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KO |
 09100 Metabolism
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 09101 Carbohydrate metabolism
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09102 Energy metabolism
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09103 Lipid metabolism
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00061 Fatty acid biosynthesis [PATH:hsa00061]
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00062 Fatty acid elongation [PATH:hsa00062]
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00071 Fatty acid degradation [PATH:hsa00071]
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00073 Cutin, suberine and wax biosynthesis
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00100 Steroid biosynthesis [PATH:hsa00100]
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00120 Primary bile acid biosynthesis [PATH:hsa00120]
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 00121 Secondary bile acid biosynthesis
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00140 Steroid hormone biosynthesis [PATH:hsa00140]
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00561 Glycerolipid metabolism [PATH:hsa00561]
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00564 Glycerophospholipid metabolism [PATH:hsa00564]
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00565 Ether lipid metabolism [PATH:hsa00565]
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00600 Sphingolipid metabolism [PATH:hsa00600]
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10558 SPTLC1; serine palmitoyltransferase long chain base subunit 1
9517 SPTLC2; serine palmitoyltransferase long chain base subunit 2
55304 SPTLC3; serine palmitoyltransferase long chain base subunit 3
2531 KDSR; 3-ketodihydrosphingosine reductase
10715 CERS1; ceramide synthase 1
29956 CERS2; ceramide synthase 2
79603 CERS4; ceramide synthase 4
204219 CERS3; ceramide synthase 3
253782 CERS6; ceramide synthase 6
91012 CERS5; ceramide synthase 5
427 ASAH1; N-acylsphingosine amidohydrolase 1
56624 ASAH2; N-acylsphingosine amidohydrolase 2
340485 ACER2; alkaline ceramidase 2
125981 ACER1; alkaline ceramidase 1
55331 ACER3; alkaline ceramidase 3
8560 DEGS1; delta 4-desaturase, sphingolipid 1
123099 DEGS2; delta 4-desaturase, sphingolipid 2
259230 SGMS1; sphingomyelin synthase 1
166929 SGMS2; sphingomyelin synthase 2
6609 SMPD1; sphingomyelin phosphodiesterase 1
6610 SMPD2; sphingomyelin phosphodiesterase 2
55512 SMPD3; sphingomyelin phosphodiesterase 3
55627 SMPD4; sphingomyelin phosphodiesterase 4
339221 ENPP7; ectonucleotide pyrophosphatase/phosphodiesterase 7
64781 CERK; ceramide kinase
8611 PLPP1; phospholipid phosphatase 1
8613 PLPP3; phospholipid phosphatase 3
8612 PLPP2; phospholipid phosphatase 2
81537 SGPP1; sphingosine-1-phosphate phosphatase 1
130367 SGPP2; sphingosine-1-phosphate phosphatase 2
8877 SPHK1; sphingosine kinase 1
56848 SPHK2; sphingosine kinase 2
8879 SGPL1; sphingosine-1-phosphate lyase 1
7357 UGCG; UDP-glucose ceramide glucosyltransferase
2629 GBA1; glucosylceramidase beta 1
57704 GBA2; glucosylceramidase beta 2
9331 B4GALT6; beta-1,4-galactosyltransferase 6
9334 B4GALT5; beta-1,4-galactosyltransferase 5
2720 GLB1; galactosidase beta 1
7368 UGT8; UDP glycosyltransferase 8
2581 GALC; galactosylceramidase
9514 GAL3ST1; galactose-3-O-sulfotransferase 1
410 ARSA; arylsulfatase A
4758 NEU1; neuraminidase 1
10825 NEU3; neuraminidase 3
129807 NEU4; neuraminidase 4
4759 NEU2; neuraminidase 2
2717 GLA; galactosidase alpha
2583 B4GALNT1; beta-1,4-N-acetyl-galactosaminyltransferase 1
3073 HEXA; hexosaminidase subunit alpha
3074 HEXB; hexosaminidase subunit beta
2760 GM2A; ganglioside GM2 activator
5660 PSAP; prosaposin
768239 PSAPL1; prosaposin like 1
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K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K04708 KDSR; 3-dehydrosphinganine reductase [EC:1.1.1.102]
K04710 CERS1; sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24622 CERS3; very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K12349 ASAH2; neutral ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K04711 ACER3; dihydroceramidase [EC:3.5.1.-]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K12350 SMPD1; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K12351 SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
K12352 SMPD3; sphingomyelin phosphodiesterase 3 [EC:3.1.4.12]
K12353 SMPD4; sphingomyelin phosphodiesterase 4 [EC:3.1.4.12]
K12354 ENPP7; ectonucleotide pyrophosphatase/phosphodiesterase family member 7 [EC:3.1.4.12]
K04715 CERK; ceramide kinase [EC:2.7.1.138]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K04716 SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
K04717 SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K01634 SGPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
K00720 UGCG; ceramide glucosyltransferase [EC:2.4.1.80]
K01201 GBA; glucosylceramidase [EC:3.2.1.45]
K17108 GBA2; non-lysosomal glucosylceramidase [EC:3.2.1.45]
K07553 B4GALT6; beta-1,4-galactosyltransferase 6 [EC:2.4.1.274]
K09905 B4GALT5; beta-1,4-galactosyltransferase 5 [EC:2.4.1.274 2.4.1.-]
K12309 GLB1; beta-galactosidase [EC:3.2.1.23]
K04628 CGT; ceramide galactosyltransferase [EC:2.4.1.47]
K01202 GALC; galactosylceramidase [EC:3.2.1.46]
K01019 GAL3ST1; galactosylceramide sulfotransferase [EC:2.8.2.11]
K01134 ARSA; arylsulfatase A [EC:3.1.6.8]
K01186 NEU1; sialidase-1 [EC:3.2.1.18]
K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
K01189 GLA; alpha-galactosidase [EC:3.2.1.22]
K00725 B4GALNT1; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase [EC:2.4.1.92]
K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
K12383 GM2A; ganglioside GM2 activator
K12382 PSAP; saposin
K12382 PSAP; saposin
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00590 Arachidonic acid metabolism [PATH:hsa00590]
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00591 Linoleic acid metabolism [PATH:hsa00591]
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00592 alpha-Linolenic acid metabolism [PATH:hsa00592]
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01040 Biosynthesis of unsaturated fatty acids [PATH:hsa01040]
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09104 Nucleotide metabolism
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system
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04010 MAPK signaling pathway [PATH:hsa04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:hsa04012]
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04014 Ras signaling pathway [PATH:hsa04014]
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04015 Rap1 signaling pathway [PATH:hsa04015]
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04310 Wnt signaling pathway [PATH:hsa04310]
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04330 Notch signaling pathway [PATH:hsa04330]
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04340 Hedgehog signaling pathway [PATH:hsa04340]
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:hsa04350]
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04390 Hippo signaling pathway [PATH:hsa04390]
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04391 Hippo signaling pathway - fly
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04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
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04370 VEGF signaling pathway [PATH:hsa04370]
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04371 Apelin signaling pathway [PATH:hsa04371]
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04630 JAK-STAT signaling pathway [PATH:hsa04630]
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04064 NF-kappa B signaling pathway [PATH:hsa04064]
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04668 TNF signaling pathway [PATH:hsa04668]
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04066 HIF-1 signaling pathway [PATH:hsa04066]
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04068 FoxO signaling pathway [PATH:hsa04068]
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04020 Calcium signaling pathway [PATH:hsa04020]
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04070 Phosphatidylinositol signaling system [PATH:hsa04070]
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04072 Phospholipase D signaling pathway [PATH:hsa04072]
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04071 Sphingolipid signaling pathway [PATH:hsa04071]
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10558 SPTLC1; serine palmitoyltransferase long chain base subunit 1
9517 SPTLC2; serine palmitoyltransferase long chain base subunit 2
55304 SPTLC3; serine palmitoyltransferase long chain base subunit 3
171546 SPTSSA; serine palmitoyltransferase small subunit A
165679 SPTSSB; serine palmitoyltransferase small subunit B
10715 CERS1; ceramide synthase 1
29956 CERS2; ceramide synthase 2
79603 CERS4; ceramide synthase 4
204219 CERS3; ceramide synthase 3
253782 CERS6; ceramide synthase 6
91012 CERS5; ceramide synthase 5
8560 DEGS1; delta 4-desaturase, sphingolipid 1
123099 DEGS2; delta 4-desaturase, sphingolipid 2
6609 SMPD1; sphingomyelin phosphodiesterase 1
259230 SGMS1; sphingomyelin synthase 1
166929 SGMS2; sphingomyelin synthase 2
7124 TNF; tumor necrosis factor
7132 TNFRSF1A; TNF receptor superfamily member 1A
8439 NSMAF; neutral sphingomyelinase activation associated factor
6610 SMPD2; sphingomyelin phosphodiesterase 2
427 ASAH1; N-acylsphingosine amidohydrolase 1
56624 ASAH2; N-acylsphingosine amidohydrolase 2
340485 ACER2; alkaline ceramidase 2
125981 ACER1; alkaline ceramidase 1
8717 TRADD; TNFRSF1A associated via death domain
7186 TRAF2; TNF receptor associated factor 2
1509 CTSD; cathepsin D
637 BID; BH3 interacting domain death agonist
581 BAX; BCL2 associated X, apoptosis regulator
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
5590 PRKCZ; protein kinase C zeta
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
596 BCL2; BCL2 apoptosis regulator
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
28227 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta
55012 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma
5523 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha
5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
7157 TP53; tumor protein p53
2205 FCER1A; Fc epsilon receptor Ia
2206 MS4A2; membrane spanning 4-domains A2
2207 FCER1G; Fc epsilon receptor Ig
2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
9846 GAB2; GRB2 associated binding protein 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5337 PLD1; phospholipase D1
5338 PLD2; phospholipase D2
8877 SPHK1; sphingosine kinase 1
56848 SPHK2; sphingosine kinase 2
3827 KNG1; kininogen 1
134 ADORA1; adenosine A1 receptor
140 ADORA3; adenosine A3 receptor
624 BDKRB2; bradykinin receptor B2
4985 OPRD1; opioid receptor delta 1
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
5581 PRKCE; protein kinase C epsilon
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
81537 SGPP1; sphingosine-1-phosphate phosphatase 1
130367 SGPP2; sphingosine-1-phosphate phosphatase 2
4363 ABCC1; ATP binding cassette subfamily C member 1 (ABCC1 blood group)
8879 SGPL1; sphingosine-1-phosphate lyase 1
1901 S1PR1; sphingosine-1-phosphate receptor 1
9294 S1PR2; sphingosine-1-phosphate receptor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
4846 NOS3; nitric oxide synthase 3
5879 RAC1; Rac family small GTPase 1
5880 RAC2; Rac family small GTPase 2
5881 RAC3; Rac family small GTPase 3
1903 S1PR3; sphingosine-1-phosphate receptor 3
2776 GNAQ; G protein subunit alpha q
5578 PRKCA; protein kinase C alpha
5579 PRKCB; protein kinase C beta
5582 PRKCG; protein kinase C gamma
8698 S1PR4; sphingosine-1-phosphate receptor 4
53637 S1PR5; sphingosine-1-phosphate receptor 5
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
5728 PTEN; phosphatase and tensin homolog
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
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K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K26384 SPTSS; serine palmitoyltransferase small subunit
K26384 SPTSS; serine palmitoyltransferase small subunit
K04710 CERS1; sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24622 CERS3; very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K12350 SMPD1; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K18953 NSMAF; factor associated with neutral sphingomyelinase activation
K12351 SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K12349 ASAH2; neutral ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04451 TP53; tumor protein p53
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K03898 KNG; kininogen
K04265 ADORA1; adenosine receptor A1
K04268 ADORA3; adenosine receptor A3
K03916 BDKRB2; bradykinin receptor B2
K04213 OPRD1; delta-type opioid receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04716 SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
K04717 SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K01634 SGPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04292 S1PR2; sphingosine 1-phosphate receptor 2
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04290 S1PR3; sphingosine 1-phosphate receptor 3
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K04295 S1PR5; sphingosine 1-phosphate receptor 5
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
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04024 cAMP signaling pathway [PATH:hsa04024]
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04022 cGMP-PKG signaling pathway [PATH:hsa04022]
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04151 PI3K-Akt signaling pathway [PATH:hsa04151]
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04152 AMPK signaling pathway [PATH:hsa04152]
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04150 mTOR signaling pathway [PATH:hsa04150]
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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01000 Enzymes [BR:hsa01000]
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01001 Protein kinases [BR:hsa01001]
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01009 Protein phosphatases and associated proteins [BR:hsa01009]
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01002 Peptidases and inhibitors [BR:hsa01002]
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01003 Glycosyltransferases [BR:hsa01003]
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01005 Lipopolysaccharide biosynthesis proteins
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01011 Peptidoglycan biosynthesis and degradation proteins
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01004 Lipid biosynthesis proteins [BR:hsa01004]
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2194 FASN; fatty acid synthase
27349 MCAT; malonyl-CoA-acyl carrier protein transacylase
54995 OXSM; 3-oxoacyl-ACP synthase, mitochondrial
51144 HSD17B12; hydroxysteroid 17-beta dehydrogenase 12
201562 HACD2; 3-hydroxyacyl-CoA dehydratase 2
9200 HACD1; 3-hydroxyacyl-CoA dehydratase 1
401494 HACD4; 3-hydroxyacyl-CoA dehydratase 4
51495 HACD3; 3-hydroxyacyl-CoA dehydratase 3
55825 PECR; peroxisomal trans-2-enoyl-CoA reductase
9524 TECR; trans-2,3-enoyl-CoA reductase
55301 OLAH; oleoyl-ACP hydrolase
5538 PPT1; palmitoyl-protein thioesterase 1
9374 PPT2; palmitoyl-protein thioesterase 2
122970 ACOT4; acyl-CoA thioesterase 4
10965 ACOT2; acyl-CoA thioesterase 2
641371 ACOT1; acyl-CoA thioesterase 1
641372 ACOT6; acyl-CoA thioesterase 6
11332 ACOT7; acyl-CoA thioesterase 7
23597 ACOT9; acyl-CoA thioesterase 9
26027 ACOT11; acyl-CoA thioesterase 11
55856 ACOT13; acyl-CoA thioesterase 13
6319 SCD; stearoyl-CoA desaturase
79966 SCD5; stearoyl-CoA desaturase 5
3995 FADS3; fatty acid desaturase 3
3992 FADS1; fatty acid desaturase 1
9415 FADS2; fatty acid desaturase 2
8560 DEGS1; delta 4-desaturase, sphingolipid 1
123099 DEGS2; delta 4-desaturase, sphingolipid 2
283985 FADS6; fatty acid desaturase 6
64834 ELOVL1; ELOVL fatty acid elongase 1
54898 ELOVL2; ELOVL fatty acid elongase 2
6785 ELOVL4; ELOVL fatty acid elongase 4
60481 ELOVL5; ELOVL fatty acid elongase 5
79071 ELOVL6; ELOVL fatty acid elongase 6
79993 ELOVL7; ELOVL fatty acid elongase 7
83401 ELOVL3; ELOVL fatty acid elongase 3
84532 ACSS1; acyl-CoA synthetase short chain family member 1
55902 ACSS2; acyl-CoA synthetase short chain family member 2
79611 ACSS3; acyl-CoA synthetase short chain family member 3
65985 AACS; acetoacetyl-CoA synthetase
116285 ACSM1; acyl-CoA synthetase medium chain family member 1
123876 ACSM2A; acyl-CoA synthetase medium chain family member 2A
341392 ACSM4; acyl-CoA synthetase medium chain family member 4
54988 ACSM5; acyl-CoA synthetase medium chain family member 5
6296 ACSM3; acyl-CoA synthetase medium chain family member 3
348158 ACSM2B; acyl-CoA synthetase medium chain family member 2B
142827 ACSM6; acyl-CoA synthetase medium chain family member 6
80221 ACSF2; acyl-CoA synthetase family member 2
23305 ACSL6; acyl-CoA synthetase long chain family member 6
2182 ACSL4; acyl-CoA synthetase long chain family member 4
2180 ACSL1; acyl-CoA synthetase long chain family member 1
51703 ACSL5; acyl-CoA synthetase long chain family member 5
2181 ACSL3; acyl-CoA synthetase long chain family member 3
23205 ACSBG1; acyl-CoA synthetase bubblegum family member 1
81616 ACSBG2; acyl-CoA synthetase bubblegum family member 2
376497 SLC27A1; solute carrier family 27 member 1
10999 SLC27A4; solute carrier family 27 member 4
11001 SLC27A2; solute carrier family 27 member 2
11000 SLC27A3; solute carrier family 27 member 3
132949 AASDH; aminoadipate-semialdehyde dehydrogenase
57678 GPAM; glycerol-3-phosphate acyltransferase, mitochondrial
150763 GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial
137964 GPAT4; glycerol-3-phosphate acyltransferase 4
84803 GPAT3; glycerol-3-phosphate acyltransferase 3
10554 AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1
10555 AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2
51099 ABHD5; abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
253558 LCLAT1; lysocardiolipin acyltransferase 1
6901 TAFAZZIN; tafazzin, phospholipid-lysophospholipid transacylase
154141 MBOAT1; membrane bound O-acyltransferase domain containing 1
129642 MBOAT2; membrane bound O-acyltransferase domain containing 2
56894 AGPAT3; 1-acylglycerol-3-phosphate O-acyltransferase 3
56895 AGPAT4; 1-acylglycerol-3-phosphate O-acyltransferase 4
54947 LPCAT2; lysophosphatidylcholine acyltransferase 2
79888 LPCAT1; lysophosphatidylcholine acyltransferase 1
254531 LPCAT4; lysophosphatidylcholine acyltransferase 4
9926 LPGAT1; lysophosphatidylglycerol acyltransferase 1
10162 LPCAT3; lysophosphatidylcholine acyltransferase 3
79143 MBOAT7; membrane bound O-acyltransferase domain containing 7
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K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]
K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K11993 ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-]
K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]
K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]
K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K10225 FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-]
K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]
K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K12419 FADS6; fatty acid desaturase 6 [EC:1.14.19.-]
K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]
K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16]
K23756 ACSM1; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-]
K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
K13513 LCLAT1; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]
K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]
K13515 LPCAT3; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]
K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]
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01008 Polyketide biosynthesis proteins
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01006 Prenyltransferases [BR:hsa01006]
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01007 Amino acid related enzymes [BR:hsa01007]
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00199 Cytochrome P450 [BR:hsa00199]
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00194 Photosynthesis proteins
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09182 Protein families: genetic information processing
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09183 Protein families: signaling and cellular processes
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)