| |
KO |
 09100 Metabolism
|
|
|
09120 Genetic Information Processing
|
|
|
09130 Environmental Information Processing
|
|
|
09140 Cellular Processes
|
|
|
 09150 Organismal Systems
|
|
|
09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:hsa04640]
|
04610 Complement and coagulation cascades [PATH:hsa04610]
|
04611 Platelet activation [PATH:hsa04611]
|
04613 Neutrophil extracellular trap formation [PATH:hsa04613]
|
04620 Toll-like receptor signaling pathway [PATH:hsa04620]
|
 04624 Toll and Imd signaling pathway
|
04621 NOD-like receptor signaling pathway [PATH:hsa04621]
|
04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
|
23586 RIGI; RNA sensor RIG-I
64135 IFIH1; interferon induced with helicase C domain 1
57169 ZNFX1; zinc finger NFX1-type containing 1
57506 MAVS; mitochondrial antiviral signaling protein
79132 DHX58; DExH-box helicase 58
7187 TRAF3; TNF receptor associated factor 3
10010 TANK; TRAF family member associated NFKB activator
64343 AZI2; 5-azacytidine induced 2
9755 TBKBP1; TBK1 binding protein 1
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
29110 TBK1; TANK binding kinase 1
9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
3661 IRF3; interferon regulatory factor 3
3665 IRF7; interferon regulatory factor 7
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
3467 IFNW1; interferon omega 1
338376 IFNE; interferon epsilon
56832 IFNK; interferon kappa
8717 TRADD; TNFRSF1A associated via death domain
8772 FADD; Fas associated via death domain
8737 RIPK1; receptor interacting serine/threonine kinase 1
841 CASP8; caspase 8
843 CASP10; caspase 10
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
4793 NFKBIB; NFKB inhibitor beta
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
7186 TRAF2; TNF receptor associated factor 2
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
7189 TRAF6; TNF receptor associated factor 6
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
3576 CXCL8; C-X-C motif chemokine ligand 8
7124 TNF; tumor necrosis factor
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3627 CXCL10; C-X-C motif chemokine ligand 10
103 ADAR; adenosine deaminase RNA specific
7706 TRIM25; tripartite motif containing 25
1540 CYLD; CYLD lysine 63 deubiquitinase
54941 RNF125; ring finger protein 125
9636 ISG15; ISG15 ubiquitin like modifier
9474 ATG5; autophagy related 5
9140 ATG12; autophagy related 12
79671 NLRX1; NLR family member X1
340061 STING1; stimulator of interferon response cGAMP interactor 1
55593 OTUD5; OTU deubiquitinase 5
80143 SIKE1; suppressor of IKBKE 1
1654 DDX3X; DEAD-box helicase 3 X-linked
5300 PIN1; peptidylprolyl cis/trans isomerase, NIMA-interacting 1
26007 TKFC; triokinase and FMN cyclase
|
K12646 RIGI; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K27391 ZNFX1; NFX1-type zinc finger-containing protein 1
K12648 MAVS; mitochondrial antiviral-signaling protein
K12649 DHX58; ATP-dependent RNA helicase DHX58 [EC:5.6.2.6]
K03174 TRAF3; TNF receptor-associated factor 3
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K12651 AZI2; 5-azacytidine-induced protein 2
K12652 TBKBP1; TANK-binding kinase 1-binding protein
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10030 IL8; interleukin 8
K03156 TNF; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K12671 CXCL10; C-X-C motif chemokine 10
K12968 ADAR; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
K12159 ISG15; ubiquitin cross-reactive protein
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K12653 NLRX1; NLR family member X1
K12654 STING1; stimulator of interferon genes protein
K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
K12656 SIKE; suppressor of IKK-epsilon
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
K00863 DAK; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]
|
04623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
|
04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
|
04650 Natural killer cell mediated cytotoxicity [PATH:hsa04650]
|
04612 Antigen processing and presentation [PATH:hsa04612]
|
04660 T cell receptor signaling pathway [PATH:hsa04660]
|
04658 Th1 and Th2 cell differentiation [PATH:hsa04658]
|
04659 Th17 cell differentiation [PATH:hsa04659]
|
04657 IL-17 signaling pathway [PATH:hsa04657]
|
04662 B cell receptor signaling pathway [PATH:hsa04662]
|
04664 Fc epsilon RI signaling pathway [PATH:hsa04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:hsa04666]
|
04670 Leukocyte transendothelial migration [PATH:hsa04670]
|
04672 Intestinal immune network for IgA production [PATH:hsa04672]
|
04062 Chemokine signaling pathway [PATH:hsa04062]
|
|
|
09152 Endocrine system
|
|
|
09153 Circulatory system
|
|
|
09154 Digestive system
|
|
|
09155 Excretory system
|
|
|
09156 Nervous system
|
|
|
09157 Sensory system
|
|
|
09158 Development and regeneration
|
|
|
09149 Aging
|
|
|
09159 Environmental adaptation
|
|
|
09160 Human Diseases
|
|
|
09180 Brite Hierarchies
|
|
|
09181 Protein families: metabolism
|
|
|
09182 Protein families: genetic information processing
|
|
|
09183 Protein families: signaling and cellular processes
|
02000 Transporters [BR:hsa02000]
|
02044 Secretion system [BR:hsa02044]
|
02042 Bacterial toxins [BR:hsa02042]
|
02022 Two-component system
|
02035 Bacterial motility proteins
|
03037 Cilium and associated proteins [BR:hsa03037]
|
04812 Cytoskeleton proteins [BR:hsa04812]
|
04147 Exosome [BR:hsa04147]
|
02048 Prokaryotic defense system [BR:hsa02048]
|
04030 G protein-coupled receptors [BR:hsa04030]
|
04050 Cytokine receptors [BR:hsa04050]
|
04054 Pattern recognition receptors [BR:hsa04054]
|
7096 TLR1; toll like receptor 1
7097 TLR2; toll like receptor 2
7098 TLR3; toll like receptor 3
7099 TLR4; toll like receptor 4
7100 TLR5; toll like receptor 5
10333 TLR6; toll like receptor 6
51284 TLR7; toll like receptor 7
51311 TLR8; toll like receptor 8
54106 TLR9; toll like receptor 9
81793 TLR10; toll like receptor 10
51267 CLEC1A; C-type lectin domain family 1 member A
51266 CLEC1B; C-type lectin domain family 1 member B
9976 CLEC2B; C-type lectin domain family 2 member B
29121 CLEC2D; C-type lectin domain family 2 member D
50856 CLEC4A; C-type lectin domain family 4 member A
170482 CLEC4C; C-type lectin domain family 4 member C
338339 CLEC4D; C-type lectin domain family 4 member D
26253 CLEC4E; C-type lectin domain family 4 member E
339390 CLEC4G; C-type lectin domain family 4 member G
10332 CLEC4M; C-type lectin domain family 4 member M
30835 CD209; CD209 molecule
23601 CLEC5A; C-type lectin domain containing 5A
93978 CLEC6A; C-type lectin domain containing 6A
64581 CLEC7A; C-type lectin domain containing 7A
283420 CLEC9A; C-type lectin domain containing 9A
10462 CLEC10A; C-type lectin domain containing 10A
160364 CLEC12A; C-type lectin domain family 12 member A
387837 CLEC12B; C-type lectin domain family 12 member B
4065 LY75; lymphocyte antigen 75
100526664 LY75-CD302; LY75-CD302 readthrough
22925 PLA2R1; phospholipase A2 receptor 1
4360 MRC1; mannose receptor C-type 1
9902 MRC2; mannose receptor C type 2
50489 CD207; CD207 molecule
4973 OLR1; oxidized low density lipoprotein receptor 1
10392 NOD1; nucleotide binding oligomerization domain containing 1
64127 NOD2; nucleotide binding oligomerization domain containing 2
197358 NLRC3; NLR family CARD domain containing 3
58484 NLRC4; NLR family CARD domain containing 4
84166 NLRC5; NLR family CARD domain containing 5
79671 NLRX1; NLR family member X1
4261 CIITA; class II major histocompatibility complex transactivator
4671 NAIP; NLR family apoptosis inhibitory protein
22861 NLRP1; NLR family pyrin domain containing 1
55655 NLRP2; NLR family pyrin domain containing 2
114548 NLRP3; NLR family pyrin domain containing 3
147945 NLRP4; NLR family pyrin domain containing 4
126206 NLRP5; NLR family pyrin domain containing 5
171389 NLRP6; NLR family pyrin domain containing 6
199713 NLRP7; NLR family pyrin domain containing 7
126205 NLRP8; NLR family pyrin domain containing 8
338321 NLRP9; NLR family pyrin domain containing 9
338322 NLRP10; NLR family pyrin domain containing 10
204801 NLRP11; NLR family pyrin domain containing 11
91662 NLRP12; NLR family pyrin domain containing 12
126204 NLRP13; NLR family pyrin domain containing 13
338323 NLRP14; NLR family pyrin domain containing 14
23586 RIGI; RNA sensor RIG-I
64135 IFIH1; interferon induced with helicase C domain 1
79132 DHX58; DExH-box helicase 58
|
K05398 TLR1; toll-like receptor 1
K10159 TLR2; toll-like receptor 2
K05401 TLR3; toll-like receptor 3
K10160 TLR4; toll-like receptor 4
K10168 TLR5; toll-like receptor 5
K10169 TLR6; toll-like receptor 6
K05404 TLR7; toll-like receptor 7
K10170 TLR8; toll-like receptor 8
K10161 TLR9; toll-like receptor 9
K10171 TLR10; toll-like receptor 10
K10069 CLEC1A; C-type lectin domain family 1 member A
K10070 CLEC1B; C-type lectin domain family 1 member B
K10071 CLEC2B; C-type lectin domain family 2 member B
K10072 CLEC2D; C-type lectin domain family 2 member D
K10057 CLEC4A; C-type lectin domain family 4 member A
K06723 CLEC4C; C-type lectin domain family 4 member C
K10058 CLEC4D; C-type lectin domain family 4 member D
K10059 CLEC4E; C-type lectin domain family 4 member E
K10061 CLEC4G; C-type lectin superfamily 4 member G
K06563 CLEC4L_M; C-type lectin domain family 4 member L/M
K06563 CLEC4L_M; C-type lectin domain family 4 member L/M
K10073 CLEC5A; C-type lectin domain family 5 member A
K17514 CLEC6A; C-type lectin domain family 6 member A
K10074 CLEC7A; C-type lectin domain family 7 member A
K17515 CLEC9A; C-type lectin domain family 9 member A
K06721 CLEC10A; C-type lectin domain family 10 member A
K17516 CLEC12A; C-type lectin domain family 12 member A
K17517 CLEC12B; C-type lectin domain family 12 member B
K06559 LY75; lymphocyte antigen 75
K06559 LY75; lymphocyte antigen 75
K06560 MRC; mannose receptor, C type
K06560 MRC; mannose receptor, C type
K06560 MRC; mannose receptor, C type
K06561 CD207; CD207 antigen
K08763 OLR1; oxidised low-density lipoprotein receptor 1
K08727 NOD1; nucleotide-binding oligomerization domain-containing protein 1
K10165 NOD2; nucleotide-binding oligomerization domain-containing protein 2
K22614 NLRC3; NLR family CARD domain-containing protein 3
K12805 NLRC4; NLR family CARD domain-containing protein 4
K22615 NLRC5; NLR family CARD domain containing 5
K12653 NLRX1; NLR family member X1
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K12807 NAIP; baculoviral IAP repeat-containing protein 1
K12798 NLRP1; NACHT, LRR and PYD domains-containing protein 1
K19409 NLRP2; NACHT, LRR and PYD domains-containing protein 2
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K22265 NLRP4; NACHT, LRR and PYD domains-containing protein 4
K22626 NLRP5; NACHT, LRR and PYD domains-containing protein 5
K20863 NLRP6; NACHT, LRR and PYD domains-containing protein 6
K20864 NLRP7; NACHT, LRR and PYD domains-containing protein 7
K22662 NLRP8; NACHT, LRR and PYD domains-containing protein 8
K22663 NLRP9; NACHT, LRR and PYD domains-containing protein 9
K22266 NLRP10; NACHT, LRR and PYD domains-containing protein 10
K22664 NLRP11; NACHT, LRR and PYD domains-containing protein 11
K20865 NLRP12; NACHT, LRR and PYD domains-containing protein 12
K22665 NLRP13; NACHT, LRR and PYD domains-containing protein 13
K22666 NLRP14; NACHT, LRR and PYD domains-containing protein 14
K12646 RIGI; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K12649 DHX58; ATP-dependent RNA helicase DHX58 [EC:5.6.2.6]
|
03310 Nuclear receptors [BR:hsa03310]
|
04040 Ion channels [BR:hsa04040]
|
04031 GTP-binding proteins [BR:hsa04031]
|
04052 Cytokines and neuropeptides [BR:hsa04052]
|
04515 Cell adhesion molecules [BR:hsa04515]
|
04090 CD molecules [BR:hsa04090]
|
01504 Antimicrobial resistance genes
|
00535 Proteoglycans [BR:hsa00535]
|
00536 Glycosaminoglycan binding proteins [BR:hsa00536]
|
00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
|
04091 Lectins [BR:hsa04091]
|
04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
|
|
|
09185 Viral protein families
|
|
|
09184 RNA family
|
|
|
09190 Not Included in Pathway or Brite
|
KEGG Orthology (KO) - Homo sapiens (human)