1. Oxidoreductases
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2. Transferases
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3. Hydrolases
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4. Lyases
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5. Isomerases
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5.1 Racemases and epimerases
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5.2 cis-trans-Isomerases
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5.3 Intramolecular oxidoreductases
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5.4 Intramolecular transferases
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5.5 Intramolecular lyases
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5.5.1 Intramolecular lyases (only sub-subclass identified to date)
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5.5.1.1 muconate cycloisomerase
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5.5.1.2 3-carboxy-cis,cis-muconate cycloisomerase
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5.5.1.3 tetrahydroxypteridine cycloisomerase
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5.5.1.4 inositol-3-phosphate synthase
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5.5.1.5 carboxy-cis,cis-muconate cyclase
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5.5.1.6 chalcone isomerase
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5.5.1.7 chloromuconate cycloisomerase
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5.5.1.8 (+)-bornyl diphosphate synthase
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5.5.1.9 cycloeucalenol cycloisomerase
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5.5.1.10 alpha-pinene-oxide decyclase
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5.5.1.11 dichloromuconate cycloisomerase
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5.5.1.12 copalyl diphosphate synthase
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5.5.1.13 ent-copalyl diphosphate synthase
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5.5.1.14 syn-copalyl-diphosphate synthase
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5.5.1.15 terpentedienyl-diphosphate synthase
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5.5.1.16 halimadienyl-diphosphate synthase
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5.5.1.17 (S)-beta-macrocarpene synthase
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5.5.1.18 lycopene epsilon-cyclase
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5.5.1.19 lycopene beta-cyclase
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5.5.1.20 prosolanapyrone-III cycloisomerase
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5.5.1.22 (-)-bornyl diphosphate synthase
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5.5.1.23 aklanonic acid methyl ester cyclase
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5.5.1.24 tocopherol cyclase
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5.5.1.25 3,6-anhydro-L-galactonate cycloisomerase
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5.5.1.26 nogalonic acid methyl ester cyclase
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5.5.1.27 D-galactarolactone cycloisomerase
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5.5.1.28 (-)-kolavenyl diphosphate synthase
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5.5.1.29 (+)-kolavenyl diphosphate synthase
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5.5.1.30 labda-7,13-dienyl diphosphate synthase
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5.5.1.31 hapalindole H synthase
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5.5.1.32 12-epi-hapalindole U synthase
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5.5.1.33 12-epi-fischerindole U synthase
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5.5.1.34 (+)-cis,trans-nepetalactol synthase
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5.5.1.35 (+)-cis,cis-nepetalactol synthase
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5.5.1.36 hapalindole U synthase
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5.6 Isomerases altering macromolecular conformation
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5.99 Other isomerases
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6. Ligases
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7. Translocases
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