Peptidases and Inhibitors - Homo sapiens (human)

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 Aspartic peptidases
 Cysteine peptidases
 Glutamic peptidases
 Metallo peptidases
 Mixed peptidases
 Serine peptidases
   Family S1: chymotrypsin family
     440387 CTRB2; chymotrypsinogen B2
     1504 CTRB1; chymotrypsinogen B1
     23430 TPSD1; tryptase delta 1
     7177 TPSAB1; tryptase alpha/beta 1
     64499 TPSB2; tryptase beta 2
     10699 CORIN; corin, serine peptidase
     341350 OVCH1; ovochymase 1
     341277 OVCH2; ovochymase 2
     25823 TPSG1; tryptase gamma 1
     3026 HABP2; hyaluronan binding protein 2
     5646 PRSS3; serine protease 3
     5645 PRSS2; serine protease 2
     5644 PRSS1; serine protease 1
     5651 TMPRSS15; transmembrane serine protease 15
     5652 PRSS8; serine protease 8
     8492 PRSS12; serine protease 12
     10942 PRSS21; serine protease 21
     360226 PRSS41; serine protease 41
     64063 PRSS22; serine protease 22
     83886 PRSS27; serine protease 27
     260429 PRSS33; serine protease 33
     146547 PRSS36; serine protease 36
     646960 PRSS56; serine protease 56
     400668 PRSS57; serine protease 57
     136541 PRSS58; serine protease 58
     1991 ELANE; elastase, neutrophil expressed
     1511 CTSG; cathepsin G
     5657 PRTN3; proteinase 3
     3001 GZMA; granzyme A
     3002 GZMB; granzyme B
     2999 GZMH; granzyme H
     3003 GZMK; granzyme K
     3004 GZMM; granzyme M
     1215 CMA1; chymase 1
     1990 CELA1; chymotrypsin like elastase 1
     63036 CELA2A; chymotrypsin like elastase 2A
     51032 CELA2B; chymotrypsin like elastase 2B
     10136 CELA3A; chymotrypsin like elastase 3A
     23436 CELA3B; chymotrypsin like elastase 3B
     11330 CTRC; chymotrypsin C
     3817 KLK2; kallikrein related peptidase 2
     3816 KLK1; kallikrein 1
     3818 KLKB1; kallikrein B1
     354 KLK3; kallikrein related peptidase 3
     9622 KLK4; kallikrein related peptidase 4
     25818 KLK5; kallikrein related peptidase 5
     5653 KLK6; kallikrein related peptidase 6
     5650 KLK7; kallikrein related peptidase 7
     11202 KLK8; kallikrein related peptidase 8
     284366 KLK9; kallikrein related peptidase 9
     5655 KLK10; kallikrein related peptidase 10
     11012 KLK11; kallikrein related peptidase 11
     43849 KLK12; kallikrein related peptidase 12
     26085 KLK13; kallikrein related peptidase 13
     43847 KLK14; kallikrein related peptidase 14
     55554 KLK15; kallikrein related peptidase 15
     5648 MASP1; mannan binding lectin serine peptidase 1
     10747 MASP2; mannan binding lectin serine peptidase 2
     715 C1R; complement C1r
     716 C1S; complement C1s
     717 C2; complement C2
     629 CFB; complement factor B
     1675 CFD; complement factor D
     3426 CFI; complement factor I
     2147 F2; coagulation factor II, thrombin
     2155 F7; coagulation factor VII
     2158 F9; coagulation factor IX
     2159 F10; coagulation factor X
     2160 F11; coagulation factor XI
     2161 F12; coagulation factor XII
     5624 PROC; protein C, inactivator of coagulation factors Va and VIIIa
     49 ACR; acrosin
     3249 HPN; hepsin
     3083 HGFAC; HGF activator
     5327 PLAT; plasminogen activator, tissue type
     5328 PLAU; plasminogen activator, urokinase
     5340 PLG; plasminogen
     7113 TMPRSS2; transmembrane serine protease 2
     64699 TMPRSS3; transmembrane serine protease 3
     56649 TMPRSS4; transmembrane serine protease 4
     80975 TMPRSS5; transmembrane serine protease 5
     164656 TMPRSS6; transmembrane serine protease 6
     344805 TMPRSS7; transmembrane serine protease 7
     360200 TMPRSS9; transmembrane serine protease 9
     339967 TMPRSS11A; transmembrane serine protease 11A
     132724 TMPRSS11B; transmembrane serine protease 11B
     9407 TMPRSS11D; transmembrane serine protease 11D
     28983 TMPRSS11E; transmembrane serine protease 11E
     389208 TMPRSS11F; transmembrane serine protease 11F
     84000 TMPRSS13; transmembrane serine protease 13
     1506 CTRL; chymotrypsin like
     6768 ST14; ST14 transmembrane serine protease matriptase
     3240 HP; haptoglobin
     4485 MST1; macrophage stimulating 1
     4018 LPA; lipoprotein(a)
     5654 HTRA1; HtrA serine peptidase 1
     27429 HTRA2; HtrA serine peptidase 2
     94031 HTRA3; HtrA serine peptidase 3
     203100 HTRA4; HtrA serine peptidase 4
     219743 TYSND1; trypsin domain containing 1
     11098 PRSS23; serine protease 23
K01310 CTRB; chymotrypsin [EC:] 
K01310 CTRB; chymotrypsin [EC:] 
K01340 E3.4.21.59; tryptase [EC:] 
K01340 E3.4.21.59; tryptase [EC:] 
K01340 E3.4.21.59; tryptase [EC:] 
K09614 CORIN; atrial natriuretic peptide-converting enzyme [EC:3.4.21.-] 
K01362 OVCH; ovochymase [EC:3.4.21.-] 
K01362 OVCH; ovochymase [EC:3.4.21.-] 
K09615 TPSG1; tryptase gamma 1 [EC:3.4.21.-] 
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-] 
K01312 PRSS1_2_3; trypsin [EC:] 
K01312 PRSS1_2_3; trypsin [EC:] 
K01312 PRSS1_2_3; trypsin [EC:] 
K01316 TMPRSS15; enterokinase [EC:] 
K08664 PRSS8; prostasin [EC:3.4.21.-] 
K09624 PRSS12; neurotrypsin [EC:3.4.21.-] 
K09625 PRSS21; testisin [EC:3.4.21.-] 
K09625 PRSS21; testisin [EC:3.4.21.-] 
K09626 PRSS22; brain-specific serine protease 4 [EC:3.4.21.-] 
K09628 PRSS27; serine protease 27 [EC:3.4.21.-] 
K09629 PRSS33; serine protease 33 [EC:3.4.21.-] 
K09630 PRSS36; polyserase 2 [EC:3.4.21.-] 
K23440 PRSS56; serine protease 56 [EC:3.4.21.-] 
K23011 PRSS57; serine protease 57 [EC:3.4.21.-] 
K22367 PRSS58; serine protease 58 [EC:3.4.21.-] 
K01327 ELANE; leukocyte elastase [EC:] 
K01319 CTSG; cathepsin G [EC:] 
K01350 PRTN3; myeloblastin [EC:] 
K01352 GZMA; granzyme A [EC:] 
K01353 GZMB; granzyme B [EC:] 
K09616 GZMH; granzyme H (cathepsin G-like 2) [EC:3.4.21.-] 
K08663 GZMK; granzyme K [EC:3.4.21.-] 
K08649 GZMM; granzyme M [EC:3.4.21.-] 
K01329 CMA1; chymase [EC:] 
K01326 CELA1; pancreatic elastase I [EC:] 
K01346 CELA2; pancreatic elastase II [EC:] 
K01346 CELA2; pancreatic elastase II [EC:] 
K01345 CELA3; pancreatic endopeptidase E [EC:] 
K01345 CELA3; pancreatic endopeptidase E [EC:] 
K01311 CTRC; chymotrypsin C [EC:] 
K01325 KLK1_2; tissue kallikrein [EC:] 
K01325 KLK1_2; tissue kallikrein [EC:] 
K01324 KLKB1; plasma kallikrein [EC:] 
K01351 KLK3; semenogelase [EC:] 
K08666 KLK4; kallikrein 4 [EC:3.4.21.-] 
K09617 KLK5; kallikrein 5 [EC:3.4.21.-] 
K08667 KLK6; kallikrein 6 [EC:3.4.21.-] 
K08668 KLK7; kallikrein 7 [EC:] 
K08650 KLK8; kallikrein 8 [EC:] 
K09618 KLK9; kallikrein 9 [EC:3.4.21.-] 
K09619 KLK10; kallikrein 10 [EC:3.4.21.-] 
K09620 KLK11; kallikrein 11 [EC:3.4.21.-] 
K09621 KLK12; kallikrein 12 [EC:3.4.21.-] 
K09463 KLK13; kallikrein 13 [EC:] 
K09622 KLK14; kallikrein 14 [EC:3.4.21.-] 
K09623 KLK15; kallikrein 15 [EC:3.4.21.-] 
K03992 MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-] 
K03993 MASP2; mannan-binding lectin serine protease 2 [EC:] 
K01330 C1R; complement component 1, r subcomponent [EC:] 
K01331 C1S; complement component 1, s subcomponent [EC:] 
K01332 C2; complement component 2 [EC:] 
K01335 CFB; complement factor B [EC:] 
K01334 CFD; complement factor D [EC:] 
K01333 CFI; complement factor I [EC:] 
K01313 F2; coagulation factor II (thrombin) [EC:] 
K01320 F7; coagulation factor VII [EC:] 
K01321 F9; coagulation factor IX (Christmas factor) [EC:] 
K01314 F10; coagulation factor X [EC:] 
K01323 F11; coagulation factor XI [EC:] 
K01328 F12; coagulation factor XII (Hageman factor) [EC:] 
K01344 PROC; protein C (activated) [EC:] 
K01317 ACR; acrosin [EC:] 
K08665 HPN; hepsin [EC:] 
K09631 HGFAC; hepatocyte growth factor activator [EC:3.4.21.-] 
K01343 PLAT; tissue plasminogen activator [EC:] 
K01348 PLAU; urokinase plasminogen activator [EC:] 
K01315 PLG; plasminogen [EC:] 
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.-] 
K09634 TMPRSS3; transmembrane protease serine 3 [EC:3.4.21.-] 
K09635 TMPRSS4; transmembrane protease serine 4 [EC:3.4.21.-] 
K09636 TMPRSS5; transmembrane protease serine 5 [EC:3.4.21.-] 
K09637 TMPRSS6; transmembrane protease serine 6 [EC:3.4.21.-] 
K09638 TMPRSS7; transmembrane protease serine 7 [EC:3.4.21.-] 
K09640 TMPRSS9; transmembrane protease serine 9 [EC:3.4.21.-] 
K09750 TMPRSS11A; transmembrane protease serine 11A [EC:3.4.21.-] 
K09751 TMPRSS11B; transmembrane protease serine 11B [EC:3.4.21.-] 
K09641 TMPRSS11D; transmembrane protease serine 11D [EC:3.4.21.-] 
K09642 TMPRSS11E; transmembrane protease serine 11E [EC:3.4.21.-] 
K09752 TMPRSS11F; transmembrane protease serine 11F [EC:3.4.21.-] 
K09643 TMPRSS13; transmembrane protease serine 13 
K09632 CTRL; chymotrypsin-like protease [EC:3.4.21.-] 
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:] 
K16142 HP; haptoglobin 
K23441 MST1; hepatocyte growth factor-like protein 
K09644 LPA; apolipoprotein(a) [EC:3.4.21.-] 
K08784 HTRA1; HtrA serine peptidase 1 [EC:3.4.21.-] 
K08669 HTRA2; HtrA serine peptidase 2 [EC:] 
K08785 HTRA3; HtrA serine peptidase 3 [EC:3.4.21.-] 
K08786 HTRA4; HtrA serine peptidase 4 [EC:3.4.21.-] 
K23012 TYSND1; peroxisomal leader peptide-processing protease [EC:3.4.21.-] 
K09627 PRSS23; serine protease 23 [EC:3.4.21.-] 
   Family S6
   Family S8: subtilisin family
   Family S9: prolyl oligopeptidase family
   Family S10
   Family S11: D-Ala-D-Ala carboxypeptidase A family
   Family S12: D-Ala-D-Ala carboxypeptidase B family
   Family S13: D-Ala-D-Ala peptidase C family
   Family S14: ClpP endopeptidase family
   Family S15
   Family S16: lon protease family
   Family S24: LexA family
   Family S26: signal peptidase I family
   Family S28
   Family S33
   Family S41: C-terminal processing peptidase family
   Family S45
   Family S49: protease IV family
   Family S51
   Family S53
   Family S54: Rhomboid family
   Family S55: SpoIVB peptidase family
   Family S66
 Threonine peptidases
 Peptidases of unknown catalytic type
 Peptidase inhibitors

Last updated: July 15, 2020
Classification taken and modified from MEROPS