DNA Repair and Recombination Proteins - Homo sapiens (human)

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     KO
 Eukaryotic type
   SSBR (single strand breaks repair)
   DSBR (double strand breaks repair)
     HR (homologous recombination)
       MRN(MRX) complex
       BRCA1-A complex
         672 BRCA1; BRCA1 DNA repair associated
         84142 ABRAXAS1; abraxas 1, BRCA1 A complex subunit
         51720 UIMC1; ubiquitin interaction motif containing 1
         29086 BABAM1; BRISC and BRCA1 A complex member 1
         9577 BABAM2; BRISC and BRCA1 A complex member 2
         79184 BRCC3; BRCA1/BRCA2-containing complex subunit 3
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
K20774 FAM175A; BRCA1-A complex subunit Abraxas 
K20775 UIMC1; BRCA1-A complex subunit RAP80 
K20776 BABAM; BRISC and BRCA1-A complex member 1 
K12173 BRE; BRCA1-A complex subunit BRE 
K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] 
       BRCA1-B complex
         672 BRCA1; BRCA1 DNA repair associated
         83990 BRIP1; BRCA1 interacting protein C-terminal helicase 1
         11073 TOPBP1; DNA topoisomerase II binding protein 1
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
K15362 BRIP1; fanconi anemia group J protein [EC:3.6.4.12] 
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 
       BRCA1-C complex
         672 BRCA1; BRCA1 DNA repair associated
         5932 RBBP8; RB binding protein 8, endonuclease
         4361 MRE11; MRE11 homolog, double strand break repair nuclease
         10111 RAD50; RAD50 double strand break repair protein
         4683 NBN; nibrin
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-] 
K10865 MRE11; double-strand break repair protein MRE11 
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
K10867 NBN; nibrin 
       BRCA complex
         672 BRCA1; BRCA1 DNA repair associated
         675 BRCA2; BRCA2 DNA repair associated
         79728 PALB2; partner and localizer of BRCA2
         5888 RAD51; RAD51 recombinase
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
K08775 BRCA2; breast cancer 2 susceptibility protein 
K10897 PALB2; partner and localizer of BRCA2 
K04482 RAD51; DNA repair protein RAD51 
       RecA family proteins
       Rad52 family proteins
       Rad54 family proteins
       RecQ family DNA helicases
       Bloom's syndrome complex (BTR)
       RPA (replication factor A)
       Protein phosphatase 4
       AP-5 complex
       SMC5-SMC6 complex
       Other HR factors
     NHEJ (non-homologous end-joining)
     FA (Fanconi anemia) pathway
       FA core complex
       FA core complex binding factors
       Bloom's syndrome complex (BTR)
       FANCD2-I complex
       Downstream FA components
         672 BRCA1; BRCA1 DNA repair associated
         675 BRCA2; BRCA2 DNA repair associated
         83990 BRIP1; BRCA1 interacting protein C-terminal helicase 1
         79728 PALB2; partner and localizer of BRCA2
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] 
K08775 BRCA2; breast cancer 2 susceptibility protein 
K15362 BRIP1; fanconi anemia group J protein [EC:3.6.4.12] 
K10897 PALB2; partner and localizer of BRCA2 
       Other FA pathway factors
     Other DSBR factors
   TLS (translesion DNA synthesis) factors
   Check point factors
   Other factors with a suspected DNA repair function
 
 Prokaryotic type

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Last updated: May 8, 2020