Ubiquitin System - Homo sapiens (human)

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     KO
 Ubiquitins and ubiquitin-like proteins
 
 Ubiquitin-activating enzymes (E1)
 
 Ubiquitin-conjugating enzymes (E2)
 
 Ubiquitin ligases (E3)
   HECT type E3
     7337 UBE3A; ubiquitin protein ligase E3A
K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26] 
     89910 UBE3B; ubiquitin protein ligase E3B
K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26] 
     9690 UBE3C; ubiquitin protein ligase E3C
K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26] 
     90025 UBE3D; ubiquitin protein ligase E3D
K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26] 
     57154 SMURF1; SMAD specific E3 ubiquitin protein ligase 1
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26] 
     64750 SMURF2; SMAD specific E3 ubiquitin protein ligase 2
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26] 
     83737 ITCH; itchy E3 ubiquitin protein ligase
K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26] 
     11059 WWP1; WW domain containing E3 ubiquitin protein ligase 1
K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26] 
     11060 WWP2; WW domain containing E3 ubiquitin protein ligase 2
K05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26] 
     9320 TRIP12; thyroid hormone receptor interactor 12
K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26] 
     4734 NEDD4; NEDD4 E3 ubiquitin protein ligase
K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] 
     23327 NEDD4L; NEDD4 like E3 ubiquitin protein ligase
K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26] 
     10075 HUWE1; HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26] 
     9870 AREL1; apoptosis resistant E3 ubiquitin protein ligase 1
K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26] 
     51366 UBR5; ubiquitin protein ligase E3 component n-recognin 5
K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26] 
     55632 G2E3; G2/M-phase specific E3 ubiquitin protein ligase
K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26] 
     8925 HERC1; HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26] 
     8924 HERC2; HECT and RLD domain containing E3 ubiquitin protein ligase 2
K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
     8916 HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3
K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26] 
     26091 HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4
K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26] 
     57531 HACE1; HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26] 
     23072 HECW1; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
K12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26] 
     57520 HECW2; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26] 
     25831 HECTD1; HECT domain E3 ubiquitin protein ligase 1
K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26] 
     143279 HECTD2; HECT domain E3 ubiquitin protein ligase 2
K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26] 
     79654 HECTD3; HECT domain E3 ubiquitin protein ligase 3
K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26] 
     283450 HECTD4; HECT domain E3 ubiquitin protein ligase 4
K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26] 
     HECT type E3 associated proteins
   U-box type E3
   Single Ring-finger type E3
   Atypical E3
   UBL E3 ligases
   Multi subunit Ring-finger type E3
 
 Deubiquitinating enzyme (DUB)

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Last updated: April 5, 2024