+E Replication protein KO
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DNA Replication Proteins - Orientia tsutsugamushi Boryong
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D OTBS_1582 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D OTBS_0440 hupA; histone-like DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D OTBS_0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D OTBS_0911 dnaB14; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D OTBS_0651 dnaB9; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D OTBS_1121 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D OTBS_1237 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E OTBS_0272 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E OTBS_0002 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E OTBS_0157 holC; DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E OTBS_0469 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E OTBS_2145 holB; DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E OTBS_1217 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E OTBS_1912 dnaX; DNA polymerase III gamma and tau chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E OTBS_1582 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E OTBS_0859 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E OTBS_1717 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E OTBS_1582 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E OTBS_0859 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
D OTBS_1318 dam17; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_1070 dam11; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_2013 dam31; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_0245 dam3; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_0126 dam2; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_1978 dam30; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_0616 dam5; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_0817 dam8; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_1432 dam21; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_1602 dam23; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D OTBS_1656 dam25; site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C Prevention of re-replication factors
B DNA Topoisomerases
C OTBS_0252 gyrA; DNA gyrase subunit A protein K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C OTBS_1419 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C OTBS_1844 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022