 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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 K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04375 ELK1; ETS domain-containing protein Elk-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
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04014 Ras signaling pathway [PATH:ko04014]
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K08052 NF1; neurofibromin 1
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K12380 RASA3; Ras GTPase-activating protein 3
K17630 RASA4, CAPRI; Ras GTPase-activating protein 4
K17631 SYNGAP, RASA5; Ras/Rap GTPase-activating protein SynGAP
K17632 RASAL1; RAS protein activator-like 1
K17633 RASAL2; RAS protein activator-like 2
K17634 RASAL3; RAS protein activator-like 3
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K12358 FOXO4; forkhead box protein O4
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K25768 RALGAPA; Ral GTPase-activating protein subunit alpha
K25769 RALGAPB; Ral GTPase-activating protein subunit beta
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K17635 RGL1, RGL; ral guanine nucleotide dissociation stimulator-like 1
K17636 RGL2; ral guanine nucleotide dissociation stimulator-like 2
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K17637 EXOC2, SEC5; exocyst complex component 2
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09254 REL; c-Rel proto-oncogene protein
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K05702 AF6, MLLT4; afadin
K19613 SHOC2, SUR8; leucine-rich repeat protein SHOC2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K13618 PLA1A; phosphatidylserine sn-1 acylhydrolase [EC:3.1.1.111]
K01047 PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K04375 ELK1; ETS domain-containing protein Elk-1
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K17638 RIN1; Ras and Rab interactor 1
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07941 ARF6; ADP-ribosylation factor 6
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04015 Rap1 signaling pathway [PATH:ko04015]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04341 Hedgehog signaling pathway - fly [PATH:ko04341]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway - fly [PATH:ko04391]
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04392 Hippo signaling pathway - multiple species [PATH:ko04392]
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04370 VEGF signaling pathway [PATH:ko04370]
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04371 Apelin signaling pathway [PATH:ko04371]
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04630 JAK-STAT signaling pathway [PATH:ko04630]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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04668 TNF signaling pathway [PATH:ko04668]
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04066 HIF-1 signaling pathway [PATH:ko04066]
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04068 FoxO signaling pathway [PATH:ko04068]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04072 Phospholipase D signaling pathway [PATH:ko04072]
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K04357 EGF; epidermal growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05461 KITLG; KIT ligand
K04526 INS; insulin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K07937 ARF1_2; ADP-ribosylation factor 1/2
K07941 ARF6; ADP-ribosylation factor 6
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06856 IGH; immunoglobulin heavy chain
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
K19007 AGPAT5; lysophosphatidiate acyltransferase [EC:2.3.1.51]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00901 dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K05242 AVP; arginine vasopressin
K10030 IL8, CXCL8; interleukin 8
K04166 AGTR1; angiotensin II receptor type 1
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04603 GRM1; metabotropic glutamate receptor 1
K04605 GRM2; metabotropic glutamate receptor 2
K04606 GRM3; metabotropic glutamate receptor 3
K04607 GRM4; metabotropic glutamate receptor 4
K04604 GRM5; metabotropic glutamate receptor 5
K04608 GRM6; metabotropic glutamate receptor 6
K04609 GRM7; metabotropic glutamate receptor 7
K04610 GRM8; metabotropic glutamate receptor 8
K04226 AVPR1A; arginine vasopressin receptor 1A
K04227 AVPR1B; arginine vasopressin receptor 1B
K04228 AVPR2; arginine vasopressin receptor 2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04262 PTGFR; prostaglandin F receptor
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K18441 CYTH; cytohesin
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5]
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
04024 cAMP signaling pathway [PATH:ko04024]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
|
09152 Endocrine system
|
|
09153 Circulatory system
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
04724 Glutamatergic synapse [PATH:ko04724]
|
04727 GABAergic synapse [PATH:ko04727]
|
04725 Cholinergic synapse [PATH:ko04725]
|
04728 Dopaminergic synapse [PATH:ko04728]
|
04726 Serotonergic synapse [PATH:ko04726]
|
04720 Long-term potentiation [PATH:ko04720]
|
04730 Long-term depression [PATH:ko04730]
|
04723 Retrograde endocannabinoid signaling [PATH:ko04723]
|
04721 Synaptic vesicle cycle [PATH:ko04721]
|
04722 Neurotrophin signaling pathway [PATH:ko04722]
|
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K12457 NTF4; neurotrophin 4
K04356 NTF3; neurotrophin 3
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K07193 SH2B, APS; SH2B adapter protein 2
K12459 SH2B1_3; SH2B adaptor protein 1/3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K02161 BCL2; apoptosis regulator Bcl-2
K12460 KIDINS220, ARMS; ankyrin repeat-rich membrane spanning protein
K12461 FRS2; fibroblast growth factor receptor substrate 2
K04438 CRK, CRKII; C-crk adapter molecule crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K09593 GAB1; GRB2-associated-binding protein 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K09408 FOXO3; forkhead box protein O3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K12462 ARHGDI, RHOGDI; Rho GDP-dissociation inhibitor
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04451 TP53, P53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K10148 TP73; tumor protein p73
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12458 ZNF274; zinc finger protein 274
K12463 PRDM4; PR domain zinc finger protein 4 [EC:2.1.1.-]
K12464 MAGED1, NRAGE; melanoma-associated antigen D1
K12465 NGFRAP1; nerve growth factor receptor-associated protein 1
K06630 YWHAE; 14-3-3 protein epsilon
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K12388 SORT1; sortilin
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
|
09149 Aging
|
|
09159 Environmental adaptation
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
K06256 CD44; CD44 antigen
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06106 CTTN, EMS1; cortactin
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K04393 CDC42; cell division control protein 42
K04375 ELK1; ETS domain-containing protein Elk-1
K08550 ESR1, NR3A1; estrogen receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K05692 ACTB_G1; actin beta/gamma 1
K04437 FLNA; filamin-A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10380 ANK1; ankyrin-1
K09255 ANK2, ANKB; ankyrin-2
K09259 ANK3, ANKG; ankyrin-3
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K10164 NANOG; homeobox protein Nanog
K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
K03685 rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
K04692 STAT3; signal transducer and activator of transcription 3
K16863 MIR21; microRNA 21
K09069 TWIST; twist
K16864 MIR10A; microRNA 10a
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K04660 DCN; decorin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K06497 CD63, MLA1, TSPAN30; CD63 antigen
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13375 TGFB1; transforming growth factor beta-1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K16865 PDCD4; programmed cell death protein 4
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05425 IL12B; interleukin 12B
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04377 MYC; Myc proto-oncogene protein
K02105 CTNNB1; catenin beta 1
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09108 TFAP4; transcription factor AP-4
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K16866 TIMP3; metalloproteinase inhibitor 3
K16857 THBS1; thrombospondin 1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08122 LUM; lumican
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K13376 TGFB2; transforming growth factor beta-2
K04500 SMAD2; mothers against decapentaplegic homolog 2
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K06257 SDC1, CD138; syndecan 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03985 PLAUR, CD87; plasminogen activator, urokinase receptor
K06236 COL1A; collagen type I alpha
K06481 ITGA2, CD49b; integrin alpha 2
K05719 ITGB1, CD29; integrin beta 1
K06251 VTN; vitronectin
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05717 FN1; fibronectin 1
K06588 ITGB5; integrin beta 5
K05460 HGF; hepatocyte growth factor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K06484 ITGA5, CD49e; integrin alpha 5
K16336 SDC2, CD362; syndecan 2
K08007 EZR, VIL2; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K16338 SDC4; syndecan 4
K18497 FGF2; fibroblast growth factor 2
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K12461 FRS2; fibroblast growth factor receptor substrate 2
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K16867 NUDT16L1, SDOS; NUDT16-like protein 1
K05760 PXN; paxillin
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08107 GPC1; glypican 1
K13769 IGF2; insulin-like growth factor 2
K08109 GPC3; glypican 3
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K11988 SHH; sonic hedgehog
K11989 IHH; indian hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K09543 HSPB2; heat shock protein beta-2
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:ko05210]
|
05212 Pancreatic cancer [PATH:ko05212]
|
05225 Hepatocellular carcinoma [PATH:ko05225]
|
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04375 ELK1; ETS domain-containing protein Elk-1
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04377 MYC; Myc proto-oncogene protein
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A, INO80K; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K22197 BAF45A, PHF10; BRG1-associated factor 45A
K22198 BAF45B_C, DPF1_3; BRG1-associated factor 45B/C
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
K11648 SMARCB1, SNF5, INI1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11765 ARID2; AT-rich interactive domain-containing protein 2
K11757 PBRM1, PB1; protein polybromo-1
K11723 BRD7; bromodomain-containing protein 7
|
05226 Gastric cancer [PATH:ko05226]
|
K22234 CDX2; homeobox protein CDX2
K10955 MUC2; mucin-2
K06811 CDH17; cadherin 17, LI cadherin
K22244 REG4; regenerating islet-derived protein 4
K05658 ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K11988 SHH; sonic hedgehog
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K08528 RARB, NR1B2; retinoic acid receptor beta
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K08734 MLH1; DNA mismatch repair protein MLH1
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K05691 CTNNA; catenin alpha
K10056 JUP, PG; junction plakoglobin
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
|
05214 Glioma [PATH:ko05214]
|
05216 Thyroid cancer [PATH:ko05216]
|
05221 Acute myeloid leukemia [PATH:ko05221]
|
05220 Chronic myeloid leukemia [PATH:ko05220]
|
05217 Basal cell carcinoma [PATH:ko05217]
|
05218 Melanoma [PATH:ko05218]
|
05211 Renal cell carcinoma [PATH:ko05211]
|
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03870 CUL2; cullin 2
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K05448 VEGFA; vascular endothelial growth factor A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K17386 PDGFB; platelet-derived growth factor subunit B
K08774 TGFA; transforming growth factor, alpha
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04438 CRK, CRKII; C-crk adapter molecule crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1, pnt; C-ets-1
K04448 JUN; transcription factor AP-1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13105 PRCC; proline-rich protein PRCC
K09105 TFE3; transcription factor E3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K09594 FLCN, BHD; folliculin
|
05219 Bladder cancer [PATH:ko05219]
|
05215 Prostate cancer [PATH:ko05215]
|
05213 Endometrial cancer [PATH:ko05213]
|
05224 Breast cancer [PATH:ko05224]
|
05222 Small cell lung cancer [PATH:ko05222]
|
05223 Non-small cell lung cancer [PATH:ko05223]
|
|
09172 Infectious disease: viral
|
|
09171 Infectious disease: bacterial
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
05132 Salmonella infection [PATH:ko05132]
|
05131 Shigellosis [PATH:ko05131]
|
05135 Yersinia infection [PATH:ko05135]
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
K13730 inlA; internalin A
K13731 inlB; internalin B
K13732 fnbA; fibronectin-binding protein A
K13733 fnbB; fibronectin-binding protein B
K13925 pfbA; plasmin and fibronectin-binding protein A
K13734 sfb1; fibronectin-binding protein 1
K13735 yeeJ; adhesin/invasin
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K13736 ARHGAP10; Rho GTPase-activating protein 10
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04438 CRK, CRKII; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K13737 SEPT1; septin 1
K16942 SEPT2; septin 2
K16938 SEPT3_9_12; septin 3/9/12
K16939 SEPT6_8_11; septin 6/8/11
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K13738 CD2AP; CD2-associated protein
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5]
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K04644 CLTA, LCA; clathrin light chain A
K04645 CLTB, LCB; clathrin light chain B
K04646 CLTC; clathrin heavy chain
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K06106 CTTN, EMS1; cortactin
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K05760 PXN; paxillin
K05717 FN1; fibronectin 1
K06484 ITGA5, CD49e; integrin alpha 5
K05719 ITGB1, CD29; integrin beta 1
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K13287 sipD, ipaD, bipD; invasin D
K13286 sipC, ipaC, bipC; invasin C
K13285 sipB, ipaB, bipB; invasin B
K13739 sopD; secreted effector protein SopD
K13284 sipA, ipaA; invasin A
K13740 sptP; secreted effector protein SptP
K13741 sopE; guanine nucleotide exchange factor SopE
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
K13742 ipgB1; protein IpgB1
K13743 ipgB2; protein IpgB2
K12785 espG, virA; LEE-encoded effector EspG
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K13744 ARHGEF26, SGEF; Rho guanine nucleotide exchange factor 26
K07863 RHOG; Ras homolog gene family, member G
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K19241 ELMO3; engulfment and cell motility protein 3
K04513 RHOA; Ras homolog gene family, member A
K05700 VCL; vinculin
|
|
09174 Infectious disease: parasitic
|
|
09163 Immune disease
|
|
09164 Neurodegenerative disease
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
|
09167 Endocrine and metabolic disease
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
01521 EGFR tyrosine kinase inhibitor resistance [PATH:ko01521]
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K18497 FGF2; fibroblast growth factor 2
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05464 GAS6; growth arrest-specific 6
K05115 AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K09408 FOXO3; forkhead box protein O3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08052 NF1; neurofibromin 1
K02159 BAX; apoptosis regulator BAX
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
|
01524 Platinum drug resistance [PATH:ko01524]
|
01523 Antifolate resistance [PATH:ko01523]
|
01522 Endocrine resistance [PATH:ko01522]
|
|
09180 Brite Hierarchies
|
|
09181 Protein families: metabolism
|
|
09182 Protein families: genetic information processing
|
|
09183 Protein families: signaling and cellular processes
|
02000 Transporters [BR:ko02000]
|
02044 Secretion system [BR:ko02044]
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02042 Bacterial toxins [BR:ko02042]
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02022 Two-component system [BR:ko02022]
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02035 Bacterial motility proteins [BR:ko02035]
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03037 Cilium and associated proteins [BR:ko03037]
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04812 Cytoskeleton proteins [BR:ko04812]
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04147 Exosome [BR:ko04147]
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02048 Prokaryotic defense system [BR:ko02048]
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04030 G protein-coupled receptors [BR:ko04030]
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04050 Cytokine receptors [BR:ko04050]
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04054 Pattern recognition receptors [BR:ko04054]
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03310 Nuclear receptors [BR:ko03310]
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04040 Ion channels [BR:ko04040]
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04031 GTP-binding proteins [BR:ko04031]
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04052 Cytokines and neuropeptides [BR:ko04052]
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04515 Cell adhesion molecules [BR:ko04515]
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04090 CD molecules [BR:ko04090]
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01504 Antimicrobial resistance genes [BR:ko01504]
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00535 Proteoglycans [BR:ko00535]
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00536 Glycosaminoglycan binding proteins [BR:ko00536]
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
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04091 Lectins [BR:ko04091]
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04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
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K23688 BCAR3, SH2D3B; breast cancer anti-estrogen resistance protein 3
K23694 GRAP; GRB2-related adapter protein
K07366 GRAP2, GADS; GRB2-related adaptor protein 2
K23695 GRB7; growth factor receptor-bound protein 7
K23696 GRB14; growth factor receptor-bound protein 14
K23697 SHB_D_E_F; SH2 domain-containing adapter protein B/D/E/F
K23698 SLA; src-like-adapter
K23699 HSH2D; hematopoietic SH2 domain-containing protein
K07990 SH2D1A, SAP; SH2 domain-containing protein 1A
K07989 SH2D1B, EAT2; SH2 domain-containing protein 1B
K08273 SH2D2A, VRAP; SH2 domain-containing protein 2A
K23689 SH2D3A; SH2 domain-containing protein 3A
K23690 SH2D3C; SH2 domain-containing protein 3C
K17577 SH2D4A; SH2 domain-containing protein 4A
K23701 SH2D5; SH2 domain-containing protein 5
K23710 ABI3; abi gene family member 3
K23702 MACC1; metastasis-associated in colon cancer protein 1
K16655 MIA; melanoma inhibitory activity protein
K23703 MIA2, CTAGE5; melanoma inhibitory activity protein 2
K23704 MIA3, TANGO1; transport and golgi organization protein 1
K23705 SASH1; SAM and SH3 domain-containing protein 1
K23706 SASH3; SAM and SH3 domain-containing protein 3
K23707 SAMSN1; SAM domain-containing protein SAMSN-1
K06086 SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing protein 1
K23708 SORBS2; sorbin and SH3 domain-containing protein 2
K23709 SORBS3; vinexin
K23711 STAC; SH3 and cysteine-rich domain-containing protein
K23712 STAC2; SH3 and cysteine-rich domain-containing protein 2
K23713 STAC3; SH3 and cysteine-rich domain-containing protein 3
K23714 SH3D19; SH3 domain-containing protein 19
K23715 SH3D21; SH3 domain-containing protein 21
K23716 VXN; vexin
K20652 SH3BP1, ARHGAP43; SH3-domain binding protein 1
K07984 SH3BP2; SH3-domain binding protein 2
K20066 SH3BP4; SH3 domain-binding protein 4
K23739 SH3BP5; SH3-domain binding protein 5
K23740 SH3BGR; SH3 domain-binding glutamic acid-rich protein
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K16847 TIAM2; T-lymphoma invasion and metastasis-inducing protein 2
K05720 FGD1; FYVE, RhoGEF and PH domain containing 1
K05721 FGD2; FYVE, RhoGEF and PH domain containing 2
K05722 FGD3; FYVE, RhoGEF and PH domain containing 3
K05723 FGD4; FYVE, RhoGEF and PH domain containing 4
K05724 FGD5_6; FYVE, RhoGEF and PH domain containing 5/6
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K23780 GAB3; GRB2-associated-binding protein 3
K23781 ADAP, CENTA; Arf-GAP with dual PH domain-containing protein
K23782 AFAP1L; actin filament associated protein 1-like
K08283 COL4A3BP; collagen type IV alpha-3-binding protein
K17082 FERMT1, KIND1; kindlin 1
K17083 FERMT2, KIND2; kindlin 2
K17084 FERMT3, KIND3; kindlin 3
K23792 MPRIP; myosin phosphatase Rho-interacting protein
K23793 PHLDA; pleckstrin homology-like domain family A
K23794 PHLDB; pleckstrin homology-like domain family B
K23795 IPCEF1; interactor protein for cytohesin exchange factors 1
K15375 PLCL1, PRIP; inactive phospholipase C-like protein 1
K15370 PLCL2; inactive phospholipase C-like protein 2
K23796 PLEKHA1_2; pleckstrin homology domain-containing family A member 1/2
K20313 PLEKHA3, FAPP1; pleckstrin homology domain-containing family A member 3
K23797 PLEKHA4_5_6_7; pleckstrin homology domain-containing family A member 4/5/6/7
K08051 PLEKHA8, FAPP2; pleckstrin homology domain containing family A member 8
K23857 PLEKHB; pleckstrin homology domain-containing family B
K23858 PLEKHF; pleckstrin homology domain-containing family F
K23859 PLEKHG1_2_3; pleckstrin homology domain-containing family G member 1/2/3
K23860 PLEKHG4; pleckstrin homology domain-containing family G member 4
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K23861 PLEKHG6; pleckstrin homology domain-containing family G member 6
K24020 PLEKHH; pleckstrin homology domain-containing family H
K24021 PLEKHJ; pleckstrin homology domain-containing family J
K23282 PLEKHM1; pleckstrin homology domain-containing family M member 1
K15348 PLEKHM2, SKIP; pleckstrin homology domain-containing family M member 2
K24022 PLEKHO; pleckstrin homology domain-containing family O
K24023 RALGPS; Ras-specific guanine nucleotide-releasing factor RalGPS
K23488 RAPH1; Ras-associated and pleckstrin homology domains-containing protein 1
K24024 RTKN; rhotekin
K24025 STAP1; signal-transducing adaptor protein 1
K24026 STAP2; signal-transducing adaptor protein 2
K24027 MELT; protein melted
K14752 DOK1; docking protein 1
K20234 DOK2; docking protein 2
K24036 DOK3; docking protein 3
K24037 DOK4_5_6, IRS5_6; docking protein 4/5/6
K24038 DOK7; docking protein 7
K12461 FRS2; fibroblast growth factor receptor substrate 2
K24039 FRS3; fibroblast growth factor receptor substrate 3
K24035 APBA3, 11L2; amyloid beta A4 precursor protein-binding family A member 3
K04530 APBB2, FE65L; amyloid beta A4 precursor protein-binding family B member 2
K23898 RCN1; reticulocalbin-1
K23899 RCN2; reticulocalbin-2
K23900 RCN3; reticulocalbin-3
K23901 CALU; calumenin
K23531 CABP1_2_4_5; calcium-binding protein 1/2/4/5
K23849 CABP7_8, CALN2_1; calcium-binding protein 7/8
K17259 CIB1; calcium and integrin-binding protein 1
K23837 CIB2; calcium and integrin-binding protein 2
K23838 CIB3; calcium and integrin-binding protein 3
K23839 CIB4; calcium and integrin-binding protein 4
K23850 CRNN; cornulin
K23851 EFCAB6; EF-hand calcium-binding domain-containing protein 6
K23853 EFCAB11; EF-hand calcium-binding domain-containing protein 11
K22827 MICU1; calcium uptake protein 1, mitochondrial
K22828 MICU2; calcium uptake protein 2, mitochondrial
K23843 MICU3; calcium uptake protein 3, mitochondrial
K19932 NCS1; neuronal calcium sensor
K23854 NECAB; N-terminal EF-hand calcium-binding protein
K23846 HPCA; neuron-specific calcium-binding protein hippocalcin
K23847 HPCAL1; hippocalcin-like protein 1
K19936 VSNL1; visinin-like protein 1
K23848 HPCAL4; hippocalcin-like protein 4
K23855 KCNIP; Kv channel-interacting protein
K23758 S100A1; protein S100-A1
K23759 S100A2; protein S100-A2
K23760 S100A3, S100E; protein S100-A3
K23761 S100A4; protein S100-A4
K23762 S100A5, S100D; protein S100-A5
K23764 S100A6; protein S100-A6
K21126 S100A7; protein S100-A7
K21127 S100A8; protein S100-A8
K21128 S100A9; protein S100-A9
K17274 S100A10; protein S100-A10
K23765 S100A11_13, S100C; protein S100-A11/13
K23766 S100A12; protein S100-A12
K23767 S100A14; protein S100-A14
K23768 S100A16, S100F; protein S100-A16
K23769 TCHHL1, S100A17; trichohyalin-like protein 1
K23757 HRNR, FLG3, S100A18; hornerin
K23770 S100B; protein S100-B
K23771 S100P; protein S100-P
K14734 S100G; protein S100-G
K23772 S100Z; protein S100-Z
K14757 CALB1, CALB; calbindin
K23908 CALB2; calretinin
K23909 CAPS; calcyphosin
K23929 EFHB; EF-hand domain-containing family member B
K23029 EFHC1; EF-hand domain-containing protein 1
K23921 EFHD1; EF-hand domain-containing family member D1
K23922 EFHD2; EF-hand domain-containing family member D2
K23912 FSTL1; follistatin-related protein 1
K23915 FSTL5; follistatin-related protein 5
K23923 GCA; grancalcin
K23924 SRI; sorcin
K08328 GUCA1; guanylate cyclase activator 1
K19695 NCALD; neurocalcin delta
K03213 NKD; naked cuticle
K20371 NUCB; nucleobindin
K23925 OCM; oncomodulin
K23902 PDCD6; programmed cell death protein 6
K23905 PEF1; peflin
K06711 PH-4; hypoxia-inducible factor prolyl 4-hydroxylase [EC:1.14.11.-]
K23926 PVALB; parvalbumin alpha
K17199 RASEF, RAB45; Ras and EF-hand domain-containing protein
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K13764 RCVRN; recoverin
K23927 RPTN; repeatin
K04962 RYR2; ryanodine receptor 2
K23928 SCGN; secretagogin
K05747 WAS; Wiskott-Aldrich syndrome protein
K24046 COBLL1; cordon-bleu protein-like 1
K24047 ESPN; espin
K21880 MPP1; MAGUK 55 kDa erythrocyte membrane protein
K24048 MPP2_6; MAGUK p55 subfamily member 2/6
K24049 MPP3_7; MAGUK p55 subfamily member 3/7
K21109 MPP4; MAGUK p55 subfamily member 4
K06091 MPP5, PALS1; MAGUK p55 subfamily member 5
K23783 CNKSR1, CNK1; connector enhancer of kinase suppressor of Ras 1
K17536 CNKSR2, CNK2, KSR2; connector enhancer of kinase suppressor of Ras 2
K23784 CNKSR3, CNK3; connector enhancer of kinase suppressor of Ras 3
K24053 GRASP; general receptor for phosphoinositides 1-associated scaffold protein
K24054 GOPC; golgi-associated PDZ and coiled-coil motif-containing protein
K24055 LRRC7; leucine-rich repeat-containing protein 7
K24057 PDZK1, PDZD1; DZ domain-containing protein 1
K24058 PDZD2; PDZ domain-containing protein 2
K24059 PDZD3; PDZ domain-containing protein 3
K24056 PDZD4; PDZ domain-containing protein 4
K22862 INTU, CPLANE4, PDZD6; protein inturned
K21882 PDZD7; PDZ domain-containing protein 7
K24060 PDZD8; PDZ domain-containing protein 8
K24061 PDZD11; PDZ domain-containing protein 11
K24062 PICK1; PRKCA-binding protein
K24065 SNTG; gamma-syntrophin
K24066 SYNPO2; synaptopodin-2
K24067 TAX1BP3; Tax1-binding protein 3
K27395 PRX; periaxin
K17917 SNX1_2; sorting nexin-1/2
K17918 SNX3_12; sorting nexin-3/12
K17919 SNX4; sorting nexin-4
K17920 SNX5_6_32; sorting nexin-5/6/32
K17921 SNX7_30; sorting nexin-7/30
K17922 SNX8, MVP1; sorting nexin-8
K17923 SNX9_18_33; sorting nexin-9/18/33
K17924 SNX10_11; sorting nexin-10/11
K17925 SNX13; sorting nexin-13
K17926 SNX14; sorting nexin-14
K17927 SNX15; sorting nexin-15
K17928 SNX16; sorting nexin-16
K17929 SNX17; sorting nexin-17
K17930 SNX19; sorting nexin-19
K17931 SNX20; sorting nexin-20
K17932 SNX21; sorting nexin-21
K17941 SNX22_24; sorting nexin-22/24
K17916 KIF16B, SNX23; kinesin family member 16B
K17887 SNX25, MDM1; sorting nexin-25
K17933 ARHGAP33, SNX26; Rho GTPase-activating protein 33
K17936 SNX27; sorting nexin-27
K17934 NOXO1, SNX28; NADPH oxidase organizer 1
K17935 SNX29; sorting nexin-29
K17937 SNX31; sorting nexin-31
K21996 SNX41_42; sorting nexin-41/42
K24094 HS1BP3; HCLS1-binding protein 3
K24095 NISCH; nischarin
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K22751 CBFA2T2; CBFA2/RUNX1 translocation partner 2
K22752 CBFA2T3; CBFA2/RUNX1 translocation partner 3
K24630 ZMYND8; protein kinase C-binding protein 1
K24631 ANKMY1, ZMYD13; ankyrin repeat and MYND domain-containing protein 1
K24632 ZMYND19; zinc finger MYND domain-containing protein 19
K24633 ANKMY2, ZMYND20, DAF25; ankyrin repeat and MYND domain-containing protein 2
K24634 SMYD4, ZMYND21; SET and MYND domain-containing protein 4 [EC:2.1.1.-]
K24635 SMYD5, ZMYND23; SET and MYND domain-containing protein 5 [EC:2.1.1.-]
K24674 ZMYM1; zinc finger MYM-type protein 1
K24676 ZMYM5; zinc finger MYM-type protein 5
K24684 ZFAND1; AN1-type zinc finger protein 1
K24685 ZFAND2; AN1-type zinc finger protein 2
K24686 ZFAND3; AN1-type zinc finger protein 3
K12163 ZFAND4, ANUBL1; AN1-type zinc finger protein 4
K24687 ZFAND5_6; AN1-type zinc finger protein 5/6
K26145 ZSWIM1; zinc finger SWIM domain-containing protein 1
K26146 ZSWIM4; zinc finger SWIM domain-containing protein 4
K26147 ZSWIM5; zinc finger SWIM domain-containing protein 5
K24642 ZBED5_7_8_9, BUSTER; zinc finger BED domain-containing protein 5/7/8/9
K24691 ZNF106; zinc finger protein 106
K26542 ZNF346, JAZ; zinc finger protein 346
K19325 ZNF592; zinc finger protein 592
K24945 ZC3H7; zinc finger CCCH domain-containing protein 7
K25165 HELZ2; helicase with zinc finger domain 2 [EC:3.6.4.-]
K24098 LMO1_3; rhombotin-1/3
K15612 LMO2; rhombotin-2
K24099 LMO4; LIM domain transcription factor LMO4
K24412 CRIP1, CRP1; cysteine-rich protein 1
K24413 CRIP2_3, CRP2_3; cysteine-rich protein 2/3
K14365 FHL1, SLIM1; four and a half LIM domains protein 1
K14380 FHL2; four and a half LIM domains protein 2
K24414 FHL3; four and a half LIM domains protein 3
K24415 FHL5, ACT; four and a half LIM domains protein 5
K23354 LIMS1_2, PINCH1_2; LIM and senescent cell antigen-like-containing domain protein 1/2
K05760 PXN; paxillin
K24314 LPXN; leupaxin
K24315 TGFB1I1; transforming growth factor beta-1-induced transcript 1 protein
K24270 TES; testin
K24417 LMCD1; LIM and cysteine-rich domains protein 1
K23353 PDLIM1_2_3_4; PDZ and LIM domain protein 1/2/3/4
K19867 PDLIM5_6_7; PDZ and LIM domain protein 5/6/7
K24420 LASP1; LIM and SH3 domain protein 1
K24421 NRAP; nebulin-related-anchoring protein
K24416 FBLIM1, FBLP1; filamin-binding LIM protein 1
K24422 LIMCH1; LIM and calponin homology domains-containing protein 1
K24423 ZNF185; zinc finger protein 185
K24424 SCEL; sciellin
K15617 LDB1; LIM domain-binding protein 1
K24143 LDB2; LIM domain-binding protein 2
K07379 CNTNAP1; contactin associated protein 1
K07380 CNTNAP2; contactin associated protein-like 2
K24337 CNTNAP3_4; contactin associated protein-like 3/4
K24338 CNTNAP5; contactin associated protein-like 5
K24341 EGFRAM; pikachurin
K19601 EYS; protein eyes shut
K24342 NELL; protein kinase C-binding protein NELL
K24332 ATRN; attractin
K24333 MEGF6; multiple epidermal growth factor-like domains protein 6
K20051 LRP4, MEGF7; low-density lipoprotein receptor-related protein 4
K23664 MEGF8; multipile epidermal growth factor-like domains protein 8
K24334 MEGF9; multiple epidermal growth factor-like domains protein 9
K24068 MEGF10_11; multiple epidermal growth factor-like domains protein 10/11
K24331 PEAR1, MEGF12; platelet endothelial aggregation receptor 1
K24318 SCARF1; scavenger receptor class F member 1
K24319 SCARF2; scavenger receptor class F member 2
K05717 FN1; fibronectin 1
K01328 F12; coagulation factor XII (Hageman factor) [EC:3.4.21.38]
K24474 BSPH, ELSPBP2; binder of sperm protein
K24475 ELSPBP1; epididymal sperm-binding protein 1
K24477 ABI3BP; target of Nesh-SH3
K24478 ANKFN1; ankyrin repeat and fibronectin type-III domain-containing protein 1
K24479 ASTN; astrotactin
K24480 CMYA5; cardiomyopathy-associated protein 5
K24481 CRLF1; cytokine receptor-like factor 1
K24482 CRLF3; cytokine receptor-like factor 3
K24483 FANK1; fibronectin type 3 and ankyrin repeat domains protein 1
K16362 FLRT; leucine-rich repeat transmembrane protein FLRT
K24484 FNDC1; fibronectin type III domain-containing protein 1
K24485 FNDC3; fibronectin type III domain-containing protein 3
K24486 FNDC4_5; fibronectin type III domain-containing protein 4/5
K24487 FNDC7; fibronectin type III domain-containing protein 7
K24488 FNDC8; fibronectin type III domain-containing protein 8
K24489 FSD1; fibronectin type III and SPRY domain-containing protein 1
K24490 FSD2; fibronectin type III and SPRY domain-containing protein 2
K16354 LRFN1, SALM2; leucine-rich repeat and fibronectin type-III domain-containing protein 1
K16355 LRFN2, SALM1; leucine-rich repeat and fibronectin type-III domain-containing protein 2
K16356 LRFN3, SALM4; leucine-rich repeat and fibronectin type-III domain-containing protein 3
K16357 LRFN4, SALM3; leucine-rich repeat and fibronectin type-III domain-containing protein 4
K16358 LRFN5, SALM5; leucine-rich repeat and fibronectin type-III domain-containing protein 5
K24491 LRIT; leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein
K24492 LRRN1_2_3; leucine-rich repeat neuronal protein 1/2/3
K24493 LRRN4; leucine-rich repeat neuronal protein 4
K24494 MYBPH; myosin-binding protein H
K24495 MYOM; myomesin
K24496 NPHS1; nephron
K24497 PHYHIP; phytanoyl-CoA hydroxylate-interacting protein
K24499 UMODL1; uromodulin-like 1
K24500 VASN; vasorin
K07296 ADIPOQ, ACDC; adiponectin
K24211 C1QTNF2; complement C1q and tumor necrosis factor-related protein 2
K24212 C1QTNF5; complement C1q and tumor necrosis factor-related protein 5
K24218 C1QTNF7; complement C1q and tumor necrosis factor-related protein 7
K24213 C1QTNF9; complement C1q and tumor necrosis factor-related protein 9
K24214 OTOL1; otolin-1
K24235 CBLN; cerebellin
K19470 C1QTNF1_6_8; complement C1q tumor necrosis factor-related protein 1/6/8
K24236 C1QTNF3; complement C1q and tumor necrosis factor-related protein 3
K24237 C1QTNF4; complement C1q and tumor necrosis factor-related protein 4
K21410 C1QTNF12, FAM132A; adipolin
K24381 ERFE, FAM132B; erythroferrone
K24246 EMILIN; emilin
K24247 MMRN; multimerin
K24248 EMID1; EMI domain-containing protein 1
K24358 COL26A, EMID2; collagen type XXVI alpha (EMI domain-containing protein 2)
K24427 SPON1; spondin-1
K24428 SPON2; spondin-2
K24429 ADAMTSL1_3; ADAMTS-like protein 1/3
K24430 ADAMTSL2; ADAMTS-like protein 2
K23369 ADAMTSL4; ADAMTS-like protein 4
K24432 ADAMTSL5; ADAMTS-like protein 5
K23377 THSD4, ADAMTSL6; thrombospondin type-1 domain-containing protein 4
K24433 THSD1; thrombospondin type-1 domain-containing protein 1
K24434 SSPO; SCO-spondin
K24435 ISM; isthmin
K24436 CILP; cartilage intermediate layer protein
K24437 TSEAR; thrombospondin-type laminin G domain and EAR repeat-containing protein
K24461 DLK1; protein delta homolog 1
K24462 DLK2, EGFL9; protein delta homolog 2
K24463 DNER; delta and Notch-like epidermal growth factor-related receptor
K24469 SVEP1; sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1
K06826 NID; nidogen (entactin)
K24431 OPA3; oncoprotein-induced transcript 3 protein
K17307 FBLN1_2; fibulin 1/2
K18262 EFEMP1, FBLN3; EGF-containing fibulin-like extracellular matrix protein 1
K19866 EFEMP2; EGF-containing fibulin-like extracellular matrix protein 2
K17340 FBLN5; fibulin 5
K17341 HMCN; hemicentin
K17342 FBLN7; fibulin 7
K24464 EDIL3; EGF-like repeat and discoidin I-like domain-containing protein 3
K24465 EGFL7_8; epidermal growth factor-like protein 7/8
K19559 LTBP1; latent transforming growth factor beta binding protein 1
K08023 LTBP2_3_4; latent transforming growth factor beta binding protein 2/3/4
K24466 NOTCH2NL; Notch homolog 2 N-terminal-like protein
K24467 PROZ; vitamin K-dependent protein Z
K24468 SCUBE1_3; signal peptide, CUB and EGF-like domain-containing protein 1/3
K24470 SNED1, IRE-BP1; insulin-responsive sequence DNA-binding protein 1
K24471 EPGN; epigen
K24473 TENM, ODZ; teneurin
K19467 MATN; matrilin
K23574 COCH; cochlin
K24506 VIT; vitrin
K24507 VWA1; von Willebrand factor A domain-containing protein 1
K24508 VWA2; von Willebrand factor A domain-containing protein 2
K24509 VWA3; von Willebrand factor A domain-containing protein 3
K24510 VWA5; von Willebrand factor A domain-containing protein 5
K24511 VWA7; von Willebrand factor A domain-containing protein 7
K24512 VWA8; von Willebrand factor A domain-containing protein 8
K24514 ITIH4; inter-alpha-trypsin inhibitor heavy chain H4
K24515 ITIH5; inter-alpha-trypsin inhibitor heavy chain H5
K24516 ITIH6; inter-alpha-trypsin inhibitor heavy chain H6
K24524 CPNE1_2_3; copine 1/2/3
K24525 CPNE4_6_7; copine 4/6/7
K24523 CPNE5_8_9; copine 5/8/9
K24517 BMPER; BMP-binding endothelial regulator protein
K24518 CRIM1; cysteine-rich motor neuron 1 protein
K24519 VWCE; von Willebrand factor C and EGF domain-containing protein
K24520 CHRDL1; chordin-like protein 1
K24521 VWC2; brorin
K24522 KCP; kielin/chordin-like protein
K24728 CFAP52, WDR16; cilia- and flagella-associated protein 52
K24729 CFAP57, WDR65; cilia- and flagella-associated protein 57
K24725 AAMP; angio-associated migratory cell protein
K24730 CIAO1, CIA1; cytosolic iron-sulfur protein assembly protein CIAO1
K24731 DMWD; dystrophia myotonica WD repeat-containing protein
K24732 GNB1L; guanine nucleotide-binding protein subunit beta-like protein 1
K24733 LRWD1; leucine-rich repeat and WD repeat-containing protein 1
K24734 NWD; NACHT domain- and WD repeat-containing protein
K24735 SPAG16; sperm-associated antigen 16 protein
K24736 WDR1, AIP1; WD repeat-containing protein 1 (actin-interacting protein 1)
K24737 WDR6; WD repeat-containing protein 6
K24739 WDR13; WD repeat-containing protein 13
K24740 WDR17; WD repeat-containing protein 17
K24741 WDR20; WD repeat-containing protein 20
K24742 WDR25; WD repeat-containing protein 25
K24743 WDR31; WD repeat-containing protein 31
K24744 WDR37; WD repeat-containing protein 37
K24745 WDR38; WD repeat-containing protein 38
K24746 WDR47; WD repeat-containing protein 47
K24747 WDR49; WD repeat-containing protein 49
K24748 WDR53; WD repeat-containing protein 53
K24749 WDR54; WD repeat-containing protein 54
K24750 WDR55, JIP5; WD repeat-containing protein 55
K24751 WDR64; WD repeat-containing protein 64
K24753 WDR72; WD repeat-containing protein 72
K24754 WDR73; WD repeat-containing protein 73
K24756 WDR86; WD repeat-containing protein 86
K24757 WDR88; WD repeat-containing protein 88
K24758 WDR89; WD repeat-containing protein 89
K24762 WDR93; WD repeat-containing protein 93
K24764 WDSUB1; WD repeat, SAM and U-box domain-containing protein 1
K24765 CREC; catabolite repression protein CreC
K24774 FNBP4; formin-binding protein 4
K19329 WWOX; WW domain-containing oxidoreductase
K24775 WBP1; WW domain-binding protein 1
K22524 WBP2; WW domain-binding protein 2
K24779 ZFYVE21; zinc finger FYVE domain-containing protein 21
K19600 TUB, TULP; tubby and related proteins
K24720 TULP4; tubby-related protein 4
K23961 EPB41L1_2_3; band 4.1-like protein 1/2/3
K23962 EPB41L4A, NBL4; band 4.1-like protein 4A
K21111 EPB41L4B, EHM2, LULU2; band 4.1-like protein 4B
K23963 EPB41L5; band 4.1-like protein 5
K23954 FRMPD1; FERM and PDZ domain-containing protein 1
K23955 FRMPD2; FERM and PDZ domain-containing protein 2
K23959 FRMPD3; FERM and PDZ domain-containing protein 3
K23956 FRMPD4; FERM and PDZ domain-containing protein 4
K16821 FRMD1; FERM domain-containing protein 1
K23969 FRMD3_5; FERM domain-containing protein 3/5
K23970 FRMD4; FERM domain-containing protein 4
K16822 FRMD6; FERM domain-containing protein 6
K23971 FRMD7; FERM domain-containing protein 7
K23972 FRMD8; FERM domain-containing protein 8
K24783 JAKMIP1; janus kinase and microtubule-interacting protein 1
K24784 JAKMIP2; janus kinase and microtubule-interacting protein 2
K24785 JAKMIP3; janus kinase and microtubule-interacting protein 3
K24786 RUNDC1; RUN domain-containing protein 1
K24787 RUNDC3; RUN domain-containing protein 3
K24682 PTCHD; patched domain-containing protein
K24680 DISP1; protein dispatched 1
K24681 DISP2; protein dispatched 2
K24683 DISP3, PTCHD2; protein dispatched 3
K19897 FAS1; fasciclin 1
K19519 TGFBI, BIGH3; transforming growth factor-beta-induced protein
K24790 POSTN; periostin
K24792 CDCP2; CUB domain-containing protein 2
K24793 CUZD1; CUB and zona pellucida-like domain-containing protein 1
K24794 DCBLD; discoidin, CUB and LCCL domain-containing protein
K23091 KREMEN; kremen protein
K24359 MFRP; membrane frizzled-related protein
K24360 NETO; neuropilin and tolloid-like protein
K24361 PCOLCE; procollagen C-endopeptidase enhancer
K24362 PAMR1; inactive serine protease PAMR1
K24363 SEZ6; seizure protein 6
K23818 SRPX; sushi repeat-containing protein SRPX
K19408 SRPX2; sushi repeat-containing protein SRPX2
K23819 SUSD1; sushi domain-containing protein 1
K23820 SUSD2; sushi domain-containing protein 2
K23821 SUSD3; sushi domain-containing protein 3
K23822 SUSD4; sushi domain-containing protein 4
K23823 SUSD5; sushi domain-containing protein 5
K23824 SUSD6; sushi domain-containing protein 6
K24808 BTBD17; BTB/POZ domain-containing protein 17
K24811 BTBD18; BTB/POZ domain-containing protein 18
K24809 CCIN; calicin
K24810 IBTK; inhibitor of Bruton tyrosine kinase
K24812 HEATR3; HEAT repeat-containing protein 3
K24813 HEATR4; HEAT repeat-containing protein 4
K24815 HEATR6; HEAT repeat-containing protein 6
K24816 MROH1, HEATR7A; maestro heat-like repeat-containing protein family member 1
K24817 MROH2, HEATR7B; maestro heat-like repeat-containing protein family member 2
K24818 RIPOR, FAM65; Rho family-interacting cell polarization regulator
K24124 ARMC3; armadillo repeat-containing protein 3
K24166 ARMC6; armadillo repeat-containing protein 6
K24167 ARMC10; armadillo repeat-containing protein 10
K24168 ARMC12; armadillo repeat-containing protein 12
K24169 THADA, ARMC13; thyroid adenoma-associated protein
K26233 ARMCX5; armadillo repeat-containing X-linked protein 5
K26234 BHLHB9, GPRASP3; G-protein coupled receptor-associated sorting protein 3
K24848 IFIT2; interferon-induced protein with tetratricopeptide repeats 2
K24849 IFIT3; interferon-induced protein with tetratricopeptide repeats 3
K24924 RAPSN; receptor-associated protein of the synapse
K24044 RGPD; RANBP2-like and GRIP domain-containing protein
K24929 TTC6; tetratricopeptide repeat protein 6
K24930 TTC9; tetratricopeptide repeat protein 9
K24933 TTC22; tetratricopeptide repeat protein 22
K24935 TTC27; tetratricopeptide repeat protein 27
K24946 TTC32; tetratricopeptide repeat protein 32
K24947 TTC34; tetratricopeptide repeat protein 34
K24942 TTC38; tetratricopeptide repeat protein 38
K24943 TTC39; tetratricopeptide repeat protein 39
K24944 TTC41; tetratricopeptide repeat protein 41
K24979 BOLL; protein boule-like
K24980 DAZ; deleted in azoospermia protein
K24981 DND1; dead end 1
K24982 ENOX; ecto-NOX disulfide-thiol exchanger
K17392 IGF2BP2; insulin-like growth factor 2 mRNA-binding protein 2
K24990 RBMS; RNA-binding motif, single-stranded-interacting protein
K24991 MTHFSD; methenyltetrahydrofolate synthase domain-containing protein
K24994 RALYL; RNA-binding Raly-like protein
K25000 RAVER2; ribonucleoprotein PTB-binding 2
K25078 RBM33; RNA-binding protein 33
K25079 RBM42; RNA-binding protein 42
K25080 RBM44; RNA-binding protein 44
K25081 RBM45; RNA-binding protein 45
K25082 RBM46; RNA-binding protein 46
K25083 RBM47; RNA-binding protein 47
K25095 SLIRP; SRA stem-loop-interacting RNA-binding protein, mitochondrial
K25093 SLTM; SAFB-like transcription modulator
K24834 GLIPR1; glioma pathogenesis-related protein 1
K24835 GLIPR2; glioma pathogenesis-related protein 2
K24836 PI15, CRISP8; peptidase inhibitor 15
K24243 CRISPLD; cysteine-rich secretory protein LCCL domain-containing
K24837 IQCA, DRC11; dynein regulatory complex subunit 11
K24839 IQCD, DRC10; dynein regulatory complex subunit 10
K24840 IQCF; IQ domain-containing protein F
K24841 IQCG, DRC9; dynein regulatory complex subunit 9
K24842 IQCH; IQ domain-containing protein H
K24832 IQCJ; IQ domain-containing protein J
K24838 IQUB; IQ and ubiquitin-like domain-containing protein
K23728 CCDC65, DRC2; dynein regulatory complex subunit 2
K26405 CCDC25; coiled-coil domain-containing protein 25
K23729 CCDC39; coiled-coil domain-containing protein 39
K23730 CCDC40; coiled-coil domain-containing protein 40
K23731 CCDC103; coiled-coil domain-containing protein 103
K23930 FAM83; protein FAM83
K24828 LCA5; lebercilin
K24822 LOXHD1; lipoxygenase homology domain-containing protein 1
K24127 MAGE; melanoma-associated antigen
K24829 MINAR1; major intrinsically disordered Notch2-binding receptor 1
K24830 MINAR2; major intrinsically disordered Notch2-binding receptor 2
K24833 SCHP1; schwannomin-interacting protein 1
K24831 ZAN; zonadhesin
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)