KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
     00900 Terpenoid backbone biosynthesis [PATH:hsa00900]
       39 ACAT2; acetyl-CoA acetyltransferase 2
       38 ACAT1; acetyl-CoA acetyltransferase 1
       3157 HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1
       3158 HMGCS2; 3-hydroxy-3-methylglutaryl-CoA synthase 2
       3156 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase
       4598 MVK; mevalonate kinase
       10654 PMVK; phosphomevalonate kinase
       4597 MVD; mevalonate diphosphate decarboxylase
       3422 IDI1; isopentenyl-diphosphate delta isomerase 1
       91734 IDI2; isopentenyl-diphosphate delta isomerase 2
       2224 FDPS; farnesyl diphosphate synthase
       9453 GGPS1; geranylgeranyl diphosphate synthase 1
       23590 PDSS1; decaprenyl diphosphate synthase subunit 1
       57107 PDSS2; decaprenyl diphosphate synthase subunit 2
       79947 DHDDS; dehydrodolichyl diphosphate synthase subunit
       116150 NUS1; NUS1 dehydrodolichyl diphosphate synthase subunit
       2339 FNTA; farnesyltransferase, CAAX box, subunit alpha
       2342 FNTB; farnesyltransferase, CAAX box, subunit beta
       100529261 CHURC1-FNTB; CHURC1-FNTB readthrough
       9986 RCE1; Ras converting CAAX endopeptidase 1
       10269 ZMPSTE24; zinc metallopeptidase STE24
       23463 ICMT; isoprenylcysteine carboxyl methyltransferase
       51449 PCYOX1; prenylcysteine oxidase 1
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
K00869 MVK; mevalonate kinase [EC:2.7.1.36]
K13273 PMVK; phosphomevalonate kinase [EC:2.7.4.2]
K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33]
K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K00804 GGPS1; geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]
K12504 PDSS1; decaprenyl-diphosphate synthase subunit 1 [EC:2.5.1.91]
K12505 PDSS2; decaprenyl-diphosphate synthase subunit 2 [EC:2.5.1.91]
K11778 DHDDS; ditrans,polycis-polyprenyl diphosphate synthase [EC:2.5.1.87]
K19177 NUS1; dehydrodolichyl diphosphate syntase complex subunit NUS1 [EC:2.5.1.87]
K05955 FNTA; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59]
K05954 FNTB; protein farnesyltransferase subunit beta [EC:2.5.1.58]
K05954 FNTB; protein farnesyltransferase subunit beta [EC:2.5.1.58]
K08658 RCE1; intramembrane prenyl-peptidase [EC:3.4.26.1]
K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
K00587 ICMT; protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]
K05906 PCYOX1; prenylcysteine oxidase / farnesylcysteine lyase [EC:1.8.3.5 1.8.3.6]
     00902 Monoterpenoid biosynthesis
     00909 Sesquiterpenoid and triterpenoid biosynthesis
     00904 Diterpenoid biosynthesis
     00906 Carotenoid biosynthesis
     00905 Brassinosteroid biosynthesis
     00981 Insect hormone biosynthesis
     00908 Zeatin biosynthesis
     00903 Limonene degradation
     00907 Pinene, camphor and geraniol degradation
     01052 Type I polyketide structures
     00522 Biosynthesis of 12-, 14- and 16-membered macrolides
     01051 Biosynthesis of ansamycins
     01059 Biosynthesis of enediyne antibiotics
     01056 Biosynthesis of type II polyketide backbone
     01057 Biosynthesis of type II polyketide products
     00253 Tetracycline biosynthesis
     00523 Polyketide sugar unit biosynthesis
     01054 Nonribosomal peptide structures
     01053 Biosynthesis of siderophore group nonribosomal peptides
     01055 Biosynthesis of vancomycin group antibiotics
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
     05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
       6513 SLC2A1; solute carrier family 2 member 1
       8829 NRP1; neuropilin 1
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       8295 TRRAP; transformation/transcription domain associated protein
       10524 KAT5; lysine acetyltransferase 5
       894 CCND2; cyclin D2
       3683 ITGAL; integrin subunit alpha L
       3689 ITGB2; integrin subunit beta 2
       3383 ICAM1; intercellular adhesion molecule 1
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       920 CD4; CD4 molecule
       7094 TLN1; talin 1
       83660 TLN2; talin 2
       8498 RANBP3; RAN binding protein 3
       5901 RAN; RAN, member RAS oncogene family
       7514 XPO1; exportin 1
       811 CALR; calreticulin
       821 CANX; calnexin
       5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
       5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
       4772 NFATC1; nuclear factor of activated T cells 1
       4773 NFATC2; nuclear factor of activated T cells 2
       4775 NFATC3; nuclear factor of activated T cells 3
       4776 NFATC4; nuclear factor of activated T cells 4
       3560 IL2RB; interleukin 2 receptor subunit beta
       3561 IL2RG; interleukin 2 receptor subunit gamma
       3716 JAK1; Janus kinase 1
       3718 JAK3; Janus kinase 3
       6776 STAT5A; signal transducer and activator of transcription 5A
       6777 STAT5B; signal transducer and activator of transcription 5B
       3558 IL2; interleukin 2
       3105 HLA-A; major histocompatibility complex, class I, A
       3106 HLA-B; major histocompatibility complex, class I, B
       3107 HLA-C; major histocompatibility complex, class I, C
       3134 HLA-F; major histocompatibility complex, class I, F
       3135 HLA-G; major histocompatibility complex, class I, G
       3133 HLA-E; major histocompatibility complex, class I, E
       567 B2M; beta-2-microglobulin
       2224 FDPS; farnesyl diphosphate synthase
       7416 VDAC1; voltage dependent anion channel 1
       291 SLC25A4; solute carrier family 25 member 4
       292 SLC25A5; solute carrier family 25 member 5
       293 SLC25A6; solute carrier family 25 member 6
       83447 SLC25A31; solute carrier family 25 member 31
       7417 VDAC2; voltage dependent anion channel 2
       7419 VDAC3; voltage dependent anion channel 3
       706 TSPO; translocator protein
       55697 VAC14; VAC14 component of PIKFYVE complex
       5902 RANBP1; RAN binding protein 1
       8379 MAD1L1; mitotic arrest deficient 1 like 1
       4085 MAD2L1; mitotic arrest deficient 2 like 1
       701 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
       9184 BUB3; BUB3 mitotic checkpoint protein
       64682 ANAPC1; anaphase promoting complex subunit 1
       29882 ANAPC2; anaphase promoting complex subunit 2
       996 CDC27; cell division cycle 27
       29945 ANAPC4; anaphase promoting complex subunit 4
       51433 ANAPC5; anaphase promoting complex subunit 5
       8881 CDC16; cell division cycle 16
       51434 ANAPC7; anaphase promoting complex subunit 7
       8697 CDC23; cell division cycle 23
       10393 ANAPC10; anaphase promoting complex subunit 10
       51529 ANAPC11; anaphase promoting complex subunit 11
       246184 CDC26; cell division cycle 26
       25847 ANAPC13; anaphase promoting complex subunit 13
       25906 ANAPC15; anaphase promoting complex subunit 15
       119504 ANAPC16; anaphase promoting complex subunit 16
       991 CDC20; cell division cycle 20
       9232 PTTG1; PTTG1 regulator of sister chromatid separation, securin
       10744 PTTG2; pituitary tumor-transforming 2
       9700 ESPL1; extra spindle pole bodies like 1, separase
       9133 CCNB2; cyclin B2
       1030 CDKN2B; cyclin dependent kinase inhibitor 2B
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       1019 CDK4; cyclin dependent kinase 4
       595 CCND1; cyclin D1
       896 CCND3; cyclin D3
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       890 CCNA2; cyclin A2
       8900 CCNA1; cyclin A1
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       1017 CDK2; cyclin dependent kinase 2
       5925 RB1; RB transcriptional corepressor 1
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       472 ATM; ATM serine/threonine kinase
       545 ATR; ATR serine/threonine kinase
       1111 CHEK1; checkpoint kinase 1
       11200 CHEK2; checkpoint kinase 2
       7157 TP53; tumor protein p53
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       1739 DLG1; discs large MAGUK scaffold protein 1
       5728 PTEN; phosphatase and tensin homolog
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
       6416 MAP2K4; mitogen-activated protein kinase kinase 4
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       4316 MMP7; matrix metallopeptidase 7
       3554 IL1R1; interleukin 1 receptor type 1
       7850 IL1R2; interleukin 1 receptor type 2
       915 CD3D; CD3 delta subunit of T-cell receptor complex
       916 CD3E; CD3 epsilon subunit of T-cell receptor complex
       917 CD3G; CD3 gamma subunit of T-cell receptor complex
       4215 MAP3K3; mitogen-activated protein kinase kinase kinase 3
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       2874 GPS2; G protein pathway suppressor 2
       4055 LTBR; lymphotoxin beta receptor
       958 CD40; CD40 molecule
       115650 TNFRSF13C; TNF receptor superfamily member 13C
       9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
       5971 RELB; RELB proto-oncogene, NF-kB subunit
       4791 NFKB2; nuclear factor kappa B subunit 2
       7538 ZFP36; ZFP36 ring finger protein
       3559 IL2RA; interleukin 2 receptor subunit alpha
       3600 IL15; interleukin 15
       3601 IL15RA; interleukin 15 receptor subunit alpha
       3569 IL6; interleukin 6
       1437 CSF2; colony stimulating factor 2
       4049 LTA; lymphotoxin alpha
       598 BCL2L1; BCL2 like 1
       331 XIAP; X-linked inhibitor of apoptosis
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       7046 TGFBR1; transforming growth factor beta receptor 1
       7048 TGFBR2; transforming growth factor beta receptor 2
       4087 SMAD2; SMAD family member 2
       4088 SMAD3; SMAD family member 3
       4089 SMAD4; SMAD family member 4
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       4801 NFYB; nuclear transcription factor Y subunit beta
       3108 HLA-DMA; major histocompatibility complex, class II, DM alpha
       3109 HLA-DMB; major histocompatibility complex, class II, DM beta
       3111 HLA-DOA; major histocompatibility complex, class II, DO alpha
       3112 HLA-DOB; major histocompatibility complex, class II, DO beta
       3113 HLA-DPA1; major histocompatibility complex, class II, DP alpha 1
       3115 HLA-DPB1; major histocompatibility complex, class II, DP beta 1
       3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1
       3118 HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2
       3119 HLA-DQB1; major histocompatibility complex, class II, DQ beta 1
       3122 HLA-DRA; major histocompatibility complex, class II, DR alpha
       3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1
       3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3
       3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4
       3127 HLA-DRB5; major histocompatibility complex, class II, DR beta 5
       6722 SRF; serum response factor
       2005 ELK4; ETS transcription factor ELK4
       2002 ELK1; ETS transcription factor ELK1
       6688 SPI1; Spi-1 proto-oncogene
       2113 ETS1; ETS proto-oncogene 1, transcription factor
       2114 ETS2; ETS proto-oncogene 2, transcription factor
       387332 TBPL2; TATA-box binding protein like 2
       9519 TBPL1; TATA-box binding protein like 1
       6908 TBP; TATA-box binding protein
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       1958 EGR1; early growth response 1
       8061 FOSL1; FOS like 1, AP-1 transcription factor subunit
       1959 EGR2; early growth response 2
       1385 CREB1; cAMP responsive element binding protein 1
       10488 CREB3; cAMP responsive element binding protein 3
       90993 CREB3L1; cAMP responsive element binding protein 3 like 1
       64764 CREB3L2; cAMP responsive element binding protein 3 like 2
       84699 CREB3L3; cAMP responsive element binding protein 3 like 3
       148327 CREB3L4; cAMP responsive element binding protein 3 like 4
       1386 ATF2; activating transcription factor 2
       468 ATF4; activating transcription factor 4
       9586 CREB5; cAMP responsive element binding protein 5
       1388 ATF6B; activating transcription factor 6 beta
       23373 CRTC1; CREB regulated transcription coactivator 1
       200186 CRTC2; CREB regulated transcription coactivator 2
       64784 CRTC3; CREB regulated transcription coactivator 3
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       8850 KAT2B; lysine acetyltransferase 2B
       2648 KAT2A; lysine acetyltransferase 2A
       6929 TCF3; transcription factor 3
       5423 POLB; DNA polymerase beta
       3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
       581 BAX; BCL2 associated X, apoptosis regulator
       1031 CDKN2C; cyclin dependent kinase inhibitor 2C
       7015 TERT; telomerase reverse transcriptase
       4487 MSX1; msh homeobox 1
       4488 MSX2; msh homeobox 2
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1; neuropilin 1
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; G1/S-specific cyclin-D2
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K06490 ICAM1; intercellular adhesion molecule 1
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06454 CD4; T-cell surface glycoprotein CD4
K06271 TLN; talin
K06271 TLN; talin
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1; exportin-1
K08057 CALR; calreticulin
K08054 CANX; calnexin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 TSPO; translocator protein
K15305 VAC14; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K25228 APC15; anaphase-promoting complex subunit 15
K25229 APC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K12076 DLG1; disks large protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K04386 IL1R1; interleukin 1 receptor type I
K04387 IL1R2; interleukin 1 receptor type II
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K04421 MAP3K3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K15307 GPS2; G protein pathway suppressor 2
K03159 TNFRSF3; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K15308 TTP; tristetraprolin
K05068 IL2RA; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K05468 LTA; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08065 NFYB; nuclear transcription Y subunit beta
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K04378 SRF; serum response factor
K04376 ELK4; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS1; C-ets-1
K21932 ETS2; C-ets-2
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K04502 FOSL1; fos-like antigen 1
K12496 EGR2; early growth response protein 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K15309 CRTC1; CREB-regulated transcription coactivator 1
K16333 CRTC2; CREB-regulated transcription coactivator 2
K16334 CRTC3; CREB-regulated transcription coactivator 3
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K02159 BAX; apoptosis regulator BAX
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09341 MSX; homeobox protein MSX
K09341 MSX; homeobox protein MSX
     05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
     05161 Hepatitis B [PATH:hsa05161]
     05160 Hepatitis C [PATH:hsa05160]
     05171 Coronavirus disease - COVID-19 [PATH:hsa05171]
     05164 Influenza A [PATH:hsa05164]
       23430 TPSD1; tryptase delta 1
       7177 TPSAB1; tryptase alpha/beta 1
       64499 TPSB2; tryptase beta 2
       5340 PLG; plasminogen
       5646 PRSS3; serine protease 3
       5645 PRSS2; serine protease 2
       5644 PRSS1; serine protease 1
       7113 TMPRSS2; transmembrane serine protease 2
       56649 TMPRSS4; transmembrane serine protease 4
       9407 TMPRSS11D; transmembrane serine protease 11D
       5579 PRKCB; protein kinase C beta
       4938 OAS1; 2'-5'-oligoadenylate synthetase 1
       4939 OAS2; 2'-5'-oligoadenylate synthetase 2
       4940 OAS3; 2'-5'-oligoadenylate synthetase 3
       6041 RNASEL; ribonuclease L
       3337 DNAJB1; DnaJ heat shock protein family (Hsp40) member B1
       5611 DNAJC3; DnaJ heat shock protein family (Hsp40) member C3
       5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
       1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
       7706 TRIM25; tripartite motif containing 25
       23586 RIGI; RNA sensor RIG-I
       64135 IFIH1; interferon induced with helicase C domain 1
       79671 NLRX1; NLR family member X1
       57506 MAVS; mitochondrial antiviral signaling protein
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4793 NFKBIB; NFKB inhibitor beta
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       10241 CALCOCO2; calcium binding and coiled-coil domain 2
       7098 TLR3; toll like receptor 3
       148022 TICAM1; TIR domain containing adaptor molecule 1
       7187 TRAF3; TNF receptor associated factor 3
       29110 TBK1; TANK binding kinase 1
       9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
       3661 IRF3; interferon regulatory factor 3
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       7099 TLR4; toll like receptor 4
       51284 TLR7; toll like receptor 7
       4615 MYD88; MYD88 innate immune signal transduction adaptor
       51135 IRAK4; interleukin 1 receptor associated kinase 4
       3665 IRF7; interferon regulatory factor 7
       3552 IL1A; interleukin 1 alpha
       3553 IL1B; interleukin 1 beta
       3569 IL6; interleukin 6
       3592 IL12A; interleukin 12A
       3593 IL12B; interleukin 12B
       7124 TNF; tumor necrosis factor
       3576 CXCL8; C-X-C motif chemokine ligand 8
       6347 CCL2; C-C motif chemokine ligand 2
       6352 CCL5; C-C motif chemokine ligand 5
       3627 CXCL10; C-X-C motif chemokine ligand 10
       3383 ICAM1; intercellular adhesion molecule 1
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3456 IFNB1; interferon beta 1
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       3716 JAK1; Janus kinase 1
       7297 TYK2; tyrosine kinase 2
       9021 SOCS3; suppressor of cytokine signaling 3
       6772 STAT1; signal transducer and activator of transcription 1
       6773 STAT2; signal transducer and activator of transcription 2
       10379 IRF9; interferon regulatory factor 9
       4599 MX1; MX dynamin like GTPase 1
       4600 MX2; MX dynamin like GTPase 2
       103 ADAR; adenosine deaminase RNA specific
       5371 PML; PML nuclear body scaffold
       3458 IFNG; interferon gamma
       3459 IFNGR1; interferon gamma receptor 1
       3460 IFNGR2; interferon gamma receptor 2
       3717 JAK2; Janus kinase 2
       4261 CIITA; class II major histocompatibility complex transactivator
       3108 HLA-DMA; major histocompatibility complex, class II, DM alpha
       3109 HLA-DMB; major histocompatibility complex, class II, DM beta
       3111 HLA-DOA; major histocompatibility complex, class II, DO alpha
       3112 HLA-DOB; major histocompatibility complex, class II, DO beta
       3113 HLA-DPA1; major histocompatibility complex, class II, DP alpha 1
       3115 HLA-DPB1; major histocompatibility complex, class II, DP beta 1
       3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1
       3118 HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2
       3119 HLA-DQB1; major histocompatibility complex, class II, DQ beta 1
       3122 HLA-DRA; major histocompatibility complex, class II, DR alpha
       3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1
       3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3
       3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4
       3127 HLA-DRB5; major histocompatibility complex, class II, DR beta 5
       114548 NLRP3; NLR family pyrin domain containing 3
       29108 PYCARD; PYD and CARD domain containing
       834 CASP1; caspase 1
       3606 IL18; interleukin 18
       90865 IL33; interleukin 33
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       896 CCND3; cyclin D3
       1019 CDK4; cyclin dependent kinase 4
       1021 CDK6; cyclin dependent kinase 6
       8743 TNFSF10; TNF superfamily member 10
       8797 TNFRSF10A; TNF receptor superfamily member 10a
       8795 TNFRSF10B; TNF receptor superfamily member 10b
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8717 TRADD; TNFRSF1A associated via death domain
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       7416 VDAC1; voltage dependent anion channel 1
       291 SLC25A4; solute carrier family 25 member 4
       292 SLC25A5; solute carrier family 25 member 5
       293 SLC25A6; solute carrier family 25 member 6
       83447 SLC25A31; solute carrier family 25 member 31
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
       836 CASP3; caspase 3
       10898 CPSF4; cleavage and polyadenylation specific factor 4
       642843 CPSF4L; cleavage and polyadenylation specific factor 4 like
       8106 PABPN1; poly(A) binding protein nuclear 1
       390748 PABPN1L; PABPN1 like, cytoplasmic
       100529063 BCL2L2-PABPN1; BCL2L2-PABPN1 readthrough
       10482 NXF1; nuclear RNA export factor 1
       56001 NXF2; nuclear RNA export factor 2
       728343 NXF2B; nuclear RNA export factor 2B
       56000 NXF3; nuclear RNA export factor 3
       29107 NXT1; nuclear transport factor 2 like export factor 1
       55916 NXT2; nuclear transport factor 2 like export factor 2
       11100 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U like 1
       8480 RAE1; ribonucleic acid export 1
       4928 NUP98; nucleoporin 98 and 96 precursor
       91543 RSAD2; radical S-adenosyl methionine domain containing 2
       2224 FDPS; farnesyl diphosphate synthase
       5578 PRKCA; protein kinase C alpha
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       8766 RAB11A; RAB11A, member RAS oncogene family
       9230 RAB11B; RAB11B, member RAS oncogene family
       7514 XPO1; exportin 1
       3836 KPNA1; karyopherin subunit alpha 1
       3838 KPNA2; karyopherin subunit alpha 2
       402569 KPNA7; karyopherin subunit alpha 7
       23633 KPNA6; karyopherin subunit alpha 6
       3841 KPNA5; karyopherin subunit alpha 5
K01340 E3.4.21.59; tryptase [EC:3.4.21.59]
K01340 E3.4.21.59; tryptase [EC:3.4.21.59]
K01340 E3.4.21.59; tryptase [EC:3.4.21.59]
K01315 PLG; plasminogen [EC:3.4.21.7]
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4]
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4]
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4]
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09635 TMPRSS4; transmembrane protease serine 4 [EC:3.4.21.-]
K09641 TMPRSS11D; transmembrane protease serine 11D [EC:3.4.21.-]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K09507 DNAJB1; DnaJ homolog subfamily B member 1
K09523 DNAJC3; DnaJ homolog subfamily C member 3
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
K12646 DDX58; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12653 NLRX1; NLR family member X1
K12648 MAVS; mitochondrial antiviral-signaling protein
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K21348 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2
K05401 TLR3; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K10160 TLR4; toll-like receptor 4
K05404 TLR7; toll-like receptor 7
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K09447 IRF7; interferon regulatory factor 7
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF; tumor necrosis factor superfamily, member 2
K10030 IL8; interleukin 8
K14624 CCL2; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K12671 CXCL10; C-X-C motif chemokine 10
K06490 ICAM1; intercellular adhesion molecule 1
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04696 SOCS3; suppressor of cytokine signaling 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9; interferon regulatory factor 9
K14754 MX; interferon-induced GTP-binding protein Mx
K14754 MX; interferon-induced GTP-binding protein Mx
K12968 ADAR; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K04687 IFNG; interferon gamma
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18; interleukin 18
K12967 IL33; interleukin 33
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
K14396 PABPN1; polyadenylate-binding protein 2
K14396 PABPN1; polyadenylate-binding protein 2
K14396 PABPN1; polyadenylate-binding protein 2
K14284 NXF; nuclear RNA export factor
K14284 NXF; nuclear RNA export factor
K14284 NXF; nuclear RNA export factor
K14284 NXF; nuclear RNA export factor
K14285 NXT1_2; NTF2-related export protein 1/2
K14285 NXT1_2; NTF2-related export protein 1/2
K15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1
K14298 RAE1; mRNA export factor
K14297 NUP98; nuclear pore complex protein Nup98-Nup96
K15045 RSAD2; radical S-adenosyl methionine domain-containing protein 2
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K07904 RAB11A; Ras-related protein Rab-11A
K07905 RAB11B; Ras-related protein Rab-11B
K14290 XPO1; exportin-1
K23940 KPNA1; importin subunit alpha-5
K15043 KPNA2_7; importin subunit alpha-1/8
K15043 KPNA2_7; importin subunit alpha-1/8
K15042 KPNA5_6; importin subunit alpha-6/7
K15042 KPNA5_6; importin subunit alpha-6/7
     05162 Measles [PATH:hsa05162]
     05168 Herpes simplex virus 1 infection [PATH:hsa05168]
     05163 Human cytomegalovirus infection [PATH:hsa05163]
     05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
     05169 Epstein-Barr virus infection [PATH:hsa05169]
     05165 Human papillomavirus infection [PATH:hsa05165]
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
     01000 Enzymes [BR:hsa01000]
     01001 Protein kinases [BR:hsa01001]
     01009 Protein phosphatases and associated proteins [BR:hsa01009]
     01002 Peptidases and inhibitors [BR:hsa01002]
     01003 Glycosyltransferases [BR:hsa01003]
     01005 Lipopolysaccharide biosynthesis proteins
     01011 Peptidoglycan biosynthesis and degradation proteins
     01004 Lipid biosynthesis proteins [BR:hsa01004]
     01008 Polyketide biosynthesis proteins
     01006 Prenyltransferases [BR:hsa01006]
       2224 FDPS; farnesyl diphosphate synthase
       9453 GGPS1; geranylgeranyl diphosphate synthase 1
       23590 PDSS1; decaprenyl diphosphate synthase subunit 1
       57107 PDSS2; decaprenyl diphosphate synthase subunit 2
       79947 DHDDS; dehydrodolichyl diphosphate synthase subunit
       2222 FDFT1; farnesyl-diphosphate farnesyltransferase 1
       54802 TRIT1; tRNA isopentenyltransferase 1
       27235 COQ2; coenzyme Q2, polyprenyltransferase
       1352 COX10; cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
       2339 FNTA; farnesyltransferase, CAAX box, subunit alpha
       2342 FNTB; farnesyltransferase, CAAX box, subunit beta
       100529261 CHURC1-FNTB; CHURC1-FNTB readthrough
       5229 PGGT1B; protein geranylgeranyltransferase type I subunit beta
       5875 RABGGTA; Rab geranylgeranyltransferase subunit alpha
       5876 RABGGTB; Rab geranylgeranyltransferase subunit beta
       1121 CHM; CHM Rab escort protein
       1122 CHML; CHM like Rab escort protein
       375743 PTAR1; protein prenyltransferase alpha subunit repeat containing 1
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K00804 GGPS1; geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]
K12504 PDSS1; decaprenyl-diphosphate synthase subunit 1 [EC:2.5.1.91]
K12505 PDSS2; decaprenyl-diphosphate synthase subunit 2 [EC:2.5.1.91]
K11778 DHDDS; ditrans,polycis-polyprenyl diphosphate synthase [EC:2.5.1.87]
K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
K06125 COQ2; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
K02257 COX10; heme o synthase [EC:2.5.1.141]
K05955 FNTA; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59]
K05954 FNTB; protein farnesyltransferase subunit beta [EC:2.5.1.58]
K05954 FNTB; protein farnesyltransferase subunit beta [EC:2.5.1.58]
K11713 PGTB1; geranylgeranyl transferase type-1 subunit beta [EC:2.5.1.59]
K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
K23460 CHM; Rab proteins geranylgeranyltransferase component A
K23460 CHM; Rab proteins geranylgeranyltransferase component A
K14137 PTAR1; protein prenyltransferase alpha subunit repeat containing protein 1
     01007 Amino acid related enzymes [BR:hsa01007]
     00199 Cytochrome P450 [BR:hsa00199]
     00194 Photosynthesis proteins
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 22, 2024