Target-based Classification of Drugs

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 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
   ABC transporters
   Solute carrier family
     SLC5
     SLC6
       SLC6A1 (GAT1) [HSA:6529] [KO:K05034]
       SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
         D05458  Phentermine (USAN/INN) <US>
         D05459  Phentermine hydrochloride (USP) <US>
         D07444  Amfepramone (INN)
         D03801  Diethylpropion hydrochloride (USP) <US>
         D00367  Mazindol (JAN/USP/INN) <JP>
         D08513  Sibutramine (INN)
         D02571  Sibutramine hydrochloride (USAN)
         D01304  Amezinium metilsulfate (JAN) <JP>
         D08030  Guanethidine (INN)
         D02237  Guanethidine sulfate (USAN)
         D04382  Guanethidine sulfate (JP17)
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D06007  Tapentadol (USAN/INN)
         D10199  Tapentadol hydrochloride (JAN) <JP/US>
         D07791  Desipramine (INN)
         D00812  Desipramine hydrochloride (JAN/USP) <US>
         D08070  Imipramine (INN)
         D00815  Imipramine hydrochloride (JP17/USP) <JP/US>
         D08071  Imipramine pamoate (USP)
         D07727  Clomipramine (INN)
         D00811  Clomipramine hydrochloride (JP17/USP) <JP/US>
         D00394  Trimipramine (USAN/INN)
         D02408  Trimipramine maleate (JAN/USAN) <JP/US>
         D08140  Lofepramine (INN)
         D01285  Lofepramine hydrochloride (JAN/USAN) <JP>
         D07448  Amitriptyline (INN)
         D00809  Amitriptyline hydrochloride (JP17/USP) <JP/US>
         D08288  Nortriptyline (INN)
         D00816  Nortriptyline hydrochloride (JP17/USP/INN) <JP/US>
         D08447  Protriptyline (INN)
         D00484  Protriptyline hydrochloride (USP) <US>
         D07875  Doxepin (INN)
         D00814  Doxepin hydrochloride (USP) <US>
         D07872  Dosulepin (INN)
         D01546  Dothiepin hydrochloride (USAN) <JP>
         D00228  Amoxapine (JP17/USP/INN) <JP/US>
         D02566  Maprotiline (USAN)
         D00818  Maprotiline hydrochloride (JP17/USP) <JP/US>
         D05200  Nomifensine maleate (USAN)
         D08673  Viloxazine (INN)
         D02572  Viloxazine hydrochloride (USAN)
         D07591  Bupropion (INN)
         D00817  Bupropion hydrochloride (JAN/USP) <US>
         D07938  Bupropion hydrobromide (USAN) <US>
         D08670  Venlafaxine (INN)
         D00821  Venlafaxine hydrochloride (JAN/USAN) <JP/US>
         D08222  Milnacipran (INN)
         D01107  Milnacipran hydrochloride (JAN/USAN) <JP/US>
         D08472  Reboxetine (INN)
         D02573  Reboxetine mesylate (USAN)
         D07880  Duloxetine (INN)
         D01179  Duloxetine hydrochloride (JAN/USAN) <JP/US>
         D07793  Desvenlafaxine (INN) <US>
         D02570  Desvenlafaxine succinate (USAN) <US>
         D07445  Amfetamine (INN) <US>
         D02074  Amphetamine sulfate (USP) <US>
         D03740  Dextroamphetamine (USAN)
         D02078  Dextroamphetamine sulfate (USP) <US>
         D08187  Metamfetamine (INN)
         D02242  Methamphetamine hydrochloride (JP17/USP) <JP/US>
         D04999  Methylphenidate (USAN/INN) <US>
         D01296  Methylphenidate hydrochloride (JAN/USP) <JP/US>
         D07473  Atomoxetine (USP/INN)
         D02574  Atomoxetine hydrochloride (JAN/USP) <JP/US>
         D07806  Dexmethylphenidate (INN)
         D03721  Dexmethylphenidate hydrochloride (USAN) <US>
         D03491  Cidoxepin hydrochloride (USAN)
         D05173  Nisoxetine (USAN/INN)
         D05663  Pyrovalerone hydrochloride (USAN)
         D05997  Talopram hydrochloride (USAN)
         D07334  Imipraminoxide (INN)
         D07449  Amitriptylinoxide (INN)
         D08072  Imipraminoxide hydrochloride
         D09340  Esreboxetine (USAN/INN)
         D09341  Esreboxetine succinate (USAN)
         D09890  Edivoxetine (USAN/INN)
         D09891  Edivoxetine hydrochloride (USAN)
         D10072  Levomilnacipran (USAN/INN)
         D10088  Amitifadine (USAN)
         D10089  Amitifadine hydrochloride (USAN)
         D10133  Levomilnacipran hydrochloride (USAN) <US>
         D10443  Liafensine (USAN)
         D10697  Centanafadine (USAN)
         D10698  Centanafadine hydrochloride (USAN)
         D10700  Dasotraline (USAN/INN)
         D10870  Dasotraline hydrochloride (USAN)
       SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
       SLC6A4 (HTT) [HSA:6532] [KO:K05037]
         D05458  Phentermine (USAN/INN) <US>
         D05459  Phentermine hydrochloride (USP) <US>
         D07945  Fenfluramine (INN)
         D04148  Fenfluramine hydrochloride (USAN)
         D07805  Dexfenfluramine (INN)
         D03713  Dexfenfluramine hydrochloride (USAN)
         D00367  Mazindol (JAN/USP/INN) <JP>
         D08513  Sibutramine (INN)
         D02571  Sibutramine hydrochloride (USAN)
         D03649  Dapoxetine hydrochloride (USAN)
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D07791  Desipramine (INN)
         D00812  Desipramine hydrochloride (JAN/USP) <US>
         D08070  Imipramine (INN)
         D00815  Imipramine hydrochloride (JP17/USP) <JP/US>
         D08071  Imipramine pamoate (USP)
         D07727  Clomipramine (INN)
         D00811  Clomipramine hydrochloride (JP17/USP) <JP/US>
         D00394  Trimipramine (USAN/INN)
         D02408  Trimipramine maleate (JAN/USAN) <JP/US>
         D08140  Lofepramine (INN)
         D01285  Lofepramine hydrochloride (JAN/USAN) <JP>
         D07448  Amitriptyline (INN)
         D00809  Amitriptyline hydrochloride (JP17/USP) <JP/US>
         D08288  Nortriptyline (INN)
         D00816  Nortriptyline hydrochloride (JP17/USP/INN) <JP/US>
         D08447  Protriptyline (INN)
         D00484  Protriptyline hydrochloride (USP) <US>
         D07875  Doxepin (INN)
         D00814  Doxepin hydrochloride (USP) <US>
         D07872  Dosulepin (INN)
         D01546  Dothiepin hydrochloride (USAN) <JP>
         D00228  Amoxapine (JP17/USP/INN) <JP/US>
         D00326  Fluoxetine (USAN/INN)
         D00823  Fluoxetine hydrochloride (JAN/USP) <US>
         D07704  Citalopram (USP/INN)
         D00822  Citalopram hydrobromide (USAN) <US>
         D07705  Citalopram hydrochloride
         D02362  Paroxetine (USP/INN)
         D02260  Paroxetine hydrochloride hydrate (JP17) <JP/US>
         D05374  Paroxetine hydrochloride (USP) <US>
         D05375  Paroxetine mesylate (USAN) <US>
         D02360  Sertraline (INN)
         D00825  Sertraline hydrochloride (JAN/USAN) <JP/US>
         D02787  Alaproclate (USAN/INN)
         D07984  Fluvoxamine (INN)
         D00824  Fluvoxamine maleate (JP17/USAN) <JP/US>
         D07913  Escitalopram (INN)
         D02567  Escitalopram oxalate (JAN/USAN) <JP/US>
         D08626  Trazodone (INN)
         D00820  Trazodone hydrochloride (JAN/USP) <JP/US>
         D08670  Venlafaxine (INN)
         D00821  Venlafaxine hydrochloride (JAN/USAN) <JP/US>
         D08222  Milnacipran (INN)
         D01107  Milnacipran hydrochloride (JAN/USAN) <JP/US>
         D07880  Duloxetine (INN)
         D01179  Duloxetine hydrochloride (JAN/USAN) <JP/US>
         D07793  Desvenlafaxine (INN) <US>
         D02570  Desvenlafaxine succinate (USAN) <US>
         D09698  Vilazodone (USAN/INN)
         D09699  Vilazodone hydrochloride (USAN) <US>
         D10184  Vortioxetine (USAN)
         D10185  Vortioxetine hydrobromide (JAN/USAN) <US>
         D08187  Metamfetamine (INN)
         D02242  Methamphetamine hydrochloride (JP17/USP) <JP/US>
         D07806  Dexmethylphenidate (INN)
         D03721  Dexmethylphenidate hydrochloride (USAN) <US>
         D03491  Cidoxepin hydrochloride (USAN)
         D05491  Pirandamine hydrochloride (USAN)
         D07334  Imipraminoxide (INN)
         D07449  Amitriptylinoxide (INN)
         D08072  Imipraminoxide hydrochloride
         D10072  Levomilnacipran (USAN/INN)
         D10088  Amitifadine (USAN)
         D10089  Amitifadine hydrochloride (USAN)
         D10133  Levomilnacipran hydrochloride (USAN) <US>
         D10443  Liafensine (USAN)
         D10697  Centanafadine (USAN)
         D10698  Centanafadine hydrochloride (USAN)
       SLC6A9 (GLYT1) [HSA:6536] [KO:K05038]
     SLC9
     SLC10
     SLC12
     SLC18
     SLC22
     SLC29
   Major facilitator superfamily
   Other transporters
 
 Enzymes
 
 Not elsewhere classified

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Last updated: June 19, 2018

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