KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:hsa00061]
     00062 Fatty acid elongation [PATH:hsa00062]
     00071 Fatty acid degradation [PATH:hsa00071]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:hsa00100]
     00120 Primary bile acid biosynthesis [PATH:hsa00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:hsa00140]
       1583 CYP11A1; cytochrome P450 family 11 subfamily A member 1
       1586 CYP17A1; cytochrome P450 family 17 subfamily A member 1
       412 STS; steroid sulfatase
       6820 SULT2B1; sulfotransferase family 2B member 1
       1589 CYP21A2; cytochrome P450 family 21 subfamily A member 2
       3283 HSD3B1; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
       3284 HSD3B2; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
       6715 SRD5A1; steroid 5 alpha-reductase 1
       6716 SRD5A2; steroid 5 alpha-reductase 2
       79644 SRD5A3; steroid 5 alpha-reductase 3
       1646 AKR1C2; aldo-keto reductase family 1 member C2
       8644 AKR1C3; aldo-keto reductase family 1 member C3
       1584 CYP11B1; cytochrome P450 family 11 subfamily B member 1
       1585 CYP11B2; cytochrome P450 family 11 subfamily B member 2
       6718 AKR1D1; aldo-keto reductase family 1 member D1
       1109 AKR1C4; aldo-keto reductase family 1 member C4
       3290 HSD11B1; hydroxysteroid 11-beta dehydrogenase 1
       374875 HSD11B1L; hydroxysteroid 11-beta dehydrogenase 1 like
       3291 HSD11B2; hydroxysteroid 11-beta dehydrogenase 2
       1645 AKR1C1; aldo-keto reductase family 1 member C1
       9420 CYP7B1; cytochrome P450 family 7 subfamily B member 1
       6783 SULT1E1; sulfotransferase family 1E member 1
       3292 HSD17B1; hydroxysteroid 17-beta dehydrogenase 1
       3294 HSD17B2; hydroxysteroid 17-beta dehydrogenase 2
       8630 HSD17B6; hydroxysteroid 17-beta dehydrogenase 6
       51478 HSD17B7; hydroxysteroid 17-beta dehydrogenase 7
       7923 HSD17B8; hydroxysteroid 17-beta dehydrogenase 8
       51144 HSD17B12; hydroxysteroid 17-beta dehydrogenase 12
       79154 DHRS11; dehydrogenase/reductase 11
       1543 CYP1A1; cytochrome P450 family 1 subfamily A member 1
       1544 CYP1A2; cytochrome P450 family 1 subfamily A member 2
       1577 CYP3A5; cytochrome P450 family 3 subfamily A member 5
       1551 CYP3A7; cytochrome P450 family 3 subfamily A member 7
       100861540 CYP3A7-CYP3A51P; CYP3A7-CYP3A51P readthrough
       1571 CYP2E1; cytochrome P450 family 2 subfamily E member 1
       1576 CYP3A4; cytochrome P450 family 3 subfamily A member 4
       1545 CYP1B1; cytochrome P450 family 1 subfamily B member 1
       1588 CYP19A1; cytochrome P450 family 19 subfamily A member 1
       1581 CYP7A1; cytochrome P450 family 7 subfamily A member 1
       51170 HSD17B11; hydroxysteroid 17-beta dehydrogenase 11
       10941 UGT2A1; UDP glucuronosyltransferase family 2 member A1 complex locus
       79799 UGT2A3; UDP glucuronosyltransferase family 2 member A3
       7367 UGT2B17; UDP glucuronosyltransferase family 2 member B17
       10720 UGT2B11; UDP glucuronosyltransferase family 2 member B11
       54490 UGT2B28; UDP glucuronosyltransferase family 2 member B28
       54578 UGT1A6; UDP glucuronosyltransferase family 1 member A6
       54657 UGT1A4; UDP glucuronosyltransferase family 1 member A4
       54658 UGT1A1; UDP glucuronosyltransferase family 1 member A1
       54659 UGT1A3; UDP glucuronosyltransferase family 1 member A3
       7365 UGT2B10; UDP glucuronosyltransferase family 2 member B10
       54600 UGT1A9; UDP glucuronosyltransferase family 1 member A9
       7364 UGT2B7; UDP glucuronosyltransferase family 2 member B7
       54575 UGT1A10; UDP glucuronosyltransferase family 1 member A10
       54576 UGT1A8; UDP glucuronosyltransferase family 1 member A8
       54579 UGT1A5; UDP glucuronosyltransferase family 1 member A5
       7366 UGT2B15; UDP glucuronosyltransferase family 2 member B15
       54577 UGT1A7; UDP glucuronosyltransferase family 1 member A7
       7363 UGT2B4; UDP glucuronosyltransferase family 2 member B4
       574537 UGT2A2; UDP glucuronosyltransferase family 2 member A2
       1312 COMT; catechol-O-methyltransferase
       220074 LRTOMT; leucine rich transmembrane and O-methyltransferase domain containing
       3293 HSD17B3; hydroxysteroid 17-beta dehydrogenase 3
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K01131 STS; steryl-sulfatase [EC:3.1.6.2]
K01015 SULT2B; alcohol sulfotransferase [EC:2.8.2.2]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K12343 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:1.3.1.22 1.3.1.94]
K00089 AKR1C2; 3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K07433 CYP11B2; steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
K00251 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
K00037 AKR1C4; 3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00071 HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
K00212 AKR1C1; 20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K07430 CYP7B; 25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]
K01016 SULT1E1; estrone sulfotransferase [EC:2.8.2.4]
K00044 HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
K13368 HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K13369 HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13373 HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K13370 HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K22970 DHRS11; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K17690 CYP3A5; cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]
K17691 CYP3A7; cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
K17691 CYP3A7; cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K17689 CYP3A4; cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07434 CYP19A; aromatase [EC:1.14.14.14]
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K25779 HSD17B11; hydroxysteroid 17beta dehydrogenase 11 [EC:1.1.1.-]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
     00561 Glycerolipid metabolism [PATH:hsa00561]
     00564 Glycerophospholipid metabolism [PATH:hsa00564]
     00565 Ether lipid metabolism [PATH:hsa00565]
     00600 Sphingolipid metabolism [PATH:hsa00600]
     00590 Arachidonic acid metabolism [PATH:hsa00590]
     00591 Linoleic acid metabolism [PATH:hsa00591]
     00592 alpha-Linolenic acid metabolism [PATH:hsa00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:hsa01040]
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:hsa05210]
     05212 Pancreatic cancer [PATH:hsa05212]
     05225 Hepatocellular carcinoma [PATH:hsa05225]
     05226 Gastric cancer [PATH:hsa05226]
     05214 Glioma [PATH:hsa05214]
     05216 Thyroid cancer [PATH:hsa05216]
     05221 Acute myeloid leukemia [PATH:hsa05221]
     05220 Chronic myeloid leukemia [PATH:hsa05220]
     05217 Basal cell carcinoma [PATH:hsa05217]
     05218 Melanoma [PATH:hsa05218]
     05211 Renal cell carcinoma [PATH:hsa05211]
     05219 Bladder cancer [PATH:hsa05219]
     05215 Prostate cancer [PATH:hsa05215]
       2950 GSTP1; glutathione S-transferase pi 1
       1027 CDKN1B; cyclin dependent kinase inhibitor 1B
       1017 CDK2; cyclin dependent kinase 2
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       5925 RB1; RB transcriptional corepressor 1
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       7113 TMPRSS2; transmembrane serine protease 2
       2078 ERG; ETS transcription factor ERG
       5328 PLAU; plasminogen activator, urokinase
       5327 PLAT; plasminogen activator, tissue type
       4314 MMP3; matrix metallopeptidase 3
       4318 MMP9; matrix metallopeptidase 9
       6935 ZEB1; zinc finger E-box binding homeobox 1
       7850 IL1R2; interleukin 1 receptor type 2
       6692 SPINT1; serine peptidase inhibitor, Kunitz type 1
       2119 ETV5; ETS variant transcription factor 5
       3630 INS; insulin
       5154 PDGFA; platelet derived growth factor subunit A
       5155 PDGFB; platelet derived growth factor subunit B
       56034 PDGFC; platelet derived growth factor C
       80310 PDGFD; platelet derived growth factor D
       1950 EGF; epidermal growth factor
       7039 TGFA; transforming growth factor alpha
       3479 IGF1; insulin like growth factor 1
       3645 INSRR; insulin receptor related receptor
       5156 PDGFRA; platelet derived growth factor receptor alpha
       5159 PDGFRB; platelet derived growth factor receptor beta
       2260 FGFR1; fibroblast growth factor receptor 1
       2263 FGFR2; fibroblast growth factor receptor 2
       1956 EGFR; epidermal growth factor receptor
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       3480 IGF1R; insulin like growth factor 1 receptor
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5728 PTEN; phosphatase and tensin homolog
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       4824 NKX3-1; NK3 homeobox 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       842 CASP9; caspase 9
       572 BAD; BCL2 associated agonist of cell death
       2308 FOXO1; forkhead box O1
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       4193 MDM2; MDM2 proto-oncogene
       7157 TP53; tumor protein p53
       2932 GSK3B; glycogen synthase kinase 3 beta
       1385 CREB1; cAMP responsive element binding protein 1
       468 ATF4; activating transcription factor 4
       10488 CREB3; cAMP responsive element binding protein 3
       90993 CREB3L1; cAMP responsive element binding protein 3 like 1
       64764 CREB3L2; cAMP responsive element binding protein 3 like 2
       84699 CREB3L3; cAMP responsive element binding protein 3 like 3
       148327 CREB3L4; cAMP responsive element binding protein 3 like 4
       9586 CREB5; cAMP responsive element binding protein 5
       1499 CTNNB1; catenin beta 1
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       595 CCND1; cyclin D1
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       596 BCL2; BCL2 apoptosis regulator
       2475 MTOR; mechanistic target of rapamycin kinase
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       6716 SRD5A2; steroid 5 alpha-reductase 2
       367 AR; androgen receptor
       3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
       3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
       7184 HSP90B1; heat shock protein 90 beta family member 1
       354 KLK3; kallikrein related peptidase 3
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
     05213 Endometrial cancer [PATH:hsa05213]
     05224 Breast cancer [PATH:hsa05224]
     05222 Small cell lung cancer [PATH:hsa05222]
     05223 Non-small cell lung cancer [PATH:hsa05223]
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 18, 2024