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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:hsa04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:hsa04012]
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04014 Ras signaling pathway [PATH:hsa04014]
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04015 Rap1 signaling pathway [PATH:hsa04015]
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04310 Wnt signaling pathway [PATH:hsa04310]
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04330 Notch signaling pathway [PATH:hsa04330]
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04340 Hedgehog signaling pathway [PATH:hsa04340]
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:hsa04350]
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8646 CHRD; chordin
9241 NOG; noggin
4681 NBL1; NBL1, DAN family BMP antagonist
100532736 MICOS10-NBL1; MICOS10-NBL1 readthrough
26585 GREM1; gremlin 1, DAN family BMP antagonist
64388 GREM2; gremlin 2, DAN family BMP antagonist
7057 THBS1; thrombospondin 1
1634 DCN; decorin
2331 FMOD; fibromodulin
10637 LEFTY1; left-right determination factor 1
7044 LEFTY2; left-right determination factor 2
10468 FST; follistatin
650 BMP2; bone morphogenetic protein 2
652 BMP4; bone morphogenetic protein 4
654 BMP6; bone morphogenetic protein 6
3625 INHBB; inhibin subunit beta B
7018 TF; transferrin
653 BMP5; bone morphogenetic protein 5
655 BMP7; bone morphogenetic protein 7
656 BMP8B; bone morphogenetic protein 8b
353500 BMP8A; bone morphogenetic protein 8a
8200 GDF5; growth differentiation factor 5
392255 GDF6; growth differentiation factor 6
151449 GDF7; growth differentiation factor 7
268 AMH; anti-Mullerian hormone
3458 IFNG; interferon gamma
7124 TNF; tumor necrosis factor
79875 THSD4; thrombospondin type 1 domain containing 4
2200 FBN1; fibrillin 1
4052 LTBP1; latent transforming growth factor beta binding protein 1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
3624 INHBA; inhibin subunit beta A
3626 INHBC; inhibin subunit beta C
83729 INHBE; inhibin subunit beta E
4838 NODAL; nodal growth differentiation factor
657 BMPR1A; bone morphogenetic protein receptor type 1A
658 BMPR1B; bone morphogenetic protein receptor type 1B
90 ACVR1; activin A receptor type 1
659 BMPR2; bone morphogenetic protein receptor type 2
92 ACVR2A; activin A receptor type 2A
148738 HJV; hemojuvelin BMP co-receptor
4756 NEO1; neogenin 1
3077 HFE; homeostatic iron regulator
7036 TFR2; transferrin receptor 2
7037 TFRC; transferrin receptor
56963 RGMA; repulsive guidance molecule BMP co-receptor a
285704 RGMB; repulsive guidance molecule BMP co-receptor b
269 AMHR2; anti-Mullerian hormone receptor type 2
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
2014 EMP3; epithelial membrane protein 3 (MAM blood group)
2615 LRRC32; leucine rich repeat containing 32
375387 NRROS; negative regulator of reactive oxygen species
91 ACVR1B; activin A receptor type 1B
93 ACVR2B; activin A receptor type 2B
130399 ACVR1C; activin A receptor type 1C
3547 IGSF1; immunoglobulin superfamily member 1
25805 BAMBI; BMP and activin membrane bound inhibitor
4086 SMAD1; SMAD family member 1
4090 SMAD5; SMAD family member 5
4093 SMAD9; SMAD family member 9
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
4091 SMAD6; SMAD family member 6
4092 SMAD7; SMAD family member 7
57154 SMURF1; SMAD specific E3 ubiquitin protein ligase 1
64750 SMURF2; SMAD specific E3 ubiquitin protein ligase 2
9372 ZFYVE9; zinc finger FYVE-type containing 9
9765 ZFYVE16; zinc finger FYVE-type containing 16
9978 RBX1; ring-box 1
8454 CUL1; cullin 1
6500 SKP1; S-phase kinase associated protein 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
57817 HAMP; hepcidin antimicrobial peptide
3397 ID1; inhibitor of DNA binding 1
3398 ID2; inhibitor of DNA binding 2
3399 ID3; inhibitor of DNA binding 3
3400 ID4; inhibitor of DNA binding 4
5933 RBL1; RB transcriptional corepressor like 1
1874 E2F4; E2F transcription factor 4
1875 E2F5; E2F transcription factor 5
7027 TFDP1; transcription factor Dp-1
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
6667 SP1; Sp1 transcription factor
6498 SKIL; SKI like proto-oncogene
6497 SKI; SKI proto-oncogene
25942 SIN3A; SIN3 transcription regulator family member A
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
9611 NCOR1; nuclear receptor corepressor 1
7050 TGIF1; TGFB induced factor homeobox 1
60436 TGIF2; TGFB induced factor homeobox 2
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
5308 PITX2; paired like homeodomain 2
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K04657 CHRD; chordin
K04658 NOG; noggin
K19558 NBL1; neuroblastoma suppressor of tumorigenicity 1
K19558 NBL1; neuroblastoma suppressor of tumorigenicity 1
K23318 GREM; gremlin
K23318 GREM; gremlin
K16857 THBS1; thrombospondin 1
K04660 DCN; decorin
K08121 FMOD; fibromodulin
K04668 LEFTY; left-right determination factor
K04668 LEFTY; left-right determination factor
K04661 FST; follistatin
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K16620 BMP6; bone morphogenetic protein 6
K22687 INHBB; inhibin beta B chain
K14736 TF; transferrin
K04663 BMP5; bone morphogenetic protein 5
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04687 IFNG; interferon gamma
K03156 TNF; tumor necrosis factor superfamily, member 2
K23377 THSD4; thrombospondin type-1 domain-containing protein 4
K06825 FBN1; fibrillin 1
K19559 LTBP1; latent transforming growth factor beta binding protein 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04667 INHBA; inhibin beta A chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04666 NODAL; nodal
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K23100 HJV; hemojuvelin
K06766 NEO1; neogenin
K26535 HFE; hereditary hemochromatosis protein
K23910 TFR2; transferrin receptor protein 2
K06503 TFRC; transferrin receptor
K23096 RGMA; repulsive guidance molecule A
K06847 RGMB; RGM domain family member B
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K26257 EMP3; epithelial membrane protein 3
K26316 LRRC32; transforming growth factor beta activator LRRC32
K26317 NRROS; transforming growth factor beta activator LRRC33
K13567 ACVR1B; activin receptor type-1B [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K13568 ACVR1C; activin receptor type-1C [EC:2.7.11.30]
K26168 IGSF1; immunoglobulin superfamily member 1
K10162 BAMBI; BMP and activin membrane-bound inhibitor
K04676 SMAD1; mothers against decapentaplegic homolog 1
K16790 SMAD5; mothers against decapentaplegic homolog 5
K16791 SMAD9; mothers against decapentaplegic homolog 9
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04677 SMAD6; mothers against decapentaplegic homolog 6
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K04679 MADHIP; MAD, mothers against decapentaplegic interacting protein
K04679 MADHIP; MAD, mothers against decapentaplegic interacting protein
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03347 CUL1; cullin 1
K03094 SKP1; S-phase kinase-associated protein 1
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K23106 HAMP; hepcidin
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K17694 ID3; DNA-binding protein inhibitor ID3
K17695 ID4; DNA-binding protein inhibitor ID4
K04681 RBL1; retinoblastoma-like protein 1
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K18499 SKIL; Ski-like protein
K26503 SKI; Ski oncogene
K11644 SIN3A; paired amphipathic helix protein Sin3a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K04650 NCOR1; nuclear receptor co-repressor 1
K19383 TGIF1; homeobox protein TGIF1
K19553 TGIF2; homeobox protein TGIF2
K04377 MYC; Myc proto-oncogene protein
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K04686 PITX2; paired-like homeodomain transcription factor 2
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04390 Hippo signaling pathway [PATH:hsa04390]
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286204 CRB2; crumbs cell polarity complex component 2
23418 CRB1; crumbs cell polarity complex component 1
56288 PARD3; par-3 family cell polarity regulator
50855 PARD6A; par-6 family cell polarity regulator alpha
84552 PARD6G; par-6 family cell polarity regulator gamma
84612 PARD6B; par-6 family cell polarity regulator beta
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
10207 PATJ; PATJ crumbs cell polarity complex component
64398 PALS1; protein associated with LIN7 1, MAGUK p55 family member
154796 AMOT; angiomotin
10413 YAP1; Yes1 associated transcriptional regulator
25937 WWTR1; WW domain containing transcription regulator 1
999 CDH1; cadherin 1
8994 LIMD1; LIM domain containing 1
84962 AJUBA; ajuba LIM protein
126374 WTIP; WT1 interacting protein
4771 NF2; NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
23286 WWC1; WW and C2 domain containing 1
79981 FRMD1; FERM domain containing 1
122786 FRMD6; FERM domain containing 6
60485 SAV1; salvador family WW domain containing protein 1
6788 STK3; serine/threonine kinase 3
166824 RASSF6; Ras association domain family member 6
11186 RASSF1; Ras association domain family member 1
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
26524 LATS2; large tumor suppressor kinase 2
9113 LATS1; large tumor suppressor kinase 1
55233 MOB1A; MOB kinase activator 1A
92597 MOB1B; MOB kinase activator 1B
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
7159 TP53BP2; tumor protein p53 binding protein 2
3993 LLGL2; LLGL scribble cell polarity complex component 2
3996 LLGL1; LLGL scribble cell polarity complex component 1
23513 SCRIB; scribble planar cell polarity protein
1739 DLG1; discs large MAGUK scaffold protein 1
1740 DLG2; discs large MAGUK scaffold protein 2
1741 DLG3; discs large MAGUK scaffold protein 3
1742 DLG4; discs large MAGUK scaffold protein 4
9231 DLG5; discs large MAGUK scaffold protein 5
1453 CSNK1D; casein kinase 1 delta
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
23291 FBXW11; F-box and WD repeat domain containing 11
7161 TP73; tumor protein p73
27113 BBC3; BCL2 binding component 3
7003 TEAD1; TEA domain transcription factor 1
7004 TEAD4; TEA domain transcription factor 4
7005 TEAD3; TEA domain transcription factor 3
8463 TEAD2; TEA domain transcription factor 2
1490 CCN2; cellular communication network factor 2
2736 GLI2; GLI family zinc finger 2
374 AREG; amphiregulin
332 BIRC5; baculoviral IAP repeat containing 5
174 AFP; alpha fetoprotein
3689 ITGB2; integrin subunit beta 2
2246 FGF1; fibroblast growth factor 1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4092 SMAD7; SMAD family member 7
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
5054 SERPINE1; serpin family E member 1
650 BMP2; bone morphogenetic protein 2
652 BMP4; bone morphogenetic protein 4
653 BMP5; bone morphogenetic protein 5
654 BMP6; bone morphogenetic protein 6
655 BMP7; bone morphogenetic protein 7
656 BMP8B; bone morphogenetic protein 8b
353500 BMP8A; bone morphogenetic protein 8a
8200 GDF5; growth differentiation factor 5
392255 GDF6; growth differentiation factor 6
151449 GDF7; growth differentiation factor 7
268 AMH; anti-Mullerian hormone
657 BMPR1A; bone morphogenetic protein receptor type 1A
658 BMPR1B; bone morphogenetic protein receptor type 1B
659 BMPR2; bone morphogenetic protein receptor type 2
4086 SMAD1; SMAD family member 1
3397 ID1; inhibitor of DNA binding 1
3398 ID2; inhibitor of DNA binding 2
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
2932 GSK3B; glycogen synthase kinase 3 beta
1499 CTNNB1; catenin beta 1
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
8312 AXIN1; axin 1
8313 AXIN2; axin 2
85407 NKD1; NKD inhibitor of WNT signaling pathway 1
85409 NKD2; NKD inhibitor of WNT signaling pathway 2
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
6657 SOX2; SRY-box transcription factor 2
6591 SNAI2; snail family transcriptional repressor 2
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
71 ACTG1; actin gamma 1
60 ACTB; actin beta
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
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K16681 CRB; protein crumbs
K16681 CRB; protein crumbs
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06092 INADL; InaD-like protein
K06091 MPP5; MAGUK p55 subfamily member 5
K16819 AMOT; angiomotin
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K16686 SAV1; scaffold protein salvador
K04412 STK3; serine/threonine kinase 3
K09854 RASSF6; Ras association domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16823 TP53BP2; apoptosis-stimulating of p53 protein 2
K06094 LLGL; lethal(2) giant larvae protein
K06094 LLGL; lethal(2) giant larvae protein
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K11828 DLG4; discs large protein 4
K24050 DLG5; discs large protein 5
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10148 TP73; tumor protein p73
K10132 BBC3; Bcl-2-binding component 3
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K16798 GLI2; zinc finger protein GLI2
K09782 AREG; amphiregulin
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16144 AFP; alpha-fetoprotein
K06464 ITGB2; integrin beta 2
K18496 FGF1; fibroblast growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03982 SERPINE1; plasminogen activator inhibitor 1
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16796 SOX2; transcription factor SOX2 (SOX group B)
K05706 SNAI2; snail 2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
|
04370 VEGF signaling pathway [PATH:hsa04370]
|
04371 Apelin signaling pathway [PATH:hsa04371]
|
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
55811 ADCY10; adenylate cyclase 10
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
3991 LIPE; lipase E, hormone sensitive type
8862 APLN; apelin
100506013 APELA; apelin receptor early endogenous ligand
187 APLNR; apelin receptor
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
6261 RYR1; ryanodine receptor 1
6262 RYR2; ryanodine receptor 2
6263 RYR3; ryanodine receptor 3
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
4842 NOS1; nitric oxide synthase 1
4843 NOS2; nitric oxide synthase 2
4846 NOS3; nitric oxide synthase 3
5581 PRKCE; protein kinase C epsilon
6548 SLC9A1; solute carrier family 9 member A1
6546 SLC8A1; solute carrier family 8 member A1
6543 SLC8A2; solute carrier family 8 member A2
6547 SLC8A3; solute carrier family 8 member A3
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
4633 MYL2; myosin light chain 2
4634 MYL3; myosin light chain 3
4635 MYL4; myosin light chain 4
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
6194 RPS6; ribosomal protein S6
5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
1958 EGR1; early growth response 1
6696 SPP1; secreted phosphoprotein 1
182 JAG1; jagged canonical Notch ligand 1
4854 NOTCH3; notch receptor 3
595 CCND1; cyclin D1
5140 PDE3B; phosphodiesterase 3B
5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
8678 BECN1; beclin 1
441925 BECN2; beclin 2
440738 MAP1LC3C; microtubule associated protein 1 light chain 3 gamma
81631 MAP1LC3B; microtubule associated protein 1 light chain 3 beta
84557 MAP1LC3A; microtubule associated protein 1 light chain 3 alpha
643246 MAP1LC3B2; microtubule associated protein 1 light chain 3 beta 2
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
5346 PLIN1; perilipin 1
10891 PPARGC1A; PPARG coactivator 1 alpha
7350 UCP1; uncoupling protein 1
4899 NRF1; nuclear respiratory factor 1
7019 TFAM; transcription factor A, mitochondrial
10365 KLF2; KLF transcription factor 2
8877 SPHK1; sphingosine kinase 1
56848 SPHK2; sphingosine kinase 2
10672 GNA13; G protein subunit alpha 13
814 CAMK4; calcium/calmodulin dependent protein kinase IV
9759 HDAC4; histone deacetylase 4
10014 HDAC5; histone deacetylase 5
4205 MEF2A; myocyte enhancer factor 2A
4207 BORCS8-MEF2B; BORCS8-MEF2B readthrough
100271849 MEF2B; myocyte enhancer factor 2B
4208 MEF2C; myocyte enhancer factor 2C
4209 MEF2D; myocyte enhancer factor 2D
7046 TGFBR1; transforming growth factor beta receptor 1
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
59 ACTA2; actin alpha 2, smooth muscle
999 CDH1; cadherin 1
1490 CCN2; cellular communication network factor 2
185 AGTR1; angiotensin II receptor type 1
5054 SERPINE1; serpin family E member 1
5327 PLAT; plasminogen activator, tissue type
|
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K05225 APLN; apelin
K25355 APELA; apelin receptor early endogenous ligand
K04174 APLNR; apelin receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K10351 MYL2; myosin regulatory light chain 2
K12749 MYL3; myosin light chain 3
K12750 MYL4; myosin light chain 4
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K09203 EGR1; early growth response protein 1
K06250 SPP1; secreted phosphoprotein 1
K06052 JAG1; jagged-1
K20995 NOTCH3; Notch 3
K04503 CCND1; G1/S-specific cyclin-D1
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K08334 BECN; beclin
K08334 BECN; beclin
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K08768 PLIN1; perilipin-1
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K08769 UCP1; solute carrier family 25 (mitochondrial uncoupling protein), member 7
K11831 NRF1; nuclear respiratory factor 1
K11830 TFAM; transcription factor A, mitochondrial
K17845 KLF2; krueppel-like factor 2
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K09262 MEF2D; MADS-box transcription enhancer factor 2D
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K12313 ACTA2; actin, aortic smooth muscle
K05689 CDH1; cadherin 1, type 1, E-cadherin
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K04166 AGTR1; angiotensin II receptor type 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
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04630 JAK-STAT signaling pathway [PATH:hsa04630]
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04064 NF-kappa B signaling pathway [PATH:hsa04064]
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04668 TNF signaling pathway [PATH:hsa04668]
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04066 HIF-1 signaling pathway [PATH:hsa04066]
|
04068 FoxO signaling pathway [PATH:hsa04068]
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04020 Calcium signaling pathway [PATH:hsa04020]
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04070 Phosphatidylinositol signaling system [PATH:hsa04070]
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04072 Phospholipase D signaling pathway [PATH:hsa04072]
|
04071 Sphingolipid signaling pathway [PATH:hsa04071]
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04024 cAMP signaling pathway [PATH:hsa04024]
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04022 cGMP-PKG signaling pathway [PATH:hsa04022]
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04151 PI3K-Akt signaling pathway [PATH:hsa04151]
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04152 AMPK signaling pathway [PATH:hsa04152]
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04150 mTOR signaling pathway [PATH:hsa04150]
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04075 Plant hormone signal transduction
|
|
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09133 Signaling molecules and interaction
|
|
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09140 Cellular Processes
|
|
|
09141 Transport and catabolism
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04144 Endocytosis [PATH:hsa04144]
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382 ARF6; ADP ribosylation factor 6
23396 PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
8394 PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
8395 PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta
138429 PIP5KL1; phosphatidylinositol-4-phosphate 5-kinase like 1
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
1759 DNM1; dynamin 1
26052 DNM3; dynamin 3
1785 DNM2; dynamin 2
1211 CLTA; clathrin light chain A
1212 CLTB; clathrin light chain B
1213 CLTC; clathrin heavy chain
8218 CLTCL1; clathrin heavy chain like 1
161 AP2A2; adaptor related protein complex 2 subunit alpha 2
160 AP2A1; adaptor related protein complex 2 subunit alpha 1
163 AP2B1; adaptor related protein complex 2 subunit beta 1
1173 AP2M1; adaptor related protein complex 2 subunit mu 1
1175 AP2S1; adaptor related protein complex 2 subunit sigma 1
30846 EHD2; EH domain containing 2
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
9372 ZFYVE9; zinc finger FYVE-type containing 9
9765 ZFYVE16; zinc finger FYVE-type containing 16
5371 PML; PML nuclear body scaffold
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
7037 TFRC; transferrin receptor
1956 EGFR; epidermal growth factor receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
3480 IGF1R; insulin like growth factor 1 receptor
867 CBL; Cbl proto-oncogene
868 CBLB; Cbl proto-oncogene B
23624 CBLC; Cbl proto-oncogene C
30011 SH3KBP1; SH3 domain containing kinase binding protein 1
6457 SH3GL3; SH3 domain containing GRB2 like 3, endophilin A3
6456 SH3GL2; SH3 domain containing GRB2 like 2, endophilin A1
6455 SH3GL1; SH3 domain containing GRB2 like 1, endophilin A2
51100 SH3GLB1; SH3 domain containing GRB2 like, endophilin B1
56904 SH3GLB2; SH3 domain containing GRB2 like, endophilin B2
273 AMPH; amphiphysin
274 BIN1; bridging integrator 1
29924 EPN1; epsin 1
55040 EPN3; epsin 3
22905 EPN2; epsin 2
2060 EPS15; epidermal growth factor receptor pathway substrate 15
58513 EPS15L1; epidermal growth factor receptor pathway substrate 15 like 1
23111 SPART; spartin
4734 NEDD4; NEDD4 E3 ubiquitin protein ligase
23327 NEDD4L; NEDD4 like E3 ubiquitin protein ligase
4193 MDM2; MDM2 proto-oncogene
7189 TRAF6; TNF receptor associated factor 6
10193 RNF41; ring finger protein 41
83737 ITCH; itchy E3 ubiquitin protein ligase
57154 SMURF1; SMAD specific E3 ubiquitin protein ligase 1
64750 SMURF2; SMAD specific E3 ubiquitin protein ligase 2
11059 WWP1; WW domain containing E3 ubiquitin protein ligase 1
3949 LDLR; low density lipoprotein receptor
26119 LDLRAP1; low density lipoprotein receptor adaptor protein 1
1601 DAB2; DAB adaptor protein 2
1234 CCR5; C-C motif chemokine receptor 5
3577 CXCR1; C-X-C motif chemokine receptor 1
3579 CXCR2; C-X-C motif chemokine receptor 2
7852 CXCR4; C-X-C motif chemokine receptor 4
131890 GRK7; G protein-coupled receptor kinase 7
6011 GRK1; G protein-coupled receptor kinase 1
156 GRK2; G protein-coupled receptor kinase 2
157 GRK3; G protein-coupled receptor kinase 3
2868 GRK4; G protein-coupled receptor kinase 4
2869 GRK5; G protein-coupled receptor kinase 5
2870 GRK6; G protein-coupled receptor kinase 6
408 ARRB1; arrestin beta 1
409 ARRB2; arrestin beta 2
8976 WASL; WASP like actin nucleation promoting factor
10097 ACTR2; actin related protein 2
57180 ACTR3B; actin related protein 3B
653857 ACTR3C; actin related protein 3C
10096 ACTR3; actin related protein 3
10095 ARPC1B; actin related protein 2/3 complex subunit 1B
10552 ARPC1A; actin related protein 2/3 complex subunit 1A
10109 ARPC2; actin related protein 2/3 complex subunit 2
10094 ARPC3; actin related protein 2/3 complex subunit 3
10093 ARPC4; actin related protein 2/3 complex subunit 4
10092 ARPC5; actin related protein 2/3 complex subunit 5
81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
147179 WIPF2; WAS/WASL interacting protein family member 2
7456 WIPF1; WAS/WASL interacting protein family member 1
644150 WIPF3; WAS/WASL interacting protein family member 3
3312 HSPA8; heat shock protein family A (Hsp70) member 8
3303 HSPA1A; heat shock protein family A (Hsp70) member 1A
3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like
3304 HSPA1B; heat shock protein family A (Hsp70) member 1B
3310 HSPA6; heat shock protein family A (Hsp70) member 6
9829 DNAJC6; DnaJ heat shock protein family (Hsp40) member C6
23325 WASHC4; WASH complex subunit 4
9897 WASHC5; WASH complex subunit 5
253725 WASHC2C; WASH complex subunit 2C
387680 WASHC2A; WASH complex subunit 2A
100287171 WASHC1; WASH complex subunit 1
51019 WASHC3; WASH complex subunit 3
829 CAPZA1; capping actin protein of muscle Z-line subunit alpha 1
830 CAPZA2; capping actin protein of muscle Z-line subunit alpha 2
93661 CAPZA3; capping actin protein of muscle Z-line subunit alpha 3
832 CAPZB; capping actin protein of muscle Z-line subunit beta
51699 VPS29; VPS29 retromer complex component
112936 VPS26B; VPS26 retromer complex component B
9559 VPS26A; VPS26 retromer complex component A
55737 VPS35; VPS35 retromer complex component
29934 SNX12; sorting nexin 12
8724 SNX3; sorting nexin 3
9101 USP8; ubiquitin specific peptidase 8
10617 STAMBP; STAM binding protein
7879 RAB7A; RAB7A, member RAS oncogene family
9146 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
10254 STAM2; signal transducing adaptor molecule 2
8027 STAM; signal transducing adaptor molecule
7251 TSG101; tumor susceptibility 101
93343 MVB12A; multivesicular body subunit 12A
89853 MVB12B; multivesicular body subunit 12B
51160 VPS28; VPS28 subunit of ESCRT-I
155382 VPS37D; VPS37D subunit of ESCRT-I
137492 VPS37A; VPS37A subunit of ESCRT-I
79720 VPS37B; VPS37B subunit of ESCRT-I
55048 VPS37C; VPS37C subunit of ESCRT-I
11267 SNF8; SNF8 subunit of ESCRT-II
51028 VPS36; vacuolar protein sorting 36 homolog
84313 VPS25; vacuolar protein sorting 25 homolog
79643 CHMP6; charged multivesicular body protein 6
128866 CHMP4B; charged multivesicular body protein 4B
29082 CHMP4A; charged multivesicular body protein 4A
92421 CHMP4C; charged multivesicular body protein 4C
51652 CHMP3; charged multivesicular body protein 3
100526767 RNF103-CHMP3; RNF103-CHMP3 readthrough
27243 CHMP2A; charged multivesicular body protein 2A
25978 CHMP2B; charged multivesicular body protein 2B
91782 CHMP7; charged multivesicular body protein 7
9525 VPS4B; vacuolar protein sorting 4 homolog B
27183 VPS4A; vacuolar protein sorting 4 homolog A
51534 VTA1; vesicle trafficking 1
57132 CHMP1B; charged multivesicular body protein 1B
5119 CHMP1A; charged multivesicular body protein 1A
51510 CHMP5; charged multivesicular body protein 5
9798 IST1; IST1 factor associated with ESCRT-III
10015 PDCD6IP; programmed cell death 6 interacting protein
51324 SPG21; SPG21 abhydrolase domain containing, maspardin
3482 IGF2R; insulin like growth factor 2 receptor
6642 SNX1; sorting nexin 1
6643 SNX2; sorting nexin 2
254122 SNX32; sorting nexin 32
27131 SNX5; sorting nexin 5
58533 SNX6; sorting nexin 6
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
3265 HRAS; HRas proto-oncogene, GTPase
3559 IL2RA; interleukin 2 receptor subunit alpha
3560 IL2RB; interleukin 2 receptor subunit beta
3561 IL2RG; interleukin 2 receptor subunit gamma
387 RHOA; ras homolog family member A
3105 HLA-A; major histocompatibility complex, class I, A
3106 HLA-B; major histocompatibility complex, class I, B
3107 HLA-C; major histocompatibility complex, class I, C
3134 HLA-F; major histocompatibility complex, class I, F
3135 HLA-G; major histocompatibility complex, class I, G
3133 HLA-E; major histocompatibility complex, class I, E
2348 FOLR1; folate receptor alpha
2350 FOLR2; folate receptor beta
2352 FOLR3; folate receptor gamma
857 CAV1; caveolin 1
858 CAV2; caveolin 2
859 CAV3; caveolin 3
30845 EHD3; EH domain containing 3
30844 EHD4; EH domain containing 4
8411 EEA1; early endosome antigen 1
5868 RAB5A; RAB5A, member RAS oncogene family
5869 RAB5B; RAB5B, member RAS oncogene family
5878 RAB5C; RAB5C, member RAS oncogene family
9135 RABEP1; rabaptin, RAB GTPase binding effector protein 1
64145 RBSN; rabenosyn, RAB effector
5867 RAB4A; RAB4A, member RAS oncogene family
80230 RUFY1; RUN and FYVE domain containing 1
55680 RUFY2; RUN and FYVE domain containing 2
10938 EHD1; EH domain containing 1
11311 VPS45; vacuolar protein sorting 45 homolog
8723 SNX4; sorting nexin 4
57403 RAB22A; RAB22A, member RAS oncogene family
11031 RAB31; RAB31, member RAS oncogene family
10890 RAB10; RAB10, member RAS oncogene family
4218 RAB8A; RAB8A, member RAS oncogene family
11021 RAB35; RAB35, member RAS oncogene family
8766 RAB11A; RAB11A, member RAS oncogene family
9230 RAB11B; RAB11B, member RAS oncogene family
22841 RAB11FIP2; RAB11 family interacting protein 2
80223 RAB11FIP1; RAB11 family interacting protein 1
26056 RAB11FIP5; RAB11 family interacting protein 5
118813 ZFYVE27; zinc finger FYVE-type containing 27
3798 KIF5A; kinesin family member 5A
3799 KIF5B; kinesin family member 5B
3800 KIF5C; kinesin family member 5C
84440 RAB11FIP4; RAB11 family interacting protein 4
9727 RAB11FIP3; RAB11 family interacting protein 3
56288 PARD3; par-3 family cell polarity regulator
50855 PARD6A; par-6 family cell polarity regulator alpha
84552 PARD6G; par-6 family cell polarity regulator gamma
84612 PARD6B; par-6 family cell polarity regulator beta
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
998 CDC42; cell division cycle 42
64744 SMAP2; small ArfGAP2
60682 SMAP1; small ArfGAP 1
28964 GIT1; GIT ArfGAP 1
9815 GIT2; GIT ArfGAP 2
50807 ASAP1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
55616 ASAP3; ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
8853 ASAP2; ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
116983 ACAP3; ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
23527 ACAP2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
9744 ACAP1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
116985 ARAP1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
116984 ARAP2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
64411 ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
116987 AGAP1; ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
116988 AGAP3; ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
119016 AGAP4; ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
414189 AGAP6; ArfGAP with GTPase domain, ankyrin repeat and PH domain 6
642517 AGAP9; ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
729092 AGAP5; ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
116986 AGAP2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
55738 ARFGAP1; ADP ribosylation factor GTPase activating protein 1
26286 ARFGAP3; ADP ribosylation factor GTPase activating protein 3
84364 ARFGAP2; ADP ribosylation factor GTPase activating protein 2
23362 PSD3; pleckstrin and Sec7 domain containing 3
23550 PSD4; pleckstrin and Sec7 domain containing 4
5662 PSD; pleckstrin and Sec7 domain containing
84249 PSD2; pleckstrin and Sec7 domain containing 2
23096 IQSEC2; IQ motif and Sec7 domain ArfGEF 2
9922 IQSEC1; IQ motif and Sec7 domain ArfGEF 1
440073 IQSEC3; IQ motif and Sec7 domain ArfGEF 3
9265 CYTH3; cytohesin 3
27128 CYTH4; cytohesin 4
9266 CYTH2; cytohesin 2
9267 CYTH1; cytohesin 1
10564 ARFGEF2; ADP ribosylation factor guanine nucleotide exchange factor 2
10565 ARFGEF1; ADP ribosylation factor guanine nucleotide exchange factor 1
8729 GBF1; golgi brefeldin A resistant guanine nucleotide exchange factor 1
375 ARF1; ADP ribosylation factor 1
377 ARF3; ADP ribosylation factor 3
378 ARF4; ADP ribosylation factor 4
381 ARF5; ADP ribosylation factor 5
|
K07941 ARF6; ADP-ribosylation factor 6
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K13712 PIP5KL1; phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5]
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5]
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K04644 CLTA; clathrin light chain A
K04645 CLTB; clathrin light chain B
K04646 CLTC; clathrin heavy chain
K04646 CLTC; clathrin heavy chain
K11824 AP2A; AP-2 complex subunit alpha
K11824 AP2A; AP-2 complex subunit alpha
K11825 AP2B1; AP-2 complex subunit beta-1
K11826 AP2M1; AP-2 complex subunit mu-1
K11827 AP2S1; AP-2 complex subunit sigma-1
K12469 EHD2; EH domain-containing protein 2
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04679 MADHIP; MAD, mothers against decapentaplegic interacting protein
K04679 MADHIP; MAD, mothers against decapentaplegic interacting protein
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K06503 TFRC; transferrin receptor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
K12470 SH3KBP1; SH3 domain-containing kinase-binding protein 1
K11247 SH3GL; endophilin-A
K11247 SH3GL; endophilin-A
K11247 SH3GL; endophilin-A
K11248 SH3GLB1; endophilin-B1
K21269 SH3GLB2; endophilin-B2
K12562 AMPH; amphiphysin
K12562 AMPH; amphiphysin
K12471 EPN; epsin
K12471 EPN; epsin
K12471 EPN; epsin
K12472 EPS15; epidermal growth factor receptor substrate 15
K12472 EPS15; epidermal growth factor receptor substrate 15
K19366 SPG20; spartin
K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
K12473 LDLR; low-density lipoprotein receptor
K12474 LDLRAP1; low density lipoprotein receptor adapter protein 1
K12475 DAB2; disabled homolog 2
K04180 CCR5; C-C chemokine receptor type 5
K04175 CXCR1; C-X-C chemokine receptor type 1
K05050 CXCR2; C-X-C chemokine receptor type 2
K04189 CXCR4; C-X-C chemokine receptor type 4
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K19475 WIPF; WAS/WASL-interacting protein
K19475 WIPF; WAS/WASL-interacting protein
K19475 WIPF; WAS/WASL-interacting protein
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K09526 DNAJC6; DnaJ homolog subfamily C member 6
K18465 MRT43; WASH complex subunit 7
K18464 RTSC; WASH complex subunit strumpellin
K18462 FAM21; WASH complex subunit FAM21
K18462 FAM21; WASH complex subunit FAM21
K18461 WASH1; WAS protein family homolog 1
K18463 CCDC53; WASH complex subunit CCDC53
K10364 CAPZA; F-actin-capping protein subunit alpha
K10364 CAPZA; F-actin-capping protein subunit alpha
K10364 CAPZA; F-actin-capping protein subunit alpha
K10365 CAPZB; F-actin-capping protein subunit beta
K18467 VPS29; vacuolar protein sorting-associated protein 29
K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
K18468 VPS35; vacuolar protein sorting-associated protein 35
K17918 SNX3_12; sorting nexin-3/12
K17918 SNX3_12; sorting nexin-3/12
K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
K07897 RAB7A; Ras-related protein Rab-7A
K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
K04705 STAM; signal transducing adaptor molecule
K04705 STAM; signal transducing adaptor molecule
K12183 TSG101; ESCRT-I complex subunit TSG101
K12186 FAM125; ESCRT-I complex subunit MVB12
K12186 FAM125; ESCRT-I complex subunit MVB12
K12184 VPS28; ESCRT-I complex subunit VPS28
K12185 VPS37; ESCRT-I complex subunit VPS37
K12185 VPS37; ESCRT-I complex subunit VPS37
K12185 VPS37; ESCRT-I complex subunit VPS37
K12185 VPS37; ESCRT-I complex subunit VPS37
K12188 SNF8; ESCRT-II complex subunit VPS22
K12190 VPS36; ESCRT-II complex subunit VPS36
K12189 VPS25; ESCRT-II complex subunit VPS25
K12195 CHMP6; charged multivesicular body protein 6
K12194 CHMP4A_B; charged multivesicular body protein 4A/B
K12194 CHMP4A_B; charged multivesicular body protein 4A/B
K24782 CHMP4C; charged multivesicular body protein 4C
K12193 VPS24; charged multivesicular body protein 3
K12193 VPS24; charged multivesicular body protein 3
K12191 CHMP2A; charged multivesicular body protein 2A
K12192 CHMP2B; charged multivesicular body protein 2B
K15053 CHMP7; charged multivesicular body protein 7
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12199 VTA1; vacuolar protein sorting-associated protein VTA1
K12197 CHMP1; charged multivesicular body protein 1
K12197 CHMP1; charged multivesicular body protein 1
K12198 CHMP5; charged multivesicular body protein 5
K19476 IST1; vacuolar protein sorting-associated protein IST1
K12200 PDCD6IP; programmed cell death 6-interacting protein
K19367 SPG21; maspardin
K06564 IGF2R; insulin-like growth factor 2 receptor
K17917 SNX1_2; sorting nexin-1/2
K17917 SNX1_2; sorting nexin-1/2
K17920 SNX5_6_32; sorting nexin-5/6/32
K17920 SNX5_6_32; sorting nexin-5/6/32
K17920 SNX5_6_32; sorting nexin-5/6/32
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K02833 HRAS; GTPase HRas
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04513 RHOA; Ras homolog gene family, member A
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K13649 FOLR; folate receptor
K13649 FOLR; folate receptor
K13649 FOLR; folate receptor
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K12476 EHD3; EH domain-containing protein 3
K12477 EHD4; EH domain-containing protein 4
K12478 EEA1; early endosome antigen 1
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K12480 RABEP1; Rab GTPase-binding effector protein 1
K12481 RBSN; rabenosyn-5
K07879 RAB4A; Ras-related protein Rab-4A
K12482 RUFY1_2; RUN and FYVE domain-containing protein 1/2
K12482 RUFY1_2; RUN and FYVE domain-containing protein 1/2
K12483 EHD1; EH domain-containing protein 1
K12479 VPS45; vacuolar protein sorting-associated protein 45
K17919 SNX4; sorting nexin-4
K07891 RAB22; Ras-related protein Rab-22
K07891 RAB22; Ras-related protein Rab-22
K07903 RAB10; Ras-related protein Rab-10
K07901 RAB8A; Ras-related protein Rab-8A
K07876 RAB35; Ras-related protein Rab-35
K07904 RAB11A; Ras-related protein Rab-11A
K07905 RAB11B; Ras-related protein Rab-11B
K12484 RAB11FIP1_2_5; Rab11 family-interacting protein 1/2/5
K12484 RAB11FIP1_2_5; Rab11 family-interacting protein 1/2/5
K12484 RAB11FIP1_2_5; Rab11 family-interacting protein 1/2/5
K19368 ZFYVE27; protrudin
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K12485 RAB11FIP3_4; Rab11 family-interacting protein 3/4
K12485 RAB11FIP3_4; Rab11 family-interacting protein 3/4
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K04393 CDC42; cell division control protein 42
K12486 SMAP; stromal membrane-associated protein
K12486 SMAP; stromal membrane-associated protein
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K12487 GIT2; G protein-coupled receptor kinase interactor 2
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
K18439 ARAP1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
K18440 ARAP2; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K12491 AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
K12491 AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
K12491 AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
K12491 AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
K12491 AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
K12491 AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
K12494 PSD; PH and SEC7 domain-containing protein
K12494 PSD; PH and SEC7 domain-containing protein
K12494 PSD; PH and SEC7 domain-containing protein
K12494 PSD; PH and SEC7 domain-containing protein
K12495 IQSEC; IQ motif and SEC7 domain-containing protein
K12495 IQSEC; IQ motif and SEC7 domain-containing protein
K12495 IQSEC; IQ motif and SEC7 domain-containing protein
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
K07937 ARF1_2; ADP-ribosylation factor 1/2
K07938 ARF3; ADP-ribosylation factor 3
K07939 ARF4; ADP-ribosylation factor 4
K07940 ARF5; ADP-ribosylation factor 5
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04145 Phagosome [PATH:hsa04145]
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04142 Lysosome [PATH:hsa04142]
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04146 Peroxisome [PATH:hsa04146]
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04140 Autophagy - animal [PATH:hsa04140]
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04138 Autophagy - yeast
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04136 Autophagy - other [PATH:hsa04136]
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04137 Mitophagy - animal [PATH:hsa04137]
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04139 Mitophagy - yeast
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04148 Efferocytosis [PATH:hsa04148]
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|
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09143 Cell growth and death
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04110 Cell cycle [PATH:hsa04110]
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595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
5933 RBL1; RB transcriptional corepressor like 1
5934 RBL2; RB transcriptional corepressor like 2
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
1874 E2F4; E2F transcription factor 4
1875 E2F5; E2F transcription factor 5
7027 TFDP1; transcription factor Dp-1
7029 TFDP2; transcription factor Dp-2
2932 GSK3B; glycogen synthase kinase 3 beta
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
4609 MYC; MYC proto-oncogene, bHLH transcription factor
7709 ZBTB17; zinc finger and BTB domain containing 17
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1031 CDKN2C; cyclin dependent kinase inhibitor 2C
1032 CDKN2D; cyclin dependent kinase inhibitor 2D
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1028 CDKN1C; cyclin dependent kinase inhibitor 1C
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
1017 CDK2; cyclin dependent kinase 2
6500 SKP1; S-phase kinase associated protein 1
8454 CUL1; cullin 1
9978 RBX1; ring-box 1
6502 SKP2; S-phase kinase associated protein 2
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
990 CDC6; cell division cycle 6
81620 CDT1; chromatin licensing and DNA replication factor 1
4998 ORC1; origin recognition complex subunit 1
4999 ORC2; origin recognition complex subunit 2
23595 ORC3; origin recognition complex subunit 3
5000 ORC4; origin recognition complex subunit 4
5001 ORC5; origin recognition complex subunit 5
23594 ORC6; origin recognition complex subunit 6
4171 MCM2; minichromosome maintenance complex component 2
4172 MCM3; minichromosome maintenance complex component 3
4173 MCM4; minichromosome maintenance complex component 4
4174 MCM5; minichromosome maintenance complex component 5
4175 MCM6; minichromosome maintenance complex component 6
4176 MCM7; minichromosome maintenance complex component 7
8318 CDC45; cell division cycle 45
90381 TICRR; TOPBP1 interacting checkpoint and replication regulator
27085 MTBP; MDM2 binding protein
8317 CDC7; cell division cycle 7
10926 DBF4; DBF4-CDC7 kinase regulatory subunit
80174 DBF4B; DBF4B-CDC7 kinase regulatory subunit
983 CDK1; cyclin dependent kinase 1
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
85417 CCNB3; cyclin B3
994 CDC25B; cell division cycle 25B
995 CDC25C; cell division cycle 25C
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
5347 PLK1; polo like kinase 1
7465 WEE1; WEE1 G2 checkpoint kinase
494551 WEE2; WEE2 oocyte meiosis inhibiting kinase
9088 PKMYT1; protein kinase, membrane associated tyrosine/threonine 1
902 CCNH; cyclin H
1022 CDK7; cyclin dependent kinase 7
64682 ANAPC1; anaphase promoting complex subunit 1
29882 ANAPC2; anaphase promoting complex subunit 2
996 CDC27; cell division cycle 27
29945 ANAPC4; anaphase promoting complex subunit 4
51433 ANAPC5; anaphase promoting complex subunit 5
8881 CDC16; cell division cycle 16
51434 ANAPC7; anaphase promoting complex subunit 7
8697 CDC23; cell division cycle 23
10393 ANAPC10; anaphase promoting complex subunit 10
51529 ANAPC11; anaphase promoting complex subunit 11
246184 CDC26; cell division cycle 26
25847 ANAPC13; anaphase promoting complex subunit 13
25906 ANAPC15; anaphase promoting complex subunit 15
119504 ANAPC16; anaphase promoting complex subunit 16
991 CDC20; cell division cycle 20
9232 PTTG1; PTTG1 regulator of sister chromatid separation, securin
10744 PTTG2; pituitary tumor-transforming 2
9700 ESPL1; extra spindle pole bodies like 1, separase
8243 SMC1A; structural maintenance of chromosomes 1A
27127 SMC1B; structural maintenance of chromosomes 1B
9126 SMC3; structural maintenance of chromosomes 3
5885 RAD21; RAD21 cohesin complex component
10735 STAG2; STAG2 cohesin complex component
10274 STAG1; STAG1 cohesin complex component
546 ATRX; ATRX chromatin remodeler
1663 DDX11; DEAD/H-box helicase 11
25836 NIPBL; NIPBL cohesin loading factor
23383 MAU2; MAU2 sister chromatid cohesion factor
55869 HDAC8; histone deacetylase 8
114799 ESCO1; establishment of sister chromatid cohesion N-acetyltransferase 1
157570 ESCO2; establishment of sister chromatid cohesion N-acetyltransferase 2
23244 PDS5A; PDS5 cohesin associated factor A
23047 PDS5B; PDS5 cohesin associated factor B
23063 WAPL; WAPL cohesin release factor
113130 CDCA5; cell division cycle associated 5
9212 AURKB; aurora kinase B
151648 SGO1; shugoshin 1
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
10403 NDC80; NDC80 kinetochore complex component
57082 KNL1; kinetochore scaffold 1
7272 TTK; TTK protein kinase
8379 MAD1L1; mitotic arrest deficient 1 like 1
4085 MAD2L1; mitotic arrest deficient 2 like 1
10459 MAD2L2; mitotic arrest deficient 2 like 2
701 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
9184 BUB3; BUB3 mitotic checkpoint protein
699 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
9319 TRIP13; thyroid hormone receptor interactor 13
9587 MAD2L1BP; MAD2L1 binding protein
51343 FZR1; fizzy and cell division cycle 20 related 1
26271 FBXO5; F-box protein 5
8555 CDC14B; cell division cycle 14B
8556 CDC14A; cell division cycle 14A
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
5591 PRKDC; protein kinase, DNA-activated, catalytic subunit
545 ATR; ATR serine/threonine kinase
472 ATM; ATM serine/threonine kinase
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
5111 PCNA; proliferating cell nuclear antigen
2810 SFN; stratifin
1111 CHEK1; checkpoint kinase 1
11200 CHEK2; checkpoint kinase 2
993 CDC25A; cell division cycle 25A
|
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K09993 CDKN1C; cyclin-dependent kinase inhibitor 1C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K10727 CDT1; chromatin licensing and DNA replication factor 1
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
K06628 CDC45; cell division control protein 45
K26117 TICRR; Treslin
K26116 MTBP; Mdm2-binding protein
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 DBF4; protein DBF4
K06629 DBF4; protein DBF4
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K25228 APC15; anaphase-promoting complex subunit 15
K25229 APC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06670 SCC1; cohesin complex subunit SCC1
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K10779 ATRX; transcriptional regulator ATRX
K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
K06672 SCC2; cohesin loading factor subunit SCC2
K11266 MAU2; MAternally affected uncoordination
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
K11267 PDS5; sister chromatid cohesion protein PDS5
K11267 PDS5; sister chromatid cohesion protein PDS5
K25163 WAPL; wings apart-like protein
K17390 CDCA5; sororin
K11479 AURKB; aurora kinase B [EC:2.7.11.1]
K11580 SGOL1; shugoshin-like 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11547 NDC80; kinetochore protein NDC80
K11542 CASC5; protein CASC5
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K22399 TRIP13; pachytene checkpoint protein 2
K26093 MAD2L1BP; MAD2L1-binding protein
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K10292 FBXO5; F-box protein 5
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K06644 SFN; stratifin
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
|
04111 Cell cycle - yeast
|
04112 Cell cycle - Caulobacter
|
04113 Meiosis - yeast
|
04114 Oocyte meiosis [PATH:hsa04114]
|
04210 Apoptosis [PATH:hsa04210]
|
04214 Apoptosis - fly
|
04215 Apoptosis - multiple species [PATH:hsa04215]
|
04216 Ferroptosis [PATH:hsa04216]
|
04217 Necroptosis [PATH:hsa04217]
|
04115 p53 signaling pathway [PATH:hsa04115]
|
04218 Cellular senescence [PATH:hsa04218]
|
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
5925 RB1; RB transcriptional corepressor 1
5933 RBL1; RB transcriptional corepressor like 1
5934 RBL2; RB transcriptional corepressor like 2
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
1874 E2F4; E2F transcription factor 4
1875 E2F5; E2F transcription factor 5
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
2308 FOXO1; forkhead box O1
2309 FOXO3; forkhead box O3
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
3105 HLA-A; major histocompatibility complex, class I, A
3106 HLA-B; major histocompatibility complex, class I, B
3107 HLA-C; major histocompatibility complex, class I, C
3134 HLA-F; major histocompatibility complex, class I, F
3135 HLA-G; major histocompatibility complex, class I, G
3133 HLA-E; major histocompatibility complex, class I, E
3805 KIR2DL4; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
3265 HRAS; HRas proto-oncogene, GTPase
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
7248 TSC1; TSC complex subunit 1
7249 TSC2; TSC complex subunit 2
6009 RHEB; Ras homolog, mTORC1 binding
2475 MTOR; mechanistic target of rapamycin kinase
5728 PTEN; phosphatase and tensin homolog
23411 SIRT1; sirtuin 1
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
4605 MYBL2; MYB proto-oncogene like 2
286826 LIN9; lin-9 DREAM MuvB core complex component
55957 LIN37; lin-37 DREAM MuvB core complex component
91750 LIN52; lin-52 DREAM MuvB core complex component
132660 LIN54; lin-54 DREAM MuvB core complex component
5928 RBBP4; RB binding protein 4, chromatin remodeling factor
2305 FOXM1; forkhead box M1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
83593 RASSF5; Ras association domain family member 5
8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
23291 FBXW11; F-box and WD repeat domain containing 11
10114 HIPK3; homeodomain interacting protein kinase 3
204851 HIPK1; homeodomain interacting protein kinase 1
28996 HIPK2; homeodomain interacting protein kinase 2
147746 HIPK4; homeodomain interacting protein kinase 4
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2113 ETS1; ETS proto-oncogene 1, transcription factor
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
983 CDK1; cyclin dependent kinase 1
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
85417 CCNB3; cyclin B3
4361 MRE11; MRE11 homolog, double strand break repair nuclease
10111 RAD50; RAD50 double strand break repair protein
4683 NBN; nibrin
472 ATM; ATM serine/threonine kinase
11200 CHEK2; checkpoint kinase 2
5883 RAD9A; RAD9 checkpoint clamp component A
144715 RAD9B; RAD9 checkpoint clamp component B
5810 RAD1; RAD1 checkpoint DNA exonuclease
3364 HUS1; HUS1 checkpoint clamp component
545 ATR; ATR serine/threonine kinase
1111 CHEK1; checkpoint kinase 1
993 CDC25A; cell division cycle 25A
8878 SQSTM1; sequestosome 1
2626 GATA4; GATA binding protein 4
10758 TRAF3IP2; TRAF3 interacting protein 2
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
3552 IL1A; interleukin 1 alpha
3569 IL6; interleukin 6
3576 CXCL8; C-X-C motif chemokine ligand 8
3486 IGFBP3; insulin like growth factor binding protein 3
5054 SERPINE1; serpin family E member 1
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
9261 MAPKAPK2; MAPK activated protein kinase 2
677 ZFP36L1; ZFP36 ring finger protein like 1
678 ZFP36L2; ZFP36 ring finger protein like 2
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
59341 TRPV4; transient receptor potential cation channel subfamily V member 4
54822 TRPM7; transient receptor potential cation channel subfamily M member 7
823 CAPN1; calpain 1
824 CAPN2; calpain 2
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
4776 NFATC4; nuclear factor of activated T cells 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
5481 PPID; peptidylprolyl isomerase D
7416 VDAC1; voltage dependent anion channel 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
90550 MCU; mitochondrial calcium uniporter
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K24231 KIR2DL4; killer cell immunoglobulin-like receptor 2DL4
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21769 MYBL2; myb-related protein B
K21773 LIN9; protein lin-9
K21774 LIN37; protein lin-37
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04383 IL1A; interleukin 1 alpha
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1; plasminogen activator inhibitor 1
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
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09144 Cellular community - eukaryotes
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04510 Focal adhesion [PATH:hsa04510]
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04520 Adherens junction [PATH:hsa04520]
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04530 Tight junction [PATH:hsa04530]
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04540 Gap junction [PATH:hsa04540]
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04550 Signaling pathways regulating pluripotency of stem cells [PATH:hsa04550]
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3976 LIF; LIF interleukin 6 family cytokine
3977 LIFR; LIF receptor subunit alpha
3572 IL6ST; interleukin 6 cytokine family signal transducer
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
6774 STAT3; signal transducer and activator of transcription 3
9314 KLF4; KLF transcription factor 4
6657 SOX2; SRY-box transcription factor 2
4609 MYC; MYC proto-oncogene, bHLH transcription factor
2885 GRB2; growth factor receptor bound protein 2
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
6926 TBX3; T-box transcription factor 3
79923 NANOG; Nanog homeobox
388112 NANOGP8; Nanog homeobox retrogene P8
3624 INHBA; inhibin subunit beta A
3625 INHBB; inhibin subunit beta B
3626 INHBC; inhibin subunit beta C
83729 INHBE; inhibin subunit beta E
4838 NODAL; nodal growth differentiation factor
91 ACVR1B; activin A receptor type 1B
130399 ACVR1C; activin A receptor type 1C
92 ACVR2A; activin A receptor type 2A
93 ACVR2B; activin A receptor type 2B
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
652 BMP4; bone morphogenetic protein 4
657 BMPR1A; bone morphogenetic protein receptor type 1A
658 BMPR1B; bone morphogenetic protein receptor type 1B
90 ACVR1; activin A receptor type 1
659 BMPR2; bone morphogenetic protein receptor type 2
4086 SMAD1; SMAD family member 1
4090 SMAD5; SMAD family member 5
4093 SMAD9; SMAD family member 9
4089 SMAD4; SMAD family member 4
3397 ID1; inhibitor of DNA binding 1
3398 ID2; inhibitor of DNA binding 2
3399 ID3; inhibitor of DNA binding 3
3400 ID4; inhibitor of DNA binding 4
1852 DUSP9; dual specificity phosphatase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
6929 TCF3; transcription factor 3
2103 ESRRB; estrogen related receptor beta
6932 TCF7; transcription factor 7
5460 POU5F1; POU class 5 homeobox 1
5462 POU5F1B; POU class 5 homeobox 1B
2247 FGF2; fibroblast growth factor 2
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
8820 HESX1; HESX homeobox 1
7547 ZIC3; Zic family member 3
10637 LEFTY1; left-right determination factor 1
7044 LEFTY2; left-right determination factor 2
6498 SKIL; SKI like proto-oncogene
56916 SMARCAD1; SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
7994 KAT6A; lysine acetyltransferase 6A
9869 SETDB1; SET domain bifurcated histone lysine methyltransferase 1
3720 JARID2; jumonji and AT-rich interaction domain containing 2
5978 REST; RE1 silencing transcription factor
55183 RIF1; replication timing regulatory factor 1
84759 PCGF1; polycomb group ring finger 1
7703 PCGF2; polycomb group ring finger 2
10336 PCGF3; polycomb group ring finger 3
648 BMI1; BMI1 proto-oncogene, polycomb ring finger
100532731 COMMD3-BMI1; COMMD3-BMI1 readthrough
84333 PCGF5; polycomb group ring finger 5
84108 PCGF6; polycomb group ring finger 6
5080 PAX6; paired box 6
4211 MEIS1; Meis homeobox 1
3211 HOXB1; homeobox B1
3198 HOXA1; homeobox A1
3231 HOXD1; homeobox D1
64211 LHX5; LIM homeobox 5
5013 OTX1; orthodenticle homeobox 1
4762 NEUROG1; neurogenin 1
9421 HAND1; heart and neural crest derivatives expressed 1
1749 DLX5; distal-less homeobox 5
4617 MYF5; myogenic factor 5
3175 ONECUT1; one cut homeobox 1
3670 ISL1; ISL LIM homeobox 1
463 ZFHX3; zinc finger homeobox 3
80712 ESX1; ESX homeobox 1
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K05419 LIF; leukemia inhibitory factor
K05058 LIFR; leukemia inhibitory factor receptor
K05060 IL6ST; interleukin 6 signal transducer
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K17846 KLF4; krueppel-like factor 4
K16796 SOX2; transcription factor SOX2 (SOX group B)
K04377 MYC; Myc proto-oncogene protein
K04364 GRB2; growth factor receptor-bound protein 2
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K10177 TBX3; T-box protein 3
K10164 NANOG; homeobox protein Nanog
K10164 NANOG; homeobox protein Nanog
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04666 NODAL; nodal
K13567 ACVR1B; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C; activin receptor type-1C [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04662 BMP4; bone morphogenetic protein 4
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K16790 SMAD5; mothers against decapentaplegic homolog 5
K16791 SMAD9; mothers against decapentaplegic homolog 9
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K17694 ID3; DNA-binding protein inhibitor ID3
K17695 ID4; DNA-binding protein inhibitor ID4
K18498 DUSP9; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K09063 TCF3; transcription factor E2-alpha
K08553 NR3B2; estrogen-related receptor beta
K02620 TCF7; transcription factor 7
K09367 POU5F; POU domain transcription factor, class 5
K09367 POU5F; POU domain transcription factor, class 5
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K09354 HESX1; homeobox protein expressed in ES cells 1
K18487 ZIC3; zinc finger protein ZIC 3
K04668 LEFTY; left-right determination factor
K04668 LEFTY; left-right determination factor
K18499 SKIL; Ski-like protein
K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
K11305 MYST3; histone acetyltransferase MYST3 [EC:2.3.1.48]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K11478 JARID2; protein Jumonji
K09222 REST; RE1-silencing transcription factor
K11138 RIF1; telomere-associated protein RIF1
K11487 PCGF1; polycomb group RING finger protein 1
K11460 PCGF2; polycomb group RING finger protein 2
K11488 PCGF3; polycomb group RING finger protein 3
K11459 PCGF4; polycomb group RING finger protein 4
K11459 PCGF4; polycomb group RING finger protein 4
K11489 PCGF5; polycomb group RING finger protein 5
K11470 PCGF6; polycomb group RING finger protein 6
K08031 PAX6; paired box protein 6
K15613 MEIS1; homeobox protein Meis1
K09301 HOX_1; homeobox protein HoxA/B/D1
K09301 HOX_1; homeobox protein HoxA/B/D1
K09301 HOX_1; homeobox protein HoxA/B/D1
K18493 LHX5; LIM homeobox protein 5
K09326 OTX1; homeobox protein OTX1
K09081 NEUROG1; neurogenin 1
K09071 HAND1; heart-and neural crest derivatives-expressed protein 1
K18489 DLX5; homeobox protein DLX5
K18484 MYF5; myogenic factor 5
K08026 ONECUT1; one cut domain, family member 1 (hepatocyte nuclear factor 6)
K09370 ISL1; insulin gene enhancer protein ISL-1
K09378 ZFHX3; zinc finger homeobox protein 3
K18491 ESX1; homeobox protein ESX1
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09145 Cellular community - prokaryotes
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09142 Cell motility
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09150 Organismal Systems
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09151 Immune system
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04640 Hematopoietic cell lineage [PATH:hsa04640]
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04610 Complement and coagulation cascades [PATH:hsa04610]
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04611 Platelet activation [PATH:hsa04611]
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04613 Neutrophil extracellular trap formation [PATH:hsa04613]
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04620 Toll-like receptor signaling pathway [PATH:hsa04620]
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04624 Toll and Imd signaling pathway
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04621 NOD-like receptor signaling pathway [PATH:hsa04621]
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04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
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04623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
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04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
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04650 Natural killer cell mediated cytotoxicity [PATH:hsa04650]
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04612 Antigen processing and presentation [PATH:hsa04612]
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04660 T cell receptor signaling pathway [PATH:hsa04660]
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04658 Th1 and Th2 cell differentiation [PATH:hsa04658]
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04659 Th17 cell differentiation [PATH:hsa04659]
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3553 IL1B; interleukin 1 beta
3554 IL1R1; interleukin 1 receptor type 1
3556 IL1RAP; interleukin 1 receptor accessory protein
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
2475 MTOR; mechanistic target of rapamycin kinase
3662 IRF4; interferon regulatory factor 4
7040 TGFB1; transforming growth factor beta 1
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
59067 IL21; interleukin 21
50615 IL21R; interleukin 21 receptor
3561 IL2RG; interleukin 2 receptor subunit gamma
3716 JAK1; Janus kinase 1
3718 JAK3; Janus kinase 3
3569 IL6; interleukin 6
3570 IL6R; interleukin 6 receptor
3572 IL6ST; interleukin 6 cytokine family signal transducer
3717 JAK2; Janus kinase 2
51561 IL23A; interleukin 23 subunit alpha
149233 IL23R; interleukin 23 receptor
3594 IL12RB1; interleukin 12 receptor subunit beta 1
7297 TYK2; tyrosine kinase 2
6774 STAT3; signal transducer and activator of transcription 3
6097 RORC; RAR related orphan receptor C
6095 RORA; RAR related orphan receptor A
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
196 AHR; aryl hydrocarbon receptor
3605 IL17A; interleukin 17A
112744 IL17F; interleukin 17F
50616 IL22; interleukin 22
3108 HLA-DMA; major histocompatibility complex, class II, DM alpha
3109 HLA-DMB; major histocompatibility complex, class II, DM beta
3111 HLA-DOA; major histocompatibility complex, class II, DO alpha
3112 HLA-DOB; major histocompatibility complex, class II, DO beta
3113 HLA-DPA1; major histocompatibility complex, class II, DP alpha 1
3115 HLA-DPB1; major histocompatibility complex, class II, DP beta 1
3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1
3118 HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2
3119 HLA-DQB1; major histocompatibility complex, class II, DQ beta 1
3122 HLA-DRA; major histocompatibility complex, class II, DR alpha
3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1
3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3
3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4
3127 HLA-DRB5; major histocompatibility complex, class II, DR beta 5
920 CD4; CD4 molecule
3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
916 CD3E; CD3 epsilon subunit of T-cell receptor complex
917 CD3G; CD3 gamma subunit of T-cell receptor complex
919 CD247; CD247 molecule
915 CD3D; CD3 delta subunit of T-cell receptor complex
7535 ZAP70; zeta chain of T cell receptor associated protein kinase 70
27040 LAT; linker for activation of T cells
5335 PLCG1; phospholipase C gamma 1
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
5588 PRKCQ; protein kinase C theta
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4793 NFKBIB; NFKB inhibitor beta
4794 NFKBIE; NFKB inhibitor epsilon
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
3565 IL4; interleukin 4
3566 IL4R; interleukin 4 receptor
6778 STAT6; signal transducer and activator of transcription 6
2625 GATA3; GATA binding protein 3
861 RUNX1; RUNX family transcription factor 1
246778 IL27; interleukin 27
10148 EBI3; Epstein-Barr virus induced 3
9466 IL27RA; interleukin 27 receptor subunit alpha
3458 IFNG; interferon gamma
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
6772 STAT1; signal transducer and activator of transcription 1
30009 TBX21; T-box transcription factor 21
3558 IL2; interleukin 2
3559 IL2RA; interleukin 2 receptor subunit alpha
3560 IL2RB; interleukin 2 receptor subunit beta
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
50943 FOXP3; forkhead box P3
5914 RARA; retinoic acid receptor alpha
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
|
K04519 IL1B; interleukin 1 beta
K04386 IL1R1; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K09445 IRF4; interferon regulatory factor 4
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K05434 IL21; interleukin 21
K05075 IL21R; interleukin 21 receptor
K05070 IL2RG; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K05405 IL6; interleukin 6
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K05426 IL23A; interleukin 23 subunit alpha
K05065 IL23R; interleukin 23 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K08534 NR1F3; RAR-related orphan receptor gamma
K08532 NR1F1; RAR-related orphan receptor alpha
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09093 AHR; aryl hydrocarbon receptor
K05489 IL17A; interleukin 17A
K05494 IL17F; interleukin 17F
K05445 IL22; interleukin 22
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05430 IL4; interleukin 4
K05071 IL4R; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K08367 RUNX1; runt-related transcription factor 1
K22629 IL27; interleukin 27 subunit alpha
K24476 EBI3; interleukin 27 subunit beta
K19598 IL27RA; interleukin 27 receptor alpha
K04687 IFNG; interferon gamma
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K10166 TBX21; T-box protein 21
K05429 IL2; interleukin 2
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K10163 FOXP3; forkhead box P3
K08527 RARA; retinoic acid receptor alpha
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
|
04657 IL-17 signaling pathway [PATH:hsa04657]
|
04662 B cell receptor signaling pathway [PATH:hsa04662]
|
04664 Fc epsilon RI signaling pathway [PATH:hsa04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:hsa04666]
|
04670 Leukocyte transendothelial migration [PATH:hsa04670]
|
04672 Intestinal immune network for IgA production [PATH:hsa04672]
|
04062 Chemokine signaling pathway [PATH:hsa04062]
|
|
|
09152 Endocrine system
|
04911 Insulin secretion [PATH:hsa04911]
|
04910 Insulin signaling pathway [PATH:hsa04910]
|
04922 Glucagon signaling pathway [PATH:hsa04922]
|
04923 Regulation of lipolysis in adipocytes [PATH:hsa04923]
|
04920 Adipocytokine signaling pathway [PATH:hsa04920]
|
03320 PPAR signaling pathway [PATH:hsa03320]
|
04929 GnRH secretion [PATH:hsa04929]
|
04912 GnRH signaling pathway [PATH:hsa04912]
|
04913 Ovarian steroidogenesis [PATH:hsa04913]
|
04915 Estrogen signaling pathway [PATH:hsa04915]
|
04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
|
04917 Prolactin signaling pathway [PATH:hsa04917]
|
04921 Oxytocin signaling pathway [PATH:hsa04921]
|
04926 Relaxin signaling pathway [PATH:hsa04926]
|
6013 RLN1; relaxin 1
6019 RLN2; relaxin 2
59350 RXFP1; relaxin family peptide receptor 1
2775 GNAO1; G protein subunit alpha o1
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2778 GNAS; GNAS complex locus
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
111 ADCY5; adenylate cyclase 5
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
4843 NOS2; nitric oxide synthase 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5590 PRKCZ; protein kinase C zeta
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
4846 NOS3; nitric oxide synthase 3
4842 NOS1; nitric oxide synthase 1
1906 EDN1; endothelin 1
1910 EDNRB; endothelin receptor type B
4312 MMP1; matrix metallopeptidase 1
4322 MMP13; matrix metallopeptidase 13
7040 TGFB1; transforming growth factor beta 1
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
59 ACTA2; actin alpha 2, smooth muscle
1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
1281 COL3A1; collagen type III alpha 1 chain
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
3640 INSL3; insulin like 3
122042 RXFP2; relaxin family peptide receptor 2
117579 RLN3; relaxin 3
51289 RXFP3; relaxin family peptide receptor 3
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5578 PRKCA; protein kinase C alpha
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
408 ARRB1; arrestin beta 1
409 ARRB2; arrestin beta 2
1956 EGFR; epidermal growth factor receptor
2885 GRB2; growth factor receptor bound protein 2
10022 INSL5; insulin like 5
339403 RXFP4; relaxin family peptide/INSL5 receptor 4
2769 GNA15; G protein subunit alpha 15
|
K21998 RLN1_2; relaxin 1/2
K21998 RLN1_2; relaxin 1/2
K04306 RXFP1; relaxin family peptide receptor 1
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K16366 EDN1; endothelin-1
K04198 EDNRB; endothelin receptor type B
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K12313 ACTA2; actin, aortic smooth muscle
K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K21999 INSL3; insulin-like 3
K04307 RXFP2; relaxin family peptide receptor 2
K22000 RLN3; relaxin 3
K08397 RXFP3; relaxin family peptide receptor 3
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K22001 INSL5; insulin-like 5
K08398 RXFP4; relaxin family peptide receptor 4
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
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04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
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04918 Thyroid hormone synthesis [PATH:hsa04918]
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04919 Thyroid hormone signaling pathway [PATH:hsa04919]
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04928 Parathyroid hormone synthesis, secretion and action [PATH:hsa04928]
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04916 Melanogenesis [PATH:hsa04916]
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04924 Renin secretion [PATH:hsa04924]
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04614 Renin-angiotensin system [PATH:hsa04614]
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04925 Aldosterone synthesis and secretion [PATH:hsa04925]
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04927 Cortisol synthesis and secretion [PATH:hsa04927]
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:hsa05200]
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1630 DCC; DCC netrin 1 receptor
836 CASP3; caspase 3
842 CASP9; caspase 9
26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
999 CDH1; cadherin 1
1499 CTNNB1; catenin beta 1
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
332 BIRC5; baculoviral IAP repeat containing 5
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2147 F2; coagulation factor II, thrombin
183 AGT; angiotensinogen
2149 F2R; coagulation factor II thrombin receptor
9002 F2RL3; F2R like thrombin or trypsin receptor 3
1902 LPAR1; lysophosphatidic acid receptor 1
9170 LPAR2; lysophosphatidic acid receptor 2
23566 LPAR3; lysophosphatidic acid receptor 3
2846 LPAR4; lysophosphatidic acid receptor 4
57121 LPAR5; lysophosphatidic acid receptor 5
10161 LPAR6; lysophosphatidic acid receptor 6
185 AGTR1; angiotensin II receptor type 1
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
57449 PLEKHG5; pleckstrin homology and RhoGEF domain containing G5
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
6387 CXCL12; C-X-C motif chemokine ligand 12
7852 CXCR4; C-X-C motif chemokine receptor 4
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
5731 PTGER1; prostaglandin E receptor 1
5732 PTGER2; prostaglandin E receptor 2
5733 PTGER3; prostaglandin E receptor 3
5734 PTGER4; prostaglandin E receptor 4
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
284217 LAMA1; laminin subunit alpha 1
3908 LAMA2; laminin subunit alpha 2
3909 LAMA3; laminin subunit alpha 3
3911 LAMA5; laminin subunit alpha 5
3910 LAMA4; laminin subunit alpha 4
3912 LAMB1; laminin subunit beta 1
3913 LAMB2; laminin subunit beta 2
3914 LAMB3; laminin subunit beta 3
22798 LAMB4; laminin subunit beta 4
3915 LAMC1; laminin subunit gamma 1
3918 LAMC2; laminin subunit gamma 2
10319 LAMC3; laminin subunit gamma 3
2335 FN1; fibronectin 1
3673 ITGA2; integrin subunit alpha 2
3674 ITGA2B; integrin subunit alpha 2b
3675 ITGA3; integrin subunit alpha 3
3655 ITGA6; integrin subunit alpha 6
3685 ITGAV; integrin subunit alpha V
3688 ITGB1; integrin subunit beta 1
5747 PTK2; protein tyrosine kinase 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
4824 NKX3-1; NK3 homeobox 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
4791 NFKB2; nuclear factor kappa B subunit 2
5970 RELA; RELA proto-oncogene, NF-kB subunit
5743 PTGS2; prostaglandin-endoperoxide synthase 2
4843 NOS2; nitric oxide synthase 2
596 BCL2; BCL2 apoptosis regulator
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
331 XIAP; X-linked inhibitor of apoptosis
79444 BIRC7; baculoviral IAP repeat containing 7
598 BCL2L1; BCL2 like 1
7185 TRAF1; TNF receptor associated factor 1
7186 TRAF2; TNF receptor associated factor 2
7187 TRAF3; TNF receptor associated factor 3
9618 TRAF4; TNF receptor associated factor 4
7188 TRAF5; TNF receptor associated factor 5
7189 TRAF6; TNF receptor associated factor 6
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
572 BAD; BCL2 associated agonist of cell death
2308 FOXO1; forkhead box O1
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
613 BCR; BCR activator of RhoGEF and GTPase
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
867 CBL; Cbl proto-oncogene
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
3827 KNG1; kininogen 1
1906 EDN1; endothelin 1
623 BDKRB1; bradykinin receptor B1
624 BDKRB2; bradykinin receptor B2
1909 EDNRA; endothelin receptor type A
1910 EDNRB; endothelin receptor type B
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
3558 IL2; interleukin 2
3562 IL3; interleukin 3
3565 IL4; interleukin 4
3567 IL5; interleukin 5
3569 IL6; interleukin 6
3574 IL7; interleukin 7
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3596 IL13; interleukin 13
3600 IL15; interleukin 15
51561 IL23A; interleukin 23 subunit alpha
2056 EPO; erythropoietin
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3458 IFNG; interferon gamma
3559 IL2RA; interleukin 2 receptor subunit alpha
3560 IL2RB; interleukin 2 receptor subunit beta
3561 IL2RG; interleukin 2 receptor subunit gamma
3563 IL3RA; interleukin 3 receptor subunit alpha
3566 IL4R; interleukin 4 receptor
1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
3568 IL5RA; interleukin 5 receptor subunit alpha
3570 IL6R; interleukin 6 receptor
3572 IL6ST; interleukin 6 cytokine family signal transducer
3575 IL7R; interleukin 7 receptor
3594 IL12RB1; interleukin 12 receptor subunit beta 1
3595 IL12RB2; interleukin 12 receptor subunit beta 2
3597 IL13RA1; interleukin 13 receptor subunit alpha 1
3601 IL15RA; interleukin 15 receptor subunit alpha
149233 IL23R; interleukin 23 receptor
2057 EPOR; erythropoietin receptor
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
27436 EML4; EMAP like 4
238 ALK; ALK receptor tyrosine kinase
10125 RASGRP1; RAS guanyl releasing protein 1
10235 RASGRP2; RAS guanyl releasing protein 2
25780 RASGRP3; RAS guanyl releasing protein 3
115727 RASGRP4; RAS guanyl releasing protein 4
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
6774 STAT3; signal transducer and activator of transcription 3
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
6775 STAT4; signal transducer and activator of transcription 4
6778 STAT6; signal transducer and activator of transcription 6
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
7039 TGFA; transforming growth factor alpha
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3479 IGF1; insulin like growth factor 1
3481 IGF2; insulin like growth factor 2
3480 IGF1R; insulin like growth factor 1 receptor
4254 KITLG; KIT ligand
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
2322 FLT3; fms related receptor tyrosine kinase 3
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
2113 ETS1; ETS proto-oncogene 1, transcription factor
4312 MMP1; matrix metallopeptidase 1
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
3576 CXCL8; C-X-C motif chemokine ligand 8
1019 CDK4; cyclin dependent kinase 4
9252 RPS6KA5; ribosomal protein S6 kinase A5
5979 RET; ret proto-oncogene
8030 CCDC6; coiled-coil domain containing 6
8031 NCOA4; nuclear receptor coactivator 4
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
7170 TPM3; tropomyosin 3
7175 TPR; translocated promoter region, nuclear basket protein
10342 TFG; trafficking from ER to golgi regulator
11186 RASSF1; Ras association domain family member 1
83593 RASSF5; Ras association domain family member 5
6789 STK4; serine/threonine kinase 4
1612 DAPK1; death associated protein kinase 1
1613 DAPK3; death associated protein kinase 3
23604 DAPK2; death associated protein kinase 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
2002 ELK1; ETS transcription factor ELK1
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
10928 RALBP1; ralA binding protein 1
998 CDC42; cell division cycle 42
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
7849 PAX8; paired box 8
5468 PPARG; peroxisome proliferator activated receptor gamma
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
5915 RARB; retinoic acid receptor beta
2099 ESR1; estrogen receptor 1
2100 ESR2; estrogen receptor 2
8648 NCOA1; nuclear receptor coactivator 1
8202 NCOA3; nuclear receptor coactivator 3
6667 SP1; Sp1 transcription factor
5467 PPARD; peroxisome proliferator activated receptor delta
3728 JUP; junction plakoglobin
7704 ZBTB16; zinc finger and BTB domain containing 16
5914 RARA; retinoic acid receptor alpha
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
5371 PML; PML nuclear body scaffold
861 RUNX1; RUNX family transcription factor 1
862 RUNX1T1; RUNX1 partner transcriptional co-repressor 1
6688 SPI1; Spi-1 proto-oncogene
1050 CEBPA; CCAAT enhancer binding protein alpha
1438 CSF2RA; colony stimulating factor 2 receptor subunit alpha
1441 CSF3R; colony stimulating factor 3 receptor
1436 CSF1R; colony stimulating factor 1 receptor
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
4149 MAX; MYC associated factor X
7709 ZBTB17; zinc finger and BTB domain containing 17
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1021 CDK6; cyclin dependent kinase 6
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1163 CKS1B; CDC28 protein kinase regulatory subunit 1B
1164 CKS2; CDC28 protein kinase regulatory subunit 2
6500 SKP1; S-phase kinase associated protein 1
8454 CUL1; cullin 1
9978 RBX1; ring-box 1
6502 SKP2; S-phase kinase associated protein 2
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
4286 MITF; melanocyte inducing transcription factor
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
2122 MECOM; MDS1 and EVI1 complex locus
1487 CTBP1; C-terminal binding protein 1
1488 CTBP2; C-terminal binding protein 2
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
4292 MLH1; mutL homolog 1
4436 MSH2; mutS homolog 2
4437 MSH3; mutS homolog 3
2956 MSH6; mutS homolog 6
675 BRCA2; BRCA2 DNA repair associated
5888 RAD51; RAD51 recombinase
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
637 BID; BH3 interacting domain death agonist
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
27113 BBC3; BCL2 binding component 3
10018 BCL2L11; BCL2 like 11
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
840 CASP7; caspase 7
9817 KEAP1; kelch like ECH associated protein 1
4780 NFE2L2; NFE2 like bZIP transcription factor 2
3162 HMOX1; heme oxygenase 1
1728 NQO1; NAD(P)H quinone dehydrogenase 1
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
2950 GSTP1; glutathione S-transferase pi 1
7296 TXNRD1; thioredoxin reductase 1
114112 TXNRD3; thioredoxin reductase 3
10587 TXNRD2; thioredoxin reductase 2
7428 VHL; von Hippel-Lindau tumor suppressor
6921 ELOC; elongin C
6923 ELOB; elongin B
8453 CUL2; cullin 2
54583 EGLN1; egl-9 family hypoxia inducible factor 1
112399 EGLN3; egl-9 family hypoxia inducible factor 3
112398 EGLN2; egl-9 family hypoxia inducible factor 2
2271 FH; fumarate hydratase
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
2034 EPAS1; endothelial PAS domain protein 1
405 ARNT; aryl hydrocarbon receptor nuclear translocator
9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
6513 SLC2A1; solute carrier family 2 member 1
182 JAG1; jagged canonical Notch ligand 1
3714 JAG2; jagged canonical Notch ligand 2
10683 DLL3; delta like canonical Notch ligand 3
28514 DLL1; delta like canonical Notch ligand 1
54567 DLL4; delta like canonical Notch ligand 4
4851 NOTCH1; notch receptor 1
4853 NOTCH2; notch receptor 2
4854 NOTCH3; notch receptor 3
4855 NOTCH4; notch receptor 4
3280 HES1; hes family bHLH transcription factor 1
388585 HES5; hes family bHLH transcription factor 5
26508 HEYL; hes related family bHLH transcription factor with YRPW motif like
23462 HEY1; hes related family bHLH transcription factor with YRPW motif 1
23493 HEY2; hes related family bHLH transcription factor with YRPW motif 2
2324 FLT4; fms related receptor tyrosine kinase 4
6469 SHH; sonic hedgehog signaling molecule
5727 PTCH1; patched 1
6608 SMO; smoothened, frizzled class receptor
374654 KIF7; kinesin family member 7
51684 SUFU; SUFU negative regulator of hedgehog signaling
2735 GLI1; GLI family zinc finger 1
2736 GLI2; GLI family zinc finger 2
2737 GLI3; GLI family zinc finger 3
650 BMP2; bone morphogenetic protein 2
652 BMP4; bone morphogenetic protein 4
64399 HHIP; hedgehog interacting protein
8643 PTCH2; patched 2
367 AR; androgen receptor
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
7184 HSP90B1; heat shock protein 90 beta family member 1
354 KLK3; kallikrein related peptidase 3
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:hsa05202]
|
05206 MicroRNAs in cancer [PATH:hsa05206]
|
05205 Proteoglycans in cancer [PATH:hsa05205]
|
960 CD44; CD44 molecule (IN blood group)
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2017 CTTN; cortactin
3059 HCLS1; hematopoietic cell-specific Lyn substrate 1
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2885 GRB2; growth factor receptor bound protein 2
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5879 RAC1; Rac family small GTPase 1
8826 IQGAP1; IQ motif containing GTPase activating protein 1
998 CDC42; cell division cycle 42
2002 ELK1; ETS transcription factor ELK1
2099 ESR1; estrogen receptor 1
595 CCND1; cyclin D1
71 ACTG1; actin gamma 1
60 ACTB; actin beta
2316 FLNA; filamin A
5058 PAK1; p21 (RAC1) activated kinase 1
7074 TIAM1; TIAM Rac1 associated GEF 1
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
286 ANK1; ankyrin 1
287 ANK2; ankyrin 2
288 ANK3; ankyrin 3
2549 GAB1; GRB2 associated binding protein 1
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
6548 SLC9A1; solute carrier family 9 member A1
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
51196 PLCE1; phospholipase C epsilon 1
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
79923 NANOG; Nanog homeobox
388112 NANOGP8; Nanog homeobox retrogene P8
1655 DDX5; DEAD-box helicase 5
29102 DROSHA; drosha ribonuclease III
6774 STAT3; signal transducer and activator of transcription 3
406991 MIR21; microRNA 21
7291 TWIST1; twist family bHLH transcription factor 1
117581 TWIST2; twist family bHLH transcription factor 2
406902 MIR10A; microRNA 10a
406903 MIR10B; microRNA 10b
3236 HOXD10; homeobox D10
1634 DCN; decorin
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
2475 MTOR; mechanistic target of rapamycin kinase
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1975 EIF4B; eukaryotic translation initiation factor 4B
6194 RPS6; ribosomal protein S6
1956 EGFR; epidermal growth factor receptor
857 CAV1; caveolin 1
858 CAV2; caveolin 2
859 CAV3; caveolin 3
967 CD63; CD63 molecule
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
836 CASP3; caspase 3
7040 TGFB1; transforming growth factor beta 1
7097 TLR2; toll like receptor 2
7099 TLR4; toll like receptor 4
27250 PDCD4; programmed cell death 4
7124 TNF; tumor necrosis factor
3593 IL12B; interleukin 12B
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
2066 ERBB4; erb-b2 receptor tyrosine kinase 4
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1499 CTNNB1; catenin beta 1
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
7023 TFAP4; transcription factor AP-4
7422 VEGFA; vascular endothelial growth factor A
3791 KDR; kinase insert domain receptor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
867 CBL; Cbl proto-oncogene
7078 TIMP3; TIMP metallopeptidase inhibitor 3
7057 THBS1; thrombospondin 1
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
4060 LUM; lumican
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
7042 TGFB2; transforming growth factor beta 2
4087 SMAD2; SMAD family member 2
10855 HPSE; heparanase
60495 HPSE2; heparanase 2 (inactive)
6382 SDC1; syndecan 1
5328 PLAU; plasminogen activator, urokinase
5329 PLAUR; plasminogen activator, urokinase receptor
1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
3673 ITGA2; integrin subunit alpha 2
3688 ITGB1; integrin subunit beta 1
7448 VTN; vitronectin
3685 ITGAV; integrin subunit alpha V
3690 ITGB3; integrin subunit beta 3
2335 FN1; fibronectin 1
3693 ITGB5; integrin subunit beta 5
3082 HGF; hepatocyte growth factor
7471 WNT1; Wnt family member 1
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
3678 ITGA5; integrin subunit alpha 5
6383 SDC2; syndecan 2
7430 EZR; ezrin
5962 RDX; radixin
4478 MSN; moesin
6385 SDC4; syndecan 4
2247 FGF2; fibroblast growth factor 2
2260 FGFR1; fibroblast growth factor receptor 1
10818 FRS2; fibroblast growth factor receptor substrate 2
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
84309 NUDT16L1; nudix hydrolase 16 like 1
5829 PXN; paxillin
5747 PTK2; protein tyrosine kinase 2
1839 HBEGF; heparin binding EGF like growth factor
2817 GPC1; glypican 1
3481 IGF2; insulin like growth factor 2
2719 GPC3; glypican 3
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
6469 SHH; sonic hedgehog signaling molecule
3549 IHH; Indian hedgehog signaling molecule
5727 PTCH1; patched 1
6608 SMO; smoothened, frizzled class receptor
3339 HSPG2; heparan sulfate proteoglycan 2
1514 CTSL; cathepsin L
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
3316 HSPB2; heat shock protein family B (small) member 2
5777 PTPN6; protein tyrosine phosphatase non-receptor type 6
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K06256 CD44; CD44 antigen
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06106 CTTN; cortactin
K06106 CTTN; cortactin
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K04393 CDC42; cell division control protein 42
K04375 ELK1; ETS domain-containing protein Elk-1
K08550 ESR1; estrogen receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04437 FLNA; filamin-A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10380 ANK1; ankyrin-1
K09255 ANK2; ankyrin-2
K09259 ANK3; ankyrin-3
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K10164 NANOG; homeobox protein Nanog
K10164 NANOG; homeobox protein Nanog
K12823 DDX5; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
K03685 rnc; ribonuclease III [EC:3.1.26.3]
K04692 STAT3; signal transducer and activator of transcription 3
K16863 MIR21; microRNA 21
K09069 TWIST; twist
K09069 TWIST; twist
K16864 MIR10A; microRNA 10a
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K04660 DCN; decorin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e; small subunit ribosomal protein S6e
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K06497 CD63; CD63 antigen
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13375 TGFB1; transforming growth factor beta-1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K16865 PDCD4; programmed cell death protein 4
K03156 TNF; tumor necrosis factor superfamily, member 2
K05425 IL12B; interleukin 12B
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04377 MYC; Myc proto-oncogene protein
K02105 CTNNB1; catenin beta 1
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09108 TFAP4; transcription factor AP-4
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K16866 TIMP3; metalloproteinase inhibitor 3
K16857 THBS1; thrombospondin 1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08122 LUM; lumican
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K13376 TGFB2; transforming growth factor beta-2
K04500 SMAD2; mothers against decapentaplegic homolog 2
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K06257 SDC1; syndecan 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03985 PLAUR; plasminogen activator, urokinase receptor
K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K06481 ITGA2; integrin alpha 2
K05719 ITGB1; integrin beta 1
K06251 VTN; vitronectin
K06487 ITGAV; integrin alpha V
K06493 ITGB3; integrin beta 3
K05717 FN1; fibronectin 1
K06588 ITGB5; integrin beta 5
K05460 HGF; hepatocyte growth factor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K06484 ITGA5; integrin alpha 5
K16336 SDC2; syndecan 2
K08007 EZR; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K16338 SDC4; syndecan 4
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K12461 FRS2; fibroblast growth factor receptor substrate 2
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K16867 NUDT16L1; NUDT16-like protein 1
K05760 PXN; paxillin
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08107 GPC1; glypican 1
K13769 IGF2; insulin-like growth factor 2
K08109 GPC3; glypican 3
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K11988 SHH; sonic hedgehog
K11989 IHH; indian hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K09543 HSPB2; heat shock protein beta-2
K05697 PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:hsa05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:hsa05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:hsa05208]
|
05203 Viral carcinogenesis [PATH:hsa05203]
|
05230 Central carbon metabolism in cancer [PATH:hsa05230]
|
05231 Choline metabolism in cancer [PATH:hsa05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:hsa05235]
|
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:hsa05210]
|
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
1499 CTNNB1; catenin beta 1
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
332 BIRC5; baculoviral IAP repeat containing 5
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
3845 KRAS; KRAS proto-oncogene, GTPase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
842 CASP9; caspase 9
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
387 RHOA; ras homolog family member A
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
1630 DCC; DCC netrin 1 receptor
836 CASP3; caspase 3
26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
4292 MLH1; mutL homolog 1
4436 MSH2; mutS homolog 2
4437 MSH3; mutS homolog 3
2956 MSH6; mutS homolog 6
581 BAX; BCL2 associated X, apoptosis regulator
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
10018 BCL2L11; BCL2 like 11
27113 BBC3; BCL2 binding component 3
596 BCL2; BCL2 apoptosis regulator
54205 CYCS; cytochrome c, somatic
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
2069 EREG; epiregulin
374 AREG; amphiregulin
1956 EGFR; epidermal growth factor receptor
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
|
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
|
05212 Pancreatic cancer [PATH:hsa05212]
|
3845 KRAS; KRAS proto-oncogene, GTPase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
9459 ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor 6
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
842 CASP9; caspase 9
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
10928 RALBP1; ralA binding protein 1
998 CDC42; cell division cycle 42
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
7039 TGFA; transforming growth factor alpha
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
3716 JAK1; Janus kinase 1
6774 STAT3; signal transducer and activator of transcription 3
6772 STAT1; signal transducer and activator of transcription 1
7422 VEGFA; vascular endothelial growth factor A
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
675 BRCA2; BRCA2 DNA repair associated
5888 RAD51; RAD51 recombinase
|
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05729 ARHGEF6; Rho guanine nucleotide exchange factor 6
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K05448 VEGFA; vascular endothelial growth factor A
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
|
05225 Hepatocellular carcinoma [PATH:hsa05225]
|
7039 TGFA; transforming growth factor alpha
1956 EGFR; epidermal growth factor receptor
3481 IGF2; insulin like growth factor 2
3480 IGF1R; insulin like growth factor 1 receptor
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
2002 ELK1; ETS transcription factor ELK1
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
9817 KEAP1; kelch like ECH associated protein 1
4780 NFE2L2; NFE2 like bZIP transcription factor 2
3162 HMOX1; heme oxygenase 1
1728 NQO1; NAD(P)H quinone dehydrogenase 1
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
2950 GSTP1; glutathione S-transferase pi 1
7296 TXNRD1; thioredoxin reductase 1
114112 TXNRD3; thioredoxin reductase 3
10587 TXNRD2; thioredoxin reductase 2
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2549 GAB1; GRB2 associated binding protein 1
71 ACTG1; actin gamma 1
60 ACTB; actin beta
86 ACTL6A; actin like 6A
51412 ACTL6B; actin like 6B
6602 SMARCD1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
6603 SMARCD2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
6604 SMARCD3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
55274 PHF10; PHD finger protein 10
8193 DPF1; double PHD fingers 1
8110 DPF3; double PHD fingers 3
57492 ARID1B; AT-rich interaction domain 1B
8289 ARID1A; AT-rich interaction domain 1A
6605 SMARCE1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
6598 SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
6599 SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
6601 SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
6595 SMARCA2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
6597 SMARCA4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
196528 ARID2; AT-rich interaction domain 2
55193 PBRM1; polybromo 1
29117 BRD7; bromodomain containing 7
|
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04375 ELK1; ETS domain-containing protein Elk-1
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04377 MYC; Myc proto-oncogene protein
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K22197 BAF45A; BRG1-associated factor 45A
K22198 BAF45B_C; BRG1-associated factor 45B/C
K22198 BAF45B_C; BRG1-associated factor 45B/C
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11765 ARID2; AT-rich interactive domain-containing protein 2
K11757 PBRM1; protein polybromo-1
K11723 BRD7; bromodomain-containing protein 7
|
05226 Gastric cancer [PATH:hsa05226]
|
1045 CDX2; caudal type homeobox 2
4583 MUC2; mucin 2, oligomeric mucus/gel-forming
1015 CDH17; cadherin 17
83998 REG4; regenerating family member 4
5243 ABCB1; ATP binding cassette subfamily B member 1
6469 SHH; sonic hedgehog signaling molecule
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
5915 RARB; retinoic acid receptor beta
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
596 BCL2; BCL2 apoptosis regulator
4292 MLH1; mutL homolog 1
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
999 CDH1; cadherin 1
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
3728 JUP; junction plakoglobin
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
2263 FGFR2; fibroblast growth factor receptor 2
2549 GAB1; GRB2 associated binding protein 1
|
K22234 CDX2; homeobox protein CDX2
K10955 MUC2; mucin-2
K06811 CDH17; cadherin 17, LI cadherin
K22244 REG4; regenerating islet-derived protein 4
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K11988 SHH; sonic hedgehog
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K08734 MLH1; DNA mismatch repair protein MLH1
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K05689 CDH1; cadherin 1, type 1, E-cadherin
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K10056 JUP; junction plakoglobin
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
|
05214 Glioma [PATH:hsa05214]
|
05216 Thyroid cancer [PATH:hsa05216]
|
05221 Acute myeloid leukemia [PATH:hsa05221]
|
05220 Chronic myeloid leukemia [PATH:hsa05220]
|
05217 Basal cell carcinoma [PATH:hsa05217]
|
05218 Melanoma [PATH:hsa05218]
|
05211 Renal cell carcinoma [PATH:hsa05211]
|
05219 Bladder cancer [PATH:hsa05219]
|
05215 Prostate cancer [PATH:hsa05215]
|
05213 Endometrial cancer [PATH:hsa05213]
|
05224 Breast cancer [PATH:hsa05224]
|
05222 Small cell lung cancer [PATH:hsa05222]
|
05223 Non-small cell lung cancer [PATH:hsa05223]
|
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
|
6513 SLC2A1; solute carrier family 2 member 1
8829 NRP1; neuropilin 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
8295 TRRAP; transformation/transcription domain associated protein
10524 KAT5; lysine acetyltransferase 5
894 CCND2; cyclin D2
3683 ITGAL; integrin subunit alpha L
3689 ITGB2; integrin subunit beta 2
3383 ICAM1; intercellular adhesion molecule 1
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
920 CD4; CD4 molecule
7094 TLN1; talin 1
83660 TLN2; talin 2
8498 RANBP3; RAN binding protein 3
5901 RAN; RAN, member RAS oncogene family
7514 XPO1; exportin 1
811 CALR; calreticulin
821 CANX; calnexin
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
4776 NFATC4; nuclear factor of activated T cells 4
3560 IL2RB; interleukin 2 receptor subunit beta
3561 IL2RG; interleukin 2 receptor subunit gamma
3716 JAK1; Janus kinase 1
3718 JAK3; Janus kinase 3
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
3558 IL2; interleukin 2
3105 HLA-A; major histocompatibility complex, class I, A
3106 HLA-B; major histocompatibility complex, class I, B
3107 HLA-C; major histocompatibility complex, class I, C
3134 HLA-F; major histocompatibility complex, class I, F
3135 HLA-G; major histocompatibility complex, class I, G
3133 HLA-E; major histocompatibility complex, class I, E
567 B2M; beta-2-microglobulin
2224 FDPS; farnesyl diphosphate synthase
7416 VDAC1; voltage dependent anion channel 1
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
706 TSPO; translocator protein
55697 VAC14; VAC14 component of PIKFYVE complex
5902 RANBP1; RAN binding protein 1
8379 MAD1L1; mitotic arrest deficient 1 like 1
4085 MAD2L1; mitotic arrest deficient 2 like 1
701 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
9184 BUB3; BUB3 mitotic checkpoint protein
64682 ANAPC1; anaphase promoting complex subunit 1
29882 ANAPC2; anaphase promoting complex subunit 2
996 CDC27; cell division cycle 27
29945 ANAPC4; anaphase promoting complex subunit 4
51433 ANAPC5; anaphase promoting complex subunit 5
8881 CDC16; cell division cycle 16
51434 ANAPC7; anaphase promoting complex subunit 7
8697 CDC23; cell division cycle 23
10393 ANAPC10; anaphase promoting complex subunit 10
51529 ANAPC11; anaphase promoting complex subunit 11
246184 CDC26; cell division cycle 26
25847 ANAPC13; anaphase promoting complex subunit 13
25906 ANAPC15; anaphase promoting complex subunit 15
119504 ANAPC16; anaphase promoting complex subunit 16
991 CDC20; cell division cycle 20
9232 PTTG1; PTTG1 regulator of sister chromatid separation, securin
10744 PTTG2; pituitary tumor-transforming 2
9700 ESPL1; extra spindle pole bodies like 1, separase
9133 CCNB2; cyclin B2
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
595 CCND1; cyclin D1
896 CCND3; cyclin D3
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
1017 CDK2; cyclin dependent kinase 2
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
472 ATM; ATM serine/threonine kinase
545 ATR; ATR serine/threonine kinase
1111 CHEK1; checkpoint kinase 1
11200 CHEK2; checkpoint kinase 2
7157 TP53; tumor protein p53
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1739 DLG1; discs large MAGUK scaffold protein 1
5728 PTEN; phosphatase and tensin homolog
7124 TNF; tumor necrosis factor
7132 TNFRSF1A; TNF receptor superfamily member 1A
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
4316 MMP7; matrix metallopeptidase 7
3554 IL1R1; interleukin 1 receptor type 1
7850 IL1R2; interleukin 1 receptor type 2
915 CD3D; CD3 delta subunit of T-cell receptor complex
916 CD3E; CD3 epsilon subunit of T-cell receptor complex
917 CD3G; CD3 gamma subunit of T-cell receptor complex
4215 MAP3K3; mitogen-activated protein kinase kinase kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
2874 GPS2; G protein pathway suppressor 2
4055 LTBR; lymphotoxin beta receptor
958 CD40; CD40 molecule
115650 TNFRSF13C; TNF receptor superfamily member 13C
9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
5971 RELB; RELB proto-oncogene, NF-kB subunit
4791 NFKB2; nuclear factor kappa B subunit 2
7538 ZFP36; ZFP36 ring finger protein
3559 IL2RA; interleukin 2 receptor subunit alpha
3600 IL15; interleukin 15
3601 IL15RA; interleukin 15 receptor subunit alpha
3569 IL6; interleukin 6
1437 CSF2; colony stimulating factor 2
4049 LTA; lymphotoxin alpha
598 BCL2L1; BCL2 like 1
331 XIAP; X-linked inhibitor of apoptosis
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
4801 NFYB; nuclear transcription factor Y subunit beta
3108 HLA-DMA; major histocompatibility complex, class II, DM alpha
3109 HLA-DMB; major histocompatibility complex, class II, DM beta
3111 HLA-DOA; major histocompatibility complex, class II, DO alpha
3112 HLA-DOB; major histocompatibility complex, class II, DO beta
3113 HLA-DPA1; major histocompatibility complex, class II, DP alpha 1
3115 HLA-DPB1; major histocompatibility complex, class II, DP beta 1
3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1
3118 HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2
3119 HLA-DQB1; major histocompatibility complex, class II, DQ beta 1
3122 HLA-DRA; major histocompatibility complex, class II, DR alpha
3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1
3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3
3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4
3127 HLA-DRB5; major histocompatibility complex, class II, DR beta 5
6722 SRF; serum response factor
2005 ELK4; ETS transcription factor ELK4
2002 ELK1; ETS transcription factor ELK1
6688 SPI1; Spi-1 proto-oncogene
2113 ETS1; ETS proto-oncogene 1, transcription factor
2114 ETS2; ETS proto-oncogene 2, transcription factor
387332 TBPL2; TATA-box binding protein like 2
9519 TBPL1; TATA-box binding protein like 1
6908 TBP; TATA-box binding protein
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
1958 EGR1; early growth response 1
8061 FOSL1; FOS like 1, AP-1 transcription factor subunit
1959 EGR2; early growth response 2
1385 CREB1; cAMP responsive element binding protein 1
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
23373 CRTC1; CREB regulated transcription coactivator 1
200186 CRTC2; CREB regulated transcription coactivator 2
64784 CRTC3; CREB regulated transcription coactivator 3
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
8850 KAT2B; lysine acetyltransferase 2B
2648 KAT2A; lysine acetyltransferase 2A
6929 TCF3; transcription factor 3
5423 POLB; DNA polymerase beta
3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
581 BAX; BCL2 associated X, apoptosis regulator
1031 CDKN2C; cyclin dependent kinase inhibitor 2C
7015 TERT; telomerase reverse transcriptase
4487 MSX1; msh homeobox 1
4488 MSX2; msh homeobox 2
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K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1; neuropilin 1
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; G1/S-specific cyclin-D2
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K06490 ICAM1; intercellular adhesion molecule 1
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06454 CD4; T-cell surface glycoprotein CD4
K06271 TLN; talin
K06271 TLN; talin
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1; exportin-1
K08057 CALR; calreticulin
K08054 CANX; calnexin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 TSPO; translocator protein
K15305 VAC14; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K25228 APC15; anaphase-promoting complex subunit 15
K25229 APC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K12076 DLG1; disks large protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K04386 IL1R1; interleukin 1 receptor type I
K04387 IL1R2; interleukin 1 receptor type II
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K04421 MAP3K3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K15307 GPS2; G protein pathway suppressor 2
K03159 TNFRSF3; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K15308 TTP; tristetraprolin
K05068 IL2RA; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K05468 LTA; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08065 NFYB; nuclear transcription Y subunit beta
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K04378 SRF; serum response factor
K04376 ELK4; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS1; C-ets-1
K21932 ETS2; C-ets-2
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K04502 FOSL1; fos-like antigen 1
K12496 EGR2; early growth response protein 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K15309 CRTC1; CREB-regulated transcription coactivator 1
K16333 CRTC2; CREB-regulated transcription coactivator 2
K16334 CRTC3; CREB-regulated transcription coactivator 3
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K02159 BAX; apoptosis regulator BAX
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09341 MSX; homeobox protein MSX
K09341 MSX; homeobox protein MSX
|
05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
|
05161 Hepatitis B [PATH:hsa05161]
|
05160 Hepatitis C [PATH:hsa05160]
|
05171 Coronavirus disease - COVID-19 [PATH:hsa05171]
|
05164 Influenza A [PATH:hsa05164]
|
05162 Measles [PATH:hsa05162]
|
05168 Herpes simplex virus 1 infection [PATH:hsa05168]
|
05163 Human cytomegalovirus infection [PATH:hsa05163]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
|
05169 Epstein-Barr virus infection [PATH:hsa05169]
|
05165 Human papillomavirus infection [PATH:hsa05165]
|
|
|
09171 Infectious disease: bacterial
|
|
|
09174 Infectious disease: parasitic
|
05146 Amoebiasis [PATH:hsa05146]
|
05144 Malaria [PATH:hsa05144]
|
05145 Toxoplasmosis [PATH:hsa05145]
|
05140 Leishmaniasis [PATH:hsa05140]
|
05142 Chagas disease [PATH:hsa05142]
|
7099 TLR4; toll like receptor 4
148022 TICAM1; TIR domain containing adaptor molecule 1
7097 TLR2; toll like receptor 2
10333 TLR6; toll like receptor 6
54106 TLR9; toll like receptor 9
4615 MYD88; MYD88 innate immune signal transduction adaptor
3654 IRAK1; interleukin 1 receptor associated kinase 1
51135 IRAK4; interleukin 1 receptor associated kinase 4
7189 TRAF6; TNF receptor associated factor 6
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
3456 IFNB1; interferon beta 1
6352 CCL5; C-C motif chemokine ligand 5
6347 CCL2; C-C motif chemokine ligand 2
7124 TNF; tumor necrosis factor
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3569 IL6; interleukin 6
3576 CXCL8; C-X-C motif chemokine ligand 8
6348 CCL3; C-C motif chemokine ligand 3
6349 CCL3L1; C-C motif chemokine ligand 3 like 1
414062 CCL3L3; C-C motif chemokine ligand 3 like 3
3553 IL1B; interleukin 1 beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
3458 IFNG; interferon gamma
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
7132 TNFRSF1A; TNF receptor superfamily member 1A
4843 NOS2; nitric oxide synthase 2
718 C3; complement C3
811 CALR; calreticulin
712 C1QA; complement C1q A chain
713 C1QB; complement C1q B chain
714 C1QC; complement C1q C chain
3586 IL10; interleukin 10
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
1636 ACE; angiotensin I converting enzyme
3827 KNG1; kininogen 1
624 BDKRB2; bradykinin receptor B2
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
9630 GNA14; G protein subunit alpha 14
2769 GNA15; G protein subunit alpha 15
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2775 GNAO1; G protein subunit alpha o1
2778 GNAS; GNAS complex locus
2774 GNAL; G protein subunit alpha L
107 ADCY1; adenylate cyclase 1
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
7048 TGFBR2; transforming growth factor beta receptor 2
7046 TGFBR1; transforming growth factor beta receptor 1
4087 SMAD2; SMAD family member 2
5054 SERPINE1; serpin family E member 1
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
8837 CFLAR; CASP8 and FADD like apoptosis regulator
915 CD3D; CD3 delta subunit of T-cell receptor complex
916 CD3E; CD3 epsilon subunit of T-cell receptor complex
917 CD3G; CD3 gamma subunit of T-cell receptor complex
919 CD247; CD247 molecule
3558 IL2; interleukin 2
|
K10160 TLR4; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K10159 TLR2; toll-like receptor 2
K10169 TLR6; toll-like receptor 6
K10161 TLR9; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05415 IFNB; interferon beta
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2; C-C motif chemokine 2
K03156 TNF; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K05408 CCL3; C-C motif chemokine 3
K05408 CCL3; C-C motif chemokine 3
K05408 CCL3; C-C motif chemokine 3
K04519 IL1B; interleukin 1 beta
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04687 IFNG; interferon gamma
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K03990 C3; complement component 3
K08057 CALR; calreticulin
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K05443 IL10; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
K03898 KNG; kininogen
K03916 BDKRB2; bradykinin receptor B2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K03982 SERPINE1; plasminogen activator inhibitor 1
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR; CASP8 and FADD-like apoptosis regulator
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K05429 IL2; interleukin 2
|
05143 African trypanosomiasis [PATH:hsa05143]
|
|
|
09163 Immune disease
|
05310 Asthma [PATH:hsa05310]
|
05322 Systemic lupus erythematosus [PATH:hsa05322]
|
05323 Rheumatoid arthritis [PATH:hsa05323]
|
05320 Autoimmune thyroid disease [PATH:hsa05320]
|
05321 Inflammatory bowel disease [PATH:hsa05321]
|
7097 TLR2; toll like receptor 2
7099 TLR4; toll like receptor 4
7100 TLR5; toll like receptor 5
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
64127 NOD2; nucleotide binding oligomerization domain containing 2
3108 HLA-DMA; major histocompatibility complex, class II, DM alpha
3109 HLA-DMB; major histocompatibility complex, class II, DM beta
3111 HLA-DOA; major histocompatibility complex, class II, DO alpha
3112 HLA-DOB; major histocompatibility complex, class II, DO beta
3113 HLA-DPA1; major histocompatibility complex, class II, DP alpha 1
3115 HLA-DPB1; major histocompatibility complex, class II, DP beta 1
3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1
3118 HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2
3119 HLA-DQB1; major histocompatibility complex, class II, DQ beta 1
3122 HLA-DRA; major histocompatibility complex, class II, DR alpha
3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1
3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3
3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4
3127 HLA-DRB5; major histocompatibility complex, class II, DR beta 5
3458 IFNG; interferon gamma
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
6772 STAT1; signal transducer and activator of transcription 1
30009 TBX21; T-box transcription factor 21
3565 IL4; interleukin 4
3567 IL5; interleukin 5
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3595 IL12RB2; interleukin 12 receptor subunit beta 2
3594 IL12RB1; interleukin 12 receptor subunit beta 1
6775 STAT4; signal transducer and activator of transcription 4
3558 IL2; interleukin 2
3606 IL18; interleukin 18
8809 IL18R1; interleukin 18 receptor 1
8807 IL18RAP; interleukin 18 receptor accessory protein
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
7124 TNF; tumor necrosis factor
3569 IL6; interleukin 6
3552 IL1A; interleukin 1 alpha
3553 IL1B; interleukin 1 beta
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
6774 STAT3; signal transducer and activator of transcription 3
59067 IL21; interleukin 21
50615 IL21R; interleukin 21 receptor
51561 IL23A; interleukin 23 subunit alpha
149233 IL23R; interleukin 23 receptor
6097 RORC; RAR related orphan receptor C
6095 RORA; RAR related orphan receptor A
50943 FOXP3; forkhead box P3
3605 IL17A; interleukin 17A
112744 IL17F; interleukin 17F
50616 IL22; interleukin 22
3566 IL4R; interleukin 4 receptor
3561 IL2RG; interleukin 2 receptor subunit gamma
6778 STAT6; signal transducer and activator of transcription 6
2625 GATA3; GATA binding protein 3
3586 IL10; interleukin 10
3596 IL13; interleukin 13
4094 MAF; MAF bZIP transcription factor
4772 NFATC1; nuclear factor of activated T cells 1
|
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K10168 TLR5; toll-like receptor 5
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10165 NOD2; nucleotide-binding oligomerization domain-containing protein 2
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K04687 IFNG; interferon gamma
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K10166 TBX21; T-box protein 21
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05064 IL12RB2; interleukin 12 receptor beta-2
K05063 IL12RB1; interleukin 12 receptor beta-1
K11222 STAT4; signal transducer and activator of transcription 4
K05429 IL2; interleukin 2
K05482 IL18; interleukin 18
K05173 IL18R1; interleukin 18 receptor 1
K05174 IL18RAP; interleukin 18 receptor accessory protein
K04448 JUN; transcription factor AP-1
K03156 TNF; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04692 STAT3; signal transducer and activator of transcription 3
K05434 IL21; interleukin 21
K05075 IL21R; interleukin 21 receptor
K05426 IL23A; interleukin 23 subunit alpha
K05065 IL23R; interleukin 23 receptor
K08534 NR1F3; RAR-related orphan receptor gamma
K08532 NR1F1; RAR-related orphan receptor alpha
K10163 FOXP3; forkhead box P3
K05489 IL17A; interleukin 17A
K05494 IL17F; interleukin 17F
K05445 IL22; interleukin 22
K05071 IL4R; interleukin 4 receptor
K05070 IL2RG; interleukin 2 receptor gamma
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K05443 IL10; interleukin 10
K05435 IL13; interleukin 13
K09035 CMAF; transcription factor Maf
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
|
05330 Allograft rejection [PATH:hsa05330]
|
05332 Graft-versus-host disease [PATH:hsa05332]
|
05340 Primary immunodeficiency [PATH:hsa05340]
|
|
|
09164 Neurodegenerative disease
|
|
|
09165 Substance dependence
|
|
|
09166 Cardiovascular disease
|
05417 Lipid and atherosclerosis [PATH:hsa05417]
|
05418 Fluid shear stress and atherosclerosis [PATH:hsa05418]
|
05410 Hypertrophic cardiomyopathy [PATH:hsa05410]
|
05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:hsa05412]
|
05414 Dilated cardiomyopathy [PATH:hsa05414]
|
05415 Diabetic cardiomyopathy [PATH:hsa05415]
|
6513 SLC2A1; solute carrier family 2 member 1
6517 SLC2A4; solute carrier family 2 member 4
9945 GFPT2; glutamine-fructose-6-phosphate transaminase 2
2673 GFPT1; glutamine--fructose-6-phosphate transaminase 1
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
7137 TNNI3; troponin I3, cardiac type
6262 RYR2; ryanodine receptor 2
5350 PLN; phospholamban
487 ATP2A1; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
489 ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
488 ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
6667 SP1; Sp1 transcription factor
183 AGT; angiotensinogen
5972 REN; renin
1215 CMA1; chymase 1
5579 PRKCB; protein kinase C beta
177 AGER; advanced glycosylation end-product specific receptor
1536 CYBB; cytochrome b-245 beta chain
653361 NCF1; neutrophil cytosolic factor 1
1535 CYBA; cytochrome b-245 alpha chain
4688 NCF2; neutrophil cytosolic factor 2
4689 NCF4; neutrophil cytosolic factor 4
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
185 AGTR1; angiotensin II receptor type 1
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
1281 COL3A1; collagen type III alpha 1 chain
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
948 CD36; CD36 molecule (CD36 blood group)
5465 PPARA; peroxisome proliferator activated receptor alpha
1375 CPT1B; carnitine palmitoyltransferase 1B
5164 PDK2; pyruvate dehydrogenase kinase 2
5165 PDK3; pyruvate dehydrogenase kinase 3
5166 PDK4; pyruvate dehydrogenase kinase 4
5578 PRKCA; protein kinase C alpha
5580 PRKCD; protein kinase C delta
5524 PTPA; protein phosphatase 2 phosphatase activator
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
1509 CTSD; cathepsin D
5590 PRKCZ; protein kinase C zeta
1376 CPT2; carnitine palmitoyltransferase 2
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
2932 GSK3B; glycogen synthase kinase 3 beta
2998 GYS2; glycogen synthase 2
2997 GYS1; glycogen synthase 1
9882 TBC1D4; TBC1 domain family member 4
347411 MPC1L; mitochondrial pyruvate carrier 1 like
51660 MPC1; mitochondrial pyruvate carrier 1
25874 MPC2; mitochondrial pyruvate carrier 2
5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
5162 PDHB; pyruvate dehydrogenase E1 subunit beta
4535 ND1; NADH dehydrogenase subunit 1
4536 ND2; NADH dehydrogenase subunit 2
4537 ND3; NADH dehydrogenase subunit 3
4538 ND4; NADH dehydrogenase subunit 4
4539 ND4L; NADH dehydrogenase subunit 4L
4540 ND5; NADH dehydrogenase subunit 5
4541 ND6; NADH dehydrogenase subunit 6
4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1
4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2
4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3
4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1
4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2
4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
4697 NDUFA4; NDUFA4 mitochondrial complex associated
56901 NDUFA4L2; NDUFA4 mitochondrial complex associated like 2
4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5
4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8
4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9
4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10
4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11
55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13
4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2
4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4
4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5
4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6
4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7
4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10
54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1
4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2
4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3
4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5
4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6
374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7
4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8
4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
6391 SDHC; succinate dehydrogenase complex subunit C
6392 SDHD; succinate dehydrogenase complex subunit D
7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
4519 CYTB; cytochrome b
1537 CYC1; cytochrome c1
7384 UQCRC1; ubiquinol-cytochrome c reductase core protein 1
7385 UQCRC2; ubiquinol-cytochrome c reductase core protein 2
7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein
440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
7381 UQCRB; ubiquinol-cytochrome c reductase binding protein
27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
4514 COX3; cytochrome c oxidase subunit III
4512 COX1; cytochrome c oxidase subunit I
4513 COX2; cytochrome c oxidase subunit II
84701 COX4I2; cytochrome c oxidase subunit 4I2
1327 COX4I1; cytochrome c oxidase subunit 4I1
9377 COX5A; cytochrome c oxidase subunit 5A
1329 COX5B; cytochrome c oxidase subunit 5B
1337 COX6A1; cytochrome c oxidase subunit 6A1
1339 COX6A2; cytochrome c oxidase subunit 6A2
1340 COX6B1; cytochrome c oxidase subunit 6B1
125965 COX6B2; cytochrome c oxidase subunit 6B2
1345 COX6C; cytochrome c oxidase subunit 6C
1346 COX7A1; cytochrome c oxidase subunit 7A1
1347 COX7A2; cytochrome c oxidase subunit 7A2
9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
1349 COX7B; cytochrome c oxidase subunit 7B
170712 COX7B2; cytochrome c oxidase subunit 7B2
1350 COX7C; cytochrome c oxidase subunit 7C
341947 COX8C; cytochrome c oxidase subunit 8C
1351 COX8A; cytochrome c oxidase subunit 8A
498 ATP5F1A; ATP synthase F1 subunit alpha
506 ATP5F1B; ATP synthase F1 subunit beta
509 ATP5F1C; ATP synthase F1 subunit gamma
513 ATP5F1D; ATP synthase F1 subunit delta
514 ATP5F1E; ATP synthase F1 subunit epsilon
4508 ATP6; ATP synthase F0 subunit 6
515 ATP5PB; ATP synthase peripheral stalk-membrane subunit b
516 ATP5MC1; ATP synthase membrane subunit c locus 1
517 ATP5MC2; ATP synthase membrane subunit c locus 2
518 ATP5MC3; ATP synthase membrane subunit c locus 3
10476 ATP5PD; ATP synthase peripheral stalk subunit d
539 ATP5PO; ATP synthase peripheral stalk subunit OSCP
522 ATP5PF; ATP synthase peripheral stalk subunit F6
4509 ATP8; ATP synthase F0 subunit 8
7416 VDAC1; voltage dependent anion channel 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
10105 PPIF; peptidylprolyl isomerase F
5582 PRKCG; protein kinase C gamma
4846 NOS3; nitric oxide synthase 3
2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase
142 PARP1; poly(ADP-ribose) polymerase 1
2539 G6PD; glucose-6-phosphate dehydrogenase
2936 GSR; glutathione-disulfide reductase
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
1636 ACE; angiotensin I converting enzyme
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K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K12044 TNNI3; troponin I, cardiac muscle
K04962 RYR2; ryanodine receptor 2
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04684 SP1; transcription factor Sp1
K09821 AGT; angiotensinogen
K01380 REN; renin [EC:3.4.23.15]
K01329 CMA1; chymase [EC:3.4.21.39]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19722 AGER; receptor for advanced glycosylation end products
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1; neutrophil cytosolic factor 1
K08009 CYBA; cytochrome b-245, alpha polypeptide
K08010 NCF2; neutrophil cytosolic factor 2
K08012 NCF4; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04166 AGTR1; angiotensin II receptor type 1
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K06259 CD36; CD36 antigen
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K17605 PPP2R4; serine/threonine-protein phosphatase 2A activator
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K08766 CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K17902 TBC1D4; TBC1 domain family member 4
K22138 MPC1; mitochondrial pyruvate carrier 1
K22138 MPC1; mitochondrial pyruvate carrier 1
K22139 MPC2; mitochondrial pyruvate carrier 2
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
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05416 Viral myocarditis [PATH:hsa05416]
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09167 Endocrine and metabolic disease
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04930 Type II diabetes mellitus [PATH:hsa04930]
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04940 Type I diabetes mellitus [PATH:hsa04940]
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04950 Maturity onset diabetes of the young [PATH:hsa04950]
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04936 Alcoholic liver disease [PATH:hsa04936]
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04932 Non-alcoholic fatty liver disease [PATH:hsa04932]
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04931 Insulin resistance [PATH:hsa04931]
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04933 AGE-RAGE signaling pathway in diabetic complications [PATH:hsa04933]
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7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7040 TGFB1; transforming growth factor beta 1
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
2335 FN1; fibronectin 1
1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
1281 COL3A1; collagen type III alpha 1 chain
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
183 AGT; angiotensinogen
185 AGTR1; angiotensin II receptor type 1
177 AGER; advanced glycosylation end-product specific receptor
27035 NOX1; NADPH oxidase 1
1536 CYBB; cytochrome b-245 beta chain
50507 NOX4; NADPH oxidase 4
5333 PLCD1; phospholipase C delta 1
113026 PLCD3; phospholipase C delta 3
84812 PLCD4; phospholipase C delta 4
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
51196 PLCE1; phospholipase C epsilon 1
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5580 PRKCD; protein kinase C delta
5581 PRKCE; protein kinase C epsilon
5590 PRKCZ; protein kinase C zeta
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
6347 CCL2; C-C motif chemokine ligand 2
5054 SERPINE1; serpin family E member 1
6401 SELE; selectin E
7412 VCAM1; vascular cell adhesion molecule 1
3383 ICAM1; intercellular adhesion molecule 1
4313 MMP2; matrix metallopeptidase 2
3552 IL1A; interleukin 1 alpha
3553 IL1B; interleukin 1 beta
3569 IL6; interleukin 6
3576 CXCL8; C-X-C motif chemokine ligand 8
7124 TNF; tumor necrosis factor
2152 F3; coagulation factor III, tissue factor
1906 EDN1; endothelin 1
7056 THBD; thrombomodulin
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
5970 RELA; RELA proto-oncogene, NF-kB subunit
4790 NFKB1; nuclear factor kappa B subunit 1
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
1729 DIAPH1; diaphanous related formin 1
5879 RAC1; Rac family small GTPase 1
998 CDC42; cell division cycle 42
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
4846 NOS3; nitric oxide synthase 3
2308 FOXO1; forkhead box O1
596 BCL2; BCL2 apoptosis regulator
581 BAX; BCL2 associated X, apoptosis regulator
836 CASP3; caspase 3
3717 JAK2; Janus kinase 2
6774 STAT3; signal transducer and activator of transcription 3
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
4772 NFATC1; nuclear factor of activated T cells 1
6772 STAT1; signal transducer and activator of transcription 1
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
595 CCND1; cyclin D1
1019 CDK4; cyclin dependent kinase 4
1958 EGR1; early growth response 1
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K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K05717 FN1; fibronectin 1
K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K09821 AGT; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K19722 AGER; receptor for advanced glycosylation end products
K08008 NOX1; NADPH oxidase 1
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4; NADPH oxidase 4 [EC:1.6.3.-]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K14624 CCL2; C-C motif chemokine 2
K03982 SERPINE1; plasminogen activator inhibitor 1
K06494 SELE; selectin, endothelial cell
K06527 VCAM1; vascular cell adhesion molecule 1
K06490 ICAM1; intercellular adhesion molecule 1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K03156 TNF; tumor necrosis factor superfamily, member 2
K03901 F3; coagulation factor III (tissue factor)
K16366 EDN1; endothelin-1
K03907 THBD; thrombomodulin
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05740 DIAPH1; diaphanous 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04393 CDC42; cell division control protein 42
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K07201 FOXO1; forkhead box protein O1
K02161 BCL2; apoptosis regulator Bcl-2
K02159 BAX; apoptosis regulator BAX
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K11220 STAT1; signal transducer and activator of transcription 1
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K09203 EGR1; early growth response protein 1
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04934 Cushing syndrome [PATH:hsa04934]
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)