1; 2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
D CELE_C46A5.9 hcf-1; Host cell factor homolog hcf-1 K27390 HCFC2; host cell factor 2
D CELE_T01C8.1 aak-2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D CELE_PAR2.3 aak-1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D CELE_Y75B8A.4 lonp-2; Lon protease homolog 2, peroxisomal K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D CELE_C34B2.6 lonp-1; Lon protease homolog, mitochondrial K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D CELE_R11A8.4 sir-2.1; NAD-dependent protein deacetylase sir-2.1 K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
D CELE_F35H10.6 F35H10.6; Spindle and kinetochore-associated protein 2 K26537 UXT; protein UXT
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
D CELE_C50B8.3 nuaf-1; putative complex I intermediate-associated protein 30, mitochondrial K18159 NDUFAF1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1
D CELE_Y94H6A.8 ndua-12; putative NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 K18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
D CELE_Y116A8C.30 Y116A8C.30; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 K18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
D CELE_R07H5.3 nuaf-3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 K09008 NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
D CELE_K09E4.3 K09E4.3; Arginine-hydroxylase NDUFAF5, mitochondrial K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D CELE_B0334.5 B0334.5; Phytoene synthase K18163 NDUFAF6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6
D CELE_ZK1128.1 ZK1128.1; Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D CELE_C34E10.12 C34E10.12; CX9C domain-containing protein K24726 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8
D CELE_Y17G9B.5 Y17G9B.5; Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
D CELE_M04B2.4 M04B2.4; FAD-dependent oxidoreductase domain-containing protein 1 K18166 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1
D CELE_F56H1.6 rad-8; Reticulon-4-interacting protein 1, mitochondrial K23164 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial
D CELE_Y38F2AR.3 Y38F2AR.3; Complex I assembly factor TIMMDC1, mitochondrial K23505 TIMMDC1; complex I assembly factor TIMMDC1
C Complex-II assembly factors
C Complex-III assembly factors
D CELE_F54C9.6 bcs-1; Mitochondrial chaperone BCS1 K08900 BCS1; mitochondrial chaperone BCS1
D CELE_Y54G11A.8 ddl-3; TPR_REGION domain-containing protein K18169 TTC19; tetratricopeptide repeat protein 19, mitochondrial
D CELE_C35D10.5 C35D10.5; Ubiquinol-cytochrome c chaperone domain-containing protein K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D CELE_Y48A5A.3 Y48A5A.3; Ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
D CELE_B0205.12 B0205.12; YtxH domain-containing protein K27319 STMP1; short transmembrane mitochondrial protein 1
C Complex-IV assembly factors
D CELE_F01F1.2 F01F1.2; COX assembly mitochondrial protein K18171 CMC1; COX assembly mitochondrial protein 1
D CELE_C35D10.17 C35D10.17; COX assembly mitochondrial protein 2 homolog K18172 CMC2; COX assembly mitochondrial protein 2
D CELE_Y18D10A.16 coa-5; Cytochrome c oxidase assembly factor 5 K18178 COA5; cytochrome c oxidase assembly factor 5
D CELE_ZC434.7 coa-6; Cytochrome c oxidase assembly factor 6 homolog K18179 COA6; cytochrome c oxidase assembly factor 6
D CELE_ZK20.4 coa-7; Cytochrome c oxidase assembly factor 7 homolog K18180 COA7; cytochrome c oxidase assembly factor 7
D CELE_Y46G5A.2 cox-10; Heme O synthase K02257 COX10; heme o synthase [EC:2.5.1.141]
D CELE_JC8.5 cox-11; Cytochrome c oxidase assembly protein COX11, mitochondrial K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D CELE_T06D8.5 cox-15; EOG090X04TT K02259 COX15; heme a synthase [EC:1.17.99.9]
D CELE_F40G9.2 cox-17; Cytochrome c oxidase copper chaperone K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D CELE_Y55F3AR.1 cox-18; Cytochrome OXidase assembly protein K17797 COX18; mitochondrial inner membrane protein COX18
D CELE_F45H11.5 cox-19; CHCH domain-containing protein K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D CELE_Y53F4B.14 Y53F4B.14; Protein PET100 homolog, mitochondrial K18186 PET100; protein PET100, animal type
D CELE_C01A2.3 oxa-1; Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D CELE_H06I04.2 sft-1; SURF1-like protein K14998 SURF1; surfeit locus 1 family protein
D CELE_C01F1.2 sco-1; Thioredoxin domain-containing protein K07152 SCO1; protein SCO1
D CELE_Y50D7A.9 taco-1; Transcriptional regulatory protein K18189 TACO1; translational activator of cytochrome c oxidase 1
D CELE_C04E6.11 lrpr-1; Leucine Rich Pentatricopeptide Repeat homolog K17964 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial
D CELE_Y39B6A.34 Y39B6A.34; COA8 family protein Y39B6A.34, mitochondrial K23506 APOPT1; apoptogenic protein 1
D CELE_B0205.12 B0205.12; YtxH domain-containing protein K27319 STMP1; short transmembrane mitochondrial protein 1
C Complex-V assembly factors
D CELE_Y116A8C.27 Y116A8C.27; ATP synthase mitochondrial F1 complex assembly factor 2 K07556 ATPeAF2; ATP synthase mitochondrial F1 complex assembly factor 2
D CELE_F32D8.5 F32D8.5; Transmembrane protein 70 homolog, mitochondrial K17966 TMEM70; transmembrane protein 70, mitochondrial
B Mitochondrial dynamics
C Fission and Fusion factors
D CELE_ZK1248.14 fzo-1; Transmembrane GTPase fzo-1 K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D CELE_D2013.5 eat-3; Dynamin-like GTPase OPA1, mitochondrial K17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]
D CELE_T09A5.7 mdmh-35; MitochonDrial interMembrane space protein Homolog K17968 TRIAP1; TRIAP1/MDM35 family protein
D CELE_Y54E10A.14 rom-5; rhomboid protease K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D CELE_T12E12.4 drp-1; Dynamin-1-like protein drp-1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D CELE_F13B9.8 fis-2; FIS1-related protein fis-2 K17969 FIS1; mitochondrial fission 1 protein
D CELE_K12C11.2 smo-1; Small ubiquitin-related modifier K12160 SUMO; small ubiquitin-related modifier
D CELE_F35A5.8 F35A5.8; SH3 domain-containing GRB2-like protein B1 K11248 SH3GLB1; endophilin-B1
D CELE_F43E2.7 mtch-1; Mitochondrial carrier K17885 MTCH; mitochondrial carrier
D CELE_F55F8.6 mff-2; Mitochondrial fission factor K22076 MFF; mitochondrial fission factor
C Actin cytoskeleton organization
D CELE_M03F4.2 act-4; Actin-4 K05692 ACTB_G1; actin beta/gamma 1
D CELE_T04C12.4 act-3; Actin-3 K05692 ACTB_G1; actin beta/gamma 1
D CELE_T04C12.6 act-1; Actin-1 K05692 ACTB_G1; actin beta/gamma 1
D CELE_T04C12.5 act-2; Actin-2 K05692 ACTB_G1; actin beta/gamma 1
D CELE_T25C8.2 act-5; Actin K05692 ACTB_G1; actin beta/gamma 1
D CELE_Y97E10AL.3 natb-1; N-alpha-acetyltransferase 20 K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
D CELE_R13F6.10 cra-1; N-terminal acetyltransferase B complex subunit NAA25 homolog K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D CELE_Y37E3.9 phb-1; Mitochondrial prohibitin complex protein 1 K17080 PHB1; prohibitin 1
D CELE_T24H7.1 phb-2; Mitochondrial prohibitin complex protein 2 K17081 PHB2; prohibitin 2
C Retention of mitochondria
D CELE_T12E12.4 drp-1; Dynamin-1-like protein drp-1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D CELE_F36D4.3 hum-2; Myosin motor domain-containing protein K10357 MYO5; myosin V
C Morphogenesis factors
D CELE_K08F11.5 miro-1; Mitochondrial Rho GTPase 1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D CELE_T14G11.3 immt-1; MICOS complex subunit MIC60-1 K17785 IMMT; MICOS complex subunit MIC60
D CELE_W06H3.1 immt-2; MICOS complex subunit MIC60-2 K17785 IMMT; MICOS complex subunit MIC60
D CELE_T13C5.6 T13C5.6; Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein K17981 MTFP1; mitochondrial fission process protein 1
D CELE_T13C5.8 mtp-18; Mitochondrial fission process protein 1 K17981 MTFP1; mitochondrial fission process protein 1
D CELE_C14A4.2 dap-3; Small ribosomal subunit protein mS29 K17408 DAP3; small subunit ribosomal protein S29
D CELE_Y92H12A.2 Y92H12A.2; E3 ubiquitin-protein ligase K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
B Mitophagy factors
C Autophagy-related proteins
D CELE_M03A8.2 atg-2; Autophagy-related protein 2 K17906 ATG2; autophagy-related protein 2
D CELE_Y55F3AM.4 atg-3; Ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D CELE_Y87G2A.3 atg-4.1; Cysteine protease atg-4.1 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D CELE_ZK792.8 atg-4.2; Cysteine protease atg-4.2 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D CELE_Y71G12B.12 atg-5; Autophagy-related protein 5 K08339 ATG5; autophagy-related protein 5
D CELE_T19E7.3 bec-1; Beclin homolog K08334 BECN; beclin
D CELE_M7.5 atg-7; Ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D CELE_C32D5.9 lgg-1; Protein lgg-1 K08341 GABARAP; GABA(A) receptor-associated protein
D CELE_T22H9.2 atg-9; Autophagy-related protein 9 K17907 ATG9; autophagy-related protein 9
D CELE_D2085.2 atg-10; Ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D CELE_B0336.8 lgg-3; Ubiquitin-like protein atg-12 K08336 ATG12; ubiquitin-like protein ATG12
D CELE_Y106G6A.2 epg-8; MRG domain-containing protein K17889 ATG14L; beclin 1-associated autophagy-related key regulator
D CELE_F02E8.5 atg-16.1; Autophagic-related protein 16.1 K17890 ATG16L1; autophagy-related protein 16-1
D CELE_K06A1.5 atg-16.2; Autophagic-related protein 16.2 K17890 ATG16L1; autophagy-related protein 16-1
D CELE_F41E6.13 atg-18; Autophagy-related protein 18 K17908 WIPI1_2; autophagy-related protein 18
C Parkin-dependent mechanism factors
D CELE_K08E3.7 pdr-1; RBR-type E3 ubiquitin transferase K04556 PARK2; parkin [EC:2.3.2.31]
D CELE_C34E10.3 gop-1; Protein CLEC16A homolog K19513 CLEC16A; protein CLEC16A
D CELE_EEED8.9 pink-1; Serine/threonine-protein kinase pink-1, mitochondrial K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
D CELE_Y54E10A.14 rom-5; rhomboid protease K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
C Parkin-independent mechanism factors
D CELE_D2007.5 atg-13; Autophagy-related protein 13 homolog K08331 ATG13; autophagy-related protein 13
D CELE_Y60A3A.1 unc-51; Serine/threonine-protein kinase unc-51 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D CELE_T08A9.1 epg-7; Autophagy-related protein 11 C-terminal domain-containing protein K17589 RB1CC1; RB1-inducible coiled-coil protein 1
D CELE_C47E8.5 hsp-90; Heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
D CELE_W08F4.8 cdc-37; Hsp90 chaperone protein kinase-targeting subunit K09554 CDC37; cell division cycle protein 37
D CELE_T06D8.7 fndc-1; FUN14 domain-containing protein fndc-1 K17986 FUNDC1; FUN14 domain-containing protein 1
C Other mitophagy factors
D CELE_T01C8.1 aak-2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D CELE_PAR2.3 aak-1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D CELE_ZK593.6 lgg-2; Protein lgg-2 K10435 MAP1LC; microtubule-associated protein 1 light chain
D CELE_T01H3.2 T01H3.2; Peroxin/Ferlin domain-containing protein K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
D CELE_Y65B4A.8 Y65B4A.8; Cytidyltransferase-like domain-containing protein K02318 COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
D CELE_W07A8.2 ipla-3; Phospholipase A(2) K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
D CELE_F47A4.5 ipla-2; Intracellular phospholipase A2 K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 9, 2024