KEGG Orthology (KO) - Homo sapiens (human)

[ Brite menu | Download htext | Download json | Help ]
Search

1st Level  2nd Level  3rd Level  4th Level 

     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:hsa04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:hsa04012]
     04014 Ras signaling pathway [PATH:hsa04014]
     04015 Rap1 signaling pathway [PATH:hsa04015]
     04310 Wnt signaling pathway [PATH:hsa04310]
     04330 Notch signaling pathway [PATH:hsa04330]
     04340 Hedgehog signaling pathway [PATH:hsa04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:hsa04350]
     04390 Hippo signaling pathway [PATH:hsa04390]
       286204 CRB2; crumbs cell polarity complex component 2
       23418 CRB1; crumbs cell polarity complex component 1
       56288 PARD3; par-3 family cell polarity regulator
       50855 PARD6A; par-6 family cell polarity regulator alpha
       84552 PARD6G; par-6 family cell polarity regulator gamma
       84612 PARD6B; par-6 family cell polarity regulator beta
       5590 PRKCZ; protein kinase C zeta
       5584 PRKCI; protein kinase C iota
       10207 PATJ; PATJ crumbs cell polarity complex component
       64398 PALS1; protein associated with LIN7 1, MAGUK p55 family member
       154796 AMOT; angiomotin
       10413 YAP1; Yes1 associated transcriptional regulator
       25937 WWTR1; WW domain containing transcription regulator 1
       999 CDH1; cadherin 1
       8994 LIMD1; LIM domain containing 1
       84962 AJUBA; ajuba LIM protein
       126374 WTIP; WT1 interacting protein
       4771 NF2; NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
       23286 WWC1; WW and C2 domain containing 1
       79981 FRMD1; FERM domain containing 1
       122786 FRMD6; FERM domain containing 6
       60485 SAV1; salvador family WW domain containing protein 1
       6788 STK3; serine/threonine kinase 3
       166824 RASSF6; Ras association domain family member 6
       11186 RASSF1; Ras association domain family member 1
       5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
       5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
       5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
       5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
       5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
       5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
       5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
       55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
       26524 LATS2; large tumor suppressor kinase 2
       9113 LATS1; large tumor suppressor kinase 1
       55233 MOB1A; MOB kinase activator 1A
       92597 MOB1B; MOB kinase activator 1B
       5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
       5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
       5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
       7159 TP53BP2; tumor protein p53 binding protein 2
       3993 LLGL2; LLGL scribble cell polarity complex component 2
       3996 LLGL1; LLGL scribble cell polarity complex component 1
       23513 SCRIB; scribble planar cell polarity protein
       1739 DLG1; discs large MAGUK scaffold protein 1
       1740 DLG2; discs large MAGUK scaffold protein 2
       1741 DLG3; discs large MAGUK scaffold protein 3
       1742 DLG4; discs large MAGUK scaffold protein 4
       9231 DLG5; discs large MAGUK scaffold protein 5
       1453 CSNK1D; casein kinase 1 delta
       1454 CSNK1E; casein kinase 1 epsilon
       102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
       8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       23291 FBXW11; F-box and WD repeat domain containing 11
       7161 TP73; tumor protein p73
       27113 BBC3; BCL2 binding component 3
       7003 TEAD1; TEA domain transcription factor 1
       7004 TEAD4; TEA domain transcription factor 4
       7005 TEAD3; TEA domain transcription factor 3
       8463 TEAD2; TEA domain transcription factor 2
       1490 CCN2; cellular communication network factor 2
       2736 GLI2; GLI family zinc finger 2
       374 AREG; amphiregulin
       332 BIRC5; baculoviral IAP repeat containing 5
       174 AFP; alpha fetoprotein
       3689 ITGB2; integrin subunit beta 2
       2246 FGF1; fibroblast growth factor 1
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       7046 TGFBR1; transforming growth factor beta receptor 1
       7048 TGFBR2; transforming growth factor beta receptor 2
       4092 SMAD7; SMAD family member 7
       4087 SMAD2; SMAD family member 2
       4088 SMAD3; SMAD family member 3
       4089 SMAD4; SMAD family member 4
       5054 SERPINE1; serpin family E member 1
       650 BMP2; bone morphogenetic protein 2
       652 BMP4; bone morphogenetic protein 4
       653 BMP5; bone morphogenetic protein 5
       654 BMP6; bone morphogenetic protein 6
       655 BMP7; bone morphogenetic protein 7
       656 BMP8B; bone morphogenetic protein 8b
       353500 BMP8A; bone morphogenetic protein 8a
       8200 GDF5; growth differentiation factor 5
       392255 GDF6; growth differentiation factor 6
       151449 GDF7; growth differentiation factor 7
       268 AMH; anti-Mullerian hormone
       657 BMPR1A; bone morphogenetic protein receptor type 1A
       658 BMPR1B; bone morphogenetic protein receptor type 1B
       659 BMPR2; bone morphogenetic protein receptor type 2
       4086 SMAD1; SMAD family member 1
       3397 ID1; inhibitor of DNA binding 1
       3398 ID2; inhibitor of DNA binding 2
       7471 WNT1; Wnt family member 1
       7472 WNT2; Wnt family member 2
       7482 WNT2B; Wnt family member 2B
       7473 WNT3; Wnt family member 3
       89780 WNT3A; Wnt family member 3A
       54361 WNT4; Wnt family member 4
       7474 WNT5A; Wnt family member 5A
       81029 WNT5B; Wnt family member 5B
       7475 WNT6; Wnt family member 6
       7476 WNT7A; Wnt family member 7A
       7477 WNT7B; Wnt family member 7B
       7478 WNT8A; Wnt family member 8A
       7479 WNT8B; Wnt family member 8B
       7483 WNT9A; Wnt family member 9A
       7484 WNT9B; Wnt family member 9B
       7480 WNT10B; Wnt family member 10B
       80326 WNT10A; Wnt family member 10A
       7481 WNT11; Wnt family member 11
       51384 WNT16; Wnt family member 16
       8321 FZD1; frizzled class receptor 1
       8324 FZD7; frizzled class receptor 7
       2535 FZD2; frizzled class receptor 2
       7976 FZD3; frizzled class receptor 3
       8322 FZD4; frizzled class receptor 4
       7855 FZD5; frizzled class receptor 5
       8325 FZD8; frizzled class receptor 8
       8323 FZD6; frizzled class receptor 6
       11211 FZD10; frizzled class receptor 10
       8326 FZD9; frizzled class receptor 9
       1857 DVL3; dishevelled segment polarity protein 3
       1856 DVL2; dishevelled segment polarity protein 2
       1855 DVL1; dishevelled segment polarity protein 1
       7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       2932 GSK3B; glycogen synthase kinase 3 beta
       1499 CTNNB1; catenin beta 1
       324 APC; APC regulator of WNT signaling pathway
       10297 APC2; APC regulator of WNT signaling pathway 2
       8312 AXIN1; axin 1
       8313 AXIN2; axin 2
       85407 NKD1; NKD inhibitor of WNT signaling pathway 1
       85409 NKD2; NKD inhibitor of WNT signaling pathway 2
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       595 CCND1; cyclin D1
       894 CCND2; cyclin D2
       896 CCND3; cyclin D3
       6657 SOX2; SRY-box transcription factor 2
       6591 SNAI2; snail family transcriptional repressor 2
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       29119 CTNNA3; catenin alpha 3
       1495 CTNNA1; catenin alpha 1
       1496 CTNNA2; catenin alpha 2
K16681 CRB; protein crumbs
K16681 CRB; protein crumbs
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06092 INADL; InaD-like protein
K06091 MPP5; MAGUK p55 subfamily member 5
K16819 AMOT; angiomotin
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K16686 SAV1; scaffold protein salvador
K04412 STK3; serine/threonine kinase 3
K09854 RASSF6; Ras association domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16823 TP53BP2; apoptosis-stimulating of p53 protein 2
K06094 LLGL; lethal(2) giant larvae protein
K06094 LLGL; lethal(2) giant larvae protein
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K11828 DLG4; discs large protein 4
K24050 DLG5; discs large protein 5
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10148 TP73; tumor protein p73
K10132 BBC3; Bcl-2-binding component 3
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K16798 GLI2; zinc finger protein GLI2
K09782 AREG; amphiregulin
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16144 AFP; alpha-fetoprotein
K06464 ITGB2; integrin beta 2
K18496 FGF1; fibroblast growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03982 SERPINE1; plasminogen activator inhibitor 1
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16796 SOX2; transcription factor SOX2 (SOX group B)
K05706 SNAI2; snail 2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
     04370 VEGF signaling pathway [PATH:hsa04370]
     04371 Apelin signaling pathway [PATH:hsa04371]
     04630 JAK-STAT signaling pathway [PATH:hsa04630]
     04064 NF-kappa B signaling pathway [PATH:hsa04064]
     04668 TNF signaling pathway [PATH:hsa04668]
     04066 HIF-1 signaling pathway [PATH:hsa04066]
     04068 FoxO signaling pathway [PATH:hsa04068]
     04020 Calcium signaling pathway [PATH:hsa04020]
     04070 Phosphatidylinositol signaling system [PATH:hsa04070]
     04072 Phospholipase D signaling pathway [PATH:hsa04072]
     04071 Sphingolipid signaling pathway [PATH:hsa04071]
     04024 cAMP signaling pathway [PATH:hsa04024]
     04022 cGMP-PKG signaling pathway [PATH:hsa04022]
     04151 PI3K-Akt signaling pathway [PATH:hsa04151]
     04152 AMPK signaling pathway [PATH:hsa04152]
     04150 mTOR signaling pathway [PATH:hsa04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:hsa04110]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:hsa04114]
     04210 Apoptosis [PATH:hsa04210]
       8743 TNFSF10; TNF superfamily member 10
       8797 TNFRSF10A; TNF receptor superfamily member 10a
       8795 TNFRSF10B; TNF receptor superfamily member 10b
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       8772 FADD; Fas associated via death domain
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8717 TRADD; TNFRSF1A associated via death domain
       8837 CFLAR; CASP8 and FADD like apoptosis regulator
       841 CASP8; caspase 8
       843 CASP10; caspase 10
       839 CASP6; caspase 6
       836 CASP3; caspase 3
       840 CASP7; caspase 7
       637 BID; BH3 interacting domain death agonist
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       56616 DIABLO; diablo IAP-binding mitochondrial protein
       5414 SEPTIN4; septin 4
       27429 HTRA2; HtrA serine peptidase 2
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
       5551 PRF1; perforin 1
       3002 GZMB; granzyme B
       10376 TUBA1B; tubulin alpha 1b
       7277 TUBA4A; tubulin alpha 4a
       7278 TUBA3C; tubulin alpha 3c
       7846 TUBA1A; tubulin alpha 1a
       84790 TUBA1C; tubulin alpha 1c
       51807 TUBA8; tubulin alpha 8
       112714 TUBA3E; tubulin alpha 3e
       113457 TUBA3D; tubulin alpha 3d
       79861 TUBAL3; tubulin alpha like 3
       4170 MCL1; MCL1 apoptosis regulator, BCL2 family member
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       6709 SPTAN1; spectrin alpha, non-erythrocytic 1
       4000 LMNA; lamin A/C
       4001 LMNB1; lamin B1
       84823 LMNB2; lamin B2
       142 PARP1; poly(ADP-ribose) polymerase 1
       10038 PARP2; poly(ADP-ribose) polymerase 2
       10039 PARP3; poly(ADP-ribose) polymerase family member 3
       143 PARP4; poly(ADP-ribose) polymerase family member 4
       1676 DFFA; DNA fragmentation factor subunit alpha
       1677 DFFB; DNA fragmentation factor subunit beta
       2021 ENDOG; endonuclease G
       9131 AIFM1; apoptosis inducing factor mitochondria associated 1
       2081 ERN1; endoplasmic reticulum to nucleus signaling 1
       7186 TRAF2; TNF receptor associated factor 2
       3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       823 CAPN1; calpain 1
       824 CAPN2; calpain 2
       100506742 CASP12; caspase 12 (gene/pseudogene)
       9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
       1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
       468 ATF4; activating transcription factor 4
       1649 DDIT3; DNA damage inducible transcript 3
       1508 CTSB; cathepsin B
       1075 CTSC; cathepsin C
       1509 CTSD; cathepsin D
       8722 CTSF; cathepsin F
       1512 CTSH; cathepsin H
       1513 CTSK; cathepsin K
       1514 CTSL; cathepsin L
       1519 CTSO; cathepsin O
       1520 CTSS; cathepsin S
       1515 CTSV; cathepsin V
       1521 CTSW; cathepsin W
       1522 CTSZ; cathepsin Z
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       332 BIRC5; baculoviral IAP repeat containing 5
       10018 BCL2L11; BCL2 like 11
       598 BCL2L1; BCL2 like 1
       596 BCL2; BCL2 apoptosis regulator
       1616 DAXX; death domain associated protein
       8737 RIPK1; receptor interacting serine/threonine kinase 1
       153090 DAB2IP; DAB2 interacting protein
       4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       572 BAD; BCL2 associated agonist of cell death
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       7157 TP53; tumor protein p53
       8739 HRK; harakiri, BCL2 interacting protein
       9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       5783 PTPN13; protein tyrosine phosphatase non-receptor type 13
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       7185 TRAF1; TNF receptor associated factor 1
       597 BCL2A1; BCL2 related protein A1
       472 ATM; ATM serine/threonine kinase
       55367 PIDD1; p53-induced death domain protein 1
       63970 TP53AIP1; tumor protein p53 regulated apoptosis inducing protein 1
       27113 BBC3; BCL2 binding component 3
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       835 CASP2; caspase 2
       4803 NGF; nerve growth factor
       4914 NTRK1; neurotrophic receptor tyrosine kinase 1
       3562 IL3; interleukin 3
       3563 IL3RA; interleukin 3 receptor subunit alpha
       1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04724 CFLAR; CASP8 and FADD-like apoptosis regulator
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10522 DIABLO; diablo
K16943 SEPT4; septin 4
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K06114 SPTAN; spectrin alpha, non-erythrocytic (fodrin)
K12641 LMNA; lamin A/C
K07611 LMNB; lamin B
K07611 LMNB; lamin B
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K02310 DFFA; DNA fragmentation factor, 45 kD, alpha subunit
K02311 DFFB; DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]
K01173 ENDOG; endonuclease G, mitochondrial
K04727 AIFM1; apoptosis-inducing factor 1 [EC:1.-.-.-]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3; DNA damage-inducible transcript 3
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01275 CTSC; cathepsin C [EC:3.4.14.1]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K01373 CTSF; cathepsin F [EC:3.4.22.41]
K01366 CTSH; cathepsin H [EC:3.4.22.16]
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01374 CTSO; cathepsin O [EC:3.4.22.42]
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K01375 CTSL2; cathepsin V [EC:3.4.22.43]
K08569 CTSW; cathepsin W [EC:3.4.22.-]
K08568 CTSZ; cathepsin X [EC:3.4.18.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16341 BCL2L11; Bcl-2-like protein 11
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K02308 DAXX; death-associated protein 6
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K19901 DAB2IP; disabled homolog 2-interacting protein
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04451 TP53; tumor protein p53
K02512 HRK; activator of apoptosis harakiri
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02374 PTPN13; tyrosine-protein phosphatase non-receptor type 13
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K03172 TRAF1; TNF receptor-associated factor 1
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K13773 TP53AIP1; p53-regulated apoptosis-inducing protein 1
K10132 BBC3; Bcl-2-binding component 3
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K02186 CASP2; caspase 2 [EC:3.4.22.55]
K02582 NGFB; nerve growth factor, beta
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04736 IL3; interleukin 3
K04737 IL3RA; interleukin 3 receptor alpha
K04738 CSF2RB; cytokine receptor common subunit beta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species [PATH:hsa04215]
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       840 CASP7; caspase 7
       836 CASP3; caspase 3
       637 BID; BH3 interacting domain death agonist
       10018 BCL2L11; BCL2 like 11
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       27113 BBC3; BCL2 binding component 3
       596 BCL2; BCL2 apoptosis regulator
       598 BCL2L1; BCL2 like 1
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
       56616 DIABLO; diablo IAP-binding mitochondrial protein
       27429 HTRA2; HtrA serine peptidase 2
       5414 SEPTIN4; septin 4
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       332 BIRC5; baculoviral IAP repeat containing 5
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       666 BOK; BCL2 family apoptosis regulator BOK
       79444 BIRC7; baculoviral IAP repeat containing 7
       4804 NGFR; nerve growth factor receptor
       8678 BECN1; beclin 1
       441925 BECN2; beclin 2
       57448 BIRC6; baculoviral IAP repeat containing 6
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16341 BCL2L11; Bcl-2-like protein 11
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K10522 DIABLO; diablo
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
K16943 SEPT4; septin 4
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02561 BOK; Bcl-2-related ovarian killer protein
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K08334 BECN; beclin
K08334 BECN; beclin
K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
     04216 Ferroptosis [PATH:hsa04216]
     04217 Necroptosis [PATH:hsa04217]
     04115 p53 signaling pathway [PATH:hsa04115]
       472 ATM; ATM serine/threonine kinase
       11200 CHEK2; checkpoint kinase 2
       545 ATR; ATR serine/threonine kinase
       1111 CHEK1; checkpoint kinase 1
       92344 GORAB; golgin, RAB6 interacting
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       4193 MDM2; MDM2 proto-oncogene
       4194 MDM4; MDM4 regulator of p53
       7157 TP53; tumor protein p53
       10848 PPP1R13L; protein phosphatase 1 regulatory subunit 13 like
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       595 CCND1; cyclin D1
       894 CCND2; cyclin D2
       896 CCND3; cyclin D3
       1019 CDK4; cyclin dependent kinase 4
       1021 CDK6; cyclin dependent kinase 6
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       1017 CDK2; cyclin dependent kinase 2
       2810 SFN; stratifin
       56475 RPRM; reprimo, TP53 dependent G2 arrest mediator homolog
       891 CCNB1; cyclin B1
       9133 CCNB2; cyclin B2
       983 CDK1; cyclin dependent kinase 1
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       51512 GTSE1; G2 and S-phase expressed 1
       25946 ZNF385A; zinc finger protein 385A
       355 FAS; Fas cell surface death receptor
       55367 PIDD1; p53-induced death domain protein 1
       8797 TNFRSF10A; TNF receptor superfamily member 10a
       8795 TNFRSF10B; TNF receptor superfamily member 10b
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       581 BAX; BCL2 associated X, apoptosis regulator
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       27113 BBC3; BCL2 binding component 3
       63970 TP53AIP1; tumor protein p53 regulated apoptosis inducing protein 1
       10572 SIVA1; SIVA1 apoptosis inducing factor
       598 BCL2L1; BCL2 like 1
       596 BCL2; BCL2 apoptosis regulator
       9540 TP53I3; tumor protein p53 inducible protein 3
       9538 EI24; EI24 autophagy associated transmembrane protein
       51246 SHISA5; shisa family member 5
       64065 PERP; p53 apoptosis effector related to PMP22
       64393 ZMAT3; zinc finger matrin-type 3
       6477 SIAH1; siah E3 ubiquitin protein ligase 1
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
       836 CASP3; caspase 3
       84883 AIFM2; apoptosis inducing factor mitochondria associated 2
       3486 IGFBP3; insulin like growth factor binding protein 3
       3479 IGF1; insulin like growth factor 1
       5054 SERPINE1; serpin family E member 1
       575 ADGRB1; adhesion G protein-coupled receptor B1
       3732 CD82; CD82 molecule
       7057 THBS1; thrombospondin 1
       5268 SERPINB5; serpin family B member 5
       1643 DDB2; damage specific DNA binding protein 2
       50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       6241 RRM2; ribonucleotide reductase regulatory subunit M2
       27244 SESN1; sestrin 1
       143686 SESN3; sestrin 3
       83667 SESN2; sestrin 2
       5728 PTEN; phosphatase and tensin homolog
       7249 TSC2; TSC complex subunit 2
       55240 STEAP3; STEAP3 metalloreductase
       64326 COP1; COP1 E3 ubiquitin ligase
       25898 RCHY1; ring finger and CHY zinc finger domain containing 1
       900 CCNG1; cyclin G1
       901 CCNG2; cyclin G2
       8493 PPM1D; protein phosphatase, Mg2+/Mn2+ dependent 1D
       7161 TP73; tumor protein p73
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04451 TP53; tumor protein p53
K27356 PPP1R13L; RelA-associated inhibitor
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K26543 ZNF385A; zinc finger protein 385A
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K13773 TP53AIP1; p53-regulated apoptosis-inducing protein 1
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K04596 ADGRB1; adhesion G protein-coupled receptor B1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
     04218 Cellular senescence [PATH:hsa04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:hsa05200]
       1630 DCC; DCC netrin 1 receptor
       836 CASP3; caspase 3
       842 CASP9; caspase 9
       26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       999 CDH1; cadherin 1
       1499 CTNNB1; catenin beta 1
       29119 CTNNA3; catenin alpha 3
       1495 CTNNA1; catenin alpha 1
       1496 CTNNA2; catenin alpha 2
       8312 AXIN1; axin 1
       8313 AXIN2; axin 2
       324 APC; APC regulator of WNT signaling pathway
       10297 APC2; APC regulator of WNT signaling pathway 2
       2932 GSK3B; glycogen synthase kinase 3 beta
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       332 BIRC5; baculoviral IAP repeat containing 5
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       595 CCND1; cyclin D1
       7471 WNT1; Wnt family member 1
       7472 WNT2; Wnt family member 2
       7482 WNT2B; Wnt family member 2B
       7473 WNT3; Wnt family member 3
       89780 WNT3A; Wnt family member 3A
       54361 WNT4; Wnt family member 4
       7474 WNT5A; Wnt family member 5A
       81029 WNT5B; Wnt family member 5B
       7475 WNT6; Wnt family member 6
       7476 WNT7A; Wnt family member 7A
       7477 WNT7B; Wnt family member 7B
       7478 WNT8A; Wnt family member 8A
       7479 WNT8B; Wnt family member 8B
       7483 WNT9A; Wnt family member 9A
       7484 WNT9B; Wnt family member 9B
       7480 WNT10B; Wnt family member 10B
       80326 WNT10A; Wnt family member 10A
       7481 WNT11; Wnt family member 11
       51384 WNT16; Wnt family member 16
       8321 FZD1; frizzled class receptor 1
       8324 FZD7; frizzled class receptor 7
       2535 FZD2; frizzled class receptor 2
       7976 FZD3; frizzled class receptor 3
       8322 FZD4; frizzled class receptor 4
       7855 FZD5; frizzled class receptor 5
       8325 FZD8; frizzled class receptor 8
       8323 FZD6; frizzled class receptor 6
       11211 FZD10; frizzled class receptor 10
       8326 FZD9; frizzled class receptor 9
       4041 LRP5; LDL receptor related protein 5
       4040 LRP6; LDL receptor related protein 6
       1857 DVL3; dishevelled segment polarity protein 3
       1856 DVL2; dishevelled segment polarity protein 2
       1855 DVL1; dishevelled segment polarity protein 1
       10023 FRAT1; FRAT regulator of WNT signaling pathway 1
       23401 FRAT2; FRAT regulator of WNT signaling pathway 2
       2147 F2; coagulation factor II, thrombin
       183 AGT; angiotensinogen
       2149 F2R; coagulation factor II thrombin receptor
       9002 F2RL3; F2R like thrombin or trypsin receptor 3
       1902 LPAR1; lysophosphatidic acid receptor 1
       9170 LPAR2; lysophosphatidic acid receptor 2
       23566 LPAR3; lysophosphatidic acid receptor 3
       2846 LPAR4; lysophosphatidic acid receptor 4
       57121 LPAR5; lysophosphatidic acid receptor 5
       10161 LPAR6; lysophosphatidic acid receptor 6
       185 AGTR1; angiotensin II receptor type 1
       2768 GNA12; G protein subunit alpha 12
       10672 GNA13; G protein subunit alpha 13
       23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
       9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
       9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
       57449 PLEKHG5; pleckstrin homology and RhoGEF domain containing G5
       387 RHOA; ras homolog family member A
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       6387 CXCL12; C-X-C motif chemokine ligand 12
       7852 CXCR4; C-X-C motif chemokine receptor 4
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       5731 PTGER1; prostaglandin E receptor 1
       5732 PTGER2; prostaglandin E receptor 2
       5733 PTGER3; prostaglandin E receptor 3
       5734 PTGER4; prostaglandin E receptor 4
       2778 GNAS; GNAS complex locus
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       2782 GNB1; G protein subunit beta 1
       2783 GNB2; G protein subunit beta 2
       2784 GNB3; G protein subunit beta 3
       59345 GNB4; G protein subunit beta 4
       10681 GNB5; G protein subunit beta 5
       54331 GNG2; G protein subunit gamma 2
       2785 GNG3; G protein subunit gamma 3
       2786 GNG4; G protein subunit gamma 4
       2787 GNG5; G protein subunit gamma 5
       2788 GNG7; G protein subunit gamma 7
       94235 GNG8; G protein subunit gamma 8
       2790 GNG10; G protein subunit gamma 10
       2791 GNG11; G protein subunit gamma 11
       55970 GNG12; G protein subunit gamma 12
       51764 GNG13; G protein subunit gamma 13
       2792 GNGT1; G protein subunit gamma transducin 1
       2793 GNGT2; G protein subunit gamma transducin 2
       1284 COL4A2; collagen type IV alpha 2 chain
       1286 COL4A4; collagen type IV alpha 4 chain
       1288 COL4A6; collagen type IV alpha 6 chain
       1282 COL4A1; collagen type IV alpha 1 chain
       1287 COL4A5; collagen type IV alpha 5 chain
       1285 COL4A3; collagen type IV alpha 3 chain
       284217 LAMA1; laminin subunit alpha 1
       3908 LAMA2; laminin subunit alpha 2
       3909 LAMA3; laminin subunit alpha 3
       3911 LAMA5; laminin subunit alpha 5
       3910 LAMA4; laminin subunit alpha 4
       3912 LAMB1; laminin subunit beta 1
       3913 LAMB2; laminin subunit beta 2
       3914 LAMB3; laminin subunit beta 3
       22798 LAMB4; laminin subunit beta 4
       3915 LAMC1; laminin subunit gamma 1
       3918 LAMC2; laminin subunit gamma 2
       10319 LAMC3; laminin subunit gamma 3
       2335 FN1; fibronectin 1
       3673 ITGA2; integrin subunit alpha 2
       3674 ITGA2B; integrin subunit alpha 2b
       3675 ITGA3; integrin subunit alpha 3
       3655 ITGA6; integrin subunit alpha 6
       3685 ITGAV; integrin subunit alpha V
       3688 ITGB1; integrin subunit beta 1
       5747 PTK2; protein tyrosine kinase 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5728 PTEN; phosphatase and tensin homolog
       4824 NKX3-1; NK3 homeobox 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       4791 NFKB2; nuclear factor kappa B subunit 2
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       5743 PTGS2; prostaglandin-endoperoxide synthase 2
       4843 NOS2; nitric oxide synthase 2
       596 BCL2; BCL2 apoptosis regulator
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       79444 BIRC7; baculoviral IAP repeat containing 7
       598 BCL2L1; BCL2 like 1
       7185 TRAF1; TNF receptor associated factor 1
       7186 TRAF2; TNF receptor associated factor 2
       7187 TRAF3; TNF receptor associated factor 3
       9618 TRAF4; TNF receptor associated factor 4
       7188 TRAF5; TNF receptor associated factor 5
       7189 TRAF6; TNF receptor associated factor 6
       2475 MTOR; mechanistic target of rapamycin kinase
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       572 BAD; BCL2 associated agonist of cell death
       2308 FOXO1; forkhead box O1
       4193 MDM2; MDM2 proto-oncogene
       7157 TP53; tumor protein p53
       1027 CDKN1B; cyclin dependent kinase inhibitor 1B
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       613 BCR; BCR activator of RhoGEF and GTPase
       25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       867 CBL; Cbl proto-oncogene
       6776 STAT5A; signal transducer and activator of transcription 5A
       6777 STAT5B; signal transducer and activator of transcription 5B
       5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
       11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
       3827 KNG1; kininogen 1
       1906 EDN1; endothelin 1
       623 BDKRB1; bradykinin receptor B1
       624 BDKRB2; bradykinin receptor B2
       1909 EDNRA; endothelin receptor type A
       1910 EDNRB; endothelin receptor type B
       2776 GNAQ; G protein subunit alpha q
       2767 GNA11; G protein subunit alpha 11
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       3558 IL2; interleukin 2
       3562 IL3; interleukin 3
       3565 IL4; interleukin 4
       3567 IL5; interleukin 5
       3569 IL6; interleukin 6
       3574 IL7; interleukin 7
       3592 IL12A; interleukin 12A
       3593 IL12B; interleukin 12B
       3596 IL13; interleukin 13
       3600 IL15; interleukin 15
       51561 IL23A; interleukin 23 subunit alpha
       2056 EPO; erythropoietin
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3458 IFNG; interferon gamma
       3559 IL2RA; interleukin 2 receptor subunit alpha
       3560 IL2RB; interleukin 2 receptor subunit beta
       3561 IL2RG; interleukin 2 receptor subunit gamma
       3563 IL3RA; interleukin 3 receptor subunit alpha
       3566 IL4R; interleukin 4 receptor
       1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
       3568 IL5RA; interleukin 5 receptor subunit alpha
       3570 IL6R; interleukin 6 receptor
       3572 IL6ST; interleukin 6 cytokine family signal transducer
       3575 IL7R; interleukin 7 receptor
       3594 IL12RB1; interleukin 12 receptor subunit beta 1
       3595 IL12RB2; interleukin 12 receptor subunit beta 2
       3597 IL13RA1; interleukin 13 receptor subunit alpha 1
       3601 IL15RA; interleukin 15 receptor subunit alpha
       149233 IL23R; interleukin 23 receptor
       2057 EPOR; erythropoietin receptor
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       3459 IFNGR1; interferon gamma receptor 1
       3460 IFNGR2; interferon gamma receptor 2
       27436 EML4; EMAP like 4
       238 ALK; ALK receptor tyrosine kinase
       10125 RASGRP1; RAS guanyl releasing protein 1
       10235 RASGRP2; RAS guanyl releasing protein 2
       25780 RASGRP3; RAS guanyl releasing protein 3
       115727 RASGRP4; RAS guanyl releasing protein 4
       3716 JAK1; Janus kinase 1
       3717 JAK2; Janus kinase 2
       3718 JAK3; Janus kinase 3
       6774 STAT3; signal transducer and activator of transcription 3
       6772 STAT1; signal transducer and activator of transcription 1
       6773 STAT2; signal transducer and activator of transcription 2
       6775 STAT4; signal transducer and activator of transcription 4
       6778 STAT6; signal transducer and activator of transcription 6
       7422 VEGFA; vascular endothelial growth factor A
       7423 VEGFB; vascular endothelial growth factor B
       5228 PGF; placental growth factor
       7424 VEGFC; vascular endothelial growth factor C
       2277 VEGFD; vascular endothelial growth factor D
       7039 TGFA; transforming growth factor alpha
       1950 EGF; epidermal growth factor
       1956 EGFR; epidermal growth factor receptor
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       5154 PDGFA; platelet derived growth factor subunit A
       5155 PDGFB; platelet derived growth factor subunit B
       5156 PDGFRA; platelet derived growth factor receptor alpha
       5159 PDGFRB; platelet derived growth factor receptor beta
       3479 IGF1; insulin like growth factor 1
       3481 IGF2; insulin like growth factor 2
       3480 IGF1R; insulin like growth factor 1 receptor
       4254 KITLG; KIT ligand
       3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
       2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
       2322 FLT3; fms related receptor tyrosine kinase 3
       3082 HGF; hepatocyte growth factor
       4233 MET; MET proto-oncogene, receptor tyrosine kinase
       2246 FGF1; fibroblast growth factor 1
       2247 FGF2; fibroblast growth factor 2
       2248 FGF3; fibroblast growth factor 3
       2249 FGF4; fibroblast growth factor 4
       8822 FGF17; fibroblast growth factor 17
       2251 FGF6; fibroblast growth factor 6
       2252 FGF7; fibroblast growth factor 7
       2253 FGF8; fibroblast growth factor 8
       2254 FGF9; fibroblast growth factor 9
       2255 FGF10; fibroblast growth factor 10
       8823 FGF16; fibroblast growth factor 16
       2250 FGF5; fibroblast growth factor 5
       8817 FGF18; fibroblast growth factor 18
       26281 FGF20; fibroblast growth factor 20
       27006 FGF22; fibroblast growth factor 22
       9965 FGF19; fibroblast growth factor 19
       26291 FGF21; fibroblast growth factor 21
       8074 FGF23; fibroblast growth factor 23
       2260 FGFR1; fibroblast growth factor receptor 1
       2263 FGFR2; fibroblast growth factor receptor 2
       2261 FGFR3; fibroblast growth factor receptor 3
       2264 FGFR4; fibroblast growth factor receptor 4
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       2113 ETS1; ETS proto-oncogene 1, transcription factor
       4312 MMP1; matrix metallopeptidase 1
       4313 MMP2; matrix metallopeptidase 2
       4318 MMP9; matrix metallopeptidase 9
       3576 CXCL8; C-X-C motif chemokine ligand 8
       1019 CDK4; cyclin dependent kinase 4
       9252 RPS6KA5; ribosomal protein S6 kinase A5
       5979 RET; ret proto-oncogene
       8030 CCDC6; coiled-coil domain containing 6
       8031 NCOA4; nuclear receptor coactivator 4
       4914 NTRK1; neurotrophic receptor tyrosine kinase 1
       7170 TPM3; tropomyosin 3
       7175 TPR; translocated promoter region, nuclear basket protein
       10342 TFG; trafficking from ER to golgi regulator
       11186 RASSF1; Ras association domain family member 1
       83593 RASSF5; Ras association domain family member 5
       6789 STK4; serine/threonine kinase 4
       1612 DAPK1; death associated protein kinase 1
       1613 DAPK3; death associated protein kinase 3
       23604 DAPK2; death associated protein kinase 2
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       2002 ELK1; ETS transcription factor ELK1
       810 CALML3; calmodulin like 3
       805 CALM2; calmodulin 2
       808 CALM3; calmodulin 3
       801 CALM1; calmodulin 1
       163688 CALML6; calmodulin like 6
       51806 CALML5; calmodulin like 5
       91860 CALML4; calmodulin like 4
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       5900 RALGDS; ral guanine nucleotide dissociation stimulator
       5898 RALA; RAS like proto-oncogene A
       5899 RALB; RAS like proto-oncogene B
       10928 RALBP1; ralA binding protein 1
       998 CDC42; cell division cycle 42
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       5337 PLD1; phospholipase D1
       5338 PLD2; phospholipase D2
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       7849 PAX8; paired box 8
       5468 PPARG; peroxisome proliferator activated receptor gamma
       6256 RXRA; retinoid X receptor alpha
       6257 RXRB; retinoid X receptor beta
       6258 RXRG; retinoid X receptor gamma
       5915 RARB; retinoic acid receptor beta
       2099 ESR1; estrogen receptor 1
       2100 ESR2; estrogen receptor 2
       8648 NCOA1; nuclear receptor coactivator 1
       8202 NCOA3; nuclear receptor coactivator 3
       6667 SP1; Sp1 transcription factor
       5467 PPARD; peroxisome proliferator activated receptor delta
       3728 JUP; junction plakoglobin
       7704 ZBTB16; zinc finger and BTB domain containing 16
       5914 RARA; retinoic acid receptor alpha
       890 CCNA2; cyclin A2
       8900 CCNA1; cyclin A1
       5371 PML; PML nuclear body scaffold
       861 RUNX1; RUNX family transcription factor 1
       862 RUNX1T1; RUNX1 partner transcriptional co-repressor 1
       6688 SPI1; Spi-1 proto-oncogene
       1050 CEBPA; CCAAT enhancer binding protein alpha
       1438 CSF2RA; colony stimulating factor 2 receptor subunit alpha
       1441 CSF3R; colony stimulating factor 3 receptor
       1436 CSF1R; colony stimulating factor 1 receptor
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       4149 MAX; MYC associated factor X
       7709 ZBTB17; zinc finger and BTB domain containing 17
       1030 CDKN2B; cyclin dependent kinase inhibitor 2B
       1021 CDK6; cyclin dependent kinase 6
       894 CCND2; cyclin D2
       896 CCND3; cyclin D3
       1163 CKS1B; CDC28 protein kinase regulatory subunit 1B
       1164 CKS2; CDC28 protein kinase regulatory subunit 2
       6500 SKP1; S-phase kinase associated protein 1
       8454 CUL1; cullin 1
       9978 RBX1; ring-box 1
       6502 SKP2; S-phase kinase associated protein 2
       1017 CDK2; cyclin dependent kinase 2
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       5925 RB1; RB transcriptional corepressor 1
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       1643 DDB2; damage specific DNA binding protein 2
       51426 POLK; DNA polymerase kappa
       7015 TERT; telomerase reverse transcriptase
       7012 TERC; telomerase RNA component
       4286 MITF; melanocyte inducing transcription factor
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       7046 TGFBR1; transforming growth factor beta receptor 1
       7048 TGFBR2; transforming growth factor beta receptor 2
       4087 SMAD2; SMAD family member 2
       4088 SMAD3; SMAD family member 3
       4089 SMAD4; SMAD family member 4
       2122 MECOM; MDS1 and EVI1 complex locus
       1487 CTBP1; C-terminal binding protein 1
       1488 CTBP2; C-terminal binding protein 2
       3065 HDAC1; histone deacetylase 1
       3066 HDAC2; histone deacetylase 2
       4292 MLH1; mutL homolog 1
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       675 BRCA2; BRCA2 DNA repair associated
       5888 RAD51; RAD51 recombinase
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       27113 BBC3; BCL2 binding component 3
       10018 BCL2L11; BCL2 like 11
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       840 CASP7; caspase 7
       9817 KEAP1; kelch like ECH associated protein 1
       4780 NFE2L2; NFE2 like bZIP transcription factor 2
       3162 HMOX1; heme oxygenase 1
       1728 NQO1; NAD(P)H quinone dehydrogenase 1
       221357 GSTA5; glutathione S-transferase alpha 5
       2939 GSTA2; glutathione S-transferase alpha 2
       2941 GSTA4; glutathione S-transferase alpha 4
       119391 GSTO2; glutathione S-transferase omega 2
       2948 GSTM4; glutathione S-transferase mu 4
       2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
       2952 GSTT1; glutathione S-transferase theta 1
       2947 GSTM3; glutathione S-transferase mu 3
       4257 MGST1; microsomal glutathione S-transferase 1
       4259 MGST3; microsomal glutathione S-transferase 3
       2944 GSTM1; glutathione S-transferase mu 1
       2949 GSTM5; glutathione S-transferase mu 5
       4258 MGST2; microsomal glutathione S-transferase 2
       2938 GSTA1; glutathione S-transferase alpha 1
       2946 GSTM2; glutathione S-transferase mu 2
       2940 GSTA3; glutathione S-transferase alpha 3
       9446 GSTO1; glutathione S-transferase omega 1
       653689 GSTT2B; glutathione S-transferase theta 2B
       2950 GSTP1; glutathione S-transferase pi 1
       7296 TXNRD1; thioredoxin reductase 1
       114112 TXNRD3; thioredoxin reductase 3
       10587 TXNRD2; thioredoxin reductase 2
       7428 VHL; von Hippel-Lindau tumor suppressor
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       8453 CUL2; cullin 2
       54583 EGLN1; egl-9 family hypoxia inducible factor 1
       112399 EGLN3; egl-9 family hypoxia inducible factor 3
       112398 EGLN2; egl-9 family hypoxia inducible factor 2
       2271 FH; fumarate hydratase
       3091 HIF1A; hypoxia inducible factor 1 subunit alpha
       2034 EPAS1; endothelial PAS domain protein 1
       405 ARNT; aryl hydrocarbon receptor nuclear translocator
       9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       6513 SLC2A1; solute carrier family 2 member 1
       182 JAG1; jagged canonical Notch ligand 1
       3714 JAG2; jagged canonical Notch ligand 2
       10683 DLL3; delta like canonical Notch ligand 3
       28514 DLL1; delta like canonical Notch ligand 1
       54567 DLL4; delta like canonical Notch ligand 4
       4851 NOTCH1; notch receptor 1
       4853 NOTCH2; notch receptor 2
       4854 NOTCH3; notch receptor 3
       4855 NOTCH4; notch receptor 4
       3280 HES1; hes family bHLH transcription factor 1
       388585 HES5; hes family bHLH transcription factor 5
       26508 HEYL; hes related family bHLH transcription factor with YRPW motif like
       23462 HEY1; hes related family bHLH transcription factor with YRPW motif 1
       23493 HEY2; hes related family bHLH transcription factor with YRPW motif 2
       2324 FLT4; fms related receptor tyrosine kinase 4
       6469 SHH; sonic hedgehog signaling molecule
       5727 PTCH1; patched 1
       6608 SMO; smoothened, frizzled class receptor
       374654 KIF7; kinesin family member 7
       51684 SUFU; SUFU negative regulator of hedgehog signaling
       2735 GLI1; GLI family zinc finger 1
       2736 GLI2; GLI family zinc finger 2
       2737 GLI3; GLI family zinc finger 3
       650 BMP2; bone morphogenetic protein 2
       652 BMP4; bone morphogenetic protein 4
       64399 HHIP; hedgehog interacting protein
       8643 PTCH2; patched 2
       367 AR; androgen receptor
       3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
       3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
       7184 HSP90B1; heat shock protein 90 beta family member 1
       354 KLK3; kallikrein related peptidase 3
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancer [PATH:hsa05202]
     05206 MicroRNAs in cancer [PATH:hsa05206]
     05205 Proteoglycans in cancer [PATH:hsa05205]
     05204 Chemical carcinogenesis - DNA adducts [PATH:hsa05204]
     05207 Chemical carcinogenesis - receptor activation [PATH:hsa05207]
     05208 Chemical carcinogenesis - reactive oxygen species [PATH:hsa05208]
     05203 Viral carcinogenesis [PATH:hsa05203]
     05230 Central carbon metabolism in cancer [PATH:hsa05230]
     05231 Choline metabolism in cancer [PATH:hsa05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:hsa05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:hsa05210]
       2932 GSK3B; glycogen synthase kinase 3 beta
       8312 AXIN1; axin 1
       8313 AXIN2; axin 2
       1499 CTNNB1; catenin beta 1
       324 APC; APC regulator of WNT signaling pathway
       10297 APC2; APC regulator of WNT signaling pathway 2
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       332 BIRC5; baculoviral IAP repeat containing 5
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       595 CCND1; cyclin D1
       3845 KRAS; KRAS proto-oncogene, GTPase
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       572 BAD; BCL2 associated agonist of cell death
       842 CASP9; caspase 9
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       5900 RALGDS; ral guanine nucleotide dissociation stimulator
       5898 RALA; RAS like proto-oncogene A
       5899 RALB; RAS like proto-oncogene B
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       387 RHOA; ras homolog family member A
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       1630 DCC; DCC netrin 1 receptor
       836 CASP3; caspase 3
       26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       7046 TGFBR1; transforming growth factor beta receptor 1
       7048 TGFBR2; transforming growth factor beta receptor 2
       4087 SMAD2; SMAD family member 2
       4088 SMAD3; SMAD family member 3
       4089 SMAD4; SMAD family member 4
       4292 MLH1; mutL homolog 1
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       581 BAX; BCL2 associated X, apoptosis regulator
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       10018 BCL2L11; BCL2 like 11
       27113 BBC3; BCL2 binding component 3
       596 BCL2; BCL2 apoptosis regulator
       54205 CYCS; cytochrome c, somatic
       7157 TP53; tumor protein p53
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       578 BAK1; BCL2 antagonist/killer 1
       1643 DDB2; damage specific DNA binding protein 2
       51426 POLK; DNA polymerase kappa
       1950 EGF; epidermal growth factor
       7039 TGFA; transforming growth factor alpha
       2069 EREG; epiregulin
       374 AREG; amphiregulin
       1956 EGFR; epidermal growth factor receptor
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       2475 MTOR; mechanistic target of rapamycin kinase
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
     05212 Pancreatic cancer [PATH:hsa05212]
     05225 Hepatocellular carcinoma [PATH:hsa05225]
     05226 Gastric cancer [PATH:hsa05226]
     05214 Glioma [PATH:hsa05214]
     05216 Thyroid cancer [PATH:hsa05216]
     05221 Acute myeloid leukemia [PATH:hsa05221]
     05220 Chronic myeloid leukemia [PATH:hsa05220]
     05217 Basal cell carcinoma [PATH:hsa05217]
     05218 Melanoma [PATH:hsa05218]
     05211 Renal cell carcinoma [PATH:hsa05211]
     05219 Bladder cancer [PATH:hsa05219]
     05215 Prostate cancer [PATH:hsa05215]
     05213 Endometrial cancer [PATH:hsa05213]
     05224 Breast cancer [PATH:hsa05224]
     05222 Small cell lung cancer [PATH:hsa05222]
     05223 Non-small cell lung cancer [PATH:hsa05223]
 
   09172 Infectious disease: viral
     05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
     05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
     05161 Hepatitis B [PATH:hsa05161]
     05160 Hepatitis C [PATH:hsa05160]
     05171 Coronavirus disease - COVID-19 [PATH:hsa05171]
     05164 Influenza A [PATH:hsa05164]
     05162 Measles [PATH:hsa05162]
       4179 CD46; CD46 molecule
       4478 MSN; moesin
       6504 SLAMF1; signaling lymphocytic activation molecule family member 1
       10332 CLEC4M; C-type lectin domain family 4 member M
       30835 CD209; CD209 molecule
       23586 RIGI; RNA sensor RIG-I
       64135 IFIH1; interferon induced with helicase C domain 1
       57506 MAVS; mitochondrial antiviral signaling protein
       7187 TRAF3; TNF receptor associated factor 3
       9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
       29110 TBK1; TANK binding kinase 1
       3661 IRF3; interferon regulatory factor 3
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4793 NFKBIB; NFKB inhibitor beta
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       51284 TLR7; toll like receptor 7
       54106 TLR9; toll like receptor 9
       4615 MYD88; MYD88 innate immune signal transduction adaptor
       3654 IRAK1; interleukin 1 receptor associated kinase 1
       51135 IRAK4; interleukin 1 receptor associated kinase 4
       3665 IRF7; interferon regulatory factor 7
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3456 IFNB1; interferon beta 1
       7097 TLR2; toll like receptor 2
       7099 TLR4; toll like receptor 4
       7189 TRAF6; TNF receptor associated factor 6
       1457 CSNK2A1; casein kinase 2 alpha 1
       1459 CSNK2A2; casein kinase 2 alpha 2
       283106 CSNK2A3; casein kinase 2 alpha 3
       1460 CSNK2B; casein kinase 2 beta
       7128 TNFAIP3; TNF alpha induced protein 3
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       3552 IL1A; interleukin 1 alpha
       3553 IL1B; interleukin 1 beta
       3569 IL6; interleukin 6
       3592 IL12A; interleukin 12A
       3593 IL12B; interleukin 12B
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       10399 RACK1; receptor for activated C kinase 1
       3716 JAK1; Janus kinase 1
       7297 TYK2; tyrosine kinase 2
       6772 STAT1; signal transducer and activator of transcription 1
       6773 STAT2; signal transducer and activator of transcription 2
       10379 IRF9; interferon regulatory factor 9
       4938 OAS1; 2'-5'-oligoadenylate synthetase 1
       4939 OAS2; 2'-5'-oligoadenylate synthetase 2
       4940 OAS3; 2'-5'-oligoadenylate synthetase 3
       103 ADAR; adenosine deaminase RNA specific
       4599 MX1; MX dynamin like GTPase 1
       4600 MX2; MX dynamin like GTPase 2
       27102 EIF2AK1; eukaryotic translation initiation factor 2 alpha kinase 1
       5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
       9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
       440275 EIF2AK4; eukaryotic translation initiation factor 2 alpha kinase 4
       9367 RAB9A; RAB9A, member RAS oncogene family
       51209 RAB9B; RAB9B, member RAS oncogene family
       3312 HSPA8; heat shock protein family A (Hsp70) member 8
       3303 HSPA1A; heat shock protein family A (Hsp70) member 1A
       3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like
       3304 HSPA1B; heat shock protein family A (Hsp70) member 1B
       3310 HSPA6; heat shock protein family A (Hsp70) member 6
       8667 EIF3H; eukaryotic translation initiation factor 3 subunit H
       1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
       25898 RCHY1; ring finger and CHY zinc finger domain containing 1
       7157 TP53; tumor protein p53
       7161 TP73; tumor protein p73
       27113 BBC3; BCL2 binding component 3
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       8717 TRADD; TNFRSF1A associated via death domain
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       596 BCL2; BCL2 apoptosis regulator
       598 BCL2L1; BCL2 like 1
       572 BAD; BCL2 associated agonist of cell death
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
       836 CASP3; caspase 3
       1027 CDKN1B; cyclin dependent kinase inhibitor 1B
       595 CCND1; cyclin D1
       894 CCND2; cyclin D2
       896 CCND3; cyclin D3
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       1019 CDK4; cyclin dependent kinase 4
       1021 CDK6; cyclin dependent kinase 6
       1017 CDK2; cyclin dependent kinase 2
       915 CD3D; CD3 delta subunit of T-cell receptor complex
       916 CD3E; CD3 epsilon subunit of T-cell receptor complex
       917 CD3G; CD3 gamma subunit of T-cell receptor complex
       940 CD28; CD28 molecule
       3558 IL2; interleukin 2
       3559 IL2RA; interleukin 2 receptor subunit alpha
       3560 IL2RB; interleukin 2 receptor subunit beta
       3561 IL2RG; interleukin 2 receptor subunit gamma
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       868 CBLB; Cbl proto-oncogene B
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       2932 GSK3B; glycogen synthase kinase 3 beta
       3718 JAK3; Janus kinase 3
       6774 STAT3; signal transducer and activator of transcription 3
       6776 STAT5A; signal transducer and activator of transcription 5A
       6777 STAT5B; signal transducer and activator of transcription 5B
       2213 FCGR2B; Fc gamma receptor IIb
K04007 CD46; membrane cofactor protein
K05763 MSN; moesin
K06536 SLAMF1; signaling lymphocytic activation molecule family member 1
K06563 CLEC4L_M; C-type lectin domain family 4 member L/M
K06563 CLEC4L_M; C-type lectin domain family 4 member L/M
K12646 DDX58; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12648 MAVS; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05404 TLR7; toll-like receptor 7
K10161 TLR9; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2; TAK1-binding protein 2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9; interferon regulatory factor 9
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K12968 ADAR; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K14754 MX; interferon-induced GTP-binding protein Mx
K14754 MX; interferon-induced GTP-binding protein Mx
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K07899 RAB9A; Ras-related protein Rab-9A
K07900 RAB9B; Ras-related protein Rab-9B
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03247 EIF3H; translation initiation factor 3 subunit H
K03237 EIF2S1; translation initiation factor 2 subunit 1
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K10148 TP73; tumor protein p73
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02158 BAD; Bcl-2-antagonist of cell death
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K12560 FCGR2B; low affinity immunoglobulin gamma Fc receptor II-b
     05168 Herpes simplex virus 1 infection [PATH:hsa05168]
     05163 Human cytomegalovirus infection [PATH:hsa05163]
     05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
     05169 Epstein-Barr virus infection [PATH:hsa05169]
     05165 Human papillomavirus infection [PATH:hsa05165]
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
     05010 Alzheimer disease [PATH:hsa05010]
     05012 Parkinson disease [PATH:hsa05012]
     05014 Amyotrophic lateral sclerosis [PATH:hsa05014]
     05016 Huntington disease [PATH:hsa05016]
       1211 CLTA; clathrin light chain A
       1212 CLTB; clathrin light chain B
       1213 CLTC; clathrin heavy chain
       8218 CLTCL1; clathrin heavy chain like 1
       3092 HIP1; huntingtin interacting protein 1
       161 AP2A2; adaptor related protein complex 2 subunit alpha 2
       160 AP2A1; adaptor related protein complex 2 subunit alpha 1
       163 AP2B1; adaptor related protein complex 2 subunit beta 1
       1173 AP2M1; adaptor related protein complex 2 subunit mu 1
       1175 AP2S1; adaptor related protein complex 2 subunit sigma 1
       3064 HTT; huntingtin
       1639 DCTN1; dynactin subunit 1
       10540 DCTN2; dynactin subunit 2
       11258 DCTN3; dynactin subunit 3
       51164 DCTN4; dynactin subunit 4
       84516 DCTN5; dynactin subunit 5
       10671 DCTN6; dynactin subunit 6
       10121 ACTR1A; actin related protein 1A
       10120 ACTR1B; actin related protein 1B
       55860 ACTR10; actin related protein 10
       9001 HAP1; huntingtin associated protein 1
       25981 DNAH1; dynein axonemal heavy chain 1
       55567 DNAH3; dynein axonemal heavy chain 3
       146754 DNAH2; dynein axonemal heavy chain 2
       56171 DNAH7; dynein axonemal heavy chain 7
       1767 DNAH5; dynein axonemal heavy chain 5
       1768 DNAH6; dynein axonemal heavy chain 6
       1770 DNAH9; dynein axonemal heavy chain 9
       8701 DNAH11; dynein axonemal heavy chain 11
       201625 DNAH12; dynein axonemal heavy chain 12
       127602 DNAH14; dynein axonemal heavy chain 14
       1769 DNAH8; dynein axonemal heavy chain 8
       196385 DNAH10; dynein axonemal heavy chain 10
       8632 DNAH17; dynein axonemal heavy chain 17
       7802 DNALI1; dynein axonemal light intermediate chain 1
       27019 DNAI1; dynein axonemal intermediate chain 1
       64446 DNAI2; dynein axonemal intermediate chain 2
       83544 DNAL1; dynein axonemal light chain 1
       10126 DNAL4; dynein axonemal light chain 4
       10376 TUBA1B; tubulin alpha 1b
       7277 TUBA4A; tubulin alpha 4a
       7278 TUBA3C; tubulin alpha 3c
       7846 TUBA1A; tubulin alpha 1a
       84790 TUBA1C; tubulin alpha 1c
       51807 TUBA8; tubulin alpha 8
       112714 TUBA3E; tubulin alpha 3e
       113457 TUBA3D; tubulin alpha 3d
       79861 TUBAL3; tubulin alpha like 3
       84617 TUBB6; tubulin beta 6 class V
       203068 TUBB; tubulin beta class I
       81027 TUBB1; tubulin beta 1 class VI
       7280 TUBB2A; tubulin beta 2A class IIa
       10381 TUBB3; tubulin beta 3 class III
       10382 TUBB4A; tubulin beta 4A class IVa
       347688 TUBB8; tubulin beta 8 class VIII
       347733 TUBB2B; tubulin beta 2B class IIb
       10383 TUBB4B; tubulin beta 4B class IVb
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       3798 KIF5A; kinesin family member 5A
       3799 KIF5B; kinesin family member 5B
       3800 KIF5C; kinesin family member 5C
       147700 KLC3; kinesin light chain 3
       3831 KLC1; kinesin light chain 1
       64837 KLC2; kinesin light chain 2
       89953 KLC4; kinesin light chain 4
       55081 IFT57; intraflagellar transport 57
       841 CASP8; caspase 8
       836 CASP3; caspase 3
       2915 GRM5; glutamate metabotropic receptor 5
       2776 GNAQ; G protein subunit alpha q
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       6804 STX1A; syntaxin 1A
       774 CACNA1B; calcium voltage-gated channel subunit alpha1 B
       2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
       2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
       3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       1742 DLG4; discs large MAGUK scaffold protein 4
       2890 GRIA1; glutamate ionotropic receptor AMPA type subunit 1
       2891 GRIA2; glutamate ionotropic receptor AMPA type subunit 2
       2892 GRIA3; glutamate ionotropic receptor AMPA type subunit 3
       2893 GRIA4; glutamate ionotropic receptor AMPA type subunit 4
       7052 TGM2; transglutaminase 2
       6507 SLC1A3; solute carrier family 1 member 3
       6506 SLC1A2; solute carrier family 1 member 2
       3766 KCNJ10; potassium inwardly rectifying channel subfamily J member 10
       5978 REST; RE1 silencing transcription factor
       25942 SIN3A; SIN3 transcription regulator family member A
       23186 RCOR1; REST corepressor 1
       3065 HDAC1; histone deacetylase 1
       3066 HDAC2; histone deacetylase 2
       5430 POLR2A; RNA polymerase II subunit A
       5431 POLR2B; RNA polymerase II subunit B
       5432 POLR2C; RNA polymerase II subunit C
       5433 POLR2D; RNA polymerase II subunit D
       5434 POLR2E; RNA polymerase II, I and III subunit E
       5435 POLR2F; RNA polymerase II, I and III subunit F
       5436 POLR2G; RNA polymerase II subunit G
       5437 POLR2H; RNA polymerase II, I and III subunit H
       5438 POLR2I; RNA polymerase II subunit I
       5441 POLR2L; RNA polymerase II, I and III subunit L
       5439 POLR2J; RNA polymerase II subunit J
       548644 POLR2J3; RNA polymerase II subunit J3
       246721 POLR2J2; RNA polymerase II subunit J2
       5440 POLR2K; RNA polymerase II, I and III subunit K
       627 BDNF; brain derived neurotrophic factor
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       6875 TAF4B; TATA-box binding protein associated factor 4b
       6874 TAF4; TATA-box binding protein associated factor 4
       387332 TBPL2; TATA-box binding protein like 2
       9519 TBPL1; TATA-box binding protein like 1
       6908 TBP; TATA-box binding protein
       6667 SP1; Sp1 transcription factor
       1385 CREB1; cAMP responsive element binding protein 1
       10488 CREB3; cAMP responsive element binding protein 3
       90993 CREB3L1; cAMP responsive element binding protein 3 like 1
       64764 CREB3L2; cAMP responsive element binding protein 3 like 2
       84699 CREB3L3; cAMP responsive element binding protein 3 like 3
       148327 CREB3L4; cAMP responsive element binding protein 3 like 4
       9586 CREB5; cAMP responsive element binding protein 5
       10891 PPARGC1A; PPARG coactivator 1 alpha
       5468 PPARG; peroxisome proliferator activated receptor gamma
       7019 TFAM; transcription factor A, mitochondrial
       4899 NRF1; nuclear respiratory factor 1
       6647 SOD1; superoxide dismutase 1
       6648 SOD2; superoxide dismutase 2
       257202 GPX6; glutathione peroxidase 6
       2882 GPX7; glutathione peroxidase 7
       2877 GPX2; glutathione peroxidase 2
       2878 GPX3; glutathione peroxidase 3
       2876 GPX1; glutathione peroxidase 1
       2880 GPX5; glutathione peroxidase 5
       493869 GPX8; glutathione peroxidase 8 (putative)
       7350 UCP1; uncoupling protein 1
       7157 TP53; tumor protein p53
       581 BAX; BCL2 associated X, apoptosis regulator
       27113 BBC3; BCL2 binding component 3
       4535 ND1; NADH dehydrogenase subunit 1
       4536 ND2; NADH dehydrogenase subunit 2
       4537 ND3; NADH dehydrogenase subunit 3
       4538 ND4; NADH dehydrogenase subunit 4
       4539 ND4L; NADH dehydrogenase subunit 4L
       4540 ND5; NADH dehydrogenase subunit 5
       4541 ND6; NADH dehydrogenase subunit 6
       4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1
       4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2
       4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3
       4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1
       4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2
       4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
       4697 NDUFA4; NDUFA4 mitochondrial complex associated
       56901 NDUFA4L2; NDUFA4 mitochondrial complex associated like 2
       4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5
       4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
       4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
       4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8
       4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9
       4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10
       4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
       126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11
       55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
       51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13
       4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
       4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2
       4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
       4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4
       4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5
       4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6
       4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7
       4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
       4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
       4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10
       54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
       4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1
       4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2
       4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3
       4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
       4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5
       4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6
       374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7
       4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8
       4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
       4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
       100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
       6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
       6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
       6391 SDHC; succinate dehydrogenase complex subunit C
       6392 SDHD; succinate dehydrogenase complex subunit D
       7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
       4519 CYTB; cytochrome b
       1537 CYC1; cytochrome c1
       7384 UQCRC1; ubiquinol-cytochrome c reductase core protein 1
       7385 UQCRC2; ubiquinol-cytochrome c reductase core protein 2
       7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein
       440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
       7381 UQCRB; ubiquinol-cytochrome c reductase binding protein
       27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
       29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
       10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
       4514 COX3; cytochrome c oxidase subunit III
       4512 COX1; cytochrome c oxidase subunit I
       4513 COX2; cytochrome c oxidase subunit II
       84701 COX4I2; cytochrome c oxidase subunit 4I2
       1327 COX4I1; cytochrome c oxidase subunit 4I1
       9377 COX5A; cytochrome c oxidase subunit 5A
       1329 COX5B; cytochrome c oxidase subunit 5B
       1337 COX6A1; cytochrome c oxidase subunit 6A1
       1339 COX6A2; cytochrome c oxidase subunit 6A2
       1340 COX6B1; cytochrome c oxidase subunit 6B1
       125965 COX6B2; cytochrome c oxidase subunit 6B2
       1345 COX6C; cytochrome c oxidase subunit 6C
       1346 COX7A1; cytochrome c oxidase subunit 7A1
       1347 COX7A2; cytochrome c oxidase subunit 7A2
       9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
       1349 COX7B; cytochrome c oxidase subunit 7B
       170712 COX7B2; cytochrome c oxidase subunit 7B2
       1350 COX7C; cytochrome c oxidase subunit 7C
       341947 COX8C; cytochrome c oxidase subunit 8C
       1351 COX8A; cytochrome c oxidase subunit 8A
       498 ATP5F1A; ATP synthase F1 subunit alpha
       506 ATP5F1B; ATP synthase F1 subunit beta
       509 ATP5F1C; ATP synthase F1 subunit gamma
       513 ATP5F1D; ATP synthase F1 subunit delta
       514 ATP5F1E; ATP synthase F1 subunit epsilon
       4508 ATP6; ATP synthase F0 subunit 6
       515 ATP5PB; ATP synthase peripheral stalk-membrane subunit b
       516 ATP5MC1; ATP synthase membrane subunit c locus 1
       517 ATP5MC2; ATP synthase membrane subunit c locus 2
       518 ATP5MC3; ATP synthase membrane subunit c locus 3
       10476 ATP5PD; ATP synthase peripheral stalk subunit d
       539 ATP5PO; ATP synthase peripheral stalk subunit OSCP
       522 ATP5PF; ATP synthase peripheral stalk subunit F6
       4509 ATP8; ATP synthase F0 subunit 8
       7416 VDAC1; voltage dependent anion channel 1
       7417 VDAC2; voltage dependent anion channel 2
       7419 VDAC3; voltage dependent anion channel 3
       291 SLC25A4; solute carrier family 25 member 4
       292 SLC25A5; solute carrier family 25 member 5
       293 SLC25A6; solute carrier family 25 member 6
       83447 SLC25A31; solute carrier family 25 member 31
       10105 PPIF; peptidylprolyl isomerase F
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
       5687 PSMA6; proteasome 20S subunit alpha 6
       5683 PSMA2; proteasome 20S subunit alpha 2
       5685 PSMA4; proteasome 20S subunit alpha 4
       5688 PSMA7; proteasome 20S subunit alpha 7
       143471 PSMA8; proteasome 20S subunit alpha 8
       5686 PSMA5; proteasome 20S subunit alpha 5
       5682 PSMA1; proteasome 20S subunit alpha 1
       5684 PSMA3; proteasome 20S subunit alpha 3
       5694 PSMB6; proteasome 20S subunit beta 6
       5695 PSMB7; proteasome 20S subunit beta 7
       5691 PSMB3; proteasome 20S subunit beta 3
       5690 PSMB2; proteasome 20S subunit beta 2
       5693 PSMB5; proteasome 20S subunit beta 5
       5689 PSMB1; proteasome 20S subunit beta 1
       5692 PSMB4; proteasome 20S subunit beta 4
       5701 PSMC2; proteasome 26S subunit, ATPase 2
       5700 PSMC1; proteasome 26S subunit, ATPase 1
       5704 PSMC4; proteasome 26S subunit, ATPase 4
       5706 PSMC6; proteasome 26S subunit, ATPase 6
       5702 PSMC3; proteasome 26S subunit, ATPase 3
       5705 PSMC5; proteasome 26S subunit, ATPase 5
       5708 PSMD2; proteasome 26S subunit ubiquitin receptor, non-ATPase 2
       5707 PSMD1; proteasome 26S subunit, non-ATPase 1
       5709 PSMD3; proteasome 26S subunit, non-ATPase 3
       5715 PSMD9; proteasome 26S subunit, non-ATPase 9
       5718 PSMD12; proteasome 26S subunit, non-ATPase 12
       5717 PSMD11; proteasome 26S subunit, non-ATPase 11
       9861 PSMD6; proteasome 26S subunit, non-ATPase 6
       5713 PSMD7; proteasome 26S subunit, non-ATPase 7
       5719 PSMD13; proteasome 26S subunit, non-ATPase 13
       5710 PSMD4; proteasome 26S subunit ubiquitin receptor, non-ATPase 4
       10213 PSMD14; proteasome 26S subunit, non-ATPase 14
       5714 PSMD8; proteasome 26S subunit, non-ATPase 8
       11047 ADRM1; ADRM1 26S proteasome ubiquitin receptor
       7979 SEM1; SEM1 26S proteasome subunit
       4294 MAP3K10; mitogen-activated protein kinase kinase kinase 10
       2081 ERN1; endoplasmic reticulum to nucleus signaling 1
       7186 TRAF2; TNF receptor associated factor 2
       4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       5609 MAP2K7; mitogen-activated protein kinase kinase 7
       2475 MTOR; mechanistic target of rapamycin kinase
       8408 ULK1; unc-51 like autophagy activating kinase 1
       9706 ULK2; unc-51 like autophagy activating kinase 2
       60673 ATG101; autophagy related 101
       9776 ATG13; autophagy related 13
       9821 RB1CC1; RB1 inducible coiled-coil 1
       55626 AMBRA1; autophagy and beclin 1 regulator 1
       8678 BECN1; beclin 1
       441925 BECN2; beclin 2
       30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
       22863 ATG14; autophagy related 14
       29982 NRBF2; nuclear receptor binding factor 2
       5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
       23130 ATG2A; autophagy related 2A
       55102 ATG2B; autophagy related 2B
       26100 WIPI2; WD repeat domain, phosphoinositide interacting 2
       55062 WIPI1; WD repeat domain, phosphoinositide interacting 1
K04644 CLTA; clathrin light chain A
K04645 CLTB; clathrin light chain B
K04646 CLTC; clathrin heavy chain
K04646 CLTC; clathrin heavy chain
K04559 HIP1; huntingtin interacting protein 1
K11824 AP2A; AP-2 complex subunit alpha
K11824 AP2A; AP-2 complex subunit alpha
K11825 AP2B1; AP-2 complex subunit beta-1
K11826 AP2M1; AP-2 complex subunit mu-1
K11827 AP2S1; AP-2 complex subunit sigma-1
K04533 HD; huntingtin
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1; centractin
K16575 ACTR1; centractin
K16576 ACTR10; actin-related protein 10
K04647 HAP1; huntingtin-associated protein 1
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10408 DNAH; dynein axonemal heavy chain
K10410 DNALI; dynein axonemal light intermediate chain 1
K10409 DNAI1; dynein axonemal intermediate chain 1
K11143 DNAI2; dynein axonemal intermediate chain 2
K10411 DNAL1; dynein axonemal light chain 1
K10412 DNAL4; dynein axonemal light chain 4
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K04638 IFT57; intraflagellar transport protein 57
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04560 STX1A; syntaxin 1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K11828 DLG4; discs large protein 4
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K05625 TGM2; transglutaminase 2 [EC:2.3.2.13]
K05614 SLC1A3; solute carrier family 1 (glial high affinity glutamate transporter), member 3
K05613 SLC1A2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
K05003 KCNJ10; potassium inwardly-rectifying channel subfamily J member 10
K09222 REST; RE1-silencing transcription factor
K11644 SIN3A; paired amphipathic helix protein Sin3a
K11829 RCOR1; REST corepressor 1
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K04355 BDNF; brain-derived neurotrophic factor
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K03129 TAF4; transcription initiation factor TFIID subunit 4
K03129 TAF4; transcription initiation factor TFIID subunit 4
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K04684 SP1; transcription factor Sp1
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K11830 TFAM; transcription factor A, mitochondrial
K11831 NRF1; nuclear respiratory factor 1
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K08769 UCP1; solute carrier family 25 (mitochondrial uncoupling protein), member 7
K04451 TP53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K10132 BBC3; Bcl-2-binding component 3
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2; 26S proteasome regulatory subunit T1
K03062 PSMC1; 26S proteasome regulatory subunit T2
K03063 PSMC4; 26S proteasome regulatory subunit T3
K03064 PSMC6; 26S proteasome regulatory subunit T4
K03065 PSMC3; 26S proteasome regulatory subunit T5
K03066 PSMC5; 26S proteasome regulatory subunit T6
K03028 PSMD2; 26S proteasome regulatory subunit N1
K03032 PSMD1; 26S proteasome regulatory subunit N2
K03033 PSMD3; 26S proteasome regulatory subunit N3
K06693 PSMD9; 26S proteasome regulatory subunit N4
K03035 PSMD12; 26S proteasome regulatory subunit N5
K03036 PSMD11; 26S proteasome regulatory subunit N6
K03037 PSMD6; 26S proteasome regulatory subunit N7
K03038 PSMD7; 26S proteasome regulatory subunit N8
K03039 PSMD13; 26S proteasome regulatory subunit N9
K03029 PSMD4; 26S proteasome regulatory subunit N10
K03030 PSMD14; 26S proteasome regulatory subunit N11
K03031 PSMD8; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1; 26 proteasome complex subunit DSS1
K04418 MAP3K10; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN; beclin
K08334 BECN; beclin
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2; autophagy-related protein 18
K17908 WIPI1_2; autophagy-related protein 18
     05017 Spinocerebellar ataxia [PATH:hsa05017]
     05020 Prion disease [PATH:hsa05020]
     05022 Pathways of neurodegeneration - multiple diseases [PATH:hsa05022]
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:hsa01521]
     01524 Platinum drug resistance [PATH:hsa01524]
       1317 SLC31A1; solute carrier family 31 member 1
       540 ATP7B; ATPase copper transporting beta
       538 ATP7A; ATPase copper transporting alpha
       221357 GSTA5; glutathione S-transferase alpha 5
       2939 GSTA2; glutathione S-transferase alpha 2
       2941 GSTA4; glutathione S-transferase alpha 4
       119391 GSTO2; glutathione S-transferase omega 2
       2948 GSTM4; glutathione S-transferase mu 4
       2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
       2952 GSTT1; glutathione S-transferase theta 1
       2947 GSTM3; glutathione S-transferase mu 3
       4257 MGST1; microsomal glutathione S-transferase 1
       4259 MGST3; microsomal glutathione S-transferase 3
       2944 GSTM1; glutathione S-transferase mu 1
       2949 GSTM5; glutathione S-transferase mu 5
       4258 MGST2; microsomal glutathione S-transferase 2
       2938 GSTA1; glutathione S-transferase alpha 1
       2946 GSTM2; glutathione S-transferase mu 2
       2940 GSTA3; glutathione S-transferase alpha 3
       9446 GSTO1; glutathione S-transferase omega 1
       653689 GSTT2B; glutathione S-transferase theta 2B
       2950 GSTP1; glutathione S-transferase pi 1
       1244 ABCC2; ATP binding cassette subfamily C member 2
       5429 POLH; DNA polymerase eta
       5980 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       4292 MLH1; mutL homolog 1
       7507 XPA; XPA, DNA damage recognition and repair factor
       2067 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       7155 TOP2B; DNA topoisomerase II beta
       7153 TOP2A; DNA topoisomerase II alpha
       672 BRCA1; BRCA1 DNA repair associated
       472 ATM; ATM serine/threonine kinase
       7157 TP53; tumor protein p53
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       4193 MDM2; MDM2 proto-oncogene
       355 FAS; Fas cell surface death receptor
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       27113 BBC3; BCL2 binding component 3
       356 FASLG; Fas ligand
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       836 CASP3; caspase 3
       637 BID; BH3 interacting domain death agonist
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       332 BIRC5; baculoviral IAP repeat containing 5
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       572 BAD; BCL2 associated agonist of cell death
       598 BCL2L1; BCL2 like 1
       596 BCL2; BCL2 apoptosis regulator
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:hsa01523]
     01522 Endocrine resistance [PATH:hsa01522]
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 18, 2024