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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:hsa04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:hsa04012]
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04014 Ras signaling pathway [PATH:hsa04014]
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04015 Rap1 signaling pathway [PATH:hsa04015]
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04310 Wnt signaling pathway [PATH:hsa04310]
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64840 PORCN; porcupine O-acyltransferase
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
9350 CER1; cerberus 1, DAN family BMP antagonist
147111 NOTUM; notum, palmitoleoyl-protein carboxylesterase
11197 WIF1; WNT inhibitory factor 1
5176 SERPINF1; serpin family F member 1
50964 SOST; sclerostin
22943 DKK1; dickkopf WNT signaling pathway inhibitor 1
27123 DKK2; dickkopf WNT signaling pathway inhibitor 2
27121 DKK4; dickkopf WNT signaling pathway inhibitor 4
6422 SFRP1; secreted frizzled related protein 1
6423 SFRP2; secreted frizzled related protein 2
6424 SFRP4; secreted frizzled related protein 4
6425 SFRP5; secreted frizzled related protein 5
284654 RSPO1; R-spondin 1
340419 RSPO2; R-spondin 2
84870 RSPO3; R-spondin 3
343637 RSPO4; R-spondin 4
55366 LGR4; leucine rich repeat containing G protein-coupled receptor 4
8549 LGR5; leucine rich repeat containing G protein-coupled receptor 5
59352 LGR6; leucine rich repeat containing G protein-coupled receptor 6
54894 RNF43; ring finger protein 43
84133 ZNRF3; zinc and ring finger 3
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
25805 BAMBI; BMP and activin membrane bound inhibitor
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
1457 CSNK2A1; casein kinase 2 alpha 1
1459 CSNK2A2; casein kinase 2 alpha 2
283106 CSNK2A3; casein kinase 2 alpha 3
1460 CSNK2B; casein kinase 2 beta
85407 NKD1; NKD inhibitor of WNT signaling pathway 1
85409 NKD2; NKD inhibitor of WNT signaling pathway 2
80319 CXXC4; CXXC finger protein 4
59343 SENP2; SUMO specific peptidase 2
2932 GSK3B; glycogen synthase kinase 3 beta
1499 CTNNB1; catenin beta 1
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
56998 CTNNBIP1; catenin beta interacting protein 1
25776 CBY1; chibby family member 1, beta catenin antagonist
57680 CHD8; chromodomain helicase DNA binding protein 8
64321 SOX17; SRY-box transcription factor 17
1487 CTBP1; C-terminal binding protein 1
1488 CTBP2; C-terminal binding protein 2
102723796 TLE7; TLE family member 7
7088 TLE1; TLE family member 1, transcriptional corepressor
7089 TLE2; TLE family member 2, transcriptional corepressor
7090 TLE3; TLE family member 3, transcriptional corepressor
7091 TLE4; TLE family member 4, transcriptional corepressor
79816 TLE6; TLE family member 6, subcortical maternal complex member
1501 CTNND2; catenin delta 2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
8607 RUVBL1; RuvB like AAA ATPase 1
4089 SMAD4; SMAD family member 4
4088 SMAD3; SMAD family member 3
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
51701 NLK; nemo like kinase
4609 MYC; MYC proto-oncogene, bHLH transcription factor
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
8061 FOSL1; FOS like 1, AP-1 transcription factor subunit
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
8840 CCN4; cellular communication network factor 4
5467 PPARD; peroxisome proliferator activated receptor delta
4316 MMP7; matrix metallopeptidase 7
5663 PSEN1; presenilin 1
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
7157 TP53; tumor protein p53
6477 SIAH1; siah E3 ubiquitin protein ligase 1
27101 CACYBP; calcyclin binding protein
6500 SKP1; S-phase kinase associated protein 1
6907 TBL1X; transducin beta like 1 X-linked
90665 TBL1Y; transducin beta like 1 Y-linked
79718 TBL1XR1; TBL1X receptor 1
8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
23291 FBXW11; F-box and WD repeat domain containing 11
8454 CUL1; cullin 1
9978 RBX1; ring-box 1
2239 GPC4; glypican 4
4919 ROR1; receptor tyrosine kinase like orphan receptor 1
4920 ROR2; receptor tyrosine kinase like orphan receptor 2
6259 RYK; receptor like tyrosine kinase
57216 VANGL2; VANGL planar cell polarity protein 2
81839 VANGL1; VANGL planar cell polarity protein 1
144165 PRICKLE1; prickle planar cell polarity protein 1
166336 PRICKLE2; prickle planar cell polarity protein 2
29964 PRICKLE4; prickle planar cell polarity protein 4
4007 PRICKLE3; prickle planar cell polarity protein 3
27130 INVS; inversin
23002 DAAM1; dishevelled associated activator of morphogenesis 1
23500 DAAM2; dishevelled associated activator of morphogenesis 2
387 RHOA; ras homolog family member A
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
4776 NFATC4; nuclear factor of activated T cells 4
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K00181 PORCN; O-palmitoleoyl transferase [EC:2.3.1.250]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K01645 CER1; cerberus 1
K19882 NOTUM; O-palmitoleoyl-L-serine hydrolase [EC:3.1.1.98]
K01691 WIF1; WNT inhibitory factor 1
K19614 SERPINF1; pigment epithelium-derived factor
K16834 SOST; sclerostin
K02165 DKK; dickkopf
K02165 DKK; dickkopf
K02165 DKK; dickkopf
K02166 SFRP1; secreted frizzled-related protein 1
K02176 SFRP2; secreted frizzled-related protein 2
K02185 SFRP4; secreted frizzled-related protein 4
K02222 SFRP5; secreted frizzled-related protein 5
K19471 RSPO1; R-spondin 1
K23097 RSPO2; R-spondin 2
K23098 RSPO3; R-spondin 3
K23099 RSPO4; R-spondin 4
K04309 LGR4; leucine-rich repeat-containing G protein-coupled receptor 4
K04308 LGR5; leucine-rich repeat-containing G protein-coupled receptor 5
K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
K15694 RNF43; RING finger protein 43 [EC:2.3.2.27]
K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K10162 BAMBI; BMP and activin membrane-bound inhibitor
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K03344 IDAX; Dvl-binding protein IDAX
K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04493 ICAT; beta-catenin-interacting protein 1 (inhibitor of beta-catenin and Tcf-4)
K23402 CBY1; protein chibby 1
K04494 CHD8; chromodomain helicase DNA binding protein 8 [EC:3.6.4.12]
K04495 SOX17; transcription factor SOX17 (SOX group F)
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K23491 CTNND2; catenin delta-2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04499 RUVBL1; RuvB-like protein 1 [EC:3.6.4.12]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K04448 JUN; transcription factor AP-1
K04502 FOSL1; fos-like antigen 1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K22471 CCN4; CCN family member 4
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K04505 PSEN1; presenilin 1 [EC:3.4.23.-]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04451 TP53; tumor protein p53
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K04507 CACYBP; calcyclin binding protein
K03094 SKP1; S-phase kinase-associated protein 1
K04508 TBL1; transducin (beta)-like 1
K04508 TBL1; transducin (beta)-like 1
K04508 TBL1; transducin (beta)-like 1
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K08110 GPC4; glypican 4
K05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
K05123 ROR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K04510 VANGL; vang-like
K04510 VANGL; vang-like
K04511 PRICKLE; prickle
K04511 PRICKLE; prickle
K04511 PRICKLE; prickle
K04511 PRICKLE; prickle
K19626 INVS; inversin
K04512 DAAM; dishevelled associated activator of morphogenesis
K04512 DAAM; dishevelled associated activator of morphogenesis
K04513 RHOA; Ras homolog gene family, member A
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
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04330 Notch signaling pathway [PATH:hsa04330]
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04340 Hedgehog signaling pathway [PATH:hsa04340]
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5727 PTCH1; patched 1
8643 PTCH2; patched 2
6608 SMO; smoothened, frizzled class receptor
23432 GPR161; G protein-coupled receptor 161
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
1455 CSNK1G2; casein kinase 1 gamma 2
1456 CSNK1G3; casein kinase 1 gamma 3
53944 CSNK1G1; casein kinase 1 gamma 1
1453 CSNK1D; casein kinase 1 delta
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
2932 GSK3B; glycogen synthase kinase 3 beta
2735 GLI1; GLI family zinc finger 1
2736 GLI2; GLI family zinc finger 2
2737 GLI3; GLI family zinc finger 3
51684 SUFU; SUFU negative regulator of hedgehog signaling
374654 KIF7; kinesin family member 7
64399 HHIP; hedgehog interacting protein
595 CCND1; cyclin D1
894 CCND2; cyclin D2
596 BCL2; BCL2 apoptosis regulator
8454 CUL1; cullin 1
8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
23291 FBXW11; F-box and WD repeat domain containing 11
55733 HHAT; hedgehog acyltransferase
57467 HHATL; hedgehog acyltransferase like
6469 SHH; sonic hedgehog signaling molecule
3549 IHH; Indian hedgehog signaling molecule
50846 DHH; desert hedgehog signaling molecule
84976 DISP1; dispatched RND transporter family member 1
57758 SCUBE2; signal peptide, CUB domain and EGF like domain containing 2
91653 BOC; BOC cell adhesion associated, oncogene regulated
50937 CDON; cell adhesion associated, oncogene regulated
2619 GAS1; growth arrest specific 1
4036 LRP2; LDL receptor related protein 2
730094 MOSMO; modulator of smoothened
1954 MEGF8; multiple EGF like domains 8
23295 MGRN1; mahogunin ring finger 1
57154 SMURF1; SMAD specific E3 ubiquitin protein ligase 1
64750 SMURF2; SMAD specific E3 ubiquitin protein ligase 2
156 GRK2; G protein-coupled receptor kinase 2
157 GRK3; G protein-coupled receptor kinase 3
2121 EVC; EvC ciliary complex subunit 1
132884 EVC2; EvC ciliary complex subunit 2
84455 EFCAB7; EF-hand calcium binding domain 7
23288 IQCE; IQ motif containing E
408 ARRB1; arrestin beta 1
409 ARRB2; arrestin beta 2
11127 KIF3A; kinesin family member 3A
8452 CUL3; cullin 3
8405 SPOP; speckle type BTB/POZ protein
339745 SPOPL; speckle type BTB/POZ protein like
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K06225 PTCH1; patched 1
K11101 PTCH2; patched 2
K06226 SMO; smoothened
K08439 GPR161; G protein-coupled receptor 161
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K06229 SUFU; suppressor of fused
K18806 KIF7; kinesin family member 7
K06231 HHIP; hedgehog interacting protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K02161 BCL2; apoptosis regulator Bcl-2
K03347 CUL1; cullin 1
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K24678 HHAT; protein-cysteine N-palmitoyltransferase HHAT [EC:2.3.1.-]
K24679 HHATL; protein-cysteine N-palmitoyltransferase HHAT-like protein
K11988 SHH; sonic hedgehog
K11989 IHH; indian hedgehog
K11990 DHH; desert hedgehog
K24680 DISP1; protein dispatched 1
K24706 SCUBE2; signal peptide, CUB and EGF-like domain-containing protein 2
K20020 BOC; brother of CDO
K20033 CDON; cell adhesion molecule-related/down-regulated by oncogenes
K06232 GAS1; growth arrest-specific 1
K06233 LRP2; low density lipoprotein-related protein 2
K23663 MOSMO; modulator of smoothened protein
K23664 MEGF8; multipile epidermal growth factor-like domains protein 8
K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K19605 EVC1; ellis van creveld syndrome protein 1
K19608 EVC2; ellis van creveld syndrome protein 2
K23852 EFCAB7; EF-hand calcium-binding domain-containing protein 7
K24677 IQCE; IQ domain-contaning protein E
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
K10394 KIF3A; kinesin family member 3A
K03869 CUL3; cullin 3
K10523 SPOP; speckle-type POZ protein
K10523 SPOP; speckle-type POZ protein
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:hsa04350]
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04390 Hippo signaling pathway [PATH:hsa04390]
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286204 CRB2; crumbs cell polarity complex component 2
23418 CRB1; crumbs cell polarity complex component 1
56288 PARD3; par-3 family cell polarity regulator
50855 PARD6A; par-6 family cell polarity regulator alpha
84552 PARD6G; par-6 family cell polarity regulator gamma
84612 PARD6B; par-6 family cell polarity regulator beta
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
10207 PATJ; PATJ crumbs cell polarity complex component
64398 MPP5; membrane palmitoylated protein 5
154796 AMOT; angiomotin
10413 YAP1; Yes1 associated transcriptional regulator
25937 WWTR1; WW domain containing transcription regulator 1
999 CDH1; cadherin 1
8994 LIMD1; LIM domain containing 1
84962 AJUBA; ajuba LIM protein
126374 WTIP; WT1 interacting protein
4771 NF2; neurofibromin 2
23286 WWC1; WW and C2 domain containing 1
79981 FRMD1; FERM domain containing 1
122786 FRMD6; FERM domain containing 6
60485 SAV1; salvador family WW domain containing protein 1
6788 STK3; serine/threonine kinase 3
166824 RASSF6; Ras association domain family member 6
11186 RASSF1; Ras association domain family member 1
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
26524 LATS2; large tumor suppressor kinase 2
9113 LATS1; large tumor suppressor kinase 1
55233 MOB1A; MOB kinase activator 1A
92597 MOB1B; MOB kinase activator 1B
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
7159 TP53BP2; tumor protein p53 binding protein 2
3993 LLGL2; LLGL scribble cell polarity complex component 2
3996 LLGL1; LLGL scribble cell polarity complex component 1
23513 SCRIB; scribble planar cell polarity protein
1739 DLG1; discs large MAGUK scaffold protein 1
1740 DLG2; discs large MAGUK scaffold protein 2
1741 DLG3; discs large MAGUK scaffold protein 3
1742 DLG4; discs large MAGUK scaffold protein 4
9231 DLG5; discs large MAGUK scaffold protein 5
1453 CSNK1D; casein kinase 1 delta
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
23291 FBXW11; F-box and WD repeat domain containing 11
7161 TP73; tumor protein p73
27113 BBC3; BCL2 binding component 3
7003 TEAD1; TEA domain transcription factor 1
7004 TEAD4; TEA domain transcription factor 4
7005 TEAD3; TEA domain transcription factor 3
8463 TEAD2; TEA domain transcription factor 2
1490 CCN2; cellular communication network factor 2
2736 GLI2; GLI family zinc finger 2
374 AREG; amphiregulin
332 BIRC5; baculoviral IAP repeat containing 5
174 AFP; alpha fetoprotein
3689 ITGB2; integrin subunit beta 2
2246 FGF1; fibroblast growth factor 1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4092 SMAD7; SMAD family member 7
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
5054 SERPINE1; serpin family E member 1
650 BMP2; bone morphogenetic protein 2
652 BMP4; bone morphogenetic protein 4
653 BMP5; bone morphogenetic protein 5
654 BMP6; bone morphogenetic protein 6
655 BMP7; bone morphogenetic protein 7
656 BMP8B; bone morphogenetic protein 8b
353500 BMP8A; bone morphogenetic protein 8a
8200 GDF5; growth differentiation factor 5
392255 GDF6; growth differentiation factor 6
151449 GDF7; growth differentiation factor 7
268 AMH; anti-Mullerian hormone
657 BMPR1A; bone morphogenetic protein receptor type 1A
658 BMPR1B; bone morphogenetic protein receptor type 1B
659 BMPR2; bone morphogenetic protein receptor type 2
4086 SMAD1; SMAD family member 1
3397 ID1; inhibitor of DNA binding 1, HLH protein
3398 ID2; inhibitor of DNA binding 2
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
2932 GSK3B; glycogen synthase kinase 3 beta
1499 CTNNB1; catenin beta 1
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
8312 AXIN1; axin 1
8313 AXIN2; axin 2
85407 NKD1; NKD inhibitor of WNT signaling pathway 1
85409 NKD2; NKD inhibitor of WNT signaling pathway 2
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
6657 SOX2; SRY-box transcription factor 2
6591 SNAI2; snail family transcriptional repressor 2
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
71 ACTG1; actin gamma 1
60 ACTB; actin beta
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
|
K16681 CRB; protein crumbs
K16681 CRB; protein crumbs
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06092 INADL; InaD-like protein
K06091 MPP5; MAGUK p55 subfamily member 5
K16819 AMOT; angiomotin
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K16686 SAV1; scaffold protein salvador
K04412 STK3; serine/threonine kinase 3
K09854 RASSF6; Ras association domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16823 TP53BP2; apoptosis-stimulating of p53 protein 2
K06094 LLGL; lethal(2) giant larvae protein
K06094 LLGL; lethal(2) giant larvae protein
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K11828 DLG4; discs large protein 4
K24050 DLG5; discs large protein 5
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10148 TP73; tumor protein p73
K10132 BBC3; Bcl-2-binding component 3
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K16798 GLI2; zinc finger protein GLI2
K09782 AREG; amphiregulin
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16144 AFP; alpha-fetoprotein
K06464 ITGB2; integrin beta 2
K18496 FGF1; fibroblast growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03982 SERPINE1; plasminogen activator inhibitor 1
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16796 SOX2; transcription factor SOX2 (SOX group B)
K05706 SNAI2; snail 2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
|
04370 VEGF signaling pathway [PATH:hsa04370]
|
04371 Apelin signaling pathway [PATH:hsa04371]
|
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
55811 ADCY10; adenylate cyclase 10
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
3991 LIPE; lipase E, hormone sensitive type
8862 APLN; apelin
187 APLNR; apelin receptor
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
6261 RYR1; ryanodine receptor 1
6262 RYR2; ryanodine receptor 2
6263 RYR3; ryanodine receptor 3
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
4842 NOS1; nitric oxide synthase 1
4843 NOS2; nitric oxide synthase 2
4846 NOS3; nitric oxide synthase 3
5581 PRKCE; protein kinase C epsilon
6548 SLC9A1; solute carrier family 9 member A1
6546 SLC8A1; solute carrier family 8 member A1
6543 SLC8A2; solute carrier family 8 member A2
6547 SLC8A3; solute carrier family 8 member A3
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
4633 MYL2; myosin light chain 2
4634 MYL3; myosin light chain 3
4635 MYL4; myosin light chain 4
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
6194 RPS6; ribosomal protein S6
5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
1958 EGR1; early growth response 1
6696 SPP1; secreted phosphoprotein 1
182 JAG1; jagged canonical Notch ligand 1
4854 NOTCH3; notch receptor 3
595 CCND1; cyclin D1
5140 PDE3B; phosphodiesterase 3B
5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
8678 BECN1; beclin 1
441925 BECN2; beclin 2
11337 GABARAP; GABA type A receptor-associated protein
23710 GABARAPL1; GABA type A receptor associated protein like 1
11345 GABARAPL2; GABA type A receptor associated protein like 2
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
5346 PLIN1; perilipin 1
10891 PPARGC1A; PPARG coactivator 1 alpha
7350 UCP1; uncoupling protein 1
4899 NRF1; nuclear respiratory factor 1
7019 TFAM; transcription factor A, mitochondrial
10365 KLF2; Kruppel like factor 2
8877 SPHK1; sphingosine kinase 1
56848 SPHK2; sphingosine kinase 2
10672 GNA13; G protein subunit alpha 13
814 CAMK4; calcium/calmodulin dependent protein kinase IV
9759 HDAC4; histone deacetylase 4
10014 HDAC5; histone deacetylase 5
4205 MEF2A; myocyte enhancer factor 2A
4207 BORCS8-MEF2B; BORCS8-MEF2B readthrough
100271849 MEF2B; myocyte enhancer factor 2B
4208 MEF2C; myocyte enhancer factor 2C
4209 MEF2D; myocyte enhancer factor 2D
7046 TGFBR1; transforming growth factor beta receptor 1
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
59 ACTA2; actin alpha 2, smooth muscle
999 CDH1; cadherin 1
1490 CCN2; cellular communication network factor 2
185 AGTR1; angiotensin II receptor type 1
5054 SERPINE1; serpin family E member 1
5327 PLAT; plasminogen activator, tissue type
|
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K05225 APLN; apelin
K04174 APLNR; apelin receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K10351 MYL2; myosin regulatory light chain 2
K12749 MYL3; myosin light chain 3
K12750 MYL4; myosin light chain 4
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K09203 EGR1; early growth response protein 1
K06250 SPP1; secreted phosphoprotein 1
K06052 JAG1; jagged-1
K20995 NOTCH3; Notch 3
K04503 CCND1; G1/S-specific cyclin-D1
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K08334 BECN; beclin
K08334 BECN; beclin
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K08768 PLIN1; perilipin-1
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K08769 UCP1; solute carrier family 25 (mitochondrial uncoupling protein), member 7
K11831 NRF1; nuclear respiratory factor 1
K11830 TFAM; transcription factor A, mitochondrial
K17845 KLF2; krueppel-like factor 2
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K09262 MEF2D; MADS-box transcription enhancer factor 2D
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K12313 ACTA2; actin, aortic smooth muscle
K05689 CDH1; cadherin 1, type 1, E-cadherin
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K04166 AGTR1; angiotensin II receptor type 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
|
04630 JAK-STAT signaling pathway [PATH:hsa04630]
|
3558 IL2; interleukin 2
3562 IL3; interleukin 3
3565 IL4; interleukin 4
3567 IL5; interleukin 5
3569 IL6; interleukin 6
3574 IL7; interleukin 7
3578 IL9; interleukin 9
3586 IL10; interleukin 10
3589 IL11; interleukin 11
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3596 IL13; interleukin 13
3600 IL15; interleukin 15
53342 IL17D; interleukin 17D
29949 IL19; interleukin 19
50604 IL20; interleukin 20
59067 IL21; interleukin 21
50616 IL22; interleukin 22
51561 IL23A; interleukin 23 subunit alpha
11009 IL24; interleukin 24
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
3458 IFNG; interferon gamma
338376 IFNE; interferon epsilon
56832 IFNK; interferon kappa
282618 IFNL1; interferon lambda 1
282616 IFNL2; interferon lambda 2
282617 IFNL3; interferon lambda 3
3467 IFNW1; interferon omega 1
5008 OSM; oncostatin M
3976 LIF; LIF interleukin 6 family cytokine
85480 TSLP; thymic stromal lymphopoietin
1489 CTF1; cardiotrophin 1
1437 CSF2; colony stimulating factor 2
1270 CNTF; ciliary neurotrophic factor
1440 CSF3; colony stimulating factor 3
2056 EPO; erythropoietin
2688 GH1; growth hormone 1
2689 GH2; growth hormone 2
1442 CSH1; chorionic somatomammotropin hormone 1
1443 CSH2; chorionic somatomammotropin hormone 2
3952 LEP; leptin
7066 THPO; thrombopoietin
5617 PRL; prolactin
1950 EGF; epidermal growth factor
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
3559 IL2RA; interleukin 2 receptor subunit alpha
3560 IL2RB; interleukin 2 receptor subunit beta
3561 IL2RG; interleukin 2 receptor subunit gamma
3563 IL3RA; interleukin 3 receptor subunit alpha
3566 IL4R; interleukin 4 receptor
3568 IL5RA; interleukin 5 receptor subunit alpha
3570 IL6R; interleukin 6 receptor
3575 IL7R; interleukin 7 receptor
3581 IL9R; interleukin 9 receptor
3587 IL10RA; interleukin 10 receptor subunit alpha
3588 IL10RB; interleukin 10 receptor subunit beta
3590 IL11RA; interleukin 11 receptor subunit alpha
3594 IL12RB1; interleukin 12 receptor subunit beta 1
3595 IL12RB2; interleukin 12 receptor subunit beta 2
3597 IL13RA1; interleukin 13 receptor subunit alpha 1
3598 IL13RA2; interleukin 13 receptor subunit alpha 2
3601 IL15RA; interleukin 15 receptor subunit alpha
53832 IL20RA; interleukin 20 receptor subunit alpha
53833 IL20RB; interleukin 20 receptor subunit beta
50615 IL21R; interleukin 21 receptor
58985 IL22RA1; interleukin 22 receptor subunit alpha 1
116379 IL22RA2; interleukin 22 receptor subunit alpha 2
149233 IL23R; interleukin 23 receptor
9466 IL27RA; interleukin 27 receptor subunit alpha
3572 IL6ST; interleukin 6 signal transducer
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
163702 IFNLR1; interferon lambda receptor 1
9180 OSMR; oncostatin M receptor
3977 LIFR; LIF receptor subunit alpha
64109 CRLF2; cytokine receptor like factor 2
1271 CNTFR; ciliary neurotrophic factor receptor
1438 CSF2RA; colony stimulating factor 2 receptor subunit alpha
1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
1441 CSF3R; colony stimulating factor 3 receptor
2057 EPOR; erythropoietin receptor
2690 GHR; growth hormone receptor
3953 LEPR; leptin receptor
4352 MPL; MPL proto-oncogene, thrombopoietin receptor
5618 PRLR; prolactin receptor
1956 EGFR; epidermal growth factor receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
7297 TYK2; tyrosine kinase 2
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
6774 STAT3; signal transducer and activator of transcription 3
6775 STAT4; signal transducer and activator of transcription 4
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
6778 STAT6; signal transducer and activator of transcription 6
1154 CISH; cytokine inducible SH2 containing protein
8651 SOCS1; suppressor of cytokine signaling 1
8835 SOCS2; suppressor of cytokine signaling 2
9021 SOCS3; suppressor of cytokine signaling 3
122809 SOCS4; suppressor of cytokine signaling 4
9655 SOCS5; suppressor of cytokine signaling 5
30837 SOCS7; suppressor of cytokine signaling 7
9306 SOCS6; suppressor of cytokine signaling 6
596 BCL2; BCL2 apoptosis regulator
4170 MCL1; MCL1 apoptosis regulator, BCL2 family member
598 BCL2L1; BCL2 like 1
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
316 AOX1; aldehyde oxidase 1
2670 GFAP; glial fibrillary acidic protein
10254 STAM2; signal transducing adaptor molecule 2
8027 STAM; signal transducing adaptor molecule
5771 PTPN2; protein tyrosine phosphatase non-receptor type 2
5777 PTPN6; protein tyrosine phosphatase non-receptor type 6
10379 IRF9; interferon regulatory factor 9
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
8554 PIAS1; protein inhibitor of activated STAT 1
9063 PIAS2; protein inhibitor of activated STAT 2
10401 PIAS3; protein inhibitor of activated STAT 3
51588 PIAS4; protein inhibitor of activated STAT 4
2273 FHL1; four and a half LIM domains 1
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
|
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05443 IL10; interleukin 10
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05492 IL17D; interleukin 17D
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K05434 IL21; interleukin 21
K05445 IL22; interleukin 22
K05426 IL23A; interleukin 23 subunit alpha
K22668 IL24; interleukin 24
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1; interferon lambda 1
K22669 IFNL2_3; interferon lambda 2/3
K22669 IFNL2_3; interferon lambda 2/3
K05440 IFNW; interferon omega
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05436 TSLP; thymic stromal lymphopoietin
K05422 CTF1; cardiotrophin 1
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K05420 CNTF; ciliary neurotrophic factor
K05423 CSF3; granulocyte colony-stimulating factor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05438 GH; growth hormone
K05438 GH; growth hormone
K05438 GH; growth hormone
K05424 LEP; leptin
K06854 THPO; thrombopoietin
K05439 PRL; prolactin
K04357 EGF; epidermal growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05072 IL7R; interleukin 7 receptor
K05073 IL9R; interleukin 9 receptor
K05134 IL10RA; interleukin 10 receptor alpha
K05135 IL10RB; interleukin 10 receptor beta
K05056 IL11RA; interleukin 11 receptor alpha
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05077 IL13RA2; interleukin 13 receptor alpha-2
K05074 IL15RA; interleukin 15 receptor alpha
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05075 IL21R; interleukin 21 receptor
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05139 IL22RA2; interleukin 22 receptor alpha 2
K05065 IL23R; interleukin 23 receptor
K19598 IL27RA; interleukin 27 receptor alpha
K05060 IL6ST; interleukin 6 signal transducer
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05140 IFNLR1; interferon lambda receptor 1
K05057 OSMR; oncostatin M receptor
K05058 LIFR; leukemia inhibitory factor receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K05059 CNTFR; ciliary neurotrophic factor receptor
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K04738 CSF2RB; cytokine receptor common subunit beta
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05062 LEPR; leptin receptor
K05082 TPOR; thrombopoietin receptor
K05081 PRLR; prolactin receptor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04701 CISH; cytokine inducible SH2-containing protein
K04694 SOCS1; suppressor of cytokine signaling 1
K04695 SOCS2; suppressor of cytokine signaling 2
K04696 SOCS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K04698 SOCS5; suppressor of cytokine signaling 5
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K02161 BCL2; apoptosis regulator Bcl-2
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K05640 GFAP; glial fibrillary acidic protein
K04705 STAM; signal transducing adaptor molecule
K04705 STAM; signal transducing adaptor molecule
K18026 PTPN2; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
K05697 PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K04693 IRF9; interferon regulatory factor 9
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K14365 FHL1; four and a half LIM domains protein 1
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
|
04064 NF-kappa B signaling pathway [PATH:hsa04064]
|
04668 TNF signaling pathway [PATH:hsa04668]
|
04066 HIF-1 signaling pathway [PATH:hsa04066]
|
04068 FoxO signaling pathway [PATH:hsa04068]
|
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4089 SMAD4; SMAD family member 4
4088 SMAD3; SMAD family member 3
6794 STK11; serine/threonine kinase 11
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
51701 NLK; nemo like kinase
6502 SKP2; S-phase kinase associated protein 2
4193 MDM2; MDM2 proto-oncogene
80854 SETD7; SET domain containing 7, histone lysine methyltransferase
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
23411 SIRT1; sirtuin 1
7874 USP7; ubiquitin specific peptidase 7
6517 SLC2A4; solute carrier family 2 member 4
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
6789 STK4; serine/threonine kinase 4
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
6446 SGK1; serum/glucocorticoid regulated kinase 1
10110 SGK2; serum/glucocorticoid regulated kinase 2
23678 SGK3; serum/glucocorticoid regulated kinase family member 3
100533105 C8orf44-SGK3; C8orf44-SGK3 readthrough
2308 FOXO1; forkhead box O1
2309 FOXO3; forkhead box O3
4303 FOXO4; forkhead box O4
100132074 FOXO6; forkhead box O6
2911 GRM1; glutamate metabotropic receptor 1
9456 HOMER1; homer scaffold protein 1
9455 HOMER2; homer scaffold protein 2
9454 HOMER3; homer scaffold protein 3
116986 AGAP2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
1454 CSNK1E; casein kinase 1 epsilon
102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
3569 IL6; interleukin 6
3586 IL10; interleukin 10
6774 STAT3; signal transducer and activator of transcription 3
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
1017 CDK2; cyclin dependent kinase 2
3276 PRMT1; protein arginine methyltransferase 1
2290 FOXG1; forkhead box G1
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
85417 CCNB3; cyclin B3
595 CCND1; cyclin D1
894 CCND2; cyclin D2
901 CCNG2; cyclin G2
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1032 CDKN2D; cyclin dependent kinase inhibitor 2D
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
5934 RBL2; RB transcriptional corepressor like 2
5347 PLK1; polo like kinase 1
10769 PLK2; polo like kinase 2
1263 PLK3; polo like kinase 3
10733 PLK4; polo like kinase 4
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
356 FASLG; Fas ligand
10018 BCL2L11; BCL2 like 11
8743 TNFSF10; TNF superfamily member 10
604 BCL6; BCL6 transcription repressor
664 BNIP3; BCL2 interacting protein 3
9140 ATG12; autophagy related 12
11337 GABARAP; GABA type A receptor-associated protein
23710 GABARAPL1; GABA type A receptor associated protein like 1
11345 GABARAPL2; GABA type A receptor associated protein like 2
847 CAT; catalase
6648 SOD2; superoxide dismutase 2
472 ATM; ATM serine/threonine kinase
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
3575 IL7R; interleukin 7 receptor
10365 KLF2; Kruppel like factor 2
1901 S1PR1; sphingosine-1-phosphate receptor 1
8698 S1PR4; sphingosine-1-phosphate receptor 4
5896 RAG1; recombination activating 1
5897 RAG2; recombination activating 2
26260 FBXO25; F-box protein 25
114907 FBXO32; F-box protein 32
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
|
04020 Calcium signaling pathway [PATH:hsa04020]
|
04070 Phosphatidylinositol signaling system [PATH:hsa04070]
|
04072 Phospholipase D signaling pathway [PATH:hsa04072]
|
04071 Sphingolipid signaling pathway [PATH:hsa04071]
|
04024 cAMP signaling pathway [PATH:hsa04024]
|
04022 cGMP-PKG signaling pathway [PATH:hsa04022]
|
04151 PI3K-Akt signaling pathway [PATH:hsa04151]
|
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
2069 EREG; epiregulin
374 AREG; amphiregulin
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
4803 NGF; nerve growth factor
627 BDNF; brain derived neurotrophic factor
4908 NTF3; neurotrophin 3
4909 NTF4; neurotrophin 4
3630 INS; insulin
3479 IGF1; insulin like growth factor 1
3481 IGF2; insulin like growth factor 2
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1435 CSF1; colony stimulating factor 1
4254 KITLG; KIT ligand
2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
3082 HGF; hepatocyte growth factor
284 ANGPT1; angiopoietin 1
285 ANGPT2; angiopoietin 2
51378 ANGPT4; angiopoietin 4
1942 EFNA1; ephrin A1
1943 EFNA2; ephrin A2
1944 EFNA3; ephrin A3
1945 EFNA4; ephrin A4
1946 EFNA5; ephrin A5
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
2066 ERBB4; erb-b2 receptor tyrosine kinase 4
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
4804 NGFR; nerve growth factor receptor
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
4915 NTRK2; neurotrophic receptor tyrosine kinase 2
3643 INSR; insulin receptor
3480 IGF1R; insulin like growth factor 1 receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
1436 CSF1R; colony stimulating factor 1 receptor
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2322 FLT3; fms related receptor tyrosine kinase 3
2321 FLT1; fms related receptor tyrosine kinase 1
2324 FLT4; fms related receptor tyrosine kinase 4
3791 KDR; kinase insert domain receptor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
7010 TEK; TEK receptor tyrosine kinase
1969 EPHA2; EPH receptor A2
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3667 IRS1; insulin receptor substrate 1
7097 TLR2; toll like receptor 2
7099 TLR4; toll like receptor 4
5879 RAC1; Rac family small GTPase 1
102723407 IGH; immunoglobulin heavy variable 4-38-2-like
6850 SYK; spleen associated tyrosine kinase
930 CD19; CD19 molecule
118788 PIK3AP1; phosphoinositide-3-kinase adaptor protein 1
2688 GH1; growth hormone 1
2689 GH2; growth hormone 2
1442 CSH1; chorionic somatomammotropin hormone 1
1443 CSH2; chorionic somatomammotropin hormone 2
5617 PRL; prolactin
5008 OSM; oncostatin M
3558 IL2; interleukin 2
3562 IL3; interleukin 3
3569 IL6; interleukin 6
3565 IL4; interleukin 4
3574 IL7; interleukin 7
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
2056 EPO; erythropoietin
1440 CSF3; colony stimulating factor 3
2690 GHR; growth hormone receptor
5618 PRLR; prolactin receptor
9180 OSMR; oncostatin M receptor
3559 IL2RA; interleukin 2 receptor subunit alpha
3560 IL2RB; interleukin 2 receptor subunit beta
3561 IL2RG; interleukin 2 receptor subunit gamma
3563 IL3RA; interleukin 3 receptor subunit alpha
3570 IL6R; interleukin 6 receptor
3566 IL4R; interleukin 4 receptor
3575 IL7R; interleukin 7 receptor
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
2057 EPOR; erythropoietin receptor
1441 CSF3R; colony stimulating factor 3 receptor
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
1280 COL2A1; collagen type II alpha 1 chain
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
1291 COL6A1; collagen type VI alpha 1 chain
1292 COL6A2; collagen type VI alpha 2 chain
1293 COL6A3; collagen type VI alpha 3 chain
131873 COL6A6; collagen type VI alpha 6 chain
256076 COL6A5; collagen type VI alpha 5 chain
1297 COL9A1; collagen type IX alpha 1 chain
1298 COL9A2; collagen type IX alpha 2 chain
1299 COL9A3; collagen type IX alpha 3 chain
284217 LAMA1; laminin subunit alpha 1
3908 LAMA2; laminin subunit alpha 2
3909 LAMA3; laminin subunit alpha 3
3911 LAMA5; laminin subunit alpha 5
3910 LAMA4; laminin subunit alpha 4
3912 LAMB1; laminin subunit beta 1
3913 LAMB2; laminin subunit beta 2
3914 LAMB3; laminin subunit beta 3
22798 LAMB4; laminin subunit beta 4
3915 LAMC1; laminin subunit gamma 1
3918 LAMC2; laminin subunit gamma 2
10319 LAMC3; laminin subunit gamma 3
1101 CHAD; chondroadherin
5649 RELN; reelin
7057 THBS1; thrombospondin 1
1311 COMP; cartilage oligomeric matrix protein
7058 THBS2; thrombospondin 2
7059 THBS3; thrombospondin 3
7060 THBS4; thrombospondin 4
2335 FN1; fibronectin 1
6696 SPP1; secreted phosphoprotein 1
7448 VTN; vitronectin
3371 TNC; tenascin C
63923 TNN; tenascin N
7143 TNR; tenascin R
7148 TNXB; tenascin XB
7450 VWF; von Willebrand factor
3381 IBSP; integrin binding sialoprotein
3672 ITGA1; integrin subunit alpha 1
3673 ITGA2; integrin subunit alpha 2
3674 ITGA2B; integrin subunit alpha 2b
3675 ITGA3; integrin subunit alpha 3
3676 ITGA4; integrin subunit alpha 4
3678 ITGA5; integrin subunit alpha 5
3655 ITGA6; integrin subunit alpha 6
3679 ITGA7; integrin subunit alpha 7
8516 ITGA8; integrin subunit alpha 8
3680 ITGA9; integrin subunit alpha 9
8515 ITGA10; integrin subunit alpha 10
22801 ITGA11; integrin subunit alpha 11
3685 ITGAV; integrin subunit alpha V
3688 ITGB1; integrin subunit beta 1
3690 ITGB3; integrin subunit beta 3
3691 ITGB4; integrin subunit beta 4
3693 ITGB5; integrin subunit beta 5
3694 ITGB6; integrin subunit beta 6
3695 ITGB7; integrin subunit beta 7
3696 ITGB8; integrin subunit beta 8
5747 PTK2; protein tyrosine kinase 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
2149 F2R; coagulation factor II thrombin receptor
1128 CHRM1; cholinergic receptor muscarinic 1
1129 CHRM2; cholinergic receptor muscarinic 2
1902 LPAR1; lysophosphatidic acid receptor 1
9170 LPAR2; lysophosphatidic acid receptor 2
23566 LPAR3; lysophosphatidic acid receptor 3
2846 LPAR4; lysophosphatidic acid receptor 4
57121 LPAR5; lysophosphatidic acid receptor 5
10161 LPAR6; lysophosphatidic acid receptor 6
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
6794 STK11; serine/threonine kinase 11
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
54541 DDIT4; DNA damage inducible transcript 4
7248 TSC1; TSC complex subunit 1
7249 TSC2; TSC complex subunit 2
6009 RHEB; Ras homolog, mTORC1 binding
64223 MLST8; MTOR associated protein, LST8 homolog
2475 MTOR; mechanistic target of rapamycin kinase
57521 RPTOR; regulatory associated protein of MTOR complex 1
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
1977 EIF4E; eukaryotic translation initiation factor 4E
9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1975 EIF4B; eukaryotic translation initiation factor 4B
6194 RPS6; ribosomal protein S6
5578 PRKCA; protein kinase C alpha
5585 PKN1; protein kinase N1
5586 PKN2; protein kinase N2
29941 PKN3; protein kinase N3
6446 SGK1; serum/glucocorticoid regulated kinase 1
10110 SGK2; serum/glucocorticoid regulated kinase 2
23678 SGK3; serum/glucocorticoid regulated kinase family member 3
100533105 C8orf44-SGK3; C8orf44-SGK3 readthrough
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
9223 MAGI1; membrane associated guanylate kinase, WW and PDZ domain containing 1
9863 MAGI2; membrane associated guanylate kinase, WW and PDZ domain containing 2
5728 PTEN; phosphatase and tensin homolog
117145 THEM4; thioesterase superfamily member 4
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
28227 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta
55012 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma
5523 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha
5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
7184 HSP90B1; heat shock protein 90 beta family member 1
11140 CDC37; cell division cycle 37, HSP90 cochaperone
200186 CRTC2; CREB regulated transcription coactivator 2
23239 PHLPP1; PH domain and leucine rich repeat protein phosphatase 1
23035 PHLPP2; PH domain and leucine rich repeat protein phosphatase 2
8115 TCL1A; TCL1 family AKT coactivator A
9623 TCL1B; TCL1 family AKT coactivator B
4515 MTCP1; mature T cell proliferation 1
4846 NOS3; nitric oxide synthase 3
672 BRCA1; BRCA1 DNA repair associated
2932 GSK3B; glycogen synthase kinase 3 beta
2998 GYS2; glycogen synthase 2
2997 GYS1; glycogen synthase 1
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1017 CDK2; cyclin dependent kinase 2
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
894 CCND2; cyclin D2
896 CCND3; cyclin D3
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
2309 FOXO3; forkhead box O3
5934 RBL2; RB transcriptional corepressor like 2
356 FASLG; Fas ligand
10018 BCL2L11; BCL2 like 11
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
596 BCL2; BCL2 apoptosis regulator
842 CASP9; caspase 9
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
4170 MCL1; MCL1 apoptosis regulator, BCL2 family member
6256 RXRA; retinoid X receptor alpha
3164 NR4A1; nuclear receptor subfamily 4 group A member 1
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
5970 RELA; RELA proto-oncogene, NF-kB subunit
4790 NFKB1; nuclear factor kappa B subunit 1
4602 MYB; MYB proto-oncogene, transcription factor
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; B-lymphocyte antigen CD19
K12230 PIK3AP1; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05438 GH; growth hormone
K05438 GH; growth hormone
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05071 IL4R; interleukin 4 receptor
K05072 IL7R; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K03914 F2R; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K08270 DDIT4; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 MLST8; target of rapamycin complex subunit LST8
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e; small subunit ribosomal protein S6e
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05631 AIP3; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4; acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 RXRA; retinoid X receptor alpha
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB; transcriptional activator Myb
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
|
04152 AMPK signaling pathway [PATH:hsa04152]
|
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
6794 STK11; serine/threonine kinase 11
51719 CAB39; calcium binding protein 39
81617 CAB39L; calcium binding protein 39 like
92335 STRADA; STE20 related adaptor alpha
55437 STRADB; STE20 related adaptor beta
3952 LEP; leptin
3953 LEPR; leptin receptor
10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
148 ADRA1A; adrenoceptor alpha 1A
9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
51094 ADIPOR1; adiponectin receptor 1
79602 ADIPOR2; adiponectin receptor 2
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
5207 PFKFB1; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
5208 PFKFB2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
5209 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
5210 PFKFB4; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
2203 FBP1; fructose-bisphosphatase 1
8789 FBP2; fructose-bisphosphatase 2
5213 PFKM; phosphofructokinase, muscle
5214 PFKP; phosphofructokinase, platelet
5211 PFKL; phosphofructokinase, liver type
3172 HNF4A; hepatocyte nuclear factor 4 alpha
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
200186 CRTC2; CREB regulated transcription coactivator 2
1385 CREB1; cAMP responsive element binding protein 1
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
10891 PPARGC1A; PPARG coactivator 1 alpha
1994 ELAVL1; ELAV like RNA binding protein 1
595 CCND1; cyclin D1
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
29904 EEF2K; eukaryotic elongation factor 2 kinase
1938 EEF2; eukaryotic translation elongation factor 2
2308 FOXO1; forkhead box O1
2309 FOXO3; forkhead box O3
23411 SIRT1; sirtuin 1
6517 SLC2A4; solute carrier family 2 member 4
2998 GYS2; glycogen synthase 2
2997 GYS1; glycogen synthase 1
3991 LIPE; lipase E, hormone sensitive type
3156 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase
6720 SREBF1; sterol regulatory element binding transcription factor 1
2194 FASN; fatty acid synthase
31 ACACA; acetyl-CoA carboxylase alpha
6319 SCD; stearoyl-CoA desaturase
79966 SCD5; stearoyl-CoA desaturase 5
32 ACACB; acetyl-CoA carboxylase beta
23417 MLYCD; malonyl-CoA decarboxylase
1374 CPT1A; carnitine palmitoyltransferase 1A
1375 CPT1B; carnitine palmitoyltransferase 1B
126129 CPT1C; carnitine palmitoyltransferase 1C
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
28227 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta
55012 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma
5523 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha
5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
23216 TBC1D1; TBC1 domain family member 1
5862 RAB2A; RAB2A, member RAS oncogene family
4218 RAB8A; RAB8A, member RAS oncogene family
10890 RAB10; RAB10, member RAS oncogene family
9230 RAB11B; RAB11B, member RAS oncogene family
51552 RAB14; RAB14, member RAS oncogene family
1080 CFTR; CF transmembrane conductance regulator
948 CD36; CD36 molecule
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
7249 TSC2; TSC complex subunit 2
7248 TSC1; TSC complex subunit 1
6009 RHEB; Ras homolog, mTORC1 binding
2475 MTOR; mechanistic target of rapamycin kinase
57521 RPTOR; regulatory associated protein of MTOR complex 1
84335 AKT1S1; AKT1 substrate 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
5468 PPARG; peroxisome proliferator activated receptor gamma
8408 ULK1; unc-51 like autophagy activating kinase 1
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K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39; calcium binding protein 39
K08272 CAB39; calcium binding protein 39
K08271 STRADA; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K04135 ADRA1A; adrenergic receptor alpha-1A
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K19029 PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
K01103 PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
K19030 PFKFB4; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K07292 NR2A1; hepatocyte nuclear factor 4-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K13088 ELAVL1; ELAV-like protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K03234 EEF2; elongation factor 2
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K18341 TBC1D1; TBC1 domain family member 1
K07877 RAB2A; Ras-related protein Rab-2A
K07901 RAB8A; Ras-related protein Rab-8A
K07903 RAB10; Ras-related protein Rab-10
K07905 RAB11B; Ras-related protein Rab-11B
K07881 RAB14; Ras-related protein Rab-14
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K06259 CD36; CD36 antigen
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07207 TSC2; tuberous sclerosis 2
K07206 TSC1; tuberous sclerosis 1
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
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04150 mTOR signaling pathway [PATH:hsa04150]
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09141 Transport and catabolism
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09143 Cell growth and death
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04110 Cell cycle [PATH:hsa04110]
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595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
5933 RBL1; RB transcriptional corepressor like 1
5934 RBL2; RB transcriptional corepressor like 2
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
1874 E2F4; E2F transcription factor 4
1875 E2F5; E2F transcription factor 5
7027 TFDP1; transcription factor Dp-1
7029 TFDP2; transcription factor Dp-2
2932 GSK3B; glycogen synthase kinase 3 beta
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
4609 MYC; MYC proto-oncogene, bHLH transcription factor
7709 ZBTB17; zinc finger and BTB domain containing 17
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1031 CDKN2C; cyclin dependent kinase inhibitor 2C
1032 CDKN2D; cyclin dependent kinase inhibitor 2D
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1028 CDKN1C; cyclin dependent kinase inhibitor 1C
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
1017 CDK2; cyclin dependent kinase 2
6500 SKP1; S-phase kinase associated protein 1
8454 CUL1; cullin 1
9978 RBX1; ring-box 1
6502 SKP2; S-phase kinase associated protein 2
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
990 CDC6; cell division cycle 6
8318 CDC45; cell division cycle 45
8317 CDC7; cell division cycle 7
10926 DBF4; DBF4 zinc finger
983 CDK1; cyclin dependent kinase 1
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
85417 CCNB3; cyclin B3
994 CDC25B; cell division cycle 25B
995 CDC25C; cell division cycle 25C
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
5347 PLK1; polo like kinase 1
7465 WEE1; WEE1 G2 checkpoint kinase
494551 WEE2; WEE2 oocyte meiosis inhibiting kinase
9088 PKMYT1; protein kinase, membrane associated tyrosine/threonine 1
902 CCNH; cyclin H
1022 CDK7; cyclin dependent kinase 7
64682 ANAPC1; anaphase promoting complex subunit 1
29882 ANAPC2; anaphase promoting complex subunit 2
996 CDC27; cell division cycle 27
29945 ANAPC4; anaphase promoting complex subunit 4
51433 ANAPC5; anaphase promoting complex subunit 5
8881 CDC16; cell division cycle 16
51434 ANAPC7; anaphase promoting complex subunit 7
8697 CDC23; cell division cycle 23
10393 ANAPC10; anaphase promoting complex subunit 10
51529 ANAPC11; anaphase promoting complex subunit 11
246184 CDC26; cell division cycle 26
25847 ANAPC13; anaphase promoting complex subunit 13
991 CDC20; cell division cycle 20
9232 PTTG1; PTTG1 regulator of sister chromatid separation, securin
10744 PTTG2; pituitary tumor-transforming 2
9700 ESPL1; extra spindle pole bodies like 1, separase
8243 SMC1A; structural maintenance of chromosomes 1A
27127 SMC1B; structural maintenance of chromosomes 1B
9126 SMC3; structural maintenance of chromosomes 3
10735 STAG2; stromal antigen 2
10274 STAG1; stromal antigen 1
5885 RAD21; RAD21 cohesin complex component
7272 TTK; TTK protein kinase
699 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
9184 BUB3; BUB3 mitotic checkpoint protein
701 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
8379 MAD1L1; mitotic arrest deficient 1 like 1
4085 MAD2L1; mitotic arrest deficient 2 like 1
10459 MAD2L2; mitotic arrest deficient 2 like 2
51343 FZR1; fizzy and cell division cycle 20 related 1
8555 CDC14B; cell division cycle 14B
8556 CDC14A; cell division cycle 14A
545 ATR; ATR serine/threonine kinase
472 ATM; ATM serine/threonine kinase
7157 TP53; tumor protein p53
1111 CHEK1; checkpoint kinase 1
11200 CHEK2; checkpoint kinase 2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
5591 PRKDC; protein kinase, DNA-activated, catalytic subunit
4193 MDM2; MDM2 proto-oncogene
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
5111 PCNA; proliferating cell nuclear antigen
2810 SFN; stratifin
993 CDC25A; cell division cycle 25A
4998 ORC1; origin recognition complex subunit 1
4999 ORC2; origin recognition complex subunit 2
23595 ORC3; origin recognition complex subunit 3
5000 ORC4; origin recognition complex subunit 4
5001 ORC5; origin recognition complex subunit 5
23594 ORC6; origin recognition complex subunit 6
4171 MCM2; minichromosome maintenance complex component 2
4172 MCM3; minichromosome maintenance complex component 3
4173 MCM4; minichromosome maintenance complex component 4
4174 MCM5; minichromosome maintenance complex component 5
4175 MCM6; minichromosome maintenance complex component 6
4176 MCM7; minichromosome maintenance complex component 7
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K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K09993 CDKN1C; cyclin-dependent kinase inhibitor 1C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K06628 CDC45; cell division control protein 45
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 ASK; activator of S phase kinase
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06670 SCC1; cohesin complex subunit SCC1
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K06644 SFN; stratifin
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
|
04111 Cell cycle - yeast
|
04112 Cell cycle - Caulobacter
|
04113 Meiosis - yeast
|
04114 Oocyte meiosis [PATH:hsa04114]
|
04210 Apoptosis [PATH:hsa04210]
|
04214 Apoptosis - fly
|
04215 Apoptosis - multiple species [PATH:hsa04215]
|
04216 Ferroptosis [PATH:hsa04216]
|
04217 Necroptosis [PATH:hsa04217]
|
04115 p53 signaling pathway [PATH:hsa04115]
|
472 ATM; ATM serine/threonine kinase
11200 CHEK2; checkpoint kinase 2
545 ATR; ATR serine/threonine kinase
1111 CHEK1; checkpoint kinase 1
92344 GORAB; golgin, RAB6 interacting
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
4194 MDM4; MDM4 regulator of p53
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
1017 CDK2; cyclin dependent kinase 2
2810 SFN; stratifin
56475 RPRM; reprimo, TP53 dependent G2 arrest mediator homolog
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
983 CDK1; cyclin dependent kinase 1
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
51512 GTSE1; G2 and S-phase expressed 1
355 FAS; Fas cell surface death receptor
55367 PIDD1; p53-induced death domain protein 1
8797 TNFRSF10A; TNF receptor superfamily member 10a
8795 TNFRSF10B; TNF receptor superfamily member 10b
841 CASP8; caspase 8
637 BID; BH3 interacting domain death agonist
581 BAX; BCL2 associated X, apoptosis regulator
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
27113 BBC3; BCL2 binding component 3
63970 TP53AIP1; tumor protein p53 regulated apoptosis inducing protein 1
10572 SIVA1; SIVA1 apoptosis inducing factor
598 BCL2L1; BCL2 like 1
596 BCL2; BCL2 apoptosis regulator
9540 TP53I3; tumor protein p53 inducible protein 3
9538 EI24; EI24 autophagy associated transmembrane protein
51246 SHISA5; shisa family member 5
64065 PERP; p53 apoptosis effector related to PMP22
64393 ZMAT3; zinc finger matrin-type 3
6477 SIAH1; siah E3 ubiquitin protein ligase 1
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
842 CASP9; caspase 9
836 CASP3; caspase 3
84883 AIFM2; apoptosis inducing factor mitochondria associated 2
3486 IGFBP3; insulin like growth factor binding protein 3
3479 IGF1; insulin like growth factor 1
5054 SERPINE1; serpin family E member 1
575 ADGRB1; adhesion G protein-coupled receptor B1
3732 CD82; CD82 molecule
7057 THBS1; thrombospondin 1
5268 SERPINB5; serpin family B member 5
1643 DDB2; damage specific DNA binding protein 2
50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
6241 RRM2; ribonucleotide reductase regulatory subunit M2
27244 SESN1; sestrin 1
143686 SESN3; sestrin 3
83667 SESN2; sestrin 2
5728 PTEN; phosphatase and tensin homolog
7249 TSC2; TSC complex subunit 2
55240 STEAP3; STEAP3 metalloreductase
64326 COP1; COP1 E3 ubiquitin ligase
25898 RCHY1; ring finger and CHY zinc finger domain containing 1
900 CCNG1; cyclin G1
901 CCNG2; cyclin G2
8493 PPM1D; protein phosphatase, Mg2+/Mn2+ dependent 1D
7161 TP73; tumor protein p73
|
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K13773 TP53AIP1; p53-regulated apoptosis-inducing protein 1
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K04596 ADGRB1; adhesion G protein-coupled receptor B1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
|
04218 Cellular senescence [PATH:hsa04218]
|
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
5925 RB1; RB transcriptional corepressor 1
5933 RBL1; RB transcriptional corepressor like 1
5934 RBL2; RB transcriptional corepressor like 2
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
1874 E2F4; E2F transcription factor 4
1875 E2F5; E2F transcription factor 5
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
2308 FOXO1; forkhead box O1
2309 FOXO3; forkhead box O3
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
3105 HLA-A; major histocompatibility complex, class I, A
3106 HLA-B; major histocompatibility complex, class I, B
3107 HLA-C; major histocompatibility complex, class I, C
3134 HLA-F; major histocompatibility complex, class I, F
3135 HLA-G; major histocompatibility complex, class I, G
3133 HLA-E; major histocompatibility complex, class I, E
3805 KIR2DL4; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
3265 HRAS; HRas proto-oncogene, GTPase
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
7248 TSC1; TSC complex subunit 1
7249 TSC2; TSC complex subunit 2
6009 RHEB; Ras homolog, mTORC1 binding
2475 MTOR; mechanistic target of rapamycin kinase
5728 PTEN; phosphatase and tensin homolog
23411 SIRT1; sirtuin 1
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
4605 MYBL2; MYB proto-oncogene like 2
286826 LIN9; lin-9 DREAM MuvB core complex component
55957 LIN37; lin-37 DREAM MuvB core complex component
91750 LIN52; lin-52 DREAM MuvB core complex component
132660 LIN54; lin-54 DREAM MuvB core complex component
5928 RBBP4; RB binding protein 4, chromatin remodeling factor
2305 FOXM1; forkhead box M1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
83593 RASSF5; Ras association domain family member 5
8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
23291 FBXW11; F-box and WD repeat domain containing 11
10114 HIPK3; homeodomain interacting protein kinase 3
204851 HIPK1; homeodomain interacting protein kinase 1
28996 HIPK2; homeodomain interacting protein kinase 2
147746 HIPK4; homeodomain interacting protein kinase 4
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2113 ETS1; ETS proto-oncogene 1, transcription factor
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
983 CDK1; cyclin dependent kinase 1
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
85417 CCNB3; cyclin B3
4361 MRE11; MRE11 homolog, double strand break repair nuclease
10111 RAD50; RAD50 double strand break repair protein
4683 NBN; nibrin
472 ATM; ATM serine/threonine kinase
11200 CHEK2; checkpoint kinase 2
5883 RAD9A; RAD9 checkpoint clamp component A
144715 RAD9B; RAD9 checkpoint clamp component B
5810 RAD1; RAD1 checkpoint DNA exonuclease
3364 HUS1; HUS1 checkpoint clamp component
545 ATR; ATR serine/threonine kinase
1111 CHEK1; checkpoint kinase 1
993 CDC25A; cell division cycle 25A
8878 SQSTM1; sequestosome 1
2626 GATA4; GATA binding protein 4
10758 TRAF3IP2; TRAF3 interacting protein 2
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
3552 IL1A; interleukin 1 alpha
3569 IL6; interleukin 6
3576 CXCL8; C-X-C motif chemokine ligand 8
3486 IGFBP3; insulin like growth factor binding protein 3
5054 SERPINE1; serpin family E member 1
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
9261 MAPKAPK2; MAPK activated protein kinase 2
677 ZFP36L1; ZFP36 ring finger protein like 1
678 ZFP36L2; ZFP36 ring finger protein like 2
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
59341 TRPV4; transient receptor potential cation channel subfamily V member 4
54822 TRPM7; transient receptor potential cation channel subfamily M member 7
823 CAPN1; calpain 1
824 CAPN2; calpain 2
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
4776 NFATC4; nuclear factor of activated T cells 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
5481 PPID; peptidylprolyl isomerase D
7416 VDAC1; voltage dependent anion channel 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
90550 MCU; mitochondrial calcium uniporter
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K24231 KIR2DL4; killer cell immunoglobulin-like receptor 2DL4
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21769 MYBL2; myb-related protein B
K21773 LIN9; protein lin-9
K21774 LIN37; protein lin-37
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04383 IL1A; interleukin 1 alpha
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1; plasminogen activator inhibitor 1
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
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09144 Cellular community - eukaryotes
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04510 Focal adhesion [PATH:hsa04510]
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1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
1280 COL2A1; collagen type II alpha 1 chain
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
1291 COL6A1; collagen type VI alpha 1 chain
1292 COL6A2; collagen type VI alpha 2 chain
1293 COL6A3; collagen type VI alpha 3 chain
131873 COL6A6; collagen type VI alpha 6 chain
256076 COL6A5; collagen type VI alpha 5 chain
1297 COL9A1; collagen type IX alpha 1 chain
1298 COL9A2; collagen type IX alpha 2 chain
1299 COL9A3; collagen type IX alpha 3 chain
284217 LAMA1; laminin subunit alpha 1
3908 LAMA2; laminin subunit alpha 2
3909 LAMA3; laminin subunit alpha 3
3911 LAMA5; laminin subunit alpha 5
3910 LAMA4; laminin subunit alpha 4
3912 LAMB1; laminin subunit beta 1
3913 LAMB2; laminin subunit beta 2
3914 LAMB3; laminin subunit beta 3
22798 LAMB4; laminin subunit beta 4
3915 LAMC1; laminin subunit gamma 1
3918 LAMC2; laminin subunit gamma 2
10319 LAMC3; laminin subunit gamma 3
1101 CHAD; chondroadherin
5649 RELN; reelin
7057 THBS1; thrombospondin 1
1311 COMP; cartilage oligomeric matrix protein
7058 THBS2; thrombospondin 2
7059 THBS3; thrombospondin 3
7060 THBS4; thrombospondin 4
2335 FN1; fibronectin 1
6696 SPP1; secreted phosphoprotein 1
7448 VTN; vitronectin
3371 TNC; tenascin C
63923 TNN; tenascin N
7143 TNR; tenascin R
7148 TNXB; tenascin XB
7450 VWF; von Willebrand factor
3381 IBSP; integrin binding sialoprotein
3672 ITGA1; integrin subunit alpha 1
3673 ITGA2; integrin subunit alpha 2
3674 ITGA2B; integrin subunit alpha 2b
3675 ITGA3; integrin subunit alpha 3
3676 ITGA4; integrin subunit alpha 4
3678 ITGA5; integrin subunit alpha 5
3655 ITGA6; integrin subunit alpha 6
3679 ITGA7; integrin subunit alpha 7
8516 ITGA8; integrin subunit alpha 8
3680 ITGA9; integrin subunit alpha 9
8515 ITGA10; integrin subunit alpha 10
22801 ITGA11; integrin subunit alpha 11
3685 ITGAV; integrin subunit alpha V
3688 ITGB1; integrin subunit beta 1
3690 ITGB3; integrin subunit beta 3
3691 ITGB4; integrin subunit beta 4
3693 ITGB5; integrin subunit beta 5
3694 ITGB6; integrin subunit beta 6
3695 ITGB7; integrin subunit beta 7
3696 ITGB8; integrin subunit beta 8
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1950 EGF; epidermal growth factor
3479 IGF1; insulin like growth factor 1
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
3082 HGF; hepatocyte growth factor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3480 IGF1R; insulin like growth factor 1 receptor
3791 KDR; kinase insert domain receptor
1956 EGFR; epidermal growth factor receptor
2321 FLT1; fms related receptor tyrosine kinase 1
2324 FLT4; fms related receptor tyrosine kinase 4
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2909 ARHGAP35; Rho GTPase activating protein 35
394 ARHGAP5; Rho GTPase activating protein 5
387 RHOA; ras homolog family member A
1729 DIAPH1; diaphanous related formin 1
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
4633 MYL2; myosin light chain 2
4636 MYL5; myosin light chain 5
58498 MYL7; myosin light chain 7
10398 MYL9; myosin light chain 9
93408 MYL10; myosin light chain 10
103910 MYL12B; myosin light chain 12B
10627 MYL12A; myosin light chain 12A
29895 MYLPF; myosin light chain, phosphorylatable, fast skeletal muscle
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
23396 PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
8394 PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
8395 PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta
71 ACTG1; actin gamma 1
60 ACTB; actin beta
5923 RASGRF1; Ras protein specific guanine nucleotide releasing factor 1
824 CAPN2; calpain 2
87 ACTN1; actinin alpha 1
81 ACTN4; actinin alpha 4
7094 TLN1; talin 1
83660 TLN2; talin 2
2316 FLNA; filamin A
2318 FLNC; filamin C
2317 FLNB; filamin B
5829 PXN; paxillin
3611 ILK; integrin linked kinase
7791 ZYX; zyxin
7408 VASP; vasodilator stimulated phosphoprotein
7414 VCL; vinculin
29780 PARVB; parvin beta
55742 PARVA; parvin alpha
64098 PARVG; parvin gamma
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2932 GSK3B; glycogen synthase kinase 3 beta
1499 CTNNB1; catenin beta 1
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
5747 PTK2; protein tyrosine kinase 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5058 PAK1; p21 (RAC1) activated kinase 1
5062 PAK2; p21 (RAC1) activated kinase 2
5063 PAK3; p21 (RAC1) activated kinase 3
10298 PAK4; p21 (RAC1) activated kinase 4
57144 PAK5; p21 (RAC1) activated kinase 5
56924 PAK6; p21 (RAC1) activated kinase 6
106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
998 CDC42; cell division cycle 42
9564 BCAR1; BCAR1 scaffold protein, Cas family member
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
1793 DOCK1; dedicator of cytokinesis 1
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
5906 RAP1A; RAP1A, member of RAS oncogene family
5908 RAP1B; RAP1B, member of RAS oncogene family
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
857 CAV1; caveolin 1
858 CAV2; caveolin 2
859 CAV3; caveolin 3
2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2002 ELK1; ETS transcription factor ELK1
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
331 XIAP; X-linked inhibitor of apoptosis
572 BAD; BCL2 associated agonist of cell death
596 BCL2; BCL2 apoptosis regulator
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K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05732 ARHGAP35; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K06271 TLN; talin
K06271 TLN; talin
K04437 FLNA; filamin
K04437 FLNA; filamin
K04437 FLNA; filamin
K05760 PXN; paxillin
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06273 ZYX; zyxin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05700 VCL; vinculin
K06275 PARV; parvin
K06275 PARV; parvin
K06275 PARV; parvin
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
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04520 Adherens junction [PATH:hsa04520]
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04530 Tight junction [PATH:hsa04530]
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92359 CRB3; crumbs cell polarity complex component 3
1364 CLDN4; claudin 4
1365 CLDN3; claudin 3
1366 CLDN7; claudin 7
149461 CLDN19; claudin 19
10686 CLDN16; claudin 16
23562 CLDN14; claudin 14
24146 CLDN15; claudin 15
26285 CLDN17; claudin 17
49861 CLDN20; claudin 20
5010 CLDN11; claudin 11
51208 CLDN18; claudin 18
53842 CLDN22; claudin 22
7122 CLDN5; claudin 5
9071 CLDN10; claudin 10
9073 CLDN8; claudin 8
9074 CLDN6; claudin 6
9075 CLDN2; claudin 2
9076 CLDN1; claudin 1
9080 CLDN9; claudin 9
137075 CLDN23; claudin 23
100288814 CLDN34; claudin 34
644672 CLDN25; claudin 25
100132463 CLDN24; claudin 24
100506658 OCLN; occludin
50848 F11R; F11 receptor
58494 JAM2; junctional adhesion molecule 2
83700 JAM3; junctional adhesion molecule 3
11149 BVES; blood vessel epicardial substance
998 CDC42; cell division cycle 42
50855 PARD6A; par-6 family cell polarity regulator alpha
84552 PARD6G; par-6 family cell polarity regulator gamma
84612 PARD6B; par-6 family cell polarity regulator beta
64398 MPP5; membrane palmitoylated protein 5
58538 MPP4; membrane palmitoylated protein 4
27134 TJP3; tight junction protein 3
10207 PATJ; PATJ crumbs cell polarity complex component
8777 MPDZ; multiple PDZ domain crumbs cell polarity complex component
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
154796 AMOT; angiomotin
154810 AMOTL1; angiomotin like 1
51421 AMOTL2; angiomotin like 2
55114 ARHGAP17; Rho GTPase activating protein 17
5879 RAC1; Rac family small GTPase 1
4771 NF2; neurofibromin 2
3993 LLGL2; LLGL scribble cell polarity complex component 2
3996 LLGL1; LLGL scribble cell polarity complex component 1
1739 DLG1; discs large MAGUK scaffold protein 1
23513 SCRIB; scribble planar cell polarity protein
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
56288 PARD3; par-3 family cell polarity regulator
7074 TIAM1; TIAM Rac1 associated GEF 1
7082 TJP1; tight junction protein 1
93643 TJAP1; tight junction associated protein 1
1740 DLG2; discs large MAGUK scaffold protein 2
1741 DLG3; discs large MAGUK scaffold protein 3
4734 NEDD4; NEDD4 E3 ubiquitin protein ligase
23327 NEDD4L; NEDD4 like E3 ubiquitin protein ligase
57530 CGN; cingulin
84952 CGNL1; cingulin like 1
9181 ARHGEF2; Rho/Rac guanine nucleotide exchange factor 2
387 RHOA; ras homolog family member A
2626 GATA4; GATA binding protein 4
91862 MARVELD3; MARVEL domain containing 3
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
909 CD1A; CD1a molecule
910 CD1B; CD1b molecule
911 CD1C; CD1c molecule
912 CD1D; CD1d molecule
913 CD1E; CD1e molecule
1080 CFTR; CF transmembrane conductance regulator
1019 CDK4; cyclin dependent kinase 4
8531 YBX3; Y-box binding protein 3
8189 SYMPK; symplekin
5111 PCNA; proliferating cell nuclear antigen
595 CCND1; cyclin D1
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
861 RUNX1; RUNX family transcription factor 1
3308 HSPA4; heat shock protein family A (Hsp70) member 4
9368 SLC9A3R1; SLC9A3 regulator 1
7430 EZR; ezrin
5962 RDX; radixin
4478 MSN; moesin
5581 PRKCE; protein kinase C epsilon
71 ACTG1; actin gamma 1
60 ACTB; actin beta
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
5609 MAP2K7; mitogen-activated protein kinase kinase 7
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2017 CTTN; cortactin
3059 HCLS1; hematopoietic cell-specific Lyn substrate 1
10097 ACTR2; actin related protein 2
57180 ACTR3B; actin related protein 3B
653857 ACTR3C; actin related protein 3C
10096 ACTR3; actin related protein 3
10095 ARPC1B; actin related protein 2/3 complex subunit 1B
10552 ARPC1A; actin related protein 2/3 complex subunit 1A
10109 ARPC2; actin related protein 2/3 complex subunit 2
10094 ARPC3; actin related protein 2/3 complex subunit 3
10093 ARPC4; actin related protein 2/3 complex subunit 4
10092 ARPC5; actin related protein 2/3 complex subunit 5
81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
123720 WHAMM; WASP homolog associated with actin, golgi membranes and microtubules
7454 WAS; WASP actin nucleation promoting factor
7408 VASP; vasodilator stimulated phosphoprotein
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5872 RAB13; RAB13, member RAS oncogene family
23370 ARHGEF18; Rho/Rac guanine nucleotide exchange factor 18
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
4633 MYL2; myosin light chain 2
54566 EPB41L4B; erythrocyte membrane protein band 4.1 like 4B
6794 STK11; serine/threonine kinase 11
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
4627 MYH9; myosin heavy chain 9
4628 MYH10; myosin heavy chain 10
4629 MYH11; myosin heavy chain 11
79784 MYH14; myosin heavy chain 14
140465 MYL6B; myosin light chain 6B
4637 MYL6; myosin light chain 6
10398 MYL9; myosin light chain 9
103910 MYL12B; myosin light chain 12B
10627 MYL12A; myosin light chain 12A
150084 IGSF5; immunoglobulin superfamily member 5
9223 MAGI1; membrane associated guanylate kinase, WW and PDZ domain containing 1
11346 SYNPO; synaptopodin
87 ACTN1; actinin alpha 1
81 ACTN4; actinin alpha 4
79778 MICALL2; MICAL like 2
4218 RAB8A; RAB8A, member RAS oncogene family
51762 RAB8B; RAB8B, member RAS oncogene family
51735 RAPGEF6; Rap guanine nucleotide exchange factor 6
5906 RAP1A; RAP1A, member of RAS oncogene family
3688 ITGB1; integrin subunit beta 1
4301 AFDN; afadin, adherens junction formation factor
9414 TJP2; tight junction protein 2
9693 RAPGEF2; Rap guanine nucleotide exchange factor 2
57826 RAP2C; RAP2C, member of RAS oncogene family
153562 MARVELD2; MARVEL domain containing 2
10376 TUBA1B; tubulin alpha 1b
7277 TUBA4A; tubulin alpha 4a
7278 TUBA3C; tubulin alpha 3c
7846 TUBA1A; tubulin alpha 1a
84790 TUBA1C; tubulin alpha 1c
51807 TUBA8; tubulin alpha 8
112714 TUBA3E; tubulin alpha 3e
113457 TUBA3D; tubulin alpha 3d
79861 TUBAL3; tubulin alpha like 3
|
K06090 CRB3; crumbs 3
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06087 CLDN; claudin
K06088 OCLN; occludin
K06089 F11R; junctional adhesion molecule 1
K06735 JAM2; junctional adhesion molecule 2
K06785 JAM3; junctional adhesion molecule 3
K21108 BVES; blood vessel epicardial substance
K04393 CDC42; cell division control protein 42
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06091 MPP5; MAGUK p55 subfamily member 5
K21109 MPP4; MAGUK p55 subfamily member 4
K06097 TJP3; tight junction protein 3
K06092 INADL; InaD-like protein
K06095 MPDZ; multiple PDZ domain protein
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K16819 AMOT; angiomotin
K06104 AMOTL; angiomotin like
K06104 AMOTL; angiomotin like
K20638 ARHGAP17; Rho GTPase-activating protein 17
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16684 NF2; merlin
K06094 LLGL; lethal(2) giant larvae protein
K06094 LLGL; lethal(2) giant larvae protein
K12076 DLG1; disks large protein 1
K16175 SCRIB; protein scribble
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04237 PARD3; partitioning defective protein 3
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K05701 TJP1; tight junction protein 1
K06105 TJP4; tight junction protein 4
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
K06102 CGN; cingulin
K21110 CGNL1; cingulin-like protein 1
K12791 ARHGEF2; Rho guanine nucleotide exchange factor 2
K04513 RHOA; Ras homolog gene family, member A
K09183 GATA4; GATA-binding protein 4
K21099 MARVELD3; MARVEL domain-containing protein 3
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K06448 CD1; T-cell surface glycoprotein CD1
K06448 CD1; T-cell surface glycoprotein CD1
K06448 CD1; T-cell surface glycoprotein CD1
K06448 CD1; T-cell surface glycoprotein CD1
K06448 CD1; T-cell surface glycoprotein CD1
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06099 CSDA; cold shock domain protein A
K06100 SYMPK; symplekin
K04802 PCNA; proliferating cell nuclear antigen
K04503 CCND1; G1/S-specific cyclin-D1
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K08367 RUNX1; runt-related transcription factor 1
K09489 HSPA4; heat shock 70kDa protein 4
K13365 SLC9A3R1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
K08007 VIL2; villin 2 (ezrin)
K05762 RDX; radixin
K05763 MSN; moesin
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06106 CTTN; cortactin
K06106 CTTN; cortactin
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K20479 WHAMM; WASP homolog-associated protein with actin, membranes and microtubules
K05747 WAS; Wiskott-Aldrich syndrome protein
K06274 VASP; vasodilator-stimulated phosphoprotein
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K06109 RAB13; Ras-related protein Rab-13
K21066 ARHGEF18; A-kinase anchor protein 18
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K21111 EPB41L4B; band 4.1-like protein 4B
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K10352 MYH9s; myosin heavy chain 9/10/11/14
K12751 MYL6; myosin light chain 6
K12751 MYL6; myosin light chain 6
K12755 MYL9; myosin regulatory light chain 9
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K06786 JAM4; junctional adhesion molecule 4
K05631 AIP3; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K21112 SYNPO; synaptopodin
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K21068 MICALL2; MICAL-like protein 2
K07901 RAB8A; Ras-related protein Rab-8A
K07902 RAB8B; Ras-related protein Rab-8B
K08020 RAPGEF6; Rap guanine nucleotide exchange factor 6
K04353 RAP1A; Ras-related protein Rap-1A
K05719 ITGB1; integrin beta 1
K05702 AF6; afadin
K06098 TJP2; tight junction protein 2
K08018 RAPGEF2; Rap guanine nucleotide exchange factor 2
K07839 RAP2C; Ras-related protein Rap-2C
K17291 MARVELD2; MARVEL domain-containing protein 2
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
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04540 Gap junction [PATH:hsa04540]
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04550 Signaling pathways regulating pluripotency of stem cells [PATH:hsa04550]
|
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09145 Cellular community - prokaryotes
|
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09142 Cell motility
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09150 Organismal Systems
|
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09151 Immune system
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09152 Endocrine system
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04911 Insulin secretion [PATH:hsa04911]
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04910 Insulin signaling pathway [PATH:hsa04910]
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04922 Glucagon signaling pathway [PATH:hsa04922]
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04923 Regulation of lipolysis in adipocytes [PATH:hsa04923]
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04920 Adipocytokine signaling pathway [PATH:hsa04920]
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03320 PPAR signaling pathway [PATH:hsa03320]
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04929 GnRH secretion [PATH:hsa04929]
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04912 GnRH signaling pathway [PATH:hsa04912]
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04913 Ovarian steroidogenesis [PATH:hsa04913]
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04915 Estrogen signaling pathway [PATH:hsa04915]
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04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
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04917 Prolactin signaling pathway [PATH:hsa04917]
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5617 PRL; prolactin
5618 PRLR; prolactin receptor
3717 JAK2; Janus kinase 2
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2309 FOXO3; forkhead box O3
2592 GALT; galactose-1-phosphate uridylyltransferase
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
595 CCND1; cyclin D1
2932 GSK3B; glycogen synthase kinase 3 beta
1154 CISH; cytokine inducible SH2 containing protein
8651 SOCS1; suppressor of cytokine signaling 1
8835 SOCS2; suppressor of cytokine signaling 2
9021 SOCS3; suppressor of cytokine signaling 3
122809 SOCS4; suppressor of cytokine signaling 4
9655 SOCS5; suppressor of cytokine signaling 5
30837 SOCS7; suppressor of cytokine signaling 7
9306 SOCS6; suppressor of cytokine signaling 6
6772 STAT1; signal transducer and activator of transcription 1
6774 STAT3; signal transducer and activator of transcription 3
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
8600 TNFSF11; TNF superfamily member 11
8792 TNFRSF11A; TNF receptor superfamily member 11a
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
2001 ELF5; E74 like ETS transcription factor 5
1447 CSN2; casein beta
1081 CGA; glycoprotein hormones, alpha polypeptide
3972 LHB; luteinizing hormone subunit beta
3973 LHCGR; luteinizing hormone/choriogonadotropin receptor
1586 CYP17A1; cytochrome P450 family 17 subfamily A member 1
2099 ESR1; estrogen receptor 1
2100 ESR2; estrogen receptor 2
3659 IRF1; interferon regulatory factor 1
7054 TH; tyrosine hydroxylase
6514 SLC2A2; solute carrier family 2 member 2
2645 GCK; glucokinase
894 CCND2; cyclin D2
3630 INS; insulin
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K05439 PRL; prolactin
K05081 PRLR; prolactin receptor
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04503 CCND1; G1/S-specific cyclin-D1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04701 CISH; cytokine inducible SH2-containing protein
K04694 SOCS1; suppressor of cytokine signaling 1
K04695 SOCS2; suppressor of cytokine signaling 2
K04696 SOCS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K04698 SOCS5; suppressor of cytokine signaling 5
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K11220 STAT1; signal transducer and activator of transcription 1
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A; tumor necrosis factor receptor superfamily member 11A
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K17101 ELF5; E74-like factor 5
K17107 CSN2; beta-casein
K08522 CGA; glycoprotein hormones alpha chain
K08521 LHB; lutropin subunit beta
K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09444 IRF1; interferon regulatory factor 1
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K10151 CCND2; G1/S-specific cyclin-D2
K04526 INS; insulin
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04921 Oxytocin signaling pathway [PATH:hsa04921]
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5020 OXT; oxytocin/neurophysin I prepropeptide
5021 OXTR; oxytocin receptor
2776 GNAQ; G protein subunit alpha q
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
123745 PLA2G4E; phospholipase A2 group IVE
5321 PLA2G4A; phospholipase A2 group IVA
8681 JMJD7-PLA2G4B; JMJD7-PLA2G4B readthrough
100137049 PLA2G4B; phospholipase A2 group IVB
8605 PLA2G4C; phospholipase A2 group IVC
283748 PLA2G4D; phospholipase A2 group IVD
255189 PLA2G4F; phospholipase A2 group IVF
5743 PTGS2; prostaglandin-endoperoxide synthase 2
5607 MAP2K5; mitogen-activated protein kinase kinase 5
5598 MAPK7; mitogen-activated protein kinase 7
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
4208 MEF2C; myocyte enhancer factor 2C
595 CCND1; cyclin D1
2002 ELK1; ETS transcription factor ELK1
6261 RYR1; ryanodine receptor 1
6262 RYR2; ryanodine receptor 2
6263 RYR3; ryanodine receptor 3
952 CD38; CD38 molecule
7226 TRPM2; transient receptor potential cation channel subfamily M member 2
3759 KCNJ2; potassium inwardly rectifying channel subfamily J member 2
3768 KCNJ12; potassium inwardly rectifying channel subfamily J member 12
100134444 KCNJ18; potassium inwardly rectifying channel subfamily J member 18
3761 KCNJ4; potassium inwardly rectifying channel subfamily J member 4
3770 KCNJ14; potassium inwardly rectifying channel subfamily J member 14
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
29904 EEF2K; eukaryotic elongation factor 2 kinase
1938 EEF2; eukaryotic translation elongation factor 2
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
782 CACNB1; calcium voltage-gated channel auxiliary subunit beta 1
783 CACNB2; calcium voltage-gated channel auxiliary subunit beta 2
784 CACNB3; calcium voltage-gated channel auxiliary subunit beta 3
785 CACNB4; calcium voltage-gated channel auxiliary subunit beta 4
781 CACNA2D1; calcium voltage-gated channel auxiliary subunit alpha2delta 1
9254 CACNA2D2; calcium voltage-gated channel auxiliary subunit alpha2delta 2
55799 CACNA2D3; calcium voltage-gated channel auxiliary subunit alpha2delta 3
93589 CACNA2D4; calcium voltage-gated channel auxiliary subunit alpha2delta 4
786 CACNG1; calcium voltage-gated channel auxiliary subunit gamma 1
10369 CACNG2; calcium voltage-gated channel auxiliary subunit gamma 2
10368 CACNG3; calcium voltage-gated channel auxiliary subunit gamma 3
27092 CACNG4; calcium voltage-gated channel auxiliary subunit gamma 4
27091 CACNG5; calcium voltage-gated channel auxiliary subunit gamma 5
59285 CACNG6; calcium voltage-gated channel auxiliary subunit gamma 6
59284 CACNG7; calcium voltage-gated channel auxiliary subunit gamma 7
59283 CACNG8; calcium voltage-gated channel auxiliary subunit gamma 8
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
4776 NFATC4; nuclear factor of activated T cells 4
5997 RGS2; regulator of G protein signaling 2
1827 RCAN1; regulator of calcineurin 1
10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
57118 CAMK1D; calcium/calmodulin dependent protein kinase ID
57172 CAMK1G; calcium/calmodulin dependent protein kinase IG
8536 CAMK1; calcium/calmodulin dependent protein kinase I
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
814 CAMK4; calcium/calmodulin dependent protein kinase IV
4846 NOS3; nitric oxide synthase 3
2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
4878 NPPA; natriuretic peptide A
4881 NPR1; natriuretic peptide receptor 1
4882 NPR2; natriuretic peptide receptor 2
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
140465 MYL6B; myosin light chain 6B
4637 MYL6; myosin light chain 6
10398 MYL9; myosin light chain 9
71 ACTG1; actin gamma 1
60 ACTB; actin beta
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2775 GNAO1; G protein subunit alpha o1
5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
3760 KCNJ3; potassium inwardly rectifying channel subfamily J member 3
3763 KCNJ6; potassium inwardly rectifying channel subfamily J member 6
3765 KCNJ9; potassium inwardly rectifying channel subfamily J member 9
3762 KCNJ5; potassium inwardly rectifying channel subfamily J member 5
1956 EGFR; epidermal growth factor receptor
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
|
K05243 OXT; oxytocin-neurophysin 1
K04229 OXTR; oxytocin receptor
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K04503 CCND1; G1/S-specific cyclin-D1
K04375 ELK1; ETS domain-containing protein Elk-1
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K04977 TRPM2; transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
K04996 KCNJ2; potassium inwardly-rectifying channel subfamily J member 2
K05005 KCNJ12_18; potassium inwardly-rectifying channel subfamily J member 12/18
K05005 KCNJ12_18; potassium inwardly-rectifying channel subfamily J member 12/18
K04998 KCNJ4; potassium inwardly-rectifying channel subfamily J member 4
K05007 KCNJ14; potassium inwardly-rectifying channel subfamily J member 14
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K03234 EEF2; elongation factor 2
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K18154 RGS2; regulator of G-protein signaling 2
K17901 RCAN1; calcipressin-1
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12334 NPPA; natriuretic peptide A
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12751 MYL6; myosin light chain 6
K12751 MYL6; myosin light chain 6
K12755 MYL9; myosin regulatory light chain 9
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
|
04926 Relaxin signaling pathway [PATH:hsa04926]
|
04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
|
04918 Thyroid hormone synthesis [PATH:hsa04918]
|
04919 Thyroid hormone signaling pathway [PATH:hsa04919]
|
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
3685 ITGAV; integrin subunit alpha V
3690 ITGB3; integrin subunit beta 3
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6772 STAT1; signal transducer and activator of transcription 1
7157 TP53; tumor protein p53
2099 ESR1; estrogen receptor 1
7068 THRB; thyroid hormone receptor beta
9611 NCOR1; nuclear receptor corepressor 1
25942 SIN3A; SIN3 transcription regulator family member A
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
8841 HDAC3; histone deacetylase 3
7067 THRA; thyroid hormone receptor alpha
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
8850 KAT2B; lysine acetyltransferase 2B
2648 KAT2A; lysine acetyltransferase 2A
8648 NCOA1; nuclear receptor coactivator 1
10499 NCOA2; nuclear receptor coactivator 2
8202 NCOA3; nuclear receptor coactivator 3
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
29079 MED4; mediator complex subunit 4
116931 MED12L; mediator complex subunit 12L
9968 MED12; mediator complex subunit 12
23389 MED13L; mediator complex subunit 13L
9969 MED13; mediator complex subunit 13
9282 MED14; mediator complex subunit 14
10025 MED16; mediator complex subunit 16
9440 MED17; mediator complex subunit 17
9862 MED24; mediator complex subunit 24
9442 MED27; mediator complex subunit 27
90390 MED30; mediator complex subunit 30
5469 MED1; mediator complex subunit 1
595 CCND1; cyclin D1
2626 GATA4; GATA binding protein 4
1827 RCAN1; regulator of calcineurin 1
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
4609 MYC; MYC proto-oncogene, bHLH transcription factor
4625 MYH7; myosin heavy chain 7
4624 MYH6; myosin heavy chain 6
487 ATP2A1; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
489 ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
488 ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
5350 PLN; phospholamban
54361 WNT4; Wnt family member 4
1499 CTNNB1; catenin beta 1
4851 NOTCH1; notch receptor 1
4853 NOTCH2; notch receptor 2
4854 NOTCH3; notch receptor 3
4855 NOTCH4; notch receptor 4
652 BMP4; bone morphogenetic protein 4
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5333 PLCD1; phospholipase C delta 1
113026 PLCD3; phospholipase C delta 3
84812 PLCD4; phospholipase C delta 4
51196 PLCE1; phospholipase C epsilon 1
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
89869 PLCZ1; phospholipase C zeta 1
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
6548 SLC9A1; solute carrier family 9 member A1
476 ATP1A1; ATPase Na+/K+ transporting subunit alpha 1
477 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2
478 ATP1A3; ATPase Na+/K+ transporting subunit alpha 3
480 ATP1A4; ATPase Na+/K+ transporting subunit alpha 4
23439 ATP1B4; ATPase Na+/K+ transporting family member beta 4
481 ATP1B1; ATPase Na+/K+ transporting subunit beta 1
482 ATP1B2; ATPase Na+/K+ transporting subunit beta 2
483 ATP1B3; ATPase Na+/K+ transporting subunit beta 3
486 FXYD2; FXYD domain containing ion transport regulator 2
6567 SLC16A2; solute carrier family 16 member 2
117247 SLC16A10; solute carrier family 16 member 10
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2932 GSK3B; glycogen synthase kinase 3 beta
4193 MDM2; MDM2 proto-oncogene
7249 TSC2; TSC complex subunit 2
6009 RHEB; Ras homolog, mTORC1 binding
2475 MTOR; mechanistic target of rapamycin kinase
9882 TBC1D4; TBC1 domain family member 4
5208 PFKFB2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
572 BAD; BCL2 associated agonist of cell death
2308 FOXO1; forkhead box O1
842 CASP9; caspase 9
10231 RCAN2; regulator of calcineurin 2
6513 SLC2A1; solute carrier family 2 member 1
5213 PFKM; phosphofructokinase, muscle
5214 PFKP; phosphofructokinase, platelet
5211 PFKL; phosphofructokinase, liver type
53919 SLCO1C1; solute carrier organic anion transporter family member 1C1
1733 DIO1; iodothyronine deiodinase 1
1734 DIO2; iodothyronine deiodinase 2
1735 DIO3; iodothyronine deiodinase 3
71 ACTG1; actin gamma 1
60 ACTB; actin beta
|
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K06487 ITGAV; integrin alpha V
K06493 ITGB3; integrin beta 3
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K11220 STAT1; signal transducer and activator of transcription 1
K04451 TP53; tumor protein p53
K08550 ESR1; estrogen receptor alpha
K08362 THRB; thyroid hormone receptor beta
K04650 NCOR1; nuclear receptor co-repressor 1
K11644 SIN3A; paired amphipathic helix protein Sin3a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K05547 THRA; thyroid hormone receptor alpha
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11255 NCOA2; nuclear receptor coactivator 2
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K15146 MED4; mediator of RNA polymerase II transcription subunit 4
K15162 MED12; mediator of RNA polymerase II transcription subunit 12
K15162 MED12; mediator of RNA polymerase II transcription subunit 12
K15164 MED13; mediator of RNA polymerase II transcription subunit 13
K15164 MED13; mediator of RNA polymerase II transcription subunit 13
K15156 MED14; mediator of RNA polymerase II transcription subunit 14
K15159 MED16; mediator of RNA polymerase II transcription subunit 16
K15133 MED17; mediator of RNA polymerase II transcription subunit 17
K15167 MED24; mediator of RNA polymerase II transcription subunit 24
K15170 MED27; mediator of RNA polymerase II transcription subunit 27
K15143 MED30; mediator of RNA polymerase II transcription subunit 30
K15144 MED1; mediator of RNA polymerase II transcription subunit 1
K04503 CCND1; G1/S-specific cyclin-D1
K09183 GATA4; GATA-binding protein 4
K17901 RCAN1; calcipressin-1
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04377 MYC; Myc proto-oncogene protein
K17751 MYH6_7; myosin heavy chain 6/7
K17751 MYH6_7; myosin heavy chain 6/7
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05852 PLN; phospholamban
K00408 WNT4; wingless-type MMTV integration site family, member 4
K02105 CTNNB1; catenin beta 1
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K04662 BMP4; bone morphogenetic protein 4
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K08231 SLC16A2; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 2
K08187 SLC16A10; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 10
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K17902 TBC1D4; TBC1 domain family member 4
K19029 PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K17903 RCAN2; calcipressin-2
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K08747 SLCO1C; solute carrier organic anion transporter family, member 1C
K01562 DIO1; type I thyroxine 5'-deiodinase [EC:1.21.99.4]
K17904 DIO2; type II thyroxine 5'-deiodinase [EC:1.21.99.4]
K07754 DIO3; thyroxine 5-deiodinase [EC:1.21.99.3]
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
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04928 Parathyroid hormone synthesis, secretion and action [PATH:hsa04928]
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04916 Melanogenesis [PATH:hsa04916]
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04924 Renin secretion [PATH:hsa04924]
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04614 Renin-angiotensin system [PATH:hsa04614]
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04925 Aldosterone synthesis and secretion [PATH:hsa04925]
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04927 Cortisol synthesis and secretion [PATH:hsa04927]
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:hsa05200]
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1630 DCC; DCC netrin 1 receptor
836 CASP3; caspase 3
842 CASP9; caspase 9
26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
999 CDH1; cadherin 1
1499 CTNNB1; catenin beta 1
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
332 BIRC5; baculoviral IAP repeat containing 5
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2147 F2; coagulation factor II, thrombin
183 AGT; angiotensinogen
2149 F2R; coagulation factor II thrombin receptor
9002 F2RL3; F2R like thrombin or trypsin receptor 3
1902 LPAR1; lysophosphatidic acid receptor 1
9170 LPAR2; lysophosphatidic acid receptor 2
23566 LPAR3; lysophosphatidic acid receptor 3
2846 LPAR4; lysophosphatidic acid receptor 4
57121 LPAR5; lysophosphatidic acid receptor 5
10161 LPAR6; lysophosphatidic acid receptor 6
185 AGTR1; angiotensin II receptor type 1
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
57449 PLEKHG5; pleckstrin homology and RhoGEF domain containing G5
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
6387 CXCL12; C-X-C motif chemokine ligand 12
7852 CXCR4; C-X-C motif chemokine receptor 4
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
5731 PTGER1; prostaglandin E receptor 1
5732 PTGER2; prostaglandin E receptor 2
5733 PTGER3; prostaglandin E receptor 3
5734 PTGER4; prostaglandin E receptor 4
2778 GNAS; GNAS complex locus
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
2782 GNB1; G protein subunit beta 1
2783 GNB2; G protein subunit beta 2
2784 GNB3; G protein subunit beta 3
59345 GNB4; G protein subunit beta 4
10681 GNB5; G protein subunit beta 5
54331 GNG2; G protein subunit gamma 2
2785 GNG3; G protein subunit gamma 3
2786 GNG4; G protein subunit gamma 4
2787 GNG5; G protein subunit gamma 5
2788 GNG7; G protein subunit gamma 7
94235 GNG8; G protein subunit gamma 8
2790 GNG10; G protein subunit gamma 10
2791 GNG11; G protein subunit gamma 11
55970 GNG12; G protein subunit gamma 12
51764 GNG13; G protein subunit gamma 13
2792 GNGT1; G protein subunit gamma transducin 1
2793 GNGT2; G protein subunit gamma transducin 2
1284 COL4A2; collagen type IV alpha 2 chain
1286 COL4A4; collagen type IV alpha 4 chain
1288 COL4A6; collagen type IV alpha 6 chain
1282 COL4A1; collagen type IV alpha 1 chain
1287 COL4A5; collagen type IV alpha 5 chain
1285 COL4A3; collagen type IV alpha 3 chain
284217 LAMA1; laminin subunit alpha 1
3908 LAMA2; laminin subunit alpha 2
3909 LAMA3; laminin subunit alpha 3
3911 LAMA5; laminin subunit alpha 5
3910 LAMA4; laminin subunit alpha 4
3912 LAMB1; laminin subunit beta 1
3913 LAMB2; laminin subunit beta 2
3914 LAMB3; laminin subunit beta 3
22798 LAMB4; laminin subunit beta 4
3915 LAMC1; laminin subunit gamma 1
3918 LAMC2; laminin subunit gamma 2
10319 LAMC3; laminin subunit gamma 3
2335 FN1; fibronectin 1
3673 ITGA2; integrin subunit alpha 2
3674 ITGA2B; integrin subunit alpha 2b
3675 ITGA3; integrin subunit alpha 3
3655 ITGA6; integrin subunit alpha 6
3685 ITGAV; integrin subunit alpha V
3688 ITGB1; integrin subunit beta 1
5747 PTK2; protein tyrosine kinase 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
4824 NKX3-1; NK3 homeobox 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
4791 NFKB2; nuclear factor kappa B subunit 2
5970 RELA; RELA proto-oncogene, NF-kB subunit
5743 PTGS2; prostaglandin-endoperoxide synthase 2
4843 NOS2; nitric oxide synthase 2
596 BCL2; BCL2 apoptosis regulator
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
331 XIAP; X-linked inhibitor of apoptosis
79444 BIRC7; baculoviral IAP repeat containing 7
598 BCL2L1; BCL2 like 1
7185 TRAF1; TNF receptor associated factor 1
7186 TRAF2; TNF receptor associated factor 2
7187 TRAF3; TNF receptor associated factor 3
9618 TRAF4; TNF receptor associated factor 4
7188 TRAF5; TNF receptor associated factor 5
7189 TRAF6; TNF receptor associated factor 6
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
572 BAD; BCL2 associated agonist of cell death
2308 FOXO1; forkhead box O1
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
613 BCR; BCR activator of RhoGEF and GTPase
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
867 CBL; Cbl proto-oncogene
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
3827 KNG1; kininogen 1
1906 EDN1; endothelin 1
623 BDKRB1; bradykinin receptor B1
624 BDKRB2; bradykinin receptor B2
1909 EDNRA; endothelin receptor type A
1910 EDNRB; endothelin receptor type B
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
3558 IL2; interleukin 2
3562 IL3; interleukin 3
3565 IL4; interleukin 4
3567 IL5; interleukin 5
3569 IL6; interleukin 6
3574 IL7; interleukin 7
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3596 IL13; interleukin 13
3600 IL15; interleukin 15
51561 IL23A; interleukin 23 subunit alpha
2056 EPO; erythropoietin
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3458 IFNG; interferon gamma
3559 IL2RA; interleukin 2 receptor subunit alpha
3560 IL2RB; interleukin 2 receptor subunit beta
3561 IL2RG; interleukin 2 receptor subunit gamma
3563 IL3RA; interleukin 3 receptor subunit alpha
3566 IL4R; interleukin 4 receptor
1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
3568 IL5RA; interleukin 5 receptor subunit alpha
3570 IL6R; interleukin 6 receptor
3572 IL6ST; interleukin 6 signal transducer
3575 IL7R; interleukin 7 receptor
3594 IL12RB1; interleukin 12 receptor subunit beta 1
3595 IL12RB2; interleukin 12 receptor subunit beta 2
3597 IL13RA1; interleukin 13 receptor subunit alpha 1
3601 IL15RA; interleukin 15 receptor subunit alpha
149233 IL23R; interleukin 23 receptor
2057 EPOR; erythropoietin receptor
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
27436 EML4; EMAP like 4
238 ALK; ALK receptor tyrosine kinase
10125 RASGRP1; RAS guanyl releasing protein 1
10235 RASGRP2; RAS guanyl releasing protein 2
25780 RASGRP3; RAS guanyl releasing protein 3
115727 RASGRP4; RAS guanyl releasing protein 4
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
3718 JAK3; Janus kinase 3
6774 STAT3; signal transducer and activator of transcription 3
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
6775 STAT4; signal transducer and activator of transcription 4
6778 STAT6; signal transducer and activator of transcription 6
7422 VEGFA; vascular endothelial growth factor A
7423 VEGFB; vascular endothelial growth factor B
5228 PGF; placental growth factor
7424 VEGFC; vascular endothelial growth factor C
2277 VEGFD; vascular endothelial growth factor D
7039 TGFA; transforming growth factor alpha
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3479 IGF1; insulin like growth factor 1
3481 IGF2; insulin like growth factor 2
3480 IGF1R; insulin like growth factor 1 receptor
4254 KITLG; KIT ligand
3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
2322 FLT3; fms related receptor tyrosine kinase 3
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
2261 FGFR3; fibroblast growth factor receptor 3
2264 FGFR4; fibroblast growth factor receptor 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
2113 ETS1; ETS proto-oncogene 1, transcription factor
4312 MMP1; matrix metallopeptidase 1
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
3576 CXCL8; C-X-C motif chemokine ligand 8
1019 CDK4; cyclin dependent kinase 4
9252 RPS6KA5; ribosomal protein S6 kinase A5
5979 RET; ret proto-oncogene
8030 CCDC6; coiled-coil domain containing 6
8031 NCOA4; nuclear receptor coactivator 4
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
7170 TPM3; tropomyosin 3
7175 TPR; translocated promoter region, nuclear basket protein
10342 TFG; trafficking from ER to golgi regulator
11186 RASSF1; Ras association domain family member 1
83593 RASSF5; Ras association domain family member 5
6789 STK4; serine/threonine kinase 4
1612 DAPK1; death associated protein kinase 1
1613 DAPK3; death associated protein kinase 3
23604 DAPK2; death associated protein kinase 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
2002 ELK1; ETS transcription factor ELK1
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
10928 RALBP1; ralA binding protein 1
998 CDC42; cell division cycle 42
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
7849 PAX8; paired box 8
5468 PPARG; peroxisome proliferator activated receptor gamma
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
5915 RARB; retinoic acid receptor beta
2099 ESR1; estrogen receptor 1
2100 ESR2; estrogen receptor 2
8648 NCOA1; nuclear receptor coactivator 1
8202 NCOA3; nuclear receptor coactivator 3
6667 SP1; Sp1 transcription factor
5467 PPARD; peroxisome proliferator activated receptor delta
3728 JUP; junction plakoglobin
7704 ZBTB16; zinc finger and BTB domain containing 16
5914 RARA; retinoic acid receptor alpha
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
5371 PML; PML nuclear body scaffold
861 RUNX1; RUNX family transcription factor 1
862 RUNX1T1; RUNX1 partner transcriptional co-repressor 1
6688 SPI1; Spi-1 proto-oncogene
1050 CEBPA; CCAAT enhancer binding protein alpha
1438 CSF2RA; colony stimulating factor 2 receptor subunit alpha
1441 CSF3R; colony stimulating factor 3 receptor
1436 CSF1R; colony stimulating factor 1 receptor
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
4149 MAX; MYC associated factor X
7709 ZBTB17; zinc finger and BTB domain containing 17
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1021 CDK6; cyclin dependent kinase 6
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1163 CKS1B; CDC28 protein kinase regulatory subunit 1B
1164 CKS2; CDC28 protein kinase regulatory subunit 2
6500 SKP1; S-phase kinase associated protein 1
8454 CUL1; cullin 1
9978 RBX1; ring-box 1
6502 SKP2; S-phase kinase associated protein 2
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
4286 MITF; melanocyte inducing transcription factor
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
2122 MECOM; MDS1 and EVI1 complex locus
1487 CTBP1; C-terminal binding protein 1
1488 CTBP2; C-terminal binding protein 2
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
4292 MLH1; mutL homolog 1
4436 MSH2; mutS homolog 2
4437 MSH3; mutS homolog 3
2956 MSH6; mutS homolog 6
675 BRCA2; BRCA2 DNA repair associated
5888 RAD51; RAD51 recombinase
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
841 CASP8; caspase 8
637 BID; BH3 interacting domain death agonist
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
27113 BBC3; BCL2 binding component 3
10018 BCL2L11; BCL2 like 11
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
840 CASP7; caspase 7
9817 KEAP1; kelch like ECH associated protein 1
4780 NFE2L2; nuclear factor, erythroid 2 like 2
3162 HMOX1; heme oxygenase 1
1728 NQO1; NAD(P)H quinone dehydrogenase 1
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
2950 GSTP1; glutathione S-transferase pi 1
7296 TXNRD1; thioredoxin reductase 1
114112 TXNRD3; thioredoxin reductase 3
10587 TXNRD2; thioredoxin reductase 2
7428 VHL; von Hippel-Lindau tumor suppressor
6921 ELOC; elongin C
6923 ELOB; elongin B
8453 CUL2; cullin 2
54583 EGLN1; egl-9 family hypoxia inducible factor 1
112399 EGLN3; egl-9 family hypoxia inducible factor 3
112398 EGLN2; egl-9 family hypoxia inducible factor 2
2271 FH; fumarate hydratase
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
2034 EPAS1; endothelial PAS domain protein 1
405 ARNT; aryl hydrocarbon receptor nuclear translocator
9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
6513 SLC2A1; solute carrier family 2 member 1
182 JAG1; jagged canonical Notch ligand 1
3714 JAG2; jagged canonical Notch ligand 2
10683 DLL3; delta like canonical Notch ligand 3
28514 DLL1; delta like canonical Notch ligand 1
54567 DLL4; delta like canonical Notch ligand 4
4851 NOTCH1; notch receptor 1
4853 NOTCH2; notch receptor 2
4854 NOTCH3; notch receptor 3
4855 NOTCH4; notch receptor 4
3280 HES1; hes family bHLH transcription factor 1
388585 HES5; hes family bHLH transcription factor 5
26508 HEYL; hes related family bHLH transcription factor with YRPW motif like
23462 HEY1; hes related family bHLH transcription factor with YRPW motif 1
23493 HEY2; hes related family bHLH transcription factor with YRPW motif 2
2324 FLT4; fms related receptor tyrosine kinase 4
6469 SHH; sonic hedgehog signaling molecule
5727 PTCH1; patched 1
6608 SMO; smoothened, frizzled class receptor
374654 KIF7; kinesin family member 7
51684 SUFU; SUFU negative regulator of hedgehog signaling
2735 GLI1; GLI family zinc finger 1
2736 GLI2; GLI family zinc finger 2
2737 GLI3; GLI family zinc finger 3
650 BMP2; bone morphogenetic protein 2
652 BMP4; bone morphogenetic protein 4
64399 HHIP; hedgehog interacting protein
8643 PTCH2; patched 2
367 AR; androgen receptor
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
7184 HSP90B1; heat shock protein 90 beta family member 1
354 KLK3; kallikrein related peptidase 3
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; probable transcription factor PML
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
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05202 Transcriptional misregulation in cancer [PATH:hsa05202]
|
05206 MicroRNAs in cancer [PATH:hsa05206]
|
406952 MIR17; microRNA 17
406953 MIR18A; microRNA 18a
406979 MIR19A; microRNA 19a
406981 MIR19B2; microRNA 19b-2
406980 MIR19B1; microRNA 19b-1
406982 MIR20A; microRNA 20a
407048 MIR92A1; microRNA 92a-1
407049 MIR92A2; microRNA 92a-2
5728 PTEN; phosphatase and tensin homolog
407006 MIR221; microRNA 221
407007 MIR222; microRNA 222
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
406991 MIR21; microRNA 21
7078 TIMP3; TIMP metallopeptidase inhibitor 3
406881 MIRLET7A1; microRNA let-7a-1
406882 MIRLET7A2; microRNA let-7a-2
406883 MIRLET7A3; microRNA let-7a-3
406884 MIRLET7B; microRNA let-7b
406886 MIRLET7D; microRNA let-7d
406887 MIRLET7E; microRNA let-7e
406888 MIRLET7F1; microRNA let-7f-1
406889 MIRLET7F2; microRNA let-7f-2
406890 MIRLET7G; microRNA let-7g
406891 MIRLET7I; microRNA let-7i
406885 MIRLET7C; microRNA let-7c
3845 KRAS; KRAS proto-oncogene, GTPase
1021 CDK6; cyclin dependent kinase 6
993 CDC25A; cell division cycle 25A
994 CDC25B; cell division cycle 25B
995 CDC25C; cell division cycle 25C
8091 HMGA2; high mobility group AT-hook 2
406901 MIR107; microRNA 107
406948 MIR15A; microRNA 15a
406949 MIR15B; microRNA 15b
406950 MIR16-1; microRNA 16-1
406951 MIR16-2; microRNA 16-2
595 CCND1; cyclin D1
894 CCND2; cyclin D2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
406913 MIR126; microRNA 126
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
406904 MIR1-1; microRNA 1-1
406905 MIR1-2; microRNA 1-2
9759 HDAC4; histone deacetylase 4
10014 HDAC5; histone deacetylase 5
27086 FOXP1; forkhead box P1
5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
4233 MET; MET proto-oncogene, receptor tyrosine kinase
407021 MIR29A; microRNA 29a
407024 MIR29B1; microRNA 29b-1
407025 MIR29B2; microRNA 29b-2
407026 MIR29C; microRNA 29c
1788 DNMT3A; DNA methyltransferase 3 alpha
1789 DNMT3B; DNA methyltransferase 3 beta
406922 MIR133A1; microRNA 133a-1
406923 MIR133A2; microRNA 133a-2
442890 MIR133B; microRNA 133b
4170 MCL1; MCL1 apoptosis regulator, BCL2 family member
599 BCL2L2; BCL2 like 2
406937 MIR145; microRNA 145
1956 EGFR; epidermal growth factor receptor
7422 VEGFA; vascular endothelial growth factor A
406985 MIR200C; microRNA 200c
6935 ZEB1; zinc finger E-box binding homeobox 1
406933 MIR141; microRNA 141
7042 TGFB2; transforming growth factor beta 2
406959 MIR183; microRNA 183
7430 EZR; ezrin
406910 MIR125A; microRNA 125a
406911 MIR125B1; microRNA 125b-1
406912 MIR125B2; microRNA 125b-2
27250 PDCD4; programmed cell death 4
406935 MIR143; microRNA 143
406967 MIR192; microRNA 192
406969 MIR194-1; microRNA 194-1
406970 MIR194-2; microRNA 194-2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
406997 MIR215; microRNA 215
407020 MIR28; microRNA 28
407034 MIR30E; microRNA 30e
407033 MIR30D; microRNA 30d
407029 MIR30A; microRNA 30a
407030 MIR30B; microRNA 30b
407031 MIR30C1; microRNA 30c-1
407032 MIR30C2; microRNA 30c-2
7168 TPM1; tropomyosin 1
10253 SPRY2; sprouty RTK signaling antagonist 2
596 BCL2; BCL2 apoptosis regulator
5268 SERPINB5; serpin family B member 5
406947 MIR155; microRNA 155
406986 MIR203A; microRNA 203a
100616173 MIR203B; microRNA 203b
406988 MIR205; microRNA 205
407018 MIR27A; microRNA 27a
407019 MIR27B; microRNA 27b
6768 ST14; ST14 transmembrane serine protease matriptase
1545 CYP1B1; cytochrome P450 family 1 subfamily B member 1
407035 MIR31; microRNA 31
407055 MIR99A; microRNA 99a
406892 MIR100; microRNA 100
2475 MTOR; mechanistic target of rapamycin kinase
57521 RPTOR; regulatory associated protein of MTOR complex 1
1591 CYP24A1; cytochrome P450 family 24 subfamily A member 1
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
8626 TP63; tumor protein p63
9839 ZEB2; zinc finger E-box binding homeobox 2
6624 FSCN1; fascin actin-bundling protein 1
494324 MIR375; microRNA 375
693187 MIR602; microRNA 602
11186 RASSF1; Ras association domain family member 1
406903 MIR10B; microRNA 10b
3236 HOXD10; homeobox D10
54541 DDIT4; DNA damage inducible transcript 4
90427 BMF; Bcl2 modifying factor
407009 MIR224; microRNA 224
10298 PAK4; p21 (RAC1) activated kinase 4
4318 MMP9; matrix metallopeptidase 9
574031 MIR363; microRNA 363
574452 MIR494; microRNA 494
693200 MIR615; microRNA 615
693210 MIR625; microRNA 625
407014 MIR25; microRNA 25
407040 MIR34A; microRNA 34a
407053 MIR96; microRNA 96
406902 MIR10A; microRNA 10a
407010 MIR23A; microRNA 23a
407011 MIR23B; microRNA 23b
100500809 MIR23C; microRNA 23c
406906 MIR122; microRNA 122
6541 SLC7A1; solute carrier family 7 member 1
900 CCNG1; cyclin G1
3162 HMOX1; heme oxygenase 1
406942 MIR150; microRNA 150
407008 MIR223; microRNA 223
3925 STMN1; stathmin 1
442909 MIR342; microRNA 342
494335 MIR423; microRNA 423
6774 STAT3; signal transducer and activator of transcription 3
4609 MYC; MYC proto-oncogene, bHLH transcription factor
836 CASP3; caspase 3
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
406978 MIR199B; microRNA 199b
442898 MIR324; microRNA 324
619552 MIR483; microRNA 483
407015 MIR26A1; microRNA 26a-1
407016 MIR26A2; microRNA 26a-2
407017 MIR26B; microRNA 26b
406943 MIR152; microRNA 152
1786 DNMT1; DNA methyltransferase 1
442891 MIR135B; microRNA 135b
406926 MIR135A2; microRNA 135a-2
406925 MIR135A1; microRNA 135a-1
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
3667 IRS1; insulin receptor substrate 1
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5598 MAPK7; mitogen-activated protein kinase 7
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
406983 MIR200A; microRNA 200a
406984 MIR200B; microRNA 200b
3190 HNRNPK; heterogeneous nuclear ribonucleoprotein K
8434 RECK; reversion inducing cysteine rich protein with kazal motifs
406907 MIR124-1; microRNA 124-1
406909 MIR124-3; microRNA 124-3
406908 MIR124-2; microRNA 124-2
406928 MIR137; microRNA 137
406915 MIR128-1; microRNA 128-1
406916 MIR128-2; microRNA 128-2
1871 E2F3; E2F transcription factor 3
407043 MIR7-1; microRNA 7-1
407044 MIR7-2; microRNA 7-2
407045 MIR7-3; microRNA 7-3
8660 IRS2; insulin receptor substrate 2
442900 MIR326; microRNA 326
4851 NOTCH1; notch receptor 1
4853 NOTCH2; notch receptor 2
4854 NOTCH3; notch receptor 3
4855 NOTCH4; notch receptor 4
648 BMI1; BMI1 proto-oncogene, polycomb ring finger
100532731 COMMD3-BMI1; COMMD3-BMI1 readthrough
406938 MIR146A; microRNA 146a
4325 MMP16; matrix metallopeptidase 16
406954 MIR181A2; microRNA 181a-2
406995 MIR181A1; microRNA 181a-1
406955 MIR181B1; microRNA 181b-1
406956 MIR181B2; microRNA 181b-2
406957 MIR181C; microRNA 181c
574457 MIR181D; microRNA 181d
472 ATM; ATM serine/threonine kinase
8651 SOCS1; suppressor of cytokine signaling 1
442918 MIR373; microRNA 373
574467 MIR520A; microRNA 520a
574484 MIR520G; microRNA 520g
574493 MIR520H; microRNA 520h
574473 MIR520B; microRNA 520b
574461 MIR520E; microRNA 520e
960 CD44; CD44 molecule (Indian blood group)
406895 MIR103A1; microRNA 103a-1
100302282 MIR103B2; microRNA 103b-2
406896 MIR103A2; microRNA 103a-2
100302238 MIR103B1; microRNA 103b-1
23405 DICER1; dicer 1, ribonuclease III
7976 FZD3; frizzled class receptor 3
3678 ITGA5; integrin subunit alpha 5
5962 RDX; radixin
387 RHOA; ras homolog family member A
574455 MIR193B; microRNA 193b
5328 PLAU; plasminogen activator, urokinase
578 BAK1; BCL2 antagonist/killer 1
23414 ZFPM2; zinc finger protein, FOG family member 2
3690 ITGB3; integrin subunit beta 3
7329 UBE2I; ubiquitin conjugating enzyme E2 I
442904 MIR335; microRNA 335
6659 SOX4; SRY-box transcription factor 4
3371 TNC; tenascin C
63923 TNN; tenascin N
7143 TNR; tenascin R
7148 TNXB; tenascin XB
406989 MIR206; microRNA 206
574411 MIR451A; microRNA 451a
5243 ABCB1; ATP binding cassette subfamily B member 1
442910 MIR345; microRNA 345
4363 ABCC1; ATP binding cassette subfamily C member 1
406996 MIR214; microRNA 214
672 BRCA1; BRCA1 DNA repair associated
406900 MIR106B; microRNA 106b
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
406992 MIR210; microRNA 210
1942 EFNA1; ephrin A1
1943 EFNA2; ephrin A2
1944 EFNA3; ephrin A3
1945 EFNA4; ephrin A4
1946 EFNA5; ephrin A5
7057 THBS1; thrombospondin 1
10642 IGF2BP1; insulin like growth factor 2 mRNA binding protein 1
131405 TRIM71; tripartite motif containing 71
407041 MIR34B; microRNA 34b
407042 MIR34C; microRNA 34c
407046 MIR9-1; microRNA 9-1
407047 MIR9-2; microRNA 9-2
407051 MIR9-3; microRNA 9-3
4790 NFKB1; nuclear factor kappa B subunit 1
406976 MIR199A1; microRNA 199a-1
406977 MIR199A2; microRNA 199a-2
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
5743 PTGS2; prostaglandin-endoperoxide synthase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
2885 GRB2; growth factor receptor bound protein 2
2261 FGFR3; fibroblast growth factor receptor 3
9252 RPS6KA5; ribosomal protein S6 kinase A5
7157 TP53; tumor protein p53
4193 MDM2; MDM2 proto-oncogene
4194 MDM4; MDM4 regulator of p53
5156 PDGFRA; platelet derived growth factor receptor alpha
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
406893 MIR101-1; microRNA 101-1
406894 MIR101-2; microRNA 101-2
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
406971 MIR195; microRNA 195
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
6464 SHC1; SHC adaptor protein 1
5154 PDGFA; platelet derived growth factor subunit A
406917 MIR129-1; microRNA 129-1
406918 MIR129-2; microRNA 129-2
399694 SHC4; SHC adaptor protein 4
5155 PDGFB; platelet derived growth factor subunit B
5159 PDGFRB; platelet derived growth factor receptor beta
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
407036 MIR32; microRNA 32
10018 BCL2L11; BCL2 like 11
4082 MARCKS; myristoylated alanine rich protein kinase C substrate
659 BMPR2; bone morphogenetic protein receptor type 2
554213 MIR449A; microRNA 449a
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
2146 EZH2; enhancer of zeste 2 polycomb repressive complex 2 subunit
27165 GLS2; glutaminase 2
2744 GLS; glutaminase
23411 SIRT1; sirtuin 1
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
442902 MIR330; microRNA 330
442903 MIR331; microRNA 331
113130 CDCA5; cell division cycle associated 5
9493 KIF23; kinesin family member 23
574476 MIR520C; microRNA 520c
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
5581 PRKCE; protein kinase C epsilon
85414 SLC45A3; solute carrier family 45 member 3
7431 VIM; vimentin
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K17002 MIR17; microRNA 17
K17003 MIR18A; microRNA 18a
K17005 MIR19A; microRNA 19a
K23559 MIR19B; microRNA 19b
K23559 MIR19B; microRNA 19b
K17006 MIR20A; microRNA 20a
K17008 MIR92A; microRNA 92a
K17008 MIR92A; microRNA 92a
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K17010 MIR221; microRNA 221
K17011 MIR222; microRNA 222
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16863 MIR21; microRNA 21
K16866 TIMP3; metalloproteinase inhibitor 3
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K17397 MIRLET7C; microRNA let-7c
K07827 KRAS; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K17396 MIR107; microRNA 107
K16986 MIR15A; microRNA 15a
K16987 MIR15B; microRNA 15b
K16988 MIR16; microRNA 16
K16988 MIR16; microRNA 16
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K16978 MIR126; microRNA 126
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K16972 MIR1; microRNA 1
K16972 MIR1; microRNA 1
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K16995 MIR29A; microRNA 29a
K16996 MIR29B; microRNA 29b
K16996 MIR29B; microRNA 29b
K16997 MIR29C; microRNA 29c
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K16970 MIR133A; microRNA 133a
K16970 MIR133A; microRNA 133a
K16971 MIR133B; microRNA 133b
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K16974 MIR145; microRNA 145
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K17017 MIR200C; microRNA 200c
K09299 ZEB1; zinc finger homeobox protein 1
K17018 MIR141; microRNA 141
K13376 TGFB2; transforming growth factor beta-2
K17116 MIR183; microRNA 183
K08007 VIL2; villin 2 (ezrin)
K16993 MIR125A; microRNA 125a
K16994 MIR125B; microRNA 125b
K16994 MIR125B; microRNA 125b
K16865 PDCD4; programmed cell death protein 4
K17023 MIR143; microRNA 143
K17131 MIR192; microRNA 192
K17371 MIR194; microRNA 194
K17371 MIR194; microRNA 194
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K17167 MIR215; microRNA 215
K17366 MIR28; microRNA 28
K17110 MIR30A_D_E; microRNA 30a/d/e
K17110 MIR30A_D_E; microRNA 30a/d/e
K17110 MIR30A_D_E; microRNA 30a/d/e
K17111 MIR30B; microRNA 30b
K17040 MIR30C; microRNA 30c
K17040 MIR30C; microRNA 30c
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K17009 MIR155; microRNA 155
K16975 MIR203; microRNA 203
K16975 MIR203; microRNA 203
K17150 MIR205; microRNA 205
K17112 MIR27A; microRNA 27a
K17113 MIR27B; microRNA 27b
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17183 MIR31; microRNA 31
K17367 MIR99A; microRNA 99a
K17041 MIR100; microRNA 100
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K16976 MIR375; microRNA 375
K17379 MIR602; microRNA 602
K09850 RASSF1; Ras association domain-containing protein 1
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K17042 MIR224; microRNA 224
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K17036 MIR363; microRNA 363
K17378 MIR494; microRNA 494
K17380 MIR615; microRNA 615
K17381 MIR625; microRNA 625
K17038 MIR25; microRNA 25
K16982 MIR34A; microRNA 34a
K17114 MIR96; microRNA 96
K16864 MIR10A; microRNA 10a
K17165 MIR23A; microRNA 23a
K17394 MIR23B; microRNA 23b
K17395 MIR23C; microRNA 23c
K17020 MIR122; microRNA 122
K13863 SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K17024 MIR150; microRNA 150
K17001 MIR223; microRNA 223
K04381 STMN1; stathmin
K17132 MIR342; microRNA 342
K17376 MIR423; microRNA 423
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K17119 MIR199B; microRNA 199b
K17152 MIR324; microRNA 324
K17137 MIR483; microRNA 483
K16984 MIR26A; microRNA 26a
K16984 MIR26A; microRNA 26a
K16985 MIR26B; microRNA 26b
K17370 MIR152; microRNA 152
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K17144 MIR135; microRNA 135
K17144 MIR135; microRNA 135
K17144 MIR135; microRNA 135
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K17015 MIR200A; microRNA 200a
K17016 MIR200B; microRNA 200b
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK; reversion-inducing-cysteine-rich protein with kazal motifs
K17126 MIR124; microRNA 124
K17126 MIR124; microRNA 124
K17126 MIR124; microRNA 124
K17369 MIR137; microRNA 137
K17130 MIR128; microRNA 128
K17130 MIR128; microRNA 128
K06620 E2F3; transcription factor E2F3
K17365 MIR7; microRNA 7
K17365 MIR7; microRNA 7
K17365 MIR7; microRNA 7
K07187 IRS2; insulin receptor substrate 2
K17372 MIR326; microRNA 326
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K11459 PCGF4; polycomb group RING finger protein 4
K11459 PCGF4; polycomb group RING finger protein 4
K17012 MIR146A; microRNA 146a
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K17025 MIR181A; microRNA 181a
K17025 MIR181A; microRNA 181a
K17026 MIR181B; microRNA 181b
K17026 MIR181B; microRNA 181b
K17027 MIR181C; microRNA 181c
K17028 MIR181D; microRNA 181d
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K17000 MIR373; microRNA 373
K17175 MIR520; microRNA 520
K17175 MIR520; microRNA 520
K17175 MIR520; microRNA 520
K17175 MIR520; microRNA 520
K17175 MIR520; microRNA 520
K06256 CD44; CD44 antigen
K16989 MIR103; microRNA 103
K16989 MIR103; microRNA 103
K16989 MIR103; microRNA 103
K16989 MIR103; microRNA 103
K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K17148 MIR193B; microRNA 193b
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK; Bcl-2 homologous antagonist/killer
K17442 ZFPM2; zinc finger protein ZFPM2
K06493 ITGB3; integrin beta 3
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K17033 MIR335; microRNA 335
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K16973 MIR206; microRNA 206
K17172 MIR451; microRNA 451
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K17375 MIR345; microRNA 345
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K17151 MIR214; microRNA 214
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K17035 MIR106B; microRNA 106b
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K17178 MIR210; microRNA 210
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K16983 MIR34B; microRNA 34b
K23572 MIR34C; microRNA 34c
K16977 MIR9; microRNA 9
K16977 MIR9; microRNA 9
K16977 MIR9; microRNA 9
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K17118 MIR199A; microRNA 199a
K17118 MIR199A; microRNA 199a
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K17129 MIR101; microRNA 101
K17129 MIR101; microRNA 101
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K17029 MIR195; microRNA 195
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17368 MIR129; microRNA 129
K17368 MIR129; microRNA 129
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K17039 MIR32; microRNA 32
K16341 BCL2L11; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K17377 MIR449A; microRNA 449a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17373 MIR330; microRNA 330
K17374 MIR331; microRNA 331
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K17389 MIR520C; microRNA 520c
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
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05205 Proteoglycans in cancer [PATH:hsa05205]
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960 CD44; CD44 molecule (Indian blood group)
6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
2017 CTTN; cortactin
3059 HCLS1; hematopoietic cell-specific Lyn substrate 1
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2885 GRB2; growth factor receptor bound protein 2
10451 VAV3; vav guanine nucleotide exchange factor 3
7409 VAV1; vav guanine nucleotide exchange factor 1
7410 VAV2; vav guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
6237 RRAS; RAS related
22800 RRAS2; RAS related 2
22808 MRAS; muscle RAS oncogene homolog
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5879 RAC1; Rac family small GTPase 1
8826 IQGAP1; IQ motif containing GTPase activating protein 1
998 CDC42; cell division cycle 42
2002 ELK1; ETS transcription factor ELK1
2099 ESR1; estrogen receptor 1
595 CCND1; cyclin D1
71 ACTG1; actin gamma 1
60 ACTB; actin beta
2316 FLNA; filamin A
2318 FLNC; filamin C
2317 FLNB; filamin B
5058 PAK1; p21 (RAC1) activated kinase 1
7074 TIAM1; TIAM Rac1 associated GEF 1
9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
286 ANK1; ankyrin 1
287 ANK2; ankyrin 2
288 ANK3; ankyrin 3
2549 GAB1; GRB2 associated binding protein 1
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
6548 SLC9A1; solute carrier family 9 member A1
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
4660 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
54776 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
51196 PLCE1; phospholipase C epsilon 1
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
79923 NANOG; Nanog homeobox
388112 NANOGP8; Nanog homeobox retrogene P8
1655 DDX5; DEAD-box helicase 5
29102 DROSHA; drosha ribonuclease III
6774 STAT3; signal transducer and activator of transcription 3
406991 MIR21; microRNA 21
7291 TWIST1; twist family bHLH transcription factor 1
117581 TWIST2; twist family bHLH transcription factor 2
406902 MIR10A; microRNA 10a
406903 MIR10B; microRNA 10b
3236 HOXD10; homeobox D10
1634 DCN; decorin
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
2475 MTOR; mechanistic target of rapamycin kinase
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1975 EIF4B; eukaryotic translation initiation factor 4B
6194 RPS6; ribosomal protein S6
1956 EGFR; epidermal growth factor receptor
857 CAV1; caveolin 1
858 CAV2; caveolin 2
859 CAV3; caveolin 3
967 CD63; CD63 molecule
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
836 CASP3; caspase 3
7040 TGFB1; transforming growth factor beta 1
7097 TLR2; toll like receptor 2
7099 TLR4; toll like receptor 4
27250 PDCD4; programmed cell death 4
7124 TNF; tumor necrosis factor
3593 IL12B; interleukin 12B
2065 ERBB3; erb-b2 receptor tyrosine kinase 3
2066 ERBB4; erb-b2 receptor tyrosine kinase 4
4609 MYC; MYC proto-oncogene, bHLH transcription factor
1499 CTNNB1; catenin beta 1
3091 HIF1A; hypoxia inducible factor 1 subunit alpha
7023 TFAP4; transcription factor AP-4
7422 VEGFA; vascular endothelial growth factor A
3791 KDR; kinase insert domain receptor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
867 CBL; Cbl proto-oncogene
7078 TIMP3; TIMP metallopeptidase inhibitor 3
7057 THBS1; thrombospondin 1
4313 MMP2; matrix metallopeptidase 2
4318 MMP9; matrix metallopeptidase 9
4060 LUM; lumican
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
7042 TGFB2; transforming growth factor beta 2
4087 SMAD2; SMAD family member 2
10855 HPSE; heparanase
60495 HPSE2; heparanase 2 (inactive)
6382 SDC1; syndecan 1
5328 PLAU; plasminogen activator, urokinase
5329 PLAUR; plasminogen activator, urokinase receptor
1277 COL1A1; collagen type I alpha 1 chain
1278 COL1A2; collagen type I alpha 2 chain
3673 ITGA2; integrin subunit alpha 2
3688 ITGB1; integrin subunit beta 1
7448 VTN; vitronectin
3685 ITGAV; integrin subunit alpha V
3690 ITGB3; integrin subunit beta 3
2335 FN1; fibronectin 1
3693 ITGB5; integrin subunit beta 5
3082 HGF; hepatocyte growth factor
7471 WNT1; Wnt family member 1
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
3678 ITGA5; integrin subunit alpha 5
6383 SDC2; syndecan 2
7430 EZR; ezrin
5962 RDX; radixin
4478 MSN; moesin
6385 SDC4; syndecan 4
2247 FGF2; fibroblast growth factor 2
2260 FGFR1; fibroblast growth factor receptor 1
10818 FRS2; fibroblast growth factor receptor substrate 2
5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
84309 NUDT16L1; nudix hydrolase 16 like 1
5829 PXN; paxillin
5747 PTK2; protein tyrosine kinase 2
1839 HBEGF; heparin binding EGF like growth factor
2817 GPC1; glypican 1
3481 IGF2; insulin like growth factor 2
2719 GPC3; glypican 3
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
6469 SHH; sonic hedgehog signaling molecule
3549 IHH; Indian hedgehog signaling molecule
5727 PTCH1; patched 1
6608 SMO; smoothened, frizzled class receptor
3339 HSPG2; heparan sulfate proteoglycan 2
1514 CTSL; cathepsin L
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
3316 HSPB2; heat shock protein family B (small) member 2
5777 PTPN6; protein tyrosine phosphatase non-receptor type 6
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K06256 CD44; CD44 antigen
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06106 CTTN; cortactin
K06106 CTTN; cortactin
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K04393 CDC42; cell division control protein 42
K04375 ELK1; ETS domain-containing protein Elk-1
K08550 ESR1; estrogen receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04437 FLNA; filamin
K04437 FLNA; filamin
K04437 FLNA; filamin
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10380 ANK; ankyrin
K10380 ANK; ankyrin
K10380 ANK; ankyrin
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K10164 NANOG; homeobox protein Nanog
K10164 NANOG; homeobox protein Nanog
K12823 DDX5; ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
K03685 rnc; ribonuclease III [EC:3.1.26.3]
K04692 STAT3; signal transducer and activator of transcription 3
K16863 MIR21; microRNA 21
K09069 TWIST; twist
K09069 TWIST; twist
K16864 MIR10A; microRNA 10a
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K04660 DCN; decorin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e; small subunit ribosomal protein S6e
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K06497 CD63; CD63 antigen
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13375 TGFB1; transforming growth factor beta-1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K16865 PDCD4; programmed cell death protein 4
K03156 TNF; tumor necrosis factor superfamily, member 2
K05425 IL12B; interleukin 12B
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04377 MYC; Myc proto-oncogene protein
K02105 CTNNB1; catenin beta 1
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09108 TFAP4; transcription factor AP-4
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K16866 TIMP3; metalloproteinase inhibitor 3
K16857 THBS1; thrombospondin 1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08122 LUM; lumican
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K13376 TGFB2; transforming growth factor beta-2
K04500 SMAD2; mothers against decapentaplegic homolog 2
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K06257 SDC1; syndecan 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03985 PLAUR; plasminogen activator, urokinase receptor
K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K06481 ITGA2; integrin alpha 2
K05719 ITGB1; integrin beta 1
K06251 VTN; vitronectin
K06487 ITGAV; integrin alpha V
K06493 ITGB3; integrin beta 3
K05717 FN1; fibronectin 1
K06588 ITGB5; integrin beta 5
K05460 HGF; hepatocyte growth factor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K06484 ITGA5; integrin alpha 5
K16336 SDC2; syndecan 2
K08007 VIL2; villin 2 (ezrin)
K05762 RDX; radixin
K05763 MSN; moesin
K16338 SDC4; syndecan 4
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K12461 FRS2; fibroblast growth factor receptor substrate 2
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K16867 NUDT16L1; NUDT16-like protein 1
K05760 PXN; paxillin
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08107 GPC1; glypican 1
K13769 IGF2; insulin-like growth factor 2
K08109 GPC3; glypican 3
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K11988 SHH; sonic hedgehog
K11989 IHH; indian hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K09543 HSPB2; heat shock protein beta-2
K05697 PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
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05204 Chemical carcinogenesis [PATH:hsa05204]
|
05203 Viral carcinogenesis [PATH:hsa05203]
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6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
1642 DDB1; damage specific DNA binding protein 1
7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
3716 JAK1; Janus kinase 1
6774 STAT3; signal transducer and activator of transcription 3
6776 STAT5A; signal transducer and activator of transcription 5A
6777 STAT5B; signal transducer and activator of transcription 5B
836 CASP3; caspase 3
3249 HPN; hepsin
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5970 RELA; RELA proto-oncogene, NF-kB subunit
5966 REL; REL proto-oncogene, NF-kB subunit
4791 NFKB2; nuclear factor kappa B subunit 2
4790 NFKB1; nuclear factor kappa B subunit 1
7157 TP53; tumor protein p53
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
1017 CDK2; cyclin dependent kinase 2
1959 EGR2; early growth response 2
1960 EGR3; early growth response 3
7419 VDAC3; voltage dependent anion channel 3
4055 LTBR; lymphotoxin beta receptor
6672 SP100; SP100 nuclear antigen
3190 HNRNPK; heterogeneous nuclear ribonucleoprotein K
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1654 DDX3X; DEAD-box helicase 3 X-linked
5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
8341 H2BC15; H2B clustered histone 15
8345 H2BC9; H2B clustered histone 9
8342 H2BC14; H2B clustered histone 14
158983 H2BW1; H2B.W histone 1
255626 H2BC1; H2B clustered histone 1
440689 H2BC18; H2B clustered histone 18
8348 H2BC17; H2B clustered histone 17
3018 H2BC3; H2B clustered histone 3
8339 H2BC8; H2B clustered histone 8
8340 H2BC13; H2B clustered histone 13
8347 H2BC4; H2B clustered histone 4
3017 H2BC5; H2B clustered histone 5
8344 H2BC6; H2B clustered histone 6
8346 H2BC10; H2B clustered histone 10
8349 H2BC21; H2B clustered histone 21
8970 H2BC11; H2B clustered histone 11
85236 H2BC12; H2B clustered histone 12
128312 H2BU1; H2B.U histone 1
8343 H2BC7; H2B clustered histone 7
286436 H2BW2; H2B.W histone 2
102724334 histone H2B type F-S-like
114483833 H2BE1; H2B.E variant histone 1
54145 H2BS1; H2B.S histone 1
121504 H4-16; H4 histone 16
554313 H4C15; H4 clustered histone 15
8294 H4C9; H4 clustered histone 9
8360 H4C4; H4 clustered histone 4
8361 H4C6; H4 clustered histone 6
8362 H4C12; H4 clustered histone 12
8363 H4C11; H4 clustered histone 11
8364 H4C3; H4 clustered histone 3
8365 H4C8; H4 clustered histone 8
8366 H4C2; H4 clustered histone 2
8367 H4C5; H4 clustered histone 5
8368 H4C13; H4 clustered histone 13
8370 H4C14; H4 clustered histone 14
8359 H4C1; H4 clustered histone 1
8369 H4C7; H4 clustered histone 7
581 BAX; BCL2 associated X, apoptosis regulator
2885 GRB2; growth factor receptor bound protein 2
8717 TRADD; TNFRSF1A associated via death domain
983 CDK1; cyclin dependent kinase 1
387332 TBPL2; TATA-box binding protein like 2
9519 TBPL1; TATA-box binding protein like 1
6908 TBP; TATA-box binding protein
7874 USP7; ubiquitin specific peptidase 7
4193 MDM2; MDM2 proto-oncogene
11317 RBPJL; recombination signal binding protein for immunoglobulin kappa J region like
3516 RBPJ; recombination signal binding protein for immunoglobulin kappa J region
22938 SNW1; SNW domain containing 1
2965 GTF2H1; general transcription factor IIH subunit 1
2966 GTF2H2; general transcription factor IIH subunit 2
730394 GTF2H2C_2; GTF2H2 family member C, copy 2
728340 GTF2H2C; GTF2H2 family member C
2967 GTF2H3; general transcription factor IIH subunit 3
2968 GTF2H4; general transcription factor IIH subunit 4
2960 GTF2E1; general transcription factor IIE subunit 1
2961 GTF2E2; general transcription factor IIE subunit 2
27044 SND1; staphylococcal nuclease and tudor domain containing 1
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
2959 GTF2B; general transcription factor IIB
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1021 CDK6; cyclin dependent kinase 6
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
6502 SKP2; S-phase kinase associated protein 2
28973 MRPS18B; mitochondrial ribosomal protein S18B
7185 TRAF1; TNF receptor associated factor 1
7186 TRAF2; TNF receptor associated factor 2
7187 TRAF3; TNF receptor associated factor 3
7188 TRAF5; TNF receptor associated factor 5
3718 JAK3; Janus kinase 3
4067 LYN; LYN proto-oncogene, Src family tyrosine kinase
6850 SYK; spleen associated tyrosine kinase
9114 ATP6V0D1; ATPase H+ transporting V0 subunit d1
245972 ATP6V0D2; ATPase H+ transporting V0 subunit d2
7337 UBE3A; ubiquitin protein ligase E3A
1739 DLG1; discs large MAGUK scaffold protein 1
23513 SCRIB; scribble planar cell polarity protein
5829 PXN; paxillin
578 BAK1; BCL2 antagonist/killer 1
3661 IRF3; interferon regulatory factor 3
5700 PSMC1; proteasome 26S subunit, ATPase 1
5925 RB1; RB transcriptional corepressor 1
5933 RBL1; RB transcriptional corepressor like 1
5934 RBL2; RB transcriptional corepressor like 2
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
23352 UBR4; ubiquitin protein ligase E3 component n-recognin 4
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
1108 CHD4; chromodomain helicase DNA binding protein 4
3065 HDAC1; histone deacetylase 1
3066 HDAC2; histone deacetylase 2
8841 HDAC3; histone deacetylase 3
9759 HDAC4; histone deacetylase 4
10014 HDAC5; histone deacetylase 5
10013 HDAC6; histone deacetylase 6
51564 HDAC7; histone deacetylase 7
55869 HDAC8; histone deacetylase 8
9734 HDAC9; histone deacetylase 9
83933 HDAC10; histone deacetylase 10
79885 HDAC11; histone deacetylase 11
5315 PKM; pyruvate kinase M1/2
10379 IRF9; interferon regulatory factor 9
9093 DNAJA3; DnaJ heat shock protein family (Hsp40) member A3
8850 KAT2B; lysine acetyltransferase 2B
2648 KAT2A; lysine acetyltransferase 2A
11036 GTF2A1L; general transcription factor IIA subunit 1 like
2957 GTF2A1; general transcription factor IIA subunit 1
2958 GTF2A2; general transcription factor IIA subunit 2
6722 SRF; serum response factor
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
5922 RASA2; RAS p21 protein activator 2
998 CDC42; cell division cycle 42
5879 RAC1; Rac family small GTPase 1
387 RHOA; ras homolog family member A
2934 GSN; gelsolin
85477 SCIN; scinderin
87 ACTN1; actinin alpha 1
81 ACTN4; actinin alpha 4
1019 CDK4; cyclin dependent kinase 4
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
1111 CHEK1; checkpoint kinase 1
991 CDC20; cell division cycle 20
8379 MAD1L1; mitotic arrest deficient 1 like 1
55697 VAC14; VAC14 component of PIKFYVE complex
5902 RANBP1; RAN binding protein 1
5423 POLB; DNA polymerase beta
3665 IRF7; interferon regulatory factor 7
3572 IL6ST; interleukin 6 signal transducer
1234 CCR5; C-C motif chemokine receptor 5
1237 CCR8; C-C motif chemokine receptor 8
1232 CCR3; C-C motif chemokine receptor 3
1233 CCR4; C-C motif chemokine receptor 4
9261 MAPKAPK2; MAPK activated protein kinase 2
841 CASP8; caspase 8
572 BAD; BCL2 associated agonist of cell death
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
718 C3; complement C3
3105 HLA-A; major histocompatibility complex, class I, A
3106 HLA-B; major histocompatibility complex, class I, B
3107 HLA-C; major histocompatibility complex, class I, C
3134 HLA-F; major histocompatibility complex, class I, F
3135 HLA-G; major histocompatibility complex, class I, G
3133 HLA-E; major histocompatibility complex, class I, E
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K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K10610 DDB1; DNA damage-binding protein 1
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08665 HPN; hepsin [EC:3.4.21.106]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04735 RELA; transcription factor p65
K09254 REL; c-Rel proto-oncogene protein
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04451 TP53; tumor protein p53
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K15041 VDAC3; voltage-dependent anion channel protein 3
K03159 TNFRSF3; lymphotoxin beta receptor TNFR superfamily member 3
K15413 SP100; nuclear body protein Sp100
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K02159 BAX; apoptosis regulator BAX
K04364 GRB2; growth factor receptor-bound protein 2
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06063 SNW1; SNW domain-containing protein 1
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
K03137 TFIIE2; transcription initiation factor TFIIE subunit beta
K15979 SND1; staphylococcal nuclease domain-containing protein 1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K03124 TFIIB; transcription initiation factor TFIIB
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K16174 MRPS18B; small subunit ribosomal protein S18b, mitochondrial
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09849 TRAF5; TNF receptor-associated factor 5
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K02146 ATPeV0D; V-type H+-transporting ATPase subunit d
K02146 ATPeV0D; V-type H+-transporting ATPase subunit d
K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
K12076 DLG1; disks large protein 1
K16175 SCRIB; protein scribble
K05760 PXN; paxillin
K14021 BAK; Bcl-2 homologous antagonist/killer
K05411 IRF3; interferon regulatory factor 3
K03062 PSMC1; 26S proteasome regulatory subunit T2
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
K04448 JUN; transcription factor AP-1
K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K04693 IRF9; interferon regulatory factor 9
K09504 DNAJA3; DnaJ homolog subfamily A member 3
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K03122 TFIIA1; transcription initiation factor TFIIA large subunit
K03122 TFIIA1; transcription initiation factor TFIIA large subunit
K03123 TFIIA2; transcription initiation factor TFIIA small subunit
K04378 SRF; serum response factor
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K08053 RASA2; Ras GTPase-activating protein 2
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04513 RHOA; Ras homolog gene family, member A
K05768 GSN; gelsolin
K05768 GSN; gelsolin
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K15305 VAC14; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K09447 IRF7; interferon regulatory factor 7
K05060 IL6ST; interleukin 6 signal transducer
K04180 CCR5; C-C chemokine receptor type 5
K04183 CCR8; C-C chemokine receptor type 8
K04178 CCR3; C-C chemokine receptor type 3
K04179 CCR4; C-C chemokine receptor type 4
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02158 BAD; Bcl-2-antagonist of cell death
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K03990 C3; complement component 3
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
|
05230 Central carbon metabolism in cancer [PATH:hsa05230]
|
05231 Choline metabolism in cancer [PATH:hsa05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:hsa05235]
|
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:hsa05210]
|
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
1499 CTNNB1; catenin beta 1
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
332 BIRC5; baculoviral IAP repeat containing 5
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
3845 KRAS; KRAS proto-oncogene, GTPase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
842 CASP9; caspase 9
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
387 RHOA; ras homolog family member A
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
1630 DCC; DCC netrin 1 receptor
836 CASP3; caspase 3
26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
4292 MLH1; mutL homolog 1
4436 MSH2; mutS homolog 2
4437 MSH3; mutS homolog 3
2956 MSH6; mutS homolog 6
581 BAX; BCL2 associated X, apoptosis regulator
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
10018 BCL2L11; BCL2 like 11
27113 BBC3; BCL2 binding component 3
596 BCL2; BCL2 apoptosis regulator
54205 CYCS; cytochrome c, somatic
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
2069 EREG; epiregulin
374 AREG; amphiregulin
1956 EGFR; epidermal growth factor receptor
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
|
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
|
05212 Pancreatic cancer [PATH:hsa05212]
|
3845 KRAS; KRAS proto-oncogene, GTPase
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
9459 ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor 6
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
842 CASP9; caspase 9
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5900 RALGDS; ral guanine nucleotide dissociation stimulator
5898 RALA; RAS like proto-oncogene A
5899 RALB; RAS like proto-oncogene B
10928 RALBP1; ralA binding protein 1
998 CDC42; cell division cycle 42
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
7039 TGFA; transforming growth factor alpha
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
3716 JAK1; Janus kinase 1
6774 STAT3; signal transducer and activator of transcription 3
6772 STAT1; signal transducer and activator of transcription 1
7422 VEGFA; vascular endothelial growth factor A
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
675 BRCA2; BRCA2 DNA repair associated
5888 RAD51; RAD51 recombinase
|
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05729 ARHGEF6; Rho guanine nucleotide exchange factor 6
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K05448 VEGFA; vascular endothelial growth factor A
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
|
05225 Hepatocellular carcinoma [PATH:hsa05225]
|
7039 TGFA; transforming growth factor alpha
1956 EGFR; epidermal growth factor receptor
3481 IGF2; insulin like growth factor 2
3480 IGF1R; insulin like growth factor 1 receptor
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
2002 ELK1; ETS transcription factor ELK1
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
572 BAD; BCL2 associated agonist of cell death
598 BCL2L1; BCL2 like 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
595 CCND1; cyclin D1
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
9817 KEAP1; kelch like ECH associated protein 1
4780 NFE2L2; nuclear factor, erythroid 2 like 2
3162 HMOX1; heme oxygenase 1
1728 NQO1; NAD(P)H quinone dehydrogenase 1
221357 GSTA5; glutathione S-transferase alpha 5
2939 GSTA2; glutathione S-transferase alpha 2
2941 GSTA4; glutathione S-transferase alpha 4
119391 GSTO2; glutathione S-transferase omega 2
2948 GSTM4; glutathione S-transferase mu 4
2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
2952 GSTT1; glutathione S-transferase theta 1
2947 GSTM3; glutathione S-transferase mu 3
4257 MGST1; microsomal glutathione S-transferase 1
4259 MGST3; microsomal glutathione S-transferase 3
2944 GSTM1; glutathione S-transferase mu 1
2949 GSTM5; glutathione S-transferase mu 5
4258 MGST2; microsomal glutathione S-transferase 2
2938 GSTA1; glutathione S-transferase alpha 1
2946 GSTM2; glutathione S-transferase mu 2
2940 GSTA3; glutathione S-transferase alpha 3
9446 GSTO1; glutathione S-transferase omega 1
653689 GSTT2B; glutathione S-transferase theta 2B
2950 GSTP1; glutathione S-transferase pi 1
7296 TXNRD1; thioredoxin reductase 1
114112 TXNRD3; thioredoxin reductase 3
10587 TXNRD2; thioredoxin reductase 2
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2549 GAB1; GRB2 associated binding protein 1
71 ACTG1; actin gamma 1
60 ACTB; actin beta
86 ACTL6A; actin like 6A
51412 ACTL6B; actin like 6B
6602 SMARCD1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
6603 SMARCD2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
6604 SMARCD3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
55274 PHF10; PHD finger protein 10
8193 DPF1; double PHD fingers 1
8110 DPF3; double PHD fingers 3
57492 ARID1B; AT-rich interaction domain 1B
8289 ARID1A; AT-rich interaction domain 1A
6605 SMARCE1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
6598 SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
6599 SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
6601 SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
6595 SMARCA2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
6597 SMARCA4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
196528 ARID2; AT-rich interaction domain 2
55193 PBRM1; polybromo 1
29117 BRD7; bromodomain containing 7
|
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04375 ELK1; ETS domain-containing protein Elk-1
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04377 MYC; Myc proto-oncogene protein
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K22197 BAF45A; BRG1-associated factor 45A
K22198 BAF45B_C; BRG1-associated factor 45B/C
K22198 BAF45B_C; BRG1-associated factor 45B/C
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1
K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C
K11649 SMARCC; SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]
K11765 ARID2; AT-rich interactive domain-containing protein 2
K11757 PBRM1; protein polybromo-1
K11723 BRD7; bromodomain-containing protein 7
|
05226 Gastric cancer [PATH:hsa05226]
|
1045 CDX2; caudal type homeobox 2
4583 MUC2; mucin 2, oligomeric mucus/gel-forming
1015 CDH17; cadherin 17
83998 REG4; regenerating family member 4
5243 ABCB1; ATP binding cassette subfamily B member 1
6469 SHH; sonic hedgehog signaling molecule
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
5915 RARB; retinoic acid receptor beta
6256 RXRA; retinoid X receptor alpha
6257 RXRB; retinoid X receptor beta
6258 RXRG; retinoid X receptor gamma
7471 WNT1; Wnt family member 1
7472 WNT2; Wnt family member 2
7482 WNT2B; Wnt family member 2B
7473 WNT3; Wnt family member 3
89780 WNT3A; Wnt family member 3A
54361 WNT4; Wnt family member 4
7474 WNT5A; Wnt family member 5A
81029 WNT5B; Wnt family member 5B
7475 WNT6; Wnt family member 6
7476 WNT7A; Wnt family member 7A
7477 WNT7B; Wnt family member 7B
7478 WNT8A; Wnt family member 8A
7479 WNT8B; Wnt family member 8B
7483 WNT9A; Wnt family member 9A
7484 WNT9B; Wnt family member 9B
7480 WNT10B; Wnt family member 10B
80326 WNT10A; Wnt family member 10A
7481 WNT11; Wnt family member 11
51384 WNT16; Wnt family member 16
8321 FZD1; frizzled class receptor 1
8324 FZD7; frizzled class receptor 7
2535 FZD2; frizzled class receptor 2
7976 FZD3; frizzled class receptor 3
8322 FZD4; frizzled class receptor 4
7855 FZD5; frizzled class receptor 5
8325 FZD8; frizzled class receptor 8
8323 FZD6; frizzled class receptor 6
11211 FZD10; frizzled class receptor 10
8326 FZD9; frizzled class receptor 9
4041 LRP5; LDL receptor related protein 5
4040 LRP6; LDL receptor related protein 6
1857 DVL3; dishevelled segment polarity protein 3
1856 DVL2; dishevelled segment polarity protein 2
1855 DVL1; dishevelled segment polarity protein 1
10023 FRAT1; FRAT regulator of WNT signaling pathway 1
23401 FRAT2; FRAT regulator of WNT signaling pathway 2
2932 GSK3B; glycogen synthase kinase 3 beta
8312 AXIN1; axin 1
8313 AXIN2; axin 2
324 APC; APC regulator of WNT signaling pathway
10297 APC2; APC regulator of WNT signaling pathway 2
1499 CTNNB1; catenin beta 1
122011 CSNK1A1L; casein kinase 1 alpha 1 like
1452 CSNK1A1; casein kinase 1 alpha 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
4609 MYC; MYC proto-oncogene, bHLH transcription factor
595 CCND1; cyclin D1
7015 TERT; telomerase reverse transcriptase
7012 TERC; telomerase RNA component
1950 EGF; epidermal growth factor
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
596 BCL2; BCL2 apoptosis regulator
4292 MLH1; mutL homolog 1
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
7046 TGFBR1; transforming growth factor beta receptor 1
7048 TGFBR2; transforming growth factor beta receptor 2
4087 SMAD2; SMAD family member 2
4088 SMAD3; SMAD family member 3
4089 SMAD4; SMAD family member 4
1030 CDKN2B; cyclin dependent kinase inhibitor 2B
999 CDH1; cadherin 1
29119 CTNNA3; catenin alpha 3
1495 CTNNA1; catenin alpha 1
1496 CTNNA2; catenin alpha 2
3728 JUP; junction plakoglobin
3082 HGF; hepatocyte growth factor
4233 MET; MET proto-oncogene, receptor tyrosine kinase
2246 FGF1; fibroblast growth factor 1
2247 FGF2; fibroblast growth factor 2
2248 FGF3; fibroblast growth factor 3
2249 FGF4; fibroblast growth factor 4
8822 FGF17; fibroblast growth factor 17
2251 FGF6; fibroblast growth factor 6
2252 FGF7; fibroblast growth factor 7
2253 FGF8; fibroblast growth factor 8
2254 FGF9; fibroblast growth factor 9
2255 FGF10; fibroblast growth factor 10
8823 FGF16; fibroblast growth factor 16
2250 FGF5; fibroblast growth factor 5
8817 FGF18; fibroblast growth factor 18
26281 FGF20; fibroblast growth factor 20
27006 FGF22; fibroblast growth factor 22
9965 FGF19; fibroblast growth factor 19
26291 FGF21; fibroblast growth factor 21
8074 FGF23; fibroblast growth factor 23
2263 FGFR2; fibroblast growth factor receptor 2
2549 GAB1; GRB2 associated binding protein 1
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K22234 CDX2; homeobox protein CDX2
K10955 MUC2; mucin-2
K06811 CDH17; cadherin 17, LI cadherin
K22244 REG4; regenerating islet-derived protein 4
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K11988 SHH; sonic hedgehog
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K08734 MLH1; DNA mismatch repair protein MLH1
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K05689 CDH1; cadherin 1, type 1, E-cadherin
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K10056 JUP; junction plakoglobin
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
|
05214 Glioma [PATH:hsa05214]
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1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
1956 EGFR; epidermal growth factor receptor
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
5335 PLCG1; phospholipase C gamma 1
5336 PLCG2; phospholipase C gamma 2
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
57118 CAMK1D; calcium/calmodulin dependent protein kinase ID
57172 CAMK1G; calcium/calmodulin dependent protein kinase IG
8536 CAMK1; calcium/calmodulin dependent protein kinase I
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
814 CAMK4; calcium/calmodulin dependent protein kinase IV
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2475 MTOR; mechanistic target of rapamycin kinase
5728 PTEN; phosphatase and tensin homolog
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
595 CCND1; cyclin D1
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
581 BAX; BCL2 associated X, apoptosis regulator
578 BAK1; BCL2 antagonist/killer 1
1643 DDB2; damage specific DNA binding protein 2
51426 POLK; DNA polymerase kappa
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
|
05216 Thyroid cancer [PATH:hsa05216]
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5979 RET; ret proto-oncogene
8030 CCDC6; coiled-coil domain containing 6
8031 NCOA4; nuclear receptor coactivator 4
4914 NTRK1; neurotrophic receptor tyrosine kinase 1
7170 TPM3; tropomyosin 3
7175 TPR; translocated promoter region, nuclear basket protein
10342 TFG; trafficking from ER to golgi regulator
3265 HRAS; HRas proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
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KEGG Orthology (KO) - Homo sapiens (human)