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KO |
 09100 Metabolism
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 09101 Carbohydrate metabolism
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09102 Energy metabolism
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09103 Lipid metabolism
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09104 Nucleotide metabolism
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00230 Purine metabolism [PATH:hsa00230]
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 53343 NUDT9; nudix hydrolase 9
56985 ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
11164 NUDT5; nudix hydrolase 5
5236 PGM1; phosphoglucomutase 1
55276 PGM2; phosphoglucomutase 2
221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1 like 1
5634 PRPS2; phosphoribosyl pyrophosphate synthetase 2
5631 PRPS1; phosphoribosyl pyrophosphate synthetase 1
5471 PPAT; phosphoribosyl pyrophosphate amidotransferase
2618 GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
5198 PFAS; phosphoribosylformylglycinamidine synthase
10606 PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
158 ADSL; adenylosuccinate lyase
471 ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
353 APRT; adenine phosphoribosyltransferase
22978 NT5C2; 5'-nucleotidase, cytosolic II
84618 NT5C1A; 5'-nucleotidase, cytosolic IA
93034 NT5C1B; 5'-nucleotidase, cytosolic IB
30833 NT5C; 5', 3'-nucleotidase, cytosolic
56953 NT5M; 5',3'-nucleotidase, mitochondrial
100526794 NT5C1B-RDH14; NT5C1B-RDH14 readthrough
284958 NT5DC4; 5'-nucleotidase domain containing 4
4907 NT5E; 5'-nucleotidase ecto
4860 PNP; purine nucleoside phosphorylase
144811 LACC1; laccase domain containing 1
3251 HPRT1; hypoxanthine phosphoribosyltransferase 1
3614 IMPDH1; inosine monophosphate dehydrogenase 1
3615 IMPDH2; inosine monophosphate dehydrogenase 2
10201 NME6; NME/NM23 nucleoside diphosphate kinase 6
29922 NME7; NME/NM23 family member 7
4831 NME2; NME/NM23 nucleoside diphosphate kinase 2
4833 NME4; NME/NM23 nucleoside diphosphate kinase 4
4830 NME1; NME/NM23 nucleoside diphosphate kinase 1
4832 NME3; NME/NM23 nucleoside diphosphate kinase 3
654364 NME1-NME2; NME1-NME2 readthrough
221264 AK9; adenylate kinase 9
956 ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3
377841 ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8
953 ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1
124583 CANT1; calcium activated nucleotidase 1
9583 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4
957 ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
955 ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6
131870 NUDT16; nudix hydrolase 16
3704 ITPA; inosine triphosphatase
7498 XDH; xanthine dehydrogenase
318 NUDT2; nudix hydrolase 2
8833 GMPS; guanine monophosphate synthase
2766 GMPR; guanosine monophosphate reductase
51292 GMPR2; guanosine monophosphate reductase 2
9615 GDA; guanine deaminase
2987 GUK1; guanylate kinase 1
6240 RRM1; ribonucleotide reductase catalytic subunit M1
50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
6241 RRM2; ribonucleotide reductase regulatory subunit M2
51020 HDDC2; HD domain containing 2
1716 DGUOK; deoxyguanosine kinase
1633 DCK; deoxycytidine kinase
374659 HDDC3; HD domain containing 3
58497 PRUNE1; prune exopolyphosphatase 1
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
55811 ADCY10; adenylate cyclase 10
2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
2984 GUCY2C; guanylate cyclase 2C
3000 GUCY2D; guanylate cyclase 2D, retinal
2986 GUCY2F; guanylate cyclase 2F, retinal
4881 NPR1; natriuretic peptide receptor 1
4882 NPR2; natriuretic peptide receptor 2
5136 PDE1A; phosphodiesterase 1A
5153 PDE1B; phosphodiesterase 1B
5137 PDE1C; phosphodiesterase 1C
5138 PDE2A; phosphodiesterase 2A
5139 PDE3A; phosphodiesterase 3A
5140 PDE3B; phosphodiesterase 3B
8654 PDE5A; phosphodiesterase 5A
5145 PDE6A; phosphodiesterase 6A
5158 PDE6B; phosphodiesterase 6B
5146 PDE6C; phosphodiesterase 6C
5147 PDE6D; phosphodiesterase 6D
5148 PDE6G; phosphodiesterase 6G
5149 PDE6H; phosphodiesterase 6H
5152 PDE9A; phosphodiesterase 9A
10846 PDE10A; phosphodiesterase 10A
50940 PDE11A; phosphodiesterase 11A
122622 ADSS1; adenylosuccinate synthase 1
159 ADSS2; adenylosuccinate synthase 2
271 AMPD2; adenosine monophosphate deaminase 2
272 AMPD3; adenosine monophosphate deaminase 3
270 AMPD1; adenosine monophosphate deaminase 1
132 ADK; adenosine kinase
100 ADA; adenosine deaminase
51816 ADA2; adenosine deaminase 2
122481 AK7; adenylate kinase 7
205 AK4; adenylate kinase 4
26289 AK5; adenylate kinase 5
204 AK2; adenylate kinase 2
203 AK1; adenylate kinase 1
158067 AK8; adenylate kinase 8
102157402 AK6; adenylate kinase 6
50808 AK3; adenylate kinase 3
954 ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2
84284 NTPCR; nucleoside-triphosphatase, cancer-related
5167 ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1
5169 ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3
5141 PDE4A; phosphodiesterase 4A
5142 PDE4B; phosphodiesterase 4B
5143 PDE4C; phosphodiesterase 4C
5144 PDE4D; phosphodiesterase 4D
5150 PDE7A; phosphodiesterase 7A
27115 PDE7B; phosphodiesterase 7B
8622 PDE8B; phosphodiesterase 8B
5151 PDE8A; phosphodiesterase 8A
2272 FHIT; fragile histidine triad diadenosine triphosphatase
22875 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4
9060 PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2
9061 PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1
646625 URAD; ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
55821 ALLC; allantoicase
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K13988 NUDT9; ADP-ribose diphosphatase [EC:3.6.1.13]
K01517 ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
K13987 NUDT5; ADP-ribose diphosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 2.7.7.96]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K01587 PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K18533 AK9; adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K12304 CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
K12305 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K00364 guaC; GMP reductase [EC:1.7.1.7]
K00364 guaC; GMP reductase [EC:1.7.1.7]
K01487 guaD; guanine deaminase [EC:3.5.4.3]
K00942 gmk; guanylate kinase [EC:2.7.4.8]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K07023 YGK1; 5'-deoxynucleotidase [EC:3.1.3.89]
K00904 DGUOK; deoxyguanosine kinase [EC:2.7.1.113]
K00893 DCK; deoxycitidine/deoxyadenosine/deoxyguanosine kinase [EC:2.7.1.74 2.7.1.76 2.7.1.113]
K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
K01514 PRUNE; exopolyphosphatase [EC:3.6.1.11]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13762 PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
K08718 PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]
K13756 PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]
K13757 PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35]
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
K13759 PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13760 PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13761 PDE9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K00856 ADK; adenosine kinase [EC:2.7.1.20]
K01488 add; adenosine deaminase [EC:3.5.4.4]
K19572 CECR1; adenosine deaminase CECR1 [EC:3.5.4.4]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K18532 AK6; adenylate kinase [EC:2.7.4.3]
K00944 AK3; nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10]
K01509 ENTPD2; adenosinetriphosphatase [EC:3.6.1.-]
K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K18424 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13485 PRHOXNB; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
K01477 alc; allantoicase [EC:3.5.3.4]
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00240 Pyrimidine metabolism [PATH:hsa00240]
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system
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04010 MAPK signaling pathway [PATH:hsa04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:hsa04012]
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04014 Ras signaling pathway [PATH:hsa04014]
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04015 Rap1 signaling pathway [PATH:hsa04015]
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04310 Wnt signaling pathway [PATH:hsa04310]
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04330 Notch signaling pathway [PATH:hsa04330]
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04340 Hedgehog signaling pathway [PATH:hsa04340]
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:hsa04350]
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04390 Hippo signaling pathway [PATH:hsa04390]
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04391 Hippo signaling pathway - fly
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04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
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04370 VEGF signaling pathway [PATH:hsa04370]
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04371 Apelin signaling pathway [PATH:hsa04371]
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04630 JAK-STAT signaling pathway [PATH:hsa04630]
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04064 NF-kappa B signaling pathway [PATH:hsa04064]
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04668 TNF signaling pathway [PATH:hsa04668]
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04066 HIF-1 signaling pathway [PATH:hsa04066]
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04068 FoxO signaling pathway [PATH:hsa04068]
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04020 Calcium signaling pathway [PATH:hsa04020]
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04070 Phosphatidylinositol signaling system [PATH:hsa04070]
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04072 Phospholipase D signaling pathway [PATH:hsa04072]
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04071 Sphingolipid signaling pathway [PATH:hsa04071]
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04024 cAMP signaling pathway [PATH:hsa04024]
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04022 cGMP-PKG signaling pathway [PATH:hsa04022]
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185 AGTR1; angiotensin II receptor type 1
1909 EDNRA; endothelin receptor type A
1910 EDNRB; endothelin receptor type B
148 ADRA1A; adrenoceptor alpha 1A
147 ADRA1B; adrenoceptor alpha 1B
146 ADRA1D; adrenoceptor alpha 1D
150 ADRA2A; adrenoceptor alpha 2A
151 ADRA2B; adrenoceptor alpha 2B
152 ADRA2C; adrenoceptor alpha 2C
2776 GNAQ; G protein subunit alpha q
2767 GNA11; G protein subunit alpha 11
2768 GNA12; G protein subunit alpha 12
10672 GNA13; G protein subunit alpha 13
7225 TRPC6; transient receptor potential cation channel subfamily C member 6
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
4205 MEF2A; myocyte enhancer factor 2A
4207 BORCS8-MEF2B; BORCS8-MEF2B readthrough
100271849 MEF2B; myocyte enhancer factor 2B
4208 MEF2C; myocyte enhancer factor 2C
4209 MEF2D; myocyte enhancer factor 2D
4772 NFATC1; nuclear factor of activated T cells 1
4773 NFATC2; nuclear factor of activated T cells 2
4775 NFATC3; nuclear factor of activated T cells 3
4776 NFATC4; nuclear factor of activated T cells 4
6722 SRF; serum response factor
2626 GATA4; GATA binding protein 4
4625 MYH7; myosin heavy chain 7
4624 MYH6; myosin heavy chain 6
4879 NPPB; natriuretic peptide B
4878 NPPA; natriuretic peptide A
4881 NPR1; natriuretic peptide receptor 1
4880 NPPC; natriuretic peptide C
4882 NPR2; natriuretic peptide receptor 2
5592 PRKG1; protein kinase cGMP-dependent 1
5593 PRKG2; protein kinase cGMP-dependent 2
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
3778 KCNMA1; potassium calcium-activated channel subfamily M alpha 1
157855 KCNU1; potassium calcium-activated channel subfamily U member 1
3779 KCNMB1; potassium calcium-activated channel subfamily M regulatory beta subunit 1
10242 KCNMB2; potassium calcium-activated channel subfamily M regulatory beta subunit 2
27094 KCNMB3; potassium calcium-activated channel subfamily M regulatory beta subunit 3
27345 KCNMB4; potassium calcium-activated channel subfamily M regulatory beta subunit 4
6546 SLC8A1; solute carrier family 8 member A1
6543 SLC8A2; solute carrier family 8 member A2
6547 SLC8A3; solute carrier family 8 member A3
476 ATP1A1; ATPase Na+/K+ transporting subunit alpha 1
477 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2
478 ATP1A3; ATPase Na+/K+ transporting subunit alpha 3
480 ATP1A4; ATPase Na+/K+ transporting subunit alpha 4
23439 ATP1B4; ATPase Na+/K+ transporting family member beta 4
481 ATP1B1; ATPase Na+/K+ transporting subunit beta 1
482 ATP1B2; ATPase Na+/K+ transporting subunit beta 2
483 ATP1B3; ATPase Na+/K+ transporting subunit beta 3
486 FXYD2; FXYD domain containing ion transport regulator 2
490 ATP2B1; ATPase plasma membrane Ca2+ transporting 1
492 ATP2B3; ATPase plasma membrane Ca2+ transporting 3
493 ATP2B4; ATPase plasma membrane Ca2+ transporting 4
491 ATP2B2; ATPase plasma membrane Ca2+ transporting 2
5997 RGS2; regulator of G protein signaling 2
2969 GTF2I; general transcription factor IIi
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
10335 IRAG1; inositol 1,4,5-triphosphate receptor associated 1
5350 PLN; phospholamban
487 ATP2A1; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
489 ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
488 ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
387 RHOA; ras homolog family member A
6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
4638 MYLK; myosin light chain kinase
85366 MYLK2; myosin light chain kinase 2
91807 MYLK3; myosin light chain kinase 3
340156 MYLK4; myosin light chain kinase family member 4
10398 MYL9; myosin light chain 9
1259 CNGA1; cyclic nucleotide gated channel subunit alpha 1
1258 CNGB1; cyclic nucleotide gated channel subunit beta 1
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
109 ADCY3; adenylate cyclase 3
196883 ADCY4; adenylate cyclase 4
111 ADCY5; adenylate cyclase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
5138 PDE2A; phosphodiesterase 2A
5139 PDE3A; phosphodiesterase 3A
5140 PDE3B; phosphodiesterase 3B
8654 PDE5A; phosphodiesterase 5A
2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
3827 KNG1; kininogen 1
624 BDKRB2; bradykinin receptor B2
4985 OPRD1; opioid receptor delta 1
134 ADORA1; adenosine A1 receptor
140 ADORA3; adenosine A3 receptor
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
4846 NOS3; nitric oxide synthase 3
153 ADRB1; adrenoceptor beta 1
154 ADRB2; adrenoceptor beta 2
155 ADRB3; adrenoceptor beta 3
5581 PRKCE; protein kinase C epsilon
3764 KCNJ8; potassium inwardly rectifying channel subfamily J member 8
7416 VDAC1; voltage dependent anion channel 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
291 SLC25A4; solute carrier family 25 member 4
292 SLC25A5; solute carrier family 25 member 5
293 SLC25A6; solute carrier family 25 member 6
83447 SLC25A31; solute carrier family 25 member 31
10105 PPIF; peptidylprolyl isomerase F
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
1388 ATF6B; activating transcription factor 6 beta
572 BAD; BCL2 associated agonist of cell death
7408 VASP; vasodilator stimulated phosphoprotein
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
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K04166 AGTR1; angiotensin II receptor type 1
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K04138 ADRA2A; adrenergic receptor alpha-2A
K04139 ADRA2B; adrenergic receptor alpha-2B
K04140 ADRA2C; adrenergic receptor alpha-2C
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04969 TRPC6; transient receptor potential cation channel subfamily C member 6
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K09262 MEF2D; MADS-box transcription enhancer factor 2D
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K04378 SRF; serum response factor
K09183 GATA4; GATA-binding protein 4
K17751 MYH6_7; myosin heavy chain 6/7
K17751 MYH6_7; myosin heavy chain 6/7
K12335 NPPB; natriuretic peptide B
K12334 NPPA; natriuretic peptide A
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12336 NPPC; natriuretic peptide C
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K05274 KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
K04937 KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
K04938 KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
K04939 KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
K04941 KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K05849 SLC8A; solute carrier family 8 (sodium/calcium exchanger)
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K18154 RGS2; regulator of G-protein signaling 2
K03121 TFII-I; transcription initiation factor TFII-I
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K12337 MRVI1; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12755 MYL9; myosin regulatory light chain 9
K04948 CNGA1; cyclic nucleotide gated channel alpha 1
K04952 CNGB1; cyclic nucleotide gated channel beta 1
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13762 PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K03898 KNG; kininogen
K03916 BDKRB2; bradykinin receptor B2
K04213 OPRD1; delta-type opioid receptor
K04265 ADORA1; adenosine receptor A1
K04268 ADORA3; adenosine receptor A3
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04143 ADRB3; adrenergic receptor beta-3
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K05001 KCNJ8; potassium inwardly-rectifying channel subfamily J member 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K02158 BAD; Bcl-2-antagonist of cell death
K06274 VASP; vasodilator-stimulated phosphoprotein
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
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04151 PI3K-Akt signaling pathway [PATH:hsa04151]
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04152 AMPK signaling pathway [PATH:hsa04152]
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04150 mTOR signaling pathway [PATH:hsa04150]
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)