KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
   09121 Transcription
 
   09122 Translation
 
   09123 Folding, sorting and degradation
 
   09124 Replication and repair
     03030 DNA replication [PATH:ko03030]
       K02345  holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02342  dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02337  dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02343  dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02341  holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02340  holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02344  holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K02339  holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02338  dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02314  dnaB; replicative DNA helicase [EC:5.6.2.3]
       K02316  dnaG; DNA primase [EC:2.7.7.101]
       K03111  ssb; single-strand DNA-binding protein
       K03469  rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]
       K22316  rhnA-cobC; ribonuclease H / adenosylcobalamin/alpha-ribazole phosphatase [EC:3.1.26.4 3.1.3.73]
       K03470  rnhB; ribonuclease HII [EC:3.1.26.4]
       K03471  rnhC; ribonuclease HIII [EC:3.1.26.4]
       K02335  polA; DNA polymerase I [EC:2.7.7.7]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K02319  pol; DNA polymerase, archaea type [EC:2.7.7.7]
       K02323  polB; DNA polymerase II small subunit [EC:2.7.7.7]
       K02322  polC; DNA polymerase II large subunit [EC:2.7.7.7]
       K10726  mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
       K02683  priS, pri1, priA; DNA primase small subunit [EC:2.7.7.102]
       K18882  priL, pri2, priB; DNA primase large subunit
       K07466  RFA1, RPA1, rpa; replication factor A1
       K04802  PCNA; proliferating cell nuclear antigen
       K04801  rfcS; replication factor C small subunit
       K04800  rfcL; replication factor C large subunit
       K10742  DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
       K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.1.-.-]
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
       K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
       K02321  POLA2; DNA polymerase alpha subunit B
       K02684  PRI1; DNA primase small subunit [EC:2.7.7.102]
       K02685  PRI2; DNA primase large subunit
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K02540  MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
       K02541  MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
       K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:5.6.2.3]
       K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:5.6.2.3]
       K02542  MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:5.6.2.3]
       K10739  RFA2, RPA2; replication factor A2
       K10741  RPA4; replication factor A4
       K10740  RPA3; replication factor A3
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K10743  RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
       K10744  RNASEH2B; ribonuclease H2 subunit B
       K10745  RNASEH2C; ribonuclease H2 subunit C
     03410 Base excision repair [PATH:ko03410]
     03420 Nucleotide excision repair [PATH:ko03420]
     03430 Mismatch repair [PATH:ko03430]
       K03555  mutS; DNA mismatch repair protein MutS
       K07456  mutS2; DNA mismatch repair protein MutS2
       K03572  mutL; DNA mismatch repair protein MutL
       K03573  mutH; DNA mismatch repair protein MutH
       K03657  uvrD, pcrA; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
       K01141  sbcB, exoI; exodeoxyribonuclease I [EC:3.1.11.1]
       K03601  xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
       K03602  xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
       K10857  exoX; exodeoxyribonuclease X [EC:3.1.11.-]
       K07462  recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
       K03111  ssb; single-strand DNA-binding protein
       K02337  dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02343  dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02340  holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02345  holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02339  holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02344  holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K06223  dam; DNA adenine methylase [EC:2.1.1.72]
       K10858  PMS2; DNA mismatch repair protein PMS2
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08737  MSH6; DNA mismatch repair protein MSH6
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08739  MLH3; DNA mismatch repair protein MLH3
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K04802  PCNA; proliferating cell nuclear antigen
       K10746  EXO1; exonuclease 1 [EC:3.1.-.-]
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
     03440 Homologous recombination [PATH:ko03440]
       K07462  recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
       K03111  ssb; single-strand DNA-binding protein
       K03629  recF; DNA replication and repair protein RecF
       K03584  recO; DNA repair protein RecO (recombination protein O)
       K06187  recR; recombination protein RecR
       K03553  recA; recombination protein RecA
       K02335  polA; DNA polymerase I [EC:2.7.7.7]
       K03550  ruvA; holliday junction DNA helicase RuvA
       K03551  ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
       K01159  ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
       K03655  recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
       K03582  recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
       K03583  recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
       K03581  recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
       K02337  dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02343  dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02340  holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02345  holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02339  holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02344  holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K04066  priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
       K02686  priB; primosomal replication protein N
       K04067  priC; primosomal replication protein N''
       K02317  dnaT; DNA replication protein DnaT
       K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
       K10865  MRE11; double-strand break repair protein MRE11
       K10868  XRS2; DNA repair protein XRS2
       K10867  NBN, NBS1; nibrin
       K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
       K10605  BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
       K10683  BARD1; BRCA1-associated RING domain protein 1
       K20773  RBBP8, CTIP; DNA endonuclease RBBP8 [EC:3.1.-.-]
       K15362  BRIP1, BACH1, FANCJ; fanconi anemia group J protein [EC:5.6.2.3]
       K10728  TOPBP1; topoisomerase (DNA) II binding protein 1
       K20774  FAM175A, ABRA1; BRCA1-A complex subunit Abraxas
       K20775  UIMC1, RAP80; BRCA1-A complex subunit RAP80
       K20776  BABAM, NBA1, MERIT40; BRISC and BRCA1-A complex member 1
       K12173  BRE, BRCC45; BRCA1-A complex subunit BRE
       K11864  BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
       K10897  PALB2, FANCN; partner and localizer of BRCA2
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K10881  SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
       K19528  SYCP3; synaptonemal complex protein 3
       K10957  RAD55; DNA repair protein RAD55
       K10958  RAD57; DNA repair protein RAD57
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K04482  RAD51; DNA repair protein RAD51
       K10873  RAD52; DNA repair and recombination protein RAD52
       K10869  RAD51L1, RAD51B; RAD51-like protein 1
       K10870  RAD51L2, RAD51C; RAD51-like protein 2
       K10871  RAD51L3, RAD51D; RAD51-like protein 3
       K10879  XRCC2; DNA-repair protein XRCC2
       K10880  XRCC3; DNA-repair protein XRCC3
       K10959  RAD59; DNA repair protein RAD59
       K10875  RAD54L, RAD54; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
       K10877  RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K10901  BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4]
       K03165  TOP3; DNA topoisomerase III [EC:5.6.2.1]
       K08991  MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
       K10882  EME1, MMS4; crossover junction endonuclease EME1 [EC:3.1.22.-]
     03450 Non-homologous end-joining [PATH:ko03450]
     03460 Fanconi anemia pathway [PATH:ko03460]
 
   09126 Chromosome
 
   09125 Information processing in viruses
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:ko03000]
     03021 Transcription machinery [BR:ko03021]
     03019 Messenger RNA biogenesis [BR:ko03019]
     03041 Spliceosome [BR:ko03041]
     03011 Ribosome [BR:ko03011]
     03009 Ribosome biogenesis [BR:ko03009]
     03016 Transfer RNA biogenesis [BR:ko03016]
     03012 Translation factors [BR:ko03012]
     03110 Chaperones and folding catalysts [BR:ko03110]
     04131 Membrane trafficking [BR:ko04131]
     04121 Ubiquitin system [BR:ko04121]
     03051 Proteasome [BR:ko03051]
     03032 DNA replication proteins [BR:ko03032]
       K02603  ORC1; origin recognition complex subunit 1
       K02604  ORC2; origin recognition complex subunit 2
       K02605  ORC3; origin recognition complex subunit 3
       K02606  ORC4; origin recognition complex subunit 4
       K02607  ORC5; origin recognition complex subunit 5
       K02608  ORC6; origin recognition complex subunit 6
       K10727  CDT1; chromatin licensing and DNA replication factor 1
       K02213  CDC6; cell division control protein 6
       K02540  MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
       K02541  MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
       K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:5.6.2.3]
       K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:5.6.2.3]
       K02542  MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:5.6.2.3]
       K06627  CCNA; cyclin-A
       K06626  CCNE; G1/S-specific cyclin-E1
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]
       K06629  DBF4, ASK; protein DBF4
       K02309  DBF4; regulatory subunit for Cdc7p protein kinase
       K10732  GINS1, PSF1; GINS complex subunit 1
       K10733  GINS2, PSF2; GINS complex subunit 2
       K10734  GINS3; GINS complex subunit 3
       K10735  GINS4, SLD5; GINS complex subunit 4
       K03507  DPB11; DNA replication regulator DPB11
       K10728  TOPBP1; topoisomerase (DNA) II binding protein 1
       K10729  SLD2; DNA replication regulator SLD2
       K10730  RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
       K10731  SLD3; DNA replication regulator SLD3
       K06628  CDC45; cell division control protein 45
       K10737  MCM8; DNA helicase MCM8 [EC:5.6.2.4]
       K10738  MCM9; DNA helicase MCM9 [EC:5.6.2.4]
       K10736  MCM10; minichromosome maintenance protein 10
       K15254  HELB; DNA helicase B [EC:5.6.2.3]
       K24274  FAM111A; protein FAM111A
       K26052  CINP; cyclin-dependent kinase 2-interacting protein
       K26116  MTBP; Mdm2-binding protein
       K26117  TICRR; Treslin
       K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
       K02321  POLA2; DNA polymerase alpha subunit B
       K02684  PRI1; DNA primase small subunit [EC:2.7.7.102]
       K02685  PRI2; DNA primase large subunit
       K02324  POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02332  POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
       K02333  POLG2; DNA polymerase gamma 2
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K03469  rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]
       K10743  RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
       K10744  RNASEH2B; ribonuclease H2 subunit B
       K10745  RNASEH2C; ribonuclease H2 subunit C
       K04802  PCNA; proliferating cell nuclear antigen
       K10742  DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
       K19783  HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]
       K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.1.-.-]
       K10746  EXO1; exonuclease 1 [EC:3.1.-.-]
       K25861  ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
       K26118  ATAD5; ATPase family AAA domain-containing protein 5
       K00558  DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
       K17398  DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
       K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
       K10749  GMNN; geminin
       K26119  MCIDAS; multicilin
       K05868  CCNB1; G2/mitotic-specific cyclin-B1
       K21770  CCNB2; G2/mitotic-specific cyclin-B2
       K21771  CCNB3; G2/mitotic-specific cyclin-B3
       K21777  CCNB; G2/mitotic-specific cyclin-B, other
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K11109  POT1; protection of telomeres protein 1
       K11110  TERF1, TRF1; telomeric repeat-binding factor 1
       K11111  TERF2, TRF2; telomeric repeat-binding factor 2
       K11112  TINF2, TIN2; TERF1-interacting nuclear factor 2
       K11113  TERF2IP, RAP1; telomeric repeat-binding factor 2-interacting protein 1
       K11114  ACD, TPP1; adrenocortical dysplasia protein
       K25749  TERB1; telomere repeats-binding bouquet formation protein 1
       K25750  TERB2; telomere repeats-binding bouquet formation protein 2
       K25751  MAJIN; membrane-anchored junction protein
       K23311  CTC1; CST complex subunit CTC1
       K23312  STN1; CST complex subunit STN1
       K23313  TEN1; CST complex subunit TEN1
       K11115  CDC13; cell division control protein 13
       K11117  STN1; protein STN1
       K11116  TEN1; telomere length regulation protein
       K11118  RIF1; RAP1-interacting factor 1
       K11119  RIF2; RAP1-interacting factor 2
       K11120  SIR1; regulatory protein SIR1
       K11121  SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
       K11122  SIR3; regulatory protein SIR3
       K11123  SIR4; regulatory protein SIR4
       K09426  RAP1; Myb-like DNA-binding protein RAP1
       K11124  SMG6, EST1A; protein SMG6 [EC:3.1.-.-]
       K11125  SMG5, EST1B; protein SMG5
       K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
       K11127  TEP1; telomerase protein component 1
       K11128  GAR1, NOLA1; H/ACA ribonucleoprotein complex subunit 1
       K11129  NHP2, NOLA2; H/ACA ribonucleoprotein complex subunit 2
       K11130  NOP10, NOLA3; H/ACA ribonucleoprotein complex subunit 3
       K11131  DKC1, NOLA4, CBF5; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
       K11132  EST1; telomere elongation protein [EC:2.7.7.-]
       K11133  EST3; telomere replication protein
       K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
       K11087  SNRPD1, SMD1; small nuclear ribonucleoprotein D1
       K11096  SNRPD2, SMD2; small nuclear ribonucleoprotein D2
       K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
       K11097  SNRPE, SME; small nuclear ribonucleoprotein E
       K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
       K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
       K11134  ELG1; telomere length regulation protein
       K10865  MRE11; double-strand break repair protein MRE11
       K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
       K10867  NBN, NBS1; nibrin
       K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
       K10900  WRN, RECQL2; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
       K10901  BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4]
       K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
       K10848  ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
       K24070  PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
       K10798  PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
       K10799  TNKS; tankyrase [EC:2.4.2.30]
       K11135  PINX1; Pin2-interacting protein X1
       K11136  RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
       K11137  TELO2, TEL2; telomere length regulation protein
       K01149  TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]
       K11138  RIF1; telomere-associated protein RIF1
       K15255  PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
       K21772  PURA; transcriptional activator protein Pur-alpha
       K21800  PURG; purine-rich element-binding protein gamma
       K23314  WRAP53, TCAB1; telomerase Cajal body protein 1
       K25059  SDE2; replication stress response regulator SDE2
       K25186  RTF2; replication termination factor 2
       K22485  TBF1; protein TBF1
       K03163  TOP1; DNA topoisomerase I [EC:5.6.2.1]
       K03164  TOP2; DNA topoisomerase II [EC:5.6.2.2]
       K03165  TOP3; DNA topoisomerase III [EC:5.6.2.1]
       K05787  hupA; DNA-binding protein HU-alpha
       K03530  hupB; DNA-binding protein HU-beta
       K04764  ihfA, himA; integration host factor subunit alpha
       K05788  ihfB, himD; integration host factor subunit beta
       K02313  dnaA; chromosomal replication initiator protein
       K02314  dnaB; replicative DNA helicase [EC:5.6.2.3]
       K02315  dnaC; DNA replication protein DnaC
       K02316  dnaG; DNA primase [EC:2.7.7.101]
       K03346  dnaB; replication initiation and membrane attachment protein
       K11144  dnaI; primosomal protein DnaI
       K18996  repC; replication initiation protein RepC
       K03111  ssb; single-strand DNA-binding protein
       K10725  cdc6A; archaeal cell division control protein 6
       K10726  mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
       K02683  priS, pri1, priA; DNA primase small subunit [EC:2.7.7.102]
       K18882  priL, pri2, priB; DNA primase large subunit
       K09723  ginS; DNA replication factor GINS
       K02337  dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02339  holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02340  holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02343  dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02344  holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K02345  holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K22316  rhnA-cobC; ribonuclease H / adenosylcobalamin/alpha-ribazole phosphatase [EC:3.1.26.4 3.1.3.73]
       K03470  rnhB; ribonuclease HII [EC:3.1.26.4]
       K03471  rnhC; ribonuclease HIII [EC:3.1.26.4]
       K02335  polA; DNA polymerase I [EC:2.7.7.7]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K23786  exoA; 5'-3' exonuclease [EC:3.1.11.-]
       K02319  pol; DNA polymerase, archaea type [EC:2.7.7.7]
       K02322  polC; DNA polymerase II large subunit [EC:2.7.7.7]
       K02323  polB; DNA polymerase II small subunit [EC:2.7.7.7]
       K04800  rfcL; replication factor C large subunit
       K04801  rfcS; replication factor C small subunit
       K10748  tus, tau; DNA replication terminus site-binding protein
       K06223  dam; DNA adenine methylase [EC:2.1.1.72]
       K03645  seqA; negative modulator of initiation of replication
       K10763  hda; DnaA-homolog protein
       K02469  gyrA; DNA gyrase subunit A [EC:5.6.2.2]
       K02470  gyrB; DNA gyrase subunit B [EC:5.6.2.2]
       K02621  parC; topoisomerase IV subunit A [EC:5.6.2.2]
       K02622  parE; topoisomerase IV subunit B [EC:5.6.2.2]
       K03166  top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
       K03167  top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
       K03168  topA; DNA topoisomerase I [EC:5.6.2.1]
       K03169  topB; DNA topoisomerase III [EC:5.6.2.1]
       K03170  topG, rgy; reverse gyrase [EC:5.6.2.2 5.6.2.-]
     03036 Chromosome and associated proteins [BR:ko03036]
     03400 DNA repair and recombination proteins [BR:ko03400]
       K00567  ogt, MGMT; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
       K10859  ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
       K10860  ALKBH3, DEPC1; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
       K18663  ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
       K01669  phr, PHR1; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
       K03648  UNG, UDG; uracil-DNA glycosylase [EC:3.2.2.27]
       K10861  UDG2, CCNO; uracil-DNA glycosylase 2 [EC:3.2.2.-]
       K20813  TDG; thymine-DNA glycosylase [EC:3.2.2.29]
       K03652  MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
       K10800  SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
       K03575  mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
       K10801  MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
       K03660  OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
       K10567  NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
       K10568  NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
       K10569  NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
       K10773  NTHL1, nth; endonuclease III [EC:3.2.2.- 4.2.99.18]
       K10771  APEX1; AP endonuclease 1 [EC:3.1.11.2]
       K10772  APEX2; AP endonuclease 2 [EC:3.1.11.2]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K04802  PCNA; proliferating cell nuclear antigen
       K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.1.-.-]
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K10803  XRCC1; DNA-repair protein XRCC1
       K10776  LIG3; DNA ligase 3 [EC:6.5.1.1]
       K10862  TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
       K10863  APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
       K13295  APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
       K08073  PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
       K08075  E3.1.3.32; polynucleotide 3'-phosphatase [EC:3.1.3.32]
       K10802  HMGB1; high mobility group protein B1
       K03512  POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
       K24070  PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
       K10798  PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
       K10838  XPC; xeroderma pigmentosum group C-complementing protein
       K10839  RAD23, HR23; UV excision repair protein RAD23
       K10840  CETN2; centrin-2
       K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
       K10609  CUL4; cullin 4
       K10610  DDB1; DNA damage-binding protein 1
       K10140  DDB2; DNA damage-binding protein 2
       K15082  RAD7; DNA repair protein RAD7
       K15083  RAD16; DNA repair protein RAD16
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03013  RPABC1, RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPABC2, RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03016  RPABC3, RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03007  RPABC5, RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03009  RPABC4, RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K10570  ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8
       K10841  ERCC6, CSB, RAD26; DNA excision repair protein ERCC-6
       K23720  UVSSA; UV-stimulated scaffold protein A
       K25829  ELOF1, ELF1; transcription elongation factor 1
       K10843  ERCC3, XPB; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
       K10844  ERCC2, XPD; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
       K03141  TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
       K03142  TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
       K03143  TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
       K03144  TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
       K10845  TTDA, GTF2H5, TFB5; TFIIH basal transcription factor complex TTD-A subunit
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K06634  CCNH; cyclin H
       K10842  MNAT1; CDK-activating kinase assembly factor MAT1
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K10847  XPA; DNA-repair protein complementing XP-A cells
       K10849  ERCC1; DNA excision repair protein ERCC-1
       K10848  ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
       K10846  ERCC5, XPG, RAD2; DNA excision repair protein ERCC-5
       K15075  MET18, MMS19; DNA repair/transcription protein MET18/MMS19
       K03869  CUL3; cullin 3
       K10612  CUL5; cullin 5
       K03872  ELOC, TCEB1; elongin-C
       K03873  ELOB, TCEB2; elongin-B
       K15076  ELOA, TCEB3; elongin-A
       K15077  ELA1; elongin-A
       K26545  UBAP2; ubiquitin-associated protein 2
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K10864  PMS1; DNA mismatch repair protein PMS1
       K08734  MLH1; DNA mismatch repair protein MLH1
       K10858  PMS2; DNA mismatch repair protein PMS2
       K08739  MLH3; DNA mismatch repair protein MLH3
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K10746  EXO1; exonuclease 1 [EC:3.1.-.-]
       K24755  WDR76, CMR1; WD repeat-containing protein 76
       K10865  MRE11; double-strand break repair protein MRE11
       K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
       K10867  NBN, NBS1; nibrin
       K10868  XRS2; DNA repair protein XRS2
       K10605  BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
       K10683  BARD1; BRCA1-associated RING domain protein 1
       K20774  FAM175A, ABRA1; BRCA1-A complex subunit Abraxas
       K20775  UIMC1, RAP80; BRCA1-A complex subunit RAP80
       K20776  BABAM, NBA1, MERIT40; BRISC and BRCA1-A complex member 1
       K12173  BRE, BRCC45; BRCA1-A complex subunit BRE
       K11864  BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
       K15362  BRIP1, BACH1, FANCJ; fanconi anemia group J protein [EC:5.6.2.3]
       K10728  TOPBP1; topoisomerase (DNA) II binding protein 1
       K20773  RBBP8, CTIP; DNA endonuclease RBBP8 [EC:3.1.-.-]
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K10897  PALB2, FANCN; partner and localizer of BRCA2
       K04482  RAD51; DNA repair protein RAD51
       K10869  RAD51L1, RAD51B; RAD51-like protein 1
       K10870  RAD51L2, RAD51C; RAD51-like protein 2
       K10871  RAD51L3, RAD51D; RAD51-like protein 3
       K10879  XRCC2; DNA-repair protein XRCC2
       K10880  XRCC3; DNA-repair protein XRCC3
       K10957  RAD55; DNA repair protein RAD55
       K10958  RAD57; DNA repair protein RAD57
       K10873  RAD52; DNA repair and recombination protein RAD52
       K10874  RDM1, RAD52B; RAD52 motif-containing protein 1
       K26556  RAD52-1; DNA repair RAD52-like protein 1, mitochondrial
       K26558  RAD52-2; DNA repair RAD52-like protein 2, chloroplastic
       K10959  RAD59; DNA repair protein RAD59
       K10875  RAD54L, RAD54; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
       K10876  RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
       K10877  RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
       K10899  RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
       K10900  WRN, RECQL2; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
       K10901  BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4]
       K10730  RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
       K10902  RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
       K03165  TOP3; DNA topoisomerase III [EC:5.6.2.1]
       K10990  RMI1, BRAP75; RecQ-mediated genome instability protein 1
       K15364  NCE4, RMI1; RecQ-mediated genome instability protein 1
       K15365  RMI2; RecQ-mediated genome instability protein 2
       K15423  PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
       K15424  PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
       K15425  PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
       K17491  SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
       K15426  PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
       K19022  AP5B1; AP-5 complex subunit beta-1
       K19023  AP5M1, MUDENG; AP-5 complex subunit mu-1
       K19024  AP5S1; AP-5 complex subunit sigma-1
       K19025  AP5Z1, SPG48; AP-5 complex subunit zeta-1
       K22803  SMC5; structural maintenance of chromosomes protein 5
       K22804  SMC6; structural maintenance of chromosomes protein 6
       K22805  FAM84A, NSE1; protein FAM84A
       K22817  NSMCE1, NSE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
       K22756  NSMCE2, NSE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
       K22823  NSMCE3, NSE3; non-structural maintenance of chromosomes element 3
       K22825  NSMCE4, NSE4; non-structural maintenance of chromosomes element 4
       K22826  EID3, NSMCE4B; EP300-interacting inhibitor of differentiation 3
       K26126  SLF1; SMC5-SMC6 complex localization factor protein 1
       K26127  SLF2; SMC5-SMC6 complex localization factor protein 2
       K10882  EME1, MMS4; crossover junction endonuclease EME1 [EC:3.1.22.-]
       K10883  EME2; crossover junction endonuclease EME2
       K20777  EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
       K08991  MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
       K10881  SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
       K10991  SWI5, SAE3; DNA repair protein Swi5/Sae3
       K10992  SFR1; Swi5-dependent recombination DNA repair protein 1
       K15078  SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
       K10484  BTBD12, SLX4; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
       K15079  SLX4; structure-specific endonuclease subunit SLX4
       K15338  GEN1, YEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
       K19026  SPG11; spatacsin
       K19027  ZFYVE26; zinc finger FYVE domain-containing protein 26
       K20778  RAD51AP1; RAD51-associated protein 1
       K11339  MORF4L1, MRG15, EAF3; mortality factor 4-like protein 1
       K22544  SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
       K22766  FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
       K22806  SPIDR; DNA repair-scaffolding protein
       K22810  FAM84B; protein FAM84B
       K23112  BRAT1; BRCA1-associated ATM activator 1
       K23456  CFAP410, C21ORF2; cilla- and flagella-associated protein
       K25065  HDGFL2; hepatoma-derived growth factor-related protein 2
       K25770  ZSWIM7, SWS1; zinc finger SWIM domain-containing protein 7
       K25771  SWSAP1; ATPase SWSAP1
       K25790  EMSY; BRCA2-interacting transcriptional repressor EMSY
       K25791  HSF2BP; heat shock factor 2-binding protein
       K26125  MMS22L; protein MMS22-like
       K09257  NFKBIL2; NF-kappa-B inhibitor-like protein 2
       K27262  BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
       K27412  PARPBP; PCNA-interacting partner
       K22807  WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]
       K22685  WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
       K26559  WHY1; single-stranded DNA-binding protein WHY1
       K26561  WHY2; single-stranded DNA-binding protein WHY2
       K26560  WHY3; single-stranded DNA-binding protein WHY3
       K14635  MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
       K15080  SAW1; single-strand annealing weakened protein 1
       K26124  RTT101, CUL8; cullin 8
       K26122  MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
       K26123  MMS1; E3 ubiquitin-protein ligase linker protein MMS1
       K10884  XRCC6, KU70, G22P1; ATP-dependent DNA helicase 2 subunit 1
       K10885  XRCC5, KU80, G22P2; ATP-dependent DNA helicase 2 subunit 2
       K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
       K10777  LIG4, DNL4; DNA ligase 4 [EC:6.5.1.1]
       K10886  XRCC4; DNA-repair protein XRCC4
       K10980  NHEJ1, XLF; non-homologous end-joining factor 1
       K10982  LIF1; ligase-interacting factor 1
       K10983  NEJ1, LIF2; non-homologous end-joining protein 1
       K03513  POLM; DNA polymerase mu [EC:2.7.7.7]
       K00977  DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
       K10981  POL4; DNA polymerase IV [EC:2.7.7.7]
       K10887  DCLRE1C, ARTEMIS, SCIDA; DNA cross-link repair 1C protein [EC:3.1.-.-]
       K19619  TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
       K23113  SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
       K23386  PWWP3, MUM1; PWWP domain-containing DNA repair factor 3
       K25772  PAXX; protein PAXX
       K26155  CYREN, MRI; cell cycle regulator of non-homologous end joining
       K25792  JMJD8; jumonji domain-containing protein 8
       K26128  SHLD1; shieldin complex subunit 1
       K26129  SHLD2; shieldin complex subunit 2
       K26130  SHLD3; shieldin complex subunit 3
       K10888  FANCA; fanconi anemia group A protein
       K10889  FANCB; fanconi anemia group B protein
       K10890  FANCC; fanconi anemia group C protein
       K10892  FANCE; fanconi anemia group E protein
       K10893  FANCF; fanconi anemia group F protein
       K10894  FANCG; fanconi anemia group G protein
       K10606  FANCL, PHF9; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
       K10896  FANCM; fanconi anemia group M protein
       K10898  FAAP24; fanconi anemia-associated protein
       K10993  FAAP100; fanconi anemia core complex 100 kDa subunit
       K06054  HES1; hairy and enhancer of split 1
       K11511  APITD1, CENPS, MHF1; centromere protein S
       K15360  STRA13, CENPX, MHF2; centromere protein X
       K13960  UBE2T, HSPC150; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
       K10891  FANCD2; fanconi anemia group D2 protein
       K10895  FANCI; fanconi anemia group I protein
       K15363  FAN1, MTMR15; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
       K11137  TELO2, TEL2; telomere length regulation protein
       K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
       K15361  WDR48, UAF1; WD repeat-containing protein 48
       K15498  PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
       K15499  PPP6R1, SAPS1; serine/threonine-protein phosphatase 6 regulatory subunit 1
       K15500  PPP6R2, SAPS2; serine/threonine-protein phosphatase 6 regulatory subunit 2
       K15501  PPP6R3, SAPS3; serine/threonine-protein phosphatase 6 regulatory subunit 3
       K15502  ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
       K15503  ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
       K15504  ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
       K10667  RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
       K20779  RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
       K20805  RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
       K10595  HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
       K23314  WRAP53, TCAB1; telomerase Cajal body protein 1
       K24164  TPRN; taperin
       K24688  ZCWPW1; zinc finger CW-type PWWP domain protein 1
       K24752  WDR70; WD repeat-containing protein 70
       K03509  POLH; DNA polymerase eta [EC:2.7.7.7]
       K03510  POLI; DNA polymerase iota [EC:2.7.7.7]
       K03511  POLK; DNA polymerase kappa [EC:2.7.7.7]
       K03515  REV1; DNA repair protein REV1 [EC:2.7.7.-]
       K02350  REV3L, POLZ; DNA polymerase zeta [EC:2.7.7.7]
       K03508  POLZ2, rev7; DNA polymerase zeta [EC:2.7.7.7]
       K16618  POLN; DNA polymerase nu [EC:2.7.7.7]
       K10573  UBE2A, UBC2, RAD6A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
       K10574  UBE2B, RAD6B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
       K10627  RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
       K15505  RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
       K15711  SMARCA3, HLTF; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
       K10704  UBE2V; ubiquitin-conjugating enzyme E2 variant
       K10580  UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
       K24051  SPRTN; SprT-like domain-contaning protein Spartan
       K26957  GCNA, ACRC; germ cell nuclear acidic protein
       K10994  RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
       K10995  RAD9B; cell cycle checkpoint control protein RAD9B
       K10903  HUS1; HUS1 checkpoint protein
       K10996  HUS1B; checkpoint protein HUS1B
       K02830  HRAD1, RAD17; cell cycle checkpoint protein [EC:3.1.11.2]
       K06662  HRAD17, RAD24; cell cycle checkpoint protein
       K02544  MEC3; G2-specific checkpoint protein
       K06663  DDC1; DNA damage checkpoint protein
       K10997  TIMELESS, TOF1, SWI1; replication fork protection complex subunit TIMELESS/Tof1/Swi1
       K10998  TIPIN, CSM3, SWI3; replication fork protection complex subunit TIPIN/Csm3/Swi3
       K25773  CLSPN; claspin
       K11272  MRC1; mediator of replication checkpoint protein 1
       K20403  TTI1; TELO2-interacting protein 1
       K23115  TTI2; TELO2-interacting protein 2
       K23390  BAG6; large proline-rich protein BAG6
       K23388  UBL4; ubiquitin-like protein 4
       K23387  GET4; golgi to ER traffic protein 4
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K10905  ATRIP; ATR interacting protein
       K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02216  CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
       K06641  CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K02555  MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K06630  YWHAE; 14-3-3 protein epsilon
       K19483  NAV2; neuron navigator 2 [EC:5.6.2.4]
       K06632  WEE1; wee1-like protein kinase [EC:2.7.11.1]
       K02831  RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
       K21944  PER1; period circadian protein 1
       K02633  PER2; period circadian protein 2
       K21945  PER3; period circadian protein 3
       K06661  RAD9; DNA repair protein RAD9
       K20780  MDC1; mediator of DNA damage checkpoint protein 1
       K02543  MEC1; cell cycle checkpoint protein MEC1
       K15081  AMN1; antagonist of mitotic exit network protein 1
       K17336  PLS3; plastin-3
       K18340  AEN, ISG20L1; apoptosis-enhancing nuclease [EC:3.1.-.-]
       K08862  PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
       K19596  PLK5; inactive serine/threonine-protein kinase PLK5
       K08857  NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
       K20879  NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
       K20880  NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
       K03114  SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
       K24663  NDD1; nuclear division defective protein 1
       K24664  FKH; forkhead protein FKH
       K22422  DONSON; protein downstream neighbor of Son
       K22808  KANK; KN motif and ankyrin repeat domain-containing protein
       K23389  KLLN; killin
       K24458  SLFN11; schlafen family member 11 [EC:3.6.-.-]
       K24782  CHMP4C, SNF7, VPS32C; charged multivesicular body protein 4C
       K12196  VPS4; vacuolar protein-sorting-associated protein 4
       K24778  ZFYVE19, ANCHR; abscission/NoCut checkpoint regulator
       K25059  SDE2; replication stress response regulator SDE2
       K24770  DSE1, ALT2, EMB2757; protein decreased size exclusion limit 1
       K02349  POLQ; DNA polymerase theta [EC:2.7.7.7]
       K02331  POL5, MYBBP1A; DNA polymerase phi [EC:2.7.7.7]
       K22761  PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
       K10790  TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
       K10791  TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
       K15340  DCLRE1A, SNM1A, PSO2; DNA cross-link repair 1A protein
       K15341  DCLRE1B, SNM1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
       K17815  EXO5; exonuclease V [EC:3.1.-.-]
       K21813  ENDOV; endonuclease V [EC:3.1.26.-]
       K25861  ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
       K21411  ANKLE1, LEM3; ankyrin repeat and LEM domain-containing protein 1
       K05986  NUCS; nuclease S1 [EC:3.1.30.1]
       K19178  HELQ; POLQ-like helicase [EC:5.6.2.4]
       K20098  ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
       K10599  PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
       K12860  CDC5L, CDC5, CEF1; pre-mRNA-splicing factor CDC5/CEF1
       K12861  BCAS2; pre-mRNA-splicing factor SPF27
       K12862  PLRG1, PRL1, PRP46; pleiotropic regulator 1
       K03574  mutT, NUDT15, MTH2; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
       K17816  NUDT1, MTH1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
       K17817  NUDT18, MTH3; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
       K01520  dut, DUT; dUTP diphosphatase [EC:3.6.1.23]
       K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
       K10808  RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
       K10778  ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
       K13530  adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
       K13531  adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
       K06876  phrB; (6-4)DNA photolyase [EC:4.1.99.13]
       K03919  alkB; DNA oxidative demethylase [EC:1.14.11.33]
       K03649  mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
       K21929  udg; uracil-DNA glycosylase [EC:3.2.2.27]
       K01247  alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
       K13529  ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
       K01246  tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
       K10563  mutM, fpg; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
       K05522  nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
       K01142  E3.1.11.2, xthA; exodeoxyribonuclease III [EC:3.1.11.2]
       K01151  nfo; deoxyribonuclease IV [EC:3.1.21.2]
       K05982  E3.1.21.7, nfi; deoxyribonuclease V [EC:3.1.21.7]
       K07462  recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K02335  polA; DNA polymerase I [EC:2.7.7.7]
       K03701  uvrA; excinuclease ABC subunit A
       K03702  uvrB; excinuclease ABC subunit B
       K03703  uvrC; excinuclease ABC subunit C
       K05984  cho; excinuclease Cho [EC:3.1.25.-]
       K03657  uvrD, pcrA; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
       K03043  rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
       K03046  rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
       K13797  rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
       K03040  rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
       K03048  rpoE; DNA-directed RNA polymerase subunit delta
       K03060  rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
       K03723  mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
       K03555  mutS; DNA mismatch repair protein MutS
       K07456  mutS2; DNA mismatch repair protein MutS2
       K03572  mutL; DNA mismatch repair protein MutL
       K03573  mutH; DNA mismatch repair protein MutH
       K01141  sbcB, exoI; exodeoxyribonuclease I [EC:3.1.11.1]
       K03601  xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
       K03602  xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
       K10857  exoX; exodeoxyribonuclease X [EC:3.1.11.-]
       K02337  dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02339  holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02340  holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02343  dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02344  holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K02345  holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K03111  ssb; single-strand DNA-binding protein
       K06223  dam; DNA adenine methylase [EC:2.1.1.72]
       K07458  vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
       K03582  recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
       K03583  recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
       K03581  recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
       K03553  recA; recombination protein RecA
       K03550  ruvA; holliday junction DNA helicase RuvA
       K03551  ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
       K01159  ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
       K01160  rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
       K04066  priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
       K02686  priB; primosomal replication protein N
       K04067  priC; primosomal replication protein N''
       K02317  dnaT; DNA replication protein DnaT
       K03546  sbcC, rad50; DNA repair protein SbcC/Rad50
       K03547  sbcD, mre11; DNA repair protein SbcD/Mre11
       K04485  radA, sms; DNA repair protein RadA/Sms
       K03629  recF; DNA replication and repair protein RecF
       K03655  recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
       K03584  recO; DNA repair protein RecO (recombination protein O)
       K06187  recR; recombination protein RecR
       K03631  recN; DNA repair protein RecN (Recombination protein N)
       K03700  recU; recombination protein U
       K03554  rdgC; recombination associated protein RdgC
       K16898  addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
       K16899  addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
       K15342  cas1; CRISP-associated protein Cas1
       K19789  radD; DNA repair protein RadD
       K04483  radA; DNA repair protein RadA
       K04484  radB; DNA repair protein RadB
       K03552  hjr, hjc, hje; holliday junction resolvase [EC:3.1.21.10]
       K06915  herA; DNA double-strand break repair helicase HerA and related ATPase
       K25510  nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
       K03726  helS; ATP-dependent DNA helicase [EC:5.6.2.4]
       K10979  ku; DNA end-binding protein Ku
       K01971  ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
       K02469  gyrA; DNA gyrase subunit A [EC:5.6.2.2]
       K02470  gyrB; DNA gyrase subunit B [EC:5.6.2.2]
       K03168  topA; DNA topoisomerase I [EC:5.6.2.1]
       K05787  hupA; DNA-binding protein HU-alpha
       K03530  hupB; DNA-binding protein HU-beta
       K10906  recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
       K07455  recT; recombination protein RecT
       K03557  fis; Fis family transcriptional regulator, factor for inversion stimulation protein
       K04764  ihfA, himA; integration host factor subunit alpha
       K05788  ihfB, himD; integration host factor subunit beta
       K03654  recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
       K03746  hns; DNA-binding protein H-NS
       K02346  dinB; DNA polymerase IV [EC:2.7.7.7]
       K03502  umuC; DNA polymerase V
       K03503  umuD; DNA polymerase V [EC:3.4.21.-]
       K04479  dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
       K01356  lexA; repressor LexA [EC:3.4.21.88]
       K02336  polB; DNA polymerase II [EC:2.7.7.7]
       K14160  imuA; protein ImuA
       K14161  imuB; protein ImuB
       K14162  dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
       K14623  dinD; DNA-damage-inducible protein D
       K12149  dinI; DNA-damage-inducible protein I
       K03565  recX; regulatory protein
       K01157  rpnA; recombination-promoting nuclease RpnA [EC:3.1.21.-]
       K24087  rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
       K24088  rpnC; recombination-promoting nuclease RpnC [EC:3.1.21.-]
       K24089  rpnD; recombination-promoting nuclease RpnD [EC:3.1.21.-]
       K24090  rpnE; recombination-promoting nuclease RpnE
       K02347  polX, dpx; DNA polymerase (family X)
       K03656  rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
       K03658  helD; DNA helicase IV [EC:5.6.2.4]
       K03722  dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
       K03724  lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
       K23258  mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
       K01554  K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
       K00525  E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
       K00526  E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
       K06881  nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
       K22585  nreA; DNA repair protein NreA
     03029 Mitochondrial biogenesis [BR:ko03029]
 
   09183 Protein families: signaling and cellular processes
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 22, 2024