 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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 K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04852 CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K08018 RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
K08052 NF1; neurofibromin 1
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04370 LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04375 ELK1; ETS domain-containing protein Elk-1
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04377 MYC; Myc proto-oncogene protein
K04378 SRF; serum response factor
K04379 FOS; proto-oncogene protein c-fos
K04380 MAPT, TAU; microtubule-associated protein tau
K04381 STMN1; stathmin 1
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04391 CD14; monocyte differentiation antigen CD14
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02308 DAXX; death-associated protein 6
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
K04406 MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K04408 MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K04411 STK4, MST1; serine/threonine kinase 4
K04412 STK3, MST2; serine/threonine kinase 3
K04414 MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K17534 MLK4, KIAA1804; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04423 MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K04424 ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04425 MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04434 MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
K04435 MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
K04436 MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
K04437 FLNA; filamin-A
K04438 CRK, CRKII; C-crk adapter molecule crk
K04439 ARRB; beta-arrestin
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04442 MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04451 TP53, P53; tumor protein p53
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K04453 MAX; Max protein
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K04455 HSPB1; heat shock protein beta-1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04457 PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
K04458 PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
K18018 PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
K18019 PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K18498 DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K17614 DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
K04460 PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
K04461 PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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K12377 TSL; torso-like protein
K20226 TRK; protein trunk
K20227 FS1M3; female sterile (1) M3, polehole
K20228 FS1N; female sterile (1) Nasrat
K12378 TOR; tyrosine-protein kinase receptor torso [EC:2.7.10.1]
K02104 AOS; protein giant-lens (argos)
K16690 VN; protein vein
K20229 SPI; protein spitz
K02447 GRK; protein gruken
K16691 KRN; keren
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K20230 KEK1; kekkon-1
K04623 BOSS; bride of sevenless protein
K05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K04364 GRB2; growth factor receptor-bound protein 2
K20231 DOS; protein daughter of sevenless
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K17383 SPRY2; protein sprouty homolog 2
K07827 KRAS, KRAS2; GTPase KRas
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K12380 RASA3; Ras GTPase-activating protein 3
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K17536 CNKSR2, CNK2, KSR2; connector enhancer of kinase suppressor of Ras 2
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K20220 PTP-ER; tyrosine-protein phosphatase ERK [EC:3.1.3.48]
K20223 IPO7, RANBP7; importin-7
K20225 CIC; capicua transcriptional repressor
K08545 NR2E1, TLX, tll; nuclear receptor subfamily 2 group E member 1
K04497 GRO, TLE; groucho
K12379 HKB; huckebein
K02678 ETS1, pnt; C-ets-1
K03211 ETV6_7, yan; ETS translocation variant 6/7
K20232 EDL; ETS-domain lacking
K14290 XPO1, CRM1; exportin-1
K09237 TTK; tramtrack
K20233 PHYL; phyllopod
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K04508 TBL1; transducin (beta)-like 1
K06689 UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K20214 LZ; RUNX transcription factor Lozenge
K20211 PROX1; prospero homeobox 1
K16678 EGR; eiger
K16679 WGN; wengen
K20234 DOK2; docking protein 2
K08892 FRK, PTK5; fyn-related kinase [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04461 PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K17608 STRN1_3_4; striatin 1/3/4
K04448 JUN; transcription factor AP-1
K09031 FOSLN; fos-like antigen, invertebrate
K20210 RREB1; ras-responsive element-binding protein 1
K20235 RAW; raw
K04662 BMP4; bone morphogenetic protein 4
K05759 PFN; profilin
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K20016 HID; cell death protein hid
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K13411 DUOX, THOX; dual oxidase [EC:1.6.3.1 1.11.1.-]
K10176 TBX2; T-box protein 2
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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K11234 MFAL; mating pheromone alpha-factor
K11235 MFA; mating pheromone A-factor
K01383 BAR1; barrierpepsin [EC:3.4.23.35]
K11213 STE2; pheromone alpha factor receptor
K04627 STE3; pheromone a factor receptor
K02218 CSNK1, CKI; casein kinase 1 [EC:2.7.11.1]
K10591 NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K19860 GPA1; guanine nucleotide-binding protein alpha-1 subunit
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K07973 GNG; guanine nucleotide-binding protein subunit gamma, fungi
K19838 SST2; GTPase-activating protein SST2
K11236 CDC24; cell division control protein 24
K04393 CDC42; cell division control protein 42
K19839 RGA1_2; Rho-type GTPase-activating protein 1/2
K19840 BEM3; Rho-type GTPase-activating protein
K11237 BEM1; bud emergence protein 1
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K19833 CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
K11238 BNI1; cytokinesis protein
K11228 STE11; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K19841 STE50; protein STE50
K11239 STE5; pheromone-response scaffold protein
K11226 STE7; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K19806 PTP2_3; tyrosine-protein phosphatase 2/3 [EC:3.1.3.48]
K11240 MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]
K19812 SDP1; dual-specificity protein phosphatase SDP1 [EC:3.1.3.48]
K11215 STE12; transcription factor STE12
K11241 DIG1; down-regulator of invasive growth 1
K11242 DIG2; down-regulator of invasive growth 2
K12412 MCM1; pheromone receptor transcription factor
K11243 FUS1; nuclear fusion protein
K06652 FAR1; cyclin-dependent kinase inhibitor FAR1
K12760 CLN1; G1/S-specific cyclin CLN1
K06650 CLN2; G1/S-specific cyclin CLN2
K04563 CDC28, CDC2; cyclin-dependent kinase [EC:2.7.11.22]
K11244 WSC; cell wall integrity and stress response component
K11245 MID2, MTL1; mating pheromone-induced death protein 2
K19842 ROM1_2; RHO1 GDP-GTP exchange protein 1/2
K19843 TUS1; Rho1 guanine nucleotide exchange factor TUS1
K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K04513 RHOA; Ras homolog gene family, member A
K19844 BEM2; GTPase-activating protein BEM2
K19845 SAC7; GTPase-activating protein SAC7
K17971 BNR1; BNI1-related protein 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K11229 BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K08294 MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K19846 SPA2; protein SPA2
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19847 MLP1, KDX1; MPK-like protein 1
K09265 RLM1; transcription factor RLM1
K00706 E2.4.1.34; 1,3-beta-glucan synthase [EC:2.4.1.34]
K15174 PAF1; RNA polymerase II-associated factor 1
K06649 SWI4; regulatory protein SWI4
K06648 SWI6; regulatory protein SWI6
K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
K02220 CLB1; G2/mitotic-specific cyclin 1
K23469 CLB2; G2/mitotic-specific cyclin 2
K19848 HKR1; signaling mucin HKR1
K19849 MSB2; signaling mucin MSB2
K11246 SHO1; SHO1 osmosensor
K19850 OPY2; protein OPY2
K11231 SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
K11232 YPD1; osomolarity two-component system, phosphorelay intermediate protein YPD1
K11233 SSK1; osomolarity two-component system, response regulator SSK1
K11230 SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K11227 PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K19704 PTC1; protein phosphatase PTC1 [EC:3.1.3.16]
K19815 HOT1; high-osmolarity-induced transcription protein 1
K19807 SMP1; transcription factor SMP1
K00006 GPD1; glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]
K09468 MSN2_4; zinc finger protein MSN2/4
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K09051 SKO1, ATF1, PCR1; ATF/CREB family transcription factor
K06665 SSN6, CYC8; general transcriptional corepressor CYC8
K06666 TUP1; general transcriptional corepressor TUP1
K17741 GRE2; NADPH-dependent methylglyoxal reductase [EC:1.1.1.283]
K03085 SIC1; substrate and inhibitor of the cyclin-dependent protein kinase CDC28
K06651 CLB5_6; S-phase entry cyclin 5/6
K02515 HSL1; serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]
K02516 PRMT5, HSL7; type II protein arginine methyltransferase [EC:2.1.1.320]
K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
K06009 YPS1_2; yapsin 1/2 [EC:3.4.23.41]
K06630 YWHAE; 14-3-3 protein epsilon
K19816 MSS11; transcription activator MSS11
K09448 TEAD; transcriptional enhancer factor
K19851 FLO11; flocculation protein FLO11
|
04012 ErbB signaling pathway [PATH:ko04012]
|
04014 Ras signaling pathway [PATH:ko04014]
|
04015 Rap1 signaling pathway [PATH:ko04015]
|
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07831 MRAS; Ras-related protein M-Ras
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K17697 DOCK4; dedicator of cytokinesis protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04270 P2RY1; P2Y purinoceptor 1
K04172 FPR1; formyl peptide receptor 1
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04266 ADORA2A, ADOR; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04438 CRK, CRKII; C-crk adapter molecule crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K06112 MAGI3; membrane-associated guanylate kinase-related
K08018 RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
K08020 RAPGEF6, PDZGEF2; Rap guanine nucleotide exchange factor 6
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07362 LAT; linker for activation of T cells family member 1
K17698 FYB, ADAP; FYN binding protein
K07361 LCP2; lymphocyte cytosolic protein 2
K17699 SKAP1, SKAP55; src kinase associated phosphoprotein 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K04145 DRD2; dopamine receptor D2
K04277 CNR1; cannabinoid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K17700 RAP1GAP, RAPGAP; RAP1 GTPase activating protein 1
K17701 SIPA1L1, E6TP1; signal-induced proliferation-associated 1 like protein 1
K08013 SIPA1; signal-induced proliferation-associated gene 1
K17702 SIPA1L2, SPAL2; signal-induced proliferation-associated 1 like protein 2
K17703 SIPA1L3, SPAL3; signal-induced proliferation-associated 1 like protein 3
K04680 ID1; DNA-binding protein inhibitor ID1
K16857 THBS1; thrombospondin 1
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K17704 APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
K06271 TLN; talin
K06476 ITGA2B, CD41; integrin alpha 2B
K06493 ITGB3, CD61; integrin beta 3
K05759 PFN; profilin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05746 ENAH, MENA; enabled
K23487 EVL; Ena/VASP-like protein
K05692 ACTB_G1; actin beta/gamma 1
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06082 FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2
K04393 CDC42; cell division control protein 42
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K05702 AF6, MLLT4; afadin
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K17705 KRIT1, CCM1; Krev interaction trapped protein 1
K17706 RGS14; regulator of G-protein signaling 14
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K05718 ITGAL, CD11a; integrin alpha L
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K05719 ITGB1, CD29; integrin beta 1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
|
04310 Wnt signaling pathway [PATH:ko04310]
|
04330 Notch signaling pathway [PATH:ko04330]
|
04340 Hedgehog signaling pathway [PATH:ko04340]
|
04341 Hedgehog signaling pathway - fly [PATH:ko04341]
|
04350 TGF-beta signaling pathway [PATH:ko04350]
|
04390 Hippo signaling pathway [PATH:ko04390]
|
04391 Hippo signaling pathway - fly [PATH:ko04391]
|
04392 Hippo signaling pathway - multiple species [PATH:ko04392]
|
04370 VEGF signaling pathway [PATH:ko04370]
|
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K08273 SH2D2A, VRAP; SH2 domain-containing protein 2A
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K17447 SHC2; SHC-transforming protein 2
K05760 PXN; paxillin
K04393 CDC42; cell division control protein 42
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04455 HSPB1; heat shock protein beta-1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
|
04371 Apelin signaling pathway [PATH:ko04371]
|
04630 JAK-STAT signaling pathway [PATH:ko04630]
|
04064 NF-kappa B signaling pathway [PATH:ko04064]
|
04668 TNF signaling pathway [PATH:ko04668]
|
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K09558 BAG4; BCL2-associated athanogene 4
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K05632 ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K06052 JAG1, CD339; jagged-1
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05433 IL15; interleukin 15
K05419 LIF; leukemia inhibitory factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K09258 BCL3; B-cell CLL/lymphoma 3 protein
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K03172 TRAF1; TNF receptor-associated factor 1
K17072 IFI47; interferon gamma inducible protein 47
K09028 JUNB; transcription factor jun-B
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K16366 EDN1; endothelin-1
K05449 VEGFC_D; vascular endothelial growth factor C/D
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03174 TRAF3; TNF receptor-associated factor 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K19901 DAB2IP, AIP1; disabled homolog 2-interacting protein
K09444 IRF1; interferon regulatory factor 1
K05415 IFNB; interferon beta
|
04066 HIF-1 signaling pathway [PATH:ko04066]
|
04068 FoxO signaling pathway [PATH:ko04068]
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4, MST1; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10, CSIF; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K06623 CDKN2D, P19, INK4D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R, CD127; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
K04293 S1PR4, EDG6; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
|
04020 Calcium signaling pathway [PATH:ko04020]
|
04070 Phosphatidylinositol signaling system [PATH:ko04070]
|
04072 Phospholipase D signaling pathway [PATH:ko04072]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K26384 SPTSS; serine palmitoyltransferase small subunit
K04710 CERS1, LASS1; sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K24621 CERS2_4, LASS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24622 CERS3, LASS3; very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K23727 CERS5_6, LASS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K12350 SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K18953 NSMAF, FAN; factor associated with neutral sphingomyelinase activation
K12351 SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K12349 ASAH2; neutral ceramidase [EC:3.5.1.23]
K01441 ACER1_2, ASAH3; alkaline ceramidase [EC:3.5.1.23]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04451 TP53, P53; tumor protein p53
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K03898 KNG, BK; kininogen
K04265 ADORA1; adenosine receptor A1
K04268 ADORA3; adenosine receptor A3
K03916 BDKRB2; bradykinin receptor B2
K04213 OPRD1; delta-type opioid receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04716 SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
K04717 SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K01634 SGPL1, DPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
K04288 S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
K04292 S1PR2, EDG5; sphingosine 1-phosphate receptor 2
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04290 S1PR3, EDG3; sphingosine 1-phosphate receptor 3
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04293 S1PR4, EDG6; sphingosine 1-phosphate receptor 4
K04295 S1PR5, EDG8; sphingosine 1-phosphate receptor 5
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
|
04024 cAMP signaling pathway [PATH:ko04024]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
04144 Endocytosis [PATH:ko04144]
|
04145 Phagosome [PATH:ko04145]
|
04142 Lysosome [PATH:ko04142]
|
04146 Peroxisome [PATH:ko04146]
|
04140 Autophagy - animal [PATH:ko04140]
|
04138 Autophagy - yeast [PATH:ko04138]
|
04136 Autophagy - other [PATH:ko04136]
|
04137 Mitophagy - animal [PATH:ko04137]
|
04139 Mitophagy - yeast [PATH:ko04139]
|
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
K11644 SIN3A; paired amphipathic helix protein Sin3a
K09243 UME6; transcriptional regulatory protein UME6
K17984 ATG32; autophagy-related protein 32
K08955 YME1; ATP-dependent metalloprotease [EC:3.4.24.-]
K11244 WSC; cell wall integrity and stress response component
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K11229 BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K08294 MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K11231 SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
K11233 SSK1; osomolarity two-component system, response regulator SSK1
K11227 PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K17969 FIS1, TTC11, MDV2; mitochondrial fission 1 protein
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K08330 ATG11; autophagy-related protein 11
K17775 MDM34, MMM2; mitochondrial distribution and morphology protein 34
K17774 MDM10; mitochondrial distribution and morphology protein 10
K17765 MDM12; mitochondrial distribution and morphology protein 12
K17764 MMM1; maintenance of mitochondrial morphology protein 1
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19717 ATG33; autophagy-related protein 33
K19708 PTC6, AUP1; protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K18191 FMC1; ATP synthase assembly factor FMC1, mitochondrial
K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
K17800 LETM1, MDM38; LETM1 and EF-hand domain-containing protein 1, mitochondrial
K11841 USP10, UBP3; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
K19718 BRE5; UBP3-associated protein BRE5
|
04148 Efferocytosis [PATH:ko04148]
|
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K03443 PANX1; pannexin 1
K04269 P2RY2; P2Y purinoceptor 2
K04272 P2RY6; P2Y purinoceptor 6
K04298 P2RY12; P2Y purinoceptor 12
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04288 S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
K16343 PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
K05641 ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
K08426 GPR132, G2A; G protein-coupled receptor 132
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K06704 ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K04192 CX3CR1; CX3C chemokine receptor 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K05437 EPO; erythropoietin
K05079 EPOR; erythropoietin receptor
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K17253 MFGE8; lactadherin
K05464 GAS6; growth arrest-specific 6
K05117 MERTK, MER; c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]
K06259 CD36; CD36 antigen
K16857 THBS1; thrombospondin 1
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04259 PTGER2; prostaglandin E receptor 2
K04261 PTGER4; prostaglandin E receptor 4
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K13375 TGFB1; transforming growth factor beta-1
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K00460 ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K19500 ANO6, TMEM16F; anoctamin-6
K19498 ANO3, TMEM16C; anoctamin-3
K19499 ANO4, TMEM16D; anoctamin-4
K19480 ANO5, GDD1, TMEM16E; anoctamin-5
K19501 ANO7, NGEP, TMEM16G; anoctamin-7
K19503 ANO9, TMEM16J; anoctamin-9
K06535 BSG, CD147; basigin
K26813 XKR8; XK-related protein 8
K26814 XKR9; XK-related protein 9
K26811 XKR4_6_7; XK-related protein 4/6/7
K14802 DRS2, ATP8A; phospholipid-transporting ATPase [EC:7.6.2.1]
K26934 ATP11; phospholipid-transporting ATPase [EC:7.6.2.1]
K26935 TMEM30A, CDC50A; cell cycle control protein 50A
K03908 PROS1; protein S
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K06588 ITGB5; integrin beta 5
K05115 AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05116 TYRO3, RSE; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]
K04596 ADGRB1, BAI1; adhesion G protein-coupled receptor B1
K26936 TIMD4, TIM4; T-cell immunoglobulin and mucin domain-containing protein 4
K20413 HAVCR1, CD365; hepatitis A virus cellular receptor 1
K20414 HAVCR2, CD366; hepatitis A virus cellular receptor 2
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K19020 STAB1; stabilin-1
K19013 STAB2, HARE; stabilin-2
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K13708 DOCK1; dedicator of cytokinesis protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06834 ADAM9; disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-]
K08057 CALR; calreticulin
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K04550 LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
K24068 MEGF10_11; multiple epidermal growth factor-like domains protein 10/11
K24318 SCARF1; scavenger receptor class F member 1
K23285 GULP1, CED6; PTB domain-containing engulfment adapter protein 1
K07909 RAB17; Ras-related protein Rab-17
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K20177 VPS3, TGFBRAP1; vacuolar protein sorting-associated protein 3
K20178 VPS8; vacuolar protein sorting-associated protein 8
K20179 VPS11, PEP5; vacuolar protein sorting-associated protein 11
K20180 VPS16; vacuolar protein sorting-associated protein 16
K20181 VPS18, PEP3; vacuolar protein sorting-associated protein 18
K20182 VPS33A; vacuolar protein sorting-associated protein 33A
K07881 RAB14; Ras-related protein Rab-14
K20183 VPS39, VAM6; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
K20184 VPS41; vacuolar protein sorting-associated protein 41
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K23678 PQLC2, SLC66A1, LAAT1; solute carrier family 66 (lysosomal lysine-arginine transporter), member 1
K01476 E3.5.3.1, rocF, arg; arginase [EC:3.5.3.1]
K01581 E4.1.1.17, ODC1, speC, speF; ornithine decarboxylase [EC:4.1.1.17]
K10223 CH25H; cholesterol 25-hydroxylase [EC:1.14.99.38]
K08536 NR1H3, LXRA; liver X receptor alpha
K08535 NR1H2, LXRB; liver X receptor beta
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K05443 IL10, CSIF; interleukin 10
K01052 LIPA; lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13]
K06129 LYPLA3; lysophospholipase III [EC:3.1.1.5]
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K08179 SLC16A1; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 1
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K06266 CD47; CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
K06469 CD24; CD24 antigen
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K06749 SIGLEC10; sialic acid binding Ig-like lectin 10
K06551 SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
|
|
09143 Cell growth and death
|
04110 Cell cycle [PATH:ko04110]
|
04111 Cell cycle - yeast [PATH:ko04111]
|
04112 Cell cycle - Caulobacter [PATH:ko04112]
|
04113 Meiosis - yeast [PATH:ko04113]
|
04114 Oocyte meiosis [PATH:ko04114]
|
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K08556 PGR, NR3C3; progesterone receptor
K08557 AR, NR3C4; androgen receptor
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K02602 CPEB, ORB; cytoplasmic polyadenylation element-binding protein
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K08694 SPDY, RINGO; speedy
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K08836 SLK; STE20-like kinase [EC:2.7.11.1]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K13056 C3H-4; CCCH zinc finger protein C3H-4
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03347 CUL1, CDC53; cullin 1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K10292 FBXO5, EMI1; F-box protein 5
K03348 APC1, ANAPC1; anaphase-promoting complex subunit 1
K03349 APC2, ANAPC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4, ANAPC4; anaphase-promoting complex subunit 4
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7, ANAPC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03357 APC10, ANAPC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11, ANAPC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12456 APC13, ANAPC13; anaphase-promoting complex subunit 13
K25228 APC15, ANAPC15; anaphase-promoting complex subunit 15
K25229 APC16, ANAPC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K10318 FBXO43, EMI2; F-box protein 43
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K13054 REC8L; meiotic recombination protein REC8, animal type
K13055 STAG3; cohesin complex subunit SA-3
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K06626 CCNE; G1/S-specific cyclin-E1
K11580 SGOL1; shugoshin-like 1
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
|
04210 Apoptosis [PATH:ko04210]
|
04214 Apoptosis - fly [PATH:ko04214]
|
04215 Apoptosis - multiple species [PATH:ko04215]
|
04216 Ferroptosis [PATH:ko04216]
|
04217 Necroptosis [PATH:ko04217]
|
04115 p53 signaling pathway [PATH:ko04115]
|
04218 Cellular senescence [PATH:ko04218]
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K24231 KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K21769 MYBL2, B-MYB; myb-related protein B
K21773 LIN9; protein lin-9
K21774 LIN37; protein lin-37
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1, pnt; C-ets-1
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN, NBS1; nibrin
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1, RAD17; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2, ACT1; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04383 IL1A; interleukin 1 alpha
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
|
|
09144 Cellular community - eukaryotes
|
04510 Focal adhesion [PATH:ko04510]
|
04520 Adherens junction [PATH:ko04520]
|
04530 Tight junction [PATH:ko04530]
|
04540 Gap junction [PATH:ko04540]
|
04550 Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]
|
K05419 LIF; leukemia inhibitory factor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K17846 KLF4; krueppel-like factor 4
K16796 SOX2; transcription factor SOX2 (SOX group B)
K04377 MYC; Myc proto-oncogene protein
K04364 GRB2; growth factor receptor-bound protein 2
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K10177 TBX3; T-box protein 3
K10164 NANOG; homeobox protein Nanog
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04666 NODAL; nodal
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04662 BMP4; bone morphogenetic protein 4
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K16790 SMAD5; mothers against decapentaplegic homolog 5
K16791 SMAD9, SMAD8; mothers against decapentaplegic homolog 9
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K17694 ID3; DNA-binding protein inhibitor ID3
K17695 ID4; DNA-binding protein inhibitor ID4
K18498 DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K09063 TCF3, E2A; transcription factor E2-alpha
K08553 NR3B2, ESRRB; estrogen-related receptor beta
K02620 TCF7, TCF-1; transcription factor 7
K09367 POU5F; POU domain transcription factor, class 5
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K09354 HESX1; homeobox protein expressed in ES cells 1
K18487 ZIC3; zinc finger protein ZIC 3
K04668 LEFTY; left-right determination factor
K18499 SKIL; Ski-like protein
K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
K11305 MYST3, KAT6A; histone acetyltransferase MYST3 [EC:2.3.1.48]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K11478 JARID2, JMJ; protein Jumonji
K09222 REST; RE1-silencing transcription factor
K11138 RIF1; telomere-associated protein RIF1
K11487 PCGF1, NSPC1; polycomb group RING finger protein 1
K11460 PCGF2, RNF110; polycomb group RING finger protein 2
K11488 PCGF3; polycomb group RING finger protein 3
K11459 PCGF4, BMI1; polycomb group RING finger protein 4
K11489 PCGF5; polycomb group RING finger protein 5
K11470 PCGF6, MBLR; polycomb group RING finger protein 6
K08031 PAX6; paired box protein 6
K15613 MEIS1; homeobox protein Meis1
K09301 HOX_1; homeobox protein HoxA/B/D1
K18493 LHX5; LIM homeobox protein 5
K09326 OTX1; homeobox protein OTX1
K09081 NEUROG1; neurogenin 1
K09071 HAND1; heart-and neural crest derivatives-expressed protein 1
K18489 DLX5; homeobox protein DLX5
K18484 MYF5; myogenic factor 5
K08026 ONECUT1, HNF6; one cut domain, family member 1 (hepatocyte nuclear factor 6)
K09370 ISL1; insulin gene enhancer protein ISL-1
K09378 ZFHX3, ATBF1; zinc finger homeobox protein 3
K18491 ESX1; homeobox protein ESX1
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
|
04610 Complement and coagulation cascades [PATH:ko04610]
|
04611 Platelet activation [PATH:ko04611]
|
K04264 TBXA2R; thromboxane A2 receptor
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12757 MYL12; myosin regulatory light chain 12
K05215 P2RX1; P2X purinoceptor 1
K16056 ORAI1; calcium release-activated calcium channel protein 1
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K16059 STIM1; stromal interaction molecule 1
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K04270 P2RY1; P2Y purinoceptor 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K17704 APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
K06271 TLN; talin
K06476 ITGA2B, CD41; integrin alpha 2B
K06493 ITGB3, CD61; integrin beta 3
K17084 FERMT3, KIND3; kindlin 3
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K04298 P2RY12; P2Y purinoceptor 12
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04263 PTGIR; prostacyclin receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K04345 PKA; protein kinase A [EC:2.7.11.11]
K06274 VASP; vasodilator-stimulated phosphoprotein
K05692 ACTB_G1; actin beta/gamma 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K06264 GP6; platelet glycoprotein VI
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06481 ITGA2, CD49b; integrin alpha 2
K05719 ITGB1, CD29; integrin beta 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07361 LCP2; lymphocyte cytosolic protein 2
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K03900 VWF; von Willebrand factor
K06260 GP5, CD42d; platelet glycoprotein V
K06261 GP1BA, CD42b; platelet glycoprotein Ib alpha chain
K06262 GP1BB, CD42c; platelet glycoprotein Ib beta chain
K06263 GP9, CD42a; platelet glycoprotein IX
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00509 PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K01832 TBXAS1, CYP5A; thromboxane-A synthase [EC:5.3.99.5]
K08508 SNAP23; synaptosomal-associated protein 23
K08512 VAMP8; vesicle-associated membrane protein 8
|
04613 Neutrophil extracellular trap formation [PATH:ko04613]
|
K06005 SAP; candidapepsin [EC:3.4.23.24]
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06740 SIGLEC9, CD329; sialic acid binding Ig-like lectin 9
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K05404 TLR7; toll-like receptor 7
K10170 TLR8, CD288; toll-like receptor 8
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K05692 ACTB_G1; actin beta/gamma 1
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K24669 PADI4, PAD4; protein-arginine deiminase 4 [EC:3.5.3.15]
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K05718 ITGAL, CD11a; integrin alpha L
K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
K04172 FPR1; formyl peptide receptor 1
K04173 FPRL; formyl peptide receptor-like
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03990 C3; complement component 3
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K03994 C5; complement component 5
K04010 C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
K10802 HMGB1; high mobility group protein B1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K06476 ITGA2B, CD41; integrin alpha 2B
K06493 ITGB3, CD61; integrin beta 3
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K06261 GP1BA, CD42b; platelet glycoprotein Ib alpha chain
K03900 VWF; von Willebrand factor
K06496 SELP, CD62P; selectin, platelet
K06544 SELPLG, CD162; selectin P ligand
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K20917 GSDMD; gasdermin-D
K11303 HAT1, KAT1; histone acetyltransferase 1 [EC:2.3.1.48]
K11251 H2A; histone H2A
K11252 H2B; histone H2B
K11254 H4; histone H4
K11253 H3; histone H3
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
K24665 AZU1; azurocidin
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
K05012 CLCN3_4_5; chloride channel 3/4/5
K09877 AQP9; aquaporin-9
|
04620 Toll-like receptor signaling pathway [PATH:ko04620]
|
K05398 TLR1, CD281; toll-like receptor 1
K10159 TLR2, CD282; toll-like receptor 2
K10169 TLR6, CD286; toll-like receptor 6
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96, MD-2; lymphocyte antigen 96
K05401 TLR3, CD283; toll-like receptor 3
K10160 TLR4, CD284; toll-like receptor 4
K10168 TLR5; toll-like receptor 5
K05404 TLR7; toll-like receptor 7
K10170 TLR8, CD288; toll-like receptor 8
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K10161 TLR9, CD289; toll-like receptor 9
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05402 TOLLIP; toll-interacting protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K10030 IL8, CXCL8; interleukin 8
K12499 CCL5; C-C motif chemokine 5
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K09446 IRF5; interferon regulatory factor 5
K09447 IRF7; interferon regulatory factor 7
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K03174 TRAF3; TNF receptor-associated factor 3
K05411 IRF3; interferon regulatory factor 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K05416 CXCL9; C-X-C motif chemokine 9
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
|
04624 Toll and Imd signaling pathway [PATH:ko04624]
|
K20692 GNBP3; gram-negative bacteria-binding protein 3
K20697 GNBP1; gram-negative bacteria-binding protein 1
K01446 PGRP; peptidoglycan recognition protein
K20674 MODSP; modular serine protease [EC:3.4.21.-]
K20673 GRASS; gram-positive specific serine protease [EC:3.4.21.-]
K20693 SPHINX; sphinx [EC:3.4.21.-]
K20675 SPIRIT; serine protease immune response integrator
K20676 SPHEROIDE; spheroide [EC:3.4.21.-]
K20671 PSH; serine protease persephone [EC:3.4.21.-]
K20698 NEC; necrotic
K20672 SPE; spatzle-processing enzyme [EC:3.4.21.-]
K20694 SPZ; protein spaetzle
K18809 TL; protein toll
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K09254 REL; c-Rel proto-oncogene protein
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K20668 DEF; defensin
K20695 IM1_2_3; immune-induced peptide 1/2/3
K20702 IM4; immune-induced peptide 4
K20670 DRS; drosomycin
K20696 CEC; cecropin
K24097 PGRP-SD; peptidoglycan recognition protein SD
K24076 PGRP-LB; peptidoglycan-recognition protein LB [EC:3.5.1.28]
K24096 PGRP-SB; peptidoglycan recognition protein SB [EC:3.5.1.28]
K24092 PGRP-LA; peptidoglycan recognition protein LA
K24093 PGRP-LD; peptidoglycan recognition protein LD
K24074 PGRP-LE; peptidoglycan recognition protein LE
K24075 PGRP-LC; peptidoglycan recognition protein LC
K24077 PGRP-LF; peptidoglycan-recognition protein LF
K20701 PIRK; poor Imd response upon knock-in
K06689 UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K20699 IMD; immune deficiency
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K13411 DUOX, THOX; dual oxidase [EC:1.6.3.1 1.11.1.-]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K09031 FOSLN; fos-like antigen, invertebrate
K20700 KEY; NF-kappa-B essential modulator
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K09255 ANK2, ANKB; ankyrin-2
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K20703 FAF1; FAS-associated factor 1
K20669 DPT; diptericin
|
04621 NOD-like receptor signaling pathway [PATH:ko04621]
|
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04519 IL1B; interleukin 1 beta
K05482 IL18, IL1F4; interleukin 18
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K10030 IL8, CXCL8; interleukin 8
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
K05230 DEFA; defensin, alpha
K21100 DEFB4; beta-defensin 4
K23126 DEFB103; beta-defensin 103
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K17890 ATG16L1; autophagy-related protein 16-1
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K10435 MAP1LC; microtubule-associated protein 1 light chain
K12795 SUGT1, SGT1; suppressor of G2 allele of SKP1
K20894 SHARPIN; shank-associated RH domain-interacting protein
K10630 RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K12797 CARD6; caspase recruitment domain-containing protein 6
K12792 TRIP6; thyroid receptor-interacting protein 6
K12796 ERBIN, ERBB2IP; erbb2-interacting protein
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12794 CARD9; caspase recruitment domain-containing protein 9
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K12653 NLRX1; NLR family member X1
K08645 lef; anthrax lethal toxin endopeptidase [EC:3.4.24.83]
K11030 pagA; protective antigen
K20909 ANTXR; anthrax toxin receptor
K12798 NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K03443 PANX1; pannexin 1
K05220 P2RX7; P2X purinoceptor 7
K04977 TRPM2; transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04971 TRPV2; transient receptor potential cation channel subfamily V member 2
K04612 CASR; calcium-sensing receptor
K04622 GPRC6A; G protein-coupled receptor family C group 6 member A
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K17820 DHX33; ATP-dependent RNA helicase DHX33 [EC:3.6.4.13]
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K20910 TXNIP; thioredoxin-interacting protein
K03671 TXN, trxA; thioredoxin
K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
K11864 BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K04079 HSP90A, htpG; molecular chaperone HtpG
K12801 CARD8, CARDINAL; caspase recruitment domain-containing protein 8
K15838 GPSM3, AGS4; G-protein signaling modulator 3
K14139 IRGM, LRG47; immunity-related GTPase family M protein [EC:3.6.5.-]
K12802 PYDC1; pyrin domain-containing protein 1
K20911 PYDC2, POP2; pyrin domain-containing protein 2
K12803 MEFV; pyrin
K12804 PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02373 FADD; FAS-associated death domain protein
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K12806 CARD16_17_18; caspase recruitment domain-containing protein 16/17/18
K20863 NLRP6, NALP6; NACHT, LRR and PYD domains-containing protein 6
K20864 NLRP7, NALP7; NACHT, LRR and PYD domains-containing protein 7
K08598 yopJ; YopJ protease family
K20865 NLRP12; NACHT, LRR and PYD domains-containing protein 12
K02406 fliC, hag; flagellin
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K20897 GBP2; guanylate-binding protein 2
K20898 GBP5; guanylate-binding protein 5
K12966 AIM2; absent in melanoma 2
K20914 IFI16; gamma-interferon-inducible protein 16
K20915 TP53BP1, P202; tumor suppressor p53-binding protein 1
K20916 POP3; pyrin domain-only protein 3
K04513 RHOA; Ras homolog gene family, member A
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K06630 YWHAE; 14-3-3 protein epsilon
K20899 GBP1_3_4_7; guanylate-binding protein 1/3/4/7
K04395 CASP5; caspase 5 [EC:3.4.22.58]
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K20917 GSDMD; gasdermin-D
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K10160 TLR4, CD284; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
|
04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
|
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K27391 ZNFX1; NFX1-type zinc finger-containing protein 1
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K12649 DHX58, LGP2; ATP-dependent RNA helicase DHX58 [EC:3.6.4.13]
K03174 TRAF3; TNF receptor-associated factor 3
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K12651 AZI2; 5-azacytidine-induced protein 2
K12652 TBKBP1; TANK-binding kinase 1-binding protein
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10030 IL8, CXCL8; interleukin 8
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K10652 TRIM25, EFP; tripartite motif-containing protein 25 [EC:2.3.2.27]
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
K12159 ISG15; ubiquitin cross-reactive protein
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K12653 NLRX1; NLR family member X1
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K12655 OTUD5, DUBA; OTU domain-containing protein 5 [EC:3.4.19.12]
K12656 SIKE; suppressor of IKK-epsilon
K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
K00863 DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]
|
04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
04625 C-type lectin receptor signaling pathway [PATH:ko04625]
|
K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K14957 LSP1; lymphocyte-specific protein 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K04519 IL1B; interleukin 1 beta
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05429 IL2; interleukin 2
K05443 IL10, CSIF; interleukin 10
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K12794 CARD9; caspase recruitment domain-containing protein 9
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K05426 IL23A; interleukin 23 subunit alpha
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K17514 CLEC6A, DECTIN2; C-type lectin domain family 6 member A
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06563 CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K14958 KSR1; kinase suppressor of Ras 1
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11220 STAT1; signal transducer and activator of transcription 1
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K11221 STAT2; signal transducer and activator of transcription 2
K05492 IL17D, IL27; interleukin 17D
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K09258 BCL3; B-cell CLL/lymphoma 3 protein
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K10059 CLEC4E, MINCLE; C-type lectin domain family 4 member E
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K09444 IRF1; interferon regulatory factor 1
K10058 CLEC4D, MCL, CD368; C-type lectin domain family 4 member D
K10070 CLEC1B; C-type lectin domain family 1 member B
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
04612 Antigen processing and presentation [PATH:ko04612]
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K07366 GRAP2, GADS; GRB2-related adaptor protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K12076 DLG1; disks large protein 1
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K03099 SOS; son of sevenless
K04350 RASGRP1; RAS guanyl-releasing protein 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07367 CARD11; caspase recruitment domain-containing protein 11
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K06470 CD28; CD28 antigen
K06713 ICOS, AILIM, CD278; inducible T-cell co-stimulator
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K04687 IFNG; interferon gamma
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
|
04658 Th1 and Th2 cell differentiation [PATH:ko04658]
|
K06051 DLL; delta
K20995 NOTCH3; Notch 3
K06061 MAML; mastermind
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11222 STAT4; signal transducer and activator of transcription 4
K10166 TBX21; T-box protein 21
K09279 RUNX3, AML2; runt-related transcription factor 3
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05430 IL4; interleukin 4
K05071 IL4R, CD124; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K09035 CMAF, MAF; transcription factor Maf
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
|
04659 Th17 cell differentiation [PATH:ko04659]
|
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K09445 IRF4; interferon regulatory factor 4
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K05434 IL21; interleukin 21
K05075 IL21R, CD360; interleukin 21 receptor
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K05426 IL23A; interleukin 23 subunit alpha
K05065 IL23R; interleukin 23 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K08534 NR1F3, RORC; RAR-related orphan receptor gamma
K08532 NR1F1, RORA; RAR-related orphan receptor alpha
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04079 HSP90A, htpG; molecular chaperone HtpG
K09093 AHR; aryl hydrocarbon receptor
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05445 IL22, IL-TIF; interleukin 22
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05430 IL4; interleukin 4
K05071 IL4R, CD124; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K08367 RUNX1, AML1; runt-related transcription factor 1
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K19598 IL27RA; interleukin 27 receptor alpha
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K10166 TBX21; T-box protein 21
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K10163 FOXP3, IPEX; forkhead box P3
K08527 RARA, NR1B1; retinoic acid receptor alpha
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
|
04657 IL-17 signaling pathway [PATH:ko04657]
|
K05493 IL17E, IL25; interleukin 17E
K05164 IL17RA, CD217; interleukin 17 receptor A
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K21124 TRAF3IP2, ACT1; adaptor protein CIKS
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04379 FOS; proto-oncogene protein c-fos
K09029 FOSB; protein FosB
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04502 FOSL1; fos-like antigen 1
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K21083 CCL17; C-C motif chemokine 17
K16597 CCL11; C-C motif chemokine 11
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K03174 TRAF3; TNF receptor-associated factor 3
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K09848 TRAF4; TNF receptor-associated factor 4
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K12890 SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
K13088 ELAVL1, HUR; ELAV-like protein 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K14624 CCL2, MCP1; C-C motif chemokine 2
K05509 CCL7; C-C motif chemokine 7
K14625 CCL20; C-C motif chemokine 20
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K21100 DEFB4; beta-defensin 4
K13908 MUC5; mucin-5
K21126 S100A7; protein S100-A7
K21127 S100A8; protein S100-A8
K21128 S100A9; protein S100-A9
K21129 LCN2; lipocalin 2
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K05491 IL17C, CX2; interleukin 17C
K05168 IL17RE; interleukin 17 receptor E
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K05490 IL17B, CX1; interleukin 17B
K05492 IL17D, IL27; interleukin 17D
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
K06856 IGH; immunoglobulin heavy chain
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05430 IL4; interleukin 4
K05435 IL13; interleukin 13
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K07362 LAT; linker for activation of T cells family member 1
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K20735 ALOX5AP, FLAP; arachidonate 5-lipoxygenase-activating protein
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
K06785 JAM3; junctional adhesion molecule 3
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K06735 JAM2, CD322; junctional adhesion molecule 2
K06483 ITGA4, CD49d; integrin alpha 4
K05719 ITGB1, CD29; integrin beta 1
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K06520 CD99, MIC2; CD99 antigen
K05718 ITGAL, CD11a; integrin alpha L
K06089 F11R, JAM1, CD321; junctional adhesion molecule 1
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K06087 CLDN; claudin
K06088 OCLN; occludin
K06787 ESAM; endothelial cell adhesion molecule
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K08007 EZR, VIL2; ezrin
K05763 MSN; moesin
K05692 ACTB_G1; actin beta/gamma 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K02105 CTNNB1; catenin beta 1
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K05691 CTNNA; catenin alpha
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K06514 THY1, CD90; Thy-1 cell surface antigen
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K05702 AF6, MLLT4; afadin
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K08013 SIPA1; signal-induced proliferation-associated gene 1
K06274 VASP; vasodilator-stimulated phosphoprotein
K05699 ACTN1_4; actinin alpha 1/4
K05700 VCL; vinculin
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K08016 TXK, RLK; tyrosine-protein kinase TXK [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04393 CDC42; cell division control protein 42
K07873 RHOH, TTF; Ras homolog gene family, member H
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
|
09152 Endocrine system
|
04911 Insulin secretion [PATH:ko04911]
|
04910 Insulin signaling pathway [PATH:ko04910]
|
04922 Glucagon signaling pathway [PATH:ko04922]
|
04923 Regulation of lipolysis in adipocytes [PATH:ko04923]
|
04920 Adipocytokine signaling pathway [PATH:ko04920]
|
03320 PPAR signaling pathway [PATH:ko03320]
|
04929 GnRH secretion [PATH:ko04929]
|
04912 GnRH signaling pathway [PATH:ko04912]
|
K05252 GNRH; gonadotropin-releasing hormone
K04280 GNRHR; gonadotropin-releasing hormone receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04393 CDC42; cell division control protein 42
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K08521 LHB; lutropin subunit beta
K08522 CGA; glycoprotein hormones alpha chain
K05250 FSHB; follitropin subunit beta
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K09203 EGR1; early growth response protein 1
|
04913 Ovarian steroidogenesis [PATH:ko04913]
|
04915 Estrogen signaling pathway [PATH:ko04915]
|
04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
|
K08556 PGR, NR3C3; progesterone receptor
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K02602 CPEB, ORB; cytoplasmic polyadenylation element-binding protein
K08694 SPDY, RINGO; speedy
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K06627 CCNA; cyclin-A
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04079 HSP90A, htpG; molecular chaperone HtpG
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K08837 STK10, LOK; serine/threonine kinase 10 [EC:2.7.11.1]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K07827 KRAS, KRAS2; GTPase KRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1, FZR1; cell division cycle 20-like protein 1, cofactor of APC complex
K03348 APC1, ANAPC1; anaphase-promoting complex subunit 1
K03349 APC2, ANAPC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4, ANAPC4; anaphase-promoting complex subunit 4
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7, ANAPC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03357 APC10, ANAPC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11, ANAPC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12456 APC13, ANAPC13; anaphase-promoting complex subunit 13
K25228 APC15, ANAPC15; anaphase-promoting complex subunit 15
K25229 APC16, ANAPC16; anaphase-promoting complex subunit 16
K10403 KIF22; kinesin family member 22
|
04917 Prolactin signaling pathway [PATH:ko04917]
|
K05439 PRL; prolactin
K05081 PRLR; prolactin receptor
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K00965 galT, GALT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04503 CCND1; G1/S-specific cyclin-D1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04701 CISH; cytokine inducible SH2-containing protein
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K04698 SOCS5; suppressor of cytokine signaling 5
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K11220 STAT1; signal transducer and activator of transcription 1
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K17106 WAP; whey acidic protein
K17101 ELF5; E74-like factor 5
K17107 CSN2; beta-casein
K08522 CGA; glycoprotein hormones alpha chain
K08521 LHB; lutropin subunit beta
K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09444 IRF1; interferon regulatory factor 1
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K07593 SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K10151 CCND2; G1/S-specific cyclin-D2
K04526 INS; insulin
|
04921 Oxytocin signaling pathway [PATH:ko04921]
|
04926 Relaxin signaling pathway [PATH:ko04926]
|
K21998 RLN1_2; relaxin 1/2
K04306 RXFP1, LGR7; relaxin family peptide receptor 1
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K16366 EDN1; endothelin-1
K04198 EDNRB; endothelin receptor type B
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K12313 ACTA2; actin, aortic smooth muscle
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K21999 INSL3; insulin-like 3
K04307 RXFP2, LGR8; relaxin family peptide receptor 2
K22000 RLN3; relaxin 3
K08397 RXFP3, RLN3R1; relaxin family peptide receptor 3
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K03099 SOS; son of sevenless
K04439 ARRB; beta-arrestin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K22001 INSL5; insulin-like 5
K08398 RXFP4, RLN3R2; relaxin family peptide receptor 4
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
|
04935 Growth hormone synthesis, secretion and action [PATH:ko04935]
|
K05260 GHRH; growth hormone-releasing hormone
K04584 GHRHR; growth hormone releasing hormone receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K05237 SST; somatostatin
K04217 SSTR1; somatostatin receptor 1
K04218 SSTR2; somatostatin receptor 2
K04219 SSTR3; somatostatin receptor 3
K04221 SSTR5; somatostatin receptor 5
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K09363 POU1F, PIT1; POU domain transcription factor, class 1
K04379 FOS; proto-oncogene protein c-fos
K05438 GH; growth hormone
K05254 GHRL; ghrelin
K04284 GHSR; growth hormone secretagogue receptor
K25968 MRAP2; melanocortin-2 receptor accessory protein 2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K05080 GHR; growth hormone receptor
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K11220 STAT1; signal transducer and activator of transcription 1
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05459 IGF1; insulin-like growth factor 1
K09028 JUNB; transcription factor jun-B
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K17256 IGFALS, ALS; insulin-like growth factor-binding protein complex acid labile subunit
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
|
04918 Thyroid hormone synthesis [PATH:ko04918]
|
04919 Thyroid hormone signaling pathway [PATH:ko04919]
|
04928 Parathyroid hormone synthesis, secretion and action [PATH:ko04928]
|
04916 Melanogenesis [PATH:ko04916]
|
04924 Renin secretion [PATH:ko04924]
|
04614 Renin-angiotensin system [PATH:ko04614]
|
04925 Aldosterone synthesis and secretion [PATH:ko04925]
|
04927 Cortisol synthesis and secretion [PATH:ko04927]
|
|
09153 Circulatory system
|
04260 Cardiac muscle contraction [PATH:ko04260]
|
04261 Adrenergic signaling in cardiomyocytes [PATH:ko04261]
|
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K21108 BVES, POPDC1; blood vessel epicardial substance
K26206 POPDC2; popeye domain-containing protein 2
K26207 POPDC3; popeye domain-containing protein 3
K04913 KCNK2, K2P2.1; potassium channel subfamily K member 2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K04926 KCNQ1, KV7.1; potassium voltage-gated channel KQT-like subfamily member 1
K04894 KCNE1; potassium voltage-gated channel Isk-related subfamily E member 1
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K04838 SCN5A, NAV1.5; voltage-gated sodium channel type V alpha
K04839 SCN7A, SCN6A; voltage-gated sodium channel type VII alpha
K04845 SCN1B; voltage-gated sodium channel type I beta
K04848 SCN4B; voltage-gated sodium channel type IV beta
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04962 RYR2; ryanodine receptor 2
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K05865 TNNC1; troponin C, slow skeletal and cardiac muscles
K12044 TNNI3; troponin I, cardiac muscle
K12045 TNNT2; troponin T, cardiac muscle
K10373 TPM1; tropomyosin 1
K10374 TPM2; tropomyosin 2
K09290 TPM3; tropomyosin 3
K10375 TPM4; tropomyosin 4
K12314 ACTC1; actin, alpha cardiac muscle
K17751 MYH6_7; myosin heavy chain 6/7
K10351 MYL2; myosin regulatory light chain 2
K12749 MYL3; myosin light chain 3
K12750 MYL4; myosin light chain 4
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K09821 AGT, SERPINA8; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K04167 AGTR2; angiotensin II receptor type 2
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K08050 PPP1R1A; protein phosphatase 1 regulatory subunit 1A
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K09052 CREM; cAMP response element modulator
K02161 BCL2; apoptosis regulator Bcl-2
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
|
04270 Vascular smooth muscle contraction [PATH:ko04270]
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
04724 Glutamatergic synapse [PATH:ko04724]
|
04727 GABAergic synapse [PATH:ko04727]
|
04725 Cholinergic synapse [PATH:ko04725]
|
04728 Dopaminergic synapse [PATH:ko04728]
|
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K01593 DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K08155 SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K04144 DRD1; dopamine receptor D1
K05840 DRD5; dopamine receptor D5
K15493 CALY; neuron-specific vesicular protein calcyon
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04379 FOS; proto-oncogene protein c-fos
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K15494 PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04833 SCN1A, NAV1.1; voltage-gated sodium channel type I alpha
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04997 KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9, KIR3.3; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
K04146 DRD3; dopamine receptor D3
K04147 DRD4; dopamine receptor D4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04145 DRD2; dopamine receptor D2
K04439 ARRB; beta-arrestin
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K10396 KIF5; kinesin family member 5
K02223 CLOCK, KAT13D; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
K02296 ARNTL, BMAL1, CYC; aryl hydrocarbon receptor nuclear translocator-like protein 1
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K00274 MAO, aofH; monoamine oxidase [EC:1.4.3.4]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
|
04726 Serotonergic synapse [PATH:ko04726]
|
04720 Long-term potentiation [PATH:ko04720]
|
04730 Long-term depression [PATH:ko04730]
|
04723 Retrograde endocannabinoid signaling [PATH:ko04723]
|
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K13985 NAPEPLD; N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [EC:3.1.4.54]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13806 DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.116]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13700 ABHD6; abhydrolase domain-containing protein 6 [EC:3.1.1.23]
K15528 FAAH; fatty acid amide hydrolase [EC:3.5.1.99]
K04277 CNR1; cannabinoid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04997 KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9, KIR3.3; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K15015 SLC32A, VGAT; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K15291 RIMS1, RIM1; regulating synaptic membrane exocytosis protein 1
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05186 GABRG; gamma-aminobutyric acid receptor subunit gamma
K05184 GABRD; gamma-aminobutyric acid receptor subunit delta
K05185 GABRE; gamma-aminobutyric acid receptor subunit epsilon
K05192 GABRQ; gamma-aminobutyric acid receptor subunit theta
K05189 GABRP; gamma-aminobutyric acid receptor subunit pi
K05190 GABRR; gamma-aminobutyric acid receptor subunit rho
|
04721 Synaptic vesicle cycle [PATH:ko04721]
|
04722 Neurotrophin signaling pathway [PATH:ko04722]
|
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K12457 NTF4; neurotrophin 4
K04356 NTF3; neurotrophin 3
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K07193 SH2B, APS; SH2B adapter protein 2
K12459 SH2B1_3; SH2B adaptor protein 1/3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K02161 BCL2; apoptosis regulator Bcl-2
K12460 KIDINS220, ARMS; ankyrin repeat-rich membrane spanning protein
K12461 FRS2; fibroblast growth factor receptor substrate 2
K04438 CRK, CRKII; C-crk adapter molecule crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K09593 GAB1; GRB2-associated-binding protein 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K09408 FOXO3; forkhead box protein O3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K12462 ARHGDI, RHOGDI; Rho GDP-dissociation inhibitor
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04451 TP53, P53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K10148 TP73; tumor protein p73
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12458 ZNF274; zinc finger protein 274
K12463 PRDM4; PR domain zinc finger protein 4 [EC:2.1.1.-]
K12464 MAGED1, NRAGE; melanoma-associated antigen D1
K12465 NGFRAP1; nerve growth factor receptor-associated protein 1
K06630 YWHAE; 14-3-3 protein epsilon
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K12388 SORT1; sortilin
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
|
|
09157 Sensory system
|
04744 Phototransduction [PATH:ko04744]
|
04745 Phototransduction - fly [PATH:ko04745]
|
04740 Olfactory transduction [PATH:ko04740]
|
04742 Taste transduction [PATH:ko04742]
|
04750 Inflammatory mediator regulation of TRP channels [PATH:ko04750]
|
K03898 KNG, BK; kininogen
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04149 HRH1; histamine receptor H1
K04269 P2RY2; P2Y purinoceptor 2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
K00458 ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04984 TRPA1, ANKTM1; transient receptor potential cation channel subfamily A member 1
K05222 TRPV1; transient receptor potential cation channel subfamily V member 1
K04829 ASIC1, ACCN2, BNAC2; acid-sensing ion channel 1
K04828 ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
K04830 ASIC3, ACCN3; acid-sensing ion channel 3
K04831 ASIC4, ACCN4, BNAC4; acid-sensing ion channel 4
K04832 ASIC5, ACCN5; acid-sensing ion channel 5
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04983 TRPM8; transient receptor potential cation channel subfamily M member 8
K04259 PTGER2; prostaglandin E receptor 2
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04234 F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K07425 CYP4A; long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K18051 PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K05459 IGF1; insulin-like growth factor 1
K04971 TRPV2; transient receptor potential cation channel subfamily V member 2
K04972 TRPV3; transient receptor potential cation channel subfamily V member 3
|
|
09158 Development and regeneration
|
04320 Dorso-ventral axis formation [PATH:ko04320]
|
04360 Axon guidance [PATH:ko04360]
|
04361 Axon regeneration [PATH:ko04361]
|
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K20105 CED-4; cell death protein 4
K20106 CED-3; cell death protein 3
K10693 MYCBP2, PAM; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K09442 SPDEF; SAM pointed domain-containing ETS transcription factor
K23479 CCAAT/enhancer binding protein (C/EBP), other
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K12494 PSD; PH and SEC7 domain-containing protein
K10393 KIF2_24, MCAK; kinesin family member 2/24
K23439 AGBL4, CCP6; cytosolic carboxypeptidase protein 6 [EC:3.4.17.24]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K23489 SVH1, Teq; HGF/MSP/plasminogen-like protein
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09031 FOSLN; fos-like antigen, invertebrate
K15528 FAAH; fatty acid amide hydrolase [EC:3.5.1.99]
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K00901 dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K01593 DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09408 FOXO3; forkhead box protein O3
K16336 SDC2, CD362; syndecan 2
K06704 ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K02599 NOTCH1; Notch 1
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K06839 SLIT2; slit 2
K05110 EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
K06754 ROBO2; roundabout, axon guidance receptor 2
K06843 NTN1; netrin 1
K23487 EVL; Ena/VASP-like protein
K23488 RAPH1; Ras-associated and pleckstrin homology domains-containing protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16980 MIRLET7; microRNA let-7
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K11593 ELF2C, AGO; eukaryotic translation initiation factor 2C
K23480 ZNF362_384, LIN-29; zinc finger protein 362/384
|
04380 Osteoclast differentiation [PATH:ko04380]
|
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05148 TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K05415 IFNB; interferon beta
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K09029 FOSB; protein FosB
K09030 FOSL2; fos-like antigen 2
K04502 FOSL1; fos-like antigen 1
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K09028 JUNB; transcription factor jun-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K08008 NOX1, MOX1; NADPH oxidase 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K14377 OSCAR; osteoclast-associated immunoglobulin-like receptor
K06512 LILR, CD85; leukocyte immunoglobulin-like receptor
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K14378 TREM2; triggering receptor expressed on myeloid cells 2
K06551 SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
K07992 TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K07361 LCP2; lymphocyte cytosolic protein 2
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K26770 TMEM64; transmembrane protein 64
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09438 SPI1; transcription factor PU.1
K09455 MITF; microphthalmia-associated transcription factor
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K14379 ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
K04576 CALCR; calcitonin receptor
K06493 ITGB3, CD61; integrin beta 3
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K08091 GAB2; GRB2-associated-binding protein 2
K14380 FHL2; four and a half LIM domains protein 2
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K14381 SQSTM1; sequestosome 1
|
|
09149 Aging
|
04211 Longevity regulating pathway [PATH:ko04211]
|
04212 Longevity regulating pathway - worm [PATH:ko04212]
|
K19763 JKK1; dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K19764 INS7; insulin-like neuropeptide
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K27390 HCFC2; host cell factor 2
K17491 SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
K14739 MT1_2; metallothionein 1/2
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K19765 HSBP1; heat shock factor-binding protein 1
K18463 CCDC53; WASH complex subunit CCDC53
K18461 WASH1; WAS protein family homolog 1
K09414 HSF1; heat shock transcription factor 1
K19766 HSP16.1; heat shock protein Hsp-16.1/Hsp-16.11
K19767 HSP16.49; heat shock protein Hsp-16.48/Hsp-16.49
K19768 HSP12.6; heat shock protein 12.6
K19769 SIP1; stress-induced protein 1
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K11204 GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K08035 FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K19770 RNASEK; ribonuclease kappa [EC:3.1.-.-]
K12824 TCERG1, CA150; transcription elongation regulator 1
K17705 KRIT1, CCM1; Krev interaction trapped protein 1
K19771 LIPL4; lipase
K19772 LIPS17; triacylglycerol lipase
K14938 NVD, DAF36; cholesterol 7-desaturase [EC:1.14.19.21]
K22878 DAF9; cytochrome P450 daf-9 [EC:1.14.15.15]
K14035 NR1IN; nuclear receptor subfamily 1 group I
K13356 FAR; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
K19773 NHR80; nuclear hormone receptor family member NHR-80
K00507 SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K01358 clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
K19762 HAF1; ATP-binding cassette, subfamily B, HAIF transporter
K19774 DVE1; homeobox domain-containing protein
K13113 UBL5, HUB1; ubiquitin-like protein 5
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
K04043 dnaK, HSPA9; molecular chaperone DnaK
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
|
04213 Longevity regulating pathway - multiple species [PATH:ko04213]
|
|
09159 Environmental adaptation
|
04710 Circadian rhythm [PATH:ko04710]
|
04713 Circadian entrainment [PATH:ko04713]
|
04711 Circadian rhythm - fly [PATH:ko04711]
|
04712 Circadian rhythm - plant [PATH:ko04712]
|
04714 Thermogenesis [PATH:ko04714]
|
K04143 ADRB3; adrenergic receptor beta-3
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K22411 ZNF516; zinc finger protein 516
K11450 KDM1A, AOF2, LSD1; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
K08769 UCP1, SLC25A7; solute carrier family 25 (mitochondrial uncoupling protein), member 7
K15601 KDM3; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A, INO80K; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11653 ARID1; AT-rich interactive domain-containing protein 1
K22198 BAF45B_C, DPF1_3; BRG1-associated factor 45B/C
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07202 PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K11416 SIRT6, SIR2L6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
K22429 FGF21; fibroblast growth factor 21
K08768 PLIN1; perilipin-1
K07188 LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
K16816 PNPLA2, ATGL; patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3]
K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K05259 GCG; glucagon
K16622 BMP8; bone morphogenetic protein 8
K04277 CNR1; cannabinoid receptor 1
K12334 NPPA; natriuretic peptide A
K12335 NPPB; natriuretic peptide B
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K22404 KLB; beta-klotho
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K12461 FRS2; fibroblast growth factor receptor substrate 2
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07204 RAPTOR; regulatory associated protein of mTOR
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K01897 ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K18159 NDUFAF1, CIA30; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1
K18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
K09008 NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
K18161 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
K18163 NDUFAF6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6
K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
K24726 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02262 COX3; cytochrome c oxidase subunit 3
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02257 COX10, ctaB, cyoE; heme o synthase [EC:2.5.1.141]
K02258 COX11, ctaG; cytochrome c oxidase assembly protein subunit 11
K18181 COX14; cytochrome c oxidase assembly factor 14
K02259 COX15, ctaA; heme a synthase [EC:1.17.99.9]
K18182 COX16; cytochrome c oxidase assembly protein subunit 16
K02260 COX17; cytochrome c oxidase assembly protein subunit 17
K17797 COX18; mitochondrial inner membrane protein COX18
K18183 COX19; cytochrome c oxidase assembly protein subunit 19
K18184 COX20; cytochrome c oxidase assembly protein subunit 20
K18173 COA1; cytochrome c oxidase assembly factor 1
K18175 CCDC56, COA3; cytochrome c oxidase assembly factor 3, animal type
K18177 COA4; cytochrome c oxidase assembly factor 4
K18178 COA5, PET191; cytochrome c oxidase assembly factor 5
K18179 COA6; cytochrome c oxidase assembly factor 6
K18180 COA7, SELRC1, RESA1; cytochrome c oxidase assembly factor 7
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02129 ATPeF0E, ATP5I; F-type H+-transporting ATPase subunit e
K02130 ATPeF0F, ATP5J2; F-type H+-transporting ATPase subunit f
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K02140 ATPeFG, ATP5L, ATP20; F-type H+-transporting ATPase subunit g
K08766 CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K15109 SLC25A20_29, CACT, CACL, CRC1; solute carrier family 25 (mitochondrial carnitine/acylcarnitine transporter), member 20/29
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
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04626 Plant-pathogen interaction [PATH:ko04626]
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:ko05200]
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05202 Transcriptional misregulation in cancer [PATH:ko05202]
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05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
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K06256 CD44; CD44 antigen
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06106 CTTN, EMS1; cortactin
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K04393 CDC42; cell division control protein 42
K04375 ELK1; ETS domain-containing protein Elk-1
K08550 ESR1, NR3A1; estrogen receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K05692 ACTB_G1; actin beta/gamma 1
K04437 FLNA; filamin-A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10380 ANK1; ankyrin-1
K09255 ANK2, ANKB; ankyrin-2
K09259 ANK3, ANKG; ankyrin-3
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K10164 NANOG; homeobox protein Nanog
K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
K03685 rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
K04692 STAT3; signal transducer and activator of transcription 3
K16863 MIR21; microRNA 21
K09069 TWIST; twist
K16864 MIR10A; microRNA 10a
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K04660 DCN; decorin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K06497 CD63, MLA1, TSPAN30; CD63 antigen
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13375 TGFB1; transforming growth factor beta-1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K16865 PDCD4; programmed cell death protein 4
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05425 IL12B; interleukin 12B
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04377 MYC; Myc proto-oncogene protein
K02105 CTNNB1; catenin beta 1
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09108 TFAP4; transcription factor AP-4
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K16866 TIMP3; metalloproteinase inhibitor 3
K16857 THBS1; thrombospondin 1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08122 LUM; lumican
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K13376 TGFB2; transforming growth factor beta-2
K04500 SMAD2; mothers against decapentaplegic homolog 2
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K06257 SDC1, CD138; syndecan 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03985 PLAUR, CD87; plasminogen activator, urokinase receptor
K06236 COL1A; collagen type I alpha
K06481 ITGA2, CD49b; integrin alpha 2
K05719 ITGB1, CD29; integrin beta 1
K06251 VTN; vitronectin
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05717 FN1; fibronectin 1
K06588 ITGB5; integrin beta 5
K05460 HGF; hepatocyte growth factor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K06484 ITGA5, CD49e; integrin alpha 5
K16336 SDC2, CD362; syndecan 2
K08007 EZR, VIL2; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K16338 SDC4; syndecan 4
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K12461 FRS2; fibroblast growth factor receptor substrate 2
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K16867 NUDT16L1, SDOS; NUDT16-like protein 1
K05760 PXN; paxillin
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08107 GPC1; glypican 1
K13769 IGF2; insulin-like growth factor 2
K08109 GPC3; glypican 3
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K11988 SHH; sonic hedgehog
K11989 IHH; indian hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K09543 HSPB2; heat shock protein beta-2
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
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05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
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05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
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05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
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K07755 AS3MT; arsenite methyltransferase [EC:2.1.1.137]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K14700 SLC26A1, SAT1; solute carrier family 26 (sulfate anion transporter), member 1
K14701 SLC26A2, DTD; solute carrier family 26 (sulfate anion transporter), member 2
K14704 SLC26A6; solute carrier family 26 (sulfate anion transporter), member 6
K14706 SLC26A9; solute carrier family 26 (sulfate anion transporter), member 9
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07416 CYP2F; cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K22368 EPHX3; epoxide hydrolase 3 [EC:3.3.2.10]
K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
K00002 AKR1A1, adh; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
K00212 AKR1C1; 20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
K00089 AKR1C2; 3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00037 AKR1C4; 3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K09093 AHR; aryl hydrocarbon receptor
K12550 LPO; lactoperoxidase [EC:1.11.1.7]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08008 NOX1, MOX1; NADPH oxidase 1
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K02158 BAD; Bcl-2-antagonist of cell death
K05696 PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K05698 PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
K14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K05448 VEGFA; vascular endothelial growth factor A
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
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05203 Viral carcinogenesis [PATH:ko05203]
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05230 Central carbon metabolism in cancer [PATH:ko05230]
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05231 Choline metabolism in cancer [PATH:ko05231]
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05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
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K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K04692 STAT3; signal transducer and activator of transcription 3
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10161 TLR9, CD289; toll-like receptor 9
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05842 TRIF; toll-like receptor adapter molecule 1
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K06745 PDL1, CD274; programmed cell death 1 ligand 1
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K09034 BATF; ATF-like basic leucine zipper transcriptional factor
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04350 RASGRP1; RAS guanyl-releasing protein 1
K06470 CD28; CD28 antigen
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
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09162 Cancer: specific types
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09172 Infectious disease: viral
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05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
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05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
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K24266 gp120; HIV envelope glycoprotein gp120
K06454 CD4; T-cell surface glycoprotein CD4
K22890 vpu; HIV-1 protein Vpu
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K22891 nef; HIV protein Nef
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05760 PXN; paxillin
K04438 CRK, CRKII; C-crk adapter molecule crk
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K02158 BAD; Bcl-2-antagonist of cell death
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K19258 tat; HIV protein Tat
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K22892 vif; HIV virion infectivity factor
K22202 vpr; HIV virus protein R
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]
K06731 BST2, CD317; bone marrow stromal cell antigen 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K12392 AP1B1; AP-1 complex subunit beta-1
K12391 AP1G1; AP-1 complex subunit gamma-1
K12393 AP1M; AP-1 complex subunit mu
K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
K12395 AP1S3; AP-1 complex subunit sigma-3
K08055 B2M; beta-2-microglobulin
K03873 ELOB, TCEB2; elongin-B
K03872 ELOC, TCEB1; elongin-C
K10612 CUL5; cullin 5
K10611 RBX2, ROC2, RNF7; RING-box protein 2
K11789 DCAF1, VPRBP; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
K10610 DDB1; DNA damage-binding protein 1
K10609 CUL4; cullin 4
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
|
05161 Hepatitis B [PATH:ko05161]
|
K23128 S; Orthohepadnavirus large envelope protein
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K14341 SLC10A1, NTCP; solute carrier family 10 (sodium/bile acid cotransporter), member 1
K21854 X; Orthohepadnavirus protein X
K23129 C; Orthohepadnavirus capsid protein
K21037 P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H [EC:2.7.7.7 2.7.7.49 3.1.26.4]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K02161 BCL2; apoptosis regulator Bcl-2
K02158 BAD; Bcl-2-antagonist of cell death
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04451 TP53, P53; tumor protein p53
K06627 CCNA; cyclin-A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K15041 VDAC3; voltage-dependent anion channel protein 3
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04448 JUN; transcription factor AP-1
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K10030 IL8, CXCL8; interleukin 8
K04802 PCNA; proliferating cell nuclear antigen
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04375 ELK1; ETS domain-containing protein Elk-1
K10159 TLR2, CD282; toll-like receptor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K10160 TLR4, CD284; toll-like receptor 4
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K05405 IL6; interleukin 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
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05160 Hepatitis C [PATH:ko05160]
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05171 Coronavirus disease - COVID-19 [PATH:ko05171]
|
K25011 nsp1; SARS coronavirus host translation inhibitor nsp1
K25012 nsp2; SARS coronavirus non-structural protein 2
K25013 nsp3; SARS coronavirus non-structural protein 3 [EC:3.4.19.12]
K25014 nsp4; SARS coronavirus non-structural protein 4
K25015 nsp5; SARS coronavirus 3C-like proteinase [EC:3.4.22.69]
K25016 nsp6; SARS coronavirus non-structural protein 6
K25017 nsp7; SARS coronavirus non-structural protein 7
K25018 nsp8; SARS coronavirus non-structural protein 8
K25019 nsp9; SARS coronavirus non-structural protein 9
K25020 nsp10; SARS coronavirus non-structural protein 10
K25021 nsp12; Coronaviridae RNA-directed RNA polymerase [EC:2.7.7.48]
K25022 nsp13; SARS coronavirus helicase [EC:5.6.2.3 3.6.4.13]
K25023 nsp14; SARS coronavirus proofreading exoribonuclease [EC:3.1.13.-]
K25024 nsp15; SARS coronavirus uridylate-specific endoribonuclease
K25025 nsp16; SARS coronavirus 2'-O-methyltransferase [EC:2.1.1.-]
K24152 S; SARS coronavirus spike glycoprotein
K24151 E; SARS coronavirus envelope small membrane protein
K24150 M; SARS coronavirus membrane protein
K24106 N; SARS coronavirus nucleocapsid protein
K24579 3a; SARS coronavirus accessory protein 3a
K24580 6; SARS coronavirus accessory protein 6
K24581 7a; SARS coronavirus accessory protein 7a
K24582 7b; SARS coronavirus accessory protein 7b
K24583 8; SARS coronavirus accessory protein 8
K24584 10; SARS coronavirus accessory protein 10
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09708 ACE2, ACEH; angiotensin-converting enzyme 2 [EC:3.4.17.23]
K06724 NRP1, CD304; neuropilin 1
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
K04303 MAS1; proto-oncogene Mas
K04166 AGTR1; angiotensin II receptor type 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04519 IL1B; interleukin 1 beta
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K14624 CCL2, MCP1; C-C motif chemokine 2
K10030 IL8, CXCL8; interleukin 8
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05429 IL2; interleukin 2
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K02981 RP-S2e, RPS2; small subunit ribosomal protein S2e
K02985 RP-S3e, RPS3; small subunit ribosomal protein S3e
K02984 RP-S3Ae, RPS3A; small subunit ribosomal protein S3Ae
K02987 RP-S4e, RPS4; small subunit ribosomal protein S4e
K02989 RP-S5e, RPS5; small subunit ribosomal protein S5e
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K02993 RP-S7e, RPS7; small subunit ribosomal protein S7e
K02995 RP-S8e, RPS8; small subunit ribosomal protein S8e
K02997 RP-S9e, RPS9; small subunit ribosomal protein S9e
K02947 RP-S10e, RPS10; small subunit ribosomal protein S10e
K02949 RP-S11e, RPS11; small subunit ribosomal protein S11e
K02951 RP-S12e, RPS12; small subunit ribosomal protein S12e
K02953 RP-S13e, RPS13; small subunit ribosomal protein S13e
K02955 RP-S14e, RPS14; small subunit ribosomal protein S14e
K02958 RP-S15e, RPS15; small subunit ribosomal protein S15e
K02957 RP-S15Ae, RPS15A; small subunit ribosomal protein S15Ae
K02960 RP-S16e, RPS16; small subunit ribosomal protein S16e
K02962 RP-S17e, RPS17; small subunit ribosomal protein S17e
K02964 RP-S18e, RPS18; small subunit ribosomal protein S18e
K02966 RP-S19e, RPS19; small subunit ribosomal protein S19e
K02969 RP-S20e, RPS20; small subunit ribosomal protein S20e
K02971 RP-S21e, RPS21; small subunit ribosomal protein S21e
K02973 RP-S23e, RPS23; small subunit ribosomal protein S23e
K02974 RP-S24e, RPS24; small subunit ribosomal protein S24e
K02975 RP-S25e, RPS25; small subunit ribosomal protein S25e
K02976 RP-S26e, RPS26; small subunit ribosomal protein S26e
K02978 RP-S27e, RPS27; small subunit ribosomal protein S27e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K02979 RP-S28e, RPS28; small subunit ribosomal protein S28e
K02980 RP-S29e, RPS29; small subunit ribosomal protein S29e
K02983 RP-S30e, RPS30; small subunit ribosomal protein S30e
K02998 RP-SAe, RPSA; small subunit ribosomal protein SAe
K02925 RP-L3e, RPL3; large subunit ribosomal protein L3e
K02930 RP-L4e, RPL4; large subunit ribosomal protein L4e
K02932 RP-L5e, RPL5; large subunit ribosomal protein L5e
K02934 RP-L6e, RPL6; large subunit ribosomal protein L6e
K02937 RP-L7e, RPL7; large subunit ribosomal protein L7e
K02936 RP-L7Ae, RPL7A; large subunit ribosomal protein L7Ae
K02938 RP-L8e, RPL8; large subunit ribosomal protein L8e
K02940 RP-L9e, RPL9; large subunit ribosomal protein L9e
K02866 RP-L10e, RPL10; large subunit ribosomal protein L10e
K02865 RP-L10Ae, RPL10A; large subunit ribosomal protein L10Ae
K02868 RP-L11e, RPL11; large subunit ribosomal protein L11e
K02870 RP-L12e, RPL12; large subunit ribosomal protein L12e
K02873 RP-L13e, RPL13; large subunit ribosomal protein L13e
K02872 RP-L13Ae, RPL13A; large subunit ribosomal protein L13Ae
K02875 RP-L14e, RPL14; large subunit ribosomal protein L14e
K02877 RP-L15e, RPL15; large subunit ribosomal protein L15e
K02880 RP-L17e, RPL17; large subunit ribosomal protein L17e
K02883 RP-L18e, RPL18; large subunit ribosomal protein L18e
K02882 RP-L18Ae, RPL18A; large subunit ribosomal protein L18Ae
K02885 RP-L19e, RPL19; large subunit ribosomal protein L19e
K02889 RP-L21e, RPL21; large subunit ribosomal protein L21e
K02891 RP-L22e, RPL22; large subunit ribosomal protein L22e
K02894 RP-L23e, RPL23; large subunit ribosomal protein L23e
K02893 RP-L23Ae, RPL23A; large subunit ribosomal protein L23Ae
K02896 RP-L24e, RPL24; large subunit ribosomal protein L24e
K02898 RP-L26e, RPL26; large subunit ribosomal protein L26e
K02901 RP-L27e, RPL27; large subunit ribosomal protein L27e
K02900 RP-L27Ae, RPL27A; large subunit ribosomal protein L27Ae
K02903 RP-L28e, RPL28; large subunit ribosomal protein L28e
K02905 RP-L29e, RPL29; large subunit ribosomal protein L29e
K02908 RP-L30e, RPL30; large subunit ribosomal protein L30e
K02910 RP-L31e, RPL31; large subunit ribosomal protein L31e
K02912 RP-L32e, RPL32; large subunit ribosomal protein L32e
K02915 RP-L34e, RPL34; large subunit ribosomal protein L34e
K02918 RP-L35e, RPL35; large subunit ribosomal protein L35e
K02917 RP-L35Ae, RPL35A; large subunit ribosomal protein L35Ae
K02920 RP-L36e, RPL36; large subunit ribosomal protein L36e
K02922 RP-L37e, RPL37; large subunit ribosomal protein L37e
K02921 RP-L37Ae, RPL37A; large subunit ribosomal protein L37Ae
K02923 RP-L38e, RPL38; large subunit ribosomal protein L38e
K02924 RP-L39e, RPL39; large subunit ribosomal protein L39e
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02928 RP-L41e, RPL41; large subunit ribosomal protein L41e
K02929 RP-L44e, RPL44; large subunit ribosomal protein L44e
K02941 RP-LP0, RPLP0; large subunit ribosomal protein LP0
K02942 RP-LP1, RPLP1; large subunit ribosomal protein LP1
K02943 RP-LP2, RPLP2; large subunit ribosomal protein LP2
K06856 IGH; immunoglobulin heavy chain
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05404 TLR7; toll-like receptor 7
K10170 TLR8, CD288; toll-like receptor 8
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05401 TLR3, CD283; toll-like receptor 3
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12159 ISG15; ubiquitin cross-reactive protein
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14754 MX; interferon-induced GTP-binding protein Mx
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04010 C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
K03990 C3; complement component 3
K01335 CFB; complement factor B [EC:3.4.21.47]
K01334 CFD; complement factor D [EC:3.4.21.46]
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K06496 SELP, CD62P; selectin, platelet
K03900 VWF; von Willebrand factor
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01330 C1R; complement component 1, r subcomponent [EC:3.4.21.41]
K01331 C1S; complement component 1, s subcomponent [EC:3.4.21.42]
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K03991 MBL; mannose-binding lectin
K03992 MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-]
K03993 MASP2; mannan-binding lectin serine protease 2 [EC:3.4.21.104]
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03917 F13A1; coagulation factor XIII A1 polypeptide [EC:2.3.2.13]
K03906 F13B; coagulation factor XIII B polypeptide
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
|
05164 Influenza A [PATH:ko05164]
|
05162 Measles [PATH:ko05162]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K22774 UL123; HCMV immediate-early protein 1
K22775 UL122; Cytomegalovirus viral transcription factor IE2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K22776 UL38; Cytomegalovirus apoptosis inhibitor UL38
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04684 SP1; transcription factor Sp1
K22777 gH, UL75; Cytomegalovirus envelope glycoprotein H
K22778 gL, UL115; Cytomegalovirus envelope glycoprotein L
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K22779 UL82; Cytomegalovirus tegument protein pp71
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K22780 UL26; Cytomegalovirus tegument protein UL26
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K10030 IL8, CXCL8; interleukin 8
K05405 IL6; interleukin 6
K22781 US28; HCMV envelope protein US28
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K16529 ARHGEF13; A-kinase anchor protein 13
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K02105 CTNNB1; catenin beta 1
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05448 VEGFA; vascular endothelial growth factor A
K22782 UL33; Cytomegalovirus G-protein coupled receptor UL33
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K22783 US27; HCMV envelope glycoprotein US27
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K05760 PXN; paxillin
K21533 vIL10; Herpesviridae/Poxviridae viral interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K21046 UL146; HCMV chemokine vCXCL1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K22784 UL22A; HCMV glycoprotein UL22A
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K22785 US6; HCMV membrane glycoprotein US6
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K21050 US2; HCMV unique short US2 glycoprotein
K22786 US11; HCMV membrane glycoprotein US11
K22787 US3; HCMV membrane glycoprotein US3
K21051 US10; HCMV unique short US10 glycoprotein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K22788 UL36; Cytomegalovirus viral inhibitor of caspase-8-induced apoptosis
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K22789 UL37; UL37 HCMV immediate early glycoprotein
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
K21649 ORF4; KSHV complement control protein
K03990 C3; complement component 3
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K21650 KIE1, ORF50; KSHV transcription activator ORF50
K21859 KIE2, ORF45; KSHV transcription activator ORF45
K21652 vIRF3; KSHV interferon regulatory factor-like protein 3
K05414 IFNA; interferon alpha
K05411 IRF3; interferon regulatory factor 3
K21653 vIRF1, K9; KSHV interferon regulatory factor-like protein 1
K21654 vIRF2, K11; KSHV interferon regulatory factor-like protein 2
K21655 K8; KSHV E3 SUMO-protein ligase K-bZIP
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K21656 K12; KSHV protein K12
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K15308 TTP; tristetraprolin
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K21657 K4; KSHV macrophage inflammatory protein 2
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04176 CCR1, CD191; C-C chemokine receptor type 1
K21658 K4.1; KSHV protein vCCL3
K04179 CCR4, CD194; C-C chemokine receptor type 4
K21659 K6; KSHV protein K6
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K21660 vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K21661 vIAP, K7; KSHV inhibitor of apoptosis protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K21662 vFLIP, K13, ORF71; KSHV FLICE inhibitory protein
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K21651 K15; KSHV signal transducing membrane protein
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K21663 vCyclin, ORF72; KSHV cyclin homolog
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K21664 vLANA, ORF73; KSHV latency-associated nuclear antigen
K06751 MHC1; MHC class I antigen
K21665 MIR1, K3; KSHV E3 ubiquitin-protein ligase MIR1 [EC:2.3.2.36]
K21666 MIR2, K5; KSHV E3 ubiquitin-protein ligase MIR2 [EC:2.3.2.36]
K05132 IFNGR1, CD119; interferon gamma receptor 1
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05413 CD86; CD86 antigen
K07985 MIC; MHC class I-related protein
K10071 CLEC2B; C-type lectin domain family 2 member B
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K08334 BECN, VPS30, ATG6; beclin
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
K10435 MAP1LC; microtubule-associated protein 1 light chain
K21667 vGPCR; KSHV G-protein coupled receptor
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K21860 K14; KSHV OX-2 membrane glycoprotein
K21668 CD200R; cell surface glycoprotein CD200 receptor
K21669 K1; KSHV protein K1
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K10030 IL8, CXCL8; interleukin 8
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K17901 RCAN1, MCIP1; calcipressin-1
K18497 FGF2; fibroblast growth factor 2
K05448 VEGFA; vascular endothelial growth factor A
K17386 PDGFB; platelet-derived growth factor subunit B
K21670 vIL6, K2; KSHV interleukin 6
K05466 ANGPT2; angiopoietin 2
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
K19450 BLLF1; Lymphocryptovirus envelope glycoprotein GP350
K04012 CR2, CD21; complement receptor type 2
K06465 CD19; B-lymphocyte antigen CD19
K19451 gH; Lymphocryptovirus envelope glycoprotein H
K19452 gL; Lymphocryptovirus envelope glycoprotein L
K19453 BBRF2; Lymphocryptovirus virion egress protein UL7
K06752 MHC2; MHC class II antigen
K10159 TLR2, CD282; toll-like receptor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K22972 BPLF1; Lymphocryptovirus large tegment protein deneddylase [EC:3.4.19.12]
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K19455 BGLF4; Lymphocryptovirus serine/threonine-protein kinase BGLF4 [EC:2.7.11.1]
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K19460 LMP2A; Lymphocryptovirus latent membrane protein 2A
K23074 LMP2B; Lymphocryptovirus latent membrane protein 2B
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K19459 LMP1; Lymphocryptovirus latent membrane protein 1
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12159 ISG15; ubiquitin cross-reactive protein
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K19458 EBNA6, EBNA3C; Lymphocryptovirus nuclear antigen 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K22973 BARF1; Lymphocryptovirus secreted protein BARF1
K02161 BCL2; apoptosis regulator Bcl-2
K19463 BHRF1; Lymphocryptovirus apoptosis regulator BHRF1
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K19461 EBNA1, BKRF1; Lymphocryptovirus nuclear antigen 1
K22974 BNLF2A; Lymphocryptovirus protein BNLF2a
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K22975 BILF1; Lymphocryptovirus G-protein coupled receptor BILF1
K19456 EBNALP; Lymphocryptovirus nuclear antigen leader protein
K19457 EBNA2; Lymphocryptovirus nuclear antigen 2
K06063 SNW1, SKIIP, SKIP; SNW domain-containing protein 1
K11644 SIN3A; paired amphipathic helix protein Sin3a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06065 NCOR2, SMRT; nuclear receptor co-repressor 2
K19202 SAP30; histone deacetylase complex subunit SAP30
K06066 CIR; CBF1 interacting corepressor
K21855 EBNA3, EBNA3A; Lymphocryptovirus nuclear antigen 3
K21856 EBNA4, EBNA3B; Lymphocryptovirus nuclear antigen 4
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K06054 HES1; hairy and enhancer of split 1
K06468 FCER2, CD23; low affinity immunoglobulin epsilon Fc receptor
K09279 RUNX3, AML2; runt-related transcription factor 3
K04377 MYC; Myc proto-oncogene protein
K11838 USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K19462 BZLF1; Lymphocryptovirus trans-activator protein BZLF1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K09849 TRAF5; TNF receptor-associated factor 5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01510 ENTPD1_3_8, CD39; apyrase [EC:3.6.1.5]
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K06256 CD44; CD44 antigen
K05718 ITGAL, CD11a; integrin alpha L
K06492 CD58, LFA3; CD58 antigen
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K07606 VIM; vimentin
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K10591 NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
|
05165 Human papillomavirus infection [PATH:ko05165]
|
|
09171 Infectious disease: bacterial
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
K15842 cagA; cytotoxicity-associated immunodominant antigen
K12086 cag1; cag pathogenicity island protein 1
K12087 cag2; cag pathogenicity island protein 2
K12088 cag3; cag pathogenicity island protein 3
K12089 cag4; cag pathogenicity island protein 4
K12090 cag5; cag pathogenicity island protein 5
K03196 virB11, lvhB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
K12091 cag6; cag pathogenicity island protein 6
K12092 cag7; cag pathogenicity island protein 7
K12093 cag8; cag pathogenicity island protein 8
K12094 cag9; cag pathogenicity island protein 9
K12095 cag10; cag pathogenicity island protein 10
K12096 cag11; cag pathogenicity island protein 11
K12097 cag12; cag pathogenicity island protein 12
K12098 cag13; cag pathogenicity island protein 13
K12099 cag14; cag pathogenicity island protein 14
K12100 cag15; cag pathogenicity island protein 15
K12101 cag16; cag pathogenicity island protein 16
K12102 cag17; cag pathogenicity island protein 17
K12103 cag18; cag pathogenicity island protein 18
K12104 cag19; cag pathogenicity island protein 19
K12105 cag20; cag pathogenicity island protein 20
K12106 cag21; cag pathogenicity island protein 21
K12107 cag22; cag pathogenicity island protein 22
K12108 cag23; cag pathogenicity island protein 23 [EC:7.4.2.8]
K12109 cag24; cag pathogenicity island protein 24
K12110 cag25; cag pathogenicity island protein 25
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05701 TJP1, ZO1; tight junction protein 1
K06089 F11R, JAM1, CD321; junctional adhesion molecule 1
K06735 JAM2, CD322; junctional adhesion molecule 2
K06785 JAM3; junctional adhesion molecule 3
K06786 JAM4, JCAM; junctional adhesion molecule 4
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K10030 IL8, CXCL8; interleukin 8
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K06704 ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04393 CDC42; cell division control protein 42
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K12499 CCL5; C-C motif chemokine 5
K11028 vacA; vacuolating cytotoxin
K08114 PTPRZ; receptor-type tyrosine-protein phosphatase zeta [EC:3.1.3.48]
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02153 ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K03191 ureI; acid-activated urea channel
K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5]
K01428 ureC; urease subunit alpha [EC:3.5.1.5]
K08303 prtC, trhP; U32 family peptidase [EC:3.4.-.-]
K15843 hopC, alpA; outer membrane protein HopC/AlpA
K15844 hopB, alpB; outer membrane protein HopB/AlpB
K15845 hopZ; outer membrane protein HopZ
K15846 hpaA; neuraminyllactose-binding hemagglutinin
K15847 babA; outer membrane protein BabA
K15848 sabA; outer membrane protein SabA
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
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K11006 stxA; shiga toxin subunit A
K11007 stxB; shiga toxin subunit B
K06856 IGH; immunoglobulin heavy chain
K23648 espJ; T3SS secreted effector ADP-ribosyltransferase EspJ
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K23649 ABI1; abl interactor 1
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K06083 WASF3; WAS protein family, member 3
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K12785 espG, virA; LEE-encoded effector EspG
K12788 espH; LEE-encoded effector EspH
K10356 MYO1; myosin I
K10357 MYO5; myosin V
K10358 MYO6; myosin VI
K12559 MYO10; myosin X
K10352 MYH9s; myosin heavy chain 9/10/11/14
K23650 espB; LEE-encoded effector EspB
K23651 espT; T3SS secreted effector EspT
K23652 espW; T3SS secreted effector EspW
K12787 map; LEE-encoded effector Map
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K13365 SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
K08007 EZR, VIL2; ezrin
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12809 espG2; T3SS secreted effector EspG-like protein
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K12791 ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
K23653 espM; T3SS effector EspM
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K12790 eae; intimin
K12784 tir; translocated intimin receptor
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K20127 BAIAP2L1, IRTKS; BAI1-associated protein 2-like protein 1
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K12789 tccP; Tir-cytoskeleton coupling protein
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K19475 WIPF; WAS/WASL-interacting protein
K06106 CTTN, EMS1; cortactin
K11294 NCL, NSR1; nucleolin
K05719 ITGB1, CD29; integrin beta 1
K12810 bfpA; major structural subunit of bundle-forming pilus
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K10160 TLR4, CD284; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K10168 TLR5; toll-like receptor 5
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02985 RP-S3e, RPS3; small subunit ribosomal protein S3e
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K23654 nleE, ospZ; T3SS secreted effector NleE
K16042 nleH; non-LEE-encoded effector NleH
K23655 nleC; T3SS secreted effector NleC
K23656 nleD; T3SS secreted effector NleD
K23657 nleB; T3SS secreted effector NleB
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K21889 TMBIM6, BI1, TEGT; Bax inhibitor 1
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K06185 ABCF2; ATP-binding cassette, subfamily F, member 2
K23658 nleF; T3SS secreted effector NleF
K23659 espZ; LEE-encoded effector EspZ
K23660 cif; cell inhibiting factor
K12786 espF; LEE-encoded effector EspF
K03221 yscF, sctF, ssaG, prgI; type III secretion protein F
K22487 prgJ; type III secretion system protein
K23661 escI; type III secretion system protein
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K22265 NLRP4; NACHT, LRR and PYD domains-containing protein 4
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K05482 IL18, IL1F4; interleukin 18
K16041 nleA; non-LEE-encoded effector NleA
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K07874 RAB1A; Ras-related protein Rab-1A
K14007 SEC24; protein transport protein SEC24
K20352 TMED10, ERV25; p24 family protein delta-1
K06088 OCLN; occludin
K06087 CLDN; claudin
K05701 TJP1, ZO1; tight junction protein 1
|
05132 Salmonella infection [PATH:ko05132]
|
K11014 cdtB; cytolethal distending toxin subunit B
K11023 ptxA, artA, pltA; pertussis toxin subunit 1 [EC:2.4.2.-]
K19298 subB, artB, pltB; subtilase cytotoxin, subunit B
K06817 PODXL; podocalyxin-like
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K15347 sifA; secreted effector protein SifA
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K23282 PLEKHM1; pleckstrin homology domain-containing family M member 1
K20179 VPS11, PEP5; vacuolar protein sorting-associated protein 11
K20180 VPS16; vacuolar protein sorting-associated protein 16
K20181 VPS18, PEP3; vacuolar protein sorting-associated protein 18
K20182 VPS33A; vacuolar protein sorting-associated protein 33A
K20183 VPS39, VAM6; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
K20184 VPS41; vacuolar protein sorting-associated protein 41
K23936 sopD2; secreted effector protein SopD2
K13883 RILP; Rab-interacting lysosomal protein
K10413 DYNC1H; dynein cytoplasmic 1 heavy chain
K10414 DYNC2H, DNCH2; dynein cytoplasmic 2 heavy chain
K10415 DYNC1I, DNCI; dynein cytoplasmic 1 intermediate chain
K10416 DYNC1LI, DNCLI; dynein cytoplasmic 1 light intermediate chain
K10417 DYNC2LI; dynein cytoplasmic 2 light intermediate chain
K10418 DYNLL; dynein light chain LC8-type
K10419 DYNLRB, DNCL2; dynein light chain roadblock-type
K10420 DYNLT1_3; dynein light chain Tctex-type 1/3
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1, ARP1; centractin
K16576 ACTR10, ARP11; actin-related protein 10
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K21954 FYCO1; FYVE and coiled-coil domain-containing protein 1
K07955 ARL8; ADP-ribosylation factor-like protein 8
K15348 PLEKHM2, SKIP; pleckstrin homology domain-containing family M member 2
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K15352 pipB2; secreted effector protein PipB2
K15350 sseF; secreted effector protein SseF
K15351 sseG; secreted effector protein SseG
K23935 ACBD3; golgi resident protein GCP60
K04513 RHOA; Ras homolog gene family, member A
K15349 sseJ; secreted effector protein SseJ
K10089 M6PR; cation-dependent mannose-6-phosphate receptor
K07899 RAB9A, RAB9; Ras-related protein Rab-9A
K07900 RAB9B; Ras-related protein Rab-9B
K20282 GCC2; GRIP and coiled-coil domain-containing protein 2
K23937 STX10; syntaxin 10
K15353 sspH2; E3 ubiquitin-protein ligase SspH2
K15354 sseI, srfH; secreted effector protein SseI
K05759 PFN; profilin
K04437 FLNA; filamin-A
K15366 spvB; salmonella plasmid virulence protein B
K07195 EXOC7, EXO70; exocyst complex component 7
K19984 EXOC5, SEC10; exocyst complex component 5
K06111 EXOC4, SEC8; exocyst complex component 4
K17637 EXOC2, SEC5; exocyst complex component 2
K07834 RALA; Ras-related protein Ral-A
K13286 sipC, ipaC, bipC; invasin C
K13284 sipA, ipaA; invasin A
K05692 ACTB_G1; actin beta/gamma 1
K17274 S100A10; protein S100-A10
K17092 ANXA2; annexin A2
K23934 AHNAK; neuroblast differentiation-associated protein AHNAK
K13741 sopE; guanine nucleotide exchange factor SopE
K13740 sptP; secreted effector protein SptP
K07864 RHOJ, TCL; Ras homolog gene family, member J
K13744 ARHGEF26, SGEF; Rho guanine nucleotide exchange factor 26
K07863 RHOG; Ras homolog gene family, member G
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K23938 FHOD1; FH1/FH2 domain-containing protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K23649 ABI1; abl interactor 1
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K06083 WASF3; WAS protein family, member 3
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K10358 MYO6; myosin VI
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K00923 PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K17923 SNX9_18_33; sorting nexin-9/18/33
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K10169 TLR6, CD286; toll-like receptor 6
K10159 TLR2, CD282; toll-like receptor 2
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4, CD284; toll-like receptor 4
K05400 LY96, MD-2; lymphocyte antigen 96
K02406 fliC, hag; flagellin
K10168 TLR5; toll-like receptor 5
K10161 TLR9, CD289; toll-like receptor 9
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K18423 CSE1, CAS, XPO2; exportin-2 (importin alpha re-exporter)
K23940 KPNA1; importin subunit alpha-5
K23583 KPNA3_4; importin subunit alpha-4/3
K02985 RP-S3e, RPS3; small subunit ribosomal protein S3e
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K02105 CTNNB1; catenin beta 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K19557 spvD; salmonella plasmid virulence protein D
K23941 pipA, gogA, gtgA; PipA/GogA/GtgA family effector protease
K15343 sspH1; E3 ubiquitin-protein ligase SspH1
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23942 gogB; Gifsy-1 prophage leucine-rich repeat protein
K10302 FBXO22; F-box protein 22
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K08598 yopJ; YopJ protease family
K18015 elaD, sseL; deubiquitinase [EC:3.4.22.-]
K13450 ospF, mkaD, spvC; phosphothreonine lyase [EC:4.2.3.-]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02161 BCL2; apoptosis regulator Bcl-2
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K07856 RHOB; Ras homolog gene family, member B
K07873 RHOH, TTF; Ras homolog gene family, member H
K07829 RRAS; Ras-related protein R-Ras
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K23943 sseK3; type III secretion system effector arginine glycosyltransferase
K23944 sseK1; type III secretion system effector arginine glycosyltransferase
K23945 sseK2; type III secretion system effector
K23946 slrP; E3 ubiquitin-protein ligase SlrP [EC:2.3.2.27]
K03671 TXN, trxA; thioredoxin
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K22487 prgJ; type III secretion system protein
K03221 yscF, sctF, ssaG, prgI; type III secretion protein F
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18, IL1F4; interleukin 18
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K04395 CASP5; caspase 5 [EC:3.4.22.58]
K20917 GSDMD; gasdermin-D
K13285 sipB, ipaB, bipB; invasin B
|
05131 Shigellosis [PATH:ko05131]
|
K13285 sipB, ipaB, bipB; invasin B
K06256 CD44; CD44 antigen
K13286 sipC, ipaC, bipC; invasin C
K13287 sipD, ipaD, bipD; invasin D
K06484 ITGA5, CD49e; integrin alpha 5
K05719 ITGB1, CD29; integrin beta 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K06106 CTTN, EMS1; cortactin
K05760 PXN; paxillin
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K05699 ACTN1_4; actinin alpha 1/4
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06271 TLN; talin
K05700 VCL; vinculin
K04393 CDC42; cell division control protein 42
K13284 sipA, ipaA; invasin A
K13793 ospE, espO; secreted effector OspE
K13790 icsB, bopA; virulence protein IcsB
K13743 ipgB2; protein IpgB2
K13742 ipgB1; protein IpgB1
K12679 icsA, virG; outer membrane protein IcsA
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05759 PFN; profilin
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04281 CAST; calpastatin
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K08583 CAPNS1, CAPN4; calpain, small subunit 1
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K12785 espG, virA; LEE-encoded effector EspG
K07345 fimA; major type 1 subunit fimbrin (pilin)
K00844 HK; hexokinase [EC:2.7.1.1]
K05862 VDAC1; voltage-dependent anion channel protein 1
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K04519 IL1B; interleukin 1 beta
K05482 IL18, IL1F4; interleukin 18
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10030 IL8, CXCL8; interleukin 8
K23826 TIFA; TRAF-interacting protein with FHA domain-containing protein A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4, CD284; toll-like receptor 4
K02406 fliC, hag; flagellin
K10168 TLR5; toll-like receptor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07368 BCL10; B-cell CLL/lymphoma 10
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K12791 ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K23827 ospI; glutamine deamidase
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K23828 ipaH1.4_2.5; E3 ubiquitin-protein ligase IpaH1.4/2.5 [EC:2.3.2.27]
K10630 RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K20894 SHARPIN; shank-associated RH domain-interacting protein
K23654 nleE, ospZ; T3SS secreted effector NleE
K23829 TNIP1, ABIN1; TNFAIP3-interacting protein 1
K13791 ipaH9.8; invasion plasmid antigen
K13792 ospG; secreted effector OspG
K06689 UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03347 CUL1, CDC53; cullin 1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K23830 ipaH4.5; E3 ubiquitin-protein ligase IpaH4.5 [EC:2.3.2.27]
K23831 ipaH0722; E3 ubiquitin-protein ligase IpaH0722 [EC:2.3.2.27]
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05415 IFNB; interferon beta
K23832 ipaJ; cysteine protease IpaJ [EC:3.4.22.-]
K12836 U2AF1; splicing factor U2AF 35 kDa subunit
K12499 CCL5; C-C motif chemokine 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K11253 H3; histone H3
K11586 CBX3, HP1G; chromobox protein 3
K13450 ospF, mkaD, spvC; phosphothreonine lyase [EC:4.2.3.-]
K08334 BECN, VPS30, ATG6; beclin
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K17890 ATG16L1; autophagy-related protein 16-1
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K10435 MAP1LC; microtubule-associated protein 1 light chain
K03990 C3; complement component 3
K14381 SQSTM1; sequestosome 1
K21348 CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K16942 SEPT2; septin 2
K16938 SEPT3_9_12; septin 3/9/12
K16939 SEPT6_8_11; septin 6/8/11
K16944 SEPT7, CDC3; septin 7
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
K20121 FNBP1; formin-binding protein 1
K13520 icsP, sopA; outer membrane protease [EC:3.4.23.-]
K23833 ospC; secreted effector OspC
K11006 stxA; shiga toxin subunit A
K11007 stxB; shiga toxin subunit B
K11011 set1A; enterotoxin Set1A
K11012 set1B; enterotoxin Set1B
K23345 GLMN; glomulin
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K22487 prgJ; type III secretion system protein
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K03221 yscF, sctF, ssaG, prgI; type III secretion protein F
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K23834 ipaH7.8; E3 ubiquitin-protein ligase IpaH7.8 [EC:2.3.2.27]
|
05135 Yersinia infection [PATH:ko05135]
|
K13735 yeeJ; adhesin/invasin
K12341 yadA; adhesin YadA
K05717 FN1; fibronectin 1
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K05719 ITGB1, CD29; integrin beta 1
K07863 RHOG; Ras homolog gene family, member G
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K06856 IGH; immunoglobulin heavy chain
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K19475 WIPF; WAS/WASL-interacting protein
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05748 WASF2; WAS protein family, member 2
K05760 PXN; paxillin
K12487 GIT2; G protein-coupled receptor kinase interactor 2
K13710 ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K21072 ARHGEF28; A-kinase anchor protein 28
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K17698 FYB, ADAP; FYN binding protein
K23471 SKAP2; src kinase-associated phosphoprotein 2
K23472 ypkA, yopO; serine/threonine protein kinase YpkA [EC:2.7.11.1]
K08599 yopT; YopT peptidase [EC:3.4.22.-]
K23473 yopE; outer membrane virulence protein YopE
K23474 yopH; tyrosine-protein phosphatase YopH [EC:3.1.3.48]
K23475 yopB, popB, aopB; transloator
K23476 yopD, popD, aopD; transloator
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K12803 MEFV; pyrin
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18, IL1F4; interleukin 18
K04519 IL1B; interleukin 1 beta
K23477 yopQ, yopK; protein YopQ
K23478 yopM; outer membrane protein YopM
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05842 TRIF; toll-like receptor adapter molecule 1
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K05415 IFNB; interferon beta
K08598 yopJ; YopJ protease family
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K14624 CCL2, MCP1; C-C motif chemokine 2
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05429 IL2; interleukin 2
K05443 IL10, CSIF; interleukin 10
|
05133 Pertussis [PATH:ko05133]
|
K12681 prn; pertactin
K07345 fimA; major type 1 subunit fimbrin (pilin)
K07347 fimD, fimC, mrkC, htrE, cssD; outer membrane usher protein
K06484 ITGA5, CD49e; integrin alpha 5
K05719 ITGB1, CD29; integrin beta 1
K07326 fhaC; hemolysin activation/secretion protein
K12688 sphB1, nalP, ausP; autotransporter serine protease [EC:3.4.21.-]
K15125 fhaB; filamentous hemagglutinin
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K11004 hlyB, cyaB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
K11003 hlyD, cyaD; membrane fusion protein, hemolysin D
K12340 tolC, bepC, cyaE, raxC, sapF, rsaF, hasF; outer membrane protein
K07389 cyaC, hlyC, rtxC; cytolysin-activating lysine-acyltransferase [EC:2.3.1.-]
K22944 cyaA; bifunctional hemolysin/adenylate cyclase [EC:4.6.1.1]
K02183 CALM; calmodulin
K04513 RHOA; Ras homolog gene family, member A
K05765 CFL; cofilin
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K04519 IL1B; interleukin 1 beta
K12683 brkA; serum resistance protein
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01330 C1R; complement component 1, r subcomponent [EC:3.4.21.41]
K01331 C1S; complement component 1, s subcomponent [EC:3.4.21.42]
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K03990 C3; complement component 3
K03994 C5; complement component 5
K04001 SERPING1, C1INH; C1 inhibitor
K04002 C4BPA; complement component 4 binding protein alpha
K04003 C4BPB; complement component 4 binding protein beta
K12973 pagP, crcA; lipid IVA palmitoyltransferase [EC:2.3.1.251]
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4, CD284; toll-like receptor 4
K04391 CD14; monocyte differentiation antigen CD14
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K05411 IRF3; interferon regulatory factor 3
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23 subunit alpha
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05443 IL10, CSIF; interleukin 10
K09444 IRF1; interferon regulatory factor 1
K10155 IRF8; interferon regulatory factor 8
K10067 SFTPA; pulmonary surfactant-associated protein A
K11023 ptxA, artA, pltA; pertussis toxin subunit 1 [EC:2.4.2.-]
K11024 ptxB; pertussis toxin subunit 2
K11025 ptxC; pertussis toxin subunit 3
K11026 ptxD; pertussis toxin subunit 4
K11027 ptxE; pertussis toxin subunit 5
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K10030 IL8, CXCL8; interleukin 8
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K04383 IL1A; interleukin 1 alpha
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K15126 bteA; type III secretion system cytotoxic effector protein
K07679 evgS, bvgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
K07690 evgA, bvgA; two-component system, NarL family, response regulator EvgA
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02084 APAF1; apoptotic protease-activating factor
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K08061 RFX5; regulatory factor X 5
K08062 RFXANK; regulatory factor X-associated ankyrin-containing protein
K08063 RFXAP; regulatory factor X-associated protein
K08064 NFYA, HAP2; nuclear transcription factor Y, alpha
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K08066 NFYC, HAP5; nuclear transcription factor Y, gamma
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K06752 MHC2; MHC class II antigen
K06505 CD74, DHLAG; CD74 antigen
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K05443 IL10, CSIF; interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K10059 CLEC4E, MINCLE; C-type lectin domain family 4 member E
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K12794 CARD9; caspase recruitment domain-containing protein 9
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07368 BCL10; B-cell CLL/lymphoma 10
K14952 namH; UDP-MurNAc hydroxylase
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K14953 lpqH; ipoprotein LpqH
K14954 lprG; lipoprotein LprG
K14955 lprA; lipoprotein LprA
K02040 pstS; phosphate transport system substrate-binding protein
K04043 dnaK, HSPA9; molecular chaperone DnaK
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
K14956 esx, esat6, cfp10; ESAT-6 family protein
K05399 LBP; lipopolysaccharide-binding protein
K10159 TLR2, CD282; toll-like receptor 2
K05398 TLR1, CD281; toll-like receptor 1
K10169 TLR6, CD286; toll-like receptor 6
K10160 TLR4, CD284; toll-like receptor 4
K04391 CD14; monocyte differentiation antigen CD14
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05482 IL18, IL1F4; interleukin 18
K05426 IL23A; interleukin 23 subunit alpha
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
K10161 TLR9, CD289; toll-like receptor 9
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K06563 CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K14957 LSP1; lymphocyte-specific protein 1
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K14958 KSR1; kinase suppressor of Ras 1
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K07438 CYP27B1; calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]
K08539 VDR, NR1I1; vitamin D3 receptor
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
K03990 C3; complement component 3
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K06462 ITGAX, CD11c; integrin alpha X
K06464 ITGB2, CD18; integrin beta 2
K06461 ITGAM, CD11b; integrin alpha M
K06560 MRC, CD206, CD280; mannose receptor, C type
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02183 CALM; calmodulin
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K12478 EEA1; early endosome antigen 1
K07897 RAB7A; Ras-related protein Rab-7A
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K06528 LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
K21302 sapM; phosphatidylinositol-3-phosphatase [EC:3.1.3.64]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K13882 CORO1A; coronin-1A
K14949 pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
|
09174 Infectious disease: parasitic
|
05146 Amoebiasis [PATH:ko05146]
|
05144 Malaria [PATH:ko05144]
|
05145 Toxoplasmosis [PATH:ko05145]
|
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K06752 MHC2; MHC class II antigen
K14139 IRGM, LRG47; immunity-related GTPase family M protein [EC:3.6.5.-]
K14140 IGTP; interferon gamma induced GTPase
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K14141 PFNL; profilin-like protein
K14142 TLR11; toll-like receptor 11
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4, CD284; toll-like receptor 4
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K10159 TLR2, CD282; toll-like receptor 2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06485 ITGA6, CD49f; integrin alpha 6
K05719 ITGB1, CD29; integrin beta 1
K14143 SAG; major surface antigen
K14144 MIC3; microneme protein
K13412 CPK; calcium-dependent protein kinase [EC:2.7.11.1]
K13845 AMA-1; apical merozoite antigen 1
K14145 RON2; rhoptry neck protein 2
K14146 RON4; rhoptry neck protein 4
K12473 LDLR; low-density lipoprotein receptor
K14147 GRA7; dense granule protein 7
K14148 ROP2; rhoptry protein 2
K14149 GRA3; dense granule protein 3
K14150 GRA5; dense granule protein 5
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K04180 CCR5, CD195; C-C chemokine receptor type 5
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K14151 ROP16; rhoptry protein 16
K05443 IL10, CSIF; interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K23534 PP2CHN; protein phosphatase [EC:3.1.3.16]
|
05140 Leishmaniasis [PATH:ko05140]
|
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05430 IL4; interleukin 4
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03990 C3; complement component 3
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K01404 GP63; leishmanolysin [EC:3.4.24.36]
K06483 ITGA4, CD49d; integrin alpha 4
K05719 ITGB1, CD29; integrin beta 1
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K06752 MHC2; MHC class II antigen
K13536 MARCKSL1, MRP; MARCKS-related protein
K13537 CPB; cysteine peptidase B [EC:3.4.22.-]
K03231 EEF1A; elongation factor 1-alpha
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
|
05142 Chagas disease [PATH:ko05142]
|
K10160 TLR4, CD284; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K13729 TCAC2, TC52; thiol-dependent reductase 1
K10159 TLR2, CD282; toll-like receptor 2
K10169 TLR6, CD286; toll-like receptor 6
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05415 IFNB; interferon beta
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2, MCP1; C-C motif chemokine 2
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K05408 CCL3; C-C motif chemokine 3
K04519 IL1B; interleukin 1 beta
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K23590 CRP; complement regulatory protein
K03990 C3; complement component 3
K08057 CALR; calreticulin
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K08571 E3.4.22.51; cruzipain [EC:3.4.22.51]
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
K03898 KNG, BK; kininogen
K03916 BDKRB2; bradykinin receptor B2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K23591 TS; trans-sialidase [EC:3.2.1.-]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K05429 IL2; interleukin 2
|
05143 African trypanosomiasis [PATH:ko05143]
|
|
09163 Immune disease
|
|
09164 Neurodegenerative disease
|
05010 Alzheimer disease [PATH:ko05010]
|
05012 Parkinson disease [PATH:ko05012]
|
05014 Amyotrophic lateral sclerosis [PATH:ko05014]
|
K04451 TP53, P53; tumor protein p53
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04726 BID; BH3 interacting domain death agonist
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K11518 TOM40; mitochondrial import receptor subunit TOM40
K20858 MCU; calcium uniporter protein, mitochondrial
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K04556 PARK2; parkin [EC:2.3.2.31]
K19946 OPTN, FIP2; optineurin
K14381 SQSTM1; sequestosome 1
K10435 MAP1LC; microtubule-associated protein 1 light chain
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K23610 WDR41; WD repeat-containing protein 41
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K07874 RAB1A; Ras-related protein Rab-1A
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN, VPS30, ATG6; beclin
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K04575 ALS2; amyotrophic lateral sclerosis 2 protein
K07887 RAB5A; Ras-related protein Rab-5A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K12192 CHMP2B; charged multivesicular body protein 2B
K22913 FIG4; phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]
K19026 SPG11; spatacsin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04523 UBQLN, DSK2; ubiquilin
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
K11519 DERL1; Derlin-1
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K23600 TARDBP, TDP43; TAR DNA-binding protein 43
K13098 TLS, FUS; RNA-binding protein FUS
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
K23625 ATXN2_2L; ataxin 2/2L
K13213 MATR3; matrin 3
K16631 ANG, RNASE5; angiogenin [EC:3.1.27.-]
K12882 NCBP1, CBP80; nuclear cap-binding protein subunit 1
K12881 THOC4, ALY; THO complex subunit 4
K12892 SRSF3, SFRS3; serine/arginine-rich splicing factor 3
K12896 SRSF7, SFRS7; serine/arginine-rich splicing factor 7
K14284 NXF, TAP, MEX67; nuclear RNA export factor
K14285 NXT1_2, P15; NTF2-related export protein 1/2
K18723 GLE1; nucleoporin GLE1
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K14295 NUP50, NPAP60; nuclear pore complex protein Nup50
K14296 NUP153; nuclear pore complex protein Nup153
K14297 NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
K14298 RAE1, GLE2; mRNA export factor
K14004 SEC13; protein transport protein SEC13
K14299 SEH1; nucleoporin SEH1
K14300 NUP133; nuclear pore complex protein Nup133
K14301 NUP107, NUP84; nuclear pore complex protein Nup107
K14302 NUP37; nuclear pore complex protein Nup37
K14303 NUP160, NUP120; nuclear pore complex protein Nup160
K14304 NUP85; nuclear pore complex protein Nup85
K14305 NUP43; nuclear pore complex protein Nup43
K14306 NUP62, NSP1; nuclear pore complex protein Nup62
K14307 NUPL1, NUP49; nucleoporin p58/p45
K14308 NUP54, NUP57; nuclear pore complex protein Nup54
K14309 NUP93, NIC96; nuclear pore complex protein Nup93
K14310 NUP205, NUP192; nuclear pore complex protein Nup205
K14311 NUP188; nuclear pore complex protein Nup188
K14312 NUP155, NUP170, NUP157; nuclear pore complex protein Nup155
K14313 NUP35, NUP53; nuclear pore complex protein Nup53
K14314 NUP210, GP210; nuclear pore complex protein Nup210
K14315 NDC1, TMEM48; nucleoporin NDC1
K14316 POM121, NUP121; nuclear pore complex protein Nup121
K14317 NUP214, CAN; nuclear pore complex protein Nup214
K14318 NUP88; nuclear pore complex protein Nup88
K12172 RANBP2, NUP358; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
K10706 SETX, ALS4; senataxin [EC:5.6.2.-]
K22759 CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K10707 VAPB, ALS8; vesicle-associated membrane protein-associated protein B
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K09027 XBP1; X box-binding protein 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K20719 SIGMAR1; sigma non-opioid intracellular receptor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K02308 DAXX; death-associated protein 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04569 CCS; copper chaperone for superoxide dismutase
K00432 gpx, btuE, bsaA; glutathione peroxidase [EC:1.11.1.9]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K07607 PRPH; peripherin
K04572 NEFL, NF-L; neurofilament light polypeptide
K04573 NEF3, NF-M; neurofilament medium polypeptide (neurofilament 3)
K04574 NEFH, NF-H; neurofilament heavy polypeptide
K05759 PFN; profilin
K05692 ACTB_G1; actin beta/gamma 1
K17095 ANXA7_11; annexin A7/11
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1, ARP1; centractin
K16576 ACTR10, ARP11; actin-related protein 10
K04647 HAP1; huntingtin-associated protein 1
K10408 DNAH; dynein axonemal heavy chain
K10410 DNALI; dynein axonemal light intermediate chain 1
K10409 DNAI1; dynein axonemal intermediate chain 1
K11143 DNAI2; dynein axonemal intermediate chain 2
K10411 DNAL1; dynein axonemal light chain 1
K10412 DNAL4; dynein axonemal light chain 4
K05613 SLC1A2, EAAT2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
|
05016 Huntington disease [PATH:ko05016]
|
05017 Spinocerebellar ataxia [PATH:ko05017]
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05020 Prion disease [PATH:ko05020]
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K05634 PRNP, PrP, CD230; prion protein
K06491 NCAM, CD56; neural cell adhesion molecule
K05635 LAMC1; laminin, gamma 1
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K09553 STIP1; stress-induced-phosphoprotein 1
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02159 BAX; apoptosis regulator BAX
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K20858 MCU; calcium uniporter protein, mitochondrial
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K02599 NOTCH1; Notch 1
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K09203 EGR1; early growth response protein 1
K12499 CCL5; C-C motif chemokine 5
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
|
05022 Pathways of neurodegeneration - multiple diseases [PATH:ko05022]
|
K04520 APP; amyloid beta A4 protein
K04380 MAPT, TAU; microtubule-associated protein tau
K04528 SNCA; alpha-synuclein
K23600 TARDBP, TDP43; TAR DNA-binding protein 43
K13098 TLS, FUS; RNA-binding protein FUS
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K23625 ATXN2_2L; ataxin 2/2L
K04533 HD; huntingtin
K23616 ATXN1_1L; ataxin 1/1L
K11863 ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
K05634 PRNP, PrP, CD230; prion protein
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K23932 SPTBN2; spectrin beta, non-erythrocytic 2
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04556 PARK2; parkin [EC:2.3.2.31]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K20719 SIGMAR1; sigma non-opioid intracellular receptor
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K11828 DLG4, PSD95; discs large protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04560 STX1A; syntaxin 1A
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
K11519 DERL1; Derlin-1
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
K03178 UBE1, UBA1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
K10698 UBE1L, UBA7; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
K04552 UBE2L3, UBCH7; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
K04553 UBE2L6, UBCH8; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
K04554 UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10578 UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04555 UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10575 UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04243 GPR37; prosaposin receptor
K04557 SEPT5, PNUTL1, CDCREL1; septin 5
K04558 SNCAIP; synphilin-1
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K10707 VAPB, ALS8; vesicle-associated membrane protein-associated protein B
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K09027 XBP1; X box-binding protein 1
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K02161 BCL2; apoptosis regulator Bcl-2
K05862 VDAC1; voltage-dependent anion channel protein 1
K11518 TOM40; mitochondrial import receptor subunit TOM40
K20858 MCU; calcium uniporter protein, mitochondrial
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K09488 TRAP1, HSP75; TNF receptor-associated protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04559 HIP1; huntingtin interacting protein 1
K04638 IFT57, HIPPI, ESRRBL1; intraflagellar transport protein 57
K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05687 PARK7; protein DJ-1 [EC:3.5.1.124]
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K19946 OPTN, FIP2; optineurin
K14381 SQSTM1; sequestosome 1
K10435 MAP1LC; microtubule-associated protein 1 light chain
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K23610 WDR41; WD repeat-containing protein 41
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K07874 RAB1A; Ras-related protein Rab-1A
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN, VPS30, ATG6; beclin
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
K04575 ALS2; amyotrophic lateral sclerosis 2 protein
K07887 RAB5A; Ras-related protein Rab-5A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K12192 CHMP2B; charged multivesicular body protein 2B
K22913 FIG4; phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]
K19026 SPG11; spatacsin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K02308 DAXX; death-associated protein 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04569 CCS; copper chaperone for superoxide dismutase
K00432 gpx, btuE, bsaA; glutathione peroxidase [EC:1.11.1.9]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K07607 PRPH; peripherin
K04572 NEFL, NF-L; neurofilament light polypeptide
K04573 NEF3, NF-M; neurofilament medium polypeptide (neurofilament 3)
K04574 NEFH, NF-H; neurofilament heavy polypeptide
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K04355 BDNF; brain-derived neurotrophic factor
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1, ARP1; centractin
K16576 ACTR10, ARP11; actin-related protein 10
K04647 HAP1; huntingtin-associated protein 1
K10408 DNAH; dynein axonemal heavy chain
K10410 DNALI; dynein axonemal light intermediate chain 1
K10409 DNAI1; dynein axonemal intermediate chain 1
K11143 DNAI2; dynein axonemal intermediate chain 2
K10411 DNAL1; dynein axonemal light chain 1
K10412 DNAL4; dynein axonemal light chain 4
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02165 DKK1_2_4; dickkopf 1/2/4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
|
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09165 Substance dependence
|
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09166 Cardiovascular disease
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05417 Lipid and atherosclerosis [PATH:ko05417]
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K14462 APOB; apolipoprotein B
K08760 APOA4; apolipoprotein A-IV
K08757 APOA1; apolipoprotein A-I
K12473 LDLR; low-density lipoprotein receptor
K08763 OLR1; oxidised low-density lipoprotein receptor 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K04513 RHOA; Ras homolog gene family, member A
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K09364 POU2F, OTF; POU domain transcription factor, class 2
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17709 CYP2B6; cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17718 CYP2C8; cytochrome P450 family 2 subfamily C8 [EC:1.14.14.1]
K17719 CYP2C9; cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K04393 CDC42; cell division control protein 42
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K14624 CCL2, MCP1; C-C motif chemokine 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K10030 IL8, CXCL8; interleukin 8
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K06494 SELE, CD62E; selectin, endothelial cell
K06496 SELP, CD62P; selectin, platelet
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K26598 HSPA2; heat shock 70kDa protein 2
K09489 HSPA4; heat shock 70kDa protein 4
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K10159 TLR2, CD282; toll-like receptor 2
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4, CD284; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K06259 CD36; CD36 antigen
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K10169 TLR6, CD286; toll-like receptor 6
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K12499 CCL5; C-C motif chemokine 5
K05408 CCL3; C-C motif chemokine 3
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K05482 IL18, IL1F4; interleukin 18
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K10950 ERO1L; ERO1-like protein alpha [EC:1.8.4.-]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K09027 XBP1; X box-binding protein 1
K05641 ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
K05679 ABCG1; ATP-binding cassette, subfamily G (WHITE), member 1
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K20053 VLDLR; very low-density lipoprotein receptor
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04451 TP53, P53; tumor protein p53
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05418 Fluid shear stress and atherosclerosis [PATH:ko05418]
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K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K02183 CALM; calmodulin
K08107 GPC1; glypican 1
K06257 SDC1, CD138; syndecan 1
K16336 SDC2, CD362; syndecan 2
K16338 SDC4; syndecan 4
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K14381 SQSTM1; sequestosome 1
K03671 TXN, trxA; thioredoxin
K12336 NPPC; natriuretic peptide C
K01940 argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]
K03907 THBD, CD141; thrombomodulin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K02105 CTNNB1; catenin beta 1
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K17845 KLF2; krueppel-like factor 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K12791 ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
K04513 RHOA; Ras homolog gene family, member A
K05692 ACTB_G1; actin beta/gamma 1
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K16864 MIR10A; microRNA 10a
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K20607 MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K14624 CCL2, MCP1; C-C motif chemokine 2
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K16366 EDN1; endothelin-1
K05448 VEGFA; vascular endothelial growth factor A
K04662 BMP4; bone morphogenetic protein 4
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K08008 NOX1, MOX1; NADPH oxidase 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K12160 SUMO, SMT3; small ubiquitin-related modifier
K02161 BCL2; apoptosis regulator Bcl-2
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05410 Hypertrophic cardiomyopathy [PATH:ko05410]
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05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:ko05412]
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05414 Dilated cardiomyopathy [PATH:ko05414]
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05415 Diabetic cardiomyopathy [PATH:ko05415]
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K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07191 SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K12044 TNNI3; troponin I, cardiac muscle
K04962 RYR2; ryanodine receptor 2
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04684 SP1; transcription factor Sp1
K09821 AGT, SERPINA8; angiotensinogen
K01380 REN; renin [EC:3.4.23.15]
K01329 CMA1; chymase [EC:3.4.21.39]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04166 AGTR1; angiotensin II receptor type 1
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K06259 CD36; CD36 antigen
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K17605 PPP2R4, PTPA; serine/threonine-protein phosphatase 2A activator
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K08766 CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K17902 TBC1D4, AS160; TBC1 domain family member 4
K22138 MPC1; mitochondrial pyruvate carrier 1
K22139 MPC2; mitochondrial pyruvate carrier 2
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K00036 G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00383 GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
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05416 Viral myocarditis [PATH:ko05416]
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09167 Endocrine and metabolic disease
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04930 Type II diabetes mellitus [PATH:ko04930]
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04940 Type I diabetes mellitus [PATH:ko04940]
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04950 Maturity onset diabetes of the young [PATH:ko04950]
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04936 Alcoholic liver disease [PATH:ko04936]
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K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K03990 C3; complement component 3
K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
K03994 C5; complement component 5
K04010 C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4, CD284; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K10030 IL8, CXCL8; interleukin 8
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05489 IL17A, CTLA8; interleukin 17A
K05164 IL17RA, CD217; interleukin 17 receptor A
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07197 SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K17125 MIR217; microRNA 217
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K12897 TRA2; transformer-2 protein
K07296 ADIPOQ, ACDC; adiponectin
K07297 ADIPOR; adiponectin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K07202 PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K09479 ACADVL; very long chain acyl-CoA dehydrogenase [EC:1.3.8.9]
K00249 ACADM, acd; acyl-CoA dehydrogenase [EC:1.3.8.7]
K00232 E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
K08750 FABP1, L-FABP; fatty acid-binding protein 1, liver
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA, ADH5, adhC; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K14085 ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K00149 ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
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04932 Non-alcoholic fatty liver disease [PATH:ko04932]
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K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K08536 NR1H3, LXRA; liver X receptor alpha
K08524 RXRA, NR2B1; retinoid X receptor alpha
K07197 SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
K09113 MLX; MAX-like protein X
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K05424 LEP; leptin
K05062 LEPR, CD295; leptin receptor
K07296 ADIPOQ, ACDC; adiponectin
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05632 ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K09027 XBP1; X box-binding protein 1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K10030 IL8, CXCL8; interleukin 8
K13375 TGFB1; transforming growth factor beta-1
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K02159 BAX; apoptosis regulator BAX
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
|
04931 Insulin resistance [PATH:ko04931]
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ko04933]
|
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K05717 FN1; fibronectin 1
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K09821 AGT, SERPINA8; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K14624 CCL2, MCP1; C-C motif chemokine 2
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K06494 SELE, CD62E; selectin, endothelial cell
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03901 F3, CD142; coagulation factor III (tissue factor)
K16366 EDN1; endothelin-1
K03907 THBD, CD141; thrombomodulin
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05740 DIAPH1; diaphanous 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04393 CDC42; cell division control protein 42
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K07201 FOXO1; forkhead box protein O1
K02161 BCL2; apoptosis regulator Bcl-2
K02159 BAX; apoptosis regulator BAX
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K11220 STAT1; signal transducer and activator of transcription 1
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K09203 EGR1; early growth response protein 1
|
04934 Cushing syndrome [PATH:ko04934]
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
01521 EGFR tyrosine kinase inhibitor resistance [PATH:ko01521]
|
01524 Platinum drug resistance [PATH:ko01524]
|
01523 Antifolate resistance [PATH:ko01523]
|
01522 Endocrine resistance [PATH:ko01522]
|
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K05664 ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K15144 MED1; mediator of RNA polymerase II transcription subunit 1
K05931 CARM1, PRMT4; type I protein arginine methyltransferase [EC:2.1.1.319]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04650 NCOR1, N-CoR; nuclear receptor co-repressor 1
K04246 GPER1, GPR30; G-protein coupled estrogen receptor 1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02161 BCL2; apoptosis regulator Bcl-2
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K18452 BIK; Bcl-2-interacting killer
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
|
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09180 Brite Hierarchies
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09181 Protein families: metabolism
|
01000 Enzymes [BR:ko01000]
|
01001 Protein kinases [BR:ko01001]
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K04345 PKA; protein kinase A [EC:2.7.11.11]
K19584 PRKX; protein kinase X [EC:2.7.11.11]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18051 PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K11479 AURKB; aurora kinase B [EC:2.7.11.1]
K11480 AURKC; aurora kinase C [EC:2.7.11.1]
K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K19800 SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K20839 RSKL; ribosomal protein S6 kinase-like
K22008 PSK1; serine/threonine-protein kinase Psk1 [EC:2.7.11.1]
K08790 STK38, NDR; serine/threonine kinase 38 [EC:2.7.11.1]
K08791 LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08789 MAST; microtubule-associated serine/threonine kinase [EC:2.7.11.1]
K16309 MASTL, GW; serine/threonine-protein kinase greatwall [EC:2.7.11.1]
K12767 RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.1]
K08793 STK32, YANK; serine/threonine kinase 32 [EC:2.7.11.1]
K08788 DMPK; dystrophia myotonica-protein kinase [EC:2.7.11.1]
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
K16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K17529 SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1]
K20714 OXI1; serine/threonine-protein kinase OXI1 [EC:2.7.11.1]
K20715 PHOT; phototropin [EC:2.7.11.1]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K08795 PNCK; pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17]
K08812 CAMKV; CaM kinase-like vesicle-associated [EC:2.7.11.-]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K08797 HUNK; hormonally upregulated Neu-associated kinase [EC:2.7.11.1]
K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
K08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
K16310 NIM1; serine/threonine-protein kinase NIM1 [EC:2.7.11.1]
K08800 NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
K08801 PASK; PAS domain containing serine/threonine kinase [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
K19009 SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
K08802 SNRK; SNF related kinase [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K14498 SNRK2; serine/threonine-protein kinase SRK2 [EC:2.7.11.1]
K12761 SNF1; carbon catabolite-derepressing protein kinase [EC:2.7.11.1]
K18639 KCC4; serine/threonine-protein kinase KCC4 [EC:2.7.11.1]
K06668 GIN4; serine/threonine-protein kinase GIN4 [EC:2.7.11.-]
K02515 HSL1; serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]
K18680 CDR1; mitosis inducer protein kinase Cdr1 [EC:2.7.11.1]
K18679 CDR2; mitosis inducer protein kinase Cdr2 [EC:2.7.11.1]
K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
K17530 DCLK3; doublecortin-like kinase 3 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04442 MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12567 TTN; titin [EC:2.7.11.1]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K08807 PIM3; proto-oncogene serine/threonine-protein kinase Pim-3 [EC:2.7.11.1]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K12776 MEK1; meiosis-specific serine/threonine-protein kinase MEK1 [EC:2.7.11.1]
K08809 SPEG; striated muscle-specific serine/threonine protein kinase [EC:2.7.11.1]
K08810 TRIO; triple functional domain protein [EC:2.7.11.1]
K15048 KALRN; kalirin [EC:2.7.11.1]
K17531 OBSCN, ARHGEF30; obscurin-RhoGEF [EC:2.7.11.1]
K08811 TSSK, STK22; testis-specific serine kinase [EC:2.7.11.1]
K13412 CPK; calcium-dependent protein kinase [EC:2.7.11.1]
K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
K08814 TRIB1_2; tribbles homolog 1/2
K19518 TRIB3; tribbles homolog 3
K08813 STK33; serine/threonine kinase 33 [EC:2.7.11.1]
K16312 STK40, SHIK; serine/threonine-protein kinase 40 [EC:2.7.11.1]
K23785 RCK2, CLK1; serine/threonine-protein kinase RCK2 [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02218 CSNK1, CKI; casein kinase 1 [EC:2.7.11.1]
K19830 YCK3; casein kinase I homolog 3 [EC:2.7.11.1]
K14758 HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]
K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02088 CDK3; cyclin-dependent kinase 3 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
K08821 CDK14, PFTK1; cyclin-dependent kinase 14 [EC:2.7.11.22]
K15594 CDK15, PFTK2; cyclin-dependent kinase 15 [EC:2.7.11.22]
K08820 CDK16, PCTK1; cyclin-dependent kinase 16 [EC:2.7.11.22]
K15595 CDK17, PCTK2; cyclin-dependent kinase 17 [EC:2.7.11.22]
K15596 CDK18, PCTK3; cyclin-dependent kinase 18 [EC:2.7.11.22]
K07760 CDK; cyclin-dependent kinase [EC:2.7.11.22]
K15562 BUR1, SGV1; serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]
K00916 CTK1; CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K20535 MPK1_2; mitogen-activated protein kinase 1/2 [EC:2.7.11.24]
K20536 MPK3; mitogen-activated protein kinase 3 [EC:2.7.11.24]
K20600 MPK4; mitogen-activated protein kinase 4 [EC:2.7.11.24]
K14512 MPK6; mitogen-activated protein kinase 6 [EC:2.7.11.24]
K20537 MPK7_14; mitogen-activated protein kinase 7/14 [EC:2.7.11.24]
K20538 MPK8; mitogen-activated protein kinase 8 [EC:2.7.11.24]
K08293 SMK1; sporulation-specific mitogen-activated protein kinase SMK1 [EC:2.7.11.24]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K27413 ASK1_3_5; shaggy-related protein kinase [EC:2.7.11.1]
K27414 ASK2_8; shaggy-related protein kinase [EC:2.7.11.1]
K14502 ASK6_7_9, BIN2; shaggy-related protein kinase (protein brassinosteroid insensitive 2) [EC:2.7.11.1]
K12766 MDS1, RIM11; serine/threonine-protein kinase MDS1/RIM11 [EC:2.7.11.1]
K23561 CLK1_4; dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
K18670 YAK1; dual specificity protein kinase YAK1 [EC:2.7.12.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
K08828 ICK; intestinal cell (MAK-like) kinase [EC:2.7.11.22]
K08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]
K08830 RAGE, MOK; renal tumor antigen [EC:2.7.11.22]
K12765 IME2; meiosis induction protein kinase IME2/SME1 [EC:2.7.11.1]
K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
K08831 SRPK2; serine/threonine-protein kinase SRPK2 [EC:2.7.11.1]
K08832 SRPK3, STK23; serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K08294 MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K11226 STE7; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K11227 PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
K19763 JKK1; dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2]
K20602 MEK1, MKK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K20603 MKK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K20607 MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K13413 MKK4_5; mitogen-activated protein kinase kinase 4/5 [EC:2.7.12.2]
K20604 MKK9; mitogen-activated protein kinase kinase 9 [EC:2.7.12.2]
K04408 MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04414 MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04406 MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K08833 MAP4K5, KHS1; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
K04413 MINK; misshapen/NIK-related kinase [EC:2.7.11.1]
K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
K16313 NRK; Nik-related protein kinase [EC:2.7.11.1]
K08834 MYO3, DFNB30; myosin III [EC:2.7.11.1]
K08835 OXSR1, STK39; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K19833 CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
K08836 SLK; STE20-like kinase [EC:2.7.11.1]
K08837 STK10, LOK; serine/threonine kinase 10 [EC:2.7.11.1]
K08271 STRADA, LYK5; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K04412 STK3, MST2; serine/threonine kinase 3
K04411 STK4, MST1; serine/threonine kinase 4
K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K12771 SPS1; sporulation-specific protein 1 [EC:2.7.11.1]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04425 MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K13986 MAP3K15; mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25]
K17533 MAP3K19, YSK4; mitogen-activated protein kinase kinase kinase 19 [EC:2.7.11.25]
K13414 MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K20605 MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K20606 ANP1; mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25]
K20716 MAPKKK17_18; mitogen-activated protein kinase kinase kinase 17/18
K20717 YDA; mitogen-activated protein kinase kinase kinase YODA [EC:2.7.11.25]
K11228 STE11; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K11229 BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K11230 SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K13415 BRI1; protein brassinosteroid insensitive 1 [EC:2.7.10.1 2.7.11.1]
K13416 BAK1; brassinosteroid insensitive 1-associated receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
K13417 SERK4, BKK1; somatic embryogenesis receptor kinase 4 [EC:2.7.10.1 2.7.11.1]
K13418 SERK1; somatic embryogenesis receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
K13420 FLS2; LRR receptor-like serine/threonine-protein kinase FLS2 [EC:2.7.11.1]
K13428 EFR; LRR receptor-like serine/threonine-protein kinase EFR [EC:2.7.11.1]
K20718 ER; LRR receptor-like serine/threonine-protein kinase ERECTA [EC:2.7.11.1]
K14500 BSK; BR-signaling kinase [EC:2.7.11.1]
K00924 TMK; receptor protein kinase TMK [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K08841 TESK1; testis-specific kinase 1 [EC:2.7.12.1]
K08842 TESK2; testis-specific kinase 2 [EC:2.7.12.1]
K08843 LRRK1; leucine-rich repeat kinase 1 [EC:2.7.11.1]
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K17534 MLK4, KIAA1804; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04424 ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04423 MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K17535 TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K14510 CTR1; serine/threonine-protein kinase CTR1 [EC:2.7.11.1]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K08848 RIPK4; receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1]
K16289 ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1]
K16279 KEG; E3 ubiquitin-protein ligase KEG [EC:2.7.11.1 2.3.2.27]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K08851 TP53RK, PRPK, BUD32; TP53 regulating kinase and related kinases [EC:2.7.11.1]
K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
K00908 CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K11715 ERN2; serine/threonine-protein kinase/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
K08854 BMP2K, BIKE; BMP2 inducible kinase [EC:2.7.11.1]
K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
K20873 NEK3; serine/threonine-protein kinase Nek3 [EC:2.7.11.1]
K20875 NEK6; serine/threonine-protein kinase Nek6 [EC:2.7.11.34]
K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
K20877 NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
K20878 NEK9, NERCC1; serine/threonine-protein kinase Nek9 [EC:2.7.11.1]
K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K17537 SGK223; tyrosine-protein kinase SgK223 [EC:2.7.10.2]
K17538 PEAK1, SGK269; pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2]
K08859 STK35, PDIK1, CLIK1; serine/threonine kinase 35 [EC:2.7.11.1]
K17539 PDIK1L, CLIK1L; serine/threonine-protein kinase PDIK1L [EC:2.7.11.1]
K17540 TEX14, SGK307; inactive serine/threonine-protein kinase TEX14
K08875 NRBP; nuclear receptor-binding protein
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K08876 SCYL1; SCY1-like protein 1
K17541 SCYL2; SCY1-like protein 2
K17542 SCYL3; SCY1-like protein 3
K17543 PXK; PX domain-containing protein kinase-like protein
K17544 TBCK; TBC domain-containing protein kinase-like protein
K08864 TLK; tousled-like kinase [EC:2.7.11.1]
K08865 PBK; PDZ-binding kinase [EC:2.7.12.2]
K08866 TTK, MPS1; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K06228 FU; fused [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K21358 ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
K17545 ULK4; serine/threonine-protein kinase ULK4 [EC:2.7.11.1]
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K08867 WNK, PRKWNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08869 ADCK, ABC1; aarF domain-containing kinase
K08868 ALPK; alpha-kinase
K04981 TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K08871 BRD2; bromodomain-containing protein 2
K11721 BRD3; bromodomain-containing protein 3
K11722 BRD4; bromodomain-containing protein 4
K11724 BRDT; bromodomain testis-specific protein
K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
K08880 STK19; serine/threonine kinase 19 [EC:2.7.11.1]
K08879 HSPB8; heat shock protein beta-8
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
K00905 BCKDK; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4]
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
K08874 TRRAP; transformation/transcription domain-associated protein
K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
K08872 RIOK3, SUDD; RIO kinase 3 [EC:2.7.11.1]
K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K08881 TRIM24, TIF1A; tripartite motif-containing protein 24 [EC:2.3.2.27]
K08882 TRIM28, TIF1B; tripartite motif-containing protein 28 [EC:2.3.2.27]
K08883 TRIM33, TIF1G; tripartite motif-containing protein 33 [EC:2.3.2.27]
K08877 UHMK1, KIS; serine/threonine-protein kinase Kist [EC:2.7.11.1]
K11789 DCAF1, VPRBP; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
K16316 STK31, TDRD8; serine/threonine-protein kinase 31 [EC:2.7.11.1]
K17547 SGK196; glycoprotein-mannosyl O6-kinase [EC:2.7.1.183]
K16288 DSTYK, RIPK5; dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
K17546 STKLD1; serine/threonine kinase-like domain-containing protein STKLD1
K13429 CERK1; chitin elicitor receptor kinase 1
K13430 PBS1; serine/threonine-protein kinase PBS1 [EC:2.7.11.1]
K13435 PTO; serine/threonine-protein kinase Pto
K13436 PTI1; pto-interacting protein 1 [EC:2.7.11.1]
K13437 XA21; receptor kinase-like protein
K16224 FRK1; senescence-induced receptor-like serine/threonine-protein kinase
K16314 ELM1; serine/threonine-protein kinase ELM1 [EC:2.7.11.1]
K21157 SAK1; SNF1-activating kinase 1 [EC:2.7.11.1]
K21158 TOS3; serine/threonine-protein kinase TOS3 [EC:2.7.11.1]
K22009 MCK1; protein kinase MCK1
K11889 impN; type VI secretion system protein ImpN [EC:2.7.11.1]
K11912 ppkA; serine/threonine-protein kinase PpkA [EC:2.7.11.1]
K14949 pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
K22893 pknH; serine/threonine kinase PknH [EC:2.7.11.1]
K13419 pknK; serine/threonine-protein kinase PknK [EC:2.7.11.1]
K12132 prkC, stkP; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
K23472 ypkA, yopO; serine/threonine protein kinase YpkA [EC:2.7.11.1]
K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
K15486 legK1; serine/threonine-protein kinase LegK1 [EC:2.7.1.-]
K17752 rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
K04757 rsbW; serine/threonine-protein kinase RsbW [EC:2.7.11.1]
K08884 K08884; serine/threonine protein kinase, bacterial [EC:2.7.11.1]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K13594 ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04669 TGFBRX; TGF-beta receptor, other
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05100 MST1R, RON, CD136; macrophage-stimulating 1 receptor [EC:2.7.10.1]
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K05102 EPHA1, EPH; Eph receptor A1 [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05104 EPHA3, HEK, TYRO4; Eph receptor A3 [EC:2.7.10.1]
K05105 EPHA4, SEK, TYRO1; Eph receptor A4 [EC:2.7.10.1]
K05106 EPHA5, EHK1, TYRO4; Eph receptor A5 [EC:2.7.10.1]
K05107 EPHA6, EHK2; Eph receptor A6 [EC:2.7.10.1]
K05108 EPHA7, EHK3, HEK11; EphA7 [EC:2.7.10.1]
K05109 EPHA8, EEK; Eph receptor A8 [EC:2.7.10.1]
K08897 EPHA10; Eph receptor A10 [EC:2.7.10.1]
K05110 EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
K05111 EPHB2, ERK, DRT; Eph receptor B2 [EC:2.7.10.1]
K05112 EPHB3, HEK2, ETK2; Eph receptor B3 [EC:2.7.10.1]
K05113 EPHB4, HTK; Eph receptor B4 [EC:2.7.10.1]
K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
K05115 AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05116 TYRO3, RSE; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]
K05117 MERTK, MER; c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K05118 LTK; leukocyte tyrosine kinase [EC:2.7.10.1]
K05120 TIE1; tyrosine kinase receptor 1 [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05122 ROR1, NTRKR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
K05123 ROR2, NTRKR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
K05124 DDR1, NEP, CD167a; discoidin domain receptor family member 1 [EC:2.7.10.1]
K05125 DDR2, TKT, CD167b; discoidin domain receptor family member 2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
K05127 PTK7, CCK4; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
K17480 AATK, LMTK1; lemur tyrosine kinase 1 [EC:2.7.10.1]
K08898 LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
K08899 LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K08885 TNK1; non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2]
K08886 TNK2, ACK1; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K07527 FES, FPS; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
K08889 FER, TYK3; tyrosine-protein kinase Fer [EC:2.7.10.2]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K08890 BLK; B lymphoid tyrosine kinase [EC:2.7.10.2]
K08891 FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
K08892 FRK, PTK5; fyn-related kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K08894 PTK6, BRK; protein tyrosine kinase 6 [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K08895 SRMS; tyrosine-protein kinase Srms [EC:2.7.10.2]
K05705 YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
K17511 YRK; proto-oncogene tyrosine-protein kinase YRK [EC:2.7.10.2]
K08896 BMX, ETK; cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K08016 TXK, RLK; tyrosine-protein kinase TXK [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
K17510 STYK1; tyrosine-protein kinase STYK1 [EC:2.7.10.2]
K17548 PKDCC; extracellular tyrosine-protein kinase PKDCC [EC:2.7.10.2]
K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
K16554 exoP, vpsO; polysaccharide biosynthesis transport protein [EC:2.7.10.3]
K00903 epsB, capB; protein-tyrosine kinase [EC:2.7.10.3]
K25588 K25588; tyrosine-protein kinase [EC:2.7.10.3]
K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
K07650 cssS; two-component system, OmpR family, sensor histidine kinase CssS [EC:2.7.13.3]
K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
K07642 baeS, smeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
K07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
K07644 cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
K07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
K07653 mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
K07654 mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
K07655 prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
K07656 trcS; two-component system, OmpR family, sensor histidine kinase TrcS [EC:2.7.13.3]
K11328 nrsS, rppB; two-component system, OmpR family, Ni(II)-sensor and/or redox sensor kinase NrsS [EC:2.7.13.3]
K11520 manS; two-component system, OmpR family, manganese sensing sensor histidine kinase [EC:2.7.13.3]
K07769 nblS, dfr, dspA, hik33; two-component system, OmpR family, sensor histidine kinase NblS [EC:2.7.13.3]
K08479 sasA; two-component system, OmpR family, clock-associated histidine kinase SasA [EC:2.7.13.3]
K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]
K11629 bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]
K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3]
K19081 braS, bceS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
K11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]
K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
K18345 vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
K18350 vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
K18351 vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]
K19609 pfeS, pirS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]
K20487 nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]
K07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]
K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
K07678 barA, gacS, varS; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
K07679 evgS, bvgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
K07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
K07681 vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3]
K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
K07682 devS; two-component system, NarL family, sensor histidine kinase DevS [EC:2.7.13.3]
K27105 dosT; two-component system, NarL family, sensor histidine kinase DosT [EC:2.7.13.3]
K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
K11623 ydfH; two-component system, NarL family, sensor histidine kinase YdfH [EC:2.7.13.3]
K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]
K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
K07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]
K07698 kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]
K13532 kinD; two-component system, sporulation sensor kinase D [EC:2.7.13.3]
K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
K07700 dpiB, citA; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
K11637 citS; two-component system, CitB family, sensor histidine kinase CitS [EC:2.7.13.3]
K07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]
K11691 K11691, dctS; two-component system, CitB family, sensor histidine kinase DctS [EC:2.7.13.3]
K11614 yufL, malK; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]
K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
K11640 natK; two-component system, LytTR family, sensor histidine kinase NatK [EC:2.7.13.3]
K07706 agrC, blpH, fsrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K20339 agrC2; two-component system, LytTR family, sensor histidine kinase AgrC2 [EC:2.7.13.3]
K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3]
K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
K07708 glnL, ntrB; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
K07709 zraS, hydH; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
K02668 pilS, pehS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
K07711 glrK, qseE; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
K08475 pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]
K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
K19661 hupT, hoxJ; two-component system, NtrC family, sensor histidine kinase HupT/HoxJ [EC:2.7.13.3]
K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
K11526 pixL; two-component system, chemotaxis family, sensor histidine kinase and response regulator PixL
K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
K11357 divJ; two-component system, cell cycle sensor histidine kinase DivJ [EC:2.7.13.3]
K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
K02489 hk1; two-component system, glycerol uptake and utilization sensor kinase [EC:2.7.13.3]
K10909 luxQ; two-component system, autoinducer 2 sensor kinase/phosphatase LuxQ [EC:2.7.13.3 3.1.3.-]
K10916 cqsS; two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
K15850 luxN; two-component system, autoinducer 1 sensor kinase/phosphatase LuxN [EC:2.7.13.3 3.1.3.-]
K11711 dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]
K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
K14978 ssrA; two-component system, LuxR family, secretion system sensor histidine kinase SsrA
K10942 flrB, fleS, flaL; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
K11231 SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
K19690 CHK1; osomolarity two-component system, sensor histidine kinase CHK1 [EC:2.7.13.3]
K19691 NIK1, TCSC; osomolarity two-component system, sensor histidine kinase NIK1 [EC:2.7.13.3]
K19692 TCSA; osomolarity two-component system, sensor histidine kinase TcsA [EC:2.7.13.3]
K10715 rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
K07717 glnK; two-component system, sensor histidine kinase GlnK [EC:2.7.13.3]
K25212 hptS; two-component system, sensor histidine kinase HptS [EC:2.7.13.3]
K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
K11356 cikA; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
K15011 regB, regS, actS; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
K19616 fitF; two-component system, sensor histidine kinase and response regulator FitF [EC:2.7.13.3]
K19621 phcS; two-component system, sensor histidine kinase PhcS [EC:2.7.13.3]
K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
K19694 chiS; two-component system, sensor histidine kinase ChiS
K20971 ladS; two-component system, sensor histidine kinase LadS
K20972 retS; two-component system, sensor histidine kinase RetS
K02486 K02486; two-component system, sensor kinase [EC:2.7.13.3]
K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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01009 Protein phosphatases and associated proteins [BR:ko01009]
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01002 Peptidases and inhibitors [BR:ko01002]
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01003 Glycosyltransferases [BR:ko01003]
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01005 Lipopolysaccharide biosynthesis proteins [BR:ko01005]
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01011 Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
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01004 Lipid biosynthesis proteins [BR:ko01004]
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01008 Polyketide biosynthesis proteins [BR:ko01008]
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01006 Prenyltransferases [BR:ko01006]
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01007 Amino acid related enzymes [BR:ko01007]
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00199 Cytochrome P450 [BR:ko00199]
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00194 Photosynthesis proteins [BR:ko00194]
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09182 Protein families: genetic information processing
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09183 Protein families: signaling and cellular processes
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)