KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:hsa03000]
     03021 Transcription machinery [BR:hsa03021]
     03019 Messenger RNA biogenesis [BR:hsa03019]
     03041 Spliceosome [BR:hsa03041]
     03011 Ribosome [BR:hsa03011]
     03009 Ribosome biogenesis [BR:hsa03009]
     03016 Transfer RNA biogenesis [BR:hsa03016]
     03012 Translation factors [BR:hsa03012]
     03110 Chaperones and folding catalysts [BR:hsa03110]
     04131 Membrane trafficking [BR:hsa04131]
     04121 Ubiquitin system [BR:hsa04121]
     03051 Proteasome [BR:hsa03051]
     03032 DNA replication proteins [BR:hsa03032]
       4998 ORC1; origin recognition complex subunit 1
       4999 ORC2; origin recognition complex subunit 2
       23595 ORC3; origin recognition complex subunit 3
       5000 ORC4; origin recognition complex subunit 4
       5001 ORC5; origin recognition complex subunit 5
       23594 ORC6; origin recognition complex subunit 6
       81620 CDT1; chromatin licensing and DNA replication factor 1
       990 CDC6; cell division cycle 6
       4171 MCM2; minichromosome maintenance complex component 2
       4172 MCM3; minichromosome maintenance complex component 3
       4173 MCM4; minichromosome maintenance complex component 4
       4174 MCM5; minichromosome maintenance complex component 5
       4175 MCM6; minichromosome maintenance complex component 6
       4176 MCM7; minichromosome maintenance complex component 7
       890 CCNA2; cyclin A2
       8900 CCNA1; cyclin A1
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       1017 CDK2; cyclin dependent kinase 2
       8317 CDC7; cell division cycle 7
       9837 GINS1; GINS complex subunit 1
       51659 GINS2; GINS complex subunit 2
       64785 GINS3; GINS complex subunit 3
       84296 GINS4; GINS complex subunit 4
       11073 TOPBP1; DNA topoisomerase II binding protein 1
       9401 RECQL4; RecQ like helicase 4
       8318 CDC45; cell division cycle 45
       84515 MCM8; minichromosome maintenance 8 homologous recombination repair factor
       254394 MCM9; minichromosome maintenance 9 homologous recombination repair factor
       55388 MCM10; minichromosome maintenance 10 replication initiation factor
       92797 HELB; DNA helicase B
       5422 POLA1; DNA polymerase alpha 1, catalytic subunit
       23649 POLA2; DNA polymerase alpha 2, accessory subunit
       5557 PRIM1; DNA primase subunit 1
       5558 PRIM2; DNA primase subunit 2
       5426 POLE; DNA polymerase epsilon, catalytic subunit
       5427 POLE2; DNA polymerase epsilon 2, accessory subunit
       54107 POLE3; DNA polymerase epsilon 3, accessory subunit
       56655 POLE4; DNA polymerase epsilon 4, accessory subunit
       5424 POLD1; DNA polymerase delta 1, catalytic subunit
       5425 POLD2; DNA polymerase delta 2, accessory subunit
       10714 POLD3; DNA polymerase delta 3, accessory subunit
       57804 POLD4; DNA polymerase delta 4, accessory subunit
       5428 POLG; DNA polymerase gamma, catalytic subunit
       11232 POLG2; DNA polymerase gamma 2, accessory subunit
       6117 RPA1; replication protein A1
       6118 RPA2; replication protein A2
       6119 RPA3; replication protein A3
       29935 RPA4; replication protein A4
       5981 RFC1; replication factor C subunit 1
       5984 RFC4; replication factor C subunit 4
       5982 RFC2; replication factor C subunit 2
       5985 RFC5; replication factor C subunit 5
       5983 RFC3; replication factor C subunit 3
       246243 RNASEH1; ribonuclease H1
       10535 RNASEH2A; ribonuclease H2 subunit A
       79621 RNASEH2B; ribonuclease H2 subunit B
       84153 RNASEH2C; ribonuclease H2 subunit C
       5111 PCNA; proliferating cell nuclear antigen
       1763 DNA2; DNA replication helicase/nuclease 2
       2237 FEN1; flap structure-specific endonuclease 1
       9156 EXO1; exonuclease 1
       3978 LIG1; DNA ligase 1
       1786 DNMT1; DNA methyltransferase 1
       1788 DNMT3A; DNA methyltransferase 3 alpha
       1789 DNMT3B; DNA methyltransferase 3 beta
       51053 GMNN; geminin DNA replication inhibitor
       345643 MCIDAS; multiciliate differentiation and DNA synthesis associated cell cycle protein
       891 CCNB1; cyclin B1
       9133 CCNB2; cyclin B2
       85417 CCNB3; cyclin B3
       983 CDK1; cyclin dependent kinase 1
       25913 POT1; protection of telomeres 1
       7013 TERF1; telomeric repeat binding factor 1
       7014 TERF2; telomeric repeat binding factor 2
       26277 TINF2; TERF1 interacting nuclear factor 2
       54386 TERF2IP; TERF2 interacting protein
       65057 ACD; ACD shelterin complex subunit and telomerase recruitment factor
       80169 CTC1; CST telomere replication complex component 1
       79991 STN1; STN1 subunit of CST complex
       100134934 TEN1; TEN1 subunit of CST complex
       23293 SMG6; SMG6 nonsense mediated mRNA decay factor
       23381 SMG5; SMG5 nonsense mediated mRNA decay factor
       7015 TERT; telomerase reverse transcriptase
       7011 TEP1; telomerase associated protein 1
       54433 GAR1; GAR1 ribonucleoprotein
       55651 NHP2; NHP2 ribonucleoprotein
       55505 NOP10; NOP10 ribonucleoprotein
       1736 DKC1; dyskerin pseudouridine synthase 1
       6628 SNRPB; small nuclear ribonucleoprotein polypeptides B and B1
       6632 SNRPD1; small nuclear ribonucleoprotein D1 polypeptide
       6633 SNRPD2; small nuclear ribonucleoprotein D2 polypeptide
       6634 SNRPD3; small nuclear ribonucleoprotein D3 polypeptide
       6635 SNRPE; small nuclear ribonucleoprotein polypeptide E
       6636 SNRPF; small nuclear ribonucleoprotein polypeptide F
       6637 SNRPG; small nuclear ribonucleoprotein polypeptide G
       4361 MRE11; MRE11 homolog, double strand break repair nuclease
       10111 RAD50; RAD50 double strand break repair protein
       4683 NBN; nibrin
       472 ATM; ATM serine/threonine kinase
       7486 WRN; WRN RecQ like helicase
       641 BLM; BLM RecQ like helicase
       5591 PRKDC; protein kinase, DNA-activated, catalytic subunit
       2072 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit
       10038 PARP2; poly(ADP-ribose) polymerase 2
       142 PARP1; poly(ADP-ribose) polymerase 1
       10039 PARP3; poly(ADP-ribose) polymerase family member 3
       143 PARP4; poly(ADP-ribose) polymerase family member 4
       8658 TNKS; tankyrase
       80351 TNKS2; tankyrase 2
       54984 PINX1; PIN2 (TERF1) interacting telomerase inhibitor 1
       51750 RTEL1; regulator of telomere elongation helicase 1
       9894 TELO2; telomere maintenance 2
       55183 RIF1; replication timing regulatory factor 1
       80119 PIF1; PIF1 5'-to-3' DNA helicase
       5813 PURA; purine rich element binding protein A
       29942 PURG; purine rich element binding protein G
       55135 WRAP53; WD repeat containing antisense to TP53
       7150 TOP1; DNA topoisomerase I
       116447 TOP1MT; DNA topoisomerase I mitochondrial
       7155 TOP2B; DNA topoisomerase II beta
       7153 TOP2A; DNA topoisomerase II alpha
       7156 TOP3A; DNA topoisomerase III alpha
       8940 TOP3B; DNA topoisomerase III beta
       6742 SSBP1; single stranded DNA binding protein 1
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K10727 CDT1; chromatin licensing and DNA replication factor 1
K02213 CDC6; cell division control protein 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K10732 GINS1; GINS complex subunit 1
K10733 GINS2; GINS complex subunit 2
K10734 GINS3; GINS complex subunit 3
K10735 GINS4; GINS complex subunit 4
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:3.6.4.12]
K06628 CDC45; cell division control protein 45
K10737 MCM8; DNA helicase MCM8 [EC:3.6.4.12]
K10738 MCM9; DNA helicase MCM9 [EC:3.6.4.12]
K10736 MCM10; minichromosome maintenance protein 10
K15254 HELB; DNA helicase B [EC:3.6.4.12]
K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
K02321 POLA2; DNA polymerase alpha subunit B
K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
K02685 PRI2; DNA primase large subunit
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
K02333 POLG2; DNA polymerase gamma 2
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
K10744 RNASEH2B; ribonuclease H2 subunit B
K10745 RNASEH2C; ribonuclease H2 subunit C
K04802 PCNA; proliferating cell nuclear antigen
K10742 DNA2; DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12]
K04799 FEN1; flap endonuclease-1 [EC:3.-.-.-]
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K10749 GMNN; geminin
K10749 GMNN; geminin
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K11109 POT1; protection of telomeres protein 1
K11110 TERF1; telomeric repeat-binding factor 1
K11111 TERF2; telomeric repeat-binding factor 2
K11112 TINF2; TERF1-interacting nuclear factor 2
K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
K11114 ACD; adrenocortical dysplasia protein
K23311 CTC1; CST complex subunit CTC1
K23312 STN1; CST complex subunit STN1
K23313 TEN1; CST complex subunit TEN1
K11124 SMG6; protein SMG6 [EC:3.1.-.-]
K11125 SMG5; protein SMG5
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K11127 TEP1; telomerase protein component 1
K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
K11086 SNRPB; small nuclear ribonucleoprotein B and B'
K11087 SNRPD1; small nuclear ribonucleoprotein D1
K11096 SNRPD2; small nuclear ribonucleoprotein D2
K11088 SNRPD3; small nuclear ribonucleoprotein D3
K11097 SNRPE; small nuclear ribonucleoprotein E
K11098 SNRPF; small nuclear ribonucleoprotein F
K11099 SNRPG; small nuclear ribonucleoprotein G
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K10900 WRN; werner syndrome ATP-dependent helicase [EC:3.6.4.12]
K10901 BLM; bloom syndrome protein [EC:3.6.4.12]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10798 PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
K10798 PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
K10798 PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
K10798 PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
K10799 TNKS; tankyrase [EC:2.4.2.30]
K10799 TNKS; tankyrase [EC:2.4.2.30]
K11135 PINX1; Pin2-interacting protein X1
K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:3.6.4.12]
K11137 TELO2; telomere length regulation protein
K11138 RIF1; telomere-associated protein RIF1
K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:3.6.4.12]
K21772 PURA; transcriptional activator protein Pur-alpha
K21800 PURG; purine-rich element-binding protein gamma
K23314 WRAP53; telomerase Cajal body protein 1
K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03111 ssb; single-strand DNA-binding protein
     03036 Chromosome and associated proteins [BR:hsa03036]
     03400 DNA repair and recombination proteins [BR:hsa03400]
     03029 Mitochondrial biogenesis [BR:hsa03029]
 
   09183 Protein families: signaling and cellular processes
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

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Last updated: November 14, 2019