Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
 
 Ion channels
   Ligand-gated ion channels
   Voltage-gated ion channels
     Sodium channels
     Calcium channels
       CACNA1-T [HSA:8911 8912 8913] [KO:K04856 K04855 K04854]
         D08217  Mibefradil (INN)
         D05024  Mibefradil dihydrochloride (USAN)
         D07520  Bepridil (INN)
         D00631  Bepridil hydrochloride (USAN) <JP>
         D00539  Ethosuximide (JP17/USP/INN) <JP/US>
         D00404  Methsuximide (USP) <US>
         D00399  Valproic acid (USP) <US>
         D00304  Divalproex sodium (USP) <US>
         D00710  Valproate sodium (USAN) <JP/US>
         D08667  Calcium valproate
         D00538  Zonisamide (JP17/USP/INN) <JP/US>
         D02630  Penfluridol (USAN/INN)
         D07971  Flunarizine (INN)
         D01303  Flunarizine hydrochloride (JAN/USAN)
         D02633  Lomerizine hydrochloride (JAN) <JP>
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       CACNA1B [HSA:774] [KO:K04849]
       CACNA1-L [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
       CACNA1S [HSA:779] [KO:K04857]
       CACNA2D [HSA:781 9254 55799 93589] [KO:K04858 K04859 K04860 K04861]
       CACNA2D1 [HSA:781] [KO:K04858]
       CACNA2D2 [HSA:9254] [KO:K04859]
     Potassium channels
     Inward rectifier channels (Kir)
     Ryanodine receptors (RYR)
     Transient receptor potential channels
   Other ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
   Oxidoreductases (EC1)
     Dehydrogenases [EC:1.1.1.-]
     Dehydrogenases [EC:1.2.1.-]
       ALDH [HSA:217 219 224] [KO:K00128]
       SSADH [HSA:7915] [KO:K00139]
         D00399  Valproic acid (USP) <US>
         D00304  Divalproex sodium (USP) <US>
         D00710  Valproate sodium (USAN) <JP/US>
         D08667  Calcium valproate
 
 
 
 
     Dehydrogenases [EC:1.3.-.-]
     Amine oxidases [EC:1.4.3.-]
     Dihydrofolate reductase [EC:1.5.1.3]
     NAD(P)H dehydrogenase [EC:1.6.5.2]
     Peroxidase [EC:1.11.1.-]
     Peroxygenase [EC:1.11.2.-]
     Dioxygenases [EC:1.13.11.-]
     Prolyl 4-hydroxylase [EC:1.14.11.2]
     HIF hydroxylase [EC:1.14.11.29]
     Nitic oxide synthase [EC:1.14.13.39]
     Cytochrome P450 [EC:1.14.14.-]
     Other monooxygenases [EC:1.14.16.- 1.14.17.- 1.14.18.-]
     Prostaglandin synthase [EC:1.14.99.1]
     Xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
     Ribonucleoside-diphosphate reductase [EC:1.17.4.1]
     Vitamin-K-epoxide reductase [EC:1.17.4.4]
     Thyroxine 5'-deiodinase [EC:1.21.99.4]
   Transferases (EC2)
     Methyltransferases [EC:2.1.1.-]
     Acyltransferases [EC:2.3.1.-]
     gamma-Glutamyltransferase [EC:2.3.2.2]
     E3 ubiquitin-protein ligase [EC:2.3.2.27]
     ATP citrate synthase [EC:2.3.3.8]
     Hexosyltransferases [EC:2.4.1.-]
     Pentosyltransferases [EC:2.4.2.-]
     Alkyl/Aryl transferases [EC:2.5.1.-]
     Aminotransferase [EC:2.6.1.-]
       ABAT [HSA:18] [KO:K13524]
         D00399  Valproic acid (USP) <US>
         D00304  Divalproex sodium (USP) <US>
         D00710  Valproate sodium (USAN) <JP/US>
         D08667  Calcium valproate
         D00535  Vigabatrin (JAN/USP/INN) <JP/US>
 
 
 
 
 
     Phosphotransferase [EC:2.7.1.-]
     DNA polymerase [EC:2.7.7.7]
     Reverse transcriptase [EC:2.7.7.49]
   Hydrolases (EC3)
   Lyases (EC4)
     Carboxy-lyases [EC:4.1.1.-]
       GAD [HSA:2571 2572] [KO:K01580]
         D00399  Valproic acid (USP) <US>
         D00304  Divalproex sodium (USP) <US>
         D00710  Valproate sodium (USAN) <JP/US>
         D08667  Calcium valproate
 
 
 
 
       ODC1 [HSA:4953] [KO:K01581]
       HDC [HSA:3067] [KO:K01590]
       DDC [HSA:1644] [KO:K01593]
       AMD1 [HSA:262] [KO:K01611]
       GGCX [HSA:2677] [KO:K10106]
     Aldehyde-lyases [EC:4.1.2.-]
     Phosphorus-oxygen lyases [EC:4.6.1.-]
   Isomerases (EC5)
   Ligases (EC6)
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: February 27, 2020

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