Ubiquitin System - Homo sapiens (human)

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     KO
 Ubiquitins and ubiquitin-like proteins
 
 Ubiquitin-activating enzymes (E1)
 
 Ubiquitin-conjugating enzymes (E2)
 
 Ubiquitin ligases (E3)
 
 Deubiquitinating enzyme (DUB)
   Ubiquitin-specific proteases (UBPs)
     UCH
     UBP/USP
     OTU
       55611 OTUB1; OTU deubiquitinase, ubiquitin aldehyde binding 1
       78990 OTUB2; OTU deubiquitinase, ubiquitin aldehyde binding 2
       23252 OTUD3; OTU deubiquitinase 3
       55593 OTUD5; OTU deubiquitinase 5
       139562 OTUD6A; OTU deubiquitinase 6A
       51633 OTUD6B; OTU deubiquitinase 6B
       161725 OTUD7A; OTU deubiquitinase 7A
       56957 OTUD7B; OTU deubiquitinase 7B
       90268 OTULIN; OTU deubiquitinase with linear linkage specificity
       7128 TNFAIP3; TNF alpha induced protein 3
       80124 VCPIP1; valosin containing protein interacting protein 1
       54764 ZRANB1; zinc finger RANBP2-type containing 1
K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12] 
K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12] 
K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12] 
K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12] 
K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12] 
K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12] 
K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12] 
K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12] 
K18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12] 
K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12] 
K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12] 
K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12] 
     MJD
     MINDY
     JAMM
     PPPDE
     ZUFSP
     BRISC complex
   UBL-specific proteases (ULPs)

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Last updated: February 21, 2024