DNA Repair and Recombination Proteins - Homo sapiens (human)

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     KO 
 Eukaryotic type

   SSBR (single strand breaks repair)

     Direct repair

     BER (base exicision repair)

       DNA glycosylases

       AP endonucleases

       Long Patch-BER factors

       Short Patch-BER factors

       Other BER factors

         55775 TDP1; tyrosyl-DNA phosphodiesterase 1
         54840 APTX; aprataxin
         200558 APLF; aprataxin and PNKP like factor
         11284 PNKP; polynucleotide kinase 3'-phosphatase
         3146 HMGB1; high mobility group box 1
         27343 POLL; DNA polymerase lambda
         142 PARP1; poly(ADP-ribose) polymerase 1
         10038 PARP2; poly(ADP-ribose) polymerase 2
         10039 PARP3; poly(ADP-ribose) polymerase family member 3
         143 PARP4; poly(ADP-ribose) polymerase family member 4

K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] 
K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] 
K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
K10802 HMGB1; high mobility group protein B1 
K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] 
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 

     NER (nucleotide excision repair)

     MMR (mismatch excision repair)

   DSBR (double strand breaks repair)

   TLS (translesion DNA synthesis) factors

   Check point factors

   Other factors with a suspected DNA repair function

 





 Prokaryotic type













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Last updated: March 29, 2024