Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
   ABC transporters
   Solute carrier family
     SLC5
     SLC6
       SLC6A1 (GAT1) [HSA:6529] [KO:K05034]
       SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
         D05458  Phentermine (USAN/INN) <US>
         D05459  Phentermine hydrochloride (USP) <US>
         D07444  Amfepramone (INN)
         D03801  Diethylpropion hydrochloride (USP) <US>
         D00367  Mazindol (JAN/USP/INN) <JP>
         D08513  Sibutramine (INN)
         D02571  Sibutramine hydrochloride (USAN)
         D01304  Amezinium metilsulfate (JAN) <JP>
         D08030  Guanethidine (INN)
         D02237  Guanethidine sulfate (USAN)
         D04382  Guanethidine sulfate (JP17)
         D07875  Doxepin (INN)
         D00814  Doxepin hydrochloride (USP) <US>
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D06007  Tapentadol (USAN/INN)
         D10199  Tapentadol hydrochloride (JAN) <JP/US>
         D07791  Desipramine (INN)
         D00812  Desipramine hydrochloride (JAN/USP) <US>
         D08070  Imipramine (INN)
         D00815  Imipramine hydrochloride (JP17/USP) <JP/US>
         D08071  Imipramine pamoate (USP) <US>
         D07727  Clomipramine (INN)
         D00811  Clomipramine hydrochloride (JP17/USP) <JP/US>
         D00394  Trimipramine (USAN/INN)
         D02408  Trimipramine maleate (JAN/USAN) <JP/US>
         D08140  Lofepramine (INN)
         D01285  Lofepramine hydrochloride (JAN/USAN) <JP>
         D07448  Amitriptyline (INN)
         D00809  Amitriptyline hydrochloride (JP17/USP) <JP/US>
         D08288  Nortriptyline (INN)
         D00816  Nortriptyline hydrochloride (JP17/USP/INN) <JP/US>
         D08447  Protriptyline (INN)
         D00484  Protriptyline hydrochloride (USP) <US>
         D07872  Dosulepin (INN)
         D01546  Dothiepin hydrochloride (USAN) <JP>
         D00228  Amoxapine (JP17/USP/INN) <JP/US>
         D02566  Maprotiline (USAN)
         D00818  Maprotiline hydrochloride (JP17/USP) <JP/US>
         D05200  Nomifensine maleate (USAN)
         D08673  Viloxazine (INN)
         D02572  Viloxazine hydrochloride (USAN)
         D07591  Bupropion (INN)
         D00817  Bupropion hydrochloride (JAN/USP) <US>
         D07938  Bupropion hydrobromide (USAN) <US>
         D08670  Venlafaxine (INN)
         D00821  Venlafaxine hydrochloride (JAN/USAN) <JP/US>
         D08222  Milnacipran (INN)
         D01107  Milnacipran hydrochloride (JAN/USAN) <JP/US>
         D08472  Reboxetine (INN)
         D02573  Reboxetine mesylate (USAN)
         D07880  Duloxetine (INN)
         D01179  Duloxetine hydrochloride (JAN/USP) <JP/US>
         D07793  Desvenlafaxine (INN) <US>
         D02570  Desvenlafaxine succinate (USAN) <US>
         D07445  Amfetamine (INN) <US>
         D02074  Amphetamine sulfate (USP) <US>
         D03740  Dextroamphetamine (USAN)
         D02078  Dextroamphetamine sulfate (USP) <US>
         D08187  Metamfetamine (INN)
         D02242  Methamphetamine hydrochloride (JP17/USP) <JP/US>
         D04999  Methylphenidate (USAN/INN) <US>
         D01296  Methylphenidate hydrochloride (JAN/USP) <JP/US>
         D07473  Atomoxetine (USP/INN)
         D02574  Atomoxetine hydrochloride (JAN/USP) <JP/US>
         D07806  Dexmethylphenidate (INN)
         D03721  Dexmethylphenidate hydrochloride (USAN) <US>
         D08130  Lisdexamfetamine (INN)
         D04747  Lisdexamfetamine dimesylate (USAN) <JP/US>
         D02080  Phendimetrazine tartrate (USP) <US>
         D02170  Indeloxazine hydrochloride (JAN/USAN)
         D02704  Tampramine fumarate (USAN)
         D03491  Cidoxepin hydrochloride (USAN)
         D04473  Hydroxyamphetamine hydrobromide (USP)
         D04781  Lortalamine (USAN/INN)
         D05119  Napamezole hydrochloride (USAN)
         D05120  Napitane mesylate (USAN)
         D05173  Nisoxetine (USAN/INN)
         D05284  Oxaprotiline hydrochloride (USAN)
         D05454  Phenmetrazine hydrochloride (USP)
         D05663  Pyrovalerone hydrochloride (USAN)
         D05692  Radafaxine hydrochloride (USAN)
         D05997  Talopram hydrochloride (USAN)
         D06004  Tandamine hydrochloride (USAN)
         D07334  Imipraminoxide (INN)
         D07449  Amitriptylinoxide (INN)
         D07514  Benzfetamine (INN)
         D07515  Benzfetamine hydrochloride <US>
         D08072  Imipraminoxide hydrochloride
         D08077  Indeloxazine (INN)
         D08347  Phendimetrazine (INN)
         D08348  Phendimetrazine hydrochloride
         D09340  Esreboxetine (USAN/INN)
         D09341  Esreboxetine succinate (USAN)
         D09890  Edivoxetine (USAN/INN)
         D09891  Edivoxetine hydrochloride (USAN)
         D10072  Levomilnacipran (USAN/INN)
         D10088  Amitifadine (USAN)
         D10089  Amitifadine hydrochloride (USAN)
         D10133  Levomilnacipran hydrochloride (USAN) <US>
         D10443  Liafensine (USAN)
         D10697  Centanafadine (USAN)
         D10698  Centanafadine hydrochloride (USAN)
         D10700  Dasotraline (USAN/INN)
         D10870  Dasotraline hydrochloride (USAN)
         D11172  Midomafetamine (USAN/INN)
         D11315  Solriamfetol (USAN)
         D11328  Solriamfetol hydrochloride (USAN) <US>
         D11619  Desvenlafaxine succinate anhydrous <US>
         D11622  Amphetamine aspartate monohydrate
         D11623  Dextroamphetamine saccharate
         D11688  Ampreloxetin (USAN/INN)
         D11689  Ampreloxetin hydrochloride (USAN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
       SLC6A4 (HTT) [HSA:6532] [KO:K05037]
         D05458  Phentermine (USAN/INN) <US>
         D05459  Phentermine hydrochloride (USP) <US>
         D07945  Fenfluramine (INN)
         D04148  Fenfluramine hydrochloride (USAN)
         D07805  Dexfenfluramine (INN)
         D03713  Dexfenfluramine hydrochloride (USAN)
         D00367  Mazindol (JAN/USP/INN) <JP>
         D08513  Sibutramine (INN)
         D02571  Sibutramine hydrochloride (USAN)
         D07875  Doxepin (INN)
         D00814  Doxepin hydrochloride (USP) <US>
         D03649  Dapoxetine hydrochloride (USAN)
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D07791  Desipramine (INN)
         D00812  Desipramine hydrochloride (JAN/USP) <US>
         D08070  Imipramine (INN)
         D00815  Imipramine hydrochloride (JP17/USP) <JP/US>
         D08071  Imipramine pamoate (USP) <US>
         D07727  Clomipramine (INN)
         D00811  Clomipramine hydrochloride (JP17/USP) <JP/US>
         D00394  Trimipramine (USAN/INN)
         D02408  Trimipramine maleate (JAN/USAN) <JP/US>
         D08140  Lofepramine (INN)
         D01285  Lofepramine hydrochloride (JAN/USAN) <JP>
         D07448  Amitriptyline (INN)
         D00809  Amitriptyline hydrochloride (JP17/USP) <JP/US>
         D08288  Nortriptyline (INN)
         D00816  Nortriptyline hydrochloride (JP17/USP/INN) <JP/US>
         D08447  Protriptyline (INN)
         D00484  Protriptyline hydrochloride (USP) <US>
         D07872  Dosulepin (INN)
         D01546  Dothiepin hydrochloride (USAN) <JP>
         D00228  Amoxapine (JP17/USP/INN) <JP/US>
         D00326  Fluoxetine (USAN/INN)
         D00823  Fluoxetine hydrochloride (JAN/USP) <US>
         D07704  Citalopram (USP/INN)
         D00822  Citalopram hydrobromide (USAN) <US>
         D07705  Citalopram hydrochloride
         D02362  Paroxetine (USP/INN)
         D02260  Paroxetine hydrochloride hydrate (JP17) <JP/US>
         D05374  Paroxetine hydrochloride (USP) <US>
         D05375  Paroxetine mesylate (USAN) <US>
         D02360  Sertraline (INN)
         D00825  Sertraline hydrochloride (JAN/USAN) <JP/US>
         D02787  Alaproclate (USAN/INN)
         D07984  Fluvoxamine (INN)
         D00824  Fluvoxamine maleate (JP17/USAN) <JP/US>
         D07913  Escitalopram (INN)
         D02567  Escitalopram oxalate (JAN/USAN) <JP/US>
         D08626  Trazodone (INN)
         D00820  Trazodone hydrochloride (JAN/USP) <JP/US>
         D08670  Venlafaxine (INN)
         D00821  Venlafaxine hydrochloride (JAN/USAN) <JP/US>
         D08222  Milnacipran (INN)
         D01107  Milnacipran hydrochloride (JAN/USAN) <JP/US>
         D07880  Duloxetine (INN)
         D01179  Duloxetine hydrochloride (JAN/USP) <JP/US>
         D07793  Desvenlafaxine (INN) <US>
         D02570  Desvenlafaxine succinate (USAN) <US>
         D09698  Vilazodone (USAN/INN)
         D09699  Vilazodone hydrochloride (USAN) <US>
         D10184  Vortioxetine (USAN)
         D10185  Vortioxetine hydrobromide (JAN/USAN) <JP/US>
         D08187  Metamfetamine (INN)
         D02242  Methamphetamine hydrochloride (JP17/USP) <JP/US>
         D07806  Dexmethylphenidate (INN)
         D03721  Dexmethylphenidate hydrochloride (USAN) <US>
         D02170  Indeloxazine hydrochloride (JAN/USAN)
         D03491  Cidoxepin hydrochloride (USAN)
         D04788  Lubazodone hydrochloride (USAN)
         D05491  Pirandamine hydrochloride (USAN)
         D07334  Imipraminoxide (INN)
         D07449  Amitriptylinoxide (INN)
         D08072  Imipraminoxide hydrochloride
         D08077  Indeloxazine (INN)
         D10072  Levomilnacipran (USAN/INN)
         D10088  Amitifadine (USAN)
         D10089  Amitifadine hydrochloride (USAN)
         D10133  Levomilnacipran hydrochloride (USAN) <US>
         D10443  Liafensine (USAN)
         D10697  Centanafadine (USAN)
         D10698  Centanafadine hydrochloride (USAN)
         D11169  Lumateperone (USAN/INN)
         D11170  Lumateperone tosylate (USAN)
         D11172  Midomafetamine (USAN/INN)
         D11619  Desvenlafaxine succinate anhydrous <US>
         D11688  Ampreloxetin (USAN/INN)
         D11689  Ampreloxetin hydrochloride (USAN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       SLC6A9 (GLYT1) [HSA:6536] [KO:K05038]
     SLC9
     SLC10
     SLC12
     SLC18
     SLC22
     SLC29
     SLC34
   Major facilitator superfamily
   Other transporters
 
 Enzymes
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: November 20, 2019

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