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 1. Oxidoreductases
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2. Transferases
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3. Hydrolases
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 4. Lyases
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4.1 Carbon-carbon lyases
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4.2 Carbon-oxygen lyases
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4.3 Carbon-nitrogen lyases
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4.4 Carbon-sulfur lyases
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4.5 Carbon-halide lyases
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4.6 Phosphorus-oxygen lyases
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4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
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4.6.1.1 adenylate cyclase
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4.6.1.2 guanylate cyclase
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 103177390 soluble guanylate cyclase 88E-like
103173806 soluble guanylate cyclase 88E-like
103185780 gucy1a2; LOW QUALITY PROTEIN: guanylate cyclase soluble subunit alpha-2
103187183 gucy1a1; LOW QUALITY PROTEIN: guanylate cyclase soluble subunit alpha-1
103187184 gucy1b1; guanylate cyclase soluble subunit beta-1 isoform X2
103187614 guanylate cyclase soluble subunit beta-2-like
121849600 guanylate cyclase soluble subunit beta-1 isoform X1
121850339 guanylate cyclase soluble subunit beta-1 isoform X1
103172259 heat-stable enterotoxin receptor-like
103179559 LOW QUALITY PROTEIN: retinal guanylyl cyclase 2
103181010 atrial natriuretic peptide receptor 2
103174800 atrial natriuretic peptide receptor 2-like
103186579 gucy2g; guanylate cyclase 2G
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K01769 E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
K01769 E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K22600 GUCY2G; guanylate cyclase 2G [EC:4.6.1.2]
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4.6.1.6 cytidylate cyclase
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4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
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4.6.1.13 phosphatidylinositol diacylglycerol-lyase
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4.6.1.14 glycosylphosphatidylinositol diacylglycerol-lyase
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4.6.1.15 FAD-AMP lyase (cyclizing)
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4.6.1.16 tRNA-intron lyase
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4.6.1.17 cyclic pyranopterin monophosphate synthase
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4.6.1.18 pancreatic ribonuclease
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4.6.1.19 ribonuclease T2
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4.6.1.20 ribonuclease U2
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4.6.1.21 Enterobacter ribonuclease
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4.6.1.22 Bacillus subtilis ribonuclease
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4.6.1.23 ribotoxin
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4.6.1.24 ribonuclease T1
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4.6.1.25 bacteriophage T4 restriction endoribonuclease RegB
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4.6.1.26 uridylate cyclase
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4.7 carbon-phosphorus lyases
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4.8 Nitrogen-oxygen lyases
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4.98 ATP-independent chelatases
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4.99 Other lyases
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5. Isomerases
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6. Ligases
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7. Translocases
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Enzymes - Callorhinchus milii (elephant shark)