+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Shigella flexneri 8401 (serotype 5b)</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
D      Cap binding complex
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
D      Pre-mRNA cleavage factor IIm (CFIIm)
D      Cleavage and polyadenylation specificity factor (CPSF) complex
D      Cleavage stimulation factor (CSTF) complex
D      U7-dependent histone pre-mRNA processing factors
D      DRB sensitivity inducing factor (DSIF) complex
D      N6-methyltransferase complex
D      Poly(A) addition factors
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
D      TREX complex
D      TREX-2 complex
D      Nuclear pore complex
D      Ran-mediated transport factors
D      eIF4F and regulatory proteins
D      APOBEC1-ACF complex
D      Other transport factors
C    Surveillance factors
D      Surveillance complex
D      Protein phosphatase 2A
D      Other surveillance factors
C    Factors involved in mRNA localization
D      Cargo complex
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
D      Other mRNA localization factors
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
D      P-body specific factors
D      Stress granule specific factors
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
D      Lsm complex
D      5' exonucleases
D      Other 5'-3' decay factors
C    3'-5' decay
D      Core exosome factors
D      Exosome cofactors
D      TRAMP complex
D      Ski complex
D      Ccr4-NOT complex
D      Pan complex
D      Other 3'-5' decay factors
C    Other degradation factors
D      RNases
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A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        SFV_1106 rne; RNase E	K08300 rne; ribonuclease E [EC:3.1.26.12] 
E        SFV_3273 cafA; bundles of cytoplasmic filaments	K08301 rng; ribonuclease G [EC:3.1.26.-] 
E        SFV_2630 rnc; RNase III, ds RNA	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        SFV_4337 vacB; putative enzyme	K12573 rnr; ribonuclease R [EC:3.1.13.1] 
E        SFV_4319 yjeR; conserved hypothetical protein	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
E        SFV_3724 rhlB; putative ATP-dependent RNA helicase	K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7] 
E        SFV_0780 rhlE; putative ATP-dependent RNA helicase	K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] 
E        SFV_3192 deaD; inducible ATP-independent RNA helicase	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        SFV_3676 recQ; ATP-dependent DNA helicase	K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] 
D      Other RNA degradosome components
E        SFV_2676 eno; enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        SFV_3194 pnp; Polyribonucleotide nucleotidyltransferase	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        SFV_3722 rho; transcription termination factor Rho	K03628 rho; transcription termination factor Rho 
E        SFV_3578 pfkA; 6-phosphofructokinase I	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        SFV_0012 dnaK; chaperone Hsp70	K04043 dnaK; molecular chaperone DnaK 
E        SFV_4299 mopA; GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        SFV_4330 hfq; RNA-binding protein Hfq	K03666 hfq; host factor-I protein 
D      Others
E        SFV_2546 ppk; polyphosphate kinase	K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] 
E        SFV_0128 pcnB; poly(A) polymerase I	K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] 
E        SFV_2908 ygdP; putative invasion protein	K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] 
E        SFV_2809 csrA; carbon storage regulator	K03563 csrA; carbon storage regulator 
E        SFV_3278 yhdA; conserved hypothetical protein	K18765 csrD; RNase E specificity factor CsrD 
E        SFV_4000 menG; menaquinone biosynthesis, unknown	K02553 rraA; regulator of ribonuclease activity A 
E        SFV_4238 yjgD; conserved hypothetical protein	K09893 rraB; regulator of ribonuclease activity B 
E        SFV_3235 yhbJ; conserved hypothetical protein	K06958 rapZ; RNase adapter protein RapZ 
E        SFV_1794 hrpA; helicase, ATP-dependent	K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6] 
E        SFV_0132 hrpB; helicase, ATP-dependent	K03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6] 
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
D      Cofactors
D      Others
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#Last updated: April 25, 2024