+E Transcription factors KO
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Transcription Factors - Tribolium castaneum (red flour beetle)
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
D 662495 uncharacterized LOC662495 K09027 XBP1; X box-binding protein 1
D 663937 Jra; Jun-related antigen K04448 JUN; transcription factor AP-1
C AP-1(-like) components, Fos
D 655024 kay; kayak K09031 FOSLN; fos-like antigen, invertebrate
D 664528 proto-oncogene c-Fos K21406 ATF3; activating transcription factor 3
C AP-1(-like) components, Maf
D 658429 transcription factor MafA K07595 MAFA; transcription factor MAFA
D 656054 transcription factor MafK K09037 MAFF_G_K; transcription factor MAFF/G/K
C AP-1(-like) components, NF-E2
D 657062 cnc; cap-n-collar K09041 NFE2N; nuclear factor erythroid 2, invertebrate
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
D 663103 cyclic AMP-dependent transcription factor ATF-7 K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
D 658480 ATF4; activating transcription factor of chaperone K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
D 103315046 uncharacterized LOC103315046 K21548 CREBZF; ATF/CREB family transcription factor
C CREB
D 656052 cyclic AMP-responsive element-binding protein 1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 655333 cyclic AMP response element-binding protein A K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 661864 uncharacterized LOC661864 K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 663194 cyclic AMP-dependent transcription factor ATF-6 beta K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
C C/EBP-like factors
D 656953 CCAAT/enhancer-binding protein gamma K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
D 655869 CCAAT/enhancer-binding protein K10052 CEBPN; CCAAT/enhancer binding protein (C/EBP), invertebrate
C bZIP/PAR
D 103315025 uncharacterized LOC103315025 K09056 DBP; albumin D box-binding protein
D 655431 PDF1; hepatic leukemia factor K09057 HLF; hepatic leukemia factor
C Plant bZIP factors
C ZIP only
D 660017 argo; uncharacterized LOC660017 K12114 VRI; vrille
D 641612 Gt; giant K09062 GT; protein giant
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
D 662057 transcription factor 12 K15603 TCF4_12; transcription factor 4/12
C Myogenic transcription factors
D 660723 transcription factor SUM-1 K18484 MYF5; myogenic factor 5
C Achaete-Scute
D 103312560 protein atonal homolog 7 K09067 ASCL; achaete-scute complex protein
D 652936 Ase; asense K09067 ASCL; achaete-scute complex protein
D 652954 Ash; achaete-scute homolog K09067 ASCL; achaete-scute complex protein
C Tal/Twist/Atonal/Hen, Lymphoid factors
D 103313607 protein lyl-1 K09068 TAL; T-cell acute lymphocytic leukemia protein
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
D 641534 Twi; twist bHLH transcription factor K09069 TWIST; twist
D 100142400 transcription factor 15 K09070 TCF15; transcription factor 15
D 661028 heart- and neural crest derivatives-expressed protein 2 K18486 HAND2; heart-and neural crest derivatives-expressed protein 2
D 658355 Fer1; 48 related 1 K09073 PTF1A; pancreas-specific transcription factor 1a
D 657693 protein Fer3 K22400 FERD3L; Fer3-like protein
C Tal/Twist/Atonal/Hen, HEN
D 103312525 helix-loop-helix protein 1 K09075 NHLH; nescient helix-loop-helix protein
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
D 103314832 neurogenic differentiation factor 1 K08033 NEUROD1; neurogenic differentiation factor 1
D 659297 ato; atonal K09083 ATOH1_7; atonal protein 1/7
D 663089 Cato; cousin of atonal K09083 ATOH1_7; atonal protein 1/7
D 663144 Amos; absent MD neurons and olfactory sensilla K09083 ATOH1_7; atonal protein 1/7
D 656286 protein atonal homolog 8 K09084 ATOH8; atonal protein 8
D 659869 class A basic helix-loop-helix protein 15 K08040 BHLHB8; class B basic helix-loop-helix protein 8
C Tal/Twist/Atonal/Hen, Pancreatic factors
D 663664 class E basic helix-loop-helix protein 22 K09086 BHLHB4_5; class B basic helix-loop-helix protein 4/5
C Hairy, Hairy/E(SPL)
D 664077 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
D 656046 protein deadpan K09090 HESN; hairy and enhancer of split, invertebrate
D 660626 H; hairy K09090 HESN; hairy and enhancer of split, invertebrate
D 661225 enhancer of split mgamma protein K09090 HESN; hairy and enhancer of split, invertebrate
D 661436 enhancer of split mgamma protein K09090 HESN; hairy and enhancer of split, invertebrate
D 656543 hairy/enhancer-of-split related with YRPW motif protein K09091 HEY; hairy and enhancer of split related with YRPW motif
D 100141592 hairy/enhancer-of-split related with YRPW motif-like protein K27237 CWO; transcription factor CWO
C Hairy, Fungal regulators
C Factors with PAS domain
D 656242 Ss; spineless K09093 AHR; aryl hydrocarbon receptor
D 655772 hif1a; hypoxia-inducible factor 1-alpha K08268 HIF1A; hypoxia-inducible factor 1 alpha
D 658988 aryl hydrocarbon receptor nuclear translocator homolog K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
D 655476 Trh; protein trachealess K09098 NPAS1_3; neuronal PAS domain-containing protein 1/3
D 662372 neuronal PAS domain-containing protein 4 K26457 NPAS4; neuronal PAS domain-containing protein 4
D 655469 Clk; clock K02223 CLOCK; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
D 655516 CYCLE K02296 ARNTL; aryl hydrocarbon receptor nuclear translocator-like protein 1
D 656297 sim; single-minded homolog 1 K09100 SIM; single-minded
C Yabby
C INO
C HLH domain only
D 658540 protein extra-macrochaetae K17696 EMC; DNA-binding protein inhibitor ID, other
D 662502 COE; transcription factor collier K09103 EBF; early B-cell factor
D 103312596 neurogenin-3 K09104 TX; delilah
D 661965 helix-loop-helix protein delilah K09104 TX; delilah
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
D 659688 transcription factor EC K09455 MITF; microphthalmia-associated transcription factor
D 663308 upstream stimulatory factor 2 K09106 USF; upstream stimulatory factor
D 663039 sterol regulatory element-binding protein 1 K07197 SREBP1; sterol regulatory element-binding transcription factor 1
D 656093 transcription factor AP-4 K09108 TFAP4; transcription factor AP-4
C Cell cycle controlling factors, Myc
D 103314693 N-myc protein K09109 NMYC; N-myc proto-oncogene protein
C Cell cycle controlling factors, Mad/Max
D 664267 protein max K04453 MAX; Max protein
D 100142502 max-interacting protein 1 K09114 MXD; MAX dimerization protein
D 655367 max-binding protein MNT K09115 MNT; MAX-binding protein
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
D 660261 nuclear factor 1 C-type K09172 NFIN; nuclear factor I, invertebrate
C RF-X
D 664071 DNA-binding protein RFX2 K09173 RFX1_2_3; regulatory factor X 1/2/3
D 100141810 hypothetical protein K09175 RFX7; DNA-binding protein RFX7
C AP-2 (bHSH)
D 663046 AP-2; transcription factor AP-2 K09180 TFAP2N; transcription factor AP-2, invertebrate
B Zinc finger
C Cys4 thyroid hormone receptor-like
D 655046 E78; ecdysone-induced protein 78C K08701 NR1D3; nuclear receptor subfamily 1 group D member 3
D 660005 E75; ecdysone-inducible protein E75 K08701 NR1D3; nuclear receptor subfamily 1 group D member 3
D 663422 HR3; probable nuclear hormone receptor HR3 K14033 NR1F4; nuclear receptor subfamily 1 group F member 4
D 657515 Ecr; ecdysone receptor K14034 NR1H1; ecdysone receptor
D 656894 Hr96; hormone receptor in 96-like protein K14035 NR1IN; nuclear receptor subfamily 1 group I
C Cys4 hepatocyte nuclear factor 4-like
D 657032 Hnf4; hepatocyte nuclear factor 4-gamma K08704 NR2A4; hepatocyte nuclear factor 4
D 664148 NR2E4; dissatisfaction K07295 NR2AN; nuclear receptor subfamily 2 group A
D 661207 Usp; ultraspiracle nuclear receptor K14030 NR2B4; nuclear receptor subfamily 2 group B member 4
D 660024 Hr78; hormone receptor in 78-like protein K14031 NR2CN; nuclear receptor subfamily 2 group C
D 641541 Tll; tailless K08545 NR2E1; nuclear receptor subfamily 2 group E member 1
D 658951 Hr51; photoreceptor-specific nuclear receptor K08546 NR2E3; nuclear receptor subfamily 2 group E member 3
D 661886 nuclear receptor subfamily 2 group E member 1 K08546 NR2E3; nuclear receptor subfamily 2 group E member 3
D 655884 Svp; seven up K14032 NR2F3; nuclear receptor subfamily 2 group F member 3
C Cys4 estrogen receptor-like
D 654940 Err; estrogen-related receptor K08703 NR3BN; estrogen-related receptor ERR
C Cys4 nerve growth factor IB-like
D 100142491 Hr38; probable nuclear hormone receptor HR38 K08558 NR4A2; nuclear receptor subfamily 4 group A member 2
C Cys4 Fushi tarazu-F1-like
D 658929 NR5A3; nuclear hormone receptor FTZ-F1 K08705 NR5A3; nuclear receptor subfamily 5 group A member 3
D 658947 Hr39; nuclear hormone receptor FTZ-F1 beta K08705 NR5A3; nuclear receptor subfamily 5 group A member 3
C Cys4 germ cell nuclear factor
D 663168 HR4; hormone receptor 4 K09185 NR6AN; nuclear receptor subfamily 6 group A
C Cys4 Knirps/DAX1-like
D 652949 Eg; eagle K08706 NR0AN; nuclear receptor subfamily 0 group A
D 656920 Kni; knirps K08706 NR0AN; nuclear receptor subfamily 0 group A
C Cys4 GATA-factors
D 660745 Grn; grain K17894 GATA2; GATA-binding protein 2
D 661820 GATAa; pannier K09183 GATA4; GATA-binding protein 4
D 661909 serpent; transcription factor GATA-4 K09183 GATA4; GATA-binding protein 4
D 655534 GATA zinc finger domain-containing protein 1 K23407 GATAD1; GATA zinc finger domain-containing protein 1
D 656529 transcriptional repressor p66-alpha K23194 GATAD2; transcriptional repressor p66
D 656772 arginine-glutamic acid dipeptide repeats protein K05628 RERE; arginine-glutamic acid dipeptide repeats protein
D 664398 metastasis-associated protein MTA3 K11660 MTA; metastasis-associated protein MTA
D 657738 transcriptional regulator ATRX homolog K10779 ATRX; transcriptional regulator ATRX
D 659723 transcriptional regulator ATRX homolog K10779 ATRX; transcriptional regulator ATRX
C Cys2His2 SP/KLF family and related proteins
D 658531 Btd; buttonhead K09195 SP5; transcription factor Sp5
D 660965 transcription factor Sp4 K09200 SP-N; transcription factor Sp, invertebrate
D 103313193 Krueppel-like factor 6 K09206 KLF5; krueppel-like factor 5
D 100142007 Krueppel-like factor 6 K09207 KLF6_7; krueppel-like factor 6/7
D 660309 Krueppel-like factor 8 K09205 KLF8_12; krueppel-like factor 8/12
D 656654 transcription factor Sp3 K09210 KLF15; krueppel-like factor 15
D 659436 early growth response protein 1-B K09203 EGR1; early growth response protein 1
D 100141671 hkb; zinc finger protein 678 K12379 HKB; huckebein
C Cys2His2 GLI-like
D 103313418 zinc finger protein GLIS1 K09232 GLIS1_3; zinc finger protein GLIS1/3
D 658487 zinc finger protein GLIS2 homolog K09233 GLIS2; zinc finger protein GLIS2
D 656812 pair-rule protein odd-paired K09227 ZICN; zinc finger protein ZIC, invertebrate
D 658653 Ci; cubitus interruptus K16799 CI; transcriptional activator cubitus interruptus
C Cys2His2 Snail
D 654928 Esg; escargot K05706 SNAI2; snail 2
D 659972 protein snail K09219 SCRT; scratch
D 659794 insulinoma-associated protein 1a K25795 INSM; insulinoma-associated protein
C Cys2His2 BTB-ZF factors
D 659978 Ttk; tramtrack K09237 TTK; tramtrack
D 659193 Br-c; broad-complex K02174 BR-C; broad-complex core protein
D 100141866 protein tramtrack, alpha isoform K27896 K27896; TTK-type BTB protein
D 103312699 protein bric-a-brac 1-like K27896 K27896; TTK-type BTB protein
D 656792 protein bric-a-brac 1 K27896 K27896; TTK-type BTB protein
D 658867 chinmo; broad-complex core protein isoforms 1/2/3/4/5 K27896 K27896; TTK-type BTB protein
D 659105 longitudinals lacking protein-like K27896 K27896; TTK-type BTB protein
D 659496 Lola; longitudinals lacking K27896 K27896; TTK-type BTB protein
D 660340 Fru; fruitless K27896 K27896; TTK-type BTB protein
D 660343 protein tramtrack, beta isoform K27896 K27896; TTK-type BTB protein
D 660399 zinc finger and BTB domain-containing protein 49 K27896 K27896; TTK-type BTB protein
D 660434 broad-complex core protein isoform 6-like K27896 K27896; TTK-type BTB protein
D 661019 longitudinals lacking protein, isoforms H/M/V K27896 K27896; TTK-type BTB protein
D 661906 protein bric-a-brac 1 K27896 K27896; TTK-type BTB protein
D 663068 uncharacterized LOC663068 K27896 K27896; TTK-type BTB protein
D 663820 protein abrupt K27896 K27896; TTK-type BTB protein
D 664575 zinc finger protein 3 homolog K27896 K27896; TTK-type BTB protein
C Cys2His2 BED
D 107398328 zinc finger BED domain-containing protein 4 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C Cys2His2 PRDM
D 100142159 Blimp-1; PR domain zinc finger protein 1 K24501 PRDM1; PR domain zinc finger protein 1 [EC:2.1.1.-]
D 664087 transcription factor hamlet K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
D 100141754 oocyte zinc finger protein XlCOF6 K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-]
D 103312589 zinc finger protein ZFP69B K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-]
D 663212 zinc finger protein 595 K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-]
D 664165 uncharacterized LOC664165 K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
D 663462 PR domain zinc finger protein 10 K24643 PRDM10; PR domain zinc finger protein 10 [EC:2.1.1.-]
D 659388 zinc finger protein 560 K24645 PRDM13; PR domain zinc finger protein 13 [EC:2.1.1.-]
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
D 660734 sob; protein sister of odd and bowel K09215 OSR; odd-skipped
D 660789 Odd; protein odd-skipped K09215 OSR; odd-skipped
D 660842 bowel; protein bowel K09215 OSR; odd-skipped
D 663753 protein ovo K09216 OVOL; ovo
D 664110 ikaros family zinc finger protein K09220 IKZF; IKAROS family zinc finger protein
D 659757 GFI1; zinc finger protein Gfi-1 K09223 GFI1; growth factor independent 1
D 663289 sens; senseless K09223 GFI1; growth factor independent 1
D 660305 schnurri; uncharacterized LOC660305 K09239 HIVEP; human immunodeficiency virus type I enhancer-binding protein
D 658276 zinc finger protein jing homolog K17452 AEBP2; zinc finger protein AEBP2
D 664166 zinc finger protein PLAG1 K19484 PLAG1; zinc finger protein PLAG1
D 662162 Peb; pebbled K20210 RREB1; ras-responsive element-binding protein 1
D 664174 B-cell lymphoma/leukemia 11B K22045 BCL11A; B-cell lymphoma/leukemia 11A
D 103313401 zinc finger X-chromosomal protein K23195 CTCF; transcriptional repressor CTCF
D 659562 protein suppressor of hairy wing K23195 CTCF; transcriptional repressor CTCF
D 662791 transcriptional repressor CTCF K23195 CTCF; transcriptional repressor CTCF
D 103313055 regulatory protein ADR1 K23317 MTF1; metal regulatory transcription factor 1
D 660322 disco-r; zinc finger protein basonuclin-2 K24146 BNC; zinc finger protein basonuclin
D 103312607 transcription factor IIIA K09191 GTF3A; general transcription factor IIIA
D 103313160 gastrula zinc finger protein XlCGF8.2DB K09191 GTF3A; general transcription factor IIIA
D 103313973 oocyte zinc finger protein XlCOF15 K09191 GTF3A; general transcription factor IIIA
D 661508 Pho; pleiohomeotic K09201 YY; transcription factor YY
D 658625 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
D 659822 zinc finger protein rotund K23480 ZNF362_384; zinc finger protein 362/384
D 103314902 hypothetical protein K22870 ZNF423; zinc finger protein 423
D 655026 zinc finger protein 423 homolog K22870 ZNF423; zinc finger protein 423
D 100141547 zinc finger protein 570 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100141551 zinc finger protein 2 homolog K09228 KRAB; KRAB domain-containing zinc finger protein
D 100141745 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 100141811 zinc finger protein 2 homolog K09228 KRAB; KRAB domain-containing zinc finger protein
D 100141859 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 100141931 zinc finger protein 271-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 100142025 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 100142302 zinc finger protein 260 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100142339 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 100142467 gastrula zinc finger protein XlCGF28.1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 100142561 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 103312505 zinc finger protein 320 K09228 KRAB; KRAB domain-containing zinc finger protein
D 103312659 zinc finger protein 112 K09228 KRAB; KRAB domain-containing zinc finger protein
D 103313120 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 103313190 zinc finger protein 2-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 103314128 zinc finger protein 43 K09228 KRAB; KRAB domain-containing zinc finger protein
D 103314200 zinc finger protein 91 K09228 KRAB; KRAB domain-containing zinc finger protein
D 103315039 zinc finger protein 708 K09228 KRAB; KRAB domain-containing zinc finger protein
D 107397979 gastrula zinc finger protein XlCGF26.1-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 655555 zinc finger protein 37 K09228 KRAB; KRAB domain-containing zinc finger protein
D 655937 zinc finger protein 2-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 656007 grau; zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 658436 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 661121 gastrula zinc finger protein XlCGF26.1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 661879 gastrula zinc finger protein XlCGF57.1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 662621 zinc finger protein 271 K09228 KRAB; KRAB domain-containing zinc finger protein
D 662742 zinc finger protein 260 K09228 KRAB; KRAB domain-containing zinc finger protein
D 663633 zinc finger protein OZF K09228 KRAB; KRAB domain-containing zinc finger protein
D 100142245 fez; fez family zinc finger K24502 FEZF; Fez family zinc finger protein
D 661767 zinc finger protein castor homolog 1-like K25209 CASZ1; zinc finger protein castor
D 659857 histone H4 transcription factor K25794 HINFP; histone H4 transcription factor
D 103313104 sal; homeotic protein spalt-major K19871 SALL; sal-like protein
D 658622 ATM interactor K27895 ATMIN; ATM interactor
D 641605 Kr; Kruppel K09231 KR; krueppel
D 660041 Krueppel-like factor 11 K13943 CBT; cabut
D 656763 Hb; hunchback K09213 HB; hunchback
D 641548 Gl; glass K09214 GL; glass
D 660674 drm; protein drumstick K22535 DRM; drumstick
D 663679 zinc finger protein 2 homolog K28002 su(Hw); protein suppressor of hairy wing
C Cys2HisCys zinc factors
D 659918 Ush; zinc finger protein u-shaped K17441 ZFPM1; zinc finger protein ZFPM1
D 656837 histone acetyltransferase KAT8 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D 658964 histone acetyltransferase KAT7 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
D 659405 histone acetyltransferase KAT6A K11306 MYST4; histone acetyltransferase MYST4 [EC:2.3.1.48]
D 664310 histone acetyltransferase Tip60 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D 656299 lethal(3)malignant brain tumor-like protein 4 K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
D 662145 uncharacterized protein C16C10.8 K15263 LYER; cell growth-regulating nucleolar protein
C Cys3His zinc factors
D 656960 roquin-1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 661055 uncharacterized LOC661055 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D 658843 trithorax; histone-lysine N-methyltransferase trithorax K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
D 658793 CXXC-type zinc finger protein 1 K14960 CXXC1; COMPASS component SPP1
D 103312925 DNA N6-methyl adenine demethylase K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
D 100141742 DNA (cytosine-5)-methyltransferase PliMCI-like K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 659466 jmjC domain-containing histone demethylation protein 1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
D 660910 PHD finger protein 19 K11485 MTF2; metal regulatory transcription factor 2
D 659177 protein shuttle craft K12236 NFX1; transcriptional repressor NF-X1
D 661164 CCHC-type zinc finger protein CG3800 K09250 CNBP; cellular nucleic acid-binding protein
D 661245 zinc finger C4H2 domain-containing protein K24369 ZC4H2; zinc finger C4H2 domain-contaning protein
D 664517 interferon regulatory factor 2-binding protein 2 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B Helix-turn-helix
C Homeo domain ANTP: HOXL
D 652930 Lab; labial K09301 HOX_1; homeobox protein HoxA/B/D1
D 641554 Mxp; maxillopedia K09302 HOX_2; homeobox protein HoxA/B2
D 641533 Zen; zerknullt K09303 HOX_3; homeobox protein HoxA/B/D3
D 652932 Zen2; zerknullt-related K09303 HOX_3; homeobox protein HoxA/B/D3
D 641550 Dfd; transcription factor deformed K09304 HOX_4; homeobox protein HoxA/B/C/D4
D 641600 Cx; cephalothorax K09305 HOX_5; homeobox protein HoxA/B/C5
D 654512 Ftz; fushi tarazu K09305 HOX_5; homeobox protein HoxA/B/C5
D 641535 Ubx; ultrabithorax K09307 HOX_7; homeobox protein HoxA/B7
D 641545 Ptl; prothoraxless K09307 HOX_7; homeobox protein HoxA/B7
D 641595 Abd-A; abdominal-A K09307 HOX_7; homeobox protein HoxA/B7
D 641530 Ind; intermediate neuroblasts defective K09310 GSH; homeobox protein GSH
D 641536 Cad; caudal K09312 CDX1_4; homeobox protein CDX1/4
D 654511 Eve; even-skipped K09320 EVX; homeobox even-skipped homolog protein
D 663801 Gbx2; homeobox protein unplugged K09321 GBX; homeobox protein GBX
D 103313502 homeobox protein Hox-D4a K08025 HLXB9; homeobox protein HB9
D 103315016 homeobox protein MOX-2 K09322 MEOX; homeobox protein MOX
D 641596 Abd-B; abdominal-B K09300 ABDB; homeobox protein abdominal-B and related proteins
C Homeo domain ANTP: NKL
D 655878 homeobox protein slou K09309 NKX1; homeobox protein Nkx-1
D 662616 nkx2.1; homeobox protein Nkx-2.1 K09342 NKX2-1; homeobox protein Nkx-2.1
D 656094 Tc-vnd; ventral nervous system defective K08029 NKX2-2; homeobox protein Nkx-2.2
D 663892 homeobox protein HMX3 K09995 NKX3-2; homeobox protein Nkx-3.2
D 655792 homeobox protein Hmx K09349 NKX5; homeobox protein Nkx-5
D 658426 homeobox protein Nkx-6.2 K08030 NKX6-1; homeobox protein Nkx-6.1
D 641606 Dll; distal-less K18488 DLX2; homeobox protein DLX2
D 663858 c15; T-cell leukemia homeobox protein 2 K15607 TLX3; T-cell leukemia homeobox protein 3
D 103312830 H2.0-like homeobox protein K09339 HLX1; homeobox protein HLX1
D 663591 Ems; empty spiracles K09317 EMX; homeobox protein EMX
D 641551 En; engrailed K09319 EN; homeobox protein engrailed
D 661645 En; engrailed K09319 EN; homeobox protein engrailed
D 100141842 homeobox protein ceh-5 K09341 MSX; homeobox protein MSX
D 641531 Msh; muscle segment homeodomain protein K09341 MSX; homeobox protein MSX
D 663938 muscle segmentation homeobox K09341 MSX; homeobox protein MSX
D 103315017 Hex; hematopoietically-expressed homeobox protein hhex K08024 HHEX; homeobox protein HEX
D 662953 homeobox protein ceh-30 K09360 BARHL; BarH-like
D 103313323 Bsh; brain-specific homeobox protein homolog K24874 BSX; brain-specific homeobox protein
D 103312269 dbx; homeobox protein DBX1 K24875 DBX; homeobox protein DBX
C Homeo domain Paired-related
D 656101 Al; aristaless K09452 ARX; homeobox protein aristaless-related
D 658445 Mu; munster K09452 ARX; homeobox protein aristaless-related
D 661394 gsc; goosecoid K09324 GSC; homeobox protein goosecoid
D 641553 Otd1; orthodenticle-1 K09326 OTX1; homeobox protein OTX1
D 641604 Otd-2; orthodenticle-2 K18490 OTX2; homeobox protein OTX2
D 657741 homeobox protein unc-4 K09328 UNC4; homeobox protein Unc-4
D 103315103 Prx; paired mesoderm homeobox protein 2 K09329 PRRX; paired mesoderm homeobox protein
D 100141864 paired mesoderm homeobox protein 2A K09330 PHOX2; paired mesoderm homeobox protein 2
D 655465 Shox; short stature homeobox protein 2 K09331 SHOX; short stature homeobox protein
D 662264 Rx; retinal homeobox K09332 RAX; retina and anterior neural fold homeobox protein
D 655933 Vsx; visual system homeobox protein K09336 VSX2; visual system homeobox protein 2
D 662159 otp; orthopedia K24901 OTP; homeobox protein orthopedia
D 664378 Poxm; paired box pox-meso protein K09382 PAX1_9; paired box protein 1/9
D 656415 shaven; paired box protein Pax-5 K15608 PAX2; paired box protein 2
D 655066 Prd; paired K09381 PAX3_7; paired box protein 3/7
D 663027 gsb-n; gooseberry-neuro K09381 PAX3_7; paired box protein 3/7
D 663057 gooseberry; protein gooseberry K09381 PAX3_7; paired box protein 3/7
D 661804 Poxn; pox neuro K09383 PAX5; paired box protein 5
D 663509 toy; paired box protein Pax-6 K08031 PAX6; paired box protein 6
D 664444 Ey; eyeless K08031 PAX6; paired box protein 6
C Homeo domain LIM
D 662583 Tup; tailup K09370 ISL1; insulin gene enhancer protein ISL-1
D 655506 LMX-HD; LIM homeobox transcription factor 1-alpha K09371 LMX1; LIM homeobox transcription factor 1
D 655586 LMX-HD; LIM homeobox transcription factor 1-beta.1 K09371 LMX1; LIM homeobox transcription factor 1
D 657972 lim1; LIM/homeobox protein Lhx5 K09372 LHX1; LIM homeobox protein 1
D 658656 ap; apterous a K09373 LHX2_9; LIM homeobox protein 2/9
D 658719 Ap; apterous K09373 LHX2_9; LIM homeobox protein 2/9
D 662120 lim3; lim homeobox 3 K09374 LHX3_4; LIM homeobox protein 3/4
D 663031 muscle LIM protein 1 K09377 CSRP; cysteine and glycine-rich protein
C Homeo domain POU
D 656845 Nub; nubbin K09364 POU2F; POU domain transcription factor, class 2
D 656764 Vvl; ventral vein lacking K09365 POU3F; POU domain transcription factor, class 3
D 661038 acj6; inhibitory POU protein K09366 POU4F; POU domain transcription factor, class 4
C Homeo domain SINE
D 660875 So; sine oculis K15614 SIX1; homeobox protein SIX1
D 664012 Six3; optix K19473 SIX3_6; homeobox protein SIX3/6
D 657176 six4; homeobox protein SIX4 K15615 SIX4; homeobox protein SIX4
C Homeo domain ZF
D 657717 zfh2; zinc finger homeobox protein 4 K09378 ZFHX3; zinc finger homeobox protein 3
D 100141776 zinc finger protein 1 K23560 ZEB2; zinc finger homeobox protein 2
C Homeo domain CUT
D 659250 homeobox protein cut K09313 CUTL; homeobox protein cut-like
D 103314820 homeobox protein onecut K08026 ONECUT1; one cut domain, family member 1 (hepatocyte nuclear factor 6)
C Homeo domain PROS
D 660328 pros; homeobox protein prospero K20211 PROX1; prospero homeobox 1
C Homeo domain TALE
D 641540 Exd; extradenticle K09355 PBX1; pre-B-cell leukemia transcription factor 1
D 103312892 homeobox protein TGIF2LX K19383 TGIF1; homeobox protein TGIF1
D 661221 Vis; vismay K19383 TGIF1; homeobox protein TGIF1
D 652944 Iro; homeobox protein araucan K24889 IRX; iroquois-class homeodomain protein IRX
D 660345 mirr; homeobox protein caupolican K24889 IRX; iroquois-class homeodomain protein IRX
D 100142330 homeobox protein Mohawk K24890 MKX; homeobox protein Mohawk
D 658681 homeobox protein PKNOX2 K24891 PKNOX; homeobox protein PKNOX
D 641464 Hth; homothorax K16672 HTH; homeobox protein homothorax
C Homeo domain other
D 103314807 dan; protein distal antenna K22536 DAN; distal antenna
D 103315010 homeobox protein rough K09362 K09362; homeo domain only family, other
C Fork head/winged helix developmental regulators
D 641542 Fkh; fork head K08035 FOXA2; forkhead box protein A2, hepatocyte nuclear factor 3-beta
D 100142409 fork head domain-containing protein crocodile K09396 FOXC; forkhead box protein C
D 662438 Slp; sloppy-paired K09385 FOXG; forkhead box protein G
D 662507 FD6; fork head domain transcription factor slp2 K09385 FOXG; forkhead box protein G
D 100141565 forkhead box protein N3 K09407 FOXN; forkhead box protein N
D 657747 forkhead box protein P4 K09407 FOXN; forkhead box protein N
C Fork head/winged helix tissue-specific regulators
D 103314004 forkhead box protein N2 K09402 FOXJ1; forkhead box protein J1
C Fork head/winged helix cell cycle-controlling factors, E2F
D 656396 transcription factor E2F2 K09389 E2F2; transcription factor E2F2
D 660070 transcription factor E2F5 K04682 E2F4_5; transcription factor E2F4/5
C Fork head/winged helix cell cycle-controlling factors, DP
D 662175 transcription factor Dp-1 K04683 TFDP1; transcription factor Dp-1
C Fork head/winged helix other regulators
D 659891 forkhead box protein D3 K09397 FOXD; forkhead box protein D
D 100142613 forkhead box protein F1 K09399 FOXF; forkhead box protein F
D 658300 forkhead box protein K1 K09404 FOXK; forkhead box protein K
D 663700 forkhead box protein L2 K09405 FOXL; forkhead box protein L
D 664090 forkhead box protein O K09408 FOXO3; forkhead box protein O3
D 657917 forkhead box protein P1 K09409 FOXP2_4; forkhead box protein P2/4
D 654864 fork head domain-containing protein FD2 K09411 FOXX; forkhead box protein, other
D 656430 fork head domain-containing protein FD4 K09411 FOXX; forkhead box protein, other
D 656599 protein lin-31 K09411 FOXX; forkhead box protein, other
C Heat shock factors
D 103314511 heat shock factor protein K09414 HSF1; heat shock transcription factor 1
C Tryptophan clusters Myb, Myb-factors
D 664494 myb-related protein B K09420 MYB; transcriptional activator Myb
C Tryptophan clusters Myb, Myb-like factors
D 100142168 uncharacterized LOC100142168 K09427 ADF1; Adh transcription factor 1
D 103313281 transcription factor Adf-1 K09427 ADF1; Adh transcription factor 1
D 103314284 transcription factor Adf-1 K09427 ADF1; Adh transcription factor 1
D 103315182 hypothetical protein K09427 ADF1; Adh transcription factor 1
C Tryptophan clusters Ets-type
D 655028 ecdysone-induced protein 74EF K09428 ELF1_2_4; E74-like factor 1/2/4
D 103312853 ETS homologous factor K17102 EHF; ETS homologous factor
D 663895 ets DNA-binding protein pokkuri K03211 ETV6_7; ETS translocation variant 6/7
D 659984 ETS-like protein pointed, isoform P2/D K02678 ETS1; C-ets-1
D 661753 DNA-binding protein D-ETS-3 K09436 FLI1; friend leukemia integration 1 transcription factor
D 658879 Ets97D; GA binding protein transcription factor, alpha subunit 60kDa K09441 GABPA; GA-binding protein transcription factor, alpha
D 656847 DNA-binding protein D-ETS-4 K09442 SPDEF; SAM pointed domain-containing ETS transcription factor
D 663364 DNA-binding protein D-ETS-6 K09443 K09443; ETS-type family, other
C Tryptophan clusters interferon-regulating factors
C TEA domain
D 658922 Sd; scalloped K09448 TEAD; transcriptional enhancer factor
C ARID
D 100141527 trithorax group protein osa K11653 ARID1; AT-rich interactive domain-containing protein 1
D 664298 AT-rich interactive domain-containing protein 2 K11765 ARID2; AT-rich interactive domain-containing protein 2
D 657345 retained; protein dead ringer K25856 ARID3; AT-rich interactive domain-containing protein 3
D 660367 AT-rich interactive domain-containing protein 4B K19195 ARID4B; AT-rich interactive domain-containing protein 4B
D 656495 H6; serine protease H6 K25857 ARID5; AT-rich interactive domain-containing protein 5
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
D 659499 ird; relish K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
D 641547 Dl; dorsal K09254 REL; c-Rel proto-oncogene protein
C RHR (Rel homology region) Ankyrin only
D 657221 Cact; cactus K04734 NFKBIA; NF-kappa-B inhibitor alpha
D 658004 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
D 659698 spz5; spatzle 5 K09454 GABPB; GA-binding protein transcription factor, beta
C RHR (Rel homology region) NF-AT
D 663601 rel; uncharacterized LOC663601 K17335 NFAT5; nuclear factor of activated T-cells 5
C STAT
D 657965 Stat; signal-transducer and activator of transcription protein K11224 STAT5B; signal transducer and activator of transcription 5B
C p53
D 655327 cellular tumor antigen p53 K10148 TP73; tumor protein p73
D 657307 cellular tumor antigen p53 K10148 TP73; tumor protein p73
C MADS-box regulators of differentiation, MEF-2
D 660448 myocyte-specific enhancer factor 2 K09260 MEF2A; MADS-box transcription enhancer factor 2A
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
D 661307 Srf; serum response factor K04378 SRF; serum response factor
C SAND domain-containing proteins
D 655086 deformed epidermal autoregulatory factor 1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
C TATA-binding proteins
D 107397998 TATA box-binding protein-like protein 1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 657721 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 657798 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
C HMG SOX
D 660601 Sox21a; Sox21a K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 660661 Sox21b; transcription factor Sox-2 K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 660717 dichaete K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 660774 SOX domain-containing protein dichaete K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 663351 SoxN; transcription factor Sox-3 K16796 SOX2; transcription factor SOX2 (SOX group B)
D 661892 protein SOX-15 K23581 SOX4; transcription factor SOX4 (SOX group C)
D 656907 Cic; capicua K20225 CIC; capicua transcriptional repressor
D 656425 uncharacterized LOC656425 K21643 BBX; HMG box transcription factor BBX
C HMG TCF-1
D 641465 Pan; pangolin K04491 TCF7L2; transcription factor 7-like 2
C HMG2-related
D 661780 FACT complex subunit Ssrp1 K09272 SSRP1; FACT complex subunit SSRP1/POB3
C UBF
D 100141998 nucleolar transcription factor 1-like K09273 UBTF; upstream-binding transcription factor
D 658441 nucleolar transcription factor 1 K09273 UBTF; upstream-binding transcription factor
C Other HMG box factors
C Heteromeric CCAAT factors
D 661458 nuclear transcription factor Y subunit alpha K08064 NFYA; nuclear transcription factor Y, alpha
D 658226 nuclear transcription factor Y subunit B-4 K08065 NFYB; nuclear transcription Y subunit beta
D 655290 nuclear transcription factor Y subunit gamma K08066 NFYC; nuclear transcription factor Y, gamma
C Grainyhead
D 660755 protein grainyhead K09275 TFCP2; transcription factor CP2 and related proteins
D 663386 transcription factor CP2-like protein 1 K09275 TFCP2; transcription factor CP2 and related proteins
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
D 656063 Y-box factor homolog K09276 YBX1; Y-box-binding protein 1
C Cold-shock domain factors, FRG Y2-like
C Runt
D 657742 run; runt K20213 RUN; RUNX transcription factor Runt
D 660060 lz; lozenge K20214 LZ; RUNX transcription factor Lozenge
D 657356 runt-like protein K09280 RUNXA_B; runt-related transcription factor
D 657431 runt-related transcription factor 2 K09280 RUNXA_B; runt-related transcription factor
C MYRF
D 656437 myelin regulatory factor K24768 MYRF; myelin regulatory factor [EC:3.4.-.-]
B Other transcription factors
C HMGI(Y)
D 658140 uncharacterized LOC658140 K09282 HMGA1; high mobility group AT-hook protein 1
C NUPR
D 661355 nuclear protein 1 K15626 NUPR1; nuclear protein 1
E Line #4
C Pocket domain Rb
D 660494 retinoblastoma-like protein 1 K04681 RBL1; retinoblastoma-like protein 1
C Pocket domain CBP
D 664565 CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C T-box
D 652935 Byn; brachyury K10172 BRA; brachyury protein
D 660602 Org-1; optomotor blind related gene 1 protein K10175 TBX1; T-box protein 1
D 661159 Omb; optomotor-blind-like K10176 TBX2; T-box protein 2
D 654492 Doc; dorsocross K10180 TBX6; T-box protein 6
D 661373 H15; T-box transcription factor TBX20 K10185 TBX20; T-box protein 20
D 661420 H15; H15 protein K10185 TBX20; T-box protein 20
C DMRT
D 103314548 doublesex- and mab-3-related transcription factor A2 K19491 DMRT4_5; doublesex- and mab-3-related transcription factor 4/5
D 664586 doublesex- and mab-3-related transcription factor A2 K19491 DMRT4_5; doublesex- and mab-3-related transcription factor 4/5
C LRRFIP
D 659671 leucine-rich repeat flightless-interacting protein 2 K26434 LRRFIP; leucine-rich repeat flightless-interacting protein
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
D 656966 calmodulin-binding transcription activator 2 K21596 CAMTA; calmodulin-binding transcription activator
D 663985 transcription factor glial cells missing K21598 GCM; chorion-specific transcription factor GCM
D 103313113 transmembrane protein 18 K22145 TMEM18; transmembrane protein 18
D 662096 coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2
D 663984 Su(H); suppressor of hairless K06053 RBPSUH; recombining binding protein suppressor of hairless
D 103313681 uncharacterized LOC103313681 K23804 GON4L; GON-4-like protein
D 662482 transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
D 663167 myelin expression factor 2 K24992 MYEF2; myelin expression factor 2
D 103314350 NF-kappa-B-repressing factor K26458 NKRF; NF-kappa-B-repressing factor
D 655998 protein ecdysoneless K28083 ECD; protein ecdysoneless
D 652934 Dac; dachshund homolog 1 K28157 DACH; dachshund
#
AProkaryotic type
B Helix-turn-helix
C AraC family
C LysR family
C DeoR family
C LacI family
C GntR family
C TetR/AcrR family
C Lrp/AsnC family
C LuxR family
C MarR family
C MerR family
C Fur family
C IclR family
C CRP/FNR family
C Rrf2 family
C ArsR family
C XRE family
C PadR family
C Other families
B Ribbon-helix-helix
C CopG family
C Other families
B Other transcription factors
C BglG family
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 17, 2025
#
Classification taken and modified from TRANSFAC 7.0