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1. Oxidoreductases
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2. Transferases
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2.1 Transferring one-carbon groups
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2.2 Transferring aldehyde or ketonic groups
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2.3 Acyltransferases
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2.4 Glycosyltransferases
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2.5 Transferring alkyl or aryl groups, other than methyl groups
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2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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2.5.1.1 dimethylallyltranstransferase
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2.5.1.2 thiamine pyridinylase
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2.5.1.3 thiamine phosphate synthase
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2.5.1.5 galactose-6-sulfurylase
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2.5.1.6 methionine adenosyltransferase
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2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase
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2.5.1.9 riboflavin synthase
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2.5.1.10 (2E,6E)-farnesyl diphosphate synthase
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2.5.1.15 dihydropteroate synthase
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CC1G_15556 folic acid synthesis protein
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K13939 FOL1; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15]
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2.5.1.16 spermidine synthase
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2.5.1.17 corrinoid adenosyltransferase
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2.5.1.18 glutathione transferase
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2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase
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2.5.1.20 rubber cis-polyprenylcistransferase
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2.5.1.21 squalene synthase
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2.5.1.22 spermine synthase
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2.5.1.23 sym-norspermidine synthase
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2.5.1.24 discadenine synthase
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2.5.1.25 tRNA-uridine aminocarboxypropyltransferase
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2.5.1.26 alkylglycerone-phosphate synthase
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2.5.1.27 adenylate dimethylallyltransferase (AMP-dependent)
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2.5.1.28 dimethylallylcistransferase
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2.5.1.29 geranylgeranyl diphosphate synthase
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2.5.1.30 heptaprenyl diphosphate synthase
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2.5.1.31 ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
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2.5.1.32 15-cis-phytoene synthase
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2.5.1.34 4-dimethylallyltryptophan synthase
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2.5.1.35 aspulvinone dimethylallyltransferase
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2.5.1.36 trihydroxypterocarpan dimethylallyltransferase
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2.5.1.38 isonocardicin synthase
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2.5.1.39 4-hydroxybenzoate polyprenyltransferase
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2.5.1.41 phosphoglycerol geranylgeranyltransferase
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2.5.1.42 geranylgeranylglycerol-phosphate geranylgeranyltransferase
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2.5.1.43 nicotianamine synthase
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2.5.1.44 homospermidine synthase
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2.5.1.45 homospermidine synthase (spermidine-specific)
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2.5.1.46 deoxyhypusine synthase
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2.5.1.47 cysteine synthase
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2.5.1.48 cystathionine gamma-synthase
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2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase
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2.5.1.50 zeatin 9-aminocarboxyethyltransferase
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2.5.1.51 beta-pyrazolylalanine synthase
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2.5.1.52 L-mimosine synthase
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2.5.1.53 uracilylalanine synthase
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2.5.1.54 3-deoxy-7-phosphoheptulonate synthase
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2.5.1.55 3-deoxy-8-phosphooctulonate synthase
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2.5.1.56 N-acetylneuraminate synthase
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2.5.1.57 N-acylneuraminate-9-phosphate synthase
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2.5.1.58 protein farnesyltransferase
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2.5.1.59 protein geranylgeranyltransferase type I
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2.5.1.60 protein geranylgeranyltransferase type II
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2.5.1.61 hydroxymethylbilane synthase
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2.5.1.62 chlorophyll synthase
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2.5.1.63 adenosyl-fluoride synthase
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2.5.1.65 O-phosphoserine sulfhydrylase
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2.5.1.66 N2-(2-carboxyethyl)arginine synthase
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2.5.1.67 chrysanthemyl diphosphate synthase
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2.5.1.68 (2Z,6E)-farnesyl diphosphate synthase
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2.5.1.69 lavandulyl diphosphate synthase
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2.5.1.70 naringenin 8-dimethylallyltransferase
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2.5.1.71 leachianone-G 2''-dimethylallyltransferase
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2.5.1.72 quinolinate synthase
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2.5.1.73 O-phospho-L-seryl-tRNA:Cys-tRNA synthase
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2.5.1.74 1,4-dihydroxy-2-naphthoate polyprenyltransferase
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2.5.1.75 tRNA dimethylallyltransferase
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2.5.1.76 cysteate synthase
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2.5.1.78 6,7-dimethyl-8-ribityllumazine synthase
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2.5.1.79 thermospermine synthase
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2.5.1.80 7-dimethylallyltryptophan synthase
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2.5.1.81 geranylfarnesyl diphosphate synthase
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2.5.1.82 hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
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2.5.1.83 hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
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2.5.1.84 all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
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2.5.1.85 all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
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2.5.1.86 trans,polycis-decaprenyl diphosphate synthase
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2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
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2.5.1.88 trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific]
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2.5.1.89 tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
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2.5.1.90 all-trans-octaprenyl-diphosphate synthase
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2.5.1.91 all-trans-decaprenyl-diphosphate synthase
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2.5.1.92 (2Z,6Z)-farnesyl diphosphate synthase
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2.5.1.93 4-hydroxybenzoate geranyltransferase
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2.5.1.94 adenosyl-chloride synthase
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2.5.1.95 xanthan ketal pyruvate transferase
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2.5.1.96 4,4'-diapophytoene synthase
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2.5.1.97 pseudaminic acid synthase
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2.5.1.98 Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase
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2.5.1.100 fumigaclavine A dimethylallyltransferase
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2.5.1.101 N,N'-diacetyllegionaminate synthase
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2.5.1.102 geranyl-pyrophosphate---olivetolic acid geranyltransferase
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2.5.1.103 presqualene diphosphate synthase
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2.5.1.104 N1-aminopropylagmatine synthase
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2.5.1.105 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
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2.5.1.106 tryprostatin B synthase
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2.5.1.107 verruculogen prenyltransferase
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2.5.1.108 2-(3-amino-3-carboxypropyl)histidine synthase
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2.5.1.109 brevianamide F prenyltransferase (deoxybrevianamide E-forming)
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2.5.1.110 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase
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2.5.1.111 4-hydroxyphenylpyruvate 3-dimethylallyltransferase
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2.5.1.112 adenylate dimethylallyltransferase (ADP/ATP-dependent)
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2.5.1.113 [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
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2.5.1.114 tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase
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2.5.1.115 homogentisate phytyltransferase
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2.5.1.116 homogentisate geranylgeranyltransferase
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2.5.1.117 homogentisate solanesyltransferase
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2.5.1.118 beta-(isoxazolin-5-on-2-yl)-L-alanine synthase
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2.5.1.119 beta-(isoxazolin-5-on-4-yl)-L-alanine synthase
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2.5.1.120 aminodeoxyfutalosine synthase
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2.5.1.121 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
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2.5.1.122 4-O-dimethylallyl-L-tyrosine synthase
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2.5.1.123 flaviolin linalyltransferase
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2.5.1.124 6-linalyl-2-O,3-dimethylflaviolin synthase
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2.5.1.125 7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase
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2.5.1.126 norspermine synthase
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2.5.1.127 caldopentamine synthase
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2.5.1.128 N4-bis(aminopropyl)spermidine synthase
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2.5.1.129 flavin prenyltransferase
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2.5.1.130 2-carboxy-1,4-naphthoquinone phytyltransferase
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2.5.1.131 (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
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2.5.1.132 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase
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2.5.1.133 bacteriochlorophyll a synthase
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2.5.1.134 cystathionine beta-synthase (O-acetyl-L-serine)
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2.5.1.135 validamine 7-phosphate valienyltransferase
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2.5.1.136 2-acylphloroglucinol 4-prenyltransferase
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2.5.1.137 2-acyl-4-prenylphloroglucinol 6-prenyltransferase
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2.5.1.138 coumarin 8-geranyltransferase
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2.5.1.139 umbelliferone 6-dimethylallyltransferase
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2.5.1.140 N-(2-amino-2-carboxyethyl)-L-glutamate synthase
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2.5.1.141 heme o synthase
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2.5.1.142 nerylneryl diphosphate synthase
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2.5.1.143 pyridinium-3,5-biscarboxylic acid mononucleotide synthase
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2.5.1.144 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent)
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2.5.1.145 phosphatidylglycerol---prolipoprotein diacylglyceryl transferase
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2.5.1.146 3-geranyl-3-[(Z)-2-isocyanoethenyl]indole synthase
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2.5.1.147 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase
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2.5.1.148 lycopaoctaene synthase
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2.5.1.149 lycopene elongase/hydratase (flavuxanthin-forming)
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2.5.1.150 lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming)
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2.5.1.151 alkylcobalamin dealkylase
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2.5.1.152 D-histidine 2-aminobutanoyltransferase
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2.5.1.153 adenosine tuberculosinyltransferase
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2.5.1.154 corrinoid adenosyltransferase EutT
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2.5.1.155 phosphoglycerol geranylfarnesyltransferase
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2.5.1.156 geranylfarnesylglycerol-phosphate geranylfarnesyltransferase
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2.5.1.157 rRNA small subunit aminocarboxypropyltransferase
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2.5.1.158 hexaprenyl diphosphate synthase (prenyl-diphosphate specific)
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2.5.1.159 hapalindole G dimethylallyltransferase
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2.6 Transferring nitrogenous groups
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2.7 Transferring phosphorus-containing groups
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2.7.1 Phosphotransferases with an alcohol group as acceptor
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2.7.2 Phosphotransferases with a carboxy group as acceptor
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2.7.3 Phosphotransferases with a nitrogenous group as acceptor
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2.7.4 Phosphotransferases with a phosphate group as acceptor
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2.7.6 Diphosphotransferases
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2.7.6.1 ribose-phosphate diphosphokinase
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2.7.6.2 thiamine diphosphokinase
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2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
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CC1G_15556 folic acid synthesis protein
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K13939 FOL1; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15]
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2.7.6.4 nucleotide diphosphokinase
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2.7.6.5 GTP diphosphokinase
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2.7.7 Nucleotidyltransferases
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2.7.8 Transferases for other substituted phosphate groups
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2.7.9 Phosphotransferases with paired acceptors
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2.7.10 Protein-tyrosine kinases
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2.7.11 Protein-serine/threonine kinases
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2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
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2.7.13 Protein-histidine kinases
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2.7.14 Protein-arginine kinases
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2.7.99 Other protein kinases
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2.8 Transferring sulfur-containing groups
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2.9 Transferring selenium-containing groups
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2.10 Transferring molybdenum- or tungsten-containing groups
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3. Hydrolases
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4. Lyases
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4.1 Carbon-carbon lyases
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4.1.1 Carboxy-lyases
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4.1.2 Aldehyde-lyases
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4.1.2.2 ketotetrose-phosphate aldolase
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4.1.2.4 deoxyribose-phosphate aldolase
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4.1.2.5 L-threonine aldolase
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4.1.2.8 indole-3-glycerol-phosphate lyase
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4.1.2.9 phosphoketolase
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4.1.2.10 (R)-mandelonitrile lyase
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4.1.2.11 hydroxymandelonitrile lyase
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4.1.2.12 2-dehydropantoate aldolase
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4.1.2.13 fructose-bisphosphate aldolase
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4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase
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4.1.2.17 L-fuculose-phosphate aldolase
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4.1.2.18 2-dehydro-3-deoxy-L-pentonate aldolase
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4.1.2.19 rhamnulose-1-phosphate aldolase
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4.1.2.20 2-dehydro-3-deoxyglucarate aldolase
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4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
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4.1.2.22 fructose-6-phosphate phosphoketolase
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4.1.2.23 3-deoxy-D-manno-octulosonate aldolase
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4.1.2.24 dimethylaniline-N-oxide aldolase
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4.1.2.25 dihydroneopterin aldolase
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CC1G_15556 folic acid synthesis protein
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K13939 FOL1; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15]
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4.1.2.26 phenylserine aldolase
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4.1.2.27 sphinganine-1-phosphate aldolase
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4.1.2.28 2-dehydro-3-deoxy-D-pentonate aldolase
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4.1.2.29 5-dehydro-2-deoxyphosphogluconate aldolase
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4.1.2.32 trimethylamine-oxide aldolase
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4.1.2.33 fucosterol-epoxide lyase
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4.1.2.34 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase
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4.1.2.35 propioin synthase
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4.1.2.36 lactate aldolase
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4.1.2.38 benzoin aldolase
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4.1.2.40 tagatose-bisphosphate aldolase
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4.1.2.42 D-threonine aldolase
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4.1.2.43 3-hexulose-6-phosphate synthase
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4.1.2.44 2,3-epoxybenzoyl-CoA dihydrolase
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4.1.2.45 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
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4.1.2.46 aliphatic (R)-hydroxynitrile lyase
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4.1.2.47 (S)-hydroxynitrile lyase
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4.1.2.48 low-specificity L-threonine aldolase
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4.1.2.49 L-allo-threonine aldolase
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4.1.2.50 6-carboxytetrahydropterin synthase
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4.1.2.51 2-dehydro-3-deoxy-D-gluconate aldolase
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4.1.2.52 4-hydroxy-2-oxoheptanedioate aldolase
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4.1.2.53 2-keto-3-deoxy-L-rhamnonate aldolase
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4.1.2.54 L-threo-3-deoxy-hexylosonate aldolase
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4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
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4.1.2.56 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase
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4.1.2.57 sulfofructosephosphate aldolase
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4.1.2.58 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase
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4.1.2.59 dihydroneopterin phosphate aldolase
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4.1.2.60 dihydroneopterin triphosphate aldolase
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4.1.2.61 feruloyl-CoA hydratase/lyase
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4.1.2.62 5-deoxyribulose 1-phosphate aldolase
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4.1.2.63 2-hydroxyacyl-CoA lyase
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4.1.2.64 2-dehydro-3-deoxy-L-fuconate aldolase
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4.1.2.65 ferulate hydratase/lyase
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4.1.2.66 4-coumarate hydratase/lyase
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4.1.3 Oxo-acid-lyases
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4.1.99 Other carbon-carbon lyases
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4.2 Carbon-oxygen lyases
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4.3 Carbon-nitrogen lyases
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4.4 Carbon-sulfur lyases
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4.5 Carbon-halide lyases
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4.6 Phosphorus-oxygen lyases
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4.7 carbon-phosphorus lyases
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4.8 Nitrogen-oxygen lyases
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4.98 ATP-independent chelatases
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4.99 Other lyases
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5. Isomerases
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6. Ligases
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7. Translocases
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