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KO |
09100 Metabolism
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09101 Carbohydrate metabolism
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09102 Energy metabolism
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09103 Lipid metabolism
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00061 Fatty acid biosynthesis [PATH:hsa00061]
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00062 Fatty acid elongation [PATH:hsa00062]
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00071 Fatty acid degradation [PATH:hsa00071]
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00073 Cutin, suberine and wax biosynthesis
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00100 Steroid biosynthesis [PATH:hsa00100]
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00120 Primary bile acid biosynthesis [PATH:hsa00120]
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00121 Secondary bile acid biosynthesis
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00140 Steroid hormone biosynthesis [PATH:hsa00140]
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1583 CYP11A1; cytochrome P450 family 11 subfamily A member 1
1586 CYP17A1; cytochrome P450 family 17 subfamily A member 1
412 STS; steroid sulfatase
6820 SULT2B1; sulfotransferase family 2B member 1
1589 CYP21A2; cytochrome P450 family 21 subfamily A member 2
3283 HSD3B1; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
3284 HSD3B2; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
6715 SRD5A1; steroid 5 alpha-reductase 1
6716 SRD5A2; steroid 5 alpha-reductase 2
79644 SRD5A3; steroid 5 alpha-reductase 3
1646 AKR1C2; aldo-keto reductase family 1 member C2
8644 AKR1C3; aldo-keto reductase family 1 member C3
1584 CYP11B1; cytochrome P450 family 11 subfamily B member 1
1585 CYP11B2; cytochrome P450 family 11 subfamily B member 2
6718 AKR1D1; aldo-keto reductase family 1 member D1
1109 AKR1C4; aldo-keto reductase family 1 member C4
3290 HSD11B1; hydroxysteroid 11-beta dehydrogenase 1
374875 HSD11B1L; hydroxysteroid 11-beta dehydrogenase 1 like
3291 HSD11B2; hydroxysteroid 11-beta dehydrogenase 2
1645 AKR1C1; aldo-keto reductase family 1 member C1
9420 CYP7B1; cytochrome P450 family 7 subfamily B member 1
6783 SULT1E1; sulfotransferase family 1E member 1
3292 HSD17B1; hydroxysteroid 17-beta dehydrogenase 1
3294 HSD17B2; hydroxysteroid 17-beta dehydrogenase 2
8630 HSD17B6; hydroxysteroid 17-beta dehydrogenase 6
51478 HSD17B7; hydroxysteroid 17-beta dehydrogenase 7
7923 HSD17B8; hydroxysteroid 17-beta dehydrogenase 8
51144 HSD17B12; hydroxysteroid 17-beta dehydrogenase 12
79154 DHRS11; dehydrogenase/reductase 11
1543 CYP1A1; cytochrome P450 family 1 subfamily A member 1
1544 CYP1A2; cytochrome P450 family 1 subfamily A member 2
1577 CYP3A5; cytochrome P450 family 3 subfamily A member 5
1551 CYP3A7; cytochrome P450 family 3 subfamily A member 7
100861540 CYP3A7-CYP3A51P; CYP3A7-CYP3A51P readthrough
1571 CYP2E1; cytochrome P450 family 2 subfamily E member 1
1576 CYP3A4; cytochrome P450 family 3 subfamily A member 4
1545 CYP1B1; cytochrome P450 family 1 subfamily B member 1
1588 CYP19A1; cytochrome P450 family 19 subfamily A member 1
1581 CYP7A1; cytochrome P450 family 7 subfamily A member 1
51170 HSD17B11; hydroxysteroid 17-beta dehydrogenase 11
10941 UGT2A1; UDP glucuronosyltransferase family 2 member A1 complex locus
79799 UGT2A3; UDP glucuronosyltransferase family 2 member A3
7367 UGT2B17; UDP glucuronosyltransferase family 2 member B17
10720 UGT2B11; UDP glucuronosyltransferase family 2 member B11
54490 UGT2B28; UDP glucuronosyltransferase family 2 member B28
54578 UGT1A6; UDP glucuronosyltransferase family 1 member A6
54657 UGT1A4; UDP glucuronosyltransferase family 1 member A4
54658 UGT1A1; UDP glucuronosyltransferase family 1 member A1
54659 UGT1A3; UDP glucuronosyltransferase family 1 member A3
7365 UGT2B10; UDP glucuronosyltransferase family 2 member B10
54600 UGT1A9; UDP glucuronosyltransferase family 1 member A9
7364 UGT2B7; UDP glucuronosyltransferase family 2 member B7
54575 UGT1A10; UDP glucuronosyltransferase family 1 member A10
54576 UGT1A8; UDP glucuronosyltransferase family 1 member A8
54579 UGT1A5; UDP glucuronosyltransferase family 1 member A5
7366 UGT2B15; UDP glucuronosyltransferase family 2 member B15
54577 UGT1A7; UDP glucuronosyltransferase family 1 member A7
7363 UGT2B4; UDP glucuronosyltransferase family 2 member B4
574537 UGT2A2; UDP glucuronosyltransferase family 2 member A2
1312 COMT; catechol-O-methyltransferase
220074 LRTOMT; leucine rich transmembrane and O-methyltransferase domain containing
3293 HSD17B3; hydroxysteroid 17-beta dehydrogenase 3
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K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K01131 STS; steryl-sulfatase [EC:3.1.6.2]
K01015 SULT2B; alcohol sulfotransferase [EC:2.8.2.2]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K12343 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:1.3.1.22 1.3.1.94]
K00089 AKR1C2; 3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K07433 CYP11B2; steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
K00251 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
K00037 AKR1C4; 3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00071 HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
K00212 AKR1C1; 20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K07430 CYP7B; 25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]
K01016 SULT1E1; estrone sulfotransferase [EC:2.8.2.4]
K00044 HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
K13368 HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K13369 HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13373 HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K13370 HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K22970 DHRS11; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K17690 CYP3A5; cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]
K17691 CYP3A7; cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
K17691 CYP3A7; cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K17689 CYP3A4; cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07434 CYP19A; aromatase [EC:1.14.14.14]
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K25779 HSD17B11; hydroxysteroid 17beta dehydrogenase 11 [EC:1.1.1.-]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
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00561 Glycerolipid metabolism [PATH:hsa00561]
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00564 Glycerophospholipid metabolism [PATH:hsa00564]
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00565 Ether lipid metabolism [PATH:hsa00565]
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00600 Sphingolipid metabolism [PATH:hsa00600]
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00590 Arachidonic acid metabolism [PATH:hsa00590]
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00591 Linoleic acid metabolism [PATH:hsa00591]
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00592 alpha-Linolenic acid metabolism [PATH:hsa00592]
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01040 Biosynthesis of unsaturated fatty acids [PATH:hsa01040]
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09104 Nucleotide metabolism
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09161 Cancer: overview
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09162 Cancer: specific types
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05210 Colorectal cancer [PATH:hsa05210]
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05212 Pancreatic cancer [PATH:hsa05212]
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05225 Hepatocellular carcinoma [PATH:hsa05225]
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05226 Gastric cancer [PATH:hsa05226]
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05214 Glioma [PATH:hsa05214]
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05216 Thyroid cancer [PATH:hsa05216]
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05221 Acute myeloid leukemia [PATH:hsa05221]
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05220 Chronic myeloid leukemia [PATH:hsa05220]
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05217 Basal cell carcinoma [PATH:hsa05217]
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05218 Melanoma [PATH:hsa05218]
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05211 Renal cell carcinoma [PATH:hsa05211]
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05219 Bladder cancer [PATH:hsa05219]
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05215 Prostate cancer [PATH:hsa05215]
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2950 GSTP1; glutathione S-transferase pi 1
1027 CDKN1B; cyclin dependent kinase inhibitor 1B
1017 CDK2; cyclin dependent kinase 2
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
5925 RB1; RB transcriptional corepressor 1
1869 E2F1; E2F transcription factor 1
1870 E2F2; E2F transcription factor 2
1871 E2F3; E2F transcription factor 3
7113 TMPRSS2; transmembrane serine protease 2
2078 ERG; ETS transcription factor ERG
5328 PLAU; plasminogen activator, urokinase
5327 PLAT; plasminogen activator, tissue type
4314 MMP3; matrix metallopeptidase 3
4318 MMP9; matrix metallopeptidase 9
6935 ZEB1; zinc finger E-box binding homeobox 1
7850 IL1R2; interleukin 1 receptor type 2
6692 SPINT1; serine peptidase inhibitor, Kunitz type 1
2119 ETV5; ETS variant transcription factor 5
3630 INS; insulin
5154 PDGFA; platelet derived growth factor subunit A
5155 PDGFB; platelet derived growth factor subunit B
56034 PDGFC; platelet derived growth factor C
80310 PDGFD; platelet derived growth factor D
1950 EGF; epidermal growth factor
7039 TGFA; transforming growth factor alpha
3479 IGF1; insulin like growth factor 1
3645 INSRR; insulin receptor related receptor
5156 PDGFRA; platelet derived growth factor receptor alpha
5159 PDGFRB; platelet derived growth factor receptor beta
2260 FGFR1; fibroblast growth factor receptor 1
2263 FGFR2; fibroblast growth factor receptor 2
1956 EGFR; epidermal growth factor receptor
2064 ERBB2; erb-b2 receptor tyrosine kinase 2
3480 IGF1R; insulin like growth factor 1 receptor
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5728 PTEN; phosphatase and tensin homolog
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
4824 NKX3-1; NK3 homeobox 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
842 CASP9; caspase 9
572 BAD; BCL2 associated agonist of cell death
2308 FOXO1; forkhead box O1
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
4193 MDM2; MDM2 proto-oncogene
7157 TP53; tumor protein p53
2932 GSK3B; glycogen synthase kinase 3 beta
1385 CREB1; cAMP responsive element binding protein 1
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1499 CTNNB1; catenin beta 1
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
595 CCND1; cyclin D1
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
596 BCL2; BCL2 apoptosis regulator
2475 MTOR; mechanistic target of rapamycin kinase
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
6716 SRD5A2; steroid 5 alpha-reductase 2
367 AR; androgen receptor
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
7184 HSP90B1; heat shock protein 90 beta family member 1
354 KLK3; kallikrein related peptidase 3
|
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
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05213 Endometrial cancer [PATH:hsa05213]
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05224 Breast cancer [PATH:hsa05224]
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05222 Small cell lung cancer [PATH:hsa05222]
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05223 Non-small cell lung cancer [PATH:hsa05223]
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
|
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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