Chromosome and Associated Proteins - Gorilla gorilla gorilla (western lowland gorilla)

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     KO
 Eukaryotic type
   Sister chromatid cohesion proteins
   Meiosis-specific proteins
   Nucleosome assembly factors
   Histone modification proteins
     HATs (histone acetyltransferases)
     HAT complexes
     HDACs (histone deacetylases)
     HDAC complexes
     HMTs (histone methyltransferases)
       HKMTs (histone lysine methyltransferases)
         101134264 ASH1L; histone-lysine N-methyltransferase ASH1L isoform X1
         101134931 DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific
         101139808 EHMT2; histone-lysine N-methyltransferase EHMT2 isoform X2
         101151843 EHMT1; histone-lysine N-methyltransferase EHMT1 isoform X1
         101126515 EZH1; histone-lysine N-methyltransferase EZH1 isoform X1
         101147968 EZH2; histone-lysine N-methyltransferase EZH2 isoform X1
         101129366 KMT2A; histone-lysine N-methyltransferase 2A isoform X1
         101144774 KMT2D; histone-lysine N-methyltransferase 2D isoform X3
         101134599 KMT2C; histone-lysine N-methyltransferase 2C isoform X1
         101139923 KMT2B; histone-lysine N-methyltransferase 2B isoform X1
         101144971 KMT2E; inactive histone-lysine N-methyltransferase 2E
         101130126 NSD1; histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific isoform X1
         101140725 NSD2; histone-lysine N-methyltransferase NSD2 isoform X1
         101127408 NSD3; histone-lysine N-methyltransferase NSD3 isoform X1
         101125370 PRDM2; PR domain zinc finger protein 2 isoform X1
         101143561 MECOM; histone-lysine N-methyltransferase MECOM isoform X6
         101143097 PRDM6; putative histone-lysine N-methyltransferase PRDM6
         101136369 PRDM9; histone-lysine N-methyltransferase PRDM9
         101135995 PRDM7; LOW QUALITY PROTEIN: probable histone-lysine N-methyltransferase PRDM7
         101136822 PRDM8; PR domain zinc finger protein 8
         101149316 ZNF488; LOW QUALITY PROTEIN: zinc finger protein 488
         101126450 PRDM12; PR domain zinc finger protein 12
         101137489 PRDM16; histone-lysine N-methyltransferase PRDM16
         101132140 SETD2; histone-lysine N-methyltransferase SETD2 isoform X3
         101127999 SET domain-containing protein 4
         101124573 SETD6; N-lysine methyltransferase SETD6 isoform X1
         101136477 SETD7; histone-lysine N-methyltransferase SETD7 isoform X1
         101145513 KMT5A; N-lysine methyltransferase KMT5A isoform X1
         101146215 SETDB1; histone-lysine N-methyltransferase SETDB1 isoform X2
         101141713 SETDB2; histone-lysine N-methyltransferase SETDB2 isoform X1
         101150409 histone-lysine N-methyltransferase SETMAR isoform X1
         101147890 SMYD2; N-lysine methyltransferase SMYD2
         101146341 SMYD1; histone-lysine N-methyltransferase SMYD1
         101145998 SMYD3; histone-lysine N-methyltransferase SMYD3 isoform X1
         101146540 SUV39H1; histone-lysine N-methyltransferase SUV39H1
         101126338 SUV39H2; histone-lysine N-methyltransferase SUV39H2 isoform X2
         101139439 KMT5C; histone-lysine N-methyltransferase KMT5C
         101151252 KMT5B; histone-lysine N-methyltransferase KMT5B isoform X1
K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354] 
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356] 
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356] 
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354] 
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354] 
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] 
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354] 
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354] 
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357] 
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357] 
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371] 
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355] 
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367] 
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361] 
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354] 
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-] 
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367] 
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359] 
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364] 
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-] 
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364] 
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361] 
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366] 
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355] 
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
       PRMTs (protein arginine metyltransferases)
     HMT complexes
       COMPASS/SET1 complex
       COMPASS/SET1 complex (yeast)
       MLL-HCF complex
       MLL3/MLL4 complex
       Dot1-containing complex
         101134931 DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific
         101131230 MLLT1; protein ENL isoform X1
         101134723 MLLT3; protein AF-9 isoform X1
         101125850 MLLT10; protein AF-10 isoform X3
         101153932 MLLT6; protein AF-17 isoform X1
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360] 
K15187 MLLT1_3; YEATS domain-containing protein 1/3 
K15187 MLLT1_3; YEATS domain-containing protein 1/3 
K23588 MLLT6_10; protein AF-17/10 
K23588 MLLT6_10; protein AF-17/10 
     Histone demethylases
     Polycomb repressive complex (PRC) and associated proteins
     Sir proteins
     Other histone modification proteins
   Chromosome condensation proteins
   Centromeric chromatin formation proteins
   Heterochromatin formation proteins
   Gene silencing
   Centrosome formation proteins
   Sister chromatid separation proteins
   Chromatin remodeling factors
 
 Prokaryotic type

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Last updated: April 10, 2024