Ubiquitin System - Homo sapiens (human)

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     KO 
 Ubiquitins and ubiquitin-like proteins

 





 Ubiquitin-activating enzymes (E1)





 







 Ubiquitin-conjugating enzymes (E2)





 







 Ubiquitin ligases (E3)





   HECT type E3





   U-box type E3





   Single Ring-finger type E3





   Atypical E3





   UBL E3 ligases





   Multi subunit Ring-finger type E3





     SCF complex





       Ring finger protein





       Cullin





       Adaptor protein





       Target recognizing subunit (F-box)





         8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
         23291 FBXW11; F-box and WD repeat domain containing 11
         26190 FBXW2; F-box and WD repeat domain containing 2
         6468 FBXW4; F-box and WD repeat domain containing 4
         54461 FBXW5; F-box and WD repeat domain containing 5
         55294 FBXW7; F-box and WD repeat domain containing 7
         26259 FBXW8; F-box and WD repeat domain containing 8
         84261 FBXW9; F-box and WD repeat domain containing 9
         10517 FBXW10; F-box and WD repeat domain containing 10
         374286 FBXW10B; F-box and WD repeat domain containing 10B
         285231 FBXW12; F-box and WD repeat domain containing 12
         6502 SKP2; S-phase kinase associated protein 2
         25827 FBXL2; F-box and leucine rich repeat protein 2
         84961 FBXL20; F-box and leucine rich repeat protein 20
         26224 FBXL3; F-box and leucine rich repeat protein 3
         26235 FBXL4; F-box and leucine rich repeat protein 4
         26234 FBXL5; F-box and leucine rich repeat protein 5
         26233 FBXL6; F-box and leucine rich repeat protein 6
         23194 FBXL7; F-box and leucine rich repeat protein 7
         55336 FBXL8; F-box and leucine rich repeat protein 8
         84678 KDM2B; lysine demethylase 2B
         22992 KDM2A; lysine demethylase 2A
         54850 FBXL12; F-box and leucine rich repeat protein 12
         222235 FBXL13; F-box and leucine rich repeat protein 13
         144699 FBXL14; F-box and leucine rich repeat protein 14
         79176 FBXL15; F-box and leucine rich repeat protein 15
         146330 FBXL16; F-box and leucine rich repeat protein 16
         64839 FBXL17; F-box and leucine rich repeat protein 17
         80028 FBXL18; F-box and leucine rich repeat protein 18
         54620 FBXL19; F-box and leucine rich repeat protein 19
         283807 FBXL22; F-box and leucine rich repeat protein 22
         899 CCNF; cyclin F
         26232 FBXO2; F-box protein 2
         26273 FBXO3; F-box protein 3
         26272 FBXO4; F-box protein 4
         26271 FBXO5; F-box protein 5
         26270 FBXO6; F-box protein 6
         25793 FBXO7; F-box protein 7
         26269 FBXO8; F-box protein 8
         26268 FBXO9; F-box protein 9
         26267 FBXO10; F-box protein 10
         80204 FBXO11; F-box protein 11
         201456 FBXO15; F-box protein 15
         157574 FBXO16; F-box protein 16
         115290 FBXO17; F-box protein 17
         84893 FBH1; F-box DNA helicase 1
         4008 LMO7; LIM domain 7
         23014 FBXO21; F-box protein 21
         26263 FBXO22; F-box protein 22
         26262 TSPAN17; tetraspanin 17
         26261 FBXO24; F-box protein 24
         26260 FBXO25; F-box protein 25
         114907 FBXO32; F-box protein 32
         126433 FBXO27; F-box protein 27
         23219 FBXO28; F-box protein 28
         84085 FBXO30; F-box protein 30
         79791 FBXO31; F-box protein 31
         254170 FBXO33; F-box protein 33
         55030 FBXO34; F-box protein 34
         130888 FBXO36; F-box protein 36
         81545 FBXO38; F-box protein 38
         162517 FBXO39; F-box protein 39
         51725 FBXO40; F-box protein 40
         150726 FBXO41; F-box protein 41
         54455 FBXO42; F-box protein 42
         286151 FBXO43; F-box protein 43
         93611 FBXO44; F-box protein 44
         200933 FBXO45; F-box protein 45
         23403 FBXO46; F-box protein 46
         494188 FBXO47; F-box protein 47
         554251 FBXO48; F-box protein 48



K03362 FBXW1_11; F-box and WD-40 domain protein 1/11 
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11 
K10261 FBXW2; F-box and WD-40 domain protein 2 
K10262 FBXW4; F-box and WD-40 domain protein 4 
K10263 FBXW5; F-box and WD-40 domain protein 5 
K10260 FBXW7; F-box and WD-40 domain protein 7 
K10264 FBXW8; F-box and WD-40 domain protein 8 
K10265 FBXW9; F-box and WD-40 domain protein 9 
K10266 FBXW10; F-box and WD-40 domain protein 10 
K10266 FBXW10; F-box and WD-40 domain protein 10 
K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19 
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2) 
K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20 
K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20 
K10269 FBXL3; F-box and leucine-rich repeat protein 3 
K10270 FBXL4; F-box and leucine-rich repeat protein 4 
K10271 FBXL5; F-box and leucine-rich repeat protein 5 
K10272 FBXL6; F-box and leucine-rich repeat protein 6 
K10273 FBXL7; F-box and leucine-rich repeat protein 7 
K10274 FBXL8; F-box and leucine-rich repeat protein 8 
K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] 
K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] 
K10278 FBXL12; F-box and leucine-rich repeat protein 12 
K10279 FBXL13; dynein regulatory complex subunit 6 
K10280 FBXL14; F-box and leucine-rich repeat protein 14 
K10281 FBXL15; F-box and leucine-rich repeat protein 15 
K10282 FBXL16; F-box and leucine-rich repeat protein 16 
K10283 FBXL17; F-box and leucine-rich repeat protein 17 
K10284 FBXL18; F-box and leucine-rich repeat protein 18 
K10285 FBXL19; F-box and leucine-rich repeat protein 19 
K10288 FBXL22; F-box and leucine-rich repeat protein 22 
K10289 CCNF; F-box protein 1 (cyclin F) 
K10099 FBXO2; F-box protein 2 
K10290 FBXO3; F-box protein 3 
K10291 FBXO4; F-box protein 4 
K10292 FBXO5; F-box protein 5 
K10100 FBXO6; F-box protein 6 
K10293 FBXO7; F-box protein 7 
K10294 FBXO8; F-box protein 8 
K10295 FBXO9; F-box protein 9 
K10296 FBXO10; F-box protein 10 
K10297 FBXO11; F-box protein 11 
K10298 FBXO15; F-box protein 15 
K10299 FBXO16; F-box protein 16 
K10101 FBXO17; F-box protein 17 
K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4] 
K06084 LMO7; F-box protein 20 
K10301 FBXO21; F-box protein 21 
K10302 FBXO22; F-box protein 22 
K10303 FBXO23; F-box protein 23 
K10304 FBXO24; F-box protein 24 
K10305 FBXO25_32; F-box protein 25/32 
K10305 FBXO25_32; F-box protein 25/32 
K10102 FBXO27; F-box protein 27 
K10306 FBXO28; F-box protein 28 
K10307 FBXO30; F-box protein 30 
K10308 FBXO31; F-box protein 31 
K10310 FBXO33; F-box protein 33 
K10311 FBXO34; F-box protein 34 
K10312 FBXO36; F-box protein 36 
K10313 FBXO38; F-box protein 38 
K10314 FBXO39; F-box protein 39 
K10315 FBXO40; F-box protein 40 
K10316 FBXO41; F-box protein 41 
K10317 FBXO42; F-box protein 42 
K10318 FBXO43; F-box protein 43 
K10103 FBXO44; F-box protein 44 
K10319 FBXO45; F-box protein 45 
K10320 FBXO46; F-box protein 46 
K10321 FBXO47; F-box protein 47 
K27313 FBXO48; F-box protein 48 





     Cul2 complex





     Cul3 complex





     Cul4 complex





     Cul5 complex





     Cul7 complex





     Cul8 complex





     Cul9 complex





     APC/C





     BRCC complex





     KPC complex





     LUBAC complex





     CTLH complex





     ERAD complex





     LMBR1L-GP78-UBAC2 complex





     SLX5-SLX8 complex





     Multi subunit type E3 associated proteins





 







 Deubiquitinating enzyme (DUB)













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Last updated: April 5, 2024